Plcg2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Plcg2
Entrez Gene ID	234779
Full Name	phospholipase C, gamma 2
Synonyms	PLC-gamma-2,PLCgamma2,Plcg-2
General protein information	Preferred Names phospholipase C, gamma 2 Names 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 phosphoinositide phospholipase C-gamma-2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8 E1\|8 64.26 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_172285.1	NP_758489.1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
NM_172285.2	NP_758489.1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	PLCG2	XP_004944314.1
Homo sapiens (human)	PLCG2	NP_002652.2
Pan troglodytes (chimpanzee)	PLCG2	XP_001148089.1
	PLCG2	XP_001111717.1
Mus musculus (house mouse)	Plcg2	NP_758489.1
Arabidopsis thaliana (thale cress)	PLC5	NP_200677.2
Xenopus tropicalis (tropical clawed frog)	plcg2	XP_002934994.2
Bos taurus (cattle)	PLCG2	XP_003587251.2
Danio rerio (zebrafish)	plcg2	NP_001038433.1
Canis lupus familiaris (dog)	PLCG2	XP_005620713.1
Rattus norvegicus (Norway rat)	Plcg2	NP_058864.1

Gene Ontology
Bibliography

Related articles in PubMed

Spleen tyrosine kinase influences the early stages of multilineage differentiation of bone marrow stromal cell lines by regulating phospholipase C gamma activities.
Kusuyama J, Kamisono A, ChangHwan S, Amir MS, Bandow K, Eiraku N, Ohnishi T, Matsuguchi T
Journal of cellular physiology233(3)2549-2559(2018 Mar)

PLC?-dependent mTOR signalling controls IL-7-mediated early B cell development.
Yu M, Chen Y, Zeng H, Zheng Y, Fu G, Zhu W, Broeckel U, Aggarwal P, Turner A, Neale G, Guy C, Zhu N, Chi H, Wen R, Wang D
Nature communications8(1)1457(2017 Nov)

TULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of Syk.
Reppschl?ger K, Gosselin J, Dangelmaier CA, Thomas DH, Carpino N, McKenzie SE, Kunapuli SP, Tsygankov AY
The Journal of biological chemistry291(43)22427-22441(2016 Oct)

Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer.
D'Amico L, Mahajan S, Capietto AH, Yang Z, Zamani A, Ricci B, Bumpass DB, Meyer M, Su X, Wang-Gillam A, Weilbaecher K, Stewart SA, DeNardo DG, Faccio R
The Journal of experimental medicine213(5)827-40(2016 May)

Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo.
N?meth T, Futosi K, Sitaru C, Ruland J, M?csai A
Nature communications711004(2016 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Syk-induced signals in bone marrow stromal cell lines are mediated by phospholipase C gamma1 (PLCgamma1) in osteogenesis and PLCgamma2 in adipogenesis.
Title: Spleen tyrosine kinase influences the early stages of multilineage differentiation of bone marrow stromal cell lines by regulating phospholipase C gamma activities.

PLCgamma2 in clear cells plays an essential role in luminal expansion of the epididymis during the prepubertal period in mice
Title: Phospholipase C?2 Is Required for Luminal Expansion of the Epididymal Duct during Postnatal Development in Mice.

Results show that mice with the mutated Plcg2 gene were less prone to transformation into MALT lymphomas as a result of elevated Treg numbers, and decrease of pro-inflammatory cytokines.
Title: A Gain-Of-Function Mutation in the Plcg2 Gene Protects Mice from Helicobacter felis-Induced Gastric MALT Lymphoma.

platelet activation through GPVI and alphaIIbbeta3 utilizes PLCgamma2 because PLCgamma1 levels are insufficient to support responsiveness, but that PLCgamma1 can restore responsiveness if expressed at levels normally achieved by PLCgamma2.
Title: Restoration of responsiveness of phospholipase C?2-deficient platelets by enforced expression of phospholipase C?1.

amarogentin prevents platelet activation through the inhibition of PLC gamma2-PKC cascade and MAPK pathway
Title: Amarogentin, a secoiridoid glycoside, abrogates platelet activation through PLC ? 2-PKC and MAPK pathways.

The following Plcg2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Plcg2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18551	NM_172285.1 Latest version!	Mus musculus phospholipase C, gamma 2 (Plcg2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	16	$643.30 $919.00
OMu83524	NM_172285.2 Latest version!	Mus musculus phospholipase C, gamma 2 (Plcg2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Plcg2 ( NM_172285.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_758489.1 Mus musculus phospholipase C, gamma 2 (Plcg2), mRNA.

Price & Availability↑

CloneID	OMu18551
Clone ID Related Accession (Same CDS sequence)	NM_172285.1
Accession Version	NM_172285.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-14
Organism	Mus musculus(House mouse)
Product	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
Comment

