Ctr9 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ctr9
Entrez Gene ID	22083
Full Name	CTR9 homolog, Paf1/RNA polymerase II complex component
Synonyms	AA409336,Sh2bp1,Tsbp,Tsp,mKIAA0155
General protein information	Preferred Names CTR9 homolog, Paf1/RNA polymerase II complex component Names RNA polymerase-associated protein CTR9 homolog Ctr9, Paf1/RNA polymerase II complex component, homolog SH2 domain binding protein 1 (tetratricopeptide repeat containing) SH2 domain-binding protein 1 TPR-containing, SH2-binding phosphoprotein of 150 kDa p150TSP tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7 E3\|7 57.98 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_009431.2	NP_033457.2	RNA polymerase-associated protein CTR9 homolog

Pathways from BioSystems

Homologies

Caenorhabditis elegans (roundworm)	B0464.2	NP_001254998.1
Canis lupus familiaris (dog)	CTR9	XP_003639833.1
Drosophila melanogaster (fruit fly)	CG2469	NP_788448.1
Xenopus tropicalis (tropical clawed frog)	ctr9	NP_001005076.1
Bos taurus (cattle)	CTR9	NP_001192326.1
Gallus gallus (chicken)	CTR9	XP_420968.3
Danio rerio (zebrafish)	ctr9	NP_001077052.1
Rattus norvegicus (Norway rat)	Ctr9	NP_001094131.1
Oryza sativa (rice)	Os07g0476200	NP_001059625.1
Homo sapiens (human)	CTR9	NP_055448.1
Pan troglodytes (chimpanzee)	CTR9	XP_521841.3
	CTR9	XP_001094093.2
Mus musculus (house mouse)	Ctr9	NP_033457.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001559	XP_321554.1
Arabidopsis thaliana (thale cress)	ELF8	NP_178674.6

Gene Ontology
Bibliography

Related articles in PubMed

SET domain-containing protein 5 is required for expression of primordial germ cell specification-associated genes in murine embryonic stem cells.
Yu SE, Kim MS, Park SH, Yoo BC, Kim KH, Jang YK
Cell biochemistry and function35(5)247-253(2017 Jul)

Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation.
Osipovich AB, Gangula R, Vianna PG, Magnuson MA
Development (Cambridge, England)143(24)4595-4607(2016 12)

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.
Strikoudis A, Lazaris C, Trimarchi T, Galvao Neto AL, Yang Y, Ntziachristos P, Rothbart S, Buckley S, Dolgalev I, Stadtfeld M, Strahl BD, Dynlacht BD, Tsirigos A, Aifantis I
Nature cell biology18(11)1127-1138(2016 Nov)

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.
Cui W, Dai X, Marcho C, Han Z, Zhang K, Tremblay KD, Mager J
Scientific reports637396(2016 Nov)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

our data suggest that Setd5 is required for maintaining PGC-associated genes and Setd5-associated protein complexes containing Tbl1xr1 and Ctr9, which in turn are likely involved in regulating germ cell-related genes in mESCs
Title: SET domain-containing protein 5 is required for expression of primordial germ cell specification-associated genes in murine embryonic stem cells.

these data propose a novel feed-forward loop of IL-17 transcriptional regulatory circuit, via IL-6-mediated repression of CTR9 which is a transcriptional repressor of IL-17.
Title: Transcriptional regulator CTR9 inhibits Th17 differentiation via repression of IL-17 expression.

MLL interacts directly with the polymerase associated factor complex (PAFc) via Paf1 and CTR9. PAFc augments MLL and MLL-AF9 mediated transcriptional activation of Hoxa9 and their interaction is essential for leukemogenesis.
Title: The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis.

CTR9 participates in the transcription of IL-6-responsive genes through the regulation of DNA association of STAT3 and modification of histone methylation
Title: hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactions.

