H2-M10.5 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	H2-M10.5
Entrez Gene ID	224761
Full Name	histocompatibility 2, M region locus 10.5
Synonyms	6.9H
General protein information	Preferred Names histocompatibility 2, M region locus 10.5 Names histocompatibility 2, M region locus 10.5
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17 B1\|17 19.16 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_177637.3	NP_808305.2	histocompatibility 2, M region locus 10.5 precursor
XM_030249732.1	XP_030105592.1	histocompatibility 2, M region locus 10.5 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	H2-M10.1	NP_038572.3
Mus musculus (house mouse)	H2-M10.5	NP_808305.2
Mus musculus (house mouse)	H2-M10.6	NP_963905.1
Mus musculus (house mouse)	H2-M10.4	NP_808302.1
Mus musculus (house mouse)	H2-M10.2	NP_808591.1
Mus musculus (house mouse)	H2-M10.3	NP_963902.1

Gene Ontology
Bibliography

Related articles in PubMed

Functional expression of murine V2R pheromone receptors involves selective association with the M10 and M1 families of MHC class Ib molecules.
Loconto J, Papes F, Chang E, Stowers L, Jones EP, Takada T, Kum?novics A, Fischer Lindahl K, Dulac C
Cell112(5)607-18(2003 Mar)

Combinatorial coexpression of neural and immune multigene families in mouse vomeronasal sensory neurons.
Ishii T, Hirota J, Mombaerts P
Current biology : CB13(5)394-400(2003 Mar)

Characterization of two class I genes from the H2-M region: evidence for a new subfamily.
Arepalli SR, Jones EP, Howcroft TK, Carlo I, Wang C, Lindahl KF, Singer DS, Rudikoff S
Immunogenetics47(3)264-71(1998)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following H2-M10.5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the H2-M10.5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu06579	NM_177637.3 Latest version!	Mus musculus histocompatibility 2, M region locus 10.5 (H2-M10.5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu87173	XM_030249732.1 Latest version!	Mus musculus histocompatibility 2, M region locus 10.5 (H2-M10.5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

H2-M10.5 ( NM_177637.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_808305.2 Mus musculus histocompatibility 2, M region locus 10.5 (H2-M10.5), mRNA.

Price & Availability↑

CloneID	OMu06579
Clone ID Related Accession (Same CDS sequence)	NM_177637.3
Accession Version	NM_177637.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 993bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Mus musculus(house mouse)
Product	histocompatibility 2, M region locus 10.5 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY211082.1 and AF539601.1. On Sep 20, 2006 this sequence version replaced NM_177637.2. ##Evidence-Data-START## Transcript exon combination :: AY211082.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849383 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGAACC CTGGATGCTG CACACTCCTC CTCCTCTTGG TGGCCATGGA CCTGATCCAG 
TATTGTGCAG GCTCACACTG GCTGCAGACT TTCAACGCTG TGATTTTGGA GCCTGGCATG 
GTTAATTCCC GGTTCGTCCA CATTGGCTAT GTAGACTCTA TAGAGTATCA GAGATATGAC 
AGCAAAGAAC CAATTGCAGT TTTGCTACCT CGGGTTGCAT GGATGGAGCA GGTGCCAATG 
ACATATTGGA CCAGTGAGAC AGCAAGCGTT GCGGAATTGT CACAGCTAGA CAGACGAATT 
CTTCACTTCA TGGTGAACAA AAATGAACAA AGAATGGACG ATTATCACAC CCTGCAGGAA 
GTGTATGGCT GCAATGTGGC TAATGATGGG AGCTTCCTCG GCGGTCACTT CCGGCTCACC 
TACTATGGCT ATGATGACTT ATACCTGAAT GAGAACCTGA GCTCCTGGAT TGCACATGGA 
AACGCAGCTG AATATGTGAA GAGCAGGTGG GACGGTGAAG GTGATGCAGA AAGGTGGAAG 
ACTTACCTGC AAGGAGTGTG CGTGGAAAGG CTTCTTAGAT ACATGGTCCT TGGAAAGGAA 
GCATTGCTGC GCTCCGATGC CCCCCGAACA CATGTGACCC ACCATGTAAG ACCTGAAGGG 
AATGTCACCC TGAGGTGCTG GGCCCTGGGC TTCTACCCAG CTGACATAAC CATGACTTGG 
AAGAGGGATG GGAACAACCA CACCCAAGAC ATGGAGCTGC CAGACACCAG GCCTGCAGGG 
GATGGAACCT TCCAGAAGTG GGCAGCTGTG GTGGTTCCTT CTGGAGAAGA GCTGAGATAC 
ACATGTCATG TGCACCATAA AGGGTTACCT GAGCCTCTCA AGCTGAAATG GGAGCCTCCA 
CACACCATCC CCATCATAGC AATTCTCATC GGCCTGGTTC TTGGAACTTT GGTGGTGGGA 
ACTGTGGTCA TTTTTCTGGT GTGGAAGAAA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_808305.2
CDS	1..993
Translation	MRNPGCCTLLLLLVAMDLIQYCAGSHWLQTFNAVILEPGMVNSRFVHIGYVDSIEYQRYDSKEPIAVLLPRVAWMEQVPMTYWTSETASVAELSQLDRRILHFMVNKNEQRMDDYHTLQEVYGCNVANDGSFLGGHFRLTYYGYDDLYLNENLSSWIAHGNAAEYVKSRWDGEGDAERWKTYLQGVCVERLLRYMVLGKEALLRSDAPRTHVTHHVRPEGNVTLRCWALGFYPADITMTWKRDGNNHTQDMELPDTRPAGDGTFQKWAAVVVPSGEELRYTCHVHHKGLPEPLKLKWEPPHTIPIIAILIGLVLGTLVVGTVVIFLVWKK