ATGACCACCA TGGTCAACGT GGACACCCTT CCAGAATATG AGAAGAGTCA GATCAAGAGA 
GCGCTGGAGT TAGGGACGGT GATGACCGTG TTCAACGCCC GCAAATCCAC CCCAGAGCGG 
AGGACAGTAC AGATGATCAT GGAGACTCGG CAGGTGGCAT GGAGCAAGAC CGCAGACAAG 
ATTGAAGGCT TCCTGGACAT CATGGAGATA AAGGAAATCC GTCCGGGGAA GAACTCCAAG 
GACTTTGAGC GAGCCAAGGC TGTCCGCCAC AAGGCAGAAT GTTGCTTCAC CATCCTCTAC 
GGCACCCAGT TTGTCCTCAG CACGCTCAGT TTGGCAACGG ACTCAAAGGA GGATGCGGTG 
AAGTGGCTCT CTGGTTTGAA GATCCTACAC CAGGAAGCGA TGAGTGCATC CACCCCCACA 
ATGATTGAGA GTTGGCTGAG AAAACAGATT TATTCAGTAG ATCAAACCCG AAGAAACAGC 
ATCAGCCTCC GGGAGCTGAA GACCATCTTG CCCCTGGTCA ACTTCAAAGT GAGCGGCATC 
AAGTTTCTCA AGGACAAGCT GGTGGAAATC GGCGCACAGA AAGATGAGCT CAGCTTTGAA 
CAGTTCCATC TCTTCTATAA GAAACTCATG TTTGACCAGC AAAAATCGAT ACTTGACGAA 
TTCAAAAAAG ACTCCTCCGT GTTCATCCTA GGAAACACAG ACCGGCCGGA TGCCTCGGCT 
GTCTACCTGC AGGACTTCCA AAGGTTTCTT TTACATGAAC AGCAGGAGCT ATGGGCTCAG 
GATCTGAACA AAGTCCGGGA GCGGATGACC AAGTTTATCG ACGACACAAT GAGAGAGACC 
GCAGAGCCCT TCTTATTTGT GGATGAGTTC CTCACGTATC TGTTCTCCCG GGAGAACAGC 
ATCTGGGACG AGAAGTACGA TGCAGTGGAC ATGCAGGACA TGAACAACCC CTTGTCCCAC 
TACTGGATCT CCTCTTCCCA CAACACGTAC CTCACTGGGG ACCAGCTGCG TAGTGAGTCC 
TCCACGGAAG CGTATATCCG CTGTCTGCGC GCTGGTTGCC GCTGCATTGA GCTGGACTGC 
TGGGACGGGC CTGATGGGAA GCCCATTATC TACCACGGCT GGACACGGAC CACCAAGATC 
AAGTTTGATG ATGTTGTTCA GGCCATCCGA GACCACGCCT TTGTTACCTC CAGCTTCCCC 
GTCATCTTGT CTATCGAGGA GCACTGCAGT GTGGAGCAGC AACGTCACAT GGCCAAGGTG 
TTCAAGGAAG TGTTAGGAGA CATGCTGTTG ACGAAGCCCA CAGAGGCCAG TGCTGACCAG 
CTGCCCTCGC CCAGTCAGCT TCGTGAGAAG ATCATTATCA AGCATAAGAA GCTGGGTCCC 
AAGGGTGATG TCGACGTCAA CGTGGAGGAC AAGAAAGATG AGCACAAGCC CCAGGGCGAG 
CTGTATATGT GGGACTCCAT CGACCAGAAA TGGACGCGCC ACTACTGTGC CATTGCTGAC 
GCCAAGCTGT CCTTCGGTGA TGACATTGAA CAGGCTGTGG AGGAGGAGCC GGTCCAGGAC 
ACTCCCCCCA CGGAGCTGCA TTTTGGGGAG AAATGGTTCC ACAAGAAGGT GGAGAGTAGG 
ACCAGTGCGG AGAAGCTGCT GCAAGAGTAC TGTGCTGAGA CCGGGGCCAA GGACGGCACC 
TTCCTGGTGC GGGAGAGCGA GACCTTCCCC AATGACTACA CACTCTCCTT CTGGCGGTCT 
GGCCGGGTGC AGCACTGCCG GATCCGGTCT ACTATGGAGA ATGGGGTCAT GAAGTACTAC 
CTGACCGACA ACCTCACGTT CAACAGCATC TACGCCCTCA TCCAGCACTA CCGTGAGGCA 
CACCTGCGCT GCGCGGAGTT CGAGCTGCGG CTCACAGACC CGGTGCCCAA CCCCAACCCA 
CACGAGTCCA AGCCGTGGTA CTATGACAGT CTGAGCAGGG GGGAAGCGGA GGACATGCTG 
ATGCGGATCC CCCGAGATGG AGCCTTCCTC ATCCGGAAGA GGGAGGGGAC CAACTCCTAC 
GCCATCACCT TCAGGGCCAG GGGCAAGGTG AAACATTGTC GCATCAACCG GGACGGACGC 
CACTTCGTGC TGGGCACCTC TGCCTACTTT GAGAGCCTAG TGGAGCTTGT CAGCTACTAC 
GAGAAGCACG CGCTCTATCG CAAGATGAGG CTTCGATACC CCGTGACCCC GGAGCTCCTG 
GAGCGATATA ATATGGAAAG AGACATCAAC TCTCTTTATG ACGTCAGCAG GATGTATGTG 
GACCCAAGTG AGATCAACCC TTCCATGCCT CAGAGGACCG TGAAAGCGCT CTATGACTAC 
AAAGCCAAGC GCAGCGACGA GCTGACCTTC TGCCGCGGTG CCCTCATCCA CAATGTCTCC 
AAGGAGCCCG GGGGATGGTG GAAAGGGGAC TACGGGACCC GGATCCAGCA GTACTTCCCG 
TCCAACTATG TCGAGGATAT CTCGGCAGGC GATGCTGAGG AGATGGAAAA GCAGATTATT 
GAAGACAATC CCCTCGGGTC TCTCTGCAAA GGCATATTGG ATCTTAATAC CTACAACGTT 
GTGAAGGCCC CCCAGGGGAA AAACCAGAAA GCCTTCGTCT TTATCCTGGA GCCTAAGAAA 
CAGGGAGATC CTCCCGTGGA GTTCGCGACC GACCGTGTGG AGGAGCTGTT TGAGTGGTTT 
CAGAGCATAC GGGAGATCAC TTGGAAGATG GACACCAAGG AGAACAACAT GAAGTACTGG 
GAGAGGAACC AGTCCATCGC CATTGAGCTC TCGGACTTGG TTGTATACTG CAAGCCAACT 
AGCAAAACCA AGGACCATTT GGAAAATCCC GACTTCCGAG AAATCCGCTC TTTTGTGGAG 
ACGAAGGCAG ACAGCATTGT CAGGCAAAAA CCTGTCGATC TATTGCGATA CAATCAGAAG 
GGCCTGACCC GAGTCTACCC CAAGGGACAG AGAGTTGACT CTTCGAACTA TGACCCCTTC 
CGTCTGTGGC TGTGCGGCTC CCAGATGGTG GCACTCAATT TCCAGACTCC AGACAAATAC 
ATGCAGATGA ACCACGCGCT GTTTTCGCTC AATGGGCGAA CAGGCTACGT CCTGCAGCCT 
GAGAGCATGC GCTCTGAGAA GTATGATCCG ATGCCCCTGG AGTCCCAGAG GAAGATCCTG 
ATGACACTCA CTGTCAAGGT TCTTGGTGCA CGCCACCTCC CTAAACTAGG GCGGAGTATT 
GCCTGTCCTT TTGTGGAGGT GGAAATCTGC GGGGCTGAGT ATGACAGCAA CAAATTCAAG 
ACGACGGTTG TGAATGACAA TGGCCTCAGC CCTGTCTGGG CTCCAACTCA GGAGAAGGTG 
ACATTTGAGA TCTATGATCC AAACCTTGCC TTCCTACGCT TTGTGGTCTA CGAAGAAGAC 
ATGTTCAGTG ATCCCAACTT CCTGGCTCAT GCCACGTACC CCATTAAAGG CATCAAATCC 
GGGTTTAGAT CAGTCCCTCT GAAGAATGGG TACAGTGAAG ACATCGAGCT GGCATCCCTC 
CTGGTTTTCT GTGAGATGAG GCCAGTCCTG GAGAGTGAAG AGGAACTCTA TTCCTCCTGT 
CGCCAACTGC GGAGGCGGCA AGAAGAGCTC AACAACCAGC TCTTCCTTTA CGACACGCAC 
CAGAACCTGC GCGGAGCCAA CCGTGATGCC CTGGTGAAGG AGTTCAATGT TAACGAGAAT 
CAGCTGCAGC TGTACCAGGA GAAGTGCAAC CGGAGGCTGA GAGAGAAGAG AGTAAGCAAC 
AGCAGGTTCT ACTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_758489.1

Translation

MTTMVNVDTLPEYEKSQIKRALELGTVMTVFNARKSTPERRTVQMIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAKAVRHKAECCFTILYGTQFVLSTLSLATDSKEDAVKWLSGLKILHQEAMSASTPTMIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSGIKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFDQQKSILDEFKKDSSVFILGNTDRPDASAVYLQDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMAKVFKEVLGDMLLTKPTEASADQLPSPSQLREKIIIKHKKLGPKGDVDVNVEDKKDEHKPQGELYMWDSIDQKWTRHYCAIADAKLSFGDDIEQAVEEEPVQDTPPTELHFGEKWFHKKVESRTSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMENGVMKYYLTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGTNSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQIIEDNPLGSLCKGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFEWFQSIREITWKMDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSFVETKADSIVRQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPLESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLQLYQEKCNRRLREKRVSNSRFYS

Target ORF information:

RefSeq Version	NM_172285.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus phospholipase C, gamma 2 (Plcg2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172285.1

ORF Insert Sequence:

ATGACCACCA TGGTCAACGT GGACACCCTT CCAGAATATG AGAAGAGTCA GATCAAGAGA 
GCGCTGGAGT TAGGGACGGT GATGACCGTG TTCAACGCCC GCAAATCCAC CCCAGAGCGG 
AGGACAGTAC AGATGATCAT GGAGACTCGG CAGGTGGCAT GGAGCAAGAC CGCAGACAAG 
ATTGAAGGCT TCCTGGACAT CATGGAGATA AAGGAAATCC GTCCGGGGAA GAACTCCAAG 
GACTTTGAGC GAGCCAAGGC TGTCCGCCAC AAGGCAGAAT GTTGCTTCAC CATCCTCTAC 
GGCACCCAGT TTGTCCTCAG CACGCTCAGT TTGGCAACGG ACTCAAAGGA GGATGCGGTG 
AAGTGGCTCT CTGGTTTGAA GATCCTACAC CAGGAAGCGA TGAGTGCATC CACCCCCACA 
ATGATTGAGA GTTGGCTGAG AAAACAGATT TATTCAGTAG ATCAAACCCG AAGAAACAGC 
ATCAGCCTCC GGGAGCTGAA GACCATCTTG CCCCTGGTCA ACTTCAAAGT GAGCGGCATC 
AAGTTTCTCA AGGACAAGCT GGTGGAAATC GGCGCACAGA AAGATGAGCT CAGCTTTGAA 
CAGTTCCATC TCTTCTATAA GAAACTCATG TTTGACCAGC AAAAATCGAT ACTTGACGAA 
TTCAAAAAAG ACTCCTCCGT GTTCATCCTA GGAAACACAG ACCGGCCGGA TGCCTCGGCT 
GTCTACCTGC AGGACTTCCA AAGGTTTCTT TTACATGAAC AGCAGGAGCT ATGGGCTCAG 
GATCTGAACA AAGTCCGGGA GCGGATGACC AAGTTTATCG ACGACACAAT GAGAGAGACC 
GCAGAGCCCT TCTTATTTGT GGATGAGTTC CTCACGTATC TGTTCTCCCG GGAGAACAGC 
ATCTGGGACG AGAAGTACGA TGCAGTGGAC ATGCAGGACA TGAACAACCC CTTGTCCCAC 
TACTGGATCT CCTCTTCCCA CAACACGTAC CTCACTGGGG ACCAGCTGCG TAGTGAGTCC 
TCCACGGAAG CGTATATCCG CTGTCTGCGC GCTGGTTGCC GCTGCATTGA GCTGGACTGC 
TGGGACGGGC CTGATGGGAA GCCCATTATC TACCACGGCT GGACACGGAC CACCAAGATC 
AAGTTTGATG ATGTTGTTCA GGCCATCCGA GACCACGCCT TTGTTACCTC CAGCTTCCCC 
GTCATCTTGT CTATCGAGGA GCACTGCAGT GTGGAGCAGC AACGTCACAT GGCCAAGGTG 
TTCAAGGAAG TGTTAGGAGA CATGCTGTTG ACGAAGCCCA CAGAGGCCAG TGCTGACCAG 
CTGCCCTCGC CCAGTCAGCT TCGTGAGAAG ATCATTATCA AGCATAAGAA GCTGGGTCCC 
AAGGGTGATG TCGACGTCAA CGTGGAGGAC AAGAAAGATG AGCACAAGCC CCAGGGCGAG 
