Gprc5a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gprc5a
Entrez Gene ID	232431
Full Name	G protein-coupled receptor, family C, group 5, member A
Synonyms	Rai3,Raig1
General protein information	Preferred Names G protein-coupled receptor, family C, group 5, member A Names retinoic acid-induced protein 3 RAIG-1 retinoic acid induced 3 retinoic acid-induced gene 1 protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 G1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006506038.2	XP_006506101.1	retinoic acid-induced protein 3 isoform X1
NM_181444.5	NP_852109.2	retinoic acid-induced protein 3

Pathways from BioSystems

Homologies

	GPRC5A	XP_001086713.1
Canis lupus familiaris (dog)	GPRC5A	XP_543807.2
Mus musculus (house mouse)	Gprc5a	NP_852109.2
Rattus norvegicus (Norway rat)	Gprc5a	NP_001073359.1
Homo sapiens (human)	GPRC5A	NP_003970.1
Xenopus tropicalis (tropical clawed frog)	gprc5a	XP_002934774.1
Pan troglodytes (chimpanzee)	GPRC5A	XP_001154830.1
Bos taurus (cattle)	GPRC5A	NP_001029687.1
Gallus gallus (chicken)	GPRC5A	XP_416200.2

Gene Ontology
Bibliography

Related articles in PubMed

Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a.
Fujimoto J, Nunomura-Nakamura S, Liu Y, Lang W, McDowell T, Jakubek Y, Ezzeddine D, Kapere Ochieng J, Petersen J, Davies G, Fukuoka J, Wistuba II, Ehli E, Fowler J, Scheet P, Kadara H
International journal of cancer141(8)1589-1599(2017 Oct)

Gpr158 mediates osteocalcin's regulation of cognition.
Khrimian L, Obri A, Ramos-Brossier M, Rousseaud A, Moriceau S, Nicot AS, Mera P, Kosmidis S, Karnavas T, Saudou F, Gao XB, Oury F, Kandel E, Karsenty G
The Journal of experimental medicine214(10)2859-2873(2017 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study underscores genomic alterations that represent early events in the development of Kras mutant LUAD following Gprc5a loss and tobacco carcinogen exposure.
Title: Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a.

Data show that G protein-coupled receptor, family C, group 5, member A protein (Gprc5a) deficiency exacerbates the silica-induced tissue damages and fibrogenic response in lungs.
Title: Epithelial neoplasia coincides with exacerbated injury and fibrotic response in the lungs of Gprc5a-knockout mice following silica exposure.

Gprc5a deficiency leads to impaired induction of peripherally derived regulatory T-cells and increased experimental autoimmune encephalomyelitis severity.
Title: MicroRNA-31 negatively regulates peripherally derived regulatory T-cell generation by repressing retinoic acid-inducible protein 3.

Results show how GPRC5A deficiency leads to dysregulated EGFR and STAT3 signaling and lung tumorigenesis.
Title: Lung Tumor Suppressor GPRC5A Binds EGFR and Restrains Its Effector Signaling.

Gprc5a deficiency confers susceptibility to endotoxin-induced pulmonary edema and injury, mainly through NF-kappaB signaling in bronchioalveolar epithelium of lung.
Title: Gprc5a-deficiency confers susceptibility to endotoxin-induced acute lung injury via NF-?B pathway.

The following Gprc5a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gprc5a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu08061	NM_181444.5 Latest version!	Mus musculus G protein-coupled receptor, family C, group 5, member A (Gprc5a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OMu08061	XM_006506038.2 Latest version!	Mus musculus G protein-coupled receptor, family C, group 5, member A (Gprc5a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gprc5a ( NM_181444.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_852109.2 Mus musculus G protein-coupled receptor, family C, group 5, member A (Gprc5a), mRNA.

Price & Availability↑

CloneID	OMu08061
Clone ID Related Accession (Same CDS sequence)	XM_006506038.2 , NM_181444.5
Accession Version	NM_181444.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1071bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-15
Organism	Mus musculus(house mouse)
Product	retinoic acid-induced protein 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC140287.3. On Mar 21, 2009 this sequence version replaced NM_181444.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC039217.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849376, SAMN00849377 [ECO:0000348] ##Evidence-Data-END##

ATGACTACTC CTAGAGCTGC CCCTAGCGGT TGCCGCTCAG ACCTGGATTC CAGGTACCAC 
AGACTTTGTG ACCTGGCGGA AGGCTGGGGC ATCGCGTTGG AAACACTGGC TGCCGTCGGG 
GCTGTGGCTA CCGTGGCTTG CATGTTTGCA CTCGTTTTCC TCATCTGCAA AGTGCAGGAC 
TCCAACAAAA GAAAGATGCT CCCCGCCCAG TTCCTCTTCC TCCTGGGAGT GCTAGGGGTC 
TTTGGCCTCA CCTTCGCCTT CATCATCAAG CTGGATGGGG CCACAGGACC CACGCGCTTC 
TTCCTCTTCG GAGTCCTCTT CGCCATCTGC TTCTCTTGCC TCCTGGCCCA CGCTTTCAAC 
TTGATCAAGC TGGTCCGAGG GAGGAAGCCC CTGTCGTGGC TTGTGATCCT CAGCCTGGCG 
GTGGGCTTCA GCCTGGTCCA GGACGTCATT GCCATTGAAT ACCTGGTCCT CACCATGAAC 
AGGACCAACG TCAATGTCTT TTCTGAGCTG CCTGCTCCTC GGCGCAATGA GGATTTCGTC 
ATGCTCCTCA TTTACGTGCT CGTCTTGATG GTGCTGACCT TCTTCGCATC CTTCTTGGTT 
TTCTGTGGAT CCTTCTCTGG CTGGAAGAGA CACGGGTTCC ACATATGCTT CACCTCGTTC 
CTCTCCATTG CCATCTGGGT GGCCTGGATC GTTCTGCTCC TGATTCCCGA CATTGACCGG 
AAATGGGATG ATACCATTCT CAGCACAGCC TTGGTGGCCA ACGGCTGGGT TTTCCTGGCG 
TTTTATATCT TGCCCGAGTT TCGACAGCTC CCAAGGCAAC GGAGCCCCAC TGATTACCCA 
GTTGAAGATG CTTTTTGTAA ACCTCAGCTC ATGAAGCAGA GCTATGGTGT GGAGAACAGA 
GCCTACTCCC AAGAGGAAAT CACCCAAGGT CTTGAGATGG GGGACACACT CTATGCACCT 
TATTCCACCC ATTTTCAGCT ACAGAATCAC CAAAAGGATT TCTCTATCCC GAGGGCCCAG 
GCCCCGGCCA GTCCGTACAA TGACTACGAA GGGCGCAAAG GCGACAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_852109.2
CDS	126..1196
Translation	MTTPRAAPSGCRSDLDSRYHRLCDLAEGWGIALETLAAVGAVATVACMFALVFLICKVQDSNKRKMLPAQFLFLLGVLGVFGLTFAFIIKLDGATGPTRFFLFGVLFAICFSCLLAHAFNLIKLVRGRKPLSWLVILSLAVGFSLVQDVIAIEYLVLTMNRTNVNVFSELPAPRRNEDFVMLLIYVLVLMVLTFFASFLVFCGSFSGWKRHGFHICFTSFLSIAIWVAWIVLLLIPDIDRKWDDTILSTALVANGWVFLAFYILPEFRQLPRQRSPTDYPVEDAFCKPQLMKQSYGVENRAYSQEEITQGLEMGDTLYAPYSTHFQLQNHQKDFSIPRAQAPASPYNDYEGRKGDS

Target ORF information:

RefSeq Version	NM_181444.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus G protein-coupled receptor, family C, group 5, member A (Gprc5a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181444.5

ORF Insert Sequence:

ATGACTACTC CTAGAGCTGC CCCTAGCGGT TGCCGCTCAG ACCTGGATTC CAGGTACCAC 
AGACTTTGTG ACCTGGCGGA AGGCTGGGGC ATCGCGTTGG AAACACTGGC TGCCGTCGGG 
GCTGTGGCTA CCGTGGCTTG CATGTTTGCA CTCGTTTTCC TCATCTGCAA AGTGCAGGAC 
TCCAACAAAA GAAAGATGCT CCCCGCCCAG TTCCTCTTCC TCCTGGGAGT GCTAGGGGTC 
TTTGGCCTCA CCTTCGCCTT CATCATCAAG CTGGATGGGG CCACAGGACC CACGCGCTTC 
TTCCTCTTCG GAGTCCTCTT CGCCATCTGC TTCTCTTGCC TCCTGGCCCA CGCTTTCAAC 
TTGATCAAGC TGGTCCGAGG GAGGAAGCCC CTGTCGTGGC TTGTGATCCT CAGCCTGGCG 
GTGGGCTTCA GCCTGGTCCA GGACGTCATT GCCATTGAAT ACCTGGTCCT CACCATGAAC 
AGGACCAACG TCAATGTCTT TTCTGAGCTG CCTGCTCCTC GGCGCAATGA GGATTTCGTC 
ATGCTCCTCA TTTACGTGCT CGTCTTGATG GTGCTGACCT TCTTCGCATC CTTCTTGGTT 
TTCTGTGGAT CCTTCTCTGG CTGGAAGAGA CACGGGTTCC ACATATGCTT CACCTCGTTC 
CTCTCCATTG CCATCTGGGT GGCCTGGATC GTTCTGCTCC TGATTCCCGA CATTGACCGG 
AAATGGGATG ATACCATTCT CAGCACAGCC TTGGTGGCCA ACGGCTGGGT TTTCCTGGCG 
TTTTATATCT TGCCCGAGTT TCGACAGCTC CCAAGGCAAC GGAGCCCCAC TGATTACCCA 
GTTGAAGATG CTTTTTGTAA ACCTCAGCTC ATGAAGCAGA GCTATGGTGT GGAGAACAGA 
GCCTACTCCC AAGAGGAAAT CACCCAAGGT CTTGAGATGG GGGACACACT CTATGCACCT 
TATTCCACCC ATTTTCAGCT ACAGAATCAC CAAAAGGATT TCTCTATCCC GAGGGCCCAG 
GCCCCGGCCA GTCCGTACAA TGACTACGAA GGGCGCAAAG GCGACAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gprc5a ( XM_006506038.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006506101.1 Mus musculus G protein-coupled receptor, family C, group 5, member A (Gprc5a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu08061
Clone ID Related Accession (Same CDS sequence)	XM_006506038.2 , NM_181444.5
Accession Version	XM_006506038.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1071bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	retinoic acid-induced protein 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006506038.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTACTC CTAGAGCTGC CCCTAGCGGT TGCCGCTCAG ACCTGGATTC CAGGTACCAC 
AGACTTTGTG ACCTGGCGGA AGGCTGGGGC ATCGCGTTGG AAACACTGGC TGCCGTCGGG 
GCTGTGGCTA CCGTGGCTTG CATGTTTGCA CTCGTTTTCC TCATCTGCAA AGTGCAGGAC 
TCCAACAAAA GAAAGATGCT CCCCGCCCAG TTCCTCTTCC TCCTGGGAGT GCTAGGGGTC 
TTTGGCCTCA CCTTCGCCTT CATCATCAAG CTGGATGGGG CCACAGGACC CACGCGCTTC 
TTCCTCTTCG GAGTCCTCTT CGCCATCTGC TTCTCTTGCC TCCTGGCCCA CGCTTTCAAC 
TTGATCAAGC TGGTCCGAGG GAGGAAGCCC CTGTCGTGGC TTGTGATCCT CAGCCTGGCG 
GTGGGCTTCA GCCTGGTCCA GGACGTCATT GCCATTGAAT ACCTGGTCCT CACCATGAAC 
AGGACCAACG TCAATGTCTT TTCTGAGCTG CCTGCTCCTC GGCGCAATGA GGATTTCGTC 
ATGCTCCTCA TTTACGTGCT CGTCTTGATG GTGCTGACCT TCTTCGCATC CTTCTTGGTT 
TTCTGTGGAT CCTTCTCTGG CTGGAAGAGA CACGGGTTCC ACATATGCTT CACCTCGTTC 
CTCTCCATTG CCATCTGGGT GGCCTGGATC GTTCTGCTCC TGATTCCCGA CATTGACCGG 
AAATGGGATG ATACCATTCT CAGCACAGCC TTGGTGGCCA ACGGCTGGGT TTTCCTGGCG 
TTTTATATCT TGCCCGAGTT TCGACAGCTC CCAAGGCAAC GGAGCCCCAC TGATTACCCA 
GTTGAAGATG CTTTTTGTAA ACCTCAGCTC ATGAAGCAGA GCTATGGTGT GGAGAACAGA 
GCCTACTCCC AAGAGGAAAT CACCCAAGGT CTTGAGATGG GGGACACACT CTATGCACCT 
TATTCCACCC ATTTTCAGCT ACAGAATCAC CAAAAGGATT TCTCTATCCC GAGGGCCCAG 
GCCCCGGCCA GTCCGTACAA TGACTACGAA GGGCGCAAAG GCGACAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006506101.1
CDS	159..1229
Translation	MTTPRAAPSGCRSDLDSRYHRLCDLAEGWGIALETLAAVGAVATVACMFALVFLICKVQDSNKRKMLPAQFLFLLGVLGVFGLTFAFIIKLDGATGPTRFFLFGVLFAICFSCLLAHAFNLIKLVRGRKPLSWLVILSLAVGFSLVQDVIAIEYLVLTMNRTNVNVFSELPAPRRNEDFVMLLIYVLVLMVLTFFASFLVFCGSFSGWKRHGFHICFTSFLSIAIWVAWIVLLLIPDIDRKWDDTILSTALVANGWVFLAFYILPEFRQLPRQRSPTDYPVEDAFCKPQLMKQSYGVENRAYSQEEITQGLEMGDTLYAPYSTHFQLQNHQKDFSIPRAQAPASPYNDYEGRKGDS

Target ORF information:

RefSeq Version	XM_006506038.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus G protein-coupled receptor, family C, group 5, member A (Gprc5a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006506038.2

ORF Insert Sequence:

ATGACTACTC CTAGAGCTGC CCCTAGCGGT TGCCGCTCAG ACCTGGATTC CAGGTACCAC 
AGACTTTGTG ACCTGGCGGA AGGCTGGGGC ATCGCGTTGG AAACACTGGC TGCCGTCGGG 
GCTGTGGCTA CCGTGGCTTG CATGTTTGCA CTCGTTTTCC TCATCTGCAA AGTGCAGGAC 
TCCAACAAAA GAAAGATGCT CCCCGCCCAG TTCCTCTTCC TCCTGGGAGT GCTAGGGGTC 
TTTGGCCTCA CCTTCGCCTT CATCATCAAG CTGGATGGGG CCACAGGACC CACGCGCTTC 
TTCCTCTTCG GAGTCCTCTT CGCCATCTGC TTCTCTTGCC TCCTGGCCCA CGCTTTCAAC 
TTGATCAAGC TGGTCCGAGG GAGGAAGCCC CTGTCGTGGC TTGTGATCCT CAGCCTGGCG 
GTGGGCTTCA GCCTGGTCCA GGACGTCATT GCCATTGAAT ACCTGGTCCT CACCATGAAC 
AGGACCAACG TCAATGTCTT TTCTGAGCTG CCTGCTCCTC GGCGCAATGA GGATTTCGTC 
ATGCTCCTCA TTTACGTGCT CGTCTTGATG GTGCTGACCT TCTTCGCATC CTTCTTGGTT 
TTCTGTGGAT CCTTCTCTGG CTGGAAGAGA CACGGGTTCC ACATATGCTT CACCTCGTTC 
CTCTCCATTG CCATCTGGGT GGCCTGGATC GTTCTGCTCC TGATTCCCGA CATTGACCGG 
AAATGGGATG ATACCATTCT CAGCACAGCC TTGGTGGCCA ACGGCTGGGT TTTCCTGGCG 
TTTTATATCT TGCCCGAGTT TCGACAGCTC CCAAGGCAAC GGAGCCCCAC TGATTACCCA 
GTTGAAGATG CTTTTTGTAA ACCTCAGCTC ATGAAGCAGA GCTATGGTGT GGAGAACAGA 
GCCTACTCCC AAGAGGAAAT CACCCAAGGT CTTGAGATGG GGGACACACT CTATGCACCT 
TATTCCACCC ATTTTCAGCT ACAGAATCAC CAAAAGGATT TCTCTATCCC GAGGGCCCAG 
GCCCCGGCCA GTCCGTACAA TGACTACGAA GGGCGCAAAG GCGACAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a.
International journal of cancer141(8)1589-1599(2017 Oct)
Fujimoto J,Nunomura-Nakamura S,Liu Y,Lang W,McDowell T,Jakubek Y,Ezzeddine D,Kapere Ochieng J,Petersen J,Davies G,Fukuoka J,Wistuba II,Ehli E,Fowler J,Scheet P,Kadara H

Gpr158 mediates osteocalcin's regulation of cognition.
The Journal of experimental medicine214(10)2859-2873(2017 Oct)
Khrimian L,Obri A,Ramos-Brossier M,Rousseaud A,Moriceau S,Nicot AS,Mera P,Kosmidis S,Karnavas T,Saudou F,Gao XB,Oury F,Kandel E,Karsenty G

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Gprc5a cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報