The following Ctr9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ctr9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18076	NM_009431.2 Latest version!	Mus musculus CTR9 homolog, Paf1/RNA polymerase II complex component (Ctr9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ctr9 ( NM_009431.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033457.2 Mus musculus CTR9 homolog, Paf1/RNA polymerase II complex component (Ctr9), mRNA.

Price & Availability↑

CloneID	OMu18076
Clone ID Related Accession (Same CDS sequence)	NM_009431.2
Accession Version	NM_009431.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3522bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	RNA polymerase-associated protein CTR9 homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY012072.1, BC024749.1, L49502.1 and AI841408.1. On Jul 27, 2007 this sequence version replaced NM_009431.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660813.76864.1, L49502.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGCGGG GCTCCATCGA GATTCCCCTC CGGGATACTG ACGAGGTCAT TGAACTTGAC 
TTCGATCAGT TACCGGAGGG AGACGAAGTC ATCAGCATTC TGAAGCAGGA GCACACACAA 
CTGCACATAT GGATTGCCTT GGCGCTGGAA TACTACAAGC AAGGGAAAAC AGAAGAGTTT 
GTGAAGCTGC TGGAGGCAGC ACGGATAGAT GGCAATTTGG ACTATCGAGA TCACGAGAAA 
GACCAGATGA CTTGCTTGGA TACATTGGCA GCCTACTATG TACAACAGGC TCGGAAAGAA 
AAGAACAAGG ACAATAAGAA GGACCTTATT ACGCAGGCAA CTTTGTTATA TACAATGGCT 
GATAAAATTA TTATGTATGA TCAGAACCAT TTGTTGGGAA GAGCCTGCTT CTGTCTGCTC 
GAGGGCGACA AAATGGACCA AGCTGACGCA CAGTTTCACT TTGTACTTAA CCAGTCTCCA 
AACAATATTC CAGCCCTTCT TGGGAAAGCT TGTATTTCAT TCAACAAGAA GGATTACAGA 
GGAGCTCTGG CTTACTATAA AAAAGCATTG CGCACTAACC CGGGATGTCC AGCTGAAGTT 
CGTTTAGGAA TGGGCCATTG CTTTGTCAAA CTTAACAAAC TGGAAAAAGC TCGACTGGCA 
TTCAGCAGAG CCCTGGAACT CAACTCGAAG TGTGTGGGAG CACTGGTTGG ACTGGCTGTT 
CTAGAACTCA ACAATAAAGA GGCTGATTCC ATCAAAAATG GCGTGCAGCT TCTTTCCAGA 