CTGTATATGT GGGACTCCAT CGACCAGAAA TGGACGCGCC ACTACTGTGC CATTGCTGAC 
GCCAAGCTGT CCTTCGGTGA TGACATTGAA CAGGCTGTGG AGGAGGAGCC GGTCCAGGAC 
ACTCCCCCCA CGGAGCTGCA TTTTGGGGAG AAATGGTTCC ACAAGAAGGT GGAGAGTAGG 
ACCAGTGCGG AGAAGCTGCT GCAAGAGTAC TGTGCTGAGA CCGGGGCCAA GGACGGCACC 
TTCCTGGTGC GGGAGAGCGA GACCTTCCCC AATGACTACA CACTCTCCTT CTGGCGGTCT 
GGCCGGGTGC AGCACTGCCG GATCCGGTCT ACTATGGAGA ATGGGGTCAT GAAGTACTAC 
CTGACCGACA ACCTCACGTT CAACAGCATC TACGCCCTCA TCCAGCACTA CCGTGAGGCA 
CACCTGCGCT GCGCGGAGTT CGAGCTGCGG CTCACAGACC CGGTGCCCAA CCCCAACCCA 
CACGAGTCCA AGCCGTGGTA CTATGACAGT CTGAGCAGGG GGGAAGCGGA GGACATGCTG 
ATGCGGATCC CCCGAGATGG AGCCTTCCTC ATCCGGAAGA GGGAGGGGAC CAACTCCTAC 
GCCATCACCT TCAGGGCCAG GGGCAAGGTG AAACATTGTC GCATCAACCG GGACGGACGC 
CACTTCGTGC TGGGCACCTC TGCCTACTTT GAGAGCCTAG TGGAGCTTGT CAGCTACTAC 
GAGAAGCACG CGCTCTATCG CAAGATGAGG CTTCGATACC CCGTGACCCC GGAGCTCCTG 
GAGCGATATA ATATGGAAAG AGACATCAAC TCTCTTTATG ACGTCAGCAG GATGTATGTG 
GACCCAAGTG AGATCAACCC TTCCATGCCT CAGAGGACCG TGAAAGCGCT CTATGACTAC 
AAAGCCAAGC GCAGCGACGA GCTGACCTTC TGCCGCGGTG CCCTCATCCA CAATGTCTCC 
AAGGAGCCCG GGGGATGGTG GAAAGGGGAC TACGGGACCC GGATCCAGCA GTACTTCCCG 
TCCAACTATG TCGAGGATAT CTCGGCAGGC GATGCTGAGG AGATGGAAAA GCAGATTATT 
GAAGACAATC CCCTCGGGTC TCTCTGCAAA GGCATATTGG ATCTTAATAC CTACAACGTT 
GTGAAGGCCC CCCAGGGGAA AAACCAGAAA GCCTTCGTCT TTATCCTGGA GCCTAAGAAA 
CAGGGAGATC CTCCCGTGGA GTTCGCGACC GACCGTGTGG AGGAGCTGTT TGAGTGGTTT 
CAGAGCATAC GGGAGATCAC TTGGAAGATG GACACCAAGG AGAACAACAT GAAGTACTGG 
GAGAGGAACC AGTCCATCGC CATTGAGCTC TCGGACTTGG TTGTATACTG CAAGCCAACT 
AGCAAAACCA AGGACCATTT GGAAAATCCC GACTTCCGAG AAATCCGCTC TTTTGTGGAG 
ACGAAGGCAG ACAGCATTGT CAGGCAAAAA CCTGTCGATC TATTGCGATA CAATCAGAAG 
GGCCTGACCC GAGTCTACCC CAAGGGACAG AGAGTTGACT CTTCGAACTA TGACCCCTTC 
CGTCTGTGGC TGTGCGGCTC CCAGATGGTG GCACTCAATT TCCAGACTCC AGACAAATAC 
ATGCAGATGA ACCACGCGCT GTTTTCGCTC AATGGGCGAA CAGGCTACGT CCTGCAGCCT 
GAGAGCATGC GCTCTGAGAA GTATGATCCG ATGCCCCTGG AGTCCCAGAG GAAGATCCTG 
ATGACACTCA CTGTCAAGGT TCTTGGTGCA CGCCACCTCC CTAAACTAGG GCGGAGTATT 
GCCTGTCCTT TTGTGGAGGT GGAAATCTGC GGGGCTGAGT ATGACAGCAA CAAATTCAAG 
ACGACGGTTG TGAATGACAA TGGCCTCAGC CCTGTCTGGG CTCCAACTCA GGAGAAGGTG 
ACATTTGAGA TCTATGATCC AAACCTTGCC TTCCTACGCT TTGTGGTCTA CGAAGAAGAC 
ATGTTCAGTG ATCCCAACTT CCTGGCTCAT GCCACGTACC CCATTAAAGG CATCAAATCC 
GGGTTTAGAT CAGTCCCTCT GAAGAATGGG TACAGTGAAG ACATCGAGCT GGCATCCCTC 
CTGGTTTTCT GTGAGATGAG GCCAGTCCTG GAGAGTGAAG AGGAACTCTA TTCCTCCTGT 
CGCCAACTGC GGAGGCGGCA AGAAGAGCTC AACAACCAGC TCTTCCTTTA CGACACGCAC 
CAGAACCTGC GCGGAGCCAA CCGTGATGCC CTGGTGAAGG AGTTCAATGT TAACGAGAAT 
CAGCTGCAGC TGTACCAGGA GAAGTGCAAC CGGAGGCTGA GAGAGAAGAG AGTAAGCAAC 
AGCAGGTTCT ACTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Plcg2 ( NM_172285.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_758489.1 Mus musculus phospholipase C, gamma 2 (Plcg2), mRNA.

