Trf cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Trf
Entrez Gene ID	22041
Full Name	transferrin
Synonyms	AI266983,Cd176,HP,Tf,Tfn,hpx
General protein information	Preferred Names transferrin Names serotransferrin beta-1 metal-binding globulin hypotransferrinemia with hemochromatosis siderophilin
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9 F1\|9 55.03 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_133977.2	NP_598738.1	serotransferrin precursor

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	tf	NP_001027487.1
Bos taurus (cattle)	TF	NP_803450.2
Rattus norvegicus (Norway rat)	Tf	NP_001013128.1
Mus musculus (house mouse)	Trf	NP_598738.1
Homo sapiens (human)	TF	NP_001054.1
Canis lupus familiaris (dog)	TF	XP_534268.3
Gallus gallus (chicken)	TF	NP_990635.1
Pan troglodytes (chimpanzee)	TF	NP_001138307.1
Danio rerio (zebrafish)	tfa	NP_001015057.1

Gene Ontology
Bibliography

Related articles in PubMed

Energetics of ligand-receptor binding affinity on endothelial cells: An in vitro model.
Fotticchia I, Guarnieri D, Fotticchia T, Falanga AP, Vecchione R, Giancola C, Netti PA
Colloids and surfaces. B, Biointerfaces144250-256(2016 Aug)

Identification of multiple transferrin species in the spleen and serum from mice with collagen-induced arthritis which may reflect changes in transferrin glycosylation associated with disease activity: The role of CD38.
Rosal-Vela A, Barroso A, Gim?nez E, Garc?a-Rodr?guez S, Longobardo V, Postigo J, Iglesias M, Lario A, Merino J, Merino R, Zubiaur M, Sanz-Nebot V, Sancho J
Journal of proteomics134127-137(2016 Feb)

Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity.
Liu K, Lei R, Li Q, Wang XX, Wu Q, An P, Zhang J, Zhu M, Xu Z, Hong Y, Wang F, Shen Y, Li H, Li H
Scientific reports621019(2016 Feb)

Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production.
Lun MP, Johnson MB, Broadbelt KG, Watanabe M, Kang YJ, Chau KF, Springel MW, Malesz A, Sousa AM, Pletikos M, Adelita T, Adelita T, Calicchio ML, Zhang Y, Holtzman MJ, Lidov HG, Sestan N, Steen H, Monuki ES, Lehtinen MK
The Journal of neuroscience : the official journal of the Society for Neuroscience35(12)4903-16(2015 Mar)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the value of transferrin receptors (TfRs)/cell reveals a 100-fold increase in the number of TfRs per bEnd3 cells compared to human umbilical vein cells.
Title: Energetics of ligand-receptor binding affinity on endothelial cells: An in vitro model.

Identification of multiple transferrin species in the spleen and serum from mice with collagen-induced arthritis which may reflect changes in transferrin glycosylation associated with disease activity: The role of CD38.
Title: Identification of multiple transferrin species in the spleen and serum from mice with collagen-induced arthritis which may reflect changes in transferrin glycosylation associated with disease activity: The role of CD38.

Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor.
Title: Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor.

Together, these data indicate that Lcn2, in combination with transferrin, confines Klebsiella pneumoniae to the airways and prevents invasion into tissue containing the pulmonary vasculature.
Title: Interaction of lipocalin 2, transferrin, and siderophores determines the replicative niche of Klebsiella pneumoniae during pneumonia.

These results indicate that CALM is required for erythroid maturation and transferrin internalization in mice.
Title: The clathrin assembly protein PICALM is required for erythroid maturation and transferrin internalization in mice.

The following Trf gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Trf cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu16528	NM_133977.2 Latest version!	Mus musculus transferrin (Trf), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$412.30 $589.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Trf ( NM_133977.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598738.1 Mus musculus transferrin (Trf), mRNA.

Price & Availability↑

CloneID	OMu16528
Clone ID Related Accession (Same CDS sequence)	NM_133977.2
Accession Version	NM_133977.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2094bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	serotransferrin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC156633.2. On Nov 17, 2006 this sequence version replaced NM_133977.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC012313.1, AK150782.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGAGGCTCA CCGTGGGTGC CCTGCTGGCC TGCGCTGCCC TGGGGCTGTG TCTGGCTGTC 
CCTGACAAAA CGGTCAAATG GTGCGCAGTG TCAGAGCACG AGAATACCAA GTGCATCAGC 
TTCCGTGACC ACATGAAGAC CGTCCTTCCG CCTGATGGCC CCCGGCTTGC CTGTGTGAAG 
AAAACCTCCT ATCCGGATTG CATCAAGGCC ATTTCTGCAA GTGAAGCCGA TGCTATGACC 
TTGGATGGGG GTTGGGTGTA CGATGCCGGC CTGACTCCGA ACAACCTGAA GCCCGTGGCG 
GCGGAGTTTT ATGGATCAGT GGAACATCCA CAGACCTACT ACTACGCTGT GGCTGTGGTA 
AAGAAGGGAA CAGACTTCCA GCTGAACCAG CTCGAAGGCA AGAAGTCCTG CCACACAGGC 
CTGGGAAGGT CTGCAGGCTG GGTCATCCCC ATTGGCTTGC TCTTCTGTAA GCTGTCGGAG 
CCCCGCAGTC CTCTTGAGAA AGCTGTGTCC AGTTTCTTCT CGGGCAGTTG TGTCCCCTGT 
GCAGATCCAG TGGCCTTCCC CAAACTGTGT CAACTGTGCC CAGGCTGTGG CTGCTCCTCC 
ACTCAACCAT TCTTTGGCTA CGTAGGCGCA TTCAAGTGTC TGAAAGATGG CGGTGGGGAT 
GTGGCCTTTG TCAAGCACAC AACCATATTT GAGGTCTTGC CGGAGAAGGC TGACAGGGAC 
CAATATGAAC TGCTCTGCCT TGACAATACC CGCAAGCCAG TGGATCAGTA TGAGGATTGC 
TACCTGGCTC GGATCCCTTC TCATGCTGTT GTGGCTCGAA AAAACAATGG CAAGGAAGAC 
TTGATCTGGG AGATTCTCAA AGTGGCACAG GAACACTTTG GCAAAGGCAA ATCAAAAGAC 
TTCCAACTGT TCAGCTCTCC TCTTGGGAAA GACCTGCTGT TTAAAGATTC TGCCTTTGGG 
CTGTTAAGGG TCCCCCCAAG GATGGACTAC AGGCTGTACC TTGGCCATAA CTATGTCACT 
GCCATTCGGA ATCAGCAGGA AGGCGTGTGC CCGGAGGGCT CGATCGACAA CTCGCCAGTG 
AAGTGGTGTG CACTGAGTCA CCTGGAGAGA ACCAAGTGTG ACGAGTGGAG CATCATCAGT 
GAGGGAAAGA TAGAGTGTGA GTCAGCAGAG ACCACTGAGG ACTGCATTGA AAAGATTGTG 
AACGGAGAAG CGGACGCCAT GACTTTGGAT GGAGGACATG CCTACATTGC AGGCCAGTGT 
GGTCTAGTGC CTGTCATGGC AGAGTACTAC GAGAGCTCTA ATTGTGCCAT CCCATCACAA 
CAAGGTATCT TTCCTAAAGG GTATTATGCC GTGGCTGTGG TGAAGGCATC GGACACTAGC 
ATCACCTGGA ACAACCTGAA AGGCAAGAAG TCCTGCCACA CTGGGGTAGA CAGAACCGCT 
GGTTGGAACA TCCCTATGGG CATGCTGTAC AACAGGATCA ACCACTGCAA ATTCGATGAA 
TTTTTCAGTC AAGGCTGCGC TCCCGGGTAT GAGAAGAATT CCACCCTCTG TGACCTGTGT 
ATTGGCCCAC TCAAATGTGC TCCGAACAAC AAAGAGGAAT ATAATGGTTA CACAGGGGCT 
TTCAGGTGTC TCGTTGAGAA AGGAGATGTA GCCTTTGTGA AACACCAGAC TGTCCTGGAT 
AACACCGAAG GAAAGAACCC TGCCGAATGG GCTAAGAATC TGAAGCAGGA AGACTTCGAG 
TTGCTCTGCC CTGATGGCAC CAGGAAGCCT GTGAAAGATT TTGCCAGCTG CCACCTGGCC 
CAAGCTCCAA ACCATGTTGT GGTCTCACGA AAAGAGAAGG CAGCCCGGGT TAAGGCTGTA 
CTGACTAGCC AGGAGACTTT ATTTGGGGGA AGTGACTGCA CCGGCAATTT CTGTTTGTTC 
AAGTCCACCA CCAAGGACCT TCTGTTCAGG GATGACACCA AATGTTTCGT TAAACTTCCA 
GAGGGTACCA CACCTGAAAA ATACTTAGGA GCGGAGTACA TGCAATCTGT CGGTAACATG 
AGGAAGTGCT CAACCTCACG ACTCCTGGAA GCCTGCACTT TCCACAAACA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598738.1
CDS	71..2164
Translation	MRLTVGALLACAALGLCLAVPDKTVKWCAVSEHENTKCISFRDHMKTVLPPDGPRLACVKKTSYPDCIKAISASEADAMTLDGGWVYDAGLTPNNLKPVAAEFYGSVEHPQTYYYAVAVVKKGTDFQLNQLEGKKSCHTGLGRSAGWVIPIGLLFCKLSEPRSPLEKAVSSFFSGSCVPCADPVAFPKLCQLCPGCGCSSTQPFFGYVGAFKCLKDGGGDVAFVKHTTIFEVLPEKADRDQYELLCLDNTRKPVDQYEDCYLARIPSHAVVARKNNGKEDLIWEILKVAQEHFGKGKSKDFQLFSSPLGKDLLFKDSAFGLLRVPPRMDYRLYLGHNYVTAIRNQQEGVCPEGSIDNSPVKWCALSHLERTKCDEWSIISEGKIECESAETTEDCIEKIVNGEADAMTLDGGHAYIAGQCGLVPVMAEYYESSNCAIPSQQGIFPKGYYAVAVVKASDTSITWNNLKGKKSCHTGVDRTAGWNIPMGMLYNRINHCKFDEFFSQGCAPGYEKNSTLCDLCIGPLKCAPNNKEEYNGYTGAFRCLVEKGDVAFVKHQTVLDNTEGKNPAEWAKNLKQEDFELLCPDGTRKPVKDFASCHLAQAPNHVVVSRKEKAARVKAVLTSQETLFGGSDCTGNFCLFKSTTKDLLFRDDTKCFVKLPEGTTPEKYLGAEYMQSVGNMRKCSTSRLLEACTFHKH

