Lamc1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lamc1
Entrez Gene ID	226519
Full Name	laminin, gamma 1
Synonyms	Lamb2
General protein information	Preferred Names laminin, gamma 1 Names laminin subunit gamma-1 S-LAM gamma S-laminin subunit gamma laminin B2 chain laminin-1 subunit gamma laminin-10 subunit gamma laminin-11 subunit gamma laminin-2 subunit gamma laminin-3 subunit gamma laminin-4 subunit gamma laminin-6 subunit gamma laminin-7 subunit gamma laminin-8 subunit gamma laminin-9 subunit gamma
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 G3\|1 65.3 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010683.2	NP_034813.2	laminin subunit gamma-1 precursor

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	lamc1	NP_775384.1
Xenopus tropicalis (tropical clawed frog)	lamc1	NP_001090659.1
Homo sapiens (human)	LAMC1	NP_002284.3
Canis lupus familiaris (dog)	LAMC1	XP_537156.3
Rattus norvegicus (Norway rat)	Lamc1	NP_446418.1
Anopheles gambiae (African malaria mosquito)	LANB2	XP_308240.3
Pan troglodytes (chimpanzee)	LAMC1	XP_001162648.1
Bos taurus (cattle)	LAMC1	NP_001193746.1
Caenorhabditis elegans (roundworm)	lam-2	NP_509204.3
	LOC715265	XP_002808304.1
Mus musculus (house mouse)	Lamc1	NP_034813.2
Gallus gallus (chicken)	LAMC1	XP_001234659.2
Drosophila melanogaster (fruit fly)	LanB2	NP_524006.1

Gene Ontology
Bibliography

Related articles in PubMed

Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination.
Ghidinelli M, Poitelon Y, Shin YK, Ameroso D, Williamson C, Ferri C, Pellegatta M, Espino K, Mogha A, Monk K, Podini P, Taveggia C, Nave KA, Wrabetz L, Park HT, Feltri ML
PLoS biology15(6)e2001408(2017 Jun)

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Naba A, Clauser KR, Mani DR, Carr SA, Hynes RO
Scientific reports740495(2017 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that laminin alpha2beta1gamma1 (Lm211) can inhibit neuregulin 1 type III (Nrg1III) by limiting protein kinase A (PKA) activation, which is required to initiate myelination.
Title: Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination.

Embryo implantation triggers dynamic spatiotemporal expression of the basement membrane toolkit (Col4a1, GPBP, Lamc1, peroxidasin) during uterine reprogramming.
Title: Embryo implantation triggers dynamic spatiotemporal expression of the basement membrane toolkit during uterine reprogramming.

These findings document a pathogenic potential of antibodies targeting the laminin gamma1 N-terminus.
Title: Ex vivo pathogenicity of anti-laminin ?1 autoantibodies.

Analysis of nidogen-1 and laminin-gamma1 interaction reveals multiple binding modes.
Title: Analysis of nidogen-1/laminin ?1 interaction by cross-linking, mass spectrometry, and computational modeling reveals multiple binding modes.

The C-terminal domains of mouse laminin gamma 1 and nidogen 1 mediate interactions complex formation.
Title: Structural elucidation of full-length nidogen and the laminin-nidogen complex in solution.

The following Lamc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lamc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu06613	NM_010683.2 Latest version!	Mus musculus laminin, gamma 1 (Lamc1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$811.30 $1159.00

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lamc1 ( NM_010683.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034813.2 Mus musculus laminin, gamma 1 (Lamc1), mRNA.

Price & Availability↑

CloneID	OMu06613
Clone ID Related Accession (Same CDS sequence)	NM_010683.2
Accession Version	NM_010683.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4824bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-26
Organism	Mus musculus(house mouse)
Product	laminin subunit gamma-1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC117550.8 and AC159966.5. On Jul 25, 2007 this sequence version replaced NM_010683.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J03484.1, J02930.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGACGGGCG GCGGGCGGGC CGCGCTGGCC CTGCAGCCCC GGGGGCGGCT GTGGCCGCTG 
TTGGCTGTGC TGGCGGCTGT GGCGGGCTGT GTCCGGGCGG CCATGGACGA GTGCGCGGAT 
GAGGGCGGGC GGCCGCAGCG CTGCATGCCG GAGTTTGTTA ATGCCGCCTT CAATGTGACC 
GTGGTGGCTA CCAACACGTG TGGGACTCCG CCCGAGGAGT ACTGCGTGCA GACTGGGGTG 
ACCGGAGTCA CTAAGTCCTG TCACCTGTGC GACGCCGGCC AGCAGCACCT GCAACACGGG 
GCAGCCTTCC TGACCGACTA CAACAACCAG GCCGACACCA CCTGGTGGCA AAGCCAGACT 
ATGCTGGCCG GGGTGCAGTA CCCCAACTCC ATCAACCTCA CGCTGCACCT GGGAAAGGCT 
TTTGACATCA CTTACGTGCG CCTCAAGTTC CACACCAGCC GTCCAGAGAG CTTCGCCATC 
TATAAGCGCA CTCGGGAAGA CGGGCCCTGG ATTCCTTATC AGTACTACAG TGGGTCCTGT 
GAGAACACGT ACTCAAAGGC TAACCGTGGC TTCATCAGGA CCGGAGGGGA CGAGCAGCAG 
GCCTTGTGTA CTGATGAATT CAGTGACATT TCCCCCCTCA CCGGTGGCAA CGTGGCCTTT 
TCAACCCTGG AAGGACGGCC GAGTGCCTAC AACTTTGACA ACAGCCCTGT GCTCCAGGAA 
TGGGTAACTG CCACTGACAT CAGAGTGACG CTCAATCGCC TGAACACCTT TGGAGATGAA 
GTGTTTAACG ACCCCAAAGT TCTCAAGTCT TACTATTACG CAATCTCAGA CTTTGCTGTG 
GGCGGCAGGT GTAAATGTAA CGGACATGCC AGCGAGTGTG TAAAGAACGA GTTTGACAAA 
CTCATGTGCA ACTGCAAACA TAACACATAC GGAGTTGACT GTGAAAAGTG CCTGCCTTTC 
TTCAATGACC GGCCGTGGAG GAGGGCGACT GCTGAGAGCG CCAGCGAGTG CCTTCCTTGT 
GACTGCAATG GCCGATCCCA AGAGTGCTAC TTTGATCCTG AACTATACCG TTCCACTGGA 
CATGGTGGCC ACTGTACCAA CTGCCGGGAT AACACAGATG GTGCCAAGTG CGAGAGGTGC 
CGGGAGAATT TCTTCCGCCT GGGGAACACT GAAGCCTGCT CTCCGTGCCA CTGCAGCCCT 
GTTGGTTCTC TCAGCACACA GTGTGACAGT TACGGCAGAT GCAGCTGTAA GCCAGGAGTG 
ATGGGTGACA AGTGTGACCG TTGTCAGCCT GGGTTCCATT CCCTCACTGA GGCAGGATGC 
AGGCCATGCT CCTGCGATCC TTCGGGCAGC ACAGACGAGT GTAATGTTGA AACAGGAAGA 
TGCGTTTGCA AAGACAATGT TGAAGGCTTC AACTGTGAGA GATGCAAACC TGGATTTTTT 
AATCTGGAGT CATCTAATCC TAAGGGCTGC ACACCCTGCT TCTGCTTTGG CCATTCTTCT 
GTGTGCACAA ATGCTGTTGG CTACAGTGTT TATGACATCT CCTCCACCTT TCAGATTGAT 
GAGGATGGGT GGCGCGTGGA GCAGAGAGAT GGCTCGGAGG CGTCTCTGGA GTGGTCCTCA 
GACAGGCAAG ATATTGCCGT AATCTCAGAC AGTTACTTTC CTAGATACTT CATCGCCCCT 
GTGAAGTTCC TGGGCAACCA GGTCCTGAGT TATGGGCAGA ATCTTTCCTT CTCCTTCCGA 
GTGGACAGAC GAGACACTCG CCTCTCCGCA GAGGACCTTG TGCTCGAAGG AGCTGGCTTG 
AGAGTATCCG TGCCCTTGAT CGCTCAGGGC AACTCCTACC CCAGCGAGAC CACTGTGAAG 
TACATCTTCA GGCTCCATGA AGCAACGGAT TACCCTTGGA GGCCCGCTCT CTCCCCGTTT 
GAATTTCAGA AGCTCCTGAA CAACTTGACC TCTATCAAGA TCCGTGGTAC ATACAGCGAG 
AGGAGCGCTG GGTACTTGGA TGATGTCACC TTGCAAAGTG CTCGCCCTGG GCCCGGAGTC 
CCTGCAACGT GGGTGGAGTC CTGCACCTGT CCAGTGGGAT ACGGGGGACA GTTCTGTGAG 
ACGTGCCTCC CAGGGTACAG AAGAGAAACT CCAAGCCTTG GACCTTATAG CCCGTGTGTG 
CTCTGTACCT GTAATGGGCA CAGTGAGACC TGTGACCCGG AGACAGGTGT CTGTGACTGC 
AGAGACAATA CAGCCGGCCC CCACTGTGAG AAATGTAGCG ATGGGTACTA TGGGGACTCA 
ACCCTGGGCA CCTCCTCTGA CTGCCAGCCT TGTCCCTGCC CCGGTGGCTC AAGTTGTGCC 
ATTGTCCCAA AGACAAAGGA AGTGGTGTGC ACGCACTGTC CGACTGGCAC TGCCGGCAAG 
AGATGTGAAC TCTGTGATGA CGGCTACTTT GGAGACCCTC TGGGCAGCAA TGGGCCTGTG 
AGACTGTGCC GCCCGTGCCA GTGTAACGAC AACATAGACC CCAACGCGGT TGGCAACTGC 
AACCGCCTGA CGGGCGAGTG CCTGAAGTGC ATCTATAACA CGGCTGGTTT CTACTGCGAC 
CGGTGCAAGG AAGGGTTTTT CGGAAATCCC CTGGCTCCCA ATCCAGCCGA CAAATGCAAA 
GCCTGCGCCT GCAATCCCTA CGGGACAGTG CAGCAACAGA GCAGCTGTAA CCCGGTGACC 
GGACAGTGCC AGTGTCTGCC TCATGTGTCT GGCCGCGACT GCGGTACTTG TGACCCTGGC 
TACTACAACC TGCAGAGCGG GCAAGGCTGC GAGAGGTGTG ACTGCCATGC TTTGGGTTCC 
ACCAATGGGC AGTGTGACAT CCGCACCGGG CAGTGTGAGT GCCAGCCTGG CATCACCGGC 
CAGCACTGTG AGCGCTGTGA GACCAACCAC TTTGGGTTTG GACCTGAAGG CTGCAAACCT 
TGTGACTGTC ACCATGAAGG ATCCCTTTCA CTCCAGTGTA AAGAGGACGG CCGTTGTGAA 
TGCAGGGAAG GCTTTGTGGG CAATCGCTGT GACCAGTGTG AAGAGAACTA TTTCTACAAT 
CGGTCCTGGC CTGGCTGCCA GGAGTGTCCG GCTTGTTACC GACTGGTGAA GGATAAGGTT 
GCTGAGCATC GAGTGAAACT CCAGGAGTTA GAGAGCCTCA TCGCCAACCT TGGCACTGGG 
GATGACATGG TGACAGATCA AGCCTTTGAG GACAGACTTA AGGAAGCAGA AAGGGAGGTG 
ACAGACCTTC TCCGTGAGGC TCAGGAAGTC AAAGATGTAG ATCAAAATCT GATGGATCGC 
CTTCAGAGAG TAAATAGCAG CCTGCATAGC CAAATTAGCC GACTGCAGAA TATCCGGAAT 
ACTATCGAAG AGACCGGGAT CTTGGCTGAG CGAGCACGGT CCCGAGTGGA GAGTACAGAG 
CAGCTGATTG AGATCGCCTC CAGGGAGCTC GAGAAAGCAA AAATGGCTGC CGCCAATGTG 
TCAATCACTC AGCCAGAGTC TACAGGGGAG CCAAACAACA TGACCCTCTT GGCAGAAGAA 
GCCCGAAAGC TTGCAGAGCG TCATAAACAG GAAGCCGATG ACATTGTACG AGTGGCAAAG 
ACAGCCAACG AGACTTCAGC TGAGGCATAT AATCTGCTTT TGAGGACCCT GGCAGGAGAA 
AATCAAACTG CGCTGGAGAT TGAAGAACTT AACCGGAAGT ATGAACAAGC AAAGAACATC 
TCTCAGGACC TGGAGAAGCA GGCTGCCCGA GTCCATGAGG AAGCCAAGCG TGCAGGTGAC 
AAAGCCGTAG AGATCTATGC CAGTGTGGCC CAGCTGACCC CTGTGGACTC TGAGGCCCTG 
GAGAATGAAG CAAATAAAAT CAAGAAAGAA GCTGCAGACC TGGACCGTCT GATTGACCAG 
AAGCTAAAGG ATTACGAGGA CCTCAGGGAA GACATGAGAG GAAAGGAACA TGAAGTGAAG 
AACCTTCTAG AGAAGGGGAA AGCTGAACAG CAGACCGCCG ACCAACTCCT AGCTCGAGCC 
GATGCTGCCA AGGCCCTTGC TGAAGAAGCT GCTAAGAAGG GACGCAGTAC CTTACAAGAA 
GCCAATGACA TTCTCAACAA CCTGAAAGAT TTTGATAGAC GCGTGAACGA TAACAAGACA 
GCCGCGGAAG AAGCTCTAAG GAGAATTCCC GCCATCAACC GGACCATAGC TGAAGCCAAT 
GAGAAGACAA GGGAGGCCCA GCTAGCGCTG GGCAATGCTG CCGCTGACGC CACGGAGGCC 
AAGAACAAGG CCCATGAGGC AGAGAGGATT GCCAGCGCCG TGCAGAAGAA TGCCACCAGT 
ACCAAGGCGG ACGCAGAAAG AACCTTCGGG GAAGTTACAG ATCTGGATAA TGAGGTGAAT 
GGTATGCTGA GGCAGCTGGA GGAGGCAGAG AATGAGCTGA AGAAGAAGCA AGATGATGCC 
GACCAGGACA TGATGATGGC AGGGATGGCT TCGCAGGCTG CTCAGGAGGC TGAGCTCAAT 
GCCAGAAAGG CCAAAAACTC TGTCAGCAGC CTCCTCAGCC AGCTGAACAA CCTCTTGGAT 
CAGCTAGGAC AGCTGGACAC AGTGGACCTG AACAAGCTCA ATGAGATCGA AGGCTCCCTG 
AACAAAGCCA AAGACGAAAT GAAGGCCAGC GACCTGGACA GGAAGGTGTC TGACCTGGAG 
AGCGAGGCTC GGAAGCAGGA GGCAGCCATC ATGGACTATA ACCGGGACAT AGCAGAGATC 
ATTAAGGATA TTCACAACCT GGAGGACATC AAGAAGACCC TACCAACCGG CTGCTTCAAC 
ACCCCGTCCA TCGAGAAGCC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034813.2
CDS	248..5071
Translation	MTGGGRAALALQPRGRLWPLLAVLAAVAGCVRAAMDECADEGGRPQRCMPEFVNAAFNVTVVATNTCGTPPEEYCVQTGVTGVTKSCHLCDAGQQHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPNSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECVKNEFDKLMCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCRDNTDGAKCERCRENFFRLGNTEACSPCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSTDECNVETGRCVCKDNVEGFNCERCKPGFFNLESSNPKGCTPCFCFGHSSVCTNAVGYSVYDISSTFQIDEDGWRVEQRDGSEASLEWSSDRQDIAVISDSYFPRYFIAPVKFLGNQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSETTVKYIFRLHEATDYPWRPALSPFEFQKLLNNLTSIKIRGTYSERSAGYLDDVTLQSARPGPGVPATWVESCTCPVGYGGQFCETCLPGYRRETPSLGPYSPCVLCTCNGHSETCDPETGVCDCRDNTAGPHCEKCSDGYYGDSTLGTSSDCQPCPCPGGSSCAIVPKTKEVVCTHCPTGTAGKRCELCDDGYFGDPLGSNGPVRLCRPCQCNDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKEGFFGNPLAPNPADKCKACACNPYGTVQQQSSCNPVTGQCQCLPHVSGRDCGTCDPGYYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCETNHFGFGPEGCKPCDCHHEGSLSLQCKEDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVAEHRVKLQELESLIANLGTGDDMVTDQAFEDRLKEAEREVTDLLREAQEVKDVDQNLMDRLQRVNSSLHSQISRLQNIRNTIEETGILAERARSRVESTEQLIEIASRELEKAKMAAANVSITQPESTGEPNNMTLLAEEARKLAERHKQEADDIVRVAKTANETSAEAYNLLLRTLAGENQTALEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLTPVDSEALENEANKIKKEAADLDRLIDQKLKDYEDLREDMRGKEHEVKNLLEKGKAEQQTADQLLARADAAKALAEEAAKKGRSTLQEANDILNNLKDFDRRVNDNKTAAEEALRRIPAINRTIAEANEKTREAQLALGNAAADATEAKNKAHEAERIASAVQKNATSTKADAERTFGEVTDLDNEVNGMLRQLEEAENELKKKQDDADQDMMMAGMASQAAQEAELNARKAKNSVSSLLSQLNNLLDQLGQLDTVDLNKLNEIEGSLNKAKDEMKASDLDRKVSDLESEARKQEAAIMDYNRDIAEIIKDIHNLEDIKKTLPTGCFNTPSIEKP

Target ORF information:

RefSeq Version	NM_010683.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus laminin, gamma 1 (Lamc1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010683.2

ORF Insert Sequence:

ATGACGGGCG GCGGGCGGGC CGCGCTGGCC CTGCAGCCCC GGGGGCGGCT GTGGCCGCTG 
TTGGCTGTGC TGGCGGCTGT GGCGGGCTGT GTCCGGGCGG CCATGGACGA GTGCGCGGAT 
GAGGGCGGGC GGCCGCAGCG CTGCATGCCG GAGTTTGTTA ATGCCGCCTT CAATGTGACC 
GTGGTGGCTA CCAACACGTG TGGGACTCCG CCCGAGGAGT ACTGCGTGCA GACTGGGGTG 
ACCGGAGTCA CTAAGTCCTG TCACCTGTGC GACGCCGGCC AGCAGCACCT GCAACACGGG 
GCAGCCTTCC TGACCGACTA CAACAACCAG GCCGACACCA CCTGGTGGCA AAGCCAGACT 
ATGCTGGCCG GGGTGCAGTA CCCCAACTCC ATCAACCTCA CGCTGCACCT GGGAAAGGCT 
TTTGACATCA CTTACGTGCG CCTCAAGTTC CACACCAGCC GTCCAGAGAG CTTCGCCATC 
TATAAGCGCA CTCGGGAAGA CGGGCCCTGG ATTCCTTATC AGTACTACAG TGGGTCCTGT 
GAGAACACGT ACTCAAAGGC TAACCGTGGC TTCATCAGGA CCGGAGGGGA CGAGCAGCAG 
GCCTTGTGTA CTGATGAATT CAGTGACATT TCCCCCCTCA CCGGTGGCAA CGTGGCCTTT 
TCAACCCTGG AAGGACGGCC GAGTGCCTAC AACTTTGACA ACAGCCCTGT GCTCCAGGAA 
TGGGTAACTG CCACTGACAT CAGAGTGACG CTCAATCGCC TGAACACCTT TGGAGATGAA 
GTGTTTAACG ACCCCAAAGT TCTCAAGTCT TACTATTACG CAATCTCAGA CTTTGCTGTG 
GGCGGCAGGT GTAAATGTAA CGGACATGCC AGCGAGTGTG TAAAGAACGA GTTTGACAAA 
CTCATGTGCA ACTGCAAACA TAACACATAC GGAGTTGACT GTGAAAAGTG CCTGCCTTTC 
TTCAATGACC GGCCGTGGAG GAGGGCGACT GCTGAGAGCG CCAGCGAGTG CCTTCCTTGT 
GACTGCAATG GCCGATCCCA AGAGTGCTAC TTTGATCCTG AACTATACCG TTCCACTGGA 
CATGGTGGCC ACTGTACCAA CTGCCGGGAT AACACAGATG GTGCCAAGTG CGAGAGGTGC 
CGGGAGAATT TCTTCCGCCT GGGGAACACT GAAGCCTGCT CTCCGTGCCA CTGCAGCCCT 
GTTGGTTCTC TCAGCACACA GTGTGACAGT TACGGCAGAT GCAGCTGTAA GCCAGGAGTG 
ATGGGTGACA AGTGTGACCG TTGTCAGCCT GGGTTCCATT CCCTCACTGA GGCAGGATGC 
AGGCCATGCT CCTGCGATCC TTCGGGCAGC ACAGACGAGT GTAATGTTGA AACAGGAAGA 
TGCGTTTGCA AAGACAATGT TGAAGGCTTC AACTGTGAGA GATGCAAACC TGGATTTTTT 
AATCTGGAGT CATCTAATCC TAAGGGCTGC ACACCCTGCT TCTGCTTTGG CCATTCTTCT 
GTGTGCACAA ATGCTGTTGG CTACAGTGTT TATGACATCT CCTCCACCTT TCAGATTGAT 
GAGGATGGGT GGCGCGTGGA GCAGAGAGAT GGCTCGGAGG CGTCTCTGGA GTGGTCCTCA 
GACAGGCAAG ATATTGCCGT AATCTCAGAC AGTTACTTTC CTAGATACTT CATCGCCCCT 
GTGAAGTTCC TGGGCAACCA GGTCCTGAGT TATGGGCAGA ATCTTTCCTT CTCCTTCCGA 
GTGGACAGAC GAGACACTCG CCTCTCCGCA GAGGACCTTG TGCTCGAAGG AGCTGGCTTG 
AGAGTATCCG TGCCCTTGAT CGCTCAGGGC AACTCCTACC CCAGCGAGAC CACTGTGAAG 
TACATCTTCA GGCTCCATGA AGCAACGGAT TACCCTTGGA GGCCCGCTCT CTCCCCGTTT 
GAATTTCAGA AGCTCCTGAA CAACTTGACC TCTATCAAGA TCCGTGGTAC ATACAGCGAG 
AGGAGCGCTG GGTACTTGGA TGATGTCACC TTGCAAAGTG CTCGCCCTGG GCCCGGAGTC 
CCTGCAACGT GGGTGGAGTC CTGCACCTGT CCAGTGGGAT ACGGGGGACA GTTCTGTGAG 
ACGTGCCTCC CAGGGTACAG AAGAGAAACT CCAAGCCTTG GACCTTATAG CCCGTGTGTG 
CTCTGTACCT GTAATGGGCA CAGTGAGACC TGTGACCCGG AGACAGGTGT CTGTGACTGC 
AGAGACAATA CAGCCGGCCC CCACTGTGAG AAATGTAGCG ATGGGTACTA TGGGGACTCA 
ACCCTGGGCA CCTCCTCTGA CTGCCAGCCT TGTCCCTGCC CCGGTGGCTC AAGTTGTGCC 
ATTGTCCCAA AGACAAAGGA AGTGGTGTGC ACGCACTGTC CGACTGGCAC TGCCGGCAAG 
AGATGTGAAC TCTGTGATGA CGGCTACTTT GGAGACCCTC TGGGCAGCAA TGGGCCTGTG 
AGACTGTGCC GCCCGTGCCA GTGTAACGAC AACATAGACC CCAACGCGGT TGGCAACTGC 
AACCGCCTGA CGGGCGAGTG CCTGAAGTGC ATCTATAACA CGGCTGGTTT CTACTGCGAC 
CGGTGCAAGG AAGGGTTTTT CGGAAATCCC CTGGCTCCCA ATCCAGCCGA CAAATGCAAA 
GCCTGCGCCT GCAATCCCTA CGGGACAGTG CAGCAACAGA GCAGCTGTAA CCCGGTGACC 
GGACAGTGCC AGTGTCTGCC TCATGTGTCT GGCCGCGACT GCGGTACTTG TGACCCTGGC 
TACTACAACC TGCAGAGCGG GCAAGGCTGC GAGAGGTGTG ACTGCCATGC TTTGGGTTCC 
ACCAATGGGC AGTGTGACAT CCGCACCGGG CAGTGTGAGT GCCAGCCTGG CATCACCGGC 
CAGCACTGTG AGCGCTGTGA GACCAACCAC TTTGGGTTTG GACCTGAAGG CTGCAAACCT 
TGTGACTGTC ACCATGAAGG ATCCCTTTCA CTCCAGTGTA AAGAGGACGG CCGTTGTGAA 
TGCAGGGAAG GCTTTGTGGG CAATCGCTGT GACCAGTGTG AAGAGAACTA TTTCTACAAT 
CGGTCCTGGC CTGGCTGCCA GGAGTGTCCG GCTTGTTACC GACTGGTGAA GGATAAGGTT 
GCTGAGCATC GAGTGAAACT CCAGGAGTTA GAGAGCCTCA TCGCCAACCT TGGCACTGGG 
GATGACATGG TGACAGATCA AGCCTTTGAG GACAGACTTA AGGAAGCAGA AAGGGAGGTG 
ACAGACCTTC TCCGTGAGGC TCAGGAAGTC AAAGATGTAG ATCAAAATCT GATGGATCGC 
CTTCAGAGAG TAAATAGCAG CCTGCATAGC CAAATTAGCC GACTGCAGAA TATCCGGAAT 
ACTATCGAAG AGACCGGGAT CTTGGCTGAG CGAGCACGGT CCCGAGTGGA GAGTACAGAG 
CAGCTGATTG AGATCGCCTC CAGGGAGCTC GAGAAAGCAA AAATGGCTGC CGCCAATGTG 