Price & Availability↑

CloneID	OMu83524
Clone ID Related Accession (Same CDS sequence)	NM_172285.2
Accession Version	NM_172285.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-22
Organism	Mus musculus(house mouse)
Product	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC161193.3 and AK142173.1. On Nov 26, 2015 this sequence version replaced NM_172285.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC023877.1, AK142173.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCACCA TGGTCAACGT GGACACCCTT CCAGAATATG AGAAGAGTCA GATCAAGAGA 
GCGCTGGAGT TAGGGACGGT GATGACCGTG TTCAACGCCC GCAAATCCAC CCCAGAGCGG 
AGGACAGTAC AGATGATCAT GGAGACTCGG CAGGTGGCAT GGAGCAAGAC CGCAGACAAG 
ATTGAAGGCT TCCTGGACAT CATGGAGATA AAGGAAATCC GTCCGGGGAA GAACTCCAAG 
GACTTTGAGC GAGCCAAGGC TGTCCGCCAC AAGGCAGAAT GTTGCTTCAC CATCCTCTAC 
GGCACCCAGT TTGTCCTCAG CACGCTCAGT TTGGCAACGG ACTCAAAGGA GGATGCGGTG 
AAGTGGCTCT CTGGTTTGAA GATCCTACAC CAGGAAGCGA TGAGTGCATC CACCCCCACA 
ATGATTGAGA GTTGGCTGAG AAAACAGATT TATTCAGTAG ATCAAACCCG AAGAAACAGC 
ATCAGCCTCC GGGAGCTGAA GACCATCTTG CCCCTGGTCA ACTTCAAAGT GAGCGGCATC 
AAGTTTCTCA AGGACAAGCT GGTGGAAATC GGCGCACAGA AAGATGAGCT CAGCTTTGAA 
CAGTTCCATC TCTTCTATAA GAAACTCATG TTTGACCAGC AAAAATCGAT ACTTGACGAA 
TTCAAAAAAG ACTCCTCCGT GTTCATCCTA GGAAACACAG ACCGGCCGGA TGCCTCGGCT 
GTCTACCTGC AGGACTTCCA AAGGTTTCTT TTACATGAAC AGCAGGAGCT ATGGGCTCAG 
GATCTGAACA AAGTCCGGGA GCGGATGACC AAGTTTATCG ACGACACAAT GAGAGAGACC 
GCAGAGCCCT TCTTATTTGT GGATGAGTTC CTCACGTATC TGTTCTCCCG GGAGAACAGC 
ATCTGGGACG AGAAGTACGA TGCAGTGGAC ATGCAGGACA TGAACAACCC CTTGTCCCAC 
TACTGGATCT CCTCTTCCCA CAACACGTAC CTCACTGGGG ACCAGCTGCG TAGTGAGTCC 
TCCACGGAAG CGTATATCCG CTGTCTGCGC GCTGGTTGCC GCTGCATTGA GCTGGACTGC 
TGGGACGGGC CTGATGGGAA GCCCATTATC TACCACGGCT GGACACGGAC CACCAAGATC 
AAGTTTGATG ATGTTGTTCA GGCCATCCGA GACCACGCCT TTGTTACCTC CAGCTTCCCC 
GTCATCTTGT CTATCGAGGA GCACTGCAGT GTGGAGCAGC AACGTCACAT GGCCAAGGTG 
TTCAAGGAAG TGTTAGGAGA CATGCTGTTG ACGAAGCCCA CAGAGGCCAG TGCTGACCAG 
CTGCCCTCGC CCAGTCAGCT TCGTGAGAAG ATCATTATCA AGCATAAGAA GCTGGGTCCC 
AAGGGTGATG TCGACGTCAA CGTGGAGGAC AAGAAAGATG AGCACAAGCC CCAGGGCGAG 
CTGTATATGT GGGACTCCAT CGACCAGAAA TGGACGCGCC ACTACTGTGC CATTGCTGAC 
GCCAAGCTGT CCTTCGGTGA TGACATTGAA CAGGCTGTGG AGGAGGAGCC GGTCCAGGAC 
ACTCCCCCCA CGGAGCTGCA TTTTGGGGAG AAATGGTTCC ACAAGAAGGT GGAGAGTAGG 
ACCAGTGCGG AGAAGCTGCT GCAAGAGTAC TGTGCTGAGA CCGGGGCCAA GGACGGCACC 
TTCCTGGTGC GGGAGAGCGA GACCTTCCCC AATGACTACA CACTCTCCTT CTGGCGGTCT 
GGCCGGGTGC AGCACTGCCG GATCCGGTCT ACTATGGAGA ATGGGGTCAT GAAGTACTAC 
CTGACCGACA ACCTCACGTT CAACAGCATC TACGCCCTCA TCCAGCACTA CCGTGAGGCA 
CACCTGCGCT GCGCGGAGTT CGAGCTGCGG CTCACAGACC CGGTGCCCAA CCCCAACCCA 
CACGAGTCCA AGCCGTGGTA CTATGACAGT CTGAGCAGGG GGGAAGCGGA GGACATGCTG 
ATGCGGATCC CCCGAGATGG AGCCTTCCTC ATCCGGAAGA GGGAGGGGAC CAACTCCTAC 
GCCATCACCT TCAGGGCCAG GGGCAAGGTG AAACATTGTC GCATCAACCG GGACGGACGC 
CACTTCGTGC TGGGCACCTC TGCCTACTTT GAGAGCCTGG TGGAGCTTGT CAGCTACTAC 
