Brcc3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Brcc3
Entrez Gene ID	210766
Full Name	BRCA1/BRCA2-containing complex, subunit 3
Synonyms	C6.1A
General protein information	Preferred Names BRCA1/BRCA2-containing complex, subunit 3 Names lys-63-specific deubiquitinase BRCC36 6.1A protein BRCA1-A complex subunit BRCC36 BRCA1/BRCA2-containing complex subunit 36 BRISC complex subunit BRCC36
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X\|X A7.3

mRNA and Protein(s)

mRNA	Protein	Name
XM_030251295.1	XP_030107155.1	lys-63-specific deubiquitinase BRCC36 isoform X1
NM_001166459.1	NP_001159931.1	lys-63-specific deubiquitinase BRCC36
XM_011247554.2	XP_011245856.1	lys-63-specific deubiquitinase BRCC36 isoform X1
XM_011247554.1	XP_011245856.1	lys-63-specific deubiquitinase BRCC36 isoform X1
NM_145956.4	NP_666068.1	lys-63-specific deubiquitinase BRCC36
NM_001358736.1	NP_001345665.1	lys-63-specific deubiquitinase BRCC36
NM_001358737.1	NP_001345666.1	lys-63-specific deubiquitinase BRCC36
NM_001166457.1	NP_001159929.1	lys-63-specific deubiquitinase BRCC36

Pathways from BioSystems

Homologies

Homo sapiens (human)	BRCC3	NP_077308.1
Pan troglodytes (chimpanzee)	BRCC3	XP_003317841.1
Xenopus tropicalis (tropical clawed frog)	brcc3	NP_001016457.1
Bos taurus (cattle)	BRCC3	NP_001069258.1
Rattus norvegicus (Norway rat)	Brcc3	NP_001120772.1
Arabidopsis thaliana (thale cress)	AT1G80210	NP_178138.2
Oryza sativa (rice)	Os05g0542600	NP_001056196.1
Canis lupus familiaris (dog)	BRCC3	XP_855467.3
Mus musculus (house mouse)	Brcc3	NP_001159931.1
Gallus gallus (chicken)	BRCC3	XP_420195.3
Arabidopsis thaliana (thale cress)	AT3G06820	NP_001078118.1

Gene Ontology
Bibliography

Related articles in PubMed

The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells.
Yan K, Li L, Wang X, Hong R, Zhang Y, Yang H, Lin M, Zhang S, He Q, Zheng D, Tang J, Yin Y, Shao G
The Journal of cell biology210(2)209-24(2015 Jul)

Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity.
Py BF, Kim MS, Vakifahmetoglu-Norberg H, Yuan J
Molecular cell49(2)331-8(2013 Jan)

Loss of GGN leads to pre-implantation embryonic lethality and compromised male meiotic DNA double strand break repair in the mouse.
Jamsai D, O'Connor AE, Deboer KD, Clark BJ, Smith SJ, Browne CM, Bensley JG, Merriman JA, Yuen WS, Koopman P, Jones KT, O'Bryan MK
PloS one8(2)e56955(2013)

ATF4 interacts with Abro1/KIAA0157 scaffold protein and participates in a cytoprotective pathway.
Ambivero CT, Cilenti L, Zervos AS
Biochimica et biophysica acta1823(12)2149-56(2012 Dec)

Identification of genes differentially expressed in mouse fetuses from streptozotocin-induced diabetic pregnancy by cDNA subtraction.
Sato N, Sugimura Y, Hayashi Y, Murase T, Kanou Y, Kikkawa F, Murata Y
Endocrine journal55(2)317-23(2008 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The deubiquitinating enzyme, BRCC3, is a critical regulator of NLRP3 activity by promoting its deubiquitination.
Title: Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity.

The following Brcc3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Brcc3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu10439	NM_001166457.1 Latest version!	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu10439	NM_001358736.1 Latest version!	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu10439	NM_001166459.1 Latest version!	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu10439	NM_145956.4 Latest version!	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu10439	NM_001358737.1 Latest version!	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu10439	XM_030251295.1 Latest version!	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu10439	XM_011247554.2 Latest version!	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
View Old Accession Versions >>
OMu10439	XM_011247554.1	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Brcc3 ( NM_001166459.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001159931.1 Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu10439
Clone ID Related Accession (Same CDS sequence)	XM_030251295.1 , NM_001166459.1 , XM_011247554.2 , XM_011247554.1 , NM_145956.4 , NM_001358736.1 , NM_001358737.1 , NM_001166457.1
Accession Version	NM_001166459.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	lys-63-specific deubiquitinase BRCC36
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL671860.6, AK011876.1 and CD774860.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK011876.1, SRR1660819.208485.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159931.1
CDS	92..967
Translation	MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDIRSDSKFTYTGTEMRTVQEKMDTIRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSEYERIEIPIHIVPHITIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLQELQQEKEELMEELSSLE

Target ORF information:

RefSeq Version	NM_001166459.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166459.1

ORF Insert Sequence:

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Brcc3 ( NM_145956.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_666068.1 Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu10439
Clone ID Related Accession (Same CDS sequence)	XM_030251295.1 , NM_001166459.1 , XM_011247554.2 , XM_011247554.1 , NM_145956.4 , NM_001358736.1 , NM_001358737.1 , NM_001166457.1
Accession Version	NM_145956.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	lys-63-specific deubiquitinase BRCC36
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL671860.6, AK030736.1 and BC048179.1. On Oct 24, 2009 this sequence version replaced NM_145956.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK030736.1, SRR1660817.217674.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_666068.1
CDS	92..967
Translation	MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDIRSDSKFTYTGTEMRTVQEKMDTIRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSEYERIEIPIHIVPHITIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLQELQQEKEELMEELSSLE

Target ORF information:

RefSeq Version	NM_145956.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145956.4

ORF Insert Sequence:

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Brcc3 ( NM_001358736.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001345665.1 Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu10439
Clone ID Related Accession (Same CDS sequence)	XM_030251295.1 , NM_001166459.1 , XM_011247554.2 , XM_011247554.1 , NM_145956.4 , NM_001358736.1 , NM_001358737.1 , NM_001166457.1
Accession Version	NM_001358736.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	lys-63-specific deubiquitinase BRCC36
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL671860.6 and CD774860.1. On Dec 7, 2017 this sequence version replaced XM_011247554.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: DV054158.1, DV044228.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001345665.1
CDS	92..967
Translation	MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDIRSDSKFTYTGTEMRTVQEKMDTIRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSEYERIEIPIHIVPHITIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLQELQQEKEELMEELSSLE

Target ORF information:

RefSeq Version	NM_001358736.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001358736.1

ORF Insert Sequence:

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Brcc3 ( NM_001358737.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001345666.1 Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OMu10439
Clone ID Related Accession (Same CDS sequence)	XM_030251295.1 , NM_001166459.1 , XM_011247554.2 , XM_011247554.1 , NM_145956.4 , NM_001358736.1 , NM_001358737.1 , NM_001166457.1
Accession Version	NM_001358737.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Mus musculus(house mouse)
Product	lys-63-specific deubiquitinase BRCC36
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL671860.6 and BC048179.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK038919.1, DV060546.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001345666.1
CDS	92..967
Translation	MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDIRSDSKFTYTGTEMRTVQEKMDTIRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSEYERIEIPIHIVPHITIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLQELQQEKEELMEELSSLE

Target ORF information:

RefSeq Version	NM_001358737.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001358737.1

ORF Insert Sequence:

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Brcc3 ( NM_001166457.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001159929.1 Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu10439
Clone ID Related Accession (Same CDS sequence)	XM_030251295.1 , NM_001166459.1 , XM_011247554.2 , XM_011247554.1 , NM_145956.4 , NM_001358736.1 , NM_001358737.1 , NM_001166457.1
Accession Version	NM_001166457.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	lys-63-specific deubiquitinase BRCC36
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL671860.6, AK149844.1 and BC048179.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC048179.1, SRR1660821.164536.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159929.1
CDS	92..967
Translation	MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDIRSDSKFTYTGTEMRTVQEKMDTIRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSEYERIEIPIHIVPHITIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLQELQQEKEELMEELSSLE

Target ORF information:

RefSeq Version	NM_001166457.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166457.1

ORF Insert Sequence:

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Brcc3 ( XM_030251295.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030107155.1 Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu10439
Clone ID Related Accession (Same CDS sequence)	XM_030251295.1 , NM_001166459.1 , XM_011247554.2 , XM_011247554.1 , NM_145956.4 , NM_001358736.1 , NM_001358737.1 , NM_001166457.1
Accession Version	XM_030251295.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	lys-63-specific deubiquitinase BRCC36 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030107155.1
CDS	92..967
Translation	MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDIRSDSKFTYTGTEMRTVQEKMDTIRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSEYERIEIPIHIVPHITIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLQELQQEKEELMEELSSLE

Target ORF information:

RefSeq Version	XM_030251295.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030251295.1

ORF Insert Sequence:

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Brcc3 ( XM_011247554.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011245856.1 Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu10439
Clone ID Related Accession (Same CDS sequence)	XM_030251295.1 , NM_001166459.1 , XM_011247554.2 , XM_011247554.1 , NM_145956.4 , NM_001358736.1 , NM_001358737.1 , NM_001166457.1
Accession Version	XM_011247554.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	lys-63-specific deubiquitinase BRCC36 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011247554.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011245856.1
CDS	97..972
Translation	MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDIRSDSKFTYTGTEMRTVQEKMDTIRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSEYERIEIPIHIVPHITIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLQELQQEKEELMEELSSLE

Target ORF information:

RefSeq Version	XM_011247554.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011247554.2

ORF Insert Sequence:

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Brcc3 ( XM_011247554.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011245856.1 Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu10439
Clone ID Related Accession (Same CDS sequence)	XM_030251295.1 , NM_001166459.1 , XM_011247554.2 , XM_011247554.1 , NM_145956.4 , NM_001358736.1 , NM_001358737.1 , NM_001166457.1
Accession Version	XM_011247554.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	lys-63-specific deubiquitinase BRCC36 isoform X1
Comment

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011245856.1
Translation	MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDIRSDSKFTYTGTEMRTVQEKMDTIRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSEYERIEIPIHIVPHITIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLQELQQEKEELMEELSSLE

Target ORF information:

RefSeq Version	XM_011247554.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011247554.1

ORF Insert Sequence:

ATGGCGGTGC AGGTGGTGCA AGCTGTGCAG GCGGTTCATC TTGAGTCTGA CGCTTTCCTA 
GTTTGTCTCA ACCATGCTCT GAGCACAGAA AAGGAGGAAG TGATGGGTCT GTGTATAGGG 
GAGTTGAATG ATGACATAAG GAGTGACTCC AAATTTACAT ACACTGGAAC GGAAATGCGC 
ACAGTCCAAG AAAAGATGGA TACCATCAGA ATTGTTCATA TCCATTCTGT CATCATCTTG 
CGGCGTTCTG ACAAGAGAAA GGACCGTGTA GAAATTTCTC CAGAGCAGCT GTCTGCAGCT 
TCAACAGAGG CAGAAAGGTT GGCTGAACTA ACAGGTCGTC CCATGAGAGT TGTTGGCTGG 
TATCATTCCC ACCCTCATAT AACTGTTTGG CCTTCACATG TTGATGTTCG TACACAAGCC 
ATGTACCAAA TGATGGATCA AGGCTTTGTA GGACTTATTT TTTCCTGTTT CATAGAAGAC 
AAAAACACAA AGACTGGCCG GGTACTCTAT ACTTGCTTCC AATCCATACA AGCCCAAAAA 
AGCTCAGAGT ATGAGAGAAT TGAAATCCCA ATCCATATTG TACCTCATAT CACTATTGGG 
AAAGTATGCC TTGAATCTGC AGTAGAGCTG CCAAAAATCC TGTGTCAGGA AGAACAGGAT 
GCATATAGAA GGATTCACAG CCTTACACAT CTGGACTCAG TGACCAAGAT CCATAATGGC 
TCAGTATTTA CCAAGAATTT GTGCAGTCAG ATGTCAGCAG TCAGTGGGCC TCTACTGCAG 
TGGTTGGAAG ACAGATTGGA GCAAAACCAG CAGCATTTGC AGGAGTTGCA ACAAGAAAAG 
GAAGAGCTTA TGGAAGAGCT GTCTTCCCTA GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells.
The Journal of cell biology210(2)209-24(2015 Jul)
Yan K,Li L,Wang X,Hong R,Zhang Y,Yang H,Lin M,Zhang S,He Q,Zheng D,Tang J,Yin Y,Shao G

Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity.
Molecular cell49(2)331-8(2013 Jan)
Py BF,Kim MS,Vakifahmetoglu-Norberg H,Yuan J

Loss of GGN leads to pre-implantation embryonic lethality and compromised male meiotic DNA double strand break repair in the mouse.
PloS one8(2)e56955(2013)
Jamsai D,O'Connor AE,Deboer KD,Clark BJ,Smith SJ,Browne CM,Bensley JG,Merriman JA,Yuen WS,Koopman P,Jones KT,O'Bryan MK

ATF4 interacts with Abro1/KIAA0157 scaffold protein and participates in a cytoprotective pathway.
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Identification of genes differentially expressed in mouse fetuses from streptozotocin-induced diabetic pregnancy by cDNA subtraction.
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Brcc3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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ORF Insert Sequence:

Target ORF information:

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ORF Insert Sequence:

Target ORF information:

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ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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