GCCTATACTA TTGATCCTAG CAACCCGATG GTACTGAACC ATTTGGCAAA CCACTTTTTC 
TTCAAGAAGG ATTATAGTAA AGTGCAGCAC CTGGCTCTCC ACGCATTCCA CAACACCGAG 
GTGGAGGCTA TGCAAGCAGA AAGCTGTTAC CAGCTGGCTC GGTCCTTCCA TGTTCAGGAA 
GATTATGACC AAGCCTTTCA GTACTACTAT CAAGCCACAC AGTTTGCTTC ATCTTCCTTT 
GTCCTACCAT TTTTTGGTTT GGGACAAATG TATATTTATC GAGGTGACAA AGAGAATGCA 
TCTCAGTGCT TTGAGAAAGT TTTGAAAGCT TATCCGAACA ATTATGAAAC TATGAAAATT 
CTTGGCTCTC TCTATGCTGC TTCAGAAGAT CAGGAGAAAC GAGACATAGC CAAGGGCCAT 
TTGAAGAAGG TCACAGAACA GTATCCTGAT GACGTGGAAG CTTGGATTGA GTTGGCCCAG 
ATCTTAGAAC AGACTGACAT ACAGGGTGCC CTTTCAGCTT ATGGAACAGC CACACGCATC 
CTGCAGGAGA AAGTGCAGGC CGATGTCCCT CCCGAGATTT TGAATAATGT TGGGGCCCTC 
CATTTTAGAC TCGGAAACCT GGGGGAAGCA AAGAAATACT TCCTGGCCTC ACTGGACCGC 
GCAAAGGCAG AGGCCGAGCA TGATGAACAC TACTACAATG CCATCTCTGT CACCACATCC 
TACAATTTAG CCAGGCTCTA TGAGGCCATG TGTGAATTTC ACGAAGCAGA GAAACTGTAC 
AAAAACATTT TACGAGAGCA TCCTAACTAC GTTGATTGCT ATCTACGCCT AGGAGCCATG 
GCCAGAGATA AAGGAAACTT CTATGAAGCT TCAGACTGGT TTAAGGAAGC CCTTCAGATC 
AATCAGGATC ATCCGGATGC CTGGTCTTTG ATTGGTAACC TCCATCTGGC AAAACAAGAA 
TGGGGCCCAG GTCAGAAGAA GTTTGAGAGG ATATTAAAAC AGCCAGCCAC ACAGAGTGAC 
ACCTACTCTA TGCTGGCCCT TGGCAATGTG TGGCTCCAGA CTTTGCATCA GCCAACCCGA 
GACCGAGAAA AGGAAAAGCG CCATCAAGAC CGTGCCCTGG CCATCTACAA ACAAGTCCTC 
AGAAATGATG CCAAGAACCT GTATGCTGCC AATGGCATAG GAGCTGTCTT GGCCCACAAA 
GGATACTTCC GTGAAGCTCG TGATGTTTTC GCCCAAGTGA GAGAAGCAAC AGCAGATATC 
AGTGATGTGT GGTTGAACCT AGCACACATC TACGTGGAGC AGAAGCAGTA TATCAGCGCC 
GTTCAGATGT ATGAGAACTG CCTCAGAAAG TTCTATAAGC ACCAAAACAC TGAGGTTGTG 
CTCTACCTGG CCCGCGCCCT CTTCAAGTGC GGCAAGCTGC AGGAGTGCAA GCAGACTCTG 
CTGAAGGCCA GACACGTGGC ACCCAGTGAC ACAGTTCTGA TGTTTAATGT GGCCTTGGTC 
TTGCAAAGAT TAGCTACCTC TGTCCTGAAA GATGAAAAAA GTAATCTGAA GGAAGTCCTT 
AATGCTGTGA AAGAGCTGGA GCTCGCACAC AGGTACTTCA GTTACTTGAG CAAAGTTGGA 
GATAAAATGA GATTTGATTT GGCCCTTGCT GCCTCTGAAG CCAGGCAGTG CTCTGACTTA 
CTGAGCCAGG CCCAGTACCA TGTGGCCCGG GCACGCAAGC AGGATGAGGA AGAACGGGAG 
