Tnks cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tnks
Entrez Gene ID	21951
Full Name	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Synonyms	4930554K12Rik,AI662855,ARTD5,C86528,D130072O21Rik,TANK1,mTNKS1
General protein information	Preferred Names tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase Names tankyrase-1 ADP-ribosyltransferase diphtheria toxin-like 5 TRF1-interacting ankyrin-related ADP-ribose polymerase 1 tankyrase I
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8 A4\|8 21.16 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_175091.3	NP_780300.2	poly [ADP-ribose] polymerase tankyrase-1

Pathways from BioSystems

Homologies

Homo sapiens (human)	TNKS	NP_003738.2
Pan troglodytes (chimpanzee)	TNKS	XP_001137443.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001947	XP_321116.5
Bos taurus (cattle)	TNKS	NP_001193089.1
Gallus gallus (chicken)	TNKS	NP_989671.1
Drosophila melanogaster (fruit fly)	tankyrase	NP_001262963.1
Mus musculus (house mouse)	Tnks	NP_780300.2
Rattus norvegicus (Norway rat)	Tnks	NP_001099554.2
Danio rerio (zebrafish)	tnks	XP_687410.3
Canis lupus familiaris (dog)	TNKS	XP_849388.1
	TNKS	XP_001090358.1
Xenopus tropicalis (tropical clawed frog)	tnks	XP_002939302.1

Gene Ontology
Bibliography

Related articles in PubMed

Structural insights into SAM domain-mediated tankyrase oligomerization.
DaRosa PA, Ovchinnikov S, Xu W, Klevit RE
Protein science : a publication of the Protein Society25(9)1744-52(2016 Sep)

Tankyrase inhibition aggravates kidney injury in the absence of CD2AP.
Kuusela S, Wang H, Wasik AA, Suleiman H, Lehtonen S
Cell death & disease7e2302(2016 Jul)

Integrative genomic approach identifies multiple genes involved in cardiac collagen deposition.
Lodder EM, Scicluna BP, Beekman L, Arends D, Moerland PD, Tanck MW, Adriaens ME, Bezzina CR
Circulation. Cardiovascular genetics7(6)790-8(2014 Dec)

mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.
Wentzel C, Sommer JE, Nair R, Stiefvater A, Sibarita JB, Scheiffele P
Neuron78(6)1012-23(2013 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These structural insights will be invaluable for the functional and biophysical characterization of TNKS1/2, including the role of TNKS oligomerization in protein poly(ADP-ribosyl)ation (PARylation) and PARylation-dependent ubiquitylation.
Title: Structural insights into SAM domain-mediated tankyrase oligomerization.

Tank1/Tank2 inhibition aggravates kidney injury in the absence of CD2AP.
Title: Tankyrase inhibition aggravates kidney injury in the absence of CD2AP.

analyses also reveal the structural basis for TNKS substrate recruitment, and shed light on the overall structure of TNKS that should help in developing specific inhibitors of Wnt/beta-catenin signaling
Title: Crystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitment.

Data show that Tnks1 and 2 are broadly expressed during mouse development and are essential during kidney and lung development. In the kidney, blockage of tankyrase activity phenocopies the effect of blocking production of all Wnt ligands.
Title: Tankyrase is necessary for canonical Wnt signaling during kidney development.

Tankyrase-deficient mice exhibit increases in energy expenditure, fatty acid oxidation, and insulin-stimulated glucose utilization.
Title: Hypermetabolism, hyperphagia, and reduced adiposity in tankyrase-deficient mice.

The following Tnks gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tnks cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04841	NM_175091.3 Latest version!	Mus musculus tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (Tnks), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tnks ( NM_175091.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_780300.2 Mus musculus tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (Tnks), mRNA.

