Pla2g4b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pla2g4b
Entrez Gene ID	211429
Full Name	phospholipase A2, group IVB (cytosolic)
Synonyms	A030011C02Rik,Gm1013,cPLA2-beta
General protein information	Preferred Names phospholipase A2, group IVB (cytosolic) Names cytosolic phospholipase A2 beta phospholipase A2 group IVB
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 E5

mRNA and Protein(s)

mRNA	Protein	Name
NM_145378.4	NP_663353.3	cytosolic phospholipase A2 beta

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	PLA2G4B	NP_001191165.1
Rattus norvegicus (Norway rat)	Pla2g4b	NP_001101234.2
Gallus gallus (chicken)	PLA2G4B	XP_004941702.1
Homo sapiens (human)	PLA2G4B	NP_001108105.1
Mus musculus (house mouse)	Pla2g4b	NP_663353.3
Pan troglodytes (chimpanzee)	PLA2G4B	XP_001157544.1
Bos taurus (cattle)	PLA2G4B	NP_001108129.1

Gene Ontology
Bibliography

Related articles in PubMed

Cooperation of TLR2 with MyD88, PI3K, and Rac1 in lipoteichoic acid-induced cPLA2/COX-2-dependent airway inflammatory responses.
Lee IT, Lee CW, Tung WH, Wang SW, Lin CC, Shu JC, Yang CM
The American journal of pathology176(4)1671-84(2010 Apr)

Function, activity, and membrane targeting of cytosolic phospholipase A(2)zeta in mouse lung fibroblasts.
Ghosh M, Loper R, Ghomashchi F, Tucker DE, Bonventre JV, Gelb MH, Leslie CC
The Journal of biological chemistry282(16)11676-86(2007 Apr)

Identification of novel cytosolic phospholipase A(2)s, murine cPLA(2){delta}, {epsilon}, and {zeta}, which form a gene cluster with cPLA(2){beta}.
Ohto T, Uozumi N, Hirabayashi T, Shimizu T
The Journal of biological chemistry280(26)24576-83(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TLR2 cooperates with MyD88, PI3K, and Rac1 in lipoteichoic acid-induced cPLA2/COX-2-dependent airway inflammatory responses
Title: Cooperation of TLR2 with MyD88, PI3K, and Rac1 in lipoteichoic acid-induced cPLA2/COX-2-dependent airway inflammatory responses.

murine cytosolic phospholipases A2 delta, epsilon, and zeta form a gene cluster with cPLA(2)beta
Title: Identification of novel cytosolic phospholipase A(2)s, murine cPLA(2){delta}, {epsilon}, and {zeta}, which form a gene cluster with cPLA(2){beta}.

The following Pla2g4b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pla2g4b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu11474	NM_145378.4 Latest version!	Mus musculus phospholipase A2, group IVB (cytosolic) (Pla2g4b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$468.30 $669.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pla2g4b ( NM_145378.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_663353.3 Mus musculus phospholipase A2, group IVB (cytosolic) (Pla2g4b), mRNA.

