Tgfbr3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tgfbr3
Entrez Gene ID	21814
Full Name	transforming growth factor, beta receptor III
Synonyms	1110036H20Rik,AU015626,AW215636,TBRIII
General protein information	Preferred Names transforming growth factor, beta receptor III Names transforming growth factor beta receptor type 3 TGF-beta receptor type 3 TGF-beta receptor type III TGFR-3 betaglycan
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 E5

mRNA and Protein(s)

mRNA	Protein	Name
NM_011578.3	NP_035708.2	transforming growth factor beta receptor type 3 precursor
NM_011578.4	NP_035708.2	transforming growth factor beta receptor type 3 precursor

Pathways from BioSystems

Homologies

	TGFBR3	XP_001098070.1
Gallus gallus (chicken)	TGFBR3	NP_989670.1
Pan troglodytes (chimpanzee)	TGFBR3	XP_513555.2
Danio rerio (zebrafish)	tgfbr3	XP_002662477.3
Canis lupus familiaris (dog)	TGFBR3	XP_005621992.1
Bos taurus (cattle)	TGFBR3	XP_005204393.1
Homo sapiens (human)	TGFBR3	NP_003234.2
Xenopus tropicalis (tropical clawed frog)	tgfbr3	XP_002933852.2
Mus musculus (house mouse)	Tgfbr3	NP_035708.2
Rattus norvegicus (Norway rat)	Tgfbr3	NP_058952.1

Gene Ontology
Bibliography

Related articles in PubMed

T?RIII is induced by TCR signaling and downregulated in FoxP3
Ortega-Francisco S, de la Fuente-Granada M, Alvarez Salazar EK, Bola?os-Castro LA, Fonseca-Camarillo G, Olguin-Alor R, Alem?n-Muench GR, L?pez-Casillas F, Raman C, Garc?a-Zepeda EA, Soldevila G
Biochemical and biophysical research communications494(1-2)82-87(2017 12)

Transforming Growth Factor-? Receptor III is a Potential Regulator of Ischemia-Induced Cardiomyocyte Apoptosis.
Sun F, Li X, Duan WQ, Tian W, Gao M, Yang J, Wu XY, Huang D, Xia W, Han YN, Wang JX, Liu YX, Dong CJ, Zhao D, Ban T, Chu WF
Journal of the American Heart Association6(6)(2017 May)

Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGF?R3 In Vitro.
DeLaughter DM, Clark CR, Christodoulou DC, Seidman CE, Baldwin HS, Seidman JG, Barnett JV
PloS one11(8)e0159710(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

describe a detailed characterization of TbetaRIII expression in lymphocyte subpopulations demonstrating that this co-receptor is significantly expressed in T but not B lymphocytes and among them, preferentially expressed on naive and central memory T cells
Title: T?RIII is induced by TCR signaling and downregulated in FoxP3

Retinoic acid enhanced TbetaRIII expression and that this increase contributed to LF-stimulated IgA production.
Title: Retinoic acid enhances lactoferrin-induced IgA responses by increasing betaglycan expression.

BMP2 also requires Src for filamentous actin polymerization in Tgfbr3(-/-) epicardial cells.
Title: BMP2 rescues deficient cell migration in Tgfbr3(-/-) epicardial cells and requires Src kinase.

a signaling pathway important in epicardial cell behavior downstream of TGFbetaR3
Title: Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGF?R3 In Vitro.

Pro-fibrotic cardiac effect of miR-328 was mediated by down-regulating TGFbR3 and up-regulating TGFb1.
Title: MicroRNA-328, a Potential Anti-Fibrotic Target in Cardiac Interstitial Fibrosis.

The following Tgfbr3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tgfbr3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu22483	NM_011578.4 Latest version!	Mus musculus transforming growth factor, beta receptor III (Tgfbr3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$475.30 $679.00
View Old Accession Versions >>
OMu22483	NM_011578.3	Mus musculus transforming growth factor, beta receptor III (Tgfbr3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$475.30 $679.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tgfbr3 ( NM_011578.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035708.2 Mus musculus transforming growth factor, beta receptor III (Tgfbr3), mRNA.