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CloneID	OMu04841
Clone ID Related Accession (Same CDS sequence)	NM_175091.3
Accession Version	NM_175091.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3963bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-07
Organism	Mus musculus(house mouse)
Product	poly [ADP-ribose] polymerase tankyrase-1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK080913.1, BC057370.1 and AC122458.3. On or before Feb 16, 2006 this sequence version replaced NM_175322.2, NM_175091.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC057370.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGCGT CGCGTCGCTC TCAGCATCAT CACCACCATC ATCAGCAACA GCTCCAGCCC 
GCCCCAGGGG CTTCGGCTCC GCCACCGCCA CCTCCCCCGC CGCTCAGCCC GGGCTTGGCC 
CCGGGACCCA CCCCTGCCTC GCCTACGGCC GGCGGCCTGG CGCCCTTCGC CTCCCCGCGG 
CACGGCCTGG CGCTGCCGGA GGGGGATGGC AGCCGGGACC CGCCCGACAG GCCGCGATCT 
CCCGACCCGG TGGACGGCGC CGTCTGCACC GTGGCTGCTC CGGCCGCGGT CCCGGCAGCT 
TCCGCCGCCG TCGGGGTCGC TCCCACCCCA GCCGGCGGCG GCGGCGGCGG CGGGAACAAC 
TCCGCGTCGT CCGCTTCTTC CCCGACTTCG TCTTCGTCTT CCTCCCCGTC CTCCCCTGGC 
TCGAGCTTAG CGGAGAGTCC CGAGGCGGCC GGAGTTGGCT CCACGGCAAC TTTGGGAGCC 
GGGGCGGCGG GCCTCGGCCC GGGGGTCCCA GCCGTGAGTG GGGCCCTGCG GGAGCTGCTC 
GAGGCCTGTC GGAATGGGGA CGTGTCCCGG GTGAAGAGGT TGGTGGACGC CGCGAACGTG 
AATGCCAAGG ACATGGCCGG CCGAAAGTCT TCTCCCCTGC ACTTCGCAGC AGGTTTTGGA 
AGGAAGGATG TTGTAGAACA CTTGCTGCAG ATGGGTGCTA ATGTCCACGC CCGTGATGAC 
GGGGGTCTCA TCCCACTTCA TAATGCCTGC TCTTTCGGCC ATGCTGAGGT TGTGAGTCTG 
TTACTGTGTC AAGGAGCAGA TCCGAATGCC AGAGATAACT GGAACTATAC ACCACTGCAT 
GAAGCTGCCA TTAAAGGGAA AATTGATGTC TGTATTGTGC TGCTGCAGCA CGGAGCCGAT 
CCAAACATCC GGAACACCGA TGGGAAATCA GCTCTGGACC TGGCAGATCC TTCAGCAAAA 
GCTGTCCTCA CAGGTGAATA CAAAAAAGAC GAACTCCTAG AAGCTGCTAG GAGTGGTAAT 
GAAGAAAAAC TAATGGCTTT ACTGACTCCT CTAAATGTGA ATTGCCATGC AAGTGATGGA 
CGAAAGTCTA CTCCGTTACA CCTGGCAGCA GGCTACAACA GAGTTCGGAT AGTTCAGCTG 