GAGAAGCACG CGCTCTATCG CAAGATGAGG CTTCGATACC CCGTGACCCC GGAGCTCCTG 
GAGCGATATA ATATGGAAAG AGACATCAAC TCTCTTTATG ACGTCAGCAG GATGTATGTG 
GACCCAAGTG AGATCAACCC TTCCATGCCT CAGAGGACCG TGAAAGCGCT CTATGACTAC 
AAAGCCAAGC GCAGCGACGA GCTGACCTTC TGCCGCGGTG CCCTCATCCA CAATGTCTCC 
AAGGAGCCCG GGGGATGGTG GAAAGGGGAC TACGGGACCC GGATCCAGCA GTACTTCCCG 
TCCAACTATG TCGAGGATAT CTCGGCAGGC GATGCTGAGG AGATGGAAAA GCAGATTATT 
GAAGACAATC CCCTCGGGTC TCTCTGCAAA GGCATATTGG ATCTTAATAC CTACAACGTT 
GTGAAGGCCC CCCAGGGGAA AAACCAGAAA GCCTTCGTCT TTATCCTGGA GCCTAAGAAA 
CAGGGAGATC CTCCCGTGGA GTTCGCGACC GACCGTGTGG AGGAGCTGTT TGAGTGGTTT 
CAGAGCATAC GGGAGATCAC TTGGAAGATG GACACCAAGG AGAACAACAT GAAGTACTGG 
GAGAGGAACC AGTCCATCGC CATTGAGCTC TCGGACTTGG TTGTATACTG CAAGCCAACT 
AGCAAAACCA AGGACCATTT GGAAAATCCC GACTTCCGAG AAATCCGCTC TTTTGTGGAG 
ACGAAGGCAG ACAGCATTGT CAGGCAAAAA CCTGTCGATC TATTGCGATA CAATCAGAAG 
GGCCTGACCC GAGTCTACCC CAAGGGACAG AGAGTTGACT CTTCGAACTA TGACCCCTTC 
CGTCTGTGGC TGTGCGGCTC CCAGATGGTG GCACTCAATT TCCAGACTCC AGACAAATAC 
ATGCAGATGA ACCACGCGCT GTTTTCGCTC AATGGGCGAA CAGGCTACGT CCTGCAGCCT 
GAGAGCATGC GCTCTGAGAA GTATGATCCG ATGCCCCTGG AGTCCCAGAG GAAGATCCTG 
ATGACACTCA CTGTCAAGGT TCTTGGTGCA CGCCACCTCC CTAAACTAGG GCGGAGTATT 
GCCTGTCCTT TTGTGGAGGT GGAAATCTGC GGGGCTGAGT ATGACAGCAA CAAATTCAAG 
ACGACGGTTG TGAATGACAA TGGCCTCAGC CCTGTCTGGG CTCCAACTCA GGAGAAGGTG 
ACATTTGAGA TCTATGATCC AAACCTTGCC TTCCTACGCT TTGTGGTCTA CGAAGAAGAC 
ATGTTCAGTG ATCCCAACTT CCTGGCTCAT GCCACGTACC CCATTAAAGG CATCAAATCC 
GGGTTTAGAT CAGTCCCTCT GAAGAATGGG TACAGTGAAG ACATCGAGCT GGCATCCCTC 
CTGGTTTTCT GTGAGATGAG GCCAGTCCTG GAGAGTGAAG AGGAACTCTA TTCCTCCTGT 
CGCCAACTGC GGAGGCGGCA AGAAGAGCTC AACAACCAGC TCTTCCTTTA CGACACGCAC 
CAGAACCTGC GCGGAGCCAA CCGTGATGCC CTGGTGAAGG AGTTCAATGT TAACGAGAAT 
CAGCTGCAGC TGTACCAGGA GAAGTGCAAC CGGAGGCTGA GAGAGAAGAG AGTAAGCAAC 
AGCAGGTTCT ACTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_758489.1
CDS	202..3999
Translation	MTTMVNVDTLPEYEKSQIKRALELGTVMTVFNARKSTPERRTVQMIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAKAVRHKAECCFTILYGTQFVLSTLSLATDSKEDAVKWLSGLKILHQEAMSASTPTMIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSGIKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFDQQKSILDEFKKDSSVFILGNTDRPDASAVYLQDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMAKVFKEVLGDMLLTKPTEASADQLPSPSQLREKIIIKHKKLGPKGDVDVNVEDKKDEHKPQGELYMWDSIDQKWTRHYCAIADAKLSFGDDIEQAVEEEPVQDTPPTELHFGEKWFHKKVESRTSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMENGVMKYYLTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGTNSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQIIEDNPLGSLCKGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFEWFQSIREITWKMDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSFVETKADSIVRQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPLESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLQLYQEKCNRRLREKRVSNSRFYS

