Sfrp4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sfrp4
Entrez Gene ID	20379
Full Name	secreted frizzled-related protein 4
General protein information	Preferred Names secreted frizzled-related protein 4 Names secreted frizzled-related sequence protein 4 FRP-4 frizzled-related protein 4 sFRP-4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13 A2\|13 6.99 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_016687.3	NP_057896.1	secreted frizzled-related sequence protein 4 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SFRP4	XP_519048.3
Canis lupus familiaris (dog)	SFRP4	XP_540377.2
Gallus gallus (chicken)	SFRP4	XP_418831.4
	SFRP4	NP_001028134.1
Rattus norvegicus (Norway rat)	Sfrp4	NP_445996.1
Xenopus tropicalis (tropical clawed frog)	sfrp4	XP_002939467.2
Mus musculus (house mouse)	Sfrp4	NP_057896.1
Homo sapiens (human)	SFRP4	NP_003005.2
Bos taurus (cattle)	SFRP4	NP_001069232.1

Gene Ontology
Bibliography

Related articles in PubMed

Cerebrovascular defects in Foxc1 mutants correlate with aberrant WNT and VEGF-A pathways downstream of retinoic acid from the meninges.
Mishra S, Choe Y, Pleasure SJ, Siegenthaler JA
Developmental biology420(1)148-165(2016 Dec)

Genetic and physical delineation of the region overlapping the progressive motor neuropathy (pmn) locus on mouse chromosome 13.
Martin N, Jaubert J, Glaser P, Szatanik M, Gu?net JL
Genomics75(1-3)9-16(2001 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the cross-talk between SFRP4, integrin alpha1beta1, and Notch1 suppresses the cardiac differentiation of P19CL6 cells.
Title: Cross-talk of SFRP4, integrin ?1?1, and Notch1 inhibits cardiac differentiation of P19CL6 cells.

Our study showed that Pyle's disease was caused by a deficiency of sFRP4 and that sFRP4-mediated cross-regulation between Wnt and BMP signaling was critical for achieving proper cortical-bone thickness and stability.
Title: Cortical-Bone Fragility--Insights from sFRP4 Deficiency in Pyle's Disease.

In diet-induced obesity, loss of SFRP4 alters body length and bone mineral density as well as energy expenditure and food intake. However, SFRP4 does not control glucose homeostasis and beta-cell mass in mice.
Title: Loss of SFRP4 Alters Body Size, Food Intake, and Energy Expenditure in Diet-Induced Obese Male Mice.

MicroRNA-124 regulates cell specification in the cochlea through modulation of Sfrp4 and Sfrp5.
Title: MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5.

findings suggest that an epigenetic event is critically involved in the pathogenesis of psoriasis, and the downregulation of SFRP4 by CpG island methylation is one possible mechanism contributing to the hyperplasia of epidermis in the disease
Title: Epigenetic downregulation of SFRP4 contributes to epidermal hyperplasia in psoriasis.

The following Sfrp4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sfrp4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu13226	NM_016687.3 Latest version!	Mus musculus secreted frizzled-related protein 4 (Sfrp4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sfrp4 ( NM_016687.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_057896.1 Mus musculus secreted frizzled-related protein 4 (Sfrp4), mRNA.

Price & Availability↑

CloneