Ywhaz cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ywhaz
Entrez Gene ID	22631
Full Name	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
Synonyms	1110013I11Rik,14-3-3zeta,AI596267,AL022924,AU020854
General protein information	Preferred Names tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide Names 14-3-3 protein zeta/delta 14-3-3 zeta KCIP-1 SEZ-2 protein kinase C inhibitor protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15\|15 B3.1

mRNA and Protein(s)

mRNA	Protein	Name
XM_030248527.1	XP_030104387.1	14-3-3 protein zeta/delta isoform X1
NM_001356569.1	NP_001343498.1	14-3-3 protein zeta/delta isoform 1
NM_001253807.1	NP_001240736.1	14-3-3 protein zeta/delta isoform 2
NM_001253805.1	NP_001240734.1	14-3-3 protein zeta/delta isoform 1
XM_011245352.1	XP_011243654.1	14-3-3 protein zeta/delta isoform X1
NM_001253806.1	NP_001240735.1	14-3-3 protein zeta/delta isoform 1
XM_011245352.2	XP_011243654.1	14-3-3 protein zeta/delta isoform X1
NM_011740.3	NP_035870.1	14-3-3 protein zeta/delta isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	YWHAZ	NP_001129173.1
Canis lupus familiaris (dog)	YWHAZ	XP_849044.1
Pan troglodytes (chimpanzee)	YWHAZ	XP_003951364.1
	YWHAZ	XP_002805465.1
Mus musculus (house mouse)	Ywhaz	NP_001240734.1
Rattus norvegicus (Norway rat)	Ywhaz	NP_037143.2
Gallus gallus (chicken)	YWHAZ	NP_001026514.1
Danio rerio (zebrafish)	ywhabl	NP_955856.1
Caenorhabditis elegans (roundworm)	par-5	NP_502235.1
Bos taurus (cattle)	YWHAZ	NP_777239.1
Drosophila melanogaster (fruit fly)	14-3-3zeta	NP_995792.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007643	XP_001687869.1
Caenorhabditis elegans (roundworm)	ftt-2	NP_509939.1
Xenopus tropicalis (tropical clawed frog)	ywhaz	NP_989173.1

Gene Ontology
Bibliography

Related articles in PubMed

MicroRNA-146a promotes IgE class switch in B cells via upregulating 14-3-3? expression.
Li F, Huang Y, Huang YY, Kuang YS, Wei YJ, Xiang L, Zhang XJ, Jia ZC, Jiang S, Li JY, Wan Y
Molecular immunology92180-189(2017 Dec)

14-3-3? loss impedes oncogene-induced mammary tumorigenesis and metastasis by attenuating oncogenic signaling.
Joshi S, Yang J, Wang Q, Li P, Wang H, Zhang Q, Xiong Y, Pickering BF, Parker-Thornburg J, Behringer RR, Yu D
American journal of cancer research7(8)1654-1664(2017)

14-3-3? loss leads to neonatal lethality by microRNA-126 downregulation-mediated developmental defects in lung vasculature.
Yang J, Joshi S, Wang Q, Li P, Wang H, Xiong Y, Xiao Y, Wang J, Parker-Thornburg J, Behringer RR, Yu D
Cell & bioscience758(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results demonstrate that miR-146a enhances class switch and secretion of IgE in B cells by upregulating 14-3-3sigma expression, and suggest that miR-146a may be a potential target for asthma therapy.
Title: MicroRNA-146a promotes IgE class switch in B cells via upregulating 14-3-3? expression.

DEX can increase IOP in mouse eyes and concurrently downregulate 14-3-3 zeta protein expression in mouse TM
Title: Expression of 14-3-3 Zeta Protein in Dexamethasone-Treated Mice and Human TM-1 Cells.

When taken together these findings demonstrate novel roles of 14-3-3zeta in the regulation of glucose homeostasis and suggest that modulating 14-3-3zeta levels in intestinal L cells may have beneficial metabolic effects through GLP-1-dependent mechanisms.
Title: Ywhaz/14-3-3? Deletion Improves Glucose Tolerance Through a GLP-1-Dependent Mechanism.

Results indicate that HuR induces 14-3-3zeta translation via interaction with its 3' UTR and that 14-3-3zeta is necessary for stimulation of intestinal epithelial cell migration after wounding.
Title: Posttranscriptional regulation of 14-3-3? by RNA-binding protein HuR modulating intestinal epithelial restitution after wounding.

The data obtained from the 14-3-3epsilon/14-3-3zeta/Wnt1-Cre mice strongly indicate the importance of 14-3-3 proteins in the development of melanocyte lineages.
Title: Deficiency of 14-3-3? and 14-3-3? by the Wnt1 promoter-driven Cre recombinase results in pigmentation defects.

The following Ywhaz gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ywhaz cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu05634	NM_001253807.1 Latest version!	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu05631	NM_011740.3 Latest version!	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu05631	NM_001253806.1 Latest version!	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu05631	NM_001253805.1 Latest version!	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu05631	NM_001356569.1 Latest version!	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu05631	XM_011245352.2 Latest version!	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu05631	XM_030248527.1 Latest version!	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu05631	XM_011245352.1	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ywhaz ( NM_001253807.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001240736.1 Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu05634
Clone ID Related Accession (Same CDS sequence)	NM_001253807.1
Accession Version	NM_001253807.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Mus musculus(house mouse)
Product	14-3-3 protein zeta/delta isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC138604.5. Transcript Variant: This variant (4) differs in the 5' UTR and lacks a portion of the 5' coding region, which results in a downstream AUG start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: SRR1660813.159433.1, SRR1660815.47175.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMN01164131, SAMN01164139 [ECO:0000350] ##Evidence-Data-END##

ATGGCAGCCT GCATGAAGTC TGTCACTGAG CAGGGAGCTG AGCTGTCGAA TGAGGAGAGA 
AACCTTCTCT CTGTTGCTTA TAAAAACGTT GTAGGAGCCC GTAGGTCATC GTGGAGGGTC 
GTCTCAAGTA TTGAGCAGAA GACGGAAGGT GCTGAGAAAA AGCAGCAGAT GGCTCGAGAA 
TACAGAGAGA AGATCGAGAC GGAGCTGCGT GACATCTGCA ACGATGTACT GTCTCTTTTG 
GAAAAGTTCT TGATCCCCAA TGCTTCGCAA CCAGAAAGCA AAGTCTTCTA TTTGAAAATG 
AAGGGTGACT ACTACCGTTA CTTGGCCGAG GTTGCTGCTG GTGATGACAA GAAAGGAATT 
GTGGACCAGT CACAGCAAGC ATACCAAGAA GCATTTGAAA TCAGCAAAAA GGAGATGCAG 
CCGACACACC CCATCAGACT GGGTCTGGCC CTCAACTTCT CTGTGTTCTA TTACGAGATC 
CTGAACTCCC CAGAGAAAGC CTGCTCTCTT GCAAAAACAG CTTTCGATGA AGCCATTGCT 
GAACTTGATA CATTAAGTGA AGAGTCGTAC AAAGACAGCA CGCTAATAAT GCAGTTACTG 
AGAGACAACT TAACATTGTG GACATCGGAT ACCCAAGGAG ATGAAGCAGA AGCAGGAGAA 
GGAGGGGAAA ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001240736.1
CDS	29..703
Translation	MAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQPESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN

Target ORF information:

RefSeq Version	NM_001253807.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001253807.1

ORF Insert Sequence:

ATGGCAGCCT GCATGAAGTC TGTCACTGAG CAGGGAGCTG AGCTGTCGAA TGAGGAGAGA 
AACCTTCTCT CTGTTGCTTA TAAAAACGTT GTAGGAGCCC GTAGGTCATC GTGGAGGGTC 
GTCTCAAGTA TTGAGCAGAA GACGGAAGGT GCTGAGAAAA AGCAGCAGAT GGCTCGAGAA 
TACAGAGAGA AGATCGAGAC GGAGCTGCGT GACATCTGCA ACGATGTACT GTCTCTTTTG 
GAAAAGTTCT TGATCCCCAA TGCTTCGCAA CCAGAAAGCA AAGTCTTCTA TTTGAAAATG 
AAGGGTGACT ACTACCGTTA CTTGGCCGAG GTTGCTGCTG GTGATGACAA GAAAGGAATT 
GTGGACCAGT CACAGCAAGC ATACCAAGAA GCATTTGAAA TCAGCAAAAA GGAGATGCAG 
CCGACACACC CCATCAGACT GGGTCTGGCC CTCAACTTCT CTGTGTTCTA TTACGAGATC 
CTGAACTCCC CAGAGAAAGC CTGCTCTCTT GCAAAAACAG CTTTCGATGA AGCCATTGCT 
GAACTTGATA CATTAAGTGA AGAGTCGTAC AAAGACAGCA CGCTAATAAT GCAGTTACTG 
AGAGACAACT TAACATTGTG GACATCGGAT ACCCAAGGAG ATGAAGCAGA AGCAGGAGAA 
GGAGGGGAAA ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ywhaz ( NM_001356569.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001343498.1 Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OMu05631
Clone ID Related Accession (Same CDS sequence)	XM_030248527.1 , NM_001356569.1 , NM_001253805.1 , XM_011245352.1 , NM_001253806.1 , XM_011245352.2 , NM_011740.3
Accession Version	NM_001356569.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	14-3-3 protein zeta/delta isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC138604.5. On Oct 12, 2017 this sequence version replaced XM_011245352.2. Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 1. Variants 1-3 and 5 encode the same isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660815.164396.1, SRR1660813.59434.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGATAAAA ATGAGCTGGT GCAGAAGGCC AAGCTGGCCG AGCAGGCAGA GCGATATGAT 
GACATGGCAG CCTGCATGAA GTCTGTCACT GAGCAGGGAG CTGAGCTGTC GAATGAGGAG 
AGAAACCTTC TCTCTGTTGC TTATAAAAAC GTTGTAGGAG CCCGTAGGTC ATCGTGGAGG 
GTCGTCTCAA GTATTGAGCA GAAGACGGAA GGTGCTGAGA AAAAGCAGCA GATGGCTCGA 
GAATACAGAG AGAAGATCGA GACGGAGCTG CGTGACATCT GCAACGATGT ACTGTCTCTT 
TTGGAAAAGT TCTTGATCCC CAATGCTTCG CAACCAGAAA GCAAAGTCTT CTATTTGAAA 
ATGAAGGGTG ACTACTACCG TTACTTGGCC GAGGTTGCTG CTGGTGATGA CAAGAAAGGA 
ATTGTGGACC AGTCACAGCA AGCATACCAA GAAGCATTTG AAATCAGCAA AAAGGAGATG 
CAGCCGACAC ACCCCATCAG ACTGGGTCTG GCCCTCAACT TCTCTGTGTT CTATTACGAG 
ATCCTGAACT CCCCAGAGAA AGCCTGCTCT CTTGCAAAAA CAGCTTTCGA TGAAGCCATT 
GCTGAACTTG ATACATTAAG TGAAGAGTCG TACAAAGACA GCACGCTAAT AATGCAGTTA 
CTGAGAGACA ACTTAACATT GTGGACATCG GATACCCAAG GAGATGAAGC AGAAGCAGGA 
GAAGGAGGGG AAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001343498.1
CDS	606..1343
Translation	MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQPESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN

Target ORF information:

RefSeq Version	NM_001356569.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001356569.1

ORF Insert Sequence:

ATGGATAAAA ATGAGCTGGT GCAGAAGGCC AAGCTGGCCG AGCAGGCAGA GCGATATGAT 
GACATGGCAG CCTGCATGAA GTCTGTCACT GAGCAGGGAG CTGAGCTGTC GAATGAGGAG 
AGAAACCTTC TCTCTGTTGC TTATAAAAAC GTTGTAGGAG CCCGTAGGTC ATCGTGGAGG 
GTCGTCTCAA GTATTGAGCA GAAGACGGAA GGTGCTGAGA AAAAGCAGCA GATGGCTCGA 
GAATACAGAG AGAAGATCGA GACGGAGCTG CGTGACATCT GCAACGATGT ACTGTCTCTT 
TTGGAAAAGT TCTTGATCCC CAATGCTTCG CAACCAGAAA GCAAAGTCTT CTATTTGAAA 
ATGAAGGGTG ACTACTACCG TTACTTGGCC GAGGTTGCTG CTGGTGATGA CAAGAAAGGA 
ATTGTGGACC AGTCACAGCA AGCATACCAA GAAGCATTTG AAATCAGCAA AAAGGAGATG 
CAGCCGACAC ACCCCATCAG ACTGGGTCTG GCCCTCAACT TCTCTGTGTT CTATTACGAG 
ATCCTGAACT CCCCAGAGAA AGCCTGCTCT CTTGCAAAAA CAGCTTTCGA TGAAGCCATT 
GCTGAACTTG ATACATTAAG TGAAGAGTCG TACAAAGACA GCACGCTAAT AATGCAGTTA 
CTGAGAGACA ACTTAACATT GTGGACATCG GATACCCAAG GAGATGAAGC AGAAGCAGGA 
GAAGGAGGGG AAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ywhaz ( NM_001253805.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001240734.1 Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu05631
Clone ID Related Accession (Same CDS sequence)	XM_030248527.1 , NM_001356569.1 , NM_001253805.1 , XM_011245352.1 , NM_001253806.1 , XM_011245352.2 , NM_011740.3
Accession Version	NM_001253805.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	14-3-3 protein zeta/delta isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB652039.1, AK083368.1, BC050891.1, AK003664.1, AA277102.1 and BQ833188.1. Transcript Variant: This variant (2) lacks an internal exon in the 5' UTR, compared to variant 1. Variants 1-3 and 5 encode the same isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660813.243683.1, SRR1660821.85482.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164139 [ECO:0000348] ##Evidence-Data-END##

ATGGATAAAA ATGAGCTGGT GCAGAAGGCC AAGCTGGCCG AGCAGGCAGA GCGATATGAT 
GACATGGCAG CCTGCATGAA GTCTGTCACT GAGCAGGGAG CTGAGCTGTC GAATGAGGAG 
AGAAACCTTC TCTCTGTTGC TTATAAAAAC GTTGTAGGAG CCCGTAGGTC ATCGTGGAGG 
GTCGTCTCAA GTATTGAGCA GAAGACGGAA GGTGCTGAGA AAAAGCAGCA GATGGCTCGA 
GAATACAGAG AGAAGATCGA GACGGAGCTG CGTGACATCT GCAACGATGT ACTGTCTCTT 
TTGGAAAAGT TCTTGATCCC CAATGCTTCG CAACCAGAAA GCAAAGTCTT CTATTTGAAA 
ATGAAGGGTG ACTACTACCG TTACTTGGCC GAGGTTGCTG CTGGTGATGA CAAGAAAGGA 
ATTGTGGACC AGTCACAGCA AGCATACCAA GAAGCATTTG AAATCAGCAA AAAGGAGATG 
CAGCCGACAC ACCCCATCAG ACTGGGTCTG GCCCTCAACT TCTCTGTGTT CTATTACGAG 
ATCCTGAACT CCCCAGAGAA AGCCTGCTCT CTTGCAAAAA CAGCTTTCGA TGAAGCCATT 
GCTGAACTTG ATACATTAAG TGAAGAGTCG TACAAAGACA GCACGCTAAT AATGCAGTTA 
CTGAGAGACA ACTTAACATT GTGGACATCG GATACCCAAG GAGATGAAGC AGAAGCAGGA 
GAAGGAGGGG AAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001240734.1
CDS	406..1143
Translation	MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQPESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN

Target ORF information:

RefSeq Version	NM_001253805.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001253805.1

ORF Insert Sequence:

ATGGATAAAA ATGAGCTGGT GCAGAAGGCC AAGCTGGCCG AGCAGGCAGA GCGATATGAT 
GACATGGCAG CCTGCATGAA GTCTGTCACT GAGCAGGGAG CTGAGCTGTC GAATGAGGAG 
AGAAACCTTC TCTCTGTTGC TTATAAAAAC GTTGTAGGAG CCCGTAGGTC ATCGTGGAGG 
GTCGTCTCAA GTATTGAGCA GAAGACGGAA GGTGCTGAGA AAAAGCAGCA GATGGCTCGA 
GAATACAGAG AGAAGATCGA GACGGAGCTG CGTGACATCT GCAACGATGT ACTGTCTCTT 
TTGGAAAAGT TCTTGATCCC CAATGCTTCG CAACCAGAAA GCAAAGTCTT CTATTTGAAA 
ATGAAGGGTG ACTACTACCG TTACTTGGCC GAGGTTGCTG CTGGTGATGA CAAGAAAGGA 
ATTGTGGACC AGTCACAGCA AGCATACCAA GAAGCATTTG AAATCAGCAA AAAGGAGATG 
CAGCCGACAC ACCCCATCAG ACTGGGTCTG GCCCTCAACT TCTCTGTGTT CTATTACGAG 
ATCCTGAACT CCCCAGAGAA AGCCTGCTCT CTTGCAAAAA CAGCTTTCGA TGAAGCCATT 
GCTGAACTTG ATACATTAAG TGAAGAGTCG TACAAAGACA GCACGCTAAT AATGCAGTTA 
CTGAGAGACA ACTTAACATT GTGGACATCG GATACCCAAG GAGATGAAGC AGAAGCAGGA 
GAAGGAGGGG AAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ywhaz ( NM_001253806.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001240735.1 Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu05631
Clone ID Related Accession (Same CDS sequence)	XM_030248527.1 , NM_001356569.1 , NM_001253805.1 , XM_011245352.1 , NM_001253806.1 , XM_011245352.2 , NM_011740.3
Accession Version	NM_001253806.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	14-3-3 protein zeta/delta isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CF172373.1, BC050891.1, AK003664.1, AA277102.1 and BQ833188.1. Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-3 and 5 encode the same isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: SRR1660815.47175.1, SRR1660817.238121.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGATAAAA ATGAGCTGGT GCAGAAGGCC AAGCTGGCCG AGCAGGCAGA GCGATATGAT 
GACATGGCAG CCTGCATGAA GTCTGTCACT GAGCAGGGAG CTGAGCTGTC GAATGAGGAG 
AGAAACCTTC TCTCTGTTGC TTATAAAAAC GTTGTAGGAG CCCGTAGGTC ATCGTGGAGG 
GTCGTCTCAA GTATTGAGCA GAAGACGGAA GGTGCTGAGA AAAAGCAGCA GATGGCTCGA 
GAATACAGAG AGAAGATCGA GACGGAGCTG CGTGACATCT GCAACGATGT ACTGTCTCTT 
TTGGAAAAGT TCTTGATCCC CAATGCTTCG CAACCAGAAA GCAAAGTCTT CTATTTGAAA 
ATGAAGGGTG ACTACTACCG TTACTTGGCC GAGGTTGCTG CTGGTGATGA CAAGAAAGGA 
ATTGTGGACC AGTCACAGCA AGCATACCAA GAAGCATTTG AAATCAGCAA AAAGGAGATG 
CAGCCGACAC ACCCCATCAG ACTGGGTCTG GCCCTCAACT TCTCTGTGTT CTATTACGAG 
ATCCTGAACT CCCCAGAGAA AGCCTGCTCT CTTGCAAAAA CAGCTTTCGA TGAAGCCATT 
GCTGAACTTG ATACATTAAG TGAAGAGTCG TACAAAGACA GCACGCTAAT AATGCAGTTA 
CTGAGAGACA ACTTAACATT GTGGACATCG GATACCCAAG GAGATGAAGC AGAAGCAGGA 
GAAGGAGGGG AAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001240735.1
CDS	131..868
Translation	MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQPESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN

Target ORF information:

RefSeq Version	NM_001253806.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001253806.1

ORF Insert Sequence:

ATGGATAAAA ATGAGCTGGT GCAGAAGGCC AAGCTGGCCG AGCAGGCAGA GCGATATGAT 
GACATGGCAG CCTGCATGAA GTCTGTCACT GAGCAGGGAG CTGAGCTGTC GAATGAGGAG 
AGAAACCTTC TCTCTGTTGC TTATAAAAAC GTTGTAGGAG CCCGTAGGTC ATCGTGGAGG 
GTCGTCTCAA GTATTGAGCA GAAGACGGAA GGTGCTGAGA AAAAGCAGCA GATGGCTCGA 
GAATACAGAG AGAAGATCGA GACGGAGCTG CGTGACATCT GCAACGATGT ACTGTCTCTT 
TTGGAAAAGT TCTTGATCCC CAATGCTTCG CAACCAGAAA GCAAAGTCTT CTATTTGAAA 
ATGAAGGGTG ACTACTACCG TTACTTGGCC GAGGTTGCTG CTGGTGATGA CAAGAAAGGA 
ATTGTGGACC AGTCACAGCA AGCATACCAA GAAGCATTTG AAATCAGCAA AAAGGAGATG 
CAGCCGACAC ACCCCATCAG ACTGGGTCTG GCCCTCAACT TCTCTGTGTT CTATTACGAG 
ATCCTGAACT CCCCAGAGAA AGCCTGCTCT CTTGCAAAAA CAGCTTTCGA TGAAGCCATT 
GCTGAACTTG ATACATTAAG TGAAGAGTCG TACAAAGACA GCACGCTAAT AATGCAGTTA 
CTGAGAGACA ACTTAACATT GTGGACATCG GATACCCAAG GAGATGAAGC AGAAGCAGGA 
GAAGGAGGGG AAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ywhaz ( NM_011740.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035870.1 Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu05631
Clone ID Related Accession (Same CDS sequence)	XM_030248527.1 , NM_001356569.1 , NM_001253805.1 , XM_011245352.1 , NM_001253806.1 , XM_011245352.2 , NM_011740.3
Accession Version	NM_011740.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	14-3-3 protein zeta/delta isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB652039.1, AK150381.1, AC138604.5 and BQ833188.1. On Dec 12, 2009 this sequence version replaced NM_011740.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1-3 and 5 encode the same isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660813.207661.1, SRR1660815.20386.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGATAAAA ATGAGCTGGT GCAGAAGGCC AAGCTGGCCG AGCAGGCAGA GCGATATGAT 
GACATGGCAG CCTGCATGAA GTCTGTCACT GAGCAGGGAG CTGAGCTGTC GAATGAGGAG 
AGAAACCTTC TCTCTGTTGC TTATAAAAAC GTTGTAGGAG CCCGTAGGTC ATCGTGGAGG 
GTCGTCTCAA GTATTGAGCA GAAGACGGAA GGTGCTGAGA AAAAGCAGCA GATGGCTCGA 
GAATACAGAG AGAAGATCGA GACGGAGCTG CGTGACATCT GCAACGATGT ACTGTCTCTT 
TTGGAAAAGT TCTTGATCCC CAATGCTTCG CAACCAGAAA GCAAAGTCTT CTATTTGAAA 
ATGAAGGGTG ACTACTACCG TTACTTGGCC GAGGTTGCTG CTGGTGATGA CAAGAAAGGA 
ATTGTGGACC AGTCACAGCA AGCATACCAA GAAGCATTTG AAATCAGCAA AAAGGAGATG 
CAGCCGACAC ACCCCATCAG ACTGGGTCTG GCCCTCAACT TCTCTGTGTT CTATTACGAG 
ATCCTGAACT CCCCAGAGAA AGCCTGCTCT CTTGCAAAAA CAGCTTTCGA TGAAGCCATT 
GCTGAACTTG ATACATTAAG TGAAGAGTCG TACAAAGACA GCACGCTAAT AATGCAGTTA 
CTGAGAGACA ACTTAACATT GTGGACATCG GATACCCAAG GAGATGAAGC AGAAGCAGGA 
GAAGGAGGGG AAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035870.1
CDS	603..1340
Translation	MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQPESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN

Target ORF information:

RefSeq Version	NM_011740.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011740.3

ORF Insert Sequence:

ATGGATAAAA ATGAGCTGGT GCAGAAGGCC AAGCTGGCCG AGCAGGCAGA GCGATATGAT 
GACATGGCAG CCTGCATGAA GTCTGTCACT GAGCAGGGAG CTGAGCTGTC GAATGAGGAG 
AGAAACCTTC TCTCTGTTGC TTATAAAAAC GTTGTAGGAG CCCGTAGGTC ATCGTGGAGG 
GTCGTCTCAA GTATTGAGCA GAAGACGGAA GGTGCTGAGA AAAAGCAGCA GATGGCTCGA 
GAATACAGAG AGAAGATCGA GACGGAGCTG CGTGACATCT GCAACGATGT ACTGTCTCTT 
TTGGAAAAGT TCTTGATCCC CAATGCTTCG CAACCAGAAA GCAAAGTCTT CTATTTGAAA 
ATGAAGGGTG ACTACTACCG TTACTTGGCC GAGGTTGCTG CTGGTGATGA CAAGAAAGGA 
ATTGTGGACC AGTCACAGCA AGCATACCAA GAAGCATTTG AAATCAGCAA AAAGGAGATG 
CAGCCGACAC ACCCCATCAG ACTGGGTCTG GCCCTCAACT TCTCTGTGTT CTATTACGAG 
ATCCTGAACT CCCCAGAGAA AGCCTGCTCT CTTGCAAAAA CAGCTTTCGA TGAAGCCATT 
GCTGAACTTG ATACATTAAG TGAAGAGTCG TACAAAGACA GCACGCTAAT AATGCAGTTA 
CTGAGAGACA ACTTAACATT GTGGACATCG GATACCCAAG GAGATGAAGC AGAAGCAGGA 
GAAGGAGGGG AAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ywhaz ( XM_030248527.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030104387.1 Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu05631
Clone ID Related Accession (Same CDS sequence)	XM_030248527.1 , NM_001356569.1 , NM_001253805.1 , XM_011245352.1 , NM_001253806.1 , XM_011245352.2 , NM_011740.3
Accession Version	XM_030248527.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	14-3-3 protein zeta/delta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATAAAA ATGAGCTGGT GCAGAAGGCC AAGCTGGCCG AGCAGGCAGA GCGATATGAT 
GACATGGCAG CCTGCATGAA GTCTGTCACT GAGCAGGGAG CTGAGCTGTC GAATGAGGAG 
AGAAACCTTC TCTCTGTTGC TTATAAAAAC GTTGTAGGAG CCCGTAGGTC ATCGTGGAGG 
GTCGTCTCAA GTATTGAGCA GAAGACGGAA GGTGCTGAGA AAAAGCAGCA GATGGCTCGA 
GAATACAGAG AGAAGATCGA GACGGAGCTG CGTGACATCT GCAACGATGT ACTGTCTCTT 
TTGGAAAAGT TCTTGATCCC CAATGCTTCG CAACCAGAAA GCAAAGTCTT CTATTTGAAA 
ATGAAGGGTG ACTACTACCG TTACTTGGCC GAGGTTGCTG CTGGTGATGA CAAGAAAGGA 
ATTGTGGACC AGTCACAGCA AGCATACCAA GAAGCATTTG AAATCAGCAA AAAGGAGATG 
CAGCCGACAC ACCCCATCAG ACTGGGTCTG GCCCTCAACT TCTCTGTGTT CTATTACGAG 
ATCCTGAACT CCCCAGAGAA AGCCTGCTCT CTTGCAAAAA CAGCTTTCGA TGAAGCCATT 
GCTGAACTTG ATACATTAAG TGAAGAGTCG TACAAAGACA GCACGCTAAT AATGCAGTTA 
CTGAGAGACA ACTTAACATT GTGGACATCG GATACCCAAG GAGATGAAGC AGAAGCAGGA 
GAAGGAGGGG AAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030104387.1
CDS	622..1359
Translation	MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQPESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN

Target ORF information:

RefSeq Version	XM_030248527.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030248527.1

ORF Insert Sequence:

ATGGATAAAA ATGAGCTGGT GCAGAAGGCC AAGCTGGCCG AGCAGGCAGA GCGATATGAT 
GACATGGCAG CCTGCATGAA GTCTGTCACT GAGCAGGGAG CTGAGCTGTC GAATGAGGAG 
AGAAACCTTC TCTCTGTTGC TTATAAAAAC GTTGTAGGAG CCCGTAGGTC ATCGTGGAGG 
GTCGTCTCAA GTATTGAGCA GAAGACGGAA GGTGCTGAGA AAAAGCAGCA GATGGCTCGA 
GAATACAGAG AGAAGATCGA GACGGAGCTG CGTGACATCT GCAACGATGT ACTGTCTCTT 
TTGGAAAAGT TCTTGATCCC CAATGCTTCG CAACCAGAAA GCAAAGTCTT CTATTTGAAA 
ATGAAGGGTG ACTACTACCG TTACTTGGCC GAGGTTGCTG CTGGTGATGA CAAGAAAGGA 
ATTGTGGACC AGTCACAGCA AGCATACCAA GAAGCATTTG AAATCAGCAA AAAGGAGATG 
CAGCCGACAC ACCCCATCAG ACTGGGTCTG GCCCTCAACT TCTCTGTGTT CTATTACGAG 
ATCCTGAACT CCCCAGAGAA AGCCTGCTCT CTTGCAAAAA CAGCTTTCGA TGAAGCCATT 
GCTGAACTTG ATACATTAAG TGAAGAGTCG TACAAAGACA GCACGCTAAT AATGCAGTTA 
CTGAGAGACA ACTTAACATT GTGGACATCG GATACCCAAG GAGATGAAGC AGAAGCAGGA 
GAAGGAGGGG AAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ywhaz ( XM_011245352.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011243654.1 Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu05631
Clone ID Related Accession (Same CDS sequence)	XM_030248527.1 , NM_001356569.1 , NM_001253805.1 , XM_011245352.1 , NM_001253806.1 , XM_011245352.2 , NM_011740.3
Accession Version	XM_011245352.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	14-3-3 protein zeta/delta isoform X1
Comment

ATGGATAAAA ATGAGCTGGT GCAGAAGGCC AAGCTGGCCG AGCAGGCAGA GCGATATGAT 
GACATGGCAG CCTGCATGAA GTCTGTCACT GAGCAGGGAG CTGAGCTGTC GAATGAGGAG 
AGAAACCTTC TCTCTGTTGC TTATAAAAAC GTTGTAGGAG CCCGTAGGTC ATCGTGGAGG 
GTCGTCTCAA GTATTGAGCA GAAGACGGAA GGTGCTGAGA AAAAGCAGCA GATGGCTCGA 
GAATACAGAG AGAAGATCGA GACGGAGCTG CGTGACATCT GCAACGATGT ACTGTCTCTT 
TTGGAAAAGT TCTTGATCCC CAATGCTTCG CAACCAGAAA GCAAAGTCTT CTATTTGAAA 
ATGAAGGGTG ACTACTACCG TTACTTGGCC GAGGTTGCTG CTGGTGATGA CAAGAAAGGA 
ATTGTGGACC AGTCACAGCA AGCATACCAA GAAGCATTTG AAATCAGCAA AAAGGAGATG 
CAGCCGACAC ACCCCATCAG ACTGGGTCTG GCCCTCAACT TCTCTGTGTT CTATTACGAG 
ATCCTGAACT CCCCAGAGAA AGCCTGCTCT CTTGCAAAAA CAGCTTTCGA TGAAGCCATT 
GCTGAACTTG ATACATTAAG TGAAGAGTCG TACAAAGACA GCACGCTAAT AATGCAGTTA 
CTGAGAGACA ACTTAACATT GTGGACATCG GATACCCAAG GAGATGAAGC AGAAGCAGGA 
GAAGGAGGGG AAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011243654.1
Translation	MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQPESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN

Target ORF information:

RefSeq Version	XM_011245352.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011245352.1

ORF Insert Sequence:

ATGGATAAAA ATGAGCTGGT GCAGAAGGCC AAGCTGGCCG AGCAGGCAGA GCGATATGAT 
GACATGGCAG CCTGCATGAA GTCTGTCACT GAGCAGGGAG CTGAGCTGTC GAATGAGGAG 
AGAAACCTTC TCTCTGTTGC TTATAAAAAC GTTGTAGGAG CCCGTAGGTC ATCGTGGAGG 
GTCGTCTCAA GTATTGAGCA GAAGACGGAA GGTGCTGAGA AAAAGCAGCA GATGGCTCGA 
GAATACAGAG AGAAGATCGA GACGGAGCTG CGTGACATCT GCAACGATGT ACTGTCTCTT 
TTGGAAAAGT TCTTGATCCC CAATGCTTCG CAACCAGAAA GCAAAGTCTT CTATTTGAAA 
ATGAAGGGTG ACTACTACCG TTACTTGGCC GAGGTTGCTG CTGGTGATGA CAAGAAAGGA 
ATTGTGGACC AGTCACAGCA AGCATACCAA GAAGCATTTG AAATCAGCAA AAAGGAGATG 
CAGCCGACAC ACCCCATCAG ACTGGGTCTG GCCCTCAACT TCTCTGTGTT CTATTACGAG 
ATCCTGAACT CCCCAGAGAA AGCCTGCTCT CTTGCAAAAA CAGCTTTCGA TGAAGCCATT 
GCTGAACTTG ATACATTAAG TGAAGAGTCG TACAAAGACA GCACGCTAAT AATGCAGTTA 
CTGAGAGACA ACTTAACATT GTGGACATCG GATACCCAAG GAGATGAAGC AGAAGCAGGA 
GAAGGAGGGG AAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ywhaz ( XM_011245352.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011243654.1 Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu05631
Clone ID Related Accession (Same CDS sequence)	XM_030248527.1 , NM_001356569.1 , NM_001253805.1 , XM_011245352.1 , NM_001253806.1 , XM_011245352.2 , NM_011740.3
Accession Version	XM_011245352.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	14-3-3 protein zeta/delta isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011245352.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATAAAA ATGAGCTGGT GCAGAAGGCC AAGCTGGCCG AGCAGGCAGA GCGATATGAT 
GACATGGCAG CCTGCATGAA GTCTGTCACT GAGCAGGGAG CTGAGCTGTC GAATGAGGAG 
AGAAACCTTC TCTCTGTTGC TTATAAAAAC GTTGTAGGAG CCCGTAGGTC ATCGTGGAGG 
GTCGTCTCAA GTATTGAGCA GAAGACGGAA GGTGCTGAGA AAAAGCAGCA GATGGCTCGA 
GAATACAGAG AGAAGATCGA GACGGAGCTG CGTGACATCT GCAACGATGT ACTGTCTCTT 
TTGGAAAAGT TCTTGATCCC CAATGCTTCG CAACCAGAAA GCAAAGTCTT CTATTTGAAA 
ATGAAGGGTG ACTACTACCG TTACTTGGCC GAGGTTGCTG CTGGTGATGA CAAGAAAGGA 
ATTGTGGACC AGTCACAGCA AGCATACCAA GAAGCATTTG AAATCAGCAA AAAGGAGATG 
CAGCCGACAC ACCCCATCAG ACTGGGTCTG GCCCTCAACT TCTCTGTGTT CTATTACGAG 
ATCCTGAACT CCCCAGAGAA AGCCTGCTCT CTTGCAAAAA CAGCTTTCGA TGAAGCCATT 
GCTGAACTTG ATACATTAAG TGAAGAGTCG TACAAAGACA GCACGCTAAT AATGCAGTTA 
CTGAGAGACA ACTTAACATT GTGGACATCG GATACCCAAG GAGATGAAGC AGAAGCAGGA 
GAAGGAGGGG AAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011243654.1
CDS	358..1095
Translation	MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQPESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN

Target ORF information:

RefSeq Version	XM_011245352.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011245352.2

ORF Insert Sequence:

ATGGATAAAA ATGAGCTGGT GCAGAAGGCC AAGCTGGCCG AGCAGGCAGA GCGATATGAT 
GACATGGCAG CCTGCATGAA GTCTGTCACT GAGCAGGGAG CTGAGCTGTC GAATGAGGAG 
AGAAACCTTC TCTCTGTTGC TTATAAAAAC GTTGTAGGAG CCCGTAGGTC ATCGTGGAGG 
GTCGTCTCAA GTATTGAGCA GAAGACGGAA GGTGCTGAGA AAAAGCAGCA GATGGCTCGA 
GAATACAGAG AGAAGATCGA GACGGAGCTG CGTGACATCT GCAACGATGT ACTGTCTCTT 
TTGGAAAAGT TCTTGATCCC CAATGCTTCG CAACCAGAAA GCAAAGTCTT CTATTTGAAA 
ATGAAGGGTG ACTACTACCG TTACTTGGCC GAGGTTGCTG CTGGTGATGA CAAGAAAGGA 
ATTGTGGACC AGTCACAGCA AGCATACCAA GAAGCATTTG AAATCAGCAA AAAGGAGATG 
CAGCCGACAC ACCCCATCAG ACTGGGTCTG GCCCTCAACT TCTCTGTGTT CTATTACGAG 
ATCCTGAACT CCCCAGAGAA AGCCTGCTCT CTTGCAAAAA CAGCTTTCGA TGAAGCCATT 
GCTGAACTTG ATACATTAAG TGAAGAGTCG TACAAAGACA GCACGCTAAT AATGCAGTTA 
CTGAGAGACA ACTTAACATT GTGGACATCG GATACCCAAG GAGATGAAGC AGAAGCAGGA 
GAAGGAGGGG AAAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MicroRNA-146a promotes IgE class switch in B cells via upregulating 14-3-3? expression.
Molecular immunology92180-189(2017 Dec)
Li F,Huang Y,Huang YY,Kuang YS,Wei YJ,Xiang L,Zhang XJ,Jia ZC,Jiang S,Li JY,Wan Y

14-3-3? loss impedes oncogene-induced mammary tumorigenesis and metastasis by attenuating oncogenic signaling.
American journal of cancer research7(8)1654-1664(2017)
Joshi S,Yang J,Wang Q,Li P,Wang H,Zhang Q,Xiong Y,Pickering BF,Parker-Thornburg J,Behringer RR,Yu D

14-3-3? loss leads to neonatal lethality by microRNA-126 downregulation-mediated developmental defects in lung vasculature.
Cell & bioscience758(2017)
Yang J,Joshi S,Wang Q,Li P,Wang H,Xiong Y,Xiao Y,Wang J,Parker-Thornburg J,Behringer RR,Yu D

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Ywhaz cDNA ORF clone, Mus musculus(house mouse)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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