Target ORF information:

RefSeq Version	NM_133977.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus transferrin (Trf), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133977.2

ORF Insert Sequence:

ATGAGGCTCA CCGTGGGTGC CCTGCTGGCC TGCGCTGCCC TGGGGCTGTG TCTGGCTGTC 
CCTGACAAAA CGGTCAAATG GTGCGCAGTG TCAGAGCACG AGAATACCAA GTGCATCAGC 
TTCCGTGACC ACATGAAGAC CGTCCTTCCG CCTGATGGCC CCCGGCTTGC CTGTGTGAAG 
AAAACCTCCT ATCCGGATTG CATCAAGGCC ATTTCTGCAA GTGAAGCCGA TGCTATGACC 
TTGGATGGGG GTTGGGTGTA CGATGCCGGC CTGACTCCGA ACAACCTGAA GCCCGTGGCG 
GCGGAGTTTT ATGGATCAGT GGAACATCCA CAGACCTACT ACTACGCTGT GGCTGTGGTA 
AAGAAGGGAA CAGACTTCCA GCTGAACCAG CTCGAAGGCA AGAAGTCCTG CCACACAGGC 
CTGGGAAGGT CTGCAGGCTG GGTCATCCCC ATTGGCTTGC TCTTCTGTAA GCTGTCGGAG 
CCCCGCAGTC CTCTTGAGAA AGCTGTGTCC AGTTTCTTCT CGGGCAGTTG TGTCCCCTGT 
GCAGATCCAG TGGCCTTCCC CAAACTGTGT CAACTGTGCC CAGGCTGTGG CTGCTCCTCC 
ACTCAACCAT TCTTTGGCTA CGTAGGCGCA TTCAAGTGTC TGAAAGATGG CGGTGGGGAT 
GTGGCCTTTG TCAAGCACAC AACCATATTT GAGGTCTTGC CGGAGAAGGC TGACAGGGAC 
CAATATGAAC TGCTCTGCCT TGACAATACC CGCAAGCCAG TGGATCAGTA TGAGGATTGC 
TACCTGGCTC GGATCCCTTC TCATGCTGTT GTGGCTCGAA AAAACAATGG CAAGGAAGAC 
TTGATCTGGG AGATTCTCAA AGTGGCACAG GAACACTTTG GCAAAGGCAA ATCAAAAGAC 
TTCCAACTGT TCAGCTCTCC TCTTGGGAAA GACCTGCTGT TTAAAGATTC TGCCTTTGGG 
CTGTTAAGGG TCCCCCCAAG GATGGACTAC AGGCTGTACC TTGGCCATAA CTATGTCACT 
GCCATTCGGA ATCAGCAGGA AGGCGTGTGC CCGGAGGGCT CGATCGACAA CTCGCCAGTG 
AAGTGGTGTG CACTGAGTCA CCTGGAGAGA ACCAAGTGTG ACGAGTGGAG CATCATCAGT 
GAGGGAAAGA TAGAGTGTGA GTCAGCAGAG ACCACTGAGG ACTGCATTGA AAAGATTGTG 
AACGGAGAAG CGGACGCCAT GACTTTGGAT GGAGGACATG CCTACATTGC AGGCCAGTGT 
GGTCTAGTGC CTGTCATGGC AGAGTACTAC GAGAGCTCTA ATTGTGCCAT CCCATCACAA 
CAAGGTATCT TTCCTAAAGG GTATTATGCC GTGGCTGTGG TGAAGGCATC GGACACTAGC 
ATCACCTGGA ACAACCTGAA AGGCAAGAAG TCCTGCCACA CTGGGGTAGA CAGAACCGCT 
GGTTGGAACA TCCCTATGGG CATGCTGTAC AACAGGATCA ACCACTGCAA ATTCGATGAA 
TTTTTCAGTC AAGGCTGCGC TCCCGGGTAT GAGAAGAATT CCACCCTCTG TGACCTGTGT 
ATTGGCCCAC TCAAATGTGC TCCGAACAAC AAAGAGGAAT ATAATGGTTA CACAGGGGCT 
TTCAGGTGTC TCGTTGAGAA AGGAGATGTA GCCTTTGTGA AACACCAGAC TGTCCTGGAT 
AACACCGAAG GAAAGAACCC TGCCGAATGG GCTAAGAATC TGAAGCAGGA AGACTTCGAG 
TTGCTCTGCC CTGATGGCAC CAGGAAGCCT GTGAAAGATT TTGCCAGCTG CCACCTGGCC 
CAAGCTCCAA ACCATGTTGT GGTCTCACGA AAAGAGAAGG CAGCCCGGGT TAAGGCTGTA 
CTGACTAGCC AGGAGACTTT ATTTGGGGGA AGTGACTGCA CCGGCAATTT CTGTTTGTTC 
AAGTCCACCA CCAAGGACCT TCTGTTCAGG GATGACACCA AATGTTTCGT TAAACTTCCA 
GAGGGTACCA CACCTGAAAA ATACTTAGGA GCGGAGTACA TGCAATCTGT CGGTAACATG 
AGGAAGTGCT CAACCTCACG ACTCCTGGAA GCCTGCACTT TCCACAAACA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Energetics of ligand-receptor binding affinity on endothelial cells: An in vitro model.
Colloids and surfaces. B, Biointerfaces144250-256(2016 Aug)
Fotticchia I,Guarnieri D,Fotticchia T,Falanga AP,Vecchione R,Giancola C,Netti PA

Identification of multiple transferrin species in the spleen and serum from mice with collagen-induced arthritis which may reflect changes in transferrin glycosylation associated with disease activity: The role of CD38.
Journal of proteomics134127-137(2016 Feb)
Rosal-Vela A,Barroso A,Gim?nez E,Garc?a-Rodr?guez S,Longobardo V,Postigo J,Iglesias M,Lario A,Merino J,Merino R,Zubiaur M,Sanz-Nebot V,Sancho J

Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity.
Scientific reports621019(2016 Feb)
Liu K,Lei R,Li Q,Wang XX,Wu Q,An P,Zhang J,Zhu M,Xu Z,Hong Y,Wang F,Shen Y,Li H,Li H

Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production.
The Journal of neuroscience : the official journal of the Society for Neuroscience35(12)4903-16(2015 Mar)
Lun MP,Johnson MB,Broadbelt KG,Watanabe M,Kang YJ,Chau KF,Springel MW,Malesz A,Sousa AM,Pletikos M,Adelita T,Adelita T,Calicchio ML,Zhang Y,Holtzman MJ,Lidov HG,Sestan N,Steen H,Monuki ES,Lehtinen MK

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

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Trf cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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