Price & Availability↑

CloneID	OMu22483
Clone ID Related Accession (Same CDS sequence)	NM_011578.3 , NM_011578.4
Accession Version	NM_011578.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2553bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-14
Organism	Mus musculus(House mouse)
Product	transforming growth factor beta receptor type 3 precursor
Comment

ATGGCAGTGA CATCCCACCA CATGGTCCCT GTGTTTGTCC TGATGAGCGC CTGCCTGGCC 
ACCGCAGGTC CAGAGCCCAG CACCCGGTGT GAACTGTCAC CGATCAGTGC CTCTCATCCA 
GTCCAGGCCC TGATGGAGAG CTTCACCGTT CTGTCTGGCT GTGCCAGCAG AGGCACCACT 
GGGCTGCCAA GGGAGGTTCA CATCCTAAAC CTCCGCAGTA CAGACCAAGG ACTAGGCCAG 
CCGCAGAGAG AGGTTACCCT GCATCTGAAC CCCATTGCCT CCGTGCACAC TCACCACAAG 
CCTGTTGTGT TCCTGCTCAA CTCCCCACAG CCCCTGGTGT GGCATGTGAA GACAGAGAGA 
CTGGCTGCTG GTGTCCCCAG ACTCTTCCTG GTTTCGGAGG GTTCTGTGGT CCAGTTTTCA 
TCAGGAAACT TCTCCTTGAC AGCAGAAACA GAGGAAAGGA GTTTCCCTCA AGAAAATGAG 
CATCTGCTAC ACTGGGCCCA AAAGGAATAT GGAGCAGTGA CTTCATTCAC CGAACTTAAG 
ATAGCAAGAA ATATCTATAT TAAAGTGGGA GAAGATCAAG TGTTCCCTCC CACGTGTAAC 
ATAGGGAAAA ATTTTCTCTC GCTCAATTAC CTTGCGGAGT ACCTTCAACC CAAAGCCGCC 
GAAGGTTGTG TCCTGGCCAG TCAGCCCCAC GAGAAGGAAG TGCATATCAT TGAGTTAATC 
TCCCCCAACT CCAATCCTTA CAGCACCTTC CAGGTGGATA TAATAATTGA CATACGACCT 
GCTCGAGAGG ATCCTGAGGT GGTCAAAAAC CTCGTCCTGA TCTTGAAGTG CAAAAAATCT 
GTCAACTGGG TGATCAAGTC TTTTGACGTC AAGGGAAACT TGAAAGTTAT TGCTCCTGAC 
AGTATTGGCT TTGGAAAAGA GAGTGAACGA TCCATGACAG TGACCAAATT GGTAAGAAAT 
GACATCCCTT CCACCCAAGA GAATCTGATG AAGTGGGCAT TGGACAATGG CTACAGCCCA 
GTGACGTCAT ACACCATAGC TCCTGTGGCC AATAGATTTC ATCTTCGGCT TGAGAACAAC 
GAGGAGATGA GAGATGAGGA AGTCCACACC ATTCCTCCTG AGCTTCGGAT CCTGCTGGGC 
CCTGACCACC TGCCTGCCCT GGACAGCCCA TCCTTCCAAG GGGAAATCCC AAATGGAGGT 
TTCCCCTTCC CATTCCCGGA TATCCCCAGG AGAGGCTGGA AGGAGGGAGA AGATAGGATC 
CCCCGGCCAA AGGAACCCAT CATTCCCAGA GTTCAATTGC TTCCAGACCA CAGAGAGCCA 
GAAGAAGTGC AAGGGGGCGT GAATATCGCC CTGTCAGTCA AATGTGACAA TGAAAAGATG 
GTGGTAGCTG TAGACAAAGA TTCTTTCCAG ACCAATGGCT ACTCGGGGAT GGAGCTCACC 
CTGTTGGATC CTTCCTGCAA AGCCAAGATG AATGGTACCC ACTTTGTACT GGAGTCTCCG 
CTGAATGGCT GTGGTACTAG ACATAGGAGG TCAGCCCCAG ATGGTGTGGT TTACTATAAC 
TCTATTGTGG TGCAGGCTCC ATCCCCTGGG GATAGCAGTG GCTGGCCAGA CGGCTACGAA 
GATTTGGAGT CGGGTGATAA TGGATTTCCT GGAGACACAG ATGAAGGAGA AACTGCCCCC 
CTGAGCCGTG CTGGAGTGGT AGTGTTTAAC TGCAGCTTGC GGCAGCTGAG GAGTCCCAGT 
GGCTTCCAGG ACCAGCTCGA TGGAAATGCT ACCTTCAACA TGGAGCTGTA TAACACAGAC 
CTCTTTCTGG TGCCCTCCCC AGGGGTCTTC TCTGTGGCAG AGAATGAGCA TGTATATGTT 
GAGGTGTCTG TCACTAAGGC TGACCAAGAT CTGGGATTTG CCATCCAAAC CTGCTTTATC 
TCTCCATACT CAAACCCAGA CAGAATGTCT GATTACACCA TCATCGAGAA CATCTGTCCG 
AAGGATGACT CTGTGAAGTT CTACAGCTCC AAGAGAGTGC ACTTCCCCAT CCCACATGCT 
GAAGTGGACA AGAAGCGGTT CAGCTTTGTG TTCAAGTCCG TGTTCAACAC CTCCCTGCTC 
TTCCTGCACT GCGAGCTGAC GCTGTGCTCT AGGAAGAAGG GCTCCCAGAA GCTGCCAAAG 
TGTGTGACTC CTGACGACGC CTGCACCTCT CTAGATGCCA CCATGATCTG GACCATGATG 
CAGAATAAGA AGACATTCAC CAAGCCCCTG GCCGTGGTCC TCCAAGTAGA TTATAAAGAA 
AATGTTCCAA ACATGAAGGA GTCCAGTCCG GTTCCTCCTC CTCCACAGAT TTTCCACGGC 
CTGGACACGC TCACCGTGAT GGGCATTGCG TTTGCAGCAT TTGTGATCGG AGCACTCCTG 
ACGGGGGCCT TGTGGTATAT CTACTCCCAC ACAGGGGAGA CGGCACGAAG GCAGCAAGTC 
CCTACCTCGC CACCAGCCTC GGAGAACAGC AGCGCAGCCC ACAGCATAGG GAGCACTCAG 
AGCACTCCCT GCTCTAGCAG CAGCACGGCC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_035708.2

