The following Serpina1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Serpina1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu05265 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001252569.1 | |
| Accession Version | NM_001252569.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1311bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-23 | |
| Organism | Mus musculus(house mouse) | |
| Product | alpha-1-antitrypsin 1-1 isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC134902.7 and AC098741.2. Transcript Variant: This variant (2) has an additional exon in the 5' region, which includes an upstream in-frame AUG start codon, compared to variant 1. The resulting isoform (2) has a longer N-terminus, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849386, SAMN01164134 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTACTGTG CAATCCGTGT TCGGCTCTCC AGATTATTTA CAGTGAAAGG GCAGAAAGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001239498.1 |
| CDS | 249..1559 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001252569.1 |
1 | ATGTACTGTG CAATCCGTGT TCGGCTCTCC AGATTATTTA CAGTGAAAGG GCAGAAAGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu03778 | |
| Clone ID Related Accession (Same CDS sequence) | NM_009243.4 | |
| Accession Version | NM_009243.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1242bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-27 | |
| Organism | Mus musculus(house mouse) | |
| Product | alpha-1-antitrypsin 1-1 isoform 1 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC134902.7, AK146619.1, W82055.1 and CJ238440.1. On Nov 19, 2011 this sequence version replaced NM_009243.3. Transcript Variant: This variant (1) is the predominant transcript and encodes the shorter isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M75721.1, AK146619.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGACTCCCT CCATCTCATG GGGTCTACTG CTTCTGGCAG GCCTGTGTTG CCTGGTCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_033269.1 |
| CDS | 103..1344 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_009243.4 |
1 | ATGACTCCCT CCATCTCATG GGGTCTACTG CTTCTGGCAG GCCTGTGTTG CCTGGTCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Ubiquitin ligase SYVN1/HRD1 facilitates degradation of the SERPINA1 Z variant/?-1-antitrypsin Z variant via SQSTM1/p62-dependent selective autophagy. |
Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. |
Novel RNA-binding activity of NQO1 promotes SERPINA1 mRNA translation. |
Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus. |
FBG1 Is the Final Arbitrator of A1AT-Z Degradation. |
