Npbwr1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Npbwr1
Entrez Gene ID	226304
Full Name	neuropeptides B/W receptor 1
Synonyms	Gpr7,Nbpwr1
General protein information	Preferred Names neuropeptides B/W receptor 1 Names neuropeptides B/W receptor type 1 G protein-coupled receptor 7
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 A1

mRNA and Protein(s)

mRNA	Protein	Name
NM_010342.1	NP_034472.1	neuropeptides B/W receptor type 1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Npbwr1	NP_034472.1
Pan troglodytes (chimpanzee)	NPBWR1	XP_003311788.1
Bos taurus (cattle)	NPBWR1	NP_776499.1
Gallus gallus (chicken)	NPBWR1	XP_004939913.1
Homo sapiens (human)	NPBWR1	NP_005276.2
Danio rerio (zebrafish)	LOC556451	NP_001124241.1
Xenopus tropicalis (tropical clawed frog)	npbwr1	XP_002934151.2
Canis lupus familiaris (dog)	NPBWR1	XP_544078.2
Rattus norvegicus (Norway rat)	Npbwr1	NP_001014784.1
	NPBWR1	XP_001102797.1

Gene Ontology
Bibliography

Related articles in PubMed

Critical role of neuropeptides B/W receptor 1 signaling in social behavior and fear memory.
Nagata-Kuroiwa R, Furutani N, Hara J, Hondo M, Ishii M, Abe T, Mieda M, Tsujino N, Motoike T, Yanagawa Y, Kuwaki T, Yamamoto M, Yanagisawa M, Sakurai T
PloS one6(2)e16972(2011 Feb)

Circadian characteristics of mice depleted with GPR7.
Uchio N, Doi M, Matsuo M, Yamazaki F, Mizoro Y, Hondo M, Sakurai T, Okamura H
Biomedical research (Tokyo, Japan)30(6)357-64(2009 Dec)

Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity.
Ishii M, Fei H, Friedman JM
Proceedings of the National Academy of Sciences of the United States of America100(18)10540-5(2003 Sep)

The cloning and chromosomal mapping of two novel human opioid-somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain.
O'Dowd BF, Scheideler MA, Nguyen T, Cheng R, Rasmussen JS, Marchese A, Zastawny R, Heng HH, Tsui LC, Shi X
Genomics28(1)84-91(1995 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Important roles of NPBWR1 in regulating amygdala function during physical and social stress.
Title: Critical role of neuropeptides B/W receptor 1 signaling in social behavior and fear memory.

data demonstrate that GPR7 mRNA showed a significant circadian rhythm in the suprachiasmatic nucleus showing a peak at early subjective night in both light-dark and constant dark
Title: Circadian characteristics of mice depleted with GPR7.

role for GPR7 and its endogenous ligands, neuropeptide B and neuropeptide W, in regulating energy homeostasis.
Title: Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity.

The following Npbwr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Npbwr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58573	NM_010342.1 Latest version!	Mus musculus neuropeptides B/W receptor 1 (Npbwr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Npbwr1 ( NM_010342.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034472.1 Mus musculus neuropeptides B/W receptor 1 (Npbwr1), mRNA.

Price & Availability↑

CloneID	OMu58573
Clone ID Related Accession (Same CDS sequence)	NM_010342.1
Accession Version	NM_010342.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	neuropeptides B/W receptor type 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC118196.12. On or before Jul 25, 2009 this sequence version replaced XM_912251.2, XM_136404.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript is intronless :: AK138357.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCATAACT TAACGCTTTT CGAGTCTGGA GGGGACAACG TGTCTTGCGG CGGCTCATCT 
TTGGGCTGTC CCAACGGGTC CAGCCTGGCT CCTCTGCCGC TGCCGCAGCC ACTGGCGGTA 
GCAGTGCCTG TCGTCTACGG GGTAATTTGC GCCGTGGGAC TGGCTGGCAA CTCTGCGGTG 
CTGTACGTAC TGCTGCGCAC GCCGCGCATG AAGACTGTCA CCAACGTGTT CATCCTCAAC 
CTGGCTATCG CCGATGAGCT CTTCACCCTC GTGCTGCCCA TCAACATCGC GGACTTCCTG 
CTGAGGCGCT GGCCCTTCGG GGAGGTCATG TGCAAGCTCA TTGTAGCCGT CGACCAGTAC 
AACACTTTCT CTAGCCTCTA CTTCCTCGCC GTCATGAGCG CCGACCGATA CCTGGTGGTT 
CTGGCCACAG CAGAGTCGCG CCGGGTGTCC GGGCGCACTT ACGGTGCAGC GCGTGCTGTC 
AGTCTGGCGG TGTGGGCGCT GGTGACGCTG GTCGTGCTGC CCTTTGCGGT ATTCGCTCGG 
CTGGACGAGG AGCAGGGTCG GCGCCAGTGC GTGCTGGTCT TCCCGCAGCC CGAGGCCTTC 
TGGTGGCGTG CCAGCCGTCT CTACACACTA GTATTGGGCT TTGCCATCCC GGTGACCACC 
ATCTGTGCTC TCTATACCAC TCTGCTCTGC CGACTGCGTG CTATCCAGCT AGATAGCCAC 
GCCAAGGCCC TGGATCGTGC CAAGAAGCGC GTGACCTTGT TGGTGGCGGC GATTCTGGCT 
GTGTGCCTCC TCTGCTGGAC GCCTTATCAC CTGAGTACCA TAGTGGCCCT CACCACCGAC 
CTCCCGCAAA CGCCGCTGGT CATCGGCATC TCTTACTTCA TCACCAGCCT GAGCTATGCT 
AACAGCTGCC TCAACCCTTT CCTCTATGCC TTCCTGGACG ACAGCTTCCG CAGAAGCCTC 
CGGCAATTGG TGTCATGCCG TTCAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034472.1
CDS	106..1095
Translation	MHNLTLFESGGDNVSCGGSSLGCPNGSSLAPLPLPQPLAVAVPVVYGVICAVGLAGNSAVLYVLLRTPRMKTVTNVFILNLAIADELFTLVLPINIADFLLRRWPFGEVMCKLIVAVDQYNTFSSLYFLAVMSADRYLVVLATAESRRVSGRTYGAARAVSLAVWALVTLVVLPFAVFARLDEEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVTTICALYTTLLCRLRAIQLDSHAKALDRAKKRVTLLVAAILAVCLLCWTPYHLSTIVALTTDLPQTPLVIGISYFITSLSYANSCLNPFLYAFLDDSFRRSLRQLVSCRSA

