Gbp7 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gbp7
Entrez Gene ID	229900
Full Name	guanylate binding protein 7
Synonyms	9830147J24Rik
General protein information	Preferred Names guanylate binding protein 7 Names guanylate binding protein 7
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3\|3 H1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001083312.2	NP_001076781.1	guanylate binding protein 7
NM_145545.4	NP_663520.2	guanylate binding protein 7

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	LOC685067	XP_003749457.1
Homo sapiens (human)	GBP7	NP_997281.2
Pan troglodytes (chimpanzee)	GBP7	XP_003949504.1
Mus musculus (house mouse)	Gbp7	NP_663520.2

Gene Ontology
Bibliography

Related articles in PubMed

A family of IFN-?-inducible 65-kD GTPases protects against bacterial infection.
Kim BH, Shenoy AR, Kumar P, Das R, Tiwari S, MacMicking JD
Science (New York, N.Y.)332(6030)717-21(2011 May)

Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.
Degrandi D, Konermann C, Beuter-Gunia C, Kresse A, W?rthner J, Kurig S, Beer S, Pfeffer K
Journal of immunology (Baltimore, Md. : 1950)179(11)7729-40(2007 Dec)

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.
Olszewski MA, Gray J, Vestal DJ
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research26(5)328-52(2006 May)

Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Okazaki N, Kikuno R, Ohara R, Inamoto S, Koseki H, Hiraoka S, Saga Y, Kitamura H, Nakagawa T, Nagase T, Ohara O, Koga H
DNA research : an international journal for rapid publication of reports on genes and genomes11(2)127-35(2004 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

findings show that at least 4 IFN-gamma-inducible Gbps--Gbp1, Gbp6, Gbp7, and Gbp10--conferred cell-autonomous immunity to listerial or mycobacterial infection within macrophages and gene-deficient animals
Title: A family of IFN-?-inducible 65-kD GTPases protects against bacterial infection.

