Slc2a2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc2a2
Entrez Gene ID	20526
Full Name	solute carrier family 2 (facilitated glucose transporter), member 2
Synonyms	AI266973,Glut-2,Glut2
General protein information	Preferred Names solute carrier family 2 (facilitated glucose transporter), member 2 Names solute carrier family 2, facilitated glucose transporter member 2 glucose transporter type 2, liver liver-type glucose transporter
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3 A3\|3 12.19 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_031197.2	NP_112474.2	solute carrier family 2, facilitated glucose transporter member 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	SLC2A2	NP_000331.1
Bos taurus (cattle)	SLC2A2	NP_001096692.1
Pan troglodytes (chimpanzee)	SLC2A2	XP_516875.2
Canis lupus familiaris (dog)	SLC2A2	XP_545289.3
Mus musculus (house mouse)	Slc2a2	NP_112474.2
Rattus norvegicus (Norway rat)	Slc2a2	NP_037011.2
	SLC2A2	XP_001088382.1
Xenopus tropicalis (tropical clawed frog)	slc2a2	NP_001011453.1
Gallus gallus (chicken)	SLC2A2	NP_997061.1
Danio rerio (zebrafish)	slc2a2	NP_001036186.1

Gene Ontology
Bibliography

Related articles in PubMed

Transient Impairment of Islet Architectural Development in Pancreas-Specific Bmpr1a-Deleted Prenatal Mice Involves Reduced Expression of E-Cadherin.
Jiang FX, Harrison LC
Stem cells and development26(23)1706-1714(2017 Dec)

Defining a Novel Role for the Pdx1 Transcription Factor in Islet ?-Cell Maturation and Proliferation During Weaning.
Spaeth JM, Gupte M, Perelis M, Yang YP, Cyphert H, Guo S, Liu JH, Guo M, Bass J, Magnuson MA, Wright C, Stein R
Diabetes66(11)2830-2839(2017 11)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the first intracellular loop of GLUT4 contains the retention motif WLGRK, in which W105 plays a prominent role.
Title: The first intracellular loop of GLUT4 contains a retention motif.

hypothalamic arcuate nucleus (Arc)POMC-deficient mice, which develop severe obesity and insulin resistance, unexpectedly exhibit improved glucose tolerance and remain protected from hyperglycemia via decreased renal GLUT2 expression and glycosuria.
Title: Hypothalamic POMC Deficiency Improves Glucose Tolerance Despite Insulin Resistance by Increasing Glycosuria.

analysis of the different diabetic responses to STZ in two different animal strains, which both have similar initial GLUT2 expressions in beta cells
Title: Diabetes-resistant NOR mice are more severely affected by streptozotocin compared to the diabetes-prone NOD mice: correlations with liver and kidney GLUT2 expressions.

The study demonstrates a previously unrecognized mechanism that controls insulin expression through c-Abl-regulated NKx2.2 and GLUT2.
Title: C-Abl inhibitor imatinib enhances insulin production by ? cells: c-Abl negatively regulates insulin production via interfering with the expression of NKx2.2 and GLUT-2.

role of SGLT1 and GLUT2 in intestinal glucose transport and sensing
Title: The role of SGLT1 and GLUT2 in intestinal glucose transport and sensing.

The following Slc2a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc2a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu21691	NM_031197.2 Latest version!	Mus musculus solute carrier family 2 (facilitated glucose transporter), member 2 (Slc2a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc2a2 ( NM_031197.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_112474.2 Mus musculus solute carrier family 2 (facilitated glucose transporter), member 2 (Slc2a2), mRNA.

Price & Availability↑

CloneID	OMu21691
Clone ID Related Accession (Same CDS sequence)	NM_031197.2
Accession Version	NM_031197.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1572bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Mus musculus(house mouse)
Product	solute carrier family 2, facilitated glucose transporter member 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK005068.1, AK165430.1 and AI120520.1. On Jan 16, 2008 this sequence version replaced NM_031197.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK005068.1, AK165430.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849378 [ECO:0000348] ##Evidence-Data-END##