Target ORF information:

RefSeq Version	NM_010342.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus neuropeptides B/W receptor 1 (Npbwr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010342.1

ORF Insert Sequence:

ATGCATAACT TAACGCTTTT CGAGTCTGGA GGGGACAACG TGTCTTGCGG CGGCTCATCT 
TTGGGCTGTC CCAACGGGTC CAGCCTGGCT CCTCTGCCGC TGCCGCAGCC ACTGGCGGTA 
GCAGTGCCTG TCGTCTACGG GGTAATTTGC GCCGTGGGAC TGGCTGGCAA CTCTGCGGTG 
CTGTACGTAC TGCTGCGCAC GCCGCGCATG AAGACTGTCA CCAACGTGTT CATCCTCAAC 
CTGGCTATCG CCGATGAGCT CTTCACCCTC GTGCTGCCCA TCAACATCGC GGACTTCCTG 
CTGAGGCGCT GGCCCTTCGG GGAGGTCATG TGCAAGCTCA TTGTAGCCGT CGACCAGTAC 
AACACTTTCT CTAGCCTCTA CTTCCTCGCC GTCATGAGCG CCGACCGATA CCTGGTGGTT 
CTGGCCACAG CAGAGTCGCG CCGGGTGTCC GGGCGCACTT ACGGTGCAGC GCGTGCTGTC 
AGTCTGGCGG TGTGGGCGCT GGTGACGCTG GTCGTGCTGC CCTTTGCGGT ATTCGCTCGG 
CTGGACGAGG AGCAGGGTCG GCGCCAGTGC GTGCTGGTCT TCCCGCAGCC CGAGGCCTTC 
TGGTGGCGTG CCAGCCGTCT CTACACACTA GTATTGGGCT TTGCCATCCC GGTGACCACC 
ATCTGTGCTC TCTATACCAC TCTGCTCTGC CGACTGCGTG CTATCCAGCT AGATAGCCAC 
GCCAAGGCCC TGGATCGTGC CAAGAAGCGC GTGACCTTGT TGGTGGCGGC GATTCTGGCT 
GTGTGCCTCC TCTGCTGGAC GCCTTATCAC CTGAGTACCA TAGTGGCCCT CACCACCGAC 
CTCCCGCAAA CGCCGCTGGT CATCGGCATC TCTTACTTCA TCACCAGCCT GAGCTATGCT 
AACAGCTGCC TCAACCCTTT CCTCTATGCC TTCCTGGACG ACAGCTTCCG CAGAAGCCTC 
CGGCAATTGG TGTCATGCCG TTCAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Critical role of neuropeptides B/W receptor 1 signaling in social behavior and fear memory.
PloS one6(2)e16972(2011 Feb)
Nagata-Kuroiwa R,Furutani N,Hara J,Hondo M,Ishii M,Abe T,Mieda M,Tsujino N,Motoike T,Yanagawa Y,Kuwaki T,Yamamoto M,Yanagisawa M,Sakurai T

Circadian characteristics of mice depleted with GPR7.
Biomedical research (Tokyo, Japan)30(6)357-64(2009 Dec)
Uchio N,Doi M,Matsuo M,Yamazaki F,Mizoro Y,Hondo M,Sakurai T,Okamura H

Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity.
Proceedings of the National Academy of Sciences of the United States of America100(18)10540-5(2003 Sep)
Ishii M,Fei H,Friedman JM

The cloning and chromosomal mapping of two novel human opioid-somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain.
Genomics28(1)84-91(1995 Jul)
O'Dowd BF,Scheideler MA,Nguyen T,Cheng R,Rasmussen JS,Marchese A,Zastawny R,Heng HH,Tsui LC,Shi X

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Npbwr1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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