TCAATCACTC AGCCAGAGTC TACAGGGGAG CCAAACAACA TGACCCTCTT GGCAGAAGAA 
GCCCGAAAGC TTGCAGAGCG TCATAAACAG GAAGCCGATG ACATTGTACG AGTGGCAAAG 
ACAGCCAACG AGACTTCAGC TGAGGCATAT AATCTGCTTT TGAGGACCCT GGCAGGAGAA 
AATCAAACTG CGCTGGAGAT TGAAGAACTT AACCGGAAGT ATGAACAAGC AAAGAACATC 
TCTCAGGACC TGGAGAAGCA GGCTGCCCGA GTCCATGAGG AAGCCAAGCG TGCAGGTGAC 
AAAGCCGTAG AGATCTATGC CAGTGTGGCC CAGCTGACCC CTGTGGACTC TGAGGCCCTG 
GAGAATGAAG CAAATAAAAT CAAGAAAGAA GCTGCAGACC TGGACCGTCT GATTGACCAG 
AAGCTAAAGG ATTACGAGGA CCTCAGGGAA GACATGAGAG GAAAGGAACA TGAAGTGAAG 
AACCTTCTAG AGAAGGGGAA AGCTGAACAG CAGACCGCCG ACCAACTCCT AGCTCGAGCC 
GATGCTGCCA AGGCCCTTGC TGAAGAAGCT GCTAAGAAGG GACGCAGTAC CTTACAAGAA 
GCCAATGACA TTCTCAACAA CCTGAAAGAT TTTGATAGAC GCGTGAACGA TAACAAGACA 
GCCGCGGAAG AAGCTCTAAG GAGAATTCCC GCCATCAACC GGACCATAGC TGAAGCCAAT 
GAGAAGACAA GGGAGGCCCA GCTAGCGCTG GGCAATGCTG CCGCTGACGC CACGGAGGCC 
AAGAACAAGG CCCATGAGGC AGAGAGGATT GCCAGCGCCG TGCAGAAGAA TGCCACCAGT 
ACCAAGGCGG ACGCAGAAAG AACCTTCGGG GAAGTTACAG ATCTGGATAA TGAGGTGAAT 
GGTATGCTGA GGCAGCTGGA GGAGGCAGAG AATGAGCTGA AGAAGAAGCA AGATGATGCC 
GACCAGGACA TGATGATGGC AGGGATGGCT TCGCAGGCTG CTCAGGAGGC TGAGCTCAAT 
GCCAGAAAGG CCAAAAACTC TGTCAGCAGC CTCCTCAGCC AGCTGAACAA CCTCTTGGAT 
CAGCTAGGAC AGCTGGACAC AGTGGACCTG AACAAGCTCA ATGAGATCGA AGGCTCCCTG 
AACAAAGCCA AAGACGAAAT GAAGGCCAGC GACCTGGACA GGAAGGTGTC TGACCTGGAG 
AGCGAGGCTC GGAAGCAGGA GGCAGCCATC ATGGACTATA ACCGGGACAT AGCAGAGATC 
ATTAAGGATA TTCACAACCT GGAGGACATC AAGAAGACCC TACCAACCGG CTGCTTCAAC 
ACCCCGTCCA TCGAGAAGCC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination.
PLoS biology15(6)e2001408(2017 Jun)
Ghidinelli M,Poitelon Y,Shin YK,Ameroso D,Williamson C,Ferri C,Pellegatta M,Espino K,Mogha A,Monk K,Podini P,Taveggia C,Nave KA,Wrabetz L,Park HT,Feltri ML

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Scientific reports740495(2017 Jan)
Naba A,Clauser KR,Mani DR,Carr SA,Hynes RO

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Lamc1 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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