Kdm4a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kdm4a
Entrez Gene ID	230674
Full Name	lysine (K)-specific demethylase 4A
Synonyms	D4Ertd222e,JHDM3A,Jmjd2,Jmjd2a,mKIAA0677
General protein information	Preferred Names lysine (K)-specific demethylase 4A Names lysine-specific demethylase 4A jmjC domain-containing histone demethylation protein 3A jumonji domain containing 2A jumonji domain-containing protein 2A
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4 D2.1\|4 54.31 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006503011.3	XP_006503074.1	lysine-specific demethylase 4A isoform X2
XM_006503010.2	XP_006503073.1	lysine-specific demethylase 4A isoform X1
NM_172382.2	NP_759014.2	lysine-specific demethylase 4A isoform 2
NM_001161823.1	NP_001155295.1	lysine-specific demethylase 4A isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	KDM4A	XP_513384.3
Canis lupus familiaris (dog)	KDM4A	XP_005629165.1
Rattus norvegicus (Norway rat)	Kdm4a	NP_001101436.1
Danio rerio (zebrafish)	si:ch211-215f22.3	XP_005165745.1
Caenorhabditis elegans (roundworm)	jmjd-2	NP_496969.2
Homo sapiens (human)	KDM4A	NP_055478.2
	KDM4A	XP_001096047.2
Bos taurus (cattle)	KDM4A	NP_001193245.1
Mus musculus (house mouse)	Kdm4a	NP_001155295.1
Xenopus tropicalis (tropical clawed frog)	kdm4a	NP_001107498.1
Gallus gallus (chicken)	KDM4A	XP_422410.3

Gene Ontology
Bibliography

Related articles in PubMed

The histone demethylase JMJD2A regulates the expression of BDNF and mediates neuropathic pain in mice.
Zhou J, Wang F, Xu C, Zhou Z, Zhang W
Experimental cell research361(1)155-162(2017 12)

Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin.
Matsuura T, Miyazaki S, Miyazaki T, Tashiro F, Miyazaki JI
Scientific reports7(1)12462(2017 Sep)

Maternal expression of the histone demethylase Kdm4a is crucial for pre-implantation development.
Sankar A, Kooistra SM, Gonzalez JM, Ohlsson C, Poutanen M, Helin K
Development (Cambridge, England)144(18)3264-3277(2017 09)

Inhibition of KDM4A activity as a strategy to suppress interleukin-6 production and attenuate colitis induction.
Ishiguro K, Watanabe O, Nakamura M, Yamamura T, Matsushita M, Goto H, Hirooka Y
Clinical immunology (Orlando, Fla.)180120-127(2017 Jul)

Histone Lysine Demethylases of JMJD2 or KDM4 Family are Important Epigenetic Regulators in Reward Circuitry in the Etiopathology of Depression.
Pathak SS, Maitra S, Chakravarty S, Kumar A
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology42(4)854-863(2017 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

High Jmjd2a expression is associated with neuropathic pain.
Title: The histone demethylase JMJD2A regulates the expression of BDNF and mediates neuropathic pain in mice.

This study dissects an important dual role for maternal Kdm4a in determining faithful early embryonic development and the implantation process.
Title: Maternal expression of the histone demethylase Kdm4a is crucial for pre-implantation development.

We propose the inhibition of KDM4A activity as a strategy to suppress IL-6 production and attenuate colitis induction.
Title: Inhibition of KDM4A activity as a strategy to suppress interleukin-6 production and attenuate colitis induction.

Jmjd2 class demethylases are critical epigenetic regulators involved in etiopathology of depression and related disorders.
Title: Histone Lysine Demethylases of JMJD2 or KDM4 Family are Important Epigenetic Regulators in Reward Circuitry in the Etiopathology of Depression.

The authors show that Jmjd2a and Jmjd2c both localize to H3K4me3-positive promoters, where they have widespread and redundant roles in preventing accumulation of H3K9me3 and H3K36me3.
Title: Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development.

The following Kdm4a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kdm4a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu33535	XM_006503011.3 Latest version!	Mus musculus lysine (K)-specific demethylase 4A (Kdm4a), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu13617	NM_172382.2 Latest version!	Mus musculus lysine (K)-specific demethylase 4A (Kdm4a), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OMu14006	NM_001161823.1 Latest version!	Mus musculus lysine (K)-specific demethylase 4A (Kdm4a), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OMu14006	XM_006503010.2 Latest version!	Mus musculus lysine (K)-specific demethylase 4A (Kdm4a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kdm4a ( XM_006503011.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006503074.1 Mus musculus lysine (K)-specific demethylase 4A (Kdm4a), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu33535
Clone ID Related Accession (Same CDS sequence)	XM_006503011.3
Accession Version	XM_006503011.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1893bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	lysine-specific demethylase 4A isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006503011.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCTG AATCAGAAAC TTTGAACCCC AGTGCTCGGA TCATGACCTT TTACCCCACC 
ATGGAAGAGT TCCGGAACTT CAGCCGCTAC ATTGCCTACA TTGAATCCCA AGGAGCTCAT 
CGGGCTGGGC TAGCCAAGGT CGTTCCTCCC AAAGAGTGGA AGCCTCGAAC ATCCTACGAC 
GATATTGATG ATCTAGTCAT CCCTGCGCCC ATCCAGCAGC TGGTGACTGG CCAGTCTGGC 
CTCTTCACTC AGTACAACAT ACAGAAGAAA GCCATGACCG TTCGTGAGTT CCGCAAGATC 
GCCAATAGCG ACAAGTACTG CACCCCGCGA TACAGTGAAT TTGAAGAACT TGAGCGTAAA 
TACTGGAAAA ACCTCACATT CAATCCTCCC ATCTATGGAG CAGACGTGAA TGGTACTCTC 
TATGAACAGC ACGTTGATGA GTGGAATATC GGCCGGCTGA AGACCATCCT GGACCTGGTG 
GAGAAGGAGA GCGGGATCAC CATTGAGGGG GTGAACACCC CCTACCTTTA CTTCGGCATG 
TGGAAGACGT CCTTCGCCTG GCACACGGAA GACATGGATC TATACAGCAT CAACTATCTG 
CACTTCGGAG AGCCAAAGTC TTGGTACTCT GTTCCACCTG AGCATGGGAA ACGCCTGGAG 
CGTCTTGCCA AAGGCTTTTT CCCAGGAAGT GCTCAAAGCT GTGAGGCTTT TCTCCGCCAC 
AAGATGACCC TGATCTCCCC ATTAATGCTG AAGAAGTATG GCATTCCCTT TGACAAGGTG 
ACCCAAGAAG CTGGCGAGTT TATGATCACT TTTCCGTATG GTTACCATGC TGGCTTCAAC 
CATGGCTTCA ACTGTGCAGA GTCAACCAAT TTTGCTACCC GTCGGTGGAT TGAGTATGGC 
AAGCAGGCTG TGCTGTGCTC CTGCAGAAAA GATATGGTGA AGATCTCCAT GGACGTGTTC 
GTGAGGAGGT TCCAGCCGGA ACGCTACAAA CTTTGGAAAG CTGGGAAGGA CAGCATGGTT 
ATTGACCACA CTCTGCCCAC ACCGGAAGCA GCCGAGTTCC TGAAGGACAG CGGCGGACTA 
ACCCCGAGAG CAGGGAGTGA GGAGTGCCCA GAGGAGGACG TGGAAGCAGC GGATCAGGGA 
GAGGAGGGGG ATGTGAAGAG AAGCCTGGCC AAGCATCGGA TCGGGACAAA GAGACACAGA 
GTCTGTCTGG AAATACCCCA GGAGGTCAGT CAGAGCGAGC TCTTCCCCAA GGAAGAGCTA 
AGTTCTGGAC AGTATGAGAT GACAGAGTGC CCGGCCACCC TCGCCCCAGT GAGGCCCACC 
CACAGCTCCG TGCGGCAAGT TGAGGACAGT CTTCCCTTCC CAGATTACTC TGACCCCACT 
GAAGTCAAAT TTGAAGAGCT GAAGAATGTC AAACTAGAAG AGGAAGATGA GGAGGATGAG 
CCCGAAGCAG CCGCACTGGA CCTTTCTGTG AATCCTGCGT CTGTAGGAGG ACGCCTCGTC 
TTCTCGGGTT CCAAAAAGAA ATCATCTTCC AGCCTGGGCT CCACTTCATC TCAGGATTCA 
GTTTCTTCAG ATTCTGAAAC CGCCGAGTCT GTCTCTTGCC AGGGCCAAGA GAAAACGGGA 
GTTCTCACCG TGCACAGCTA TGCCAGAGGG GACGGCAAGG CTGCCACAGG AGAGCCGAGT 
GTGAAGAAGA AGCGCAGTGC TCCCCGCAGC ATCAGCGAGC AGGAGCTGGC AGAGGTTGCA 
GATGAGTACA TGCTTTCCCT GGAGGAGAAT AAGAAGACCA AGGGTCGCCG CCAGCCCTTG 
AGCAAGCTCC CACGCCACCA CCCACTCGTG CTGCAGGAGT GCGGCAGCGA TGACGGACAA 
CTGAAGGGAA AGCCCAGAGG AGAACGGACT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006503074.1
CDS	194..2086
Translation	MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRTSYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEQHVDEWNIGRLKTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRRFQPERYKLWKAGKDSMVIDHTLPTPEAAEFLKDSGGLTPRAGSEECPEEDVEAADQGEEGDVKRSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEELSSGQYEMTECPATLAPVRPTHSSVRQVEDSLPFPDYSDPTEVKFEELKNVKLEEEDEEDEPEAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSTSSQDSVSSDSETAESVSCQGQEKTGVLTVHSYARGDGKAATGEPSVKKKRSAPRSISEQELAEVADEYMLSLEENKKTKGRRQPLSKLPRHHPLVLQECGSDDGQLKGKPRGERT

Target ORF information:

RefSeq Version	XM_006503011.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysine (K)-specific demethylase 4A (Kdm4a), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006503011.3

ORF Insert Sequence:

ATGGCTTCTG AATCAGAAAC TTTGAACCCC AGTGCTCGGA TCATGACCTT TTACCCCACC 
ATGGAAGAGT TCCGGAACTT CAGCCGCTAC ATTGCCTACA TTGAATCCCA AGGAGCTCAT 
CGGGCTGGGC TAGCCAAGGT CGTTCCTCCC AAAGAGTGGA AGCCTCGAAC ATCCTACGAC 
GATATTGATG ATCTAGTCAT CCCTGCGCCC ATCCAGCAGC TGGTGACTGG CCAGTCTGGC 
CTCTTCACTC AGTACAACAT ACAGAAGAAA GCCATGACCG TTCGTGAGTT CCGCAAGATC 
GCCAATAGCG ACAAGTACTG CACCCCGCGA TACAGTGAAT TTGAAGAACT TGAGCGTAAA 
TACTGGAAAA ACCTCACATT CAATCCTCCC ATCTATGGAG CAGACGTGAA TGGTACTCTC 
TATGAACAGC ACGTTGATGA GTGGAATATC GGCCGGCTGA AGACCATCCT GGACCTGGTG 
GAGAAGGAGA GCGGGATCAC CATTGAGGGG GTGAACACCC CCTACCTTTA CTTCGGCATG 
TGGAAGACGT CCTTCGCCTG GCACACGGAA GACATGGATC TATACAGCAT CAACTATCTG 
CACTTCGGAG AGCCAAAGTC TTGGTACTCT GTTCCACCTG AGCATGGGAA ACGCCTGGAG 
CGTCTTGCCA AAGGCTTTTT CCCAGGAAGT GCTCAAAGCT GTGAGGCTTT TCTCCGCCAC 
AAGATGACCC TGATCTCCCC ATTAATGCTG AAGAAGTATG GCATTCCCTT TGACAAGGTG 
ACCCAAGAAG CTGGCGAGTT TATGATCACT TTTCCGTATG GTTACCATGC TGGCTTCAAC 
CATGGCTTCA ACTGTGCAGA GTCAACCAAT TTTGCTACCC GTCGGTGGAT TGAGTATGGC 
AAGCAGGCTG TGCTGTGCTC CTGCAGAAAA GATATGGTGA AGATCTCCAT GGACGTGTTC 
GTGAGGAGGT TCCAGCCGGA ACGCTACAAA CTTTGGAAAG CTGGGAAGGA CAGCATGGTT 
ATTGACCACA CTCTGCCCAC ACCGGAAGCA GCCGAGTTCC TGAAGGACAG CGGCGGACTA 
ACCCCGAGAG CAGGGAGTGA GGAGTGCCCA GAGGAGGACG TGGAAGCAGC GGATCAGGGA 
GAGGAGGGGG ATGTGAAGAG AAGCCTGGCC AAGCATCGGA TCGGGACAAA GAGACACAGA 
GTCTGTCTGG AAATACCCCA GGAGGTCAGT CAGAGCGAGC TCTTCCCCAA GGAAGAGCTA 
AGTTCTGGAC AGTATGAGAT GACAGAGTGC CCGGCCACCC TCGCCCCAGT GAGGCCCACC 
CACAGCTCCG TGCGGCAAGT TGAGGACAGT CTTCCCTTCC CAGATTACTC TGACCCCACT 
GAAGTCAAAT TTGAAGAGCT GAAGAATGTC AAACTAGAAG AGGAAGATGA GGAGGATGAG 
CCCGAAGCAG CCGCACTGGA CCTTTCTGTG AATCCTGCGT CTGTAGGAGG ACGCCTCGTC 
TTCTCGGGTT CCAAAAAGAA ATCATCTTCC AGCCTGGGCT CCACTTCATC TCAGGATTCA 
GTTTCTTCAG ATTCTGAAAC CGCCGAGTCT GTCTCTTGCC AGGGCCAAGA GAAAACGGGA 
GTTCTCACCG TGCACAGCTA TGCCAGAGGG GACGGCAAGG CTGCCACAGG AGAGCCGAGT 
GTGAAGAAGA AGCGCAGTGC TCCCCGCAGC ATCAGCGAGC AGGAGCTGGC AGAGGTTGCA 
GATGAGTACA TGCTTTCCCT GGAGGAGAAT AAGAAGACCA AGGGTCGCCG CCAGCCCTTG 
AGCAAGCTCC CACGCCACCA CCCACTCGTG CTGCAGGAGT GCGGCAGCGA TGACGGACAA 
CTGAAGGGAA AGCCCAGAGG AGAACGGACT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kdm4a ( NM_172382.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_759014.2 Mus musculus lysine (K)-specific demethylase 4A (Kdm4a), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu13617
Clone ID Related Accession (Same CDS sequence)	NM_172382.2
Accession Version	NM_172382.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3102bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	lysine-specific demethylase 4A isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY308642.1, AK054095.1 and AL626764.6. On Jun 18, 2009 this sequence version replaced NM_172382.1. Transcript Variant: This variant (2) has an alternate 3' terminal exon, compared to variant 1, that results in a protein (isoform 2) with a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC028866.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164142 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTCTG AATCAGAAAC TTTGAACCCC AGTGCTCGGA TCATGACCTT TTACCCCACC 
ATGGAAGAGT TCCGGAACTT CAGCCGCTAC ATTGCCTACA TTGAATCCCA AGGAGCTCAT 
CGGGCTGGGC TAGCCAAGGT CGTTCCTCCC AAAGAGTGGA AGCCTCGAAC ATCCTACGAC 
GATATTGATG ATCTAGTCAT CCCTGCGCCC ATCCAGCAGC TGGTGACTGG CCAGTCTGGC 
CTCTTCACTC AGTACAACAT ACAGAAGAAA GCCATGACCG TTCGTGAGTT CCGCAAGATC 
GCCAATAGCG ACAAGTACTG CACCCCGCGA TACAGTGAAT TTGAAGAACT TGAGCGTAAA 
TACTGGAAAA ACCTCACATT CAATCCTCCC ATCTATGGAG CAGACGTGAA TGGTACTCTC 
TATGAACAGC ACGTTGATGA GTGGAATATC GGCCGGCTGA AGACCATCCT GGACCTGGTG 
GAGAAGGAGA GCGGGATCAC CATTGAGGGG GTGAACACCC CCTACCTTTA CTTCGGCATG 
TGGAAGACGT CCTTCGCCTG GCACACGGAA GACATGGATC TATACAGCAT CAACTATCTG 
CACTTCGGAG AGCCAAAGTC TTGGTACTCT GTTCCACCTG AGCATGGGAA ACGCCTGGAG 