The following Gbp7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gbp7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu02751	NM_001083312.2 Latest version!	Mus musculus guanylate binding protein 7 (Gbp7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OMu02751	NM_145545.4 Latest version!	Mus musculus guanylate binding protein 7 (Gbp7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gbp7 ( NM_001083312.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001076781.1 Mus musculus guanylate binding protein 7 (Gbp7), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu02751
Clone ID Related Accession (Same CDS sequence)	NM_001083312.2 , NM_145545.4
Accession Version	NM_001083312.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-28
Organism	Mus musculus(house mouse)
Product	guanylate binding protein 7
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC102108.12 and AK087751.1. On Nov 14, 2013 this sequence version replaced NM_001083312.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK087751.1, BC010229.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGGCATCTG GTCCCAACAT GGAGGCTCCT GTGTGCCTAG TGGAAAATGA GAATGAAGAA 
CTGAGGGTGA ACTCCAAAGC AATAAACATT CTTGAGAGGA TCACTCAGCC TGTAGTGGTG 
GTGGCCATTG TAGGACTATA CCGTACGGGA AAATCCTACT TGATGAACCG CTTGGCAGGA 
CAGAACCATG GCTTCAATCT GGGCACCACA GTTAGGTCTG AAACTAAGGG CATCTGGATG 
TGGTGTGTGC CTCACCCCAG CAAGCCCAAG TTCACACTCG TGCTTCTGGA CACGGAGGGC 
TTAGGAGATG TGGAAAAGGG TGACCCTAAG AATGACTCGT GGATCTTCGC CCTGGCTGTG 
CTTCTGAGCA GCACCTTTGT CTACAACAGC ATGAGCACCA TCAACCACCA GGCCCTGGAG 
CAGCTGCACT ATGTCACAGA ACTGACAGAG CGGATCAGGG CAAAGTCCAC TTCACGGTCT 
GAAGAAGTGG ATGACTCTGA TGAGTTTGTA AGTTTCTTTC CAGATTTTAT CTGGACTGTT 
CGAGATTTCG TTCTGGAGCT GAAGTTAGAG GGACGTGTCA TCACAGCAGA CGAGTACCTA 
GAAAATGCCC TGAAGCTGAT CCCAGGCATG AGTATCAAAG CCCAGAAAGC TAACTTGCCT 
AGGGAATGCA TCAGGCACTT CTTTCCAAGA CGGAAGTGCT TTGTCTTTGA TCGACCTACA 
AAAGACAAAG AACTTTTAGT GCATGTTGAG GAAATGCCAG AGGACCAGTT GGATCACAGT 
