Zfy1 cDNA ORF clone, Mus musculus(house mouse)

RNAi as a tool to control the sex ratio of mouse offspring by interrupting Zfx/Zfy genes in the testis.
Zhang Y, Xi J, Jia B, Wang X, Wang X, Li C, Li Y, Zeng X, Ying R, Li X, Jiang S, Yuan F
Mammalian genome : official journal of the International Mammalian Genome Society28(3-4)100-105(2017 Apr)

Complementary Critical Functions of Zfy1 and Zfy2 in Mouse Spermatogenesis and Reproduction.
Nakasuji T, Ogonuki N, Chiba T, Kato T, Shiozawa K, Yamatoya K, Tanaka H, Kondo T, Miyado K, Miyasaka N, Kubota T, Ogura A, Asahara H
PLoS genetics13(1)e1006578(2017 Jan)

Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes.
Vernet N, Mahadevaiah SK, de Rooij DG, Burgoyne PS, Ellis PJI
Human molecular genetics25(24)5300-5310(2016 12)

Lgr4 controls specialization of female gonads in mice.
Koizumi M, Oyama K, Yamakami Y, Kida T, Satoh R, Kato S, Hidema S, Oe T, Goto T, Clevers H, Nawa A, Nishimori K
Biology of reproduction93(4)90(2015 Oct)

Mouse Y-linked Zfy1 and Zfy2 are expressed during the male-specific interphase between meiosis I and meiosis II and promote the 2nd meiotic division.
Vernet N, Mahadevaiah SK, Yamauchi Y, Decarpentrie F, Mitchell MJ, Ward MA, Burgoyne PS
PLoS genetics10(6)e1004444(2014 Jun)

our findings show that RNAi-mediated disruption of Zfx/Zfy in mouse testis affected X/Y spermatogenesis. Additionally, results suggest that the paralogous genes Zfx/Zfy play an important role in the process of X and Y sperm development. The individual interference of Zfx/Zfy may predict the outcome of X and Y haploid sperms. Presented herein is an advanced method developed to control mouse X/Y spermatogenesis and sex rati
Title: RNAi as a tool to control the sex ratio of mouse offspring by interrupting Zfx/Zfy genes in the testis.

Zfy1-KO mice did not show any significant phenotypic alterations. Zfy1/2-DKO mice were infertile and displayed abnormal sperm morphology and fertilization failure.
Title: Complementary Critical Functions of Zfy1 and Zfy2 in Mouse Spermatogenesis and Reproduction.

we show that in mice, Zfy genes(Zfy1 and Zfy2 ) are also necessary for efficient meiotic sex chrand the sex chromosomes are not correctly silenced in Zfy-deficient spermatocytes.
Title: Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes.

genetic information on the short arm of the Y chromosome promotes meiosis II, and by transgene addition Zfy1 and Zfy2 were identified as the genes responsible.
Title: Mouse Y-linked Zfy1 and Zfy2 are expressed during the male-specific interphase between meiosis I and meiosis II and promote the 2nd meiotic division.

Studies identified a Zfy2 transcript that predominates in spermatids, and a Zfy1 transcript, lacking an exon encoding approximately half of the acidic domain.
Title: Human and mouse ZFY genes produce a conserved testis-specific transcript encoding a zinc finger protein with a short acidic domain and modified transactivation potential.