CTGCGGGCCA AGCAGGAGCA GGAAAAGGAG CTCTTAAGAC AGAAGCTTCT CAAAGAGCAG 
GAAGAGAAAC GTCTCAGAGA AAAGGAAGAA CAAAAGAAAC TTTTGGAACA GCGTGCCCAG 
TATGTGGAGA AGACCAAAAA TATCCTTATG TTCACTGGCG AGACTGAAGC AACAAAGGAG 
AAGAAAAGAG GTGGAGGTGG AGGGCGGCGT TCCAAGAAAG GAGGCGAGTT TGATGAATTT 
GTCAACGATG ACACCGACGA TGACCTCCCT GTATCCAAAA AGAAGAAGAG AAGGAAGGGC 
AGTGGCAGTG AACAGGAAGG CGAAGAAGAG GAAGGTGGAG AGAGGAAGAA GAAGAGGAGG 
AGAAGACCTC CAAAGGGAGA AGAGGGATCT GAGGAGGAGG AGACAGAAAA TGGCCCCAAA 
CCAAAGAAGC GCCGCCCACC GAGAGCAGAG AAAAAGAAGG CTCCCAAGCC AGAACGCCTG 
CCTCCTTCAA TGAAGGGAAA AATAAAATCC AAAGCCATTA TATCATCAAG TGATGATTCT 
TCAGATGAGG ATAAACTGAA AATTGCTGAT GAAGGACATC CCAGGAATAG CAACAGCGAT 
TCTGATGACG ACGAGAGGCC CAACAGACGC GCCTCATCTG AGAGCGACTC AGATGACAAC 
CAGAACAAGT CTGGCAGCGA GGCAGGCAGC CCTCGGAGGT CGGGTAGACA GGAGTCGGAT 
GAGGATTCCG ACAGTGACCA GCCGTCCAGA AAGAGAAGGC GCTCCGGCTC TGAGCAGTCG 
GACAATGAGT CTGTGCAGTC AGGGAGAAGC CCCTCCGGAG CTTCTGAGAA CGAGAACGAT 
TCTCGCCCGG CTTCTCCAAG TGCAGAATCG GACCACGAAT CAGAGCAGGG CTCTGACAAC 
GAGGGCTCTG GCCAAGGCTC TGGAAATGAA TCAGAACCAG AGGGCTCAAA CAACGAGGCC 
TCAGACCGAG GCTCAGAACA TGGGTCAGAT GATAGCGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033457.2
CDS	187..3708
Translation	MSRGSIEIPLRDTDEVIELDFDQLPEGDEVISILKQEHTQLHIWIALALEYYKQGKTEEFVKLLEAARIDGNLDYRDHEKDQMTCLDTLAAYYVQQARKEKNKDNKKDLITQATLLYTMADKIIMYDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAFHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPATQSDTYSMLALGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVVLYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVLNAVKELELAHRYFSYLSKVGDKMRFDLALAASEARQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPVSKKKKRRKGSGSEQEGEEEEGGERKKKRRRRPPKGEEGSEEEETENGPKPKKRRPPRAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSDSDDDERPNRRASSESDSDDNQNKSGSEAGSPRRSGRQESDEDSDSDQPSRKRRRSGSEQSDNESVQSGRSPSGASENENDSRPASPSAESDHESEQGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD

Target ORF information:

RefSeq Version	NM_009431.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus CTR9 homolog, Paf1/RNA polymerase II complex component (Ctr9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009431.2

ORF Insert Sequence:

ATGTCGCGGG GCTCCATCGA GATTCCCCTC CGGGATACTG ACGAGGTCAT TGAACTTGAC 
TTCGATCAGT TACCGGAGGG AGACGAAGTC ATCAGCATTC TGAAGCAGGA GCACACACAA 
CTGCACATAT GGATTGCCTT GGCGCTGGAA TACTACAAGC AAGGGAAAAC AGAAGAGTTT 
GTGAAGCTGC TGGAGGCAGC ACGGATAGAT GGCAATTTGG ACTATCGAGA TCACGAGAAA 
GACCAGATGA CTTGCTTGGA TACATTGGCA GCCTACTATG TACAACAGGC TCGGAAAGAA 
AAGAACAAGG ACAATAAGAA GGACCTTATT ACGCAGGCAA CTTTGTTATA TACAATGGCT 
GATAAAATTA TTATGTATGA TCAGAACCAT TTGTTGGGAA GAGCCTGCTT CTGTCTGCTC 
GAGGGCGACA AAATGGACCA AGCTGACGCA CAGTTTCACT TTGTACTTAA CCAGTCTCCA 
AACAATATTC CAGCCCTTCT TGGGAAAGCT TGTATTTCAT TCAACAAGAA GGATTACAGA 
GGAGCTCTGG CTTACTATAA AAAAGCATTG CGCACTAACC CGGGATGTCC AGCTGAAGTT 
CGTTTAGGAA TGGGCCATTG CTTTGTCAAA CTTAACAAAC TGGAAAAAGC TCGACTGGCA 
TTCAGCAGAG CCCTGGAACT CAACTCGAAG TGTGTGGGAG CACTGGTTGG ACTGGCTGTT 
CTAGAACTCA ACAATAAAGA GGCTGATTCC ATCAAAAATG GCGTGCAGCT TCTTTCCAGA 
GCCTATACTA TTGATCCTAG CAACCCGATG GTACTGAACC ATTTGGCAAA CCACTTTTTC 
TTCAAGAAGG ATTATAGTAA AGTGCAGCAC CTGGCTCTCC ACGCATTCCA CAACACCGAG 
GTGGAGGCTA TGCAAGCAGA AAGCTGTTAC CAGCTGGCTC GGTCCTTCCA TGTTCAGGAA 
GATTATGACC AAGCCTTTCA GTACTACTAT CAAGCCACAC AGTTTGCTTC ATCTTCCTTT 
GTCCTACCAT TTTTTGGTTT GGGACAAATG TATATTTATC GAGGTGACAA AGAGAATGCA 
TCTCAGTGCT TTGAGAAAGT TTTGAAAGCT TATCCGAACA ATTATGAAAC TATGAAAATT 
CTTGGCTCTC TCTATGCTGC TTCAGAAGAT CAGGAGAAAC GAGACATAGC CAAGGGCCAT 
TTGAAGAAGG TCACAGAACA GTATCCTGAT GACGTGGAAG CTTGGATTGA GTTGGCCCAG 
ATCTTAGAAC AGACTGACAT ACAGGGTGCC CTTTCAGCTT ATGGAACAGC CACACGCATC 
CTGCAGGAGA AAGTGCAGGC CGATGTCCCT CCCGAGATTT TGAATAATGT TGGGGCCCTC 
CATTTTAGAC TCGGAAACCT GGGGGAAGCA AAGAAATACT TCCTGGCCTC ACTGGACCGC 
GCAAAGGCAG AGGCCGAGCA TGATGAACAC TACTACAATG CCATCTCTGT CACCACATCC 
TACAATTTAG CCAGGCTCTA TGAGGCCATG TGTGAATTTC ACGAAGCAGA GAAACTGTAC 
AAAAACATTT TACGAGAGCA TCCTAACTAC GTTGATTGCT ATCTACGCCT AGGAGCCATG 
GCCAGAGATA AAGGAAACTT CTATGAAGCT TCAGACTGGT TTAAGGAAGC CCTTCAGATC 
AATCAGGATC ATCCGGATGC CTGGTCTTTG ATTGGTAACC TCCATCTGGC AAAACAAGAA 
TGGGGCCCAG GTCAGAAGAA GTTTGAGAGG ATATTAAAAC AGCCAGCCAC ACAGAGTGAC 
ACCTACTCTA TGCTGGCCCT TGGCAATGTG TGGCTCCAGA CTTTGCATCA GCCAACCCGA 
GACCGAGAAA AGGAAAAGCG CCATCAAGAC CGTGCCCTGG CCATCTACAA ACAAGTCCTC 
AGAAATGATG CCAAGAACCT GTATGCTGCC AATGGCATAG GAGCTGTCTT GGCCCACAAA 
GGATACTTCC GTGAAGCTCG TGATGTTTTC GCCCAAGTGA GAGAAGCAAC AGCAGATATC 
AGTGATGTGT GGTTGAACCT AGCACACATC TACGTGGAGC AGAAGCAGTA TATCAGCGCC 
GTTCAGATGT ATGAGAACTG CCTCAGAAAG TTCTATAAGC ACCAAAACAC TGAGGTTGTG 