Translation

MAVTSHHMVPVFVLMSACLATAGPEPSTRCELSPISASHPVQALMESFTVLSGCASRGTTGLPREVHILNLRSTDQGLGQPQREVTLHLNPIASVHTHHKPVVFLLNSPQPLVWHVKTERLAAGVPRLFLVSEGSVVQFSSGNFSLTAETEERSFPQENEHLLHWAQKEYGAVTSFTELKIARNIYIKVGEDQVFPPTCNIGKNFLSLNYLAEYLQPKAAEGCVLASQPHEKEVHIIELISPNSNPYSTFQVDIIIDIRPAREDPEVVKNLVLILKCKKSVNWVIKSFDVKGNLKVIAPDSIGFGKESERSMTVTKLVRNDIPSTQENLMKWALDNGYSPVTSYTIAPVANRFHLRLENNEEMRDEEVHTIPPELRILLGPDHLPALDSPSFQGEIPNGGFPFPFPDIPRRGWKEGEDRIPRPKEPIIPRVQLLPDHREPEEVQGGVNIALSVKCDNEKMVVAVDKDSFQTNGYSGMELTLLDPSCKAKMNGTHFVLESPLNGCGTRHRRSAPDGVVYYNSIVVQAPSPGDSSGWPDGYEDLESGDNGFPGDTDEGETAPLSRAGVVVFNCSLRQLRSPSGFQDQLDGNATFNMELYNTDLFLVPSPGVFSVAENEHVYVEVSVTKADQDLGFAIQTCFISPYSNPDRMSDYTIIENICPKDDSVKFYSSKRVHFPIPHAEVDKKRFSFVFKSVFNTSLLFLHCELTLCSRKKGSQKLPKCVTPDDACTSLDATMIWTMMQNKKTFTKPLAVVLQVDYKENVPNMKESSPVPPPPQIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETARRQQVPTSPPASENSSAAHSIGSTQSTPCSSSSTA

Target ORF information:

RefSeq Version	NM_011578.3
Organism	Mus musculus(House mouse)
Definition	Mus musculus transforming growth factor, beta receptor III (Tgfbr3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011578.3

ORF Insert Sequence:

ATGGCAGTGA CATCCCACCA CATGGTCCCT GTGTTTGTCC TGATGAGCGC CTGCCTGGCC 
ACCGCAGGTC CAGAGCCCAG CACCCGGTGT GAACTGTCAC CGATCAGTGC CTCTCATCCA 
GTCCAGGCCC TGATGGAGAG CTTCACCGTT CTGTCTGGCT GTGCCAGCAG AGGCACCACT 
GGGCTGCCAA GGGAGGTTCA CATCCTAAAC CTCCGCAGTA CAGACCAAGG ACTAGGCCAG 
CCGCAGAGAG AGGTTACCCT GCATCTGAAC CCCATTGCCT CCGTGCACAC TCACCACAAG 
CCTGTTGTGT TCCTGCTCAA CTCCCCACAG CCCCTGGTGT GGCATGTGAA GACAGAGAGA 
CTGGCTGCTG GTGTCCCCAG ACTCTTCCTG GTTTCGGAGG GTTCTGTGGT CCAGTTTTCA 
TCAGGAAACT TCTCCTTGAC AGCAGAAACA GAGGAAAGGA GTTTCCCTCA AGAAAATGAG 
CATCTGCTAC ACTGGGCCCA AAAGGAATAT GGAGCAGTGA CTTCATTCAC CGAACTTAAG 
ATAGCAAGAA ATATCTATAT TAAAGTGGGA GAAGATCAAG TGTTCCCTCC CACGTGTAAC 
ATAGGGAAAA ATTTTCTCTC GCTCAATTAC CTTGCGGAGT ACCTTCAACC CAAAGCCGCC 
GAAGGTTGTG TCCTGGCCAG TCAGCCCCAC GAGAAGGAAG TGCATATCAT TGAGTTAATC 
TCCCCCAACT CCAATCCTTA CAGCACCTTC CAGGTGGATA TAATAATTGA CATACGACCT 
GCTCGAGAGG ATCCTGAGGT GGTCAAAAAC CTCGTCCTGA TCTTGAAGTG CAAAAAATCT 
GTCAACTGGG TGATCAAGTC TTTTGACGTC AAGGGAAACT TGAAAGTTAT TGCTCCTGAC 
AGTATTGGCT TTGGAAAAGA GAGTGAACGA TCCATGACAG TGACCAAATT GGTAAGAAAT 
GACATCCCTT CCACCCAAGA GAATCTGATG AAGTGGGCAT TGGACAATGG CTACAGCCCA 
GTGACGTCAT ACACCATAGC TCCTGTGGCC AATAGATTTC ATCTTCGGCT TGAGAACAAC 
GAGGAGATGA GAGATGAGGA AGTCCACACC ATTCCTCCTG AGCTTCGGAT CCTGCTGGGC 
CCTGACCACC TGCCTGCCCT GGACAGCCCA TCCTTCCAAG GGGAAATCCC AAATGGAGGT 
TTCCCCTTCC CATTCCCGGA TATCCCCAGG AGAGGCTGGA AGGAGGGAGA AGATAGGATC 
CCCCGGCCAA AGGAACCCAT CATTCCCAGA GTTCAATTGC TTCCAGACCA CAGAGAGCCA 
GAAGAAGTGC AAGGGGGCGT GAATATCGCC CTGTCAGTCA AATGTGACAA TGAAAAGATG 
GTGGTAGCTG TAGACAAAGA TTCTTTCCAG ACCAATGGCT ACTCGGGGAT GGAGCTCACC 
CTGTTGGATC CTTCCTGCAA AGCCAAGATG AATGGTACCC ACTTTGTACT GGAGTCTCCG 
CTGAATGGCT GTGGTACTAG ACATAGGAGG TCAGCCCCAG ATGGTGTGGT TTACTATAAC 
TCTATTGTGG TGCAGGCTCC ATCCCCTGGG GATAGCAGTG GCTGGCCAGA CGGCTACGAA 
GATTTGGAGT CGGGTGATAA TGGATTTCCT GGAGACACAG ATGAAGGAGA AACTGCCCCC 
CTGAGCCGTG CTGGAGTGGT AGTGTTTAAC TGCAGCTTGC GGCAGCTGAG GAGTCCCAGT 
GGCTTCCAGG ACCAGCTCGA TGGAAATGCT ACCTTCAACA TGGAGCTGTA TAACACAGAC 
CTCTTTCTGG TGCCCTCCCC AGGGGTCTTC TCTGTGGCAG AGAATGAGCA TGTATATGTT 
GAGGTGTCTG TCACTAAGGC TGACCAAGAT CTGGGATTTG CCATCCAAAC CTGCTTTATC 
TCTCCATACT CAAACCCAGA CAGAATGTCT GATTACACCA TCATCGAGAA CATCTGTCCG 
AAGGATGACT CTGTGAAGTT CTACAGCTCC AAGAGAGTGC ACTTCCCCAT CCCACATGCT 
GAAGTGGACA AGAAGCGGTT CAGCTTTGTG TTCAAGTCCG TGTTCAACAC CTCCCTGCTC 
TTCCTGCACT GCGAGCTGAC GCTGTGCTCT AGGAAGAAGG GCTCCCAGAA GCTGCCAAAG 
TGTGTGACTC CTGACGACGC CTGCACCTCT CTAGATGCCA CCATGATCTG GACCATGATG 
CAGAATAAGA AGACATTCAC CAAGCCCCTG GCCGTGGTCC TCCAAGTAGA TTATAAAGAA 
AATGTTCCAA ACATGAAGGA GTCCAGTCCG GTTCCTCCTC CTCCACAGAT TTTCCACGGC 
CTGGACACGC TCACCGTGAT GGGCATTGCG TTTGCAGCAT TTGTGATCGG AGCACTCCTG 
ACGGGGGCCT TGTGGTATAT CTACTCCCAC ACAGGGGAGA CGGCACGAAG GCAGCAAGTC 
CCTACCTCGC CACCAGCCTC GGAGAACAGC AGCGCAGCCC ACAGCATAGG GAGCACTCAG 
AGCACTCCCT GCTCTAGCAG CAGCACGGCC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tgfbr3 ( NM_011578.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035708.2 Mus musculus transforming growth factor, beta receptor III (Tgfbr3), mRNA.