ATGTCAGAAG ACAAGATCAC CGGAACCTTG GCTTTCACTG TCTTCACTGC TGTACTGAGT 
TCCTTCCAGT TCGGCTATGA CATCGGTGTG ATCAATGCAC CTCAAGAGGT AATAATATCC 
CATTATCGAC ATGTTTTGGG TGTTCCACTG GATGACCGGA AAGCTGCCAT TAACTATGAC 
GTCAATGGCA CAGACACCCC ACTTACAGTC ACACCAGCAT ACACAACACC AGCTCCCTGG 
GATGAAGAGG AGACTGAAGG ATCTGCTCAC ATAGTCACTA TGCTCTGGTC TCTGTCTGTG 
TCCAGCTTTG CAGTGGGCGG AATGGTCGCC TCATTCTTTG GTGGGTGGCT CGGGGACAAA 
CTTGGAAGGA TCAAAGCAAT GTTGGCTGCA AACAGCCTCT CATTGACTGG AGCCCTCTTG 
ATGGGATGTT CCAAATTTGG ACCGGCACAC GCCCTCATCA TTGCTGGACG AAGTGTATCA 
GGACTGTATT GTGGGCTAAT TTCAGGACTG GTTCCAATGT ACATTGGAGA GATCGCTCCA 
ACCACACTCA GGGGTGCCCT GGGTACTCTT CACCAACTGG CCCTTGTCAC AGGCATTCTT 
ATTAGTCAGA TTGCTGGCCT CAGCTTTATT CTGGGCAATC AGGATCATTG GCACATCCTA 
CTTGGCCTAT CTGCTGTGCC AGCTCTTCTG CAGTGTCTGC TACTGCTCTT CTGTCCAGAA 
AGCCCCAGAT ACCTTTATAT AAAGTTGGAA GAGGAAGTCA GGGCAAAGAA AAGCTTGAAG 
AGACTAAGAG GAACTGAGGA TGTCACCAAA GATATTAATG AGATGAAGAA AGAAAAGGAA 
GAGGCATCGA CTGAGCAGAA GGTCTCCGTG ATCCAGCTCT TCACGGATGC CAATTACCGA 
CAGCCCATCC TCGTGGCGCT GATGCTGCAC ATGGCCCAGC AGTTCTCAGG AATCAATGGG 
ATATTTTACT ATTCAACCAG CATTTTTCAG ACAGCTGGCA TCAGCCAGCC TGTGTATGCA 
ACCATTGGTG TTGGGGCCAT CAACATGATC TTCACGGCTG TCTCTGTGCT GCTTGTGGAG 
AAGGCAGGGC GGCGGACCCT GTTCCTAACC GGGATGATTG GCATGTTTTT CTGCACCATC 
TTCATGTCGG TGGGACTTGT GCTGCTGGAT AAATTCGCCT GGATGAGTTA CGTGAGCATG 
ACTGCCATCT TCCTCTTTGT CAGTTTCTTT GAGATTGGGC CAGGTCCAAT CCCTTGGTTC 
ATGGTTGCTG AATTTTTCAG CCAAGGACCC CGTCCTACGG CTCTGGCACT GGCTGCCTTC 
AGCAACTGGG TCTGCAATTT TGTCATCGCC CTCTGCTTCC AGTACATTGC GGACTTCCTT 
GGGCCTTACG TGTTCTTCCT CTTCGCTGGG GTGGTCCTGG TCTTCACCCT GTTTACATTC 
TTTAAAGTTC CAGAAACCAA AGGAAAGTCT TTTGAGGAAA TCGCTGCAGA ATTCCGGAAG 
AAGAGTGGTT CGGCCCCACC ACGCAAAGCT GCTGTACAAA TGGAATTCCT GGCGTCTTCA 
GAGAGTGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112474.2
CDS	115..1686
Translation	MSEDKITGTLAFTVFTAVLSSFQFGYDIGVINAPQEVIISHYRHVLGVPLDDRKAAINYDVNGTDTPLTVTPAYTTPAPWDEEETEGSAHIVTMLWSLSVSSFAVGGMVASFFGGWLGDKLGRIKAMLAANSLSLTGALLMGCSKFGPAHALIIAGRSVSGLYCGLISGLVPMYIGEIAPTTLRGALGTLHQLALVTGILISQIAGLSFILGNQDHWHILLGLSAVPALLQCLLLLFCPESPRYLYIKLEEEVRAKKSLKRLRGTEDVTKDINEMKKEKEEASTEQKVSVIQLFTDANYRQPILVALMLHMAQQFSGINGIFYYSTSIFQTAGISQPVYATIGVGAINMIFTAVSVLLVEKAGRRTLFLTGMIGMFFCTIFMSVGLVLLDKFAWMSYVSMTAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPTALALAAFSNWVCNFVIALCFQYIADFLGPYVFFLFAGVVLVFTLFTFFKVPETKGKSFEEIAAEFRKKSGSAPPRKAAVQMEFLASSESV

Target ORF information:

RefSeq Version	NM_031197.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 2 (facilitated glucose transporter), member 2 (Slc2a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031197.2

ORF Insert Sequence:

ATGTCAGAAG ACAAGATCAC CGGAACCTTG GCTTTCACTG TCTTCACTGC TGTACTGAGT 
TCCTTCCAGT TCGGCTATGA CATCGGTGTG ATCAATGCAC CTCAAGAGGT AATAATATCC 
CATTATCGAC ATGTTTTGGG TGTTCCACTG GATGACCGGA AAGCTGCCAT TAACTATGAC 
GTCAATGGCA CAGACACCCC ACTTACAGTC ACACCAGCAT ACACAACACC AGCTCCCTGG 
GATGAAGAGG AGACTGAAGG ATCTGCTCAC ATAGTCACTA TGCTCTGGTC TCTGTCTGTG 
TCCAGCTTTG CAGTGGGCGG AATGGTCGCC TCATTCTTTG GTGGGTGGCT CGGGGACAAA 
CTTGGAAGGA TCAAAGCAAT GTTGGCTGCA AACAGCCTCT CATTGACTGG AGCCCTCTTG 
ATGGGATGTT CCAAATTTGG ACCGGCACAC GCCCTCATCA TTGCTGGACG AAGTGTATCA 
GGACTGTATT GTGGGCTAAT TTCAGGACTG GTTCCAATGT ACATTGGAGA GATCGCTCCA 
ACCACACTCA GGGGTGCCCT GGGTACTCTT CACCAACTGG CCCTTGTCAC AGGCATTCTT 
ATTAGTCAGA TTGCTGGCCT CAGCTTTATT CTGGGCAATC AGGATCATTG GCACATCCTA 
CTTGGCCTAT CTGCTGTGCC AGCTCTTCTG CAGTGTCTGC TACTGCTCTT CTGTCCAGAA 
AGCCCCAGAT ACCTTTATAT AAAGTTGGAA GAGGAAGTCA GGGCAAAGAA AAGCTTGAAG 
AGACTAAGAG GAACTGAGGA TGTCACCAAA GATATTAATG AGATGAAGAA AGAAAAGGAA 
GAGGCATCGA CTGAGCAGAA GGTCTCCGTG ATCCAGCTCT TCACGGATGC CAATTACCGA 
CAGCCCATCC TCGTGGCGCT GATGCTGCAC ATGGCCCAGC AGTTCTCAGG AATCAATGGG 
ATATTTTACT ATTCAACCAG CATTTTTCAG ACAGCTGGCA TCAGCCAGCC TGTGTATGCA 
ACCATTGGTG TTGGGGCCAT CAACATGATC TTCACGGCTG TCTCTGTGCT GCTTGTGGAG 
AAGGCAGGGC GGCGGACCCT GTTCCTAACC GGGATGATTG GCATGTTTTT CTGCACCATC 
TTCATGTCGG TGGGACTTGT GCTGCTGGAT AAATTCGCCT GGATGAGTTA CGTGAGCATG 
ACTGCCATCT TCCTCTTTGT CAGTTTCTTT GAGATTGGGC CAGGTCCAAT CCCTTGGTTC 
ATGGTTGCTG AATTTTTCAG CCAAGGACCC CGTCCTACGG CTCTGGCACT GGCTGCCTTC 
AGCAACTGGG TCTGCAATTT TGTCATCGCC CTCTGCTTCC AGTACATTGC GGACTTCCTT 
GGGCCTTACG TGTTCTTCCT CTTCGCTGGG GTGGTCCTGG TCTTCACCCT GTTTACATTC 
TTTAAAGTTC CAGAAACCAA AGGAAAGTCT TTTGAGGAAA TCGCTGCAGA ATTCCGGAAG 
AAGAGTGGTT CGGCCCCACC ACGCAAAGCT GCTGTACAAA TGGAATTCCT GGCGTCTTCA 
GAGAGTGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transient Impairment of Islet Architectural Development in Pancreas-Specific Bmpr1a-Deleted Prenatal Mice Involves Reduced Expression of E-Cadherin.
Stem cells and development26(23)1706-1714(2017 Dec)
Jiang FX,Harrison LC

Defining a Novel Role for the Pdx1 Transcription Factor in Islet ?-Cell Maturation and Proliferation During Weaning.
Diabetes66(11)2830-2839(2017 11)
Spaeth JM,Gupte M,Perelis M,Yang YP,Cyphert H,Guo S,Liu JH,Guo M,Bass J,Magnuson MA,Wright C,Stein R

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Slc2a2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報