TTCCAAGTGC AGTCAAAAGA ATTCTGTTCC TACATCTTCT CCAATTCGAA GGCCAAGACC 
TTGAAAGAGG GAATCGTTGT CAATGGAAAC CGACTGGCGA CTCTGGTGAC GACCTACGTG 
GATGCTATCA ATAGTGGAGA CGTGCCGTGT TTAGAGAACG CAGTAACAAC CCTGGCCCAG 
CGTGAGAACT CCATAGCTGT GCAGAAGGCA GCTGACCACT ACAGTGAGCA GATGGCCCAG 
CGAATGAGGC TCCCCACAGA CACGCTCCAG GAGCTGCTGA CTGTGCATAC AGCCTGTGAG 
AAGGAAGCCA TTGCTGTCTT CATGGAGCAC TCCTTCAAGG ATGAGAATCA GCAATTCCAG 
AAGAACTTGG TGGTCACCAT AGAGGAAAAA AAGGAAGATT TCCTGCGACA GAATGAAGCA 
GCGTCTCTCA GTCACTGCCA GGCTGAGCTG GACAAGCTCT CAGAGTCCCT GAGGGAGAGC 
ATCTCACGTG GAGTTTTCTC TGTTCCTGGG GGTCACAGGC TCTACTTAGA GGCCAGGAAG 
AAGGTTGAAC AGGACTATGA GCGAGTGCCC AGGAAGGGAG TGAAGGCAAA TCATGTCCTT 
CAGAGCTTCC TACAGTCACA GATTTCCATT GAGGACTCCA TTATGCAGTC AGACAAAGCC 
CTCACTGATG GCCAGAAGGC CATGGAAGCT GAGCGAGCTC AGAAGGAGGC AGCTGAGAAG 
GAGCAGGAGC TACTAAGACA GAAACAGAAG GAGCTGCAGC AGGTGATGGA AGCTCAAGAG 
AGAAGCTACA AGGAAAATGT GGCCCAGCTG CACGAGAAGA TGGAGACAGA AAGGAAGAAC 
ATCCTGAGAG AGCAAGAGGT GAAGCTGGAA CACAAGTTGA AGATTCAAAA AGACATGCTT 
AATGAGGGAT TTAAAAGGAA ATGTGAAGCA ATGGATTTGG AGATAAGTCA ACTACAAAAA 
GAGATTCAAC TAAATAAGGA GAAGAATAGC TCATTGGGTG CAAAAATCCT TGATGGGTTT 
GGAGATGTAT TAATTTCAGT AGTGCCTGGT TCTGGTAAGT ACTTTGGTCT AGGGTTGAAA 
ATATTAAGCA GCCAAATGAA TCAGACACAG AATTCAGACA AAGTTAGAAA ACTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001076781.1
CDS	111..2027
Translation	MASGPNMEAPVCLVENENEELRVNSKAINILERITQPVVVVAIVGLYRTGKSYLMNRLAGQNHGFNLGTTVRSETKGIWMWCVPHPSKPKFTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLSSTFVYNSMSTINHQALEQLHYVTELTERIRAKSTSRSEEVDDSDEFVSFFPDFIWTVRDFVLELKLEGRVITADEYLENALKLIPGMSIKAQKANLPRECIRHFFPRRKCFVFDRPTKDKELLVHVEEMPEDQLDHSFQVQSKEFCSYIFSNSKAKTLKEGIVVNGNRLATLVTTYVDAINSGDVPCLENAVTTLAQRENSIAVQKAADHYSEQMAQRMRLPTDTLQELLTVHTACEKEAIAVFMEHSFKDENQQFQKNLVVTIEEKKEDFLRQNEAASLSHCQAELDKLSESLRESISRGVFSVPGGHRLYLEARKKVEQDYERVPRKGVKANHVLQSFLQSQISIEDSIMQSDKALTDGQKAMEAERAQKEAAEKEQELLRQKQKELQQVMEAQERSYKENVAQLHEKMETERKNILREQEVKLEHKLKIQKDMLNEGFKRKCEAMDLEISQLQKEIQLNKEKNSSLGAKILDGFGDVLISVVPGSGKYFGLGLKILSSQMNQTQNSDKVRKL