Target ORF information:

RefSeq Version	NM_177637.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus histocompatibility 2, M region locus 10.5 (H2-M10.5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177637.3

ORF Insert Sequence:

ATGAGGAACC CTGGATGCTG CACACTCCTC CTCCTCTTGG TGGCCATGGA CCTGATCCAG 
TATTGTGCAG GCTCACACTG GCTGCAGACT TTCAACGCTG TGATTTTGGA GCCTGGCATG 
GTTAATTCCC GGTTCGTCCA CATTGGCTAT GTAGACTCTA TAGAGTATCA GAGATATGAC 
AGCAAAGAAC CAATTGCAGT TTTGCTACCT CGGGTTGCAT GGATGGAGCA GGTGCCAATG 
ACATATTGGA CCAGTGAGAC AGCAAGCGTT GCGGAATTGT CACAGCTAGA CAGACGAATT 
CTTCACTTCA TGGTGAACAA AAATGAACAA AGAATGGACG ATTATCACAC CCTGCAGGAA 
GTGTATGGCT GCAATGTGGC TAATGATGGG AGCTTCCTCG GCGGTCACTT CCGGCTCACC 
TACTATGGCT ATGATGACTT ATACCTGAAT GAGAACCTGA GCTCCTGGAT TGCACATGGA 
AACGCAGCTG AATATGTGAA GAGCAGGTGG GACGGTGAAG GTGATGCAGA AAGGTGGAAG 
ACTTACCTGC AAGGAGTGTG CGTGGAAAGG CTTCTTAGAT ACATGGTCCT TGGAAAGGAA 
GCATTGCTGC GCTCCGATGC CCCCCGAACA CATGTGACCC ACCATGTAAG ACCTGAAGGG 
AATGTCACCC TGAGGTGCTG GGCCCTGGGC TTCTACCCAG CTGACATAAC CATGACTTGG 
AAGAGGGATG GGAACAACCA CACCCAAGAC ATGGAGCTGC CAGACACCAG GCCTGCAGGG 
GATGGAACCT TCCAGAAGTG GGCAGCTGTG GTGGTTCCTT CTGGAGAAGA GCTGAGATAC 
ACATGTCATG TGCACCATAA AGGGTTACCT GAGCCTCTCA AGCTGAAATG GGAGCCTCCA 
CACACCATCC CCATCATAGC AATTCTCATC GGCCTGGTTC TTGGAACTTT GGTGGTGGGA 
ACTGTGGTCA TTTTTCTGGT GTGGAAGAAA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

