Vps18 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Vps18
Entrez Gene ID	228545
Full Name	VPS18 CORVET/HOPS core subunit
Synonyms	9930024E13Rik
General protein information	Preferred Names VPS18 CORVET/HOPS core subunit Names vacuolar protein sorting-associated protein 18 homolog vacuolar protein sorting 18
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 E5

mRNA and Protein(s)

mRNA	Protein	Name
NM_172269.3	NP_758473.3	vacuolar protein sorting-associated protein 18 homolog

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000983	XP_560205.4
Magnaporthe oryzae (rice blast fungus)	MGG_06325	XP_003717259.1
Schizosaccharomyces pombe (fission yeast)	pep3	NP_588498.1
Arabidopsis thaliana (thale cress)	AT1G12470	NP_172709.2
Homo sapiens (human)	VPS18	NP_065908.1
Mus musculus (house mouse)	Vps18	NP_758473.3
Rattus norvegicus (Norway rat)	Vps18	NP_001099969.1
Gallus gallus (chicken)	VPS18	NP_001186584.1
Drosophila melanogaster (fruit fly)	dor	NP_477286.2
Xenopus tropicalis (tropical clawed frog)	vps18	NP_001121454.1
	VPS18	XP_001099146.1
Canis lupus familiaris (dog)	VPS18	XP_544627.3
Oryza sativa (rice)	Os08g0178100	NP_001061126.1
Pan troglodytes (chimpanzee)	VPS18	XP_523187.2
Bos taurus (cattle)	VPS18	NP_001093850.1
Danio rerio (zebrafish)	vps18	NP_775352.2
Neurospora crassa	NCU06183	XP_962995.2

Gene Ontology
Bibliography

Related articles in PubMed

Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.
Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen JK, G?mez-Gal?n M, Sopova E, Joodmardi E, Yoshitake T, Deng Q, Kehr J, Ericson J, Svenningsson P, Shupliakov O, Perlmann T
Nature neuroscience18(6)826-35(2015 Jun)

Mammalian CORVET is required for fusion and conversion of distinct early endosome subpopulations.
Perini ED, Schaefer R, St?ter M, Kalaidzidis Y, Zerial M
Traffic (Copenhagen, Denmark)15(12)1366-89(2014 Dec)

UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs.
Pirooz SD, He S, Zhang T, Zhang X, Zhao Z, Oh S, O'Connell D, Khalilzadeh P, Amini-Bavil-Olyaee S, Farzan M, Liang C
Proceedings of the National Academy of Sciences of the United States of America111(7)2716-21(2014 Feb)

Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes.
Peng C, Ye J, Yan S, Kong S, Shen Y, Li C, Li Q, Zheng Y, Deng K, Xu T, Tao W
The Journal of biological chemistry287(39)32861-73(2012 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

important roles of Vps18 in neuron survival and migration, which are disrupted in multiple neural disorders.
Title: Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes.

Vps18 deficiency severely blocks the dendrite development of Pukinje cells but not cerebral cortical neurons.
Title: Vps18 deficiency inhibits dendritogenesis in Purkinje cells by blocking the lysosomal degradation of Lysyl Oxidase.

The following Vps18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Vps18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu19287	NM_172269.3 Latest version!	Mus musculus VPS18 CORVET/HOPS core subunit (Vps18), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Vps18 ( NM_172269.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_758473.3 Mus musculus VPS18 CORVET/HOPS core subunit (Vps18), mRNA.

Price & Availability↑

CloneID	OMu19287
Clone ID Related Accession (Same CDS sequence)	NM_172269.3
Accession Version	NM_172269.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2922bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-22
Organism	Mus musculus(house mouse)
Product	vacuolar protein sorting-associated protein 18 homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL929318.11, AK036915.1 and AK033333.1. On Jul 24, 2009 this sequence version replaced NM_172269.2. ##Evidence-Data-START## Transcript exon combination :: AK033333.1, SRR1660817.79750.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCGTCCA TCCTGGATGA GTACGAGGAC TCATTGTCCC GCTCGGCCGT CTTGCAGACT 
GGTTGCCCTA GCGTGGGCAT CCCCCATTCT GGGTATGTAA GTGCCCACCT GGAGAAGGAG 
GTGCCCATCT TCACCAAGCA GCGGGTTGAC TTCACCCCCT CGGAGCGGAT CACTAGCCTC 
GTGGTCTCCT GCAATCAGCT CTGCATGAGC CTGGGCAAGG ATACACTGCT CCGCATTGAC 
TTGGGCAAGG CAAGTGAGCC CAACCGTGTG GAACTGGGGC GCAAGGACGA CGCCAAAGTC 
CACAAGATGT TCCTGGACCA TACTGGCTCT CATCTGCTGG TTGCGCTGAG TAGCACCGAG 
GTCCTTTACA TGAACCGCAA TGGACAGAAG GCCCGGCCCC TGGCTCGCTG GAAGGGACAG 
CTGGTGGAGA GTGTGGGATG GAACAAGGCC ATGGGCAACG AGAGCAGCAC CGGCCCCATC 
CTGGTCGGCA CAGCTCAAGG ACAGATCTTT GAAGCAGAGC TCTCAGCTAG CGAGGGTGGC 
CTCTTTGGCC CTGCCCCAGA TCTCTACTTC CGTCCACTGT ATGTGTTAAA TGAAGAAGGG 
GGTCCAGCCC CTGTGTGCTC CCTCGAGGCT GAGCGTGGCC CCGATGGCCG AGGCTTTGTC 
ATTGCCACCA CTCGGCAGCG CCTCTTCCAG TTCATAGGCC GAGCTGTGGA AGATACTGAA 
GCCCAGGGCT TCGCAGGACT CTTTGCTGCC TATACAGACC ACCCGCCCCC ATTCCGTGAG 
TTTCCTAGCA ATTTGGGGTA TAGTGAGTTG GCTTTCTATA CCCCTAAGTT ACGCTCGGCA 
CCTCGCGCCT TTGCCTGGAT GATGGGAGAT GGAGTGCTGT ATGGCTCACT GGACTGCGGG 
CGTCCTGACT CGCTGCTGAG TGAGGAGCGA GTGTGGGAAT ACCCAGCGGG GGTTGGTCCT 
GGGGCCAATC CACCCTTAGC CATCGTCCTG ACCCAGTTCC ATTTCCTACT GCTGCTGGCC 
GACCGGGTGG AGGCTGTGTG CACGCTAACA GGGCAGGTGG TGCTACGGGA TCACTTCCTG 
GAGAAGTTTG GACCACTGAG GCACATGGTG AAGGACTCAT CCACAGGCCA CCTATGGGCC 
TACACTGAGC GTGCGGTCTT CCGCTACCAT GTGCAACGTG AGGCACGGGA TGTCTGGCGC 
ACCTACTTGG ACATGAACCG CTTTGACCTG GCCAAAGAGT ATTGTAGAGA GCGGCCTGAT 
TGCCTGGACA CGGTCCTGGC CCGAGAGGCT GATTTCTGTT TTCGTCAGCA TCGCTACCTG 
GAGAGCGCCC GCTGCTACGC GCTGACCCAG AGCTATTTTG AGGAGATTGC CCTCAAGTTC 
TTGGAGGCCC GGCAAGAGGA GGCGCTGGCC GAGTTTCTTC AGCGGAAACT GGCCGGCTTG 
AAGCCGACGG AGCGTACCCA GGCCACACTG CTGACCACTT GGCTGACAGA GCTCTACCTG 
AGCCGCCTGG GTGCTCTGCA GGGTGACCCA GATGCTCTGA CTCTCTACCG GGACACACGG 
GAGTGTTTCC GTACTTTTCT CAGTAGCCCT CGGCACAAAG AGTGGCTCTT TGCCAGCCGG 
GCCTCTATCC ACGAGCTGCT CGCCAGTCAC GGAGACACAG AGCACATGGT GTATTTTGCA 
GTGATCATGC AGGACTATGA ACGGGTGGTC GCATACCACT GCCAGCATGA GGCTTACGAG 
GAGGCCCTGG CTGTGCTTGC CCGCCACCGG GACCCCCAGC TCTTCTACAA ATTCTCCCCC 
ATTCTCATCC GCCACATCCC CCGCCAGCTC GTAGACGCCT GGATTGAGAT GGGCAGCCGG 
CTGGATGCTC GGCAGCTCAT CCCTGCCCTG GTGAACTACA GCCAGGGCGG TGAGGCCCAG 
CAGGTGAGCC AGGCCATCCG CTACATGGAA TTCTGCGTGA ATGTGCTCGG TGAGACGGAG 
CAGGCCATTC ACAACTACCT GCTGTCCCTG TATGCCCGTG GCCAGCCAGC CTCACTTCTG 
GCATACCTGG AACAAGCTGG GGCCAGCCCG CACCGTGTAC ATTATGATCT CAAATATGCA 
CTTCGACTTT GTGCTGAGCA CGGCCACCAC CGCGCCTGCG TCCATGTCTA TAAGGTGTTG 
GAGCTATATG AGGAGGCTGT GGACCTGGCC CTGCAGGTGG ATGTGGACCT GGCCAAGCAG 
TGTGCAGACT TGCCGGAGGA GGATGAGGAA CTTCGCAAGA AACTATGGCT CAAGATCGCC 
CGGCACGTGG TGCAGGAGGA AGAAGACGTC CAGACAGCCA TGGCCTGCTT GGCCAGCTGC 
CCCTTGCTCA AGATCGAGGA TGTGCTGCCC TTCTTCCCTG ACTTTGTCAC CATCGACCAC 
TTCAAGGAGG CAATCTGTAG TTCCCTGAAG GCCTACAACC ACCACATCCA GGAGCTGCAG 
CGCGAGATGG AAGAAGCCAC AGCCAGTGCC CAGCGCATCC GACGAGACTT GCAGGAGCTC 
CGAGGCCGCT ATGGCACCGT GGAGCCCCAG GACAAATGCT CCACCTGTGA CTTTCCTTTG 
CTCAACCGAC CCTTTTACCT GTTTCTCTGT GGCCACATGT TTCACGCTGA CTGTCTCCTA 
CAGGCTGTGC GGCCCGGCCT CCCTGCCTAC AAGCAGGCCA GACTTGAGGA ACTGCAGCGC 
AAGCTTGGGG CGGCGCCTCC TCCGACCAAA GGCTCCGTGA AGGCCAAGGA GGCAGAAGCT 
GGGGCTGCAG CGGTGGGGCC CAGTCGGGAG CAGCTCAAGG CTGACCTGGA TGAGCTGGTG 
GCTGCTGAGT GTGTGTACTG TGGGGAGCTG ATGATTCGGT CTATCGACCG GCCCTTCATT 
GATCCGCAGC GCTATGAGGA GGAGCACCTC AGCTGGCTAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_758473.3
CDS	299..3220
Translation	MASILDEYEDSLSRSAVLQTGCPSVGIPHSGYVSAHLEKEVPIFTKQRVDFTPSERITSLVVSCNQLCMSLGKDTLLRIDLGKASEPNRVELGRKDDAKVHKMFLDHTGSHLLVALSSTEVLYMNRNGQKARPLARWKGQLVESVGWNKAMGNESSTGPILVGTAQGQIFEAELSASEGGLFGPAPDLYFRPLYVLNEEGGPAPVCSLEAERGPDGRGFVIATTRQRLFQFIGRAVEDTEAQGFAGLFAAYTDHPPPFREFPSNLGYSELAFYTPKLRSAPRAFAWMMGDGVLYGSLDCGRPDSLLSEERVWEYPAGVGPGANPPLAIVLTQFHFLLLLADRVEAVCTLTGQVVLRDHFLEKFGPLRHMVKDSSTGHLWAYTERAVFRYHVQREARDVWRTYLDMNRFDLAKEYCRERPDCLDTVLAREADFCFRQHRYLESARCYALTQSYFEEIALKFLEARQEEALAEFLQRKLAGLKPTERTQATLLTTWLTELYLSRLGALQGDPDALTLYRDTRECFRTFLSSPRHKEWLFASRASIHELLASHGDTEHMVYFAVIMQDYERVVAYHCQHEAYEEALAVLARHRDPQLFYKFSPILIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGEAQQVSQAIRYMEFCVNVLGETEQAIHNYLLSLYARGQPASLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASCPLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQELRGRYGTVEPQDKCSTCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQRKLGAAPPPTKGSVKAKEAEAGAAAVGPSREQLKADLDELVAAECVYCGELMIRSIDRPFIDPQRYEEEHLSWL

Target ORF information:

RefSeq Version	NM_172269.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus VPS18 CORVET/HOPS core subunit (Vps18), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172269.3

ORF Insert Sequence:

ATGGCGTCCA TCCTGGATGA GTACGAGGAC TCATTGTCCC GCTCGGCCGT CTTGCAGACT 
GGTTGCCCTA GCGTGGGCAT CCCCCATTCT GGGTATGTAA GTGCCCACCT GGAGAAGGAG 
GTGCCCATCT TCACCAAGCA GCGGGTTGAC TTCACCCCCT CGGAGCGGAT CACTAGCCTC 
GTGGTCTCCT GCAATCAGCT CTGCATGAGC CTGGGCAAGG ATACACTGCT CCGCATTGAC 
TTGGGCAAGG CAAGTGAGCC CAACCGTGTG GAACTGGGGC GCAAGGACGA CGCCAAAGTC 
CACAAGATGT TCCTGGACCA TACTGGCTCT CATCTGCTGG TTGCGCTGAG TAGCACCGAG 
GTCCTTTACA TGAACCGCAA TGGACAGAAG GCCCGGCCCC TGGCTCGCTG GAAGGGACAG 
CTGGTGGAGA GTGTGGGATG GAACAAGGCC ATGGGCAACG AGAGCAGCAC CGGCCCCATC 
CTGGTCGGCA CAGCTCAAGG ACAGATCTTT GAAGCAGAGC TCTCAGCTAG CGAGGGTGGC 
CTCTTTGGCC CTGCCCCAGA TCTCTACTTC CGTCCACTGT ATGTGTTAAA TGAAGAAGGG 
GGTCCAGCCC CTGTGTGCTC CCTCGAGGCT GAGCGTGGCC CCGATGGCCG AGGCTTTGTC 
ATTGCCACCA CTCGGCAGCG CCTCTTCCAG TTCATAGGCC GAGCTGTGGA AGATACTGAA 
GCCCAGGGCT TCGCAGGACT CTTTGCTGCC TATACAGACC ACCCGCCCCC ATTCCGTGAG 
TTTCCTAGCA ATTTGGGGTA TAGTGAGTTG GCTTTCTATA CCCCTAAGTT ACGCTCGGCA 
CCTCGCGCCT TTGCCTGGAT GATGGGAGAT GGAGTGCTGT ATGGCTCACT GGACTGCGGG 
CGTCCTGACT CGCTGCTGAG TGAGGAGCGA GTGTGGGAAT ACCCAGCGGG GGTTGGTCCT 
GGGGCCAATC CACCCTTAGC CATCGTCCTG ACCCAGTTCC ATTTCCTACT GCTGCTGGCC 
GACCGGGTGG AGGCTGTGTG CACGCTAACA GGGCAGGTGG TGCTACGGGA TCACTTCCTG 
GAGAAGTTTG GACCACTGAG GCACATGGTG AAGGACTCAT CCACAGGCCA CCTATGGGCC 
TACACTGAGC GTGCGGTCTT CCGCTACCAT GTGCAACGTG AGGCACGGGA TGTCTGGCGC 
ACCTACTTGG ACATGAACCG CTTTGACCTG GCCAAAGAGT ATTGTAGAGA GCGGCCTGAT 
TGCCTGGACA CGGTCCTGGC CCGAGAGGCT GATTTCTGTT TTCGTCAGCA TCGCTACCTG 
GAGAGCGCCC GCTGCTACGC GCTGACCCAG AGCTATTTTG AGGAGATTGC CCTCAAGTTC 
TTGGAGGCCC GGCAAGAGGA GGCGCTGGCC GAGTTTCTTC AGCGGAAACT GGCCGGCTTG 
AAGCCGACGG AGCGTACCCA GGCCACACTG CTGACCACTT GGCTGACAGA GCTCTACCTG 
AGCCGCCTGG GTGCTCTGCA GGGTGACCCA GATGCTCTGA CTCTCTACCG GGACACACGG 
GAGTGTTTCC GTACTTTTCT CAGTAGCCCT CGGCACAAAG AGTGGCTCTT TGCCAGCCGG 
GCCTCTATCC ACGAGCTGCT CGCCAGTCAC GGAGACACAG AGCACATGGT GTATTTTGCA 
GTGATCATGC AGGACTATGA ACGGGTGGTC GCATACCACT GCCAGCATGA GGCTTACGAG 
GAGGCCCTGG CTGTGCTTGC CCGCCACCGG GACCCCCAGC TCTTCTACAA ATTCTCCCCC 
ATTCTCATCC GCCACATCCC CCGCCAGCTC GTAGACGCCT GGATTGAGAT GGGCAGCCGG 
