The following Sos2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sos2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu21540 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001135559.1 | |
| Accession Version | NM_001135559.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3999bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-13 | |
| Organism | Mus musculus(house mouse) | |
| Product | son of sevenless homolog 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC141560.4, AC133949.4 and AC153658.4. On or before Oct 3, 2008 this sequence version replaced XM_916574.3, XM_127051.8. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164139 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCAGCAGG CGCCGCAGCC CTACGAGTTC TTCAGCGAAG AAAACAGCCC GAAATGGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001129031.1 |
| CDS | 252..4250 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001135559.1 |
1 | ATGCAGCAGG CGCCGCAGCC CTACGAGTTC TTCAGCGAAG AAAACAGCCC GAAATGGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu47691 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006515635.1 | |
| Accession Version | XM_006515635.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4002bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | son of sevenless homolog 2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCAGCAGG CGCCGCAGCC CTACGAGTTC TTCAGCGAAG AAAACAGCCC GAAATGGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006515698.1 |
| CDS | 235..4236 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006515635.1 |
1 | ATGCAGCAGG CGCCGCAGCC CTACGAGTTC TTCAGCGAAG AAAACAGCCC GAAATGGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Absence of both Sos-1 and Sos-2 in peripheral CD4(+) T?cells leads to PI3K pathway activation and defects in migration. |
Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival. |
Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate. |
