Gene Symbol | Dido1 |
Entrez Gene ID | 23856 |
Full Name | death inducer-obliterator 1 |
Synonyms | 6720461J16Rik,D130048F08Rik,DATF-1,DIO-1,Datf1,dido |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome | |
Summary | This gene encodes a transcription factor involved in apoptosis. The encoded protein functions in cell cycle progression and plays a role in chromosomal stability. This protein regulates the self-renewal of embryonic stem cells. Disruption of this gene in mice causes symptoms similar to myelodysplastic/myeloproliferative diseases in humans. Mice lacking this gene show severely reduced fertility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]. |