Target ORF information:

RefSeq Version	NM_172285.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus phospholipase C, gamma 2 (Plcg2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172285.2

ORF Insert Sequence:

ATGACCACCA TGGTCAACGT GGACACCCTT CCAGAATATG AGAAGAGTCA GATCAAGAGA 
GCGCTGGAGT TAGGGACGGT GATGACCGTG TTCAACGCCC GCAAATCCAC CCCAGAGCGG 
AGGACAGTAC AGATGATCAT GGAGACTCGG CAGGTGGCAT GGAGCAAGAC CGCAGACAAG 
ATTGAAGGCT TCCTGGACAT CATGGAGATA AAGGAAATCC GTCCGGGGAA GAACTCCAAG 
GACTTTGAGC GAGCCAAGGC TGTCCGCCAC AAGGCAGAAT GTTGCTTCAC CATCCTCTAC 
GGCACCCAGT TTGTCCTCAG CACGCTCAGT TTGGCAACGG ACTCAAAGGA GGATGCGGTG 
AAGTGGCTCT CTGGTTTGAA GATCCTACAC CAGGAAGCGA TGAGTGCATC CACCCCCACA 
ATGATTGAGA GTTGGCTGAG AAAACAGATT TATTCAGTAG ATCAAACCCG AAGAAACAGC 
ATCAGCCTCC GGGAGCTGAA GACCATCTTG CCCCTGGTCA ACTTCAAAGT GAGCGGCATC 
AAGTTTCTCA AGGACAAGCT GGTGGAAATC GGCGCACAGA AAGATGAGCT CAGCTTTGAA 
CAGTTCCATC TCTTCTATAA GAAACTCATG TTTGACCAGC AAAAATCGAT ACTTGACGAA 
TTCAAAAAAG ACTCCTCCGT GTTCATCCTA GGAAACACAG ACCGGCCGGA TGCCTCGGCT 
GTCTACCTGC AGGACTTCCA AAGGTTTCTT TTACATGAAC AGCAGGAGCT ATGGGCTCAG 
GATCTGAACA AAGTCCGGGA GCGGATGACC AAGTTTATCG ACGACACAAT GAGAGAGACC 
GCAGAGCCCT TCTTATTTGT GGATGAGTTC CTCACGTATC TGTTCTCCCG GGAGAACAGC 
ATCTGGGACG AGAAGTACGA TGCAGTGGAC ATGCAGGACA TGAACAACCC CTTGTCCCAC 
TACTGGATCT CCTCTTCCCA CAACACGTAC CTCACTGGGG ACCAGCTGCG TAGTGAGTCC 
TCCACGGAAG CGTATATCCG CTGTCTGCGC GCTGGTTGCC GCTGCATTGA GCTGGACTGC 
TGGGACGGGC CTGATGGGAA GCCCATTATC TACCACGGCT GGACACGGAC CACCAAGATC 
AAGTTTGATG ATGTTGTTCA GGCCATCCGA GACCACGCCT TTGTTACCTC CAGCTTCCCC 
GTCATCTTGT CTATCGAGGA GCACTGCAGT GTGGAGCAGC AACGTCACAT GGCCAAGGTG 
TTCAAGGAAG TGTTAGGAGA CATGCTGTTG ACGAAGCCCA CAGAGGCCAG TGCTGACCAG 
CTGCCCTCGC CCAGTCAGCT TCGTGAGAAG ATCATTATCA AGCATAAGAA GCTGGGTCCC 
AAGGGTGATG TCGACGTCAA CGTGGAGGAC AAGAAAGATG AGCACAAGCC CCAGGGCGAG 
CTGTATATGT GGGACTCCAT CGACCAGAAA TGGACGCGCC ACTACTGTGC CATTGCTGAC 
GCCAAGCTGT CCTTCGGTGA TGACATTGAA CAGGCTGTGG AGGAGGAGCC GGTCCAGGAC 
ACTCCCCCCA CGGAGCTGCA TTTTGGGGAG AAATGGTTCC ACAAGAAGGT GGAGAGTAGG 
ACCAGTGCGG AGAAGCTGCT GCAAGAGTAC TGTGCTGAGA CCGGGGCCAA GGACGGCACC 
TTCCTGGTGC GGGAGAGCGA GACCTTCCCC AATGACTACA CACTCTCCTT CTGGCGGTCT 
GGCCGGGTGC AGCACTGCCG GATCCGGTCT ACTATGGAGA ATGGGGTCAT GAAGTACTAC 
CTGACCGACA ACCTCACGTT CAACAGCATC TACGCCCTCA TCCAGCACTA CCGTGAGGCA 
CACCTGCGCT GCGCGGAGTT CGAGCTGCGG CTCACAGACC CGGTGCCCAA CCCCAACCCA 
CACGAGTCCA AGCCGTGGTA CTATGACAGT CTGAGCAGGG GGGAAGCGGA GGACATGCTG 
ATGCGGATCC CCCGAGATGG AGCCTTCCTC ATCCGGAAGA GGGAGGGGAC CAACTCCTAC 
GCCATCACCT TCAGGGCCAG GGGCAAGGTG AAACATTGTC GCATCAACCG GGACGGACGC 
CACTTCGTGC TGGGCACCTC TGCCTACTTT GAGAGCCTGG TGGAGCTTGT CAGCTACTAC 
GAGAAGCACG CGCTCTATCG CAAGATGAGG CTTCGATACC CCGTGACCCC GGAGCTCCTG 
GAGCGATATA ATATGGAAAG AGACATCAAC TCTCTTTATG ACGTCAGCAG GATGTATGTG 
GACCCAAGTG AGATCAACCC TTCCATGCCT CAGAGGACCG TGAAAGCGCT CTATGACTAC 
AAAGCCAAGC GCAGCGACGA GCTGACCTTC TGCCGCGGTG CCCTCATCCA CAATGTCTCC 
