Alyref cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Alyref
Entrez Gene ID	21681
Full Name	Aly/REF export factor
Synonyms	ALY,REF1,Refbp1,Thoc4
General protein information	Preferred Names Aly/REF export factor Names THO complex subunit 4 REF1-I RNA and export factor binding protein 1 THO complex 4 Tcra enhancer-binding factor interacting protein 1 ally of AML-1 and LEF-1 tho4 transcriptional coactivator Aly/REF
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 E2

mRNA and Protein(s)

mRNA	Protein	Name
NM_011568.1	NP_035698.1	THO complex subunit 4

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006733	XP_309011.3
Oryza sativa (rice)	Os03g0278300	NP_001049725.2
Pan troglodytes (chimpanzee)	THOC4	XP_001165277.2
Gallus gallus (chicken)	ALYREF	NP_001264836.1
Arabidopsis thaliana (thale cress)	AT5G02530	NP_001190207.1
Danio rerio (zebrafish)	alyref	NP_001098578.1
Drosophila melanogaster (fruit fly)	Ref1	NP_651968.1
Mus musculus (house mouse)	Alyref	NP_035698.1
Arabidopsis thaliana (thale cress)	AT5G59950	NP_001190572.1
Xenopus tropicalis (tropical clawed frog)	alyref	NP_001017027.1

Gene Ontology
Bibliography

Related articles in PubMed

VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease.
Guo X, Sun X, Hu D, Wang YJ, Fujioka H, Vyas R, Chakrapani S, Joshi AU, Luo Y, Mochly-Rosen D, Qi X
Nature communications712646(2016 Aug)

The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.
Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H
PloS one8(10)e75754(2013)

Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain.
Hammock EA, Eagleson KL, Barlow S, Earls LR, Miller DM 3rd, Levitt P
Neural development532(2010 Dec)

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Structure of the nuclear factor ALY provides insights into post-transcriptional regulatory and mRNA nuclear export processes.
Title: Structure of the nuclear factor ALY: insights into post-transcriptional regulatory and mRNA nuclear export processes.

The following Alyref gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Alyref cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu14673	NM_011568.1 Latest version!	Mus musculus Aly/REF export factor (Alyref), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Alyref ( NM_011568.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035698.1 Mus musculus Aly/REF export factor (Alyref), mRNA.

Price & Availability↑

CloneID	OMu14673
Clone ID Related Accession (Same CDS sequence)	NM_011568.1
Accession Version	NM_011568.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 768bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-02
Organism	Mus musculus(house mouse)
Product	THO complex subunit 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from U89876.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U89876.1, CB201594.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164139 [ECO:0000348] ##Evidence-Data-END##

ATGGCCGACA AAATGGACAT GTCTTTGGAC GACATCATTA AGCTGAACCG GAGCCAGCGA 
GGAGGCCGCG GCGGGGGCCG GGGTCGCGGC AGGGCCGGCT CCCAGGGCGG CCGCGGCGGC 
GCAGTGCAGG CCGCCGCGCG GGTGAATCGA GGCGGCGGGC CTATGAGGAA CCGGCCCGCC 
ATCGCCCGCG GCGCCGCAGG CGGCGGCAGG AACCGGCCGG CGCCGTACAG CAGACCGAAA 
CAACTTCCCG ACAAATGGCA GCACGACCTC TTCGACAGCG GCTTCGGGGG TGGAGCCGGC 
GTGGAGACCG GCGGGAAGCT GCTGGTGTCC AACCTGGACT TCGGAGTGTC AGATGCTGAT 
ATTCAGGAAC TCTTTGCTGA ATTTGGGACA TTGAAAAAAG CTGCTGTGCA CTATGATCGC 
TCTGGACGAA GTTTAGGGAC AGCAGATGTG CACTTTGAAC GGAAAGCAGA TGCCCTGAAG 
GCTATGAAAC AGTACAATGG TGTCCCTTTG GATGGCCGCC CTATGAACAT CCAGCTTGTC 
ACATCACAGA TTGATACACA GCGAAGACCT GCACAGAGCA TAAACAGAGG CGGCATGACA 
AGAAACCGTG GCTCTGGAGG TTTTGGTGGT GGTGGCACCA GGAGAGGGAC ACGTGGAGGC 
AGCCGGGGAA GAGGTAGAGG CACCGGCAGG AACTCAAAGC AGCAGCTTTC TGCAGAGGAG 
TTGGACGCAC AGCTGGATGC TTACAATGCA AGGATGGACA CCAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035698.1
CDS	28..795
Translation	MADKMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGGRGGAVQAAARVNRGGGPMRNRPAIARGAAGGGRNRPAPYSRPKQLPDKWQHDLFDSGFGGGAGVETGGKLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIDTQRRPAQSINRGGMTRNRGSGGFGGGGTRRGTRGGSRGRGRGTGRNSKQQLSAEELDAQLDAYNARMDTS

Target ORF information:

RefSeq Version	NM_011568.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus Aly/REF export factor (Alyref), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011568.1

ORF Insert Sequence:

ATGGCCGACA AAATGGACAT GTCTTTGGAC GACATCATTA AGCTGAACCG GAGCCAGCGA 
GGAGGCCGCG GCGGGGGCCG GGGTCGCGGC AGGGCCGGCT CCCAGGGCGG CCGCGGCGGC 
GCAGTGCAGG CCGCCGCGCG GGTGAATCGA GGCGGCGGGC CTATGAGGAA CCGGCCCGCC 
ATCGCCCGCG GCGCCGCAGG CGGCGGCAGG AACCGGCCGG CGCCGTACAG CAGACCGAAA 
CAACTTCCCG ACAAATGGCA GCACGACCTC TTCGACAGCG GCTTCGGGGG TGGAGCCGGC 
GTGGAGACCG GCGGGAAGCT GCTGGTGTCC AACCTGGACT TCGGAGTGTC AGATGCTGAT 
ATTCAGGAAC TCTTTGCTGA ATTTGGGACA TTGAAAAAAG CTGCTGTGCA CTATGATCGC 
TCTGGACGAA GTTTAGGGAC AGCAGATGTG CACTTTGAAC GGAAAGCAGA TGCCCTGAAG 
GCTATGAAAC AGTACAATGG TGTCCCTTTG GATGGCCGCC CTATGAACAT CCAGCTTGTC 
ACATCACAGA TTGATACACA GCGAAGACCT GCACAGAGCA TAAACAGAGG CGGCATGACA 
AGAAACCGTG GCTCTGGAGG TTTTGGTGGT GGTGGCACCA GGAGAGGGAC ACGTGGAGGC 
AGCCGGGGAA GAGGTAGAGG CACCGGCAGG AACTCAAAGC AGCAGCTTTC TGCAGAGGAG 
TTGGACGCAC AGCTGGATGC TTACAATGCA AGGATGGACA CCAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease.
Nature communications712646(2016 Aug)
Guo X,Sun X,Hu D,Wang YJ,Fujioka H,Vyas R,Chakrapani S,Joshi AU,Luo Y,Mochly-Rosen D,Qi X

The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.
PloS one8(10)e75754(2013)
Shimizu H,Kubo A,Uchibe K,Hashimoto M,Yokoyama S,Takada S,Mitsuoka K,Asahara H

Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain.
Neural development532(2010 Dec)
Hammock EA,Eagleson KL,Barlow S,Earls LR,Miller DM 3rd,Levitt P

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H

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Alyref cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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