CTTCTACAGC ATGGTGCTGA TGTCCACGCG AAAGACAAAG GTGGACTTGT ACCTCTTCAT 
AATGCATGCT CATACGGACA CTATGAGGTC ACAGAACTGC TGCTAAAGCA TGGAGCTTGT 
GTCAACGCTA TGGATCTGTG GCAGTTCACA CCGCTGCATG AAGCTGCTTC AAAGAACCGG 
GTAGAAGTCT GTTCTCTGTT ACTTAGTCAC GGTGCCGATC CAACCTTGGT CAATTGCCAT 
GGCAAAAGTG CTGTCGACAT GGCTCCAACT CCTGAGCTCC GGGAAAGACT GACATATGAA 
TTTAAAGGCC ATTCTTTACT CCAAGCCGCC AGAGAAGCAG ACCTGGCCAA AGTTAAAAAA 
ACGCTTGCTT TGGAAATCAT TAACTTCAAG CAGCCACAGT CTCATGAAAC TGCATTGCAC 
TGTGCTGTGG CCTCCTTGCA TCCCAAACGA AAGCAGGTGG CAGAGCTGTT ACTGAGGAAG 
GGAGCCAACG TCAACGAAAA GAACAAGGAT TTCATGACCC CTCTGCATGT TGCAGCTGAA 
AGAGCTCATA ATGATGTCAT GGAAGTTCTG CATAAGCACG GAGCAAAGAT GAATGCACTG 
GATAGTCTTG GTCAGACTGC TTTGCACAGA GCTGCCTTAG CGGGCCACCT GCAGACCTGC 
CGCCTCCTGC TGAGTTATGG CTCTGATCCT TCCATCATCT CCCTGCAAGG CTTCACGGCA 
GCGCAGATGG GGAATGAAGC AGTGCAACAG ATTCTGAGCG AGAGTACTCC TATGCGCACT 
TCGGACGTGG ACTATCGTCT CTTAGAGGCA TCGAAAGCTG GTGACTTGGA AACTGTGAAG 
CAACTCTGCA GCCCGCAGAA TGTGAACTGC AGAGACCTGG AGGGCCGGCA CTCTACACCC 
TTACACTTCG CTGCAGGCTA TAACCGTGTG TCTGTCGTTG AGTACCTTCT ACATCATGGA 
GCTGATGTCC ATGCCAAAGA CAAAGGTGGC TTGGTTCCCC TTCACAATGC CTGCTCCTAT 
GGACACTATG AGGTCGCCGA GCTCTTGGTG AGGCACGGGG CTTCAGTCAA TGTGGCCGAC 
CTGTGGAAAT TCACCCCTCT CCATGAAGCG GCAGCCAAGG GAAAATACGA AATCTGCAAA 
CTCCTTCTAA AACATGGAGC AGATCCAACT AAGAAGAACA GAGATGGAAA TACACCCCTA 
GATCTGGTCA AAGAAGGAGA CACGGATATT CAGGACCTGC TGAGGGGCGA TGCTGCCCTG 
TTGGATGCTG CCAAGAAGGG CTGCCTAGCC AGAGTGCAGA AGCTTTGTAC TCCAGAGAAT 
ATCAACTGCC GAGACACCCA GGGCAGAAAT TCAACCCCTC TCCACCTGGC AGCAGGCTAC 
AATAACCTGG AAGTAGCTGA GTACCTTCTA GAGCACGGGG CTGATGTCAA TGCCCAGGAC 
AAAGGAGGGC TAATCCCACT TCACAACGCT GCGTCTTATG GGCATGTTGA CATAGCAGCG 
TTACTGATAA AATACAACAC GTGTGTAAAC GCAACGGATA AGTGGGCCTT TACTCCCCTT 
CACGAAGCTG CCCAGAAAGG AAGGACGCAG TTATGTGCCC TGCTCCTAGC ACATGGCGCA 
GACCCAACCA TGAAGAACCA GGAAGGTCAG ACACCTTTAG ATCTGGCGAC GGCTGATGAC 