AAGGAGCCCG GGGGATGGTG GAAAGGGGAC TACGGGACCC GGATCCAGCA GTACTTCCCG 
TCCAACTATG TCGAGGATAT CTCGGCAGGC GATGCTGAGG AGATGGAAAA GCAGATTATT 
GAAGACAATC CCCTCGGGTC TCTCTGCAAA GGCATATTGG ATCTTAATAC CTACAACGTT 
GTGAAGGCCC CCCAGGGGAA AAACCAGAAA GCCTTCGTCT TTATCCTGGA GCCTAAGAAA 
CAGGGAGATC CTCCCGTGGA GTTCGCGACC GACCGTGTGG AGGAGCTGTT TGAGTGGTTT 
CAGAGCATAC GGGAGATCAC TTGGAAGATG GACACCAAGG AGAACAACAT GAAGTACTGG 
GAGAGGAACC AGTCCATCGC CATTGAGCTC TCGGACTTGG TTGTATACTG CAAGCCAACT 
AGCAAAACCA AGGACCATTT GGAAAATCCC GACTTCCGAG AAATCCGCTC TTTTGTGGAG 
ACGAAGGCAG ACAGCATTGT CAGGCAAAAA CCTGTCGATC TATTGCGATA CAATCAGAAG 
GGCCTGACCC GAGTCTACCC CAAGGGACAG AGAGTTGACT CTTCGAACTA TGACCCCTTC 
CGTCTGTGGC TGTGCGGCTC CCAGATGGTG GCACTCAATT TCCAGACTCC AGACAAATAC 
ATGCAGATGA ACCACGCGCT GTTTTCGCTC AATGGGCGAA CAGGCTACGT CCTGCAGCCT 
GAGAGCATGC GCTCTGAGAA GTATGATCCG ATGCCCCTGG AGTCCCAGAG GAAGATCCTG 
ATGACACTCA CTGTCAAGGT TCTTGGTGCA CGCCACCTCC CTAAACTAGG GCGGAGTATT 
GCCTGTCCTT TTGTGGAGGT GGAAATCTGC GGGGCTGAGT ATGACAGCAA CAAATTCAAG 
ACGACGGTTG TGAATGACAA TGGCCTCAGC CCTGTCTGGG CTCCAACTCA GGAGAAGGTG 
ACATTTGAGA TCTATGATCC AAACCTTGCC TTCCTACGCT TTGTGGTCTA CGAAGAAGAC 
ATGTTCAGTG ATCCCAACTT CCTGGCTCAT GCCACGTACC CCATTAAAGG CATCAAATCC 
GGGTTTAGAT CAGTCCCTCT GAAGAATGGG TACAGTGAAG ACATCGAGCT GGCATCCCTC 
CTGGTTTTCT GTGAGATGAG GCCAGTCCTG GAGAGTGAAG AGGAACTCTA TTCCTCCTGT 
CGCCAACTGC GGAGGCGGCA AGAAGAGCTC AACAACCAGC TCTTCCTTTA CGACACGCAC 
CAGAACCTGC GCGGAGCCAA CCGTGATGCC CTGGTGAAGG AGTTCAATGT TAACGAGAAT 
CAGCTGCAGC TGTACCAGGA GAAGTGCAAC CGGAGGCTGA GAGAGAAGAG AGTAAGCAAC 
AGCAGGTTCT ACTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Spleen tyrosine kinase influences the early stages of multilineage differentiation of bone marrow stromal cell lines by regulating phospholipase C gamma activities.
Journal of cellular physiology233(3)2549-2559(2018 Mar)
Kusuyama J,Kamisono A,ChangHwan S,Amir MS,Bandow K,Eiraku N,Ohnishi T,Matsuguchi T

PLC?-dependent mTOR signalling controls IL-7-mediated early B cell development.
Nature communications8(1)1457(2017 Nov)
Yu M,Chen Y,Zeng H,Zheng Y,Fu G,Zhu W,Broeckel U,Aggarwal P,Turner A,Neale G,Guy C,Zhu N,Chi H,Wen R,Wang D

TULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of Syk.
The Journal of biological chemistry291(43)22427-22441(2016 Oct)
Reppschl?ger K,Gosselin J,Dangelmaier CA,Thomas DH,Carpino N,McKenzie SE,Kunapuli SP,Tsygankov AY

Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer.
The Journal of experimental medicine213(5)827-40(2016 May)
D'Amico L,Mahajan S,Capietto AH,Yang Z,Zamani A,Ricci B,Bumpass DB,Meyer M,Su X,Wang-Gillam A,Weilbaecher K,Stewart SA,DeNardo DG,Faccio R

Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo.
Nature communications711004(2016 Apr)
N?meth T,Futosi K,Sitaru C,Ruland J,M?csai A

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Plcg2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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