Price & Availability↑

CloneID	OMu11474
Clone ID Related Accession (Same CDS sequence)	NM_145378.4
Accession Version	NM_145378.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2376bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Mus musculus(house mouse)
Product	cytosolic phospholipase A2 beta
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK137721.1, DQ888308.1 and AL833774.4. On Oct 22, 2013 this sequence version replaced NM_145378.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849376, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTCTGC AAACCTGCCC AGTCTACATG CAGGCAAAGG TGCCAGAGAC ATGCCTGCTC 
ACTGTACGCG TCCTCCGGGC CAGTGGCTTG CCTTCCAAGG ACCTAGTAAC CTCCTCTGAC 
TGCTATGTGA CTCTGAACCT GCCCACGGCT TCCAGCCACA CGCTCCAGAC ACGCACAGTC 
AAGAACAGCC GAAACCCTGT CTGGAATCAG AACTTCCACT TCCGGATCCA TAGGCAGCTC 
AAGAATGTTA TGGAACTGAA AGTCTTTGAC CATGACCTGG TGACCAGAGA TGACCCAGTA 
TTGTCAGTGC TGTTTGACGT GGGGACCCTG CAAATTGGGA CTCAGCGCCA GAGCTTCTCC 
TTGGGTACTC AGGAGAAAGG GTGCTTAGAA GTTGAGTTTC GGCTACAGAC TCTGACAGAC 
TGTGAGGAAC AGCTCATCAG CAATGGCATC GTGGTGGCCC GGGAACTCTC CTGCTTGCAC 
GTTGAACTGA AGAGGACAGG AGATCCAAAG AGGTCAGAGC GCAAAGTTCA ACTTGTGGTT 
GCTGGGGCCT GTGAGGGCCC ACAGGATGCC TCTGCGGGCA CTGGATCTTT CCACTTCCAT 
TATCCAGCCT GCTGGGAGCA AGAGCTGAAT GTTCATCTGC AGGATGACCC CCATGAGCAG 
CTGAAGGTGC CACTACGAAC TCTACCCTCC TCGCAGCTGG TGAGACTTGT CTTCCCCACG 
TCCCAGGAGC CACTGATGAG GCTGGAACTC AAGAAGGAAG AAGGACCAAA GGAGCTGGCT 
GTGCGGCTGG GCTGTGGGCC CTGCCCTGAG GAACAGGCCT TCCTAAGCAA GAGGAAGCAG 
GTGGTGGCTG CCGCGCTGAA AAAGGCCTTA CAGCTGGACC AAGACCTGCA CGAGGATGAG 
ATCCCCGTGA TTGCCGTGAT GGCCACTGGT GGTGGGATCC GGGCCATGAC GTCTTTGTAT 
GGGCAGCTGG CCGGCCTGCA GGAGCTCGGC CTTCTCGACT GCATCTCCTA TATCACGGGG 
GCTTCAGGAT CCACCTGGGC ACTGGCCAAC CTCTATGAGG ACCCAGAGTG GTCGCAGAAG 
GACCTGGCAG GGCCCACTGA GGTGCTGAAG ACACAGGTGA CAAAGAGCAA GCTGGGTGCG 
TTGGCCCCTA GCCAACTTTG GCGGTACCGG CAAGAGCTGG CTGAGCGTGC TCGCCTGGGC 
CACCCAACCT GCTTCACCAA CTTGTGGGCC CTCATTAATG AGGCCTTGCT GCACGACAAG 
CCCCATGAAC ACAAACTCTC AGATCAACGA GAGGCCCTGA GTCGAGGCCA GAACCCTCTG 