ATCCGGGCTC TGCTGATAGA TGCCATGCCC CCTGAGGCCT TACCTACCTG TTTTAAACCT 
CAGGCAACTG TAGTTAGTGC CTCTCTGATC TCACCAGCGT CCACCCCCTC CTGCCTCTCT 
GCTGCCAGCA GCATAGATAA CCTCACTGGC CCGTTAACGG ATCTGGCTGT AGGAGGGGCC 
TCCAATGCAG GGGATGGCGC TGCGGGTGCA GAAAGGAAGG AAGGAGAAGT TGCGGGTCTT 
GACATGAACA TCAGCCAGTT CCTTAAGAGC CTTGGCCTTG AGCACCTGAG GGACATTTTT 
GAAACAGAGC AGATTACGCT AGATGTGTTG GCTGATATGG GTCATGAAGA ATTGAAAGAA 
ATAGGCATCA ATGCATATGG ACACCGCCAC AAGTTGATCA AGGGTGTTGA AAGACTTTTA 
GGTGGACAAC AAGGAACCAA TCCATATTTG ACTTTTCACT GTGTGAATCA GGGAACTATT 
TTGCTAGATC TTGCTCCAGA AGATAAAGAA TATCAATCAG TAGAAGAAGA GATGCAGAGC 
ACTATTCGAG AGCACAGAGA CGGTGGGAAC GCTGGCGGCA TCTTCAACAG ATACAACGTC 
ATTCGAATTC AGAAAGTTGT GAATAAGAAG CTGAGGGAGC GATTCTGCCA CAGACAAAAG 
GAGGTGTCTG AGGAGAACCA CAACCATCAC AATGAGCGCA TGCTGTTCCA CGGTTCTCCT 
TTCATTAATG CAATTATTCA TAAAGGGTTT GATGAGCGAC ATGCGTACAT TGGAGGGATG 
TTTGGAGCTG GAATTTACTT TGCTGAAAAC TCCTCAAAAA GCAATCAGTA TGTTTATGGA 
ATTGGAGGAG GAACAGGCTG TCCCACACAC AAAGACAGAT CATGTTATAT ATGTCACAGA 
CAAATGCTTT TCTGTAGAGT GACCCTTGGA AAGTCCTTCC TGCAATTCAG CACCATGAAA 
ATGGCCCATG CACCCCCAGG CCATCACTCA GTCATCGGTA GACCAAGTGT CAATGGGCTG 
GCATATGCTG AATATGTCAT CTACAGAGGG GAACAGGCAT ATCCAGAATA TCTCATCACC 
TACCAGATCA TGAAGCCAGA AGCCCCTTCA CAGACCGCAA CGGCAGCAGA GCAGAAGACC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_780300.2
CDS	26..3988
Translation	MAASRRSQHHHHHHQQQLQPAPGASAPPPPPPPPLSPGLAPGPTPASPTAGGLAPFASPRHGLALPEGDGSRDPPDRPRSPDPVDGAVCTVAAPAAVPAASAAVGVAPTPAGGGGGGGNNSASSASSPTSSSSSSPSSPGSSLAESPEAAGVGSTATLGAGAAGLGPGVPAVSGALRELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPMRTSDVDYRLLEASKAGDLETVKQLCSPQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFKPQATVVSASLISPASTPSCLSAASSIDNLTGPLTDLAVGGASNAGDGAAGAERKEGEVAGLDMNISQFLKSLGLEHLRDIFETEQITLDVLADMGHEELKEIGINAYGHRHKLIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQKT

Target ORF information:

RefSeq Version	NM_175091.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (Tnks), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175091.3

ORF Insert Sequence:

ATGGCGGCGT CGCGTCGCTC TCAGCATCAT CACCACCATC ATCAGCAACA GCTCCAGCCC 
GCCCCAGGGG CTTCGGCTCC GCCACCGCCA CCTCCCCCGC CGCTCAGCCC GGGCTTGGCC 
CCGGGACCCA CCCCTGCCTC GCCTACGGCC GGCGGCCTGG CGCCCTTCGC CTCCCCGCGG 
CACGGCCTGG CGCTGCCGGA GGGGGATGGC AGCCGGGACC CGCCCGACAG GCCGCGATCT 
CCCGACCCGG TGGACGGCGC CGTCTGCACC GTGGCTGCTC CGGCCGCGGT CCCGGCAGCT 
TCCGCCGCCG TCGGGGTCGC TCCCACCCCA GCCGGCGGCG GCGGCGGCGG CGGGAACAAC 
TCCGCGTCGT CCGCTTCTTC CCCGACTTCG TCTTCGTCTT CCTCCCCGTC CTCCCCTGGC 
TCGAGCTTAG CGGAGAGTCC CGAGGCGGCC GGAGTTGGCT CCACGGCAAC TTTGGGAGCC 
GGGGCGGCGG GCCTCGGCCC GGGGGTCCCA GCCGTGAGTG GGGCCCTGCG GGAGCTGCTC 
GAGGCCTGTC GGAATGGGGA CGTGTCCCGG GTGAAGAGGT TGGTGGACGC CGCGAACGTG 
AATGCCAAGG ACATGGCCGG CCGAAAGTCT TCTCCCCTGC ACTTCGCAGC AGGTTTTGGA 
AGGAAGGATG TTGTAGAACA CTTGCTGCAG ATGGGTGCTA ATGTCCACGC CCGTGATGAC 
GGGGGTCTCA TCCCACTTCA TAATGCCTGC TCTTTCGGCC ATGCTGAGGT TGTGAGTCTG 
TTACTGTGTC AAGGAGCAGA TCCGAATGCC AGAGATAACT GGAACTATAC ACCACTGCAT 
GAAGCTGCCA TTAAAGGGAA AATTGATGTC TGTATTGTGC TGCTGCAGCA CGGAGCCGAT 
CCAAACATCC GGAACACCGA TGGGAAATCA GCTCTGGACC TGGCAGATCC TTCAGCAAAA 
GCTGTCCTCA CAGGTGAATA CAAAAAAGAC GAACTCCTAG AAGCTGCTAG GAGTGGTAAT 
GAAGAAAAAC TAATGGCTTT ACTGACTCCT CTAAATGTGA ATTGCCATGC AAGTGATGGA 
CGAAAGTCTA CTCCGTTACA CCTGGCAGCA GGCTACAACA GAGTTCGGAT AGTTCAGCTG 
CTTCTACAGC ATGGTGCTGA TGTCCACGCG AAAGACAAAG GTGGACTTGT ACCTCTTCAT 
AATGCATGCT CATACGGACA CTATGAGGTC ACAGAACTGC TGCTAAAGCA TGGAGCTTGT 
GTCAACGCTA TGGATCTGTG GCAGTTCACA CCGCTGCATG AAGCTGCTTC AAAGAACCGG 
GTAGAAGTCT GTTCTCTGTT ACTTAGTCAC GGTGCCGATC CAACCTTGGT CAATTGCCAT 
GGCAAAAGTG CTGTCGACAT GGCTCCAACT CCTGAGCTCC GGGAAAGACT GACATATGAA 
TTTAAAGGCC ATTCTTTACT CCAAGCCGCC AGAGAAGCAG ACCTGGCCAA AGTTAAAAAA 
ACGCTTGCTT TGGAAATCAT TAACTTCAAG CAGCCACAGT CTCATGAAAC TGCATTGCAC 
TGTGCTGTGG CCTCCTTGCA TCCCAAACGA AAGCAGGTGG CAGAGCTGTT ACTGAGGAAG 
GGAGCCAACG TCAACGAAAA GAACAAGGAT TTCATGACCC CTCTGCATGT TGCAGCTGAA 
AGAGCTCATA ATGATGTCAT GGAAGTTCTG CATAAGCACG GAGCAAAGAT GAATGCACTG 
GATAGTCTTG GTCAGACTGC TTTGCACAGA GCTGCCTTAG CGGGCCACCT GCAGACCTGC 
CGCCTCCTGC TGAGTTATGG CTCTGATCCT TCCATCATCT CCCTGCAAGG CTTCACGGCA 
GCGCAGATGG GGAATGAAGC AGTGCAACAG ATTCTGAGCG AGAGTACTCC TATGCGCACT 
TCGGACGTGG ACTATCGTCT CTTAGAGGCA TCGAAAGCTG GTGACTTGGA AACTGTGAAG 
CAACTCTGCA GCCCGCAGAA TGTGAACTGC AGAGACCTGG AGGGCCGGCA CTCTACACCC 
TTACACTTCG CTGCAGGCTA TAACCGTGTG TCTGTCGTTG AGTACCTTCT ACATCATGGA 
GCTGATGTCC ATGCCAAAGA CAAAGGTGGC TTGGTTCCCC TTCACAATGC CTGCTCCTAT 
GGACACTATG AGGTCGCCGA GCTCTTGGTG AGGCACGGGG CTTCAGTCAA TGTGGCCGAC 
CTGTGGAAAT TCACCCCTCT CCATGAAGCG GCAGCCAAGG GAAAATACGA AATCTGCAAA 
CTCCTTCTAA AACATGGAGC AGATCCAACT AAGAAGAACA GAGATGGAAA TACACCCCTA 
GATCTGGTCA AAGAAGGAGA CACGGATATT CAGGACCTGC TGAGGGGCGA TGCTGCCCTG 
TTGGATGCTG CCAAGAAGGG CTGCCTAGCC AGAGTGCAGA AGCTTTGTAC TCCAGAGAAT 
ATCAACTGCC GAGACACCCA GGGCAGAAAT TCAACCCCTC TCCACCTGGC AGCAGGCTAC 
AATAACCTGG AAGTAGCTGA GTACCTTCTA GAGCACGGGG CTGATGTCAA TGCCCAGGAC 
AAAGGAGGGC TAATCCCACT TCACAACGCT GCGTCTTATG GGCATGTTGA CATAGCAGCG 
TTACTGATAA AATACAACAC GTGTGTAAAC GCAACGGATA AGTGGGCCTT TACTCCCCTT 
CACGAAGCTG CCCAGAAAGG AAGGACGCAG TTATGTGCCC TGCTCCTAGC ACATGGCGCA 
GACCCAACCA TGAAGAACCA GGAAGGTCAG ACACCTTTAG ATCTGGCGAC GGCTGATGAC 
ATCCGGGCTC TGCTGATAGA TGCCATGCCC CCTGAGGCCT TACCTACCTG TTTTAAACCT 
CAGGCAACTG TAGTTAGTGC CTCTCTGATC TCACCAGCGT CCACCCCCTC CTGCCTCTCT 
GCTGCCAGCA GCATAGATAA CCTCACTGGC CCGTTAACGG ATCTGGCTGT AGGAGGGGCC 
TCCAATGCAG GGGATGGCGC TGCGGGTGCA GAAAGGAAGG AAGGAGAAGT TGCGGGTCTT 
GACATGAACA TCAGCCAGTT CCTTAAGAGC CTTGGCCTTG AGCACCTGAG GGACATTTTT 
GAAACAGAGC AGATTACGCT AGATGTGTTG GCTGATATGG GTCATGAAGA ATTGAAAGAA 
ATAGGCATCA ATGCATATGG ACACCGCCAC AAGTTGATCA AGGGTGTTGA AAGACTTTTA 
GGTGGACAAC AAGGAACCAA TCCATATTTG ACTTTTCACT GTGTGAATCA GGGAACTATT 
TTGCTAGATC TTGCTCCAGA AGATAAAGAA TATCAATCAG TAGAAGAAGA GATGCAGAGC 
ACTATTCGAG AGCACAGAGA CGGTGGGAAC GCTGGCGGCA TCTTCAACAG ATACAACGTC 
ATTCGAATTC AGAAAGTTGT GAATAAGAAG CTGAGGGAGC GATTCTGCCA CAGACAAAAG 
GAGGTGTCTG AGGAGAACCA CAACCATCAC AATGAGCGCA TGCTGTTCCA CGGTTCTCCT 
TTCATTAATG CAATTATTCA TAAAGGGTTT GATGAGCGAC ATGCGTACAT TGGAGGGATG 
TTTGGAGCTG GAATTTACTT TGCTGAAAAC TCCTCAAAAA GCAATCAGTA TGTTTATGGA 
ATTGGAGGAG GAACAGGCTG TCCCACACAC AAAGACAGAT CATGTTATAT ATGTCACAGA 
CAAATGCTTT TCTGTAGAGT GACCCTTGGA AAGTCCTTCC TGCAATTCAG CACCATGAAA 
ATGGCCCATG CACCCCCAGG CCATCACTCA GTCATCGGTA GACCAAGTGT CAATGGGCTG 
GCATATGCTG AATATGTCAT CTACAGAGGG GAACAGGCAT ATCCAGAATA TCTCATCACC 
TACCAGATCA TGAAGCCAGA AGCCCCTTCA CAGACCGCAA CGGCAGCAGA GCAGAAGACC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structural insights into SAM domain-mediated tankyrase oligomerization.
Protein science : a publication of the Protein Society25(9)1744-52(2016 Sep)
DaRosa PA,Ovchinnikov S,Xu W,Klevit RE

Tankyrase inhibition aggravates kidney injury in the absence of CD2AP.
Cell death & disease7e2302(2016 Jul)
Kuusela S,Wang H,Wasik AA,Suleiman H,Lehtonen S

Integrative genomic approach identifies multiple genes involved in cardiac collagen deposition.
Circulation. Cardiovascular genetics7(6)790-8(2014 Dec)
Lodder EM,Scicluna BP,Beekman L,Arends D,Moerland PD,Tanck MW,Adriaens ME,Bezzina CR

mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.
Neuron78(6)1012-23(2013 Jun)
Wentzel C,Sommer JE,Nair R,Stiefvater A,Sibarita JB,Scheiffele P

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Tnks cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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