CGTCTTGCCA AAGGCTTTTT CCCAGGAAGT GCTCAAAGCT GTGAGGCTTT TCTCCGCCAC 
AAGATGACCC TGATCTCCCC ATTAATGCTG AAGAAGTATG GCATTCCCTT TGACAAGGTG 
ACCCAAGAAG CTGGCGAGTT TATGATCACT TTTCCGTATG GTTACCATGC TGGCTTCAAC 
CATGGCTTCA ACTGTGCAGA GTCAACCAAT TTTGCTACCC GTCGGTGGAT TGAGTATGGC 
AAGCAGGCTG TGCTGTGCTC CTGCAGAAAA GATATGGTGA AGATCTCCAT GGACGTGTTC 
GTGAGGAGGT TCCAGCCGGA ACGCTACAAA CTTTGGAAAG CTGGGAAGGA CAGCATGGTT 
ATTGACCACA CTCTGCCCAC ACCGGAAGCA GCCGAGTTCC TGAAGGACAG CGGCGGACTA 
ACCCCGAGAG CAGGGAGTGA GGAGTGCCCA GAGGAGGACG TGGAAGCAGC GGATCAGGGA 
GAGGAGGGGG ATGTGAAGAG AAGCCTGGCC AAGCATCGGA TCGGGACAAA GAGACACAGA 
GTCTGTCTGG AAATACCCCA GGAGGTCAGT CAGAGCGAGC TCTTCCCCAA GGAAGAGCTA 
AGTTCTGGAC AGTATGAGAT GACAGAGTGC CCGGCCACCC TCGCCCCAGT GAGGCCCACC 
CACAGCTCCG TGCGGCAAGT TGAGGACAGT CTTCCCTTCC CAGATTACTC TGACCCCACT 
GAAGTCAAAT TTGAAGAGCT GAAGAATGTC AAACTAGAAG AGGAAGATGA GGAGGATGAG 
CCCGAAGCAG CCGCACTGGA CCTTTCTGTG AATCCTGCGT CTGTAGGAGG ACGCCTCGTC 
TTCTCGGGTT CCAAAAAGAA ATCATCTTCC AGCCTGGGCT CCACTTCATC TCAGGATTCA 
GTTTCTTCAG ATTCTGAAAC CGCCGAGTCT GTCTCTTGCC AGGGCCAAGA GAAAACGGGA 
GTTCTCACCG TGCACAGCTA TGCCAGAGGG GACGGCAAGG CTGCCACAGG AGAGCCGAGT 
GTGAAGAAGA AGCGCAGTGC TCCCCGCAGC ATCAGCGAGC AGGAGCTGGC AGAGGTTGCA 
GATGAGTACA TGCTTTCCCT GGAGGAGAAT AAGAAGACCA AGGGTCGCCG CCAGCCCTTG 
AGCAAGCTCC CACGCCACCA CCCACTCGTG CTGCAGGAGT GCGGCAGCGA TGACGAGACT 
TCTGAGCAGC TGACCCCCGA GGAGGAGGCT GAGGAGACAG AGGCTTGGGC CAAGCCTCTG 
AGCCAGCTGT GGCAGAACCG ACCCCCGAAC TTTGAGGCTG AAAAGGAATT CAATGAGATC 
ATGGCCCAAC AGGCCCCTCA CTGTGCTGTG TGTATGATCT TCCAGACCTA CCATCAGGTG 
GAATTTGGAG CCTTCAGTCA GAGCTGTGGG GATGCTTCAG AGCCGGCTGC CCAGACTCAG 
AGGACCAAGC CACTGATCCC CGAAATGTGC TTTACCACCA CTGGCTGCAG CACAGACATC 
AATCTGTCCA CCCCGTACCT AGAGGAGGAT GGCACCAGCA TGCTAGTGTC CTGCAAGAAG 
TGCAGTGTCC GGGTCCACGC CAGTTGCTAT GGCGTCCCTC CTGCCAAGGC TTCTGAAGAA 
TGGATGTGCT CTCGATGTTC AGCCAATGCC CTGGAGGAAG ACTGCTGCTT ATGCTCGTTG 
CGTGGAGGGG CCCTGCAGAG AGCCAATGAC GACAGATGGG TTCATGTTTC ATGTGCAGTG 
GCAATTCTAG AAGCAAGGTT TGTCAACATT GCTGAAAGAA GTCCAGTGGA TGTGAGCAAA 
ATCCCTCTGC CCCGCTTCAA ACTGAAGTGT GTTTTTTGTA AGAAGCGGAG AAAACGGAAT 
GCTGGCTGCT GTGTGCAGTG CTCCCATGGC CGCTGCCCCA CTGCCTTCCA TGTGAGCTGT 
GCCCAGGCTG CTGGGGTGAT GATGCAACCC GACGACTGGC CCTTTGTTGT CTTCATCACG 
TGCTTCCGTC ACAAGATTCC CAATCTGGAG CGTGCTAAGG GAGCCTTGCT GAGCATCACG 
GCGGGCCAGA AGGTTATCAG CAAACACAAG AACGGGCGCT TCTACCAGTG TGAGGTGGTC 
AGACTCACCA CCGAGACCTT CTACGAAGTC AACTTTGACG ACGGCTCCTT CAGTGACAAC 
CTTTATCCTG AGGACATAGT GGTAATGTCT GAAAGCGGCT TCTGGCAGCA CTTTGGGTCT 
GGGACATCTT CTTGTTATTG CCGGCTGGAT GACTGTGGTC TCTTTGCCTG CCCCTGGTCA 
GTTTCCAAAC AGAAAGAGCC TTTATTCCCA GGTTCCCTTT CAAGGAAGAG TGGACATGCT 
GGGGCGCTCA GCTTCCCCGA GGAGTTCAGA GGAGTCAGTG TTCCCTGCAG TCCACTGAAA 
TATGCTTATA TCTCAGACCA AATTATTTCT AATAGCATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_759014.2
CDS	196..3297
Translation	MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRTSYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEQHVDEWNIGRLKTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRRFQPERYKLWKAGKDSMVIDHTLPTPEAAEFLKDSGGLTPRAGSEECPEEDVEAADQGEEGDVKRSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEELSSGQYEMTECPATLAPVRPTHSSVRQVEDSLPFPDYSDPTEVKFEELKNVKLEEEDEEDEPEAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSTSSQDSVSSDSETAESVSCQGQEKTGVLTVHSYARGDGKAATGEPSVKKKRSAPRSISEQELAEVADEYMLSLEENKKTKGRRQPLSKLPRHHPLVLQECGSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNEIMAQQAPHCAVCMIFQTYHQVEFGAFSQSCGDASEPAAQTQRTKPLIPEMCFTTTGCSTDINLSTPYLEEDGTSMLVSCKKCSVRVHASCYGVPPAKASEEWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCVFCKKRRKRNAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALLSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVVMSESGFWQHFGSGTSSCYCRLDDCGLFACPWSVSKQKEPLFPGSLSRKSGHAGALSFPEEFRGVSVPCSPLKYAYISDQIISNSI

Target ORF information:

RefSeq Version	NM_172382.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysine (K)-specific demethylase 4A (Kdm4a), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172382.2

ORF Insert Sequence:

ATGGCTTCTG AATCAGAAAC TTTGAACCCC AGTGCTCGGA TCATGACCTT TTACCCCACC 
ATGGAAGAGT TCCGGAACTT CAGCCGCTAC ATTGCCTACA TTGAATCCCA AGGAGCTCAT 
CGGGCTGGGC TAGCCAAGGT CGTTCCTCCC AAAGAGTGGA AGCCTCGAAC ATCCTACGAC 
GATATTGATG ATCTAGTCAT CCCTGCGCCC ATCCAGCAGC TGGTGACTGG CCAGTCTGGC 
CTCTTCACTC AGTACAACAT ACAGAAGAAA GCCATGACCG TTCGTGAGTT CCGCAAGATC 
GCCAATAGCG ACAAGTACTG CACCCCGCGA TACAGTGAAT TTGAAGAACT TGAGCGTAAA 
TACTGGAAAA ACCTCACATT CAATCCTCCC ATCTATGGAG CAGACGTGAA TGGTACTCTC 
TATGAACAGC ACGTTGATGA GTGGAATATC GGCCGGCTGA AGACCATCCT GGACCTGGTG 
GAGAAGGAGA GCGGGATCAC CATTGAGGGG GTGAACACCC CCTACCTTTA CTTCGGCATG 
TGGAAGACGT CCTTCGCCTG GCACACGGAA GACATGGATC TATACAGCAT CAACTATCTG 
CACTTCGGAG AGCCAAAGTC TTGGTACTCT GTTCCACCTG AGCATGGGAA ACGCCTGGAG 
CGTCTTGCCA AAGGCTTTTT CCCAGGAAGT GCTCAAAGCT GTGAGGCTTT TCTCCGCCAC 
AAGATGACCC TGATCTCCCC ATTAATGCTG AAGAAGTATG GCATTCCCTT TGACAAGGTG 
ACCCAAGAAG CTGGCGAGTT TATGATCACT TTTCCGTATG GTTACCATGC TGGCTTCAAC 
CATGGCTTCA ACTGTGCAGA GTCAACCAAT TTTGCTACCC GTCGGTGGAT TGAGTATGGC 
AAGCAGGCTG TGCTGTGCTC CTGCAGAAAA GATATGGTGA AGATCTCCAT GGACGTGTTC 
GTGAGGAGGT TCCAGCCGGA ACGCTACAAA CTTTGGAAAG CTGGGAAGGA CAGCATGGTT 
ATTGACCACA CTCTGCCCAC ACCGGAAGCA GCCGAGTTCC TGAAGGACAG CGGCGGACTA 
ACCCCGAGAG CAGGGAGTGA GGAGTGCCCA GAGGAGGACG TGGAAGCAGC GGATCAGGGA 
GAGGAGGGGG ATGTGAAGAG AAGCCTGGCC AAGCATCGGA TCGGGACAAA GAGACACAGA 
GTCTGTCTGG AAATACCCCA GGAGGTCAGT CAGAGCGAGC TCTTCCCCAA GGAAGAGCTA 
AGTTCTGGAC AGTATGAGAT GACAGAGTGC CCGGCCACCC TCGCCCCAGT GAGGCCCACC 
CACAGCTCCG TGCGGCAAGT TGAGGACAGT CTTCCCTTCC CAGATTACTC TGACCCCACT 
GAAGTCAAAT TTGAAGAGCT GAAGAATGTC AAACTAGAAG AGGAAGATGA GGAGGATGAG 
CCCGAAGCAG CCGCACTGGA CCTTTCTGTG AATCCTGCGT CTGTAGGAGG ACGCCTCGTC 
TTCTCGGGTT CCAAAAAGAA ATCATCTTCC AGCCTGGGCT CCACTTCATC TCAGGATTCA 
GTTTCTTCAG ATTCTGAAAC CGCCGAGTCT GTCTCTTGCC AGGGCCAAGA GAAAACGGGA 
GTTCTCACCG TGCACAGCTA TGCCAGAGGG GACGGCAAGG CTGCCACAGG AGAGCCGAGT 
GTGAAGAAGA AGCGCAGTGC TCCCCGCAGC ATCAGCGAGC AGGAGCTGGC AGAGGTTGCA 
GATGAGTACA TGCTTTCCCT GGAGGAGAAT AAGAAGACCA AGGGTCGCCG CCAGCCCTTG 
AGCAAGCTCC CACGCCACCA CCCACTCGTG CTGCAGGAGT GCGGCAGCGA TGACGAGACT 
TCTGAGCAGC TGACCCCCGA GGAGGAGGCT GAGGAGACAG AGGCTTGGGC CAAGCCTCTG 
AGCCAGCTGT GGCAGAACCG ACCCCCGAAC TTTGAGGCTG AAAAGGAATT CAATGAGATC 
ATGGCCCAAC AGGCCCCTCA CTGTGCTGTG TGTATGATCT TCCAGACCTA CCATCAGGTG 
GAATTTGGAG CCTTCAGTCA GAGCTGTGGG GATGCTTCAG AGCCGGCTGC CCAGACTCAG 
AGGACCAAGC CACTGATCCC CGAAATGTGC TTTACCACCA CTGGCTGCAG CACAGACATC 
AATCTGTCCA CCCCGTACCT AGAGGAGGAT GGCACCAGCA TGCTAGTGTC CTGCAAGAAG 
TGCAGTGTCC GGGTCCACGC CAGTTGCTAT GGCGTCCCTC CTGCCAAGGC TTCTGAAGAA 
TGGATGTGCT CTCGATGTTC AGCCAATGCC CTGGAGGAAG ACTGCTGCTT ATGCTCGTTG 
CGTGGAGGGG CCCTGCAGAG AGCCAATGAC GACAGATGGG TTCATGTTTC ATGTGCAGTG 
GCAATTCTAG AAGCAAGGTT TGTCAACATT GCTGAAAGAA GTCCAGTGGA TGTGAGCAAA 
ATCCCTCTGC CCCGCTTCAA ACTGAAGTGT GTTTTTTGTA AGAAGCGGAG AAAACGGAAT 
GCTGGCTGCT GTGTGCAGTG CTCCCATGGC CGCTGCCCCA CTGCCTTCCA TGTGAGCTGT 
GCCCAGGCTG CTGGGGTGAT GATGCAACCC GACGACTGGC CCTTTGTTGT CTTCATCACG 
TGCTTCCGTC ACAAGATTCC CAATCTGGAG CGTGCTAAGG GAGCCTTGCT GAGCATCACG 
GCGGGCCAGA AGGTTATCAG CAAACACAAG AACGGGCGCT TCTACCAGTG TGAGGTGGTC 
AGACTCACCA CCGAGACCTT CTACGAAGTC AACTTTGACG ACGGCTCCTT CAGTGACAAC 
CTTTATCCTG AGGACATAGT GGTAATGTCT GAAAGCGGCT TCTGGCAGCA CTTTGGGTCT 
GGGACATCTT CTTGTTATTG CCGGCTGGAT GACTGTGGTC TCTTTGCCTG CCCCTGGTCA 
GTTTCCAAAC AGAAAGAGCC TTTATTCCCA GGTTCCCTTT CAAGGAAGAG TGGACATGCT 
GGGGCGCTCA GCTTCCCCGA GGAGTTCAGA GGAGTCAGTG TTCCCTGCAG TCCACTGAAA 
TATGCTTATA TCTCAGACCA AATTATTTCT AATAGCATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kdm4a ( NM_001161823.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001155295.1 Mus musculus lysine (K)-specific demethylase 4A (Kdm4a), transcript variant 1, mRNA.

