Snrpc cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Snrpc
Entrez Gene ID	20630
Full Name	U1 small nuclear ribonucleoprotein C
Synonyms	Snrp1c,U1-C,U1C
General protein information	Preferred Names U1 small nuclear ribonucleoprotein C Names U1 small nuclear ribonucleoprotein C U1 small nuclear ribonucleoprotein 1C U1 snRNP C U1 snRNP protein C
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17\|17 A3.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_011432.2	NP_035562.1	U1 small nuclear ribonucleoprotein C
XM_030249614.1	XP_030105474.1	U1 small nuclear ribonucleoprotein C isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SNRPC	NP_001069802.1
Mus musculus (house mouse)	Snrpc	NP_035562.1
Rattus norvegicus (Norway rat)	Snrpc	NP_001257969.1
Xenopus tropicalis (tropical clawed frog)	snrpc	NP_001016598.1
	LOC706270	XP_001101394.1
Canis lupus familiaris (dog)	SNRPC	XP_532115.3
Danio rerio (zebrafish)	snrpc	NP_775358.1

Gene Ontology
Bibliography

Related articles in PubMed

ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.
Sun S, Ling SC, Qiu J, Albuquerque CP, Zhou Y, Tokunaga S, Li H, Qiu H, Bui A, Yeo GW, Huang EJ, Eggan K, Zhou H, Fu XD, Lagier-Tourenne C, Cleveland DW
Nature communications66171(2015 Jan)

RBFOX2 promotes protein 4.1R exon 16 selection via U1 snRNP recruitment.
Huang SC, Ou AC, Park J, Yu F, Yu B, Lee A, Yang G, Zhou A, Benz EJ Jr
Molecular and cellular biology32(2)513-26(2012 Jan)

WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif.
Bedford MT, Reed R, Leder P
Proceedings of the National Academy of Sciences of the United States of America95(18)10602-7(1998 Sep)

Molecular cloning and developmental expression of a small ribonuclear protein in the mouse testis.
Morales CR, Leyne M, el-Alfy M, Oko R
Molecular reproduction and development46(4)459-70(1997 Apr)

Cloning and characterization of two processed pseudogenes and the cDNA for the murine U1 snRNP-specific protein C.
Nelissen RL, Gunnewiek JM, Lambermon MH, Van Venrooij WJ
Gene184(2)273-8(1997 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these studies establish potentially converging disease mechanisms in amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy, with ALS-causative mutants acquiring properties representing both gain and loss of function.
Title: ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.

The following Snrpc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Snrpc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu08159	NM_011432.2 Latest version!	Mus musculus U1 small nuclear ribonucleoprotein C (Snrpc), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OMu87141	XM_030249614.1 Latest version!	Mus musculus U1 small nuclear ribonucleoprotein C (Snrpc), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Snrpc ( NM_011432.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035562.1 Mus musculus U1 small nuclear ribonucleoprotein C (Snrpc), mRNA.

Price & Availability↑

CloneID	OMu08159
Clone ID Related Accession (Same CDS sequence)	NM_011432.2
Accession Version	NM_011432.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	U1 small nuclear ribonucleoprotein C
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ085691.1, AK137213.1 and AI851507.1. On Feb 8, 2006 this sequence version replaced NM_011432.1. ##Evidence-Data-START## Transcript exon combination :: CF583677.1, CF583678.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCCCAAGT TTTATTGTGA CTACTGTGAT ACGTATCTTA CCCACGATTC TCCATCTGTG 
AGGAAGACAC ACTGCAGTGG TCGGAAACAC AAAGAGAATG TGAAAGACTA TTATCAGAAA 
TGGATGGAAG AGCAGGCCCA GAGCCTGATT GACAAGACAA CGGCTGCATT TCAACAAGGG 
AAGATCCCTC CTGCTCCGTT CTCTGCTCCT CCGCCTGCAG GGGCCATGAT CCCACCTCCC 
CCCAGTCTCC CGGGCCCTCC TCGGCCTGGC ATGATGCCTG CCCCCCACAT GGGAGGCCCT 
CCCATGATGC CAATGATGGG CCCCCCTCCG CCCGGAATGA TGCCCGTGGG ACCAGCTCCT 
GGGATGAGAC CACCCATGGG AGGCCACATG CCCATGATGC CCGGACCTCC CATGATGAGA 
CCTCCTGCCC GCCCTATGAT GGTGCCCACC CGGCCTGGCA TGACCCGGCC AGACAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035562.1
CDS	76..555
Translation	MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPAPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRPGMTRPDR

Target ORF information:

RefSeq Version	NM_011432.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus U1 small nuclear ribonucleoprotein C (Snrpc), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011432.2

ORF Insert Sequence:

ATGCCCAAGT TTTATTGTGA CTACTGTGAT ACGTATCTTA CCCACGATTC TCCATCTGTG 
AGGAAGACAC ACTGCAGTGG TCGGAAACAC AAAGAGAATG TGAAAGACTA TTATCAGAAA 
TGGATGGAAG AGCAGGCCCA GAGCCTGATT GACAAGACAA CGGCTGCATT TCAACAAGGG 
AAGATCCCTC CTGCTCCGTT CTCTGCTCCT CCGCCTGCAG GGGCCATGAT CCCACCTCCC 
CCCAGTCTCC CGGGCCCTCC TCGGCCTGGC ATGATGCCTG CCCCCCACAT GGGAGGCCCT 
CCCATGATGC CAATGATGGG CCCCCCTCCG CCCGGAATGA TGCCCGTGGG ACCAGCTCCT 
GGGATGAGAC CACCCATGGG AGGCCACATG CCCATGATGC CCGGACCTCC CATGATGAGA 
CCTCCTGCCC GCCCTATGAT GGTGCCCACC CGGCCTGGCA TGACCCGGCC AGACAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Snrpc ( XM_030249614.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030105474.1 Mus musculus U1 small nuclear ribonucleoprotein C (Snrpc), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu87141
Clone ID Related Accession (Same CDS sequence)	XM_030249614.1
Accession Version	XM_030249614.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 357bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	U1 small nuclear ribonucleoprotein C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGAGC AGGCCCAGAG CCTGATTGAC AAGACAACGG CTGCATTTCA ACAAGGGAAG 
ATCCCTCCTG CTCCGTTCTC TGCTCCTCCG CCTGCAGGGG CCATGATCCC ACCTCCCCCC 
AGTCTCCCGG GCCCTCCTCG GCCTGGCATG ATGCCTGCCC CCCACATGGG AGGCCCTCCC 
ATGATGCCAA TGATGGGCCC CCCTCCGCCC GGAATGATGC CCGTGGGACC AGCTCCTGGG 
ATGAGACCAC CCATGGGAGG CCACATGCCC ATGATGCCCG GACCTCCCAT GATGAGACCT 
CCTGCCCGCC CTATGATGGT GCCCACCCGG CCTGGCATGA CCCGGCCAGA CAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030105474.1
CDS	294..650
Translation	MEEQAQSLIDKTTAAFQQGKIPPAPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRPGMTRPDR

Target ORF information:

RefSeq Version	XM_030249614.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus U1 small nuclear ribonucleoprotein C (Snrpc), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030249614.1

ORF Insert Sequence:

ATGGAAGAGC AGGCCCAGAG CCTGATTGAC AAGACAACGG CTGCATTTCA ACAAGGGAAG 
ATCCCTCCTG CTCCGTTCTC TGCTCCTCCG CCTGCAGGGG CCATGATCCC ACCTCCCCCC 
AGTCTCCCGG GCCCTCCTCG GCCTGGCATG ATGCCTGCCC CCCACATGGG AGGCCCTCCC 
ATGATGCCAA TGATGGGCCC CCCTCCGCCC GGAATGATGC CCGTGGGACC AGCTCCTGGG 
ATGAGACCAC CCATGGGAGG CCACATGCCC ATGATGCCCG GACCTCCCAT GATGAGACCT 
CCTGCCCGCC CTATGATGGT GCCCACCCGG CCTGGCATGA CCCGGCCAGA CAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.
Nature communications66171(2015 Jan)
Sun S,Ling SC,Qiu J,Albuquerque CP,Zhou Y,Tokunaga S,Li H,Qiu H,Bui A,Yeo GW,Huang EJ,Eggan K,Zhou H,Fu XD,Lagier-Tourenne C,Cleveland DW

RBFOX2 promotes protein 4.1R exon 16 selection via U1 snRNP recruitment.
Molecular and cellular biology32(2)513-26(2012 Jan)
Huang SC,Ou AC,Park J,Yu F,Yu B,Lee A,Yang G,Zhou A,Benz EJ Jr

WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif.
Proceedings of the National Academy of Sciences of the United States of America95(18)10602-7(1998 Sep)
Bedford MT,Reed R,Leder P

Molecular cloning and developmental expression of a small ribonuclear protein in the mouse testis.
Molecular reproduction and development46(4)459-70(1997 Apr)
Morales CR,Leyne M,el-Alfy M,Oko R

Cloning and characterization of two processed pseudogenes and the cDNA for the murine U1 snRNP-specific protein C.
Gene184(2)273-8(1997 Jan)
Nelissen RL,Gunnewiek JM,Lambermon MH,Van Venrooij WJ

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Snrpc cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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