CCTATCTATT GTGCCCTCAA CAGCAAGGAG CAGGGCCTGA GTACCTTTGA CTTTGGGGAG 
TGGTGTGAGT TCTCTCCATA TGAAGTCGGC TTCCCCAAGT ATGGAGCCTT CATCTCCTCC 
GAGCTCTTTG GCTCGGAGTT CTTTATGGGG CGGCTGGTGA AGCAGCTTCC CGAGTCCCGC 
ATCTGCTTCC TGGAAGGCAT CTGGAGCAAT CTGTTTGCGG CCAGCCTCCA AGACAGCTTG 
TACTGGTCCT CAGAACCCAG CCAGTTCTGG GACCGCTGGG CGCAGGATCA GGCCAACCTG 
GACAAAGAGC AGGTCCCCCA TCTGAAGATA GCAGAGCCAC CGACAATGGC TGGCAGGATC 
GCCGAGCTCT TCACTGACCT CCTGACAAAG CGTCCCCTCG CCCACGCCAC CCACAACTTC 
ACGCGAGGCC TCCATTTCCA CAAGGACTAT TTCCAGAACT CTCACTTCTC TGCCTGGAAA 
GCTTCCAAAC TGGACAGGCT CCCCAACCAG CTGACACCCA CTGAGCCCCA CCTCTGCCTC 
CTGGATGTTG GCTATCTCAT CAATACTAGC TGCCCACCCC TCCTGCAGCC AACACGGGAT 
GTGGACCTCA TCTTGTCACT GGACTACAAC CTCTACGGAG CCTTTCAGCA GCTGCAGCTT 
CTGAGCCGGT TCTGCCAGGA GCAGGGCATC CCTTTCCCAT CCATCTCACC CAGCCCCGAG 
GAGCAGCGGC AGCCTCAGGA GTGCCATCTG TTCTGTGACC CAGCCCAGCC CGAAGCCCCG 
GCTGTGCTGC ACTTCCCTTT GGTCAATGAC TCCTTCCAAG ACTACTCTGC CCCTGGGGTG 
CCACGGACAT CGGAGGAGAA GGCAGCTGGG GAGGTGAATC TGTCTTCTTC TGACTCCCCA 
TACCACTACA CAAAAGTGAC CTACAGCCAG GAAGATGTGG ACAAGCTGTT ACGGCTGACG 
CATTACAACA TCTGCAACAA CCAGGATCGG CTGCGGGAGG CCATGCACCA GGCCGTGCAG 
CGGCGGAGAA AGCGCAAACA GTTTAGGCCG GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_663353.3
CDS	66..2441
Translation	MALQTCPVYMQAKVPETCLLTVRVLRASGLPSKDLVTSSDCYVTLNLPTASSHTLQTRTVKNSRNPVWNQNFHFRIHRQLKNVMELKVFDHDLVTRDDPVLSVLFDVGTLQIGTQRQSFSLGTQEKGCLEVEFRLQTLTDCEEQLISNGIVVARELSCLHVELKRTGDPKRSERKVQLVVAGACEGPQDASAGTGSFHFHYPACWEQELNVHLQDDPHEQLKVPLRTLPSSQLVRLVFPTSQEPLMRLELKKEEGPKELAVRLGCGPCPEEQAFLSKRKQVVAAALKKALQLDQDLHEDEIPVIAVMATGGGIRAMTSLYGQLAGLQELGLLDCISYITGASGSTWALANLYEDPEWSQKDLAGPTEVLKTQVTKSKLGALAPSQLWRYRQELAERARLGHPTCFTNLWALINEALLHDKPHEHKLSDQREALSRGQNPLPIYCALNSKEQGLSTFDFGEWCEFSPYEVGFPKYGAFISSELFGSEFFMGRLVKQLPESRICFLEGIWSNLFAASLQDSLYWSSEPSQFWDRWAQDQANLDKEQVPHLKIAEPPTMAGRIAELFTDLLTKRPLAHATHNFTRGLHFHKDYFQNSHFSAWKASKLDRLPNQLTPTEPHLCLLDVGYLINTSCPPLLQPTRDVDLILSLDYNLYGAFQQLQLLSRFCQEQGIPFPSISPSPEEQRQPQECHLFCDPAQPEAPAVLHFPLVNDSFQDYSAPGVPRTSEEKAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLRLTHYNICNNQDRLREAMHQAVQRRRKRKQFRPE