H2-M10.5 ( XM_030249732.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030105592.1 Mus musculus histocompatibility 2, M region locus 10.5 (H2-M10.5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu87173
Clone ID Related Accession (Same CDS sequence)	XM_030249732.1
Accession Version	XM_030249732.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	histocompatibility 2, M region locus 10.5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGAACC CTGGATGCTG CACACTCCTC CTCCTCTTGG TGGCCATGGA CCTGATCCAG 
TATTGTGCAG TTTTGCTACC TCGGGTTGCA TGGATGGAGC AGGTGCCAAT GACATATTGG 
ACCAGTGAGA CAGCAAGCGT TGCGGAATTG TCACAGCTAG ACAGACGAAT TCTTCACTTC 
ATGGTGAACA AAAATGAACA AAGAATGGAC GATTATCACA CCCTGCAGGA AGTGTATGGC 
TGCAATGTGG CTAATGATGG GAGCTTCCTC GGCGGTCACT TCCGGCTCAC CTACTATGGC 
TATGATGACT TATACCTGAA TGAGAACCTG AGCTCCTGGA TTGCACATGG AAACGCAGCT 
GAATATGTGA AGAGCAGGTG GGACGGTGAA GGTGATGCAG AAAGGTGGAA GACTTACCTG 
CAAGGAGTGT GCGTGGAAAG GCTTCTTAGA TACATGGTCC TTGGAAAGGA AGCATTGCTG 
CGCTCCGATG CCCCCCGAAC ACATGTGACC CACCATGTAA GACCTGAAGG GAATGTCACC 
CTGAGGTGCT GGGCCCTGGG CTTCTACCCA GCTGACATAA CCATGACTTG GAAGAGGGAT 
GGGAACAACC ACACCCAAGA CATGGAGCTG CCAGACACCA GGCCTGCAGG GGATGGAACC 
TTCCAGAAGT GGGCAGCTGT GGTGGTTCCT TCTGGAGAAG AGCTGAGATA CACATGTCAT 
GTGCACCATA AAGGGTTACC TGAGCCTCTC AAGCTGAAAT GGGAGCCTCC ACACACCATC 
CCCATCATAG CAATTCTCAT CGGCCTGGTT CTTGGAACTT TGGTGGTGGG AACTGTGGTC 
ATTTTTCTGG TGTGGAAGAA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030105592.1
CDS	1..864
Translation	MRNPGCCTLLLLLVAMDLIQYCAVLLPRVAWMEQVPMTYWTSETASVAELSQLDRRILHFMVNKNEQRMDDYHTLQEVYGCNVANDGSFLGGHFRLTYYGYDDLYLNENLSSWIAHGNAAEYVKSRWDGEGDAERWKTYLQGVCVERLLRYMVLGKEALLRSDAPRTHVTHHVRPEGNVTLRCWALGFYPADITMTWKRDGNNHTQDMELPDTRPAGDGTFQKWAAVVVPSGEELRYTCHVHHKGLPEPLKLKWEPPHTIPIIAILIGLVLGTLVVGTVVIFLVWKK

Target ORF information:

RefSeq Version	XM_030249732.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus histocompatibility 2, M region locus 10.5 (H2-M10.5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030249732.1

ORF Insert Sequence:

ATGAGGAACC CTGGATGCTG CACACTCCTC CTCCTCTTGG TGGCCATGGA CCTGATCCAG 
TATTGTGCAG TTTTGCTACC TCGGGTTGCA TGGATGGAGC AGGTGCCAAT GACATATTGG 
ACCAGTGAGA CAGCAAGCGT TGCGGAATTG TCACAGCTAG ACAGACGAAT TCTTCACTTC 
ATGGTGAACA AAAATGAACA AAGAATGGAC GATTATCACA CCCTGCAGGA AGTGTATGGC 
TGCAATGTGG CTAATGATGG GAGCTTCCTC GGCGGTCACT TCCGGCTCAC CTACTATGGC 
TATGATGACT TATACCTGAA TGAGAACCTG AGCTCCTGGA TTGCACATGG AAACGCAGCT 
GAATATGTGA AGAGCAGGTG GGACGGTGAA GGTGATGCAG AAAGGTGGAA GACTTACCTG 
CAAGGAGTGT GCGTGGAAAG GCTTCTTAGA TACATGGTCC TTGGAAAGGA AGCATTGCTG 
CGCTCCGATG CCCCCCGAAC ACATGTGACC CACCATGTAA GACCTGAAGG GAATGTCACC 
CTGAGGTGCT GGGCCCTGGG CTTCTACCCA GCTGACATAA CCATGACTTG GAAGAGGGAT 
GGGAACAACC ACACCCAAGA CATGGAGCTG CCAGACACCA GGCCTGCAGG GGATGGAACC 
TTCCAGAAGT GGGCAGCTGT GGTGGTTCCT TCTGGAGAAG AGCTGAGATA CACATGTCAT 
GTGCACCATA AAGGGTTACC TGAGCCTCTC AAGCTGAAAT GGGAGCCTCC ACACACCATC 
CCCATCATAG CAATTCTCAT CGGCCTGGTT CTTGGAACTT TGGTGGTGGG AACTGTGGTC 
ATTTTTCTGG TGTGGAAGAA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional expression of murine V2R pheromone receptors involves selective association with the M10 and M1 families of MHC class Ib molecules.
Cell112(5)607-18(2003 Mar)
Loconto J,Papes F,Chang E,Stowers L,Jones EP,Takada T,Kum?novics A,Fischer Lindahl K,Dulac C

Combinatorial coexpression of neural and immune multigene families in mouse vomeronasal sensory neurons.
Current biology : CB13(5)394-400(2003 Mar)
Ishii T,Hirota J,Mombaerts P

Characterization of two class I genes from the H2-M region: evidence for a new subfamily.
Immunogenetics47(3)264-71(1998)
Arepalli SR,Jones EP,Howcroft TK,Carlo I,Wang C,Lindahl KF,Singer DS,Rudikoff S