Target ORF information:

RefSeq Version	NM_001083312.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanylate binding protein 7 (Gbp7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001083312.2

ORF Insert Sequence:

ATGGCATCTG GTCCCAACAT GGAGGCTCCT GTGTGCCTAG TGGAAAATGA GAATGAAGAA 
CTGAGGGTGA ACTCCAAAGC AATAAACATT CTTGAGAGGA TCACTCAGCC TGTAGTGGTG 
GTGGCCATTG TAGGACTATA CCGTACGGGA AAATCCTACT TGATGAACCG CTTGGCAGGA 
CAGAACCATG GCTTCAATCT GGGCACCACA GTTAGGTCTG AAACTAAGGG CATCTGGATG 
TGGTGTGTGC CTCACCCCAG CAAGCCCAAG TTCACACTCG TGCTTCTGGA CACGGAGGGC 
TTAGGAGATG TGGAAAAGGG TGACCCTAAG AATGACTCGT GGATCTTCGC CCTGGCTGTG 
CTTCTGAGCA GCACCTTTGT CTACAACAGC ATGAGCACCA TCAACCACCA GGCCCTGGAG 
CAGCTGCACT ATGTCACAGA ACTGACAGAG CGGATCAGGG CAAAGTCCAC TTCACGGTCT 
GAAGAAGTGG ATGACTCTGA TGAGTTTGTA AGTTTCTTTC CAGATTTTAT CTGGACTGTT 
CGAGATTTCG TTCTGGAGCT GAAGTTAGAG GGACGTGTCA TCACAGCAGA CGAGTACCTA 
GAAAATGCCC TGAAGCTGAT CCCAGGCATG AGTATCAAAG CCCAGAAAGC TAACTTGCCT 
AGGGAATGCA TCAGGCACTT CTTTCCAAGA CGGAAGTGCT TTGTCTTTGA TCGACCTACA 
AAAGACAAAG AACTTTTAGT GCATGTTGAG GAAATGCCAG AGGACCAGTT GGATCACAGT 
TTCCAAGTGC AGTCAAAAGA ATTCTGTTCC TACATCTTCT CCAATTCGAA GGCCAAGACC 
TTGAAAGAGG GAATCGTTGT CAATGGAAAC CGACTGGCGA CTCTGGTGAC GACCTACGTG 
GATGCTATCA ATAGTGGAGA CGTGCCGTGT TTAGAGAACG CAGTAACAAC CCTGGCCCAG 
CGTGAGAACT CCATAGCTGT GCAGAAGGCA GCTGACCACT ACAGTGAGCA GATGGCCCAG 
CGAATGAGGC TCCCCACAGA CACGCTCCAG GAGCTGCTGA CTGTGCATAC AGCCTGTGAG 
AAGGAAGCCA TTGCTGTCTT CATGGAGCAC TCCTTCAAGG ATGAGAATCA GCAATTCCAG 
AAGAACTTGG TGGTCACCAT AGAGGAAAAA AAGGAAGATT TCCTGCGACA GAATGAAGCA 
GCGTCTCTCA GTCACTGCCA GGCTGAGCTG GACAAGCTCT CAGAGTCCCT GAGGGAGAGC 
ATCTCACGTG GAGTTTTCTC TGTTCCTGGG GGTCACAGGC TCTACTTAGA GGCCAGGAAG 
AAGGTTGAAC AGGACTATGA GCGAGTGCCC AGGAAGGGAG TGAAGGCAAA TCATGTCCTT 
CAGAGCTTCC TACAGTCACA GATTTCCATT GAGGACTCCA TTATGCAGTC AGACAAAGCC 
CTCACTGATG GCCAGAAGGC CATGGAAGCT GAGCGAGCTC AGAAGGAGGC AGCTGAGAAG 
GAGCAGGAGC TACTAAGACA GAAACAGAAG GAGCTGCAGC AGGTGATGGA AGCTCAAGAG 
AGAAGCTACA AGGAAAATGT GGCCCAGCTG CACGAGAAGA TGGAGACAGA AAGGAAGAAC 
ATCCTGAGAG AGCAAGAGGT GAAGCTGGAA CACAAGTTGA AGATTCAAAA AGACATGCTT 
AATGAGGGAT TTAAAAGGAA ATGTGAAGCA ATGGATTTGG AGATAAGTCA ACTACAAAAA 
GAGATTCAAC TAAATAAGGA GAAGAATAGC TCATTGGGTG CAAAAATCCT TGATGGGTTT 
GGAGATGTAT TAATTTCAGT AGTGCCTGGT TCTGGTAAGT ACTTTGGTCT AGGGTTGAAA 
ATATTAAGCA GCCAAATGAA TCAGACACAG AATTCAGACA AAGTTAGAAA ACTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gbp7 ( NM_145545.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_663520.2 Mus musculus guanylate binding protein 7 (Gbp7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu02751
Clone ID Related Accession (Same CDS sequence)	NM_001083312.2 , NM_145545.4
Accession Version	NM_145545.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-25
Organism	Mus musculus(house mouse)
Product	guanylate binding protein 7
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC102108.12 and AK036666.1. On Nov 14, 2013 this sequence version replaced NM_145545.3. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK036666.1, BK005760.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134, SAMN01164135 [ECO:0000348] ##Evidence-Data-END##