Price & Availability↑

CloneID	OMu22483
Clone ID Related Accession (Same CDS sequence)	NM_011578.3 , NM_011578.4
Accession Version	NM_011578.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2553bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Mus musculus(house mouse)
Product	transforming growth factor beta receptor type 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC133897.15 and AC166776.6. On Jan 5, 2017 this sequence version replaced NM_011578.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC070428.1, AF039601.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGTGA CATCCCACCA CATGGTCCCT GTGTTTGTCC TGATGAGCGC CTGCCTGGCC 
ACCGCAGGTC CAGAGCCCAG CACCCGGTGT GAACTGTCAC CGATCAGTGC CTCTCATCCA 
GTCCAGGCCC TGATGGAGAG CTTCACCGTT CTGTCTGGCT GTGCCAGCAG AGGCACCACT 
GGGCTGCCAA GGGAGGTTCA CATCCTAAAC CTCCGCAGTA CAGACCAAGG ACTAGGCCAG 
CCGCAGAGAG AGGTTACCCT GCATCTGAAC CCCATTGCCT CCGTGCACAC TCACCACAAG 
CCTGTTGTGT TCCTGCTCAA CTCCCCACAG CCCCTGGTGT GGCATGTGAA GACAGAGAGA 
CTGGCTGCTG GTGTCCCCAG ACTCTTCCTG GTTTCGGAGG GTTCTGTGGT CCAGTTTTCA 
TCAGGAAACT TCTCCTTGAC AGCAGAAACA GAGGAAAGGA GTTTCCCTCA AGAAAATGAG 
CATCTGCTAC ACTGGGCCCA AAAGGAATAT GGAGCAGTGA CTTCATTCAC CGAACTTAAG 
ATAGCAAGAA ATATCTATAT TAAAGTGGGA GAAGATCAAG TGTTCCCTCC CACGTGTAAC 
ATAGGGAAAA ATTTTCTCTC GCTCAATTAC CTTGCGGAGT ACCTTCAACC CAAAGCCGCC 
GAAGGTTGTG TCCTGGCCAG TCAGCCCCAC GAGAAGGAAG TGCATATCAT TGAGTTAATC 
TCCCCCAACT CCAATCCTTA CAGCACCTTC CAGGTGGATA TAATAATTGA CATACGACCT 
GCTCGAGAGG ATCCTGAGGT GGTCAAAAAC CTCGTCCTGA TCTTGAAGTG CAAAAAATCT 
GTCAACTGGG TGATCAAGTC TTTTGACGTC AAGGGAAACT TGAAAGTTAT TGCTCCTGAC 
AGTATTGGCT TTGGAAAAGA GAGTGAACGA TCCATGACAG TGACCAAATT GGTAAGAAAT 
GACATCCCTT CCACCCAAGA GAATCTGATG AAGTGGGCAT TGGACAATGG CTACAGCCCA 
GTGACGTCAT ACACCATAGC TCCTGTGGCC AATAGATTTC ATCTTCGGCT TGAGAACAAC 
GAGGAGATGA GAGATGAGGA AGTCCACACC ATTCCTCCTG AGCTTCGGAT CCTGCTGGGC 
CCTGACCACC TGCCTGCCCT GGACAGCCCA TCCTTCCAAG GGGAAATCCC AAATGGAGGT 
TTCCCCTTCC CATTCCCGGA TATCCCCAGG AGAGGCTGGA AGGAGGGAGA AGATAGGATC 
CCCCGGCCAA AGGAACCCAT CATTCCCAGA GTTCAATTGC TTCCAGACCA CAGAGAGCCA 
GAAGAAGTGC AAGGGGGCGT GAATATCGCC CTGTCAGTCA AATGTGACAA TGAAAAGATG 
GTGGTAGCTG TAGACAAAGA TTCTTTCCAG ACCAATGGCT ACTCGGGGAT GGAGCTCACC 