Target ORF information:

RefSeq Version	NM_145378.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus phospholipase A2, group IVB (cytosolic) (Pla2g4b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145378.4

ORF Insert Sequence:

ATGGCTCTGC AAACCTGCCC AGTCTACATG CAGGCAAAGG TGCCAGAGAC ATGCCTGCTC 
ACTGTACGCG TCCTCCGGGC CAGTGGCTTG CCTTCCAAGG ACCTAGTAAC CTCCTCTGAC 
TGCTATGTGA CTCTGAACCT GCCCACGGCT TCCAGCCACA CGCTCCAGAC ACGCACAGTC 
AAGAACAGCC GAAACCCTGT CTGGAATCAG AACTTCCACT TCCGGATCCA TAGGCAGCTC 
AAGAATGTTA TGGAACTGAA AGTCTTTGAC CATGACCTGG TGACCAGAGA TGACCCAGTA 
TTGTCAGTGC TGTTTGACGT GGGGACCCTG CAAATTGGGA CTCAGCGCCA GAGCTTCTCC 
TTGGGTACTC AGGAGAAAGG GTGCTTAGAA GTTGAGTTTC GGCTACAGAC TCTGACAGAC 
TGTGAGGAAC AGCTCATCAG CAATGGCATC GTGGTGGCCC GGGAACTCTC CTGCTTGCAC 
GTTGAACTGA AGAGGACAGG AGATCCAAAG AGGTCAGAGC GCAAAGTTCA ACTTGTGGTT 
GCTGGGGCCT GTGAGGGCCC ACAGGATGCC TCTGCGGGCA CTGGATCTTT CCACTTCCAT 
TATCCAGCCT GCTGGGAGCA AGAGCTGAAT GTTCATCTGC AGGATGACCC CCATGAGCAG 
CTGAAGGTGC CACTACGAAC TCTACCCTCC TCGCAGCTGG TGAGACTTGT CTTCCCCACG 
TCCCAGGAGC CACTGATGAG GCTGGAACTC AAGAAGGAAG AAGGACCAAA GGAGCTGGCT 
GTGCGGCTGG GCTGTGGGCC CTGCCCTGAG GAACAGGCCT TCCTAAGCAA GAGGAAGCAG 
GTGGTGGCTG CCGCGCTGAA AAAGGCCTTA CAGCTGGACC AAGACCTGCA CGAGGATGAG 
ATCCCCGTGA TTGCCGTGAT GGCCACTGGT GGTGGGATCC GGGCCATGAC GTCTTTGTAT 
GGGCAGCTGG CCGGCCTGCA GGAGCTCGGC CTTCTCGACT GCATCTCCTA TATCACGGGG 
GCTTCAGGAT CCACCTGGGC ACTGGCCAAC CTCTATGAGG ACCCAGAGTG GTCGCAGAAG 
GACCTGGCAG GGCCCACTGA GGTGCTGAAG ACACAGGTGA CAAAGAGCAA GCTGGGTGCG 
TTGGCCCCTA GCCAACTTTG GCGGTACCGG CAAGAGCTGG CTGAGCGTGC TCGCCTGGGC 
CACCCAACCT GCTTCACCAA CTTGTGGGCC CTCATTAATG AGGCCTTGCT GCACGACAAG 
CCCCATGAAC ACAAACTCTC AGATCAACGA GAGGCCCTGA GTCGAGGCCA GAACCCTCTG 
CCTATCTATT GTGCCCTCAA CAGCAAGGAG CAGGGCCTGA GTACCTTTGA CTTTGGGGAG 
TGGTGTGAGT TCTCTCCATA TGAAGTCGGC TTCCCCAAGT ATGGAGCCTT CATCTCCTCC 
GAGCTCTTTG GCTCGGAGTT CTTTATGGGG CGGCTGGTGA AGCAGCTTCC CGAGTCCCGC 
ATCTGCTTCC TGGAAGGCAT CTGGAGCAAT CTGTTTGCGG CCAGCCTCCA AGACAGCTTG 
TACTGGTCCT CAGAACCCAG CCAGTTCTGG GACCGCTGGG CGCAGGATCA GGCCAACCTG 
GACAAAGAGC AGGTCCCCCA TCTGAAGATA GCAGAGCCAC CGACAATGGC TGGCAGGATC 
GCCGAGCTCT TCACTGACCT CCTGACAAAG CGTCCCCTCG CCCACGCCAC CCACAACTTC 
ACGCGAGGCC TCCATTTCCA CAAGGACTAT TTCCAGAACT CTCACTTCTC TGCCTGGAAA 
GCTTCCAAAC TGGACAGGCT CCCCAACCAG CTGACACCCA CTGAGCCCCA CCTCTGCCTC 
CTGGATGTTG GCTATCTCAT CAATACTAGC TGCCCACCCC TCCTGCAGCC AACACGGGAT 
GTGGACCTCA TCTTGTCACT GGACTACAAC CTCTACGGAG CCTTTCAGCA GCTGCAGCTT 
CTGAGCCGGT TCTGCCAGGA GCAGGGCATC CCTTTCCCAT CCATCTCACC CAGCCCCGAG 
GAGCAGCGGC AGCCTCAGGA GTGCCATCTG TTCTGTGACC CAGCCCAGCC CGAAGCCCCG 
GCTGTGCTGC ACTTCCCTTT GGTCAATGAC TCCTTCCAAG ACTACTCTGC CCCTGGGGTG 
CCACGGACAT CGGAGGAGAA GGCAGCTGGG GAGGTGAATC TGTCTTCTTC TGACTCCCCA 
TACCACTACA CAAAAGTGAC CTACAGCCAG GAAGATGTGG ACAAGCTGTT ACGGCTGACG 
CATTACAACA TCTGCAACAA CCAGGATCGG CTGCGGGAGG CCATGCACCA GGCCGTGCAG 
CGGCGGAGAA AGCGCAAACA GTTTAGGCCG GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cooperation of TLR2 with MyD88, PI3K, and Rac1 in lipoteichoic acid-induced cPLA2/COX-2-dependent airway inflammatory responses.
The American journal of pathology176(4)1671-84(2010 Apr)
Lee IT,Lee CW,Tung WH,Wang SW,Lin CC,Shu JC,Yang CM

Function, activity, and membrane targeting of cytosolic phospholipase A(2)zeta in mouse lung fibroblasts.
The Journal of biological chemistry282(16)11676-86(2007 Apr)
Ghosh M,Loper R,Ghomashchi F,Tucker DE,Bonventre JV,Gelb MH,Leslie CC

Identification of novel cytosolic phospholipase A(2)s, murine cPLA(2){delta}, {epsilon}, and {zeta}, which form a gene cluster with cPLA(2){beta}.
The Journal of biological chemistry280(26)24576-83(2005 Jul)
Ohto T,Uozumi N,Hirabayashi T,Shimizu T

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Pla2g4b cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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