ATGGCATCTG GTCCCAACAT GGAGGCTCCT GTGTGCCTAG TGGAAAATGA GAATGAAGAA 
CTGAGGGTGA ACTCCAAAGC AATAAACATT CTTGAGAGGA TCACTCAGCC TGTAGTGGTG 
GTGGCCATTG TAGGACTATA CCGTACGGGA AAATCCTACT TGATGAACCG CTTGGCAGGA 
CAGAACCATG GCTTCAATCT GGGCACCACA GTTAGGTCTG AAACTAAGGG CATCTGGATG 
TGGTGTGTGC CTCACCCCAG CAAGCCCAAG TTCACACTCG TGCTTCTGGA CACGGAGGGC 
TTAGGAGATG TGGAAAAGGG TGACCCTAAG AATGACTCGT GGATCTTCGC CCTGGCTGTG 
CTTCTGAGCA GCACCTTTGT CTACAACAGC ATGAGCACCA TCAACCACCA GGCCCTGGAG 
CAGCTGCACT ATGTCACAGA ACTGACAGAG CGGATCAGGG CAAAGTCCAC TTCACGGTCT 
GAAGAAGTGG ATGACTCTGA TGAGTTTGTA AGTTTCTTTC CAGATTTTAT CTGGACTGTT 
CGAGATTTCG TTCTGGAGCT GAAGTTAGAG GGACGTGTCA TCACAGCAGA CGAGTACCTA 
GAAAATGCCC TGAAGCTGAT CCCAGGCATG AGTATCAAAG CCCAGAAAGC TAACTTGCCT 
AGGGAATGCA TCAGGCACTT CTTTCCAAGA CGGAAGTGCT TTGTCTTTGA TCGACCTACA 
AAAGACAAAG AACTTTTAGT GCATGTTGAG GAAATGCCAG AGGACCAGTT GGATCACAGT 
TTCCAAGTGC AGTCAAAAGA ATTCTGTTCC TACATCTTCT CCAATTCGAA GGCCAAGACC 
TTGAAAGAGG GAATCGTTGT CAATGGAAAC CGACTGGCGA CTCTGGTGAC GACCTACGTG 
GATGCTATCA ATAGTGGAGA CGTGCCGTGT TTAGAGAACG CAGTAACAAC CCTGGCCCAG 
CGTGAGAACT CCATAGCTGT GCAGAAGGCA GCTGACCACT ACAGTGAGCA GATGGCCCAG 
CGAATGAGGC TCCCCACAGA CACGCTCCAG GAGCTGCTGA CTGTGCATAC AGCCTGTGAG 
AAGGAAGCCA TTGCTGTCTT CATGGAGCAC TCCTTCAAGG ATGAGAATCA GCAATTCCAG 
AAGAACTTGG TGGTCACCAT AGAGGAAAAA AAGGAAGATT TCCTGCGACA GAATGAAGCA 
GCGTCTCTCA GTCACTGCCA GGCTGAGCTG GACAAGCTCT CAGAGTCCCT GAGGGAGAGC 
ATCTCACGTG GAGTTTTCTC TGTTCCTGGG GGTCACAGGC TCTACTTAGA GGCCAGGAAG 
AAGGTTGAAC AGGACTATGA GCGAGTGCCC AGGAAGGGAG TGAAGGCAAA TCATGTCCTT 
CAGAGCTTCC TACAGTCACA GATTTCCATT GAGGACTCCA TTATGCAGTC AGACAAAGCC 
CTCACTGATG GCCAGAAGGC CATGGAAGCT GAGCGAGCTC AGAAGGAGGC AGCTGAGAAG 
GAGCAGGAGC TACTAAGACA GAAACAGAAG GAGCTGCAGC AGGTGATGGA AGCTCAAGAG 
AGAAGCTACA AGGAAAATGT GGCCCAGCTG CACGAGAAGA TGGAGACAGA AAGGAAGAAC 
ATCCTGAGAG AGCAAGAGGT GAAGCTGGAA CACAAGTTGA AGATTCAAAA AGACATGCTT 
AATGAGGGAT TTAAAAGGAA ATGTGAAGCA ATGGATTTGG AGATAAGTCA ACTACAAAAA 
GAGATTCAAC TAAATAAGGA GAAGAATAGC TCATTGGGTG CAAAAATCCT TGATGGGTTT 
GGAGATGTAT TAATTTCAGT AGTGCCTGGT TCTGGTAAGT ACTTTGGTCT AGGGTTGAAA 
ATATTAAGCA GCCAAATGAA TCAGACACAG AATTCAGACA AAGTTAGAAA ACTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_663520.2
CDS	129..2045
Translation	MASGPNMEAPVCLVENENEELRVNSKAINILERITQPVVVVAIVGLYRTGKSYLMNRLAGQNHGFNLGTTVRSETKGIWMWCVPHPSKPKFTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLSSTFVYNSMSTINHQALEQLHYVTELTERIRAKSTSRSEEVDDSDEFVSFFPDFIWTVRDFVLELKLEGRVITADEYLENALKLIPGMSIKAQKANLPRECIRHFFPRRKCFVFDRPTKDKELLVHVEEMPEDQLDHSFQVQSKEFCSYIFSNSKAKTLKEGIVVNGNRLATLVTTYVDAINSGDVPCLENAVTTLAQRENSIAVQKAADHYSEQMAQRMRLPTDTLQELLTVHTACEKEAIAVFMEHSFKDENQQFQKNLVVTIEEKKEDFLRQNEAASLSHCQAELDKLSESLRESISRGVFSVPGGHRLYLEARKKVEQDYERVPRKGVKANHVLQSFLQSQISIEDSIMQSDKALTDGQKAMEAERAQKEAAEKEQELLRQKQKELQQVMEAQERSYKENVAQLHEKMETERKNILREQEVKLEHKLKIQKDMLNEGFKRKCEAMDLEISQLQKEIQLNKEKNSSLGAKILDGFGDVLISVVPGSGKYFGLGLKILSSQMNQTQNSDKVRKL

Target ORF information:

RefSeq Version	NM_145545.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanylate binding protein 7 (Gbp7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145545.4

ORF Insert Sequence:

ATGGCATCTG GTCCCAACAT GGAGGCTCCT GTGTGCCTAG TGGAAAATGA GAATGAAGAA 
CTGAGGGTGA ACTCCAAAGC AATAAACATT CTTGAGAGGA TCACTCAGCC TGTAGTGGTG 
GTGGCCATTG TAGGACTATA CCGTACGGGA AAATCCTACT TGATGAACCG CTTGGCAGGA 
CAGAACCATG GCTTCAATCT GGGCACCACA GTTAGGTCTG AAACTAAGGG CATCTGGATG 
TGGTGTGTGC CTCACCCCAG CAAGCCCAAG TTCACACTCG TGCTTCTGGA CACGGAGGGC 
TTAGGAGATG TGGAAAAGGG TGACCCTAAG AATGACTCGT GGATCTTCGC CCTGGCTGTG 
CTTCTGAGCA GCACCTTTGT CTACAACAGC ATGAGCACCA TCAACCACCA GGCCCTGGAG 
CAGCTGCACT ATGTCACAGA ACTGACAGAG CGGATCAGGG CAAAGTCCAC TTCACGGTCT 
GAAGAAGTGG ATGACTCTGA TGAGTTTGTA AGTTTCTTTC CAGATTTTAT CTGGACTGTT 
CGAGATTTCG TTCTGGAGCT GAAGTTAGAG GGACGTGTCA TCACAGCAGA CGAGTACCTA 
GAAAATGCCC TGAAGCTGAT CCCAGGCATG AGTATCAAAG CCCAGAAAGC TAACTTGCCT 
AGGGAATGCA TCAGGCACTT CTTTCCAAGA CGGAAGTGCT TTGTCTTTGA TCGACCTACA 
AAAGACAAAG AACTTTTAGT GCATGTTGAG GAAATGCCAG AGGACCAGTT GGATCACAGT 
TTCCAAGTGC AGTCAAAAGA ATTCTGTTCC TACATCTTCT CCAATTCGAA GGCCAAGACC 
TTGAAAGAGG GAATCGTTGT CAATGGAAAC CGACTGGCGA CTCTGGTGAC GACCTACGTG 
GATGCTATCA ATAGTGGAGA CGTGCCGTGT TTAGAGAACG CAGTAACAAC CCTGGCCCAG 
CGTGAGAACT CCATAGCTGT GCAGAAGGCA GCTGACCACT ACAGTGAGCA GATGGCCCAG 
CGAATGAGGC TCCCCACAGA CACGCTCCAG GAGCTGCTGA CTGTGCATAC AGCCTGTGAG 
AAGGAAGCCA TTGCTGTCTT CATGGAGCAC TCCTTCAAGG ATGAGAATCA GCAATTCCAG 
AAGAACTTGG TGGTCACCAT AGAGGAAAAA AAGGAAGATT TCCTGCGACA GAATGAAGCA 
GCGTCTCTCA GTCACTGCCA GGCTGAGCTG GACAAGCTCT CAGAGTCCCT GAGGGAGAGC 
ATCTCACGTG GAGTTTTCTC TGTTCCTGGG GGTCACAGGC TCTACTTAGA GGCCAGGAAG 
AAGGTTGAAC AGGACTATGA GCGAGTGCCC AGGAAGGGAG TGAAGGCAAA TCATGTCCTT 
CAGAGCTTCC TACAGTCACA GATTTCCATT GAGGACTCCA TTATGCAGTC AGACAAAGCC 
CTCACTGATG GCCAGAAGGC CATGGAAGCT GAGCGAGCTC AGAAGGAGGC AGCTGAGAAG 
GAGCAGGAGC TACTAAGACA GAAACAGAAG GAGCTGCAGC AGGTGATGGA AGCTCAAGAG 
AGAAGCTACA AGGAAAATGT GGCCCAGCTG CACGAGAAGA TGGAGACAGA AAGGAAGAAC 
ATCCTGAGAG AGCAAGAGGT GAAGCTGGAA CACAAGTTGA AGATTCAAAA AGACATGCTT 
AATGAGGGAT TTAAAAGGAA ATGTGAAGCA ATGGATTTGG AGATAAGTCA ACTACAAAAA 
GAGATTCAAC TAAATAAGGA GAAGAATAGC TCATTGGGTG CAAAAATCCT TGATGGGTTT 
GGAGATGTAT TAATTTCAGT AGTGCCTGGT TCTGGTAAGT ACTTTGGTCT AGGGTTGAAA 
ATATTAAGCA GCCAAATGAA TCAGACACAG AATTCAGACA AAGTTAGAAA ACTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A family of IFN-?-inducible 65-kD GTPases protects against bacterial infection.
Science (New York, N.Y.)332(6030)717-21(2011 May)
Kim BH,Shenoy AR,Kumar P,Das R,Tiwari S,MacMicking JD

Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.
Journal of immunology (Baltimore, Md. : 1950)179(11)7729-40(2007 Dec)
Degrandi D,Konermann C,Beuter-Gunia C,Kresse A,W?rthner J,Kurig S,Beer S,Pfeffer K

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research26(5)328-52(2006 May)
Olszewski MA,Gray J,Vestal DJ

Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
DNA research : an international journal for rapid publication of reports on genes and genomes11(2)127-35(2004 Apr)
Okazaki N,Kikuno R,Ohara R,Inamoto S,Koseki H,Hiraoka S,Saga Y,Kitamura H,Nakagawa T,Nagase T,Ohara O,Koga H

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Gbp7 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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