CTCTACCTGG CCCGCGCCCT CTTCAAGTGC GGCAAGCTGC AGGAGTGCAA GCAGACTCTG 
CTGAAGGCCA GACACGTGGC ACCCAGTGAC ACAGTTCTGA TGTTTAATGT GGCCTTGGTC 
TTGCAAAGAT TAGCTACCTC TGTCCTGAAA GATGAAAAAA GTAATCTGAA GGAAGTCCTT 
AATGCTGTGA AAGAGCTGGA GCTCGCACAC AGGTACTTCA GTTACTTGAG CAAAGTTGGA 
GATAAAATGA GATTTGATTT GGCCCTTGCT GCCTCTGAAG CCAGGCAGTG CTCTGACTTA 
CTGAGCCAGG CCCAGTACCA TGTGGCCCGG GCACGCAAGC AGGATGAGGA AGAACGGGAG 
CTGCGGGCCA AGCAGGAGCA GGAAAAGGAG CTCTTAAGAC AGAAGCTTCT CAAAGAGCAG 
GAAGAGAAAC GTCTCAGAGA AAAGGAAGAA CAAAAGAAAC TTTTGGAACA GCGTGCCCAG 
TATGTGGAGA AGACCAAAAA TATCCTTATG TTCACTGGCG AGACTGAAGC AACAAAGGAG 
AAGAAAAGAG GTGGAGGTGG AGGGCGGCGT TCCAAGAAAG GAGGCGAGTT TGATGAATTT 
GTCAACGATG ACACCGACGA TGACCTCCCT GTATCCAAAA AGAAGAAGAG AAGGAAGGGC 
AGTGGCAGTG AACAGGAAGG CGAAGAAGAG GAAGGTGGAG AGAGGAAGAA GAAGAGGAGG 
AGAAGACCTC CAAAGGGAGA AGAGGGATCT GAGGAGGAGG AGACAGAAAA TGGCCCCAAA 
CCAAAGAAGC GCCGCCCACC GAGAGCAGAG AAAAAGAAGG CTCCCAAGCC AGAACGCCTG 
CCTCCTTCAA TGAAGGGAAA AATAAAATCC AAAGCCATTA TATCATCAAG TGATGATTCT 
TCAGATGAGG ATAAACTGAA AATTGCTGAT GAAGGACATC CCAGGAATAG CAACAGCGAT 
TCTGATGACG ACGAGAGGCC CAACAGACGC GCCTCATCTG AGAGCGACTC AGATGACAAC 
CAGAACAAGT CTGGCAGCGA GGCAGGCAGC CCTCGGAGGT CGGGTAGACA GGAGTCGGAT 
GAGGATTCCG ACAGTGACCA GCCGTCCAGA AAGAGAAGGC GCTCCGGCTC TGAGCAGTCG 
GACAATGAGT CTGTGCAGTC AGGGAGAAGC CCCTCCGGAG CTTCTGAGAA CGAGAACGAT 
TCTCGCCCGG CTTCTCCAAG TGCAGAATCG GACCACGAAT CAGAGCAGGG CTCTGACAAC 
GAGGGCTCTG GCCAAGGCTC TGGAAATGAA TCAGAACCAG AGGGCTCAAA CAACGAGGCC 
TCAGACCGAG GCTCAGAACA TGGGTCAGAT GATAGCGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SET domain-containing protein 5 is required for expression of primordial germ cell specification-associated genes in murine embryonic stem cells.
Cell biochemistry and function35(5)247-253(2017 Jul)
Yu SE,Kim MS,Park SH,Yoo BC,Kim KH,Jang YK

Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation.
Development (Cambridge, England)143(24)4595-4607(2016 12)
Osipovich AB,Gangula R,Vianna PG,Magnuson MA

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.
Nature cell biology18(11)1127-1138(2016 Nov)
Strikoudis A,Lazaris C,Trimarchi T,Galvao Neto AL,Yang Y,Ntziachristos P,Rothbart S,Buckley S,Dolgalev I,Stadtfeld M,Strahl BD,Dynlacht BD,Tsirigos A,Aifantis I

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.
Scientific reports637396(2016 Nov)
Cui W,Dai X,Marcho C,Han Z,Zhang K,Tremblay KD,Mager J

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

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Ctr9 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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