Ndufb6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ndufb6
Entrez Gene ID	230075
Full Name	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6
Synonyms	CI-B17,Gm137
General protein information	Preferred Names NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6 Names NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NADH-ubiquinone oxidoreductase B17 subunit complex I-B17
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 A5
Summary	This gene encodes a subunit of complex I (NADH:ubiquinone oxidoreductase) of the mitochondrial respiratory chain. This complex functions in electron transport and generation of a proton gradient across the inner mitochondrial membrane to drive ATP synthesis. Data from human cell lines suggests that the encoded subunit may be required for electron transfer activity. [provided by RefSeq, Aug 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001033305.3	NP_001028477.1	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	ndufb6	NP_957102.1
Xenopus tropicalis (tropical clawed frog)	ndufb6	NP_001016490.1
Pan troglodytes (chimpanzee)	NDUFB6	NP_001233137.1
Mus musculus (house mouse)	Ndufb6	NP_001028477.1
Rattus norvegicus (Norway rat)	Ndufb6	NP_001100116.1
Homo sapiens (human)	NDUFB6	NP_002484.1
Canis lupus familiaris (dog)	NDUFB6	NP_001239210.1
Gallus gallus (chicken)	NDUFB6	NP_001264454.1
	NDUFB6	XP_001103422.1
Bos taurus (cattle)	NDUFB6	NP_786981.1

Gene Ontology
Bibliography

Related articles in PubMed

Region-specific expression of mitochondrial complex I genes during murine brain development.
Wirtz S, Schuelke M
PloS one6(4)e18897(2011 Apr)

Respiratory active mitochondrial supercomplexes.
Ac?n-P?rez R, Fern?ndez-Silva P, Peleato ML, P?rez-Martos A, Enriquez JA
Molecular cell32(4)529-39(2008 Nov)

Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy.
Kruse SE, Watt WC, Marcinek DJ, Kapur RP, Schenkman KA, Palmiter RD
Cell metabolism7(4)312-20(2008 Apr)

MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity.
Wiley SE, Murphy AN, Ross SA, van der Geer P, Dixon JE
Proceedings of the National Academy of Sciences of the United States of America104(13)5318-23(2007 Mar)

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES, Mann M
Cell115(5)629-40(2003 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ndufb6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ndufb6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu15134	NM_001033305.3 Latest version!	Mus musculus NADH:ubiquinone oxidoreductase subunit B6 (Ndufb6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ndufb6 ( NM_001033305.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001028477.1 Mus musculus NADH:ubiquinone oxidoreductase subunit B6 (Ndufb6), mRNA.

Price & Availability↑

CloneID	OMu15134
Clone ID Related Accession (Same CDS sequence)	NM_001033305.3
Accession Version	NM_001033305.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 387bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BY233633.1, AK146762.1 and CK794473.1. On Aug 20, 2015 this sequence version replaced NM_001033305.2. ##Evidence-Data-START## Transcript exon combination :: CK794473.1, CD774546.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCAGGGT ACACGCCGGA TGAGAAGCTG CGGCTGCAGC AGCTGCGGGA GCTAAGGAGA 
CGATGGCTGA AGGACCAGGA GCTGAGTCCC CGGGAGCCCG TGTTGCCCCC GCGCAGGATG 
TGGCCCCTGG AGCGATTCTG GGATAACTTT TTGCGGGACG GGGCCGTGTG GAAGAACATG 
GTCTTTAAGG CGTACCGCTC CAGTCTCTTC GCTGTTTCTC ATGTGCTTAT ACCTATGTGG 
TTTGTTCACT ATTATGTCAA ATATCATATG GCTACTAAAC CATACACCAT TGTTAGCTCG 
AAGCCCAGGA TATTTCCAGG TGATACAATT CTGGAGACTG GAGAAGTAAT TCCACCAATG 
AGAGATTTTC CTGATCAACA TCATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028477.1
CDS	85..471
Translation	MSGYTPDEKLRLQQLRELRRRWLKDQELSPREPVLPPRRMWPLERFWDNFLRDGAVWKNMVFKAYRSSLFAVSHVLIPMWFVHYYVKYHMATKPYTIVSSKPRIFPGDTILETGEVIPPMRDFPDQHH

Target ORF information:

RefSeq Version	NM_001033305.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus NADH:ubiquinone oxidoreductase subunit B6 (Ndufb6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033305.3

ORF Insert Sequence:

ATGTCAGGGT ACACGCCGGA TGAGAAGCTG CGGCTGCAGC AGCTGCGGGA GCTAAGGAGA 
CGATGGCTGA AGGACCAGGA GCTGAGTCCC CGGGAGCCCG TGTTGCCCCC GCGCAGGATG 
TGGCCCCTGG AGCGATTCTG GGATAACTTT TTGCGGGACG GGGCCGTGTG GAAGAACATG 
GTCTTTAAGG CGTACCGCTC CAGTCTCTTC GCTGTTTCTC ATGTGCTTAT ACCTATGTGG 
TTTGTTCACT ATTATGTCAA ATATCATATG GCTACTAAAC CATACACCAT TGTTAGCTCG 
AAGCCCAGGA TATTTCCAGG TGATACAATT CTGGAGACTG GAGAAGTAAT TCCACCAATG 
AGAGATTTTC CTGATCAACA TCATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Region-specific expression of mitochondrial complex I genes during murine brain development.
PloS one6(4)e18897(2011 Apr)
Wirtz S,Schuelke M

Respiratory active mitochondrial supercomplexes.
Molecular cell32(4)529-39(2008 Nov)
Ac?n-P?rez R,Fern?ndez-Silva P,Peleato ML,P?rez-Martos A,Enriquez JA

Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy.
Cell metabolism7(4)312-20(2008 Apr)
Kruse SE,Watt WC,Marcinek DJ,Kapur RP,Schenkman KA,Palmiter RD

MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity.
Proceedings of the National Academy of Sciences of the United States of America104(13)5318-23(2007 Mar)
Wiley SE,Murphy AN,Ross SA,van der Geer P,Dixon JE

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Cell115(5)629-40(2003 Nov)
Mootha VK,Bunkenborg J,Olsen JV,Hjerrild M,Wisniewski JR,Stahl E,Bolouri MS,Ray HN,Sihag S,Kamal M,Patterson N,Lander ES,Mann M

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Ndufb6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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