CTGGATGCTC GGCAGCTCAT CCCTGCCCTG GTGAACTACA GCCAGGGCGG TGAGGCCCAG 
CAGGTGAGCC AGGCCATCCG CTACATGGAA TTCTGCGTGA ATGTGCTCGG TGAGACGGAG 
CAGGCCATTC ACAACTACCT GCTGTCCCTG TATGCCCGTG GCCAGCCAGC CTCACTTCTG 
GCATACCTGG AACAAGCTGG GGCCAGCCCG CACCGTGTAC ATTATGATCT CAAATATGCA 
CTTCGACTTT GTGCTGAGCA CGGCCACCAC CGCGCCTGCG TCCATGTCTA TAAGGTGTTG 
GAGCTATATG AGGAGGCTGT GGACCTGGCC CTGCAGGTGG ATGTGGACCT GGCCAAGCAG 
TGTGCAGACT TGCCGGAGGA GGATGAGGAA CTTCGCAAGA AACTATGGCT CAAGATCGCC 
CGGCACGTGG TGCAGGAGGA AGAAGACGTC CAGACAGCCA TGGCCTGCTT GGCCAGCTGC 
CCCTTGCTCA AGATCGAGGA TGTGCTGCCC TTCTTCCCTG ACTTTGTCAC CATCGACCAC 
TTCAAGGAGG CAATCTGTAG TTCCCTGAAG GCCTACAACC ACCACATCCA GGAGCTGCAG 
CGCGAGATGG AAGAAGCCAC AGCCAGTGCC CAGCGCATCC GACGAGACTT GCAGGAGCTC 
CGAGGCCGCT ATGGCACCGT GGAGCCCCAG GACAAATGCT CCACCTGTGA CTTTCCTTTG 
CTCAACCGAC CCTTTTACCT GTTTCTCTGT GGCCACATGT TTCACGCTGA CTGTCTCCTA 
CAGGCTGTGC GGCCCGGCCT CCCTGCCTAC AAGCAGGCCA GACTTGAGGA ACTGCAGCGC 
AAGCTTGGGG CGGCGCCTCC TCCGACCAAA GGCTCCGTGA AGGCCAAGGA GGCAGAAGCT 
GGGGCTGCAG CGGTGGGGCC CAGTCGGGAG CAGCTCAAGG CTGACCTGGA TGAGCTGGTG 
GCTGCTGAGT GTGTGTACTG TGGGGAGCTG ATGATTCGGT CTATCGACCG GCCCTTCATT 
GATCCGCAGC GCTATGAGGA GGAGCACCTC AGCTGGCTAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.
Nature neuroscience18(6)826-35(2015 Jun)
Laguna A,Schintu N,Nobre A,Alvarsson A,Volakakis N,Jacobsen JK,G?mez-Gal?n M,Sopova E,Joodmardi E,Yoshitake T,Deng Q,Kehr J,Ericson J,Svenningsson P,Shupliakov O,Perlmann T

Mammalian CORVET is required for fusion and conversion of distinct early endosome subpopulations.
Traffic (Copenhagen, Denmark)15(12)1366-89(2014 Dec)
Perini ED,Schaefer R,St?ter M,Kalaidzidis Y,Zerial M

UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs.
Proceedings of the National Academy of Sciences of the United States of America111(7)2716-21(2014 Feb)
Pirooz SD,He S,Zhang T,Zhang X,Zhao Z,Oh S,O'Connell D,Khalilzadeh P,Amini-Bavil-Olyaee S,Farzan M,Liang C

Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes.
The Journal of biological chemistry287(39)32861-73(2012 Sep)
Peng C,Ye J,Yan S,Kong S,Shen Y,Li C,Li Q,Zheng Y,Deng K,Xu T,Tao W

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Vps18 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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