CTGTTGGATC CTTCCTGCAA AGCCAAGATG AATGGTACCC ACTTTGTACT GGAGTCTCCG 
CTGAATGGCT GTGGTACTAG ACATAGGAGG TCAGCCCCAG ATGGTGTGGT TTACTATAAC 
TCTATTGTGG TGCAGGCTCC ATCCCCTGGG GATAGCAGTG GCTGGCCAGA CGGCTACGAA 
GATTTGGAGT CGGGTGATAA TGGATTTCCT GGAGACACAG ATGAAGGAGA AACTGCCCCC 
CTGAGCCGTG CTGGAGTGGT AGTGTTTAAC TGCAGCTTGC GGCAGCTGAG GAGTCCCAGT 
GGCTTCCAGG ACCAGCTCGA TGGAAATGCT ACCTTCAACA TGGAGCTGTA TAACACAGAC 
CTCTTTCTGG TGCCCTCCCC AGGGGTCTTC TCTGTGGCAG AGAATGAGCA TGTATATGTT 
GAGGTGTCTG TCACTAAGGC TGACCAAGAT CTGGGATTTG CCATCCAAAC CTGCTTTATC 
TCTCCATACT CAAACCCAGA CAGAATGTCT GATTACACCA TCATCGAGAA CATCTGTCCG 
AAGGATGACT CTGTGAAGTT CTACAGCTCC AAGAGAGTGC ACTTCCCCAT CCCACATGCT 
GAAGTGGACA AGAAGCGGTT CAGCTTTGTG TTCAAGTCCG TGTTCAACAC CTCCCTGCTC 
TTCCTGCACT GCGAGCTGAC GCTGTGCTCT AGGAAGAAGG GCTCCCAGAA GCTGCCAAAG 
TGTGTGACTC CTGACGACGC CTGCACCTCT CTAGATGCCA CCATGATCTG GACCATGATG 
CAGAATAAGA AGACATTCAC CAAGCCCCTG GCCGTGGTCC TCCAAGTAGA TTATAAAGAA 
AATGTTCCAA ACATGAAGGA GTCCAGTCCG GTTCCTCCTC CTCCACAGAT TTTCCACGGC 
CTGGACACGC TCACCGTGAT GGGCATTGCG TTTGCAGCAT TTGTGATCGG AGCACTCCTG 
ACGGGGGCCT TGTGGTATAT CTACTCCCAC ACAGGGGAGA CGGCACGAAG GCAGCAAGTC 
CCTACCTCGC CACCAGCCTC GGAGAACAGC AGCGCAGCCC ACAGCATAGG GAGCACTCAG 
AGCACTCCCT GCTCTAGCAG CAGCACGGCC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035708.2
CDS	466..3018
Translation	MAVTSHHMVPVFVLMSACLATAGPEPSTRCELSPISASHPVQALMESFTVLSGCASRGTTGLPREVHILNLRSTDQGLGQPQREVTLHLNPIASVHTHHKPVVFLLNSPQPLVWHVKTERLAAGVPRLFLVSEGSVVQFSSGNFSLTAETEERSFPQENEHLLHWAQKEYGAVTSFTELKIARNIYIKVGEDQVFPPTCNIGKNFLSLNYLAEYLQPKAAEGCVLASQPHEKEVHIIELISPNSNPYSTFQVDIIIDIRPAREDPEVVKNLVLILKCKKSVNWVIKSFDVKGNLKVIAPDSIGFGKESERSMTVTKLVRNDIPSTQENLMKWALDNGYSPVTSYTIAPVANRFHLRLENNEEMRDEEVHTIPPELRILLGPDHLPALDSPSFQGEIPNGGFPFPFPDIPRRGWKEGEDRIPRPKEPIIPRVQLLPDHREPEEVQGGVNIALSVKCDNEKMVVAVDKDSFQTNGYSGMELTLLDPSCKAKMNGTHFVLESPLNGCGTRHRRSAPDGVVYYNSIVVQAPSPGDSSGWPDGYEDLESGDNGFPGDTDEGETAPLSRAGVVVFNCSLRQLRSPSGFQDQLDGNATFNMELYNTDLFLVPSPGVFSVAENEHVYVEVSVTKADQDLGFAIQTCFISPYSNPDRMSDYTIIENICPKDDSVKFYSSKRVHFPIPHAEVDKKRFSFVFKSVFNTSLLFLHCELTLCSRKKGSQKLPKCVTPDDACTSLDATMIWTMMQNKKTFTKPLAVVLQVDYKENVPNMKESSPVPPPPQIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETARRQQVPTSPPASENSSAAHSIGSTQSTPCSSSSTA

Target ORF information:

RefSeq Version	NM_011578.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus transforming growth factor, beta receptor III (Tgfbr3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011578.4

ORF Insert Sequence:

ATGGCAGTGA CATCCCACCA CATGGTCCCT GTGTTTGTCC TGATGAGCGC CTGCCTGGCC 
ACCGCAGGTC CAGAGCCCAG CACCCGGTGT GAACTGTCAC CGATCAGTGC CTCTCATCCA 
GTCCAGGCCC TGATGGAGAG CTTCACCGTT CTGTCTGGCT GTGCCAGCAG AGGCACCACT 
GGGCTGCCAA GGGAGGTTCA CATCCTAAAC CTCCGCAGTA CAGACCAAGG ACTAGGCCAG 
CCGCAGAGAG AGGTTACCCT GCATCTGAAC CCCATTGCCT CCGTGCACAC TCACCACAAG 
CCTGTTGTGT TCCTGCTCAA CTCCCCACAG CCCCTGGTGT GGCATGTGAA GACAGAGAGA 
CTGGCTGCTG GTGTCCCCAG ACTCTTCCTG GTTTCGGAGG GTTCTGTGGT CCAGTTTTCA 
TCAGGAAACT TCTCCTTGAC AGCAGAAACA GAGGAAAGGA GTTTCCCTCA AGAAAATGAG 
CATCTGCTAC ACTGGGCCCA AAAGGAATAT GGAGCAGTGA CTTCATTCAC CGAACTTAAG 
ATAGCAAGAA ATATCTATAT TAAAGTGGGA GAAGATCAAG TGTTCCCTCC CACGTGTAAC 
ATAGGGAAAA ATTTTCTCTC GCTCAATTAC CTTGCGGAGT ACCTTCAACC CAAAGCCGCC 
GAAGGTTGTG TCCTGGCCAG TCAGCCCCAC GAGAAGGAAG TGCATATCAT TGAGTTAATC 
TCCCCCAACT CCAATCCTTA CAGCACCTTC CAGGTGGATA TAATAATTGA CATACGACCT 
GCTCGAGAGG ATCCTGAGGT GGTCAAAAAC CTCGTCCTGA TCTTGAAGTG CAAAAAATCT 
GTCAACTGGG TGATCAAGTC TTTTGACGTC AAGGGAAACT TGAAAGTTAT TGCTCCTGAC 
AGTATTGGCT TTGGAAAAGA GAGTGAACGA TCCATGACAG TGACCAAATT GGTAAGAAAT 
GACATCCCTT CCACCCAAGA GAATCTGATG AAGTGGGCAT TGGACAATGG CTACAGCCCA 
GTGACGTCAT ACACCATAGC TCCTGTGGCC AATAGATTTC ATCTTCGGCT TGAGAACAAC 
GAGGAGATGA GAGATGAGGA AGTCCACACC ATTCCTCCTG AGCTTCGGAT CCTGCTGGGC 
CCTGACCACC TGCCTGCCCT GGACAGCCCA TCCTTCCAAG GGGAAATCCC AAATGGAGGT 
TTCCCCTTCC CATTCCCGGA TATCCCCAGG AGAGGCTGGA AGGAGGGAGA AGATAGGATC 
CCCCGGCCAA AGGAACCCAT CATTCCCAGA GTTCAATTGC TTCCAGACCA CAGAGAGCCA 
GAAGAAGTGC AAGGGGGCGT GAATATCGCC CTGTCAGTCA AATGTGACAA TGAAAAGATG 
GTGGTAGCTG TAGACAAAGA TTCTTTCCAG ACCAATGGCT ACTCGGGGAT GGAGCTCACC 
CTGTTGGATC CTTCCTGCAA AGCCAAGATG AATGGTACCC ACTTTGTACT GGAGTCTCCG 
CTGAATGGCT GTGGTACTAG ACATAGGAGG TCAGCCCCAG ATGGTGTGGT TTACTATAAC 
TCTATTGTGG TGCAGGCTCC ATCCCCTGGG GATAGCAGTG GCTGGCCAGA CGGCTACGAA 
GATTTGGAGT CGGGTGATAA TGGATTTCCT GGAGACACAG ATGAAGGAGA AACTGCCCCC 
CTGAGCCGTG CTGGAGTGGT AGTGTTTAAC TGCAGCTTGC GGCAGCTGAG GAGTCCCAGT 
GGCTTCCAGG ACCAGCTCGA TGGAAATGCT ACCTTCAACA TGGAGCTGTA TAACACAGAC 
CTCTTTCTGG TGCCCTCCCC AGGGGTCTTC TCTGTGGCAG AGAATGAGCA TGTATATGTT 
GAGGTGTCTG TCACTAAGGC TGACCAAGAT CTGGGATTTG CCATCCAAAC CTGCTTTATC 
TCTCCATACT CAAACCCAGA CAGAATGTCT GATTACACCA TCATCGAGAA CATCTGTCCG 
AAGGATGACT CTGTGAAGTT CTACAGCTCC AAGAGAGTGC ACTTCCCCAT CCCACATGCT 
GAAGTGGACA AGAAGCGGTT CAGCTTTGTG TTCAAGTCCG TGTTCAACAC CTCCCTGCTC 
TTCCTGCACT GCGAGCTGAC GCTGTGCTCT AGGAAGAAGG GCTCCCAGAA GCTGCCAAAG 
TGTGTGACTC CTGACGACGC CTGCACCTCT CTAGATGCCA CCATGATCTG GACCATGATG 
CAGAATAAGA AGACATTCAC CAAGCCCCTG GCCGTGGTCC TCCAAGTAGA TTATAAAGAA 
AATGTTCCAA ACATGAAGGA GTCCAGTCCG GTTCCTCCTC CTCCACAGAT TTTCCACGGC 
CTGGACACGC TCACCGTGAT GGGCATTGCG TTTGCAGCAT TTGTGATCGG AGCACTCCTG 
ACGGGGGCCT TGTGGTATAT CTACTCCCAC ACAGGGGAGA CGGCACGAAG GCAGCAAGTC 
CCTACCTCGC CACCAGCCTC GGAGAACAGC AGCGCAGCCC ACAGCATAGG GAGCACTCAG 
AGCACTCCCT GCTCTAGCAG CAGCACGGCC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

T?RIII is induced by TCR signaling and downregulated in FoxP3
Biochemical and biophysical research communications494(1-2)82-87(2017 12)
Ortega-Francisco S,de la Fuente-Granada M,Alvarez Salazar EK,Bola?os-Castro LA,Fonseca-Camarillo G,Olguin-Alor R,Alem?n-Muench GR,L?pez-Casillas F,Raman C,Garc?a-Zepeda EA,Soldevila G

Transforming Growth Factor-? Receptor III is a Potential Regulator of Ischemia-Induced Cardiomyocyte Apoptosis.
Journal of the American Heart Association6(6)(2017 May)
Sun F,Li X,Duan WQ,Tian W,Gao M,Yang J,Wu XY,Huang D,Xia W,Han YN,Wang JX,Liu YX,Dong CJ,Zhao D,Ban T,Chu WF

Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGF?R3 In Vitro.
PloS one11(8)e0159710(2016)
DeLaughter DM,Clark CR,Christodoulou DC,Seidman CE,Baldwin HS,Seidman JG,Barnett JV

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Tgfbr3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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