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CloneID	OMu14006
Clone ID Related Accession (Same CDS sequence)	XM_006503010.2 , NM_001161823.1
Accession Version	NM_001161823.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3195bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	lysine-specific demethylase 4A isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY308642.1, AK054095.1 and AL626764.6. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK145066.1, AK054095.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164142 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTCTG AATCAGAAAC TTTGAACCCC AGTGCTCGGA TCATGACCTT TTACCCCACC 
ATGGAAGAGT TCCGGAACTT CAGCCGCTAC ATTGCCTACA TTGAATCCCA AGGAGCTCAT 
CGGGCTGGGC TAGCCAAGGT CGTTCCTCCC AAAGAGTGGA AGCCTCGAAC ATCCTACGAC 
GATATTGATG ATCTAGTCAT CCCTGCGCCC ATCCAGCAGC TGGTGACTGG CCAGTCTGGC 
CTCTTCACTC AGTACAACAT ACAGAAGAAA GCCATGACCG TTCGTGAGTT CCGCAAGATC 
GCCAATAGCG ACAAGTACTG CACCCCGCGA TACAGTGAAT TTGAAGAACT TGAGCGTAAA 
TACTGGAAAA ACCTCACATT CAATCCTCCC ATCTATGGAG CAGACGTGAA TGGTACTCTC 
TATGAACAGC ACGTTGATGA GTGGAATATC GGCCGGCTGA AGACCATCCT GGACCTGGTG 
GAGAAGGAGA GCGGGATCAC CATTGAGGGG GTGAACACCC CCTACCTTTA CTTCGGCATG 
TGGAAGACGT CCTTCGCCTG GCACACGGAA GACATGGATC TATACAGCAT CAACTATCTG 
CACTTCGGAG AGCCAAAGTC TTGGTACTCT GTTCCACCTG AGCATGGGAA ACGCCTGGAG 
CGTCTTGCCA AAGGCTTTTT CCCAGGAAGT GCTCAAAGCT GTGAGGCTTT TCTCCGCCAC 
AAGATGACCC TGATCTCCCC ATTAATGCTG AAGAAGTATG GCATTCCCTT TGACAAGGTG 
ACCCAAGAAG CTGGCGAGTT TATGATCACT TTTCCGTATG GTTACCATGC TGGCTTCAAC 
CATGGCTTCA ACTGTGCAGA GTCAACCAAT TTTGCTACCC GTCGGTGGAT TGAGTATGGC 
AAGCAGGCTG TGCTGTGCTC CTGCAGAAAA GATATGGTGA AGATCTCCAT GGACGTGTTC 
GTGAGGAGGT TCCAGCCGGA ACGCTACAAA CTTTGGAAAG CTGGGAAGGA CAGCATGGTT 
ATTGACCACA CTCTGCCCAC ACCGGAAGCA GCCGAGTTCC TGAAGGACAG CGGCGGACTA 
ACCCCGAGAG CAGGGAGTGA GGAGTGCCCA GAGGAGGACG TGGAAGCAGC GGATCAGGGA 
GAGGAGGGGG ATGTGAAGAG AAGCCTGGCC AAGCATCGGA TCGGGACAAA GAGACACAGA 
GTCTGTCTGG AAATACCCCA GGAGGTCAGT CAGAGCGAGC TCTTCCCCAA GGAAGAGCTA 
AGTTCTGGAC AGTATGAGAT GACAGAGTGC CCGGCCACCC TCGCCCCAGT GAGGCCCACC 
CACAGCTCCG TGCGGCAAGT TGAGGACAGT CTTCCCTTCC CAGATTACTC TGACCCCACT 
GAAGTCAAAT TTGAAGAGCT GAAGAATGTC AAACTAGAAG AGGAAGATGA GGAGGATGAG 
CCCGAAGCAG CCGCACTGGA CCTTTCTGTG AATCCTGCGT CTGTAGGAGG ACGCCTCGTC 
TTCTCGGGTT CCAAAAAGAA ATCATCTTCC AGCCTGGGCT CCACTTCATC TCAGGATTCA 
GTTTCTTCAG ATTCTGAAAC CGCCGAGTCT GTCTCTTGCC AGGGCCAAGA GAAAACGGGA 
GTTCTCACCG TGCACAGCTA TGCCAGAGGG GACGGCAAGG CTGCCACAGG AGAGCCGAGT 
GTGAAGAAGA AGCGCAGTGC TCCCCGCAGC ATCAGCGAGC AGGAGCTGGC AGAGGTTGCA 
GATGAGTACA TGCTTTCCCT GGAGGAGAAT AAGAAGACCA AGGGTCGCCG CCAGCCCTTG 
AGCAAGCTCC CACGCCACCA CCCACTCGTG CTGCAGGAGT GCGGCAGCGA TGACGAGACT 
TCTGAGCAGC TGACCCCCGA GGAGGAGGCT GAGGAGACAG AGGCTTGGGC CAAGCCTCTG 
AGCCAGCTGT GGCAGAACCG ACCCCCGAAC TTTGAGGCTG AAAAGGAATT CAATGAGATC 
ATGGCCCAAC AGGCCCCTCA CTGTGCTGTG TGTATGATCT TCCAGACCTA CCATCAGGTG 
GAATTTGGAG CCTTCAGTCA GAGCTGTGGG GATGCTTCAG AGCCGGCTGC CCAGACTCAG 
AGGACCAAGC CACTGATCCC CGAAATGTGC TTTACCACCA CTGGCTGCAG CACAGACATC 
AATCTGTCCA CCCCGTACCT AGAGGAGGAT GGCACCAGCA TGCTAGTGTC CTGCAAGAAG 
TGCAGTGTCC GGGTCCACGC CAGTTGCTAT GGCGTCCCTC CTGCCAAGGC TTCTGAAGAA 
TGGATGTGCT CTCGATGTTC AGCCAATGCC CTGGAGGAAG ACTGCTGCTT ATGCTCGTTG 
CGTGGAGGGG CCCTGCAGAG AGCCAATGAC GACAGATGGG TTCATGTTTC ATGTGCAGTG 
GCAATTCTAG AAGCAAGGTT TGTCAACATT GCTGAAAGAA GTCCAGTGGA TGTGAGCAAA 
ATCCCTCTGC CCCGCTTCAA ACTGAAGTGT GTTTTTTGTA AGAAGCGGAG AAAACGGAAT 
GCTGGCTGCT GTGTGCAGTG CTCCCATGGC CGCTGCCCCA CTGCCTTCCA TGTGAGCTGT 
GCCCAGGCTG CTGGGGTGAT GATGCAACCC GACGACTGGC CCTTTGTTGT CTTCATCACG 
TGCTTCCGTC ACAAGATTCC CAATCTGGAG CGTGCTAAGG GAGCCTTGCT GAGCATCACG 
GCGGGCCAGA AGGTTATCAG CAAACACAAG AACGGGCGCT TCTACCAGTG TGAGGTGGTC 
AGACTCACCA CCGAGACCTT CTACGAAGTC AACTTTGACG ACGGCTCCTT CAGTGACAAC 
CTTTATCCTG AGGACATAGT GAGTCAGGAC TGTCTCCAAC TGGGGCCTCC TGCTGAAGGT 
GAAGTGGTTC AAGTCAGATG GACAGATGGC CAAGTCTATG GGGCTAAGTT TGTGGCCTCC 
CACCCCATCC AGATGTACCA GGTGGAGTTT GAGGATGGCT CGCAGCTGGT GGTTAAGAGA 
GATGATGTAT ACACACTCGA TGAAGAGCTT CCCAAGAGAG TCAAGTCTAG ACTGTCGGTG 
GCTTCAGACA TGCGCTTCAA TGAGATTTTC ACAGAGAAGG AAGTGAAGCA AGAAAAGAAG 
AGGCAACGGG TCATCAACTC GCGGTACCGG GAGGATTACA TCGAGCCAGC GCTGTACCGG 
GCCATCATGG AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001155295.1
CDS	196..3390
Translation	MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRTSYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEQHVDEWNIGRLKTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRRFQPERYKLWKAGKDSMVIDHTLPTPEAAEFLKDSGGLTPRAGSEECPEEDVEAADQGEEGDVKRSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEELSSGQYEMTECPATLAPVRPTHSSVRQVEDSLPFPDYSDPTEVKFEELKNVKLEEEDEEDEPEAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSTSSQDSVSSDSETAESVSCQGQEKTGVLTVHSYARGDGKAATGEPSVKKKRSAPRSISEQELAEVADEYMLSLEENKKTKGRRQPLSKLPRHHPLVLQECGSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNEIMAQQAPHCAVCMIFQTYHQVEFGAFSQSCGDASEPAAQTQRTKPLIPEMCFTTTGCSTDINLSTPYLEEDGTSMLVSCKKCSVRVHASCYGVPPAKASEEWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCVFCKKRRKRNAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALLSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQLGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQEKKRQRVINSRYREDYIEPALYRAIME

Target ORF information:

RefSeq Version	NM_001161823.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysine (K)-specific demethylase 4A (Kdm4a), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001161823.1

ORF Insert Sequence:

ATGGCTTCTG AATCAGAAAC TTTGAACCCC AGTGCTCGGA TCATGACCTT TTACCCCACC 
ATGGAAGAGT TCCGGAACTT CAGCCGCTAC ATTGCCTACA TTGAATCCCA AGGAGCTCAT 
CGGGCTGGGC TAGCCAAGGT CGTTCCTCCC AAAGAGTGGA AGCCTCGAAC ATCCTACGAC 
GATATTGATG ATCTAGTCAT CCCTGCGCCC ATCCAGCAGC TGGTGACTGG CCAGTCTGGC 
CTCTTCACTC AGTACAACAT ACAGAAGAAA GCCATGACCG TTCGTGAGTT CCGCAAGATC 
GCCAATAGCG ACAAGTACTG CACCCCGCGA TACAGTGAAT TTGAAGAACT TGAGCGTAAA 
TACTGGAAAA ACCTCACATT CAATCCTCCC ATCTATGGAG CAGACGTGAA TGGTACTCTC 
TATGAACAGC ACGTTGATGA GTGGAATATC GGCCGGCTGA AGACCATCCT GGACCTGGTG 
GAGAAGGAGA GCGGGATCAC CATTGAGGGG GTGAACACCC CCTACCTTTA CTTCGGCATG 
TGGAAGACGT CCTTCGCCTG GCACACGGAA GACATGGATC TATACAGCAT CAACTATCTG 
CACTTCGGAG AGCCAAAGTC TTGGTACTCT GTTCCACCTG AGCATGGGAA ACGCCTGGAG 
CGTCTTGCCA AAGGCTTTTT CCCAGGAAGT GCTCAAAGCT GTGAGGCTTT TCTCCGCCAC 
AAGATGACCC TGATCTCCCC ATTAATGCTG AAGAAGTATG GCATTCCCTT TGACAAGGTG 
ACCCAAGAAG CTGGCGAGTT TATGATCACT TTTCCGTATG GTTACCATGC TGGCTTCAAC 
CATGGCTTCA ACTGTGCAGA GTCAACCAAT TTTGCTACCC GTCGGTGGAT TGAGTATGGC 
AAGCAGGCTG TGCTGTGCTC CTGCAGAAAA GATATGGTGA AGATCTCCAT GGACGTGTTC 
GTGAGGAGGT TCCAGCCGGA ACGCTACAAA CTTTGGAAAG CTGGGAAGGA CAGCATGGTT 
ATTGACCACA CTCTGCCCAC ACCGGAAGCA GCCGAGTTCC TGAAGGACAG CGGCGGACTA 
ACCCCGAGAG CAGGGAGTGA GGAGTGCCCA GAGGAGGACG TGGAAGCAGC GGATCAGGGA 
GAGGAGGGGG ATGTGAAGAG AAGCCTGGCC AAGCATCGGA TCGGGACAAA GAGACACAGA 
GTCTGTCTGG AAATACCCCA GGAGGTCAGT CAGAGCGAGC TCTTCCCCAA GGAAGAGCTA 
AGTTCTGGAC AGTATGAGAT GACAGAGTGC CCGGCCACCC TCGCCCCAGT GAGGCCCACC 
CACAGCTCCG TGCGGCAAGT TGAGGACAGT CTTCCCTTCC CAGATTACTC TGACCCCACT 
GAAGTCAAAT TTGAAGAGCT GAAGAATGTC AAACTAGAAG AGGAAGATGA GGAGGATGAG 
CCCGAAGCAG CCGCACTGGA CCTTTCTGTG AATCCTGCGT CTGTAGGAGG ACGCCTCGTC 
TTCTCGGGTT CCAAAAAGAA ATCATCTTCC AGCCTGGGCT CCACTTCATC TCAGGATTCA 
GTTTCTTCAG ATTCTGAAAC CGCCGAGTCT GTCTCTTGCC AGGGCCAAGA GAAAACGGGA 
GTTCTCACCG TGCACAGCTA TGCCAGAGGG GACGGCAAGG CTGCCACAGG AGAGCCGAGT 
GTGAAGAAGA AGCGCAGTGC TCCCCGCAGC ATCAGCGAGC AGGAGCTGGC AGAGGTTGCA 
GATGAGTACA TGCTTTCCCT GGAGGAGAAT AAGAAGACCA AGGGTCGCCG CCAGCCCTTG 
AGCAAGCTCC CACGCCACCA CCCACTCGTG CTGCAGGAGT GCGGCAGCGA TGACGAGACT 
TCTGAGCAGC TGACCCCCGA GGAGGAGGCT GAGGAGACAG AGGCTTGGGC CAAGCCTCTG 
AGCCAGCTGT GGCAGAACCG ACCCCCGAAC TTTGAGGCTG AAAAGGAATT CAATGAGATC 
ATGGCCCAAC AGGCCCCTCA CTGTGCTGTG TGTATGATCT TCCAGACCTA CCATCAGGTG 
GAATTTGGAG CCTTCAGTCA GAGCTGTGGG GATGCTTCAG AGCCGGCTGC CCAGACTCAG 
AGGACCAAGC CACTGATCCC CGAAATGTGC TTTACCACCA CTGGCTGCAG CACAGACATC 
AATCTGTCCA CCCCGTACCT AGAGGAGGAT GGCACCAGCA TGCTAGTGTC CTGCAAGAAG 
TGCAGTGTCC GGGTCCACGC CAGTTGCTAT GGCGTCCCTC CTGCCAAGGC TTCTGAAGAA 
TGGATGTGCT CTCGATGTTC AGCCAATGCC CTGGAGGAAG ACTGCTGCTT ATGCTCGTTG 
CGTGGAGGGG CCCTGCAGAG AGCCAATGAC GACAGATGGG TTCATGTTTC ATGTGCAGTG 
GCAATTCTAG AAGCAAGGTT TGTCAACATT GCTGAAAGAA GTCCAGTGGA TGTGAGCAAA 
ATCCCTCTGC CCCGCTTCAA ACTGAAGTGT GTTTTTTGTA AGAAGCGGAG AAAACGGAAT 
GCTGGCTGCT GTGTGCAGTG CTCCCATGGC CGCTGCCCCA CTGCCTTCCA TGTGAGCTGT 
GCCCAGGCTG CTGGGGTGAT GATGCAACCC GACGACTGGC CCTTTGTTGT CTTCATCACG 
TGCTTCCGTC ACAAGATTCC CAATCTGGAG CGTGCTAAGG GAGCCTTGCT GAGCATCACG 
GCGGGCCAGA AGGTTATCAG CAAACACAAG AACGGGCGCT TCTACCAGTG TGAGGTGGTC 
AGACTCACCA CCGAGACCTT CTACGAAGTC AACTTTGACG ACGGCTCCTT CAGTGACAAC 
CTTTATCCTG AGGACATAGT GAGTCAGGAC TGTCTCCAAC TGGGGCCTCC TGCTGAAGGT 
GAAGTGGTTC AAGTCAGATG GACAGATGGC CAAGTCTATG GGGCTAAGTT TGTGGCCTCC 
CACCCCATCC AGATGTACCA GGTGGAGTTT GAGGATGGCT CGCAGCTGGT GGTTAAGAGA 
GATGATGTAT ACACACTCGA TGAAGAGCTT CCCAAGAGAG TCAAGTCTAG ACTGTCGGTG 
GCTTCAGACA TGCGCTTCAA TGAGATTTTC ACAGAGAAGG AAGTGAAGCA AGAAAAGAAG 
AGGCAACGGG TCATCAACTC GCGGTACCGG GAGGATTACA TCGAGCCAGC GCTGTACCGG 
GCCATCATGG AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kdm4a ( XM_006503010.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006503073.1 Mus musculus lysine (K)-specific demethylase 4A (Kdm4a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu14006
Clone ID Related Accession (Same CDS sequence)	XM_006503010.2 , NM_001161823.1
Accession Version	XM_006503010.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3195bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	lysine-specific demethylase 4A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006503010.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCTG AATCAGAAAC TTTGAACCCC AGTGCTCGGA TCATGACCTT TTACCCCACC 
ATGGAAGAGT TCCGGAACTT CAGCCGCTAC ATTGCCTACA TTGAATCCCA AGGAGCTCAT 
CGGGCTGGGC TAGCCAAGGT CGTTCCTCCC AAAGAGTGGA AGCCTCGAAC ATCCTACGAC 
GATATTGATG ATCTAGTCAT CCCTGCGCCC ATCCAGCAGC TGGTGACTGG CCAGTCTGGC 
CTCTTCACTC AGTACAACAT ACAGAAGAAA GCCATGACCG TTCGTGAGTT CCGCAAGATC 
GCCAATAGCG ACAAGTACTG CACCCCGCGA TACAGTGAAT TTGAAGAACT TGAGCGTAAA 
TACTGGAAAA ACCTCACATT CAATCCTCCC ATCTATGGAG CAGACGTGAA TGGTACTCTC 
TATGAACAGC ACGTTGATGA GTGGAATATC GGCCGGCTGA AGACCATCCT GGACCTGGTG 
GAGAAGGAGA GCGGGATCAC CATTGAGGGG GTGAACACCC CCTACCTTTA CTTCGGCATG 
TGGAAGACGT CCTTCGCCTG GCACACGGAA GACATGGATC TATACAGCAT CAACTATCTG 
CACTTCGGAG AGCCAAAGTC TTGGTACTCT GTTCCACCTG AGCATGGGAA ACGCCTGGAG 
CGTCTTGCCA AAGGCTTTTT CCCAGGAAGT GCTCAAAGCT GTGAGGCTTT TCTCCGCCAC 
AAGATGACCC TGATCTCCCC ATTAATGCTG AAGAAGTATG GCATTCCCTT TGACAAGGTG 
ACCCAAGAAG CTGGCGAGTT TATGATCACT TTTCCGTATG GTTACCATGC TGGCTTCAAC 
CATGGCTTCA ACTGTGCAGA GTCAACCAAT TTTGCTACCC GTCGGTGGAT TGAGTATGGC 
AAGCAGGCTG TGCTGTGCTC CTGCAGAAAA GATATGGTGA AGATCTCCAT GGACGTGTTC 
GTGAGGAGGT TCCAGCCGGA ACGCTACAAA CTTTGGAAAG CTGGGAAGGA CAGCATGGTT 
ATTGACCACA CTCTGCCCAC ACCGGAAGCA GCCGAGTTCC TGAAGGACAG CGGCGGACTA 
ACCCCGAGAG CAGGGAGTGA GGAGTGCCCA GAGGAGGACG TGGAAGCAGC GGATCAGGGA 
GAGGAGGGGG ATGTGAAGAG AAGCCTGGCC AAGCATCGGA TCGGGACAAA GAGACACAGA 
GTCTGTCTGG AAATACCCCA GGAGGTCAGT CAGAGCGAGC TCTTCCCCAA GGAAGAGCTA 
AGTTCTGGAC AGTATGAGAT GACAGAGTGC CCGGCCACCC TCGCCCCAGT GAGGCCCACC 
CACAGCTCCG TGCGGCAAGT TGAGGACAGT CTTCCCTTCC CAGATTACTC TGACCCCACT 
GAAGTCAAAT TTGAAGAGCT GAAGAATGTC AAACTAGAAG AGGAAGATGA GGAGGATGAG 
CCCGAAGCAG CCGCACTGGA CCTTTCTGTG AATCCTGCGT CTGTAGGAGG ACGCCTCGTC 
TTCTCGGGTT CCAAAAAGAA ATCATCTTCC AGCCTGGGCT CCACTTCATC TCAGGATTCA 
GTTTCTTCAG ATTCTGAAAC CGCCGAGTCT GTCTCTTGCC AGGGCCAAGA GAAAACGGGA 
GTTCTCACCG TGCACAGCTA TGCCAGAGGG GACGGCAAGG CTGCCACAGG AGAGCCGAGT 
GTGAAGAAGA AGCGCAGTGC TCCCCGCAGC ATCAGCGAGC AGGAGCTGGC AGAGGTTGCA 
GATGAGTACA TGCTTTCCCT GGAGGAGAAT AAGAAGACCA AGGGTCGCCG CCAGCCCTTG 
AGCAAGCTCC CACGCCACCA CCCACTCGTG CTGCAGGAGT GCGGCAGCGA TGACGAGACT 
TCTGAGCAGC TGACCCCCGA GGAGGAGGCT GAGGAGACAG AGGCTTGGGC CAAGCCTCTG 
AGCCAGCTGT GGCAGAACCG ACCCCCGAAC TTTGAGGCTG AAAAGGAATT CAATGAGATC 
ATGGCCCAAC AGGCCCCTCA CTGTGCTGTG TGTATGATCT TCCAGACCTA CCATCAGGTG 
GAATTTGGAG CCTTCAGTCA GAGCTGTGGG GATGCTTCAG AGCCGGCTGC CCAGACTCAG 
AGGACCAAGC CACTGATCCC CGAAATGTGC TTTACCACCA CTGGCTGCAG CACAGACATC 
AATCTGTCCA CCCCGTACCT AGAGGAGGAT GGCACCAGCA TGCTAGTGTC CTGCAAGAAG 
TGCAGTGTCC GGGTCCACGC CAGTTGCTAT GGCGTCCCTC CTGCCAAGGC TTCTGAAGAA 
TGGATGTGCT CTCGATGTTC AGCCAATGCC CTGGAGGAAG ACTGCTGCTT ATGCTCGTTG 
CGTGGAGGGG CCCTGCAGAG AGCCAATGAC GACAGATGGG TTCATGTTTC ATGTGCAGTG 
GCAATTCTAG AAGCAAGGTT TGTCAACATT GCTGAAAGAA GTCCAGTGGA TGTGAGCAAA 
ATCCCTCTGC CCCGCTTCAA ACTGAAGTGT GTTTTTTGTA AGAAGCGGAG AAAACGGAAT 
GCTGGCTGCT GTGTGCAGTG CTCCCATGGC CGCTGCCCCA CTGCCTTCCA TGTGAGCTGT 
GCCCAGGCTG CTGGGGTGAT GATGCAACCC GACGACTGGC CCTTTGTTGT CTTCATCACG 
TGCTTCCGTC ACAAGATTCC CAATCTGGAG CGTGCTAAGG GAGCCTTGCT GAGCATCACG 
GCGGGCCAGA AGGTTATCAG CAAACACAAG AACGGGCGCT TCTACCAGTG TGAGGTGGTC 
AGACTCACCA CCGAGACCTT CTACGAAGTC AACTTTGACG ACGGCTCCTT CAGTGACAAC 
CTTTATCCTG AGGACATAGT GAGTCAGGAC TGTCTCCAAC TGGGGCCTCC TGCTGAAGGT 
GAAGTGGTTC AAGTCAGATG GACAGATGGC CAAGTCTATG GGGCTAAGTT TGTGGCCTCC 
CACCCCATCC AGATGTACCA GGTGGAGTTT GAGGATGGCT CGCAGCTGGT GGTTAAGAGA 
GATGATGTAT ACACACTCGA TGAAGAGCTT CCCAAGAGAG TCAAGTCTAG ACTGTCGGTG 
GCTTCAGACA TGCGCTTCAA TGAGATTTTC ACAGAGAAGG AAGTGAAGCA AGAAAAGAAG 
AGGCAACGGG TCATCAACTC GCGGTACCGG GAGGATTACA TCGAGCCAGC GCTGTACCGG 
GCCATCATGG AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006503073.1
CDS	148..3342
Translation	MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRTSYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEQHVDEWNIGRLKTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRRFQPERYKLWKAGKDSMVIDHTLPTPEAAEFLKDSGGLTPRAGSEECPEEDVEAADQGEEGDVKRSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEELSSGQYEMTECPATLAPVRPTHSSVRQVEDSLPFPDYSDPTEVKFEELKNVKLEEEDEEDEPEAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSTSSQDSVSSDSETAESVSCQGQEKTGVLTVHSYARGDGKAATGEPSVKKKRSAPRSISEQELAEVADEYMLSLEENKKTKGRRQPLSKLPRHHPLVLQECGSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNEIMAQQAPHCAVCMIFQTYHQVEFGAFSQSCGDASEPAAQTQRTKPLIPEMCFTTTGCSTDINLSTPYLEEDGTSMLVSCKKCSVRVHASCYGVPPAKASEEWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCVFCKKRRKRNAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALLSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQLGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQEKKRQRVINSRYREDYIEPALYRAIME

Target ORF information:

RefSeq Version	XM_006503010.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysine (K)-specific demethylase 4A (Kdm4a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006503010.2

ORF Insert Sequence:

ATGGCTTCTG AATCAGAAAC TTTGAACCCC AGTGCTCGGA TCATGACCTT TTACCCCACC 
ATGGAAGAGT TCCGGAACTT CAGCCGCTAC ATTGCCTACA TTGAATCCCA AGGAGCTCAT 
CGGGCTGGGC TAGCCAAGGT CGTTCCTCCC AAAGAGTGGA AGCCTCGAAC ATCCTACGAC 
GATATTGATG ATCTAGTCAT CCCTGCGCCC ATCCAGCAGC TGGTGACTGG CCAGTCTGGC 
CTCTTCACTC AGTACAACAT ACAGAAGAAA GCCATGACCG TTCGTGAGTT CCGCAAGATC 
GCCAATAGCG ACAAGTACTG CACCCCGCGA TACAGTGAAT TTGAAGAACT TGAGCGTAAA 
TACTGGAAAA ACCTCACATT CAATCCTCCC ATCTATGGAG CAGACGTGAA TGGTACTCTC 
TATGAACAGC ACGTTGATGA GTGGAATATC GGCCGGCTGA AGACCATCCT GGACCTGGTG 
GAGAAGGAGA GCGGGATCAC CATTGAGGGG GTGAACACCC CCTACCTTTA CTTCGGCATG 
TGGAAGACGT CCTTCGCCTG GCACACGGAA GACATGGATC TATACAGCAT CAACTATCTG 
CACTTCGGAG AGCCAAAGTC TTGGTACTCT GTTCCACCTG AGCATGGGAA ACGCCTGGAG 
CGTCTTGCCA AAGGCTTTTT CCCAGGAAGT GCTCAAAGCT GTGAGGCTTT TCTCCGCCAC 
AAGATGACCC TGATCTCCCC ATTAATGCTG AAGAAGTATG GCATTCCCTT TGACAAGGTG 
ACCCAAGAAG CTGGCGAGTT TATGATCACT TTTCCGTATG GTTACCATGC TGGCTTCAAC 
CATGGCTTCA ACTGTGCAGA GTCAACCAAT TTTGCTACCC GTCGGTGGAT TGAGTATGGC 
AAGCAGGCTG TGCTGTGCTC CTGCAGAAAA GATATGGTGA AGATCTCCAT GGACGTGTTC 
GTGAGGAGGT TCCAGCCGGA ACGCTACAAA CTTTGGAAAG CTGGGAAGGA CAGCATGGTT 
ATTGACCACA CTCTGCCCAC ACCGGAAGCA GCCGAGTTCC TGAAGGACAG CGGCGGACTA 
ACCCCGAGAG CAGGGAGTGA GGAGTGCCCA GAGGAGGACG TGGAAGCAGC GGATCAGGGA 
GAGGAGGGGG ATGTGAAGAG AAGCCTGGCC AAGCATCGGA TCGGGACAAA GAGACACAGA 
GTCTGTCTGG AAATACCCCA GGAGGTCAGT CAGAGCGAGC TCTTCCCCAA GGAAGAGCTA 
AGTTCTGGAC AGTATGAGAT GACAGAGTGC CCGGCCACCC TCGCCCCAGT GAGGCCCACC 
CACAGCTCCG TGCGGCAAGT TGAGGACAGT CTTCCCTTCC CAGATTACTC TGACCCCACT 
GAAGTCAAAT TTGAAGAGCT GAAGAATGTC AAACTAGAAG AGGAAGATGA GGAGGATGAG 
CCCGAAGCAG CCGCACTGGA CCTTTCTGTG AATCCTGCGT CTGTAGGAGG ACGCCTCGTC 
TTCTCGGGTT CCAAAAAGAA ATCATCTTCC AGCCTGGGCT CCACTTCATC TCAGGATTCA 
GTTTCTTCAG ATTCTGAAAC CGCCGAGTCT GTCTCTTGCC AGGGCCAAGA GAAAACGGGA 
GTTCTCACCG TGCACAGCTA TGCCAGAGGG GACGGCAAGG CTGCCACAGG AGAGCCGAGT 
GTGAAGAAGA AGCGCAGTGC TCCCCGCAGC ATCAGCGAGC AGGAGCTGGC AGAGGTTGCA 
GATGAGTACA TGCTTTCCCT GGAGGAGAAT AAGAAGACCA AGGGTCGCCG CCAGCCCTTG 
AGCAAGCTCC CACGCCACCA CCCACTCGTG CTGCAGGAGT GCGGCAGCGA TGACGAGACT 
TCTGAGCAGC TGACCCCCGA GGAGGAGGCT GAGGAGACAG AGGCTTGGGC CAAGCCTCTG 
AGCCAGCTGT GGCAGAACCG ACCCCCGAAC TTTGAGGCTG AAAAGGAATT CAATGAGATC 
ATGGCCCAAC AGGCCCCTCA CTGTGCTGTG TGTATGATCT TCCAGACCTA CCATCAGGTG 
GAATTTGGAG CCTTCAGTCA GAGCTGTGGG GATGCTTCAG AGCCGGCTGC CCAGACTCAG 
AGGACCAAGC CACTGATCCC CGAAATGTGC TTTACCACCA CTGGCTGCAG CACAGACATC 
AATCTGTCCA CCCCGTACCT AGAGGAGGAT GGCACCAGCA TGCTAGTGTC CTGCAAGAAG 
TGCAGTGTCC GGGTCCACGC CAGTTGCTAT GGCGTCCCTC CTGCCAAGGC TTCTGAAGAA 
TGGATGTGCT CTCGATGTTC AGCCAATGCC CTGGAGGAAG ACTGCTGCTT ATGCTCGTTG 
CGTGGAGGGG CCCTGCAGAG AGCCAATGAC GACAGATGGG TTCATGTTTC ATGTGCAGTG 
GCAATTCTAG AAGCAAGGTT TGTCAACATT GCTGAAAGAA GTCCAGTGGA TGTGAGCAAA 
ATCCCTCTGC CCCGCTTCAA ACTGAAGTGT GTTTTTTGTA AGAAGCGGAG AAAACGGAAT 
GCTGGCTGCT GTGTGCAGTG CTCCCATGGC CGCTGCCCCA CTGCCTTCCA TGTGAGCTGT 
GCCCAGGCTG CTGGGGTGAT GATGCAACCC GACGACTGGC CCTTTGTTGT CTTCATCACG 
TGCTTCCGTC ACAAGATTCC CAATCTGGAG CGTGCTAAGG GAGCCTTGCT GAGCATCACG 
GCGGGCCAGA AGGTTATCAG CAAACACAAG AACGGGCGCT TCTACCAGTG TGAGGTGGTC 
AGACTCACCA CCGAGACCTT CTACGAAGTC AACTTTGACG ACGGCTCCTT CAGTGACAAC 
CTTTATCCTG AGGACATAGT GAGTCAGGAC TGTCTCCAAC TGGGGCCTCC TGCTGAAGGT 
GAAGTGGTTC AAGTCAGATG GACAGATGGC CAAGTCTATG GGGCTAAGTT TGTGGCCTCC 
CACCCCATCC AGATGTACCA GGTGGAGTTT GAGGATGGCT CGCAGCTGGT GGTTAAGAGA 
GATGATGTAT ACACACTCGA TGAAGAGCTT CCCAAGAGAG TCAAGTCTAG ACTGTCGGTG 
GCTTCAGACA TGCGCTTCAA TGAGATTTTC ACAGAGAAGG AAGTGAAGCA AGAAAAGAAG 
AGGCAACGGG TCATCAACTC GCGGTACCGG GAGGATTACA TCGAGCCAGC GCTGTACCGG 
GCCATCATGG AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The histone demethylase JMJD2A regulates the expression of BDNF and mediates neuropathic pain in mice.
Experimental cell research361(1)155-162(2017 12)
Zhou J,Wang F,Xu C,Zhou Z,Zhang W

Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin.
Scientific reports7(1)12462(2017 Sep)
Matsuura T,Miyazaki S,Miyazaki T,Tashiro F,Miyazaki JI

Maternal expression of the histone demethylase Kdm4a is crucial for pre-implantation development.
Development (Cambridge, England)144(18)3264-3277(2017 09)
Sankar A,Kooistra SM,Gonzalez JM,Ohlsson C,Poutanen M,Helin K

Inhibition of KDM4A activity as a strategy to suppress interleukin-6 production and attenuate colitis induction.
Clinical immunology (Orlando, Fla.)180120-127(2017 Jul)
Ishiguro K,Watanabe O,Nakamura M,Yamamura T,Matsushita M,Goto H,Hirooka Y

Histone Lysine Demethylases of JMJD2 or KDM4 Family are Important Epigenetic Regulators in Reward Circuitry in the Etiopathology of Depression.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology42(4)854-863(2017 Mar)
Pathak SS,Maitra S,Chakravarty S,Kumar A

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Kdm4a cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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