Nrn1l cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nrn1l
Entrez Gene ID	234700
Full Name	neuritin 1-like
Synonyms	Cpg15-2,G630049C14Rik
General protein information	Preferred Names neuritin 1-like Names neuritin-like protein MRCC2446-like protein candidate plasticity gene 15-2 protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 D3

mRNA and Protein(s)

mRNA	Protein	Name
NM_175024.4	NP_778189.1	neuritin-like protein isoform 1 precursor
NM_001301174.1	NP_001288103.1	neuritin-like protein isoform 2 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Nrn1l	NP_001128478.1
Homo sapiens (human)	NRN1L	NP_940845.1
Pan troglodytes (chimpanzee)	NRN1L	XP_003315203.1
Canis lupus familiaris (dog)	NRN1L	XP_005620864.1
Mus musculus (house mouse)	Nrn1l	NP_778189.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

cpg15 and cpg15-2 constitute a family of activity-regulated ligands expressed differentially in the nervous system to promote neurite growth and neuronal survival.
Fujino T, Wu Z, Lin WC, Phillips MA, Nedivi E
The Journal of comparative neurology507(5)1831-45(2008 Apr)

Genomic analysis of mouse retinal development.
Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL
PLoS biology2(9)E247(2004 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CPG15 and CPG15-2 perform similar cellular functions but may play distinct roles in vivo through their cell-type- and tissue-specific transcriptional regulation
Title: cpg15 and cpg15-2 constitute a family of activity-regulated ligands expressed differentially in the nervous system to promote neurite growth and neuronal survival.

The following Nrn1l gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nrn1l cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04781	NM_175024.4 Latest version!	Mus musculus neuritin 1-like (Nrn1l), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu73782	NM_001301174.1 Latest version!	Mus musculus neuritin 1-like (Nrn1l), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nrn1l ( NM_175024.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_778189.1 Mus musculus neuritin 1-like (Nrn1l), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu04781
Clone ID Related Accession (Same CDS sequence)	NM_175024.4
Accession Version	NM_175024.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Mus musculus(house mouse)
Product	neuritin-like protein isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC100315.1 and CK030777.1. On Jul 24, 2014 this sequence version replaced NM_175024.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC100315.1, CO808500.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGTGCA ACTGCTGCCA CTGCCACTGG CGCCGCCGCT GTCAGCGGCT ACCCTGTGCC 
CTGACGCTGT TGCTGCTACT ACCACTCGCA GTGGCCTCTG AGGGCCCAAA CCGCTGTGAT 
ACCATATACC AAGGCTTTGC TGAATGTCTC ATCCGCCTGG GGGATGGCAT GGGTCGAGGA 
GGCGAGCTAC AGACTGTCTG CAGATCCTGG AATGACTTCC ACGCCTGTGC CTCTCGGGTC 
CTGTCAGGCT GCCCAGAGGA GGCGGCTGCA GTGTGGGAGT CACTGCAGCA AGAAGCTCGC 
CGCGCCCCAC ACCCAGATAA TTTGCACATC CTCTGTGGCG CTCCTGTGAG TGTTCGGGAG 
CGGATTGCTG GCCCAGAGAC CAACCAGGAG ACACTACGGG CCACAGCTCC TGCACTGGCT 
CCAGCTCCAG CCCCTGTGTT GCTCGCCGCC GCTCTAGCGC TTGCCTGCCT CCTGGGGCCT 
CTGGCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_778189.1
CDS	14..502
Translation	MMCNCCHCHWRRRCQRLPCALTLLLLLPLAVASEGPNRCDTIYQGFAECLIRLGDGMGRGGELQTVCRSWNDFHACASRVLSGCPEEAAAVWESLQQEARRAPHPDNLHILCGAPVSVRERIAGPETNQETLRATAPALAPAPAPVLLAAALALACLLGPLA

Target ORF information:

RefSeq Version	NM_175024.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus neuritin 1-like (Nrn1l), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175024.4

ORF Insert Sequence:

ATGATGTGCA ACTGCTGCCA CTGCCACTGG CGCCGCCGCT GTCAGCGGCT ACCCTGTGCC 
CTGACGCTGT TGCTGCTACT ACCACTCGCA GTGGCCTCTG AGGGCCCAAA CCGCTGTGAT 
ACCATATACC AAGGCTTTGC TGAATGTCTC ATCCGCCTGG GGGATGGCAT GGGTCGAGGA 
GGCGAGCTAC AGACTGTCTG CAGATCCTGG AATGACTTCC ACGCCTGTGC CTCTCGGGTC 
CTGTCAGGCT GCCCAGAGGA GGCGGCTGCA GTGTGGGAGT CACTGCAGCA AGAAGCTCGC 
CGCGCCCCAC ACCCAGATAA TTTGCACATC CTCTGTGGCG CTCCTGTGAG TGTTCGGGAG 
CGGATTGCTG GCCCAGAGAC CAACCAGGAG ACACTACGGG CCACAGCTCC TGCACTGGCT 
CCAGCTCCAG CCCCTGTGTT GCTCGCCGCC GCTCTAGCGC TTGCCTGCCT CCTGGGGCCT 
CTGGCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nrn1l ( NM_001301174.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001288103.1 Mus musculus neuritin 1-like (Nrn1l), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu73782
Clone ID Related Accession (Same CDS sequence)	NM_001301174.1
Accession Version	NM_001301174.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 486bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Mus musculus(house mouse)
Product	neuritin-like protein isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC100315.1, AK080711.1 and CK030777.1. On Jul 24, 2014 this sequence version replaced XM_006530906.1. Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is 1 aa shorter compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK080711.1, BY742180.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGTGCA ACTGCTGCCA CTGCCACTGG CGCCGCCGCT GTCAGCGGCT ACCCTGTGCC 
CTGACGCTGT TGCTGCTACT ACCACTCGTG GCCTCTGAGG GCCCAAACCG CTGTGATACC 
ATATACCAAG GCTTTGCTGA ATGTCTCATC CGCCTGGGGG ATGGCATGGG TCGAGGAGGC 
GAGCTACAGA CTGTCTGCAG ATCCTGGAAT GACTTCCACG CCTGTGCCTC TCGGGTCCTG 
TCAGGCTGCC CAGAGGAGGC GGCTGCAGTG TGGGAGTCAC TGCAGCAAGA AGCTCGCCGC 
GCCCCACACC CAGATAATTT GCACATCCTC TGTGGCGCTC CTGTGAGTGT TCGGGAGCGG 
ATTGCTGGCC CAGAGACCAA CCAGGAGACA CTACGGGCCA CAGCTCCTGC ACTGGCTCCA 
GCTCCAGCCC CTGTGTTGCT CGCCGCCGCT CTAGCGCTTG CCTGCCTCCT GGGGCCTCTG 
GCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288103.1
CDS	14..499
Translation	MMCNCCHCHWRRRCQRLPCALTLLLLLPLVASEGPNRCDTIYQGFAECLIRLGDGMGRGGELQTVCRSWNDFHACASRVLSGCPEEAAAVWESLQQEARRAPHPDNLHILCGAPVSVRERIAGPETNQETLRATAPALAPAPAPVLLAAALALACLLGPLA

Target ORF information:

RefSeq Version	NM_001301174.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus neuritin 1-like (Nrn1l), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301174.1

ORF Insert Sequence:

ATGATGTGCA ACTGCTGCCA CTGCCACTGG CGCCGCCGCT GTCAGCGGCT ACCCTGTGCC 
CTGACGCTGT TGCTGCTACT ACCACTCGTG GCCTCTGAGG GCCCAAACCG CTGTGATACC 
ATATACCAAG GCTTTGCTGA ATGTCTCATC CGCCTGGGGG ATGGCATGGG TCGAGGAGGC 
GAGCTACAGA CTGTCTGCAG ATCCTGGAAT GACTTCCACG CCTGTGCCTC TCGGGTCCTG 
TCAGGCTGCC CAGAGGAGGC GGCTGCAGTG TGGGAGTCAC TGCAGCAAGA AGCTCGCCGC 
GCCCCACACC CAGATAATTT GCACATCCTC TGTGGCGCTC CTGTGAGTGT TCGGGAGCGG 
ATTGCTGGCC CAGAGACCAA CCAGGAGACA CTACGGGCCA CAGCTCCTGC ACTGGCTCCA 
GCTCCAGCCC CTGTGTTGCT CGCCGCCGCT CTAGCGCTTG CCTGCCTCCT GGGGCCTCTG 
GCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

cpg15 and cpg15-2 constitute a family of activity-regulated ligands expressed differentially in the nervous system to promote neurite growth and neuronal survival.
The Journal of comparative neurology507(5)1831-45(2008 Apr)
Fujino T,Wu Z,Lin WC,Phillips MA,Nedivi E

Genomic analysis of mouse retinal development.
PLoS biology2(9)E247(2004 Sep)
Blackshaw S,Harpavat S,Trimarchi J,Cai L,Huang H,Kuo WP,Weber G,Lee K,Fraioli RE,Cho SH,Yung R,Asch E,Ohno-Machado L,Wong WH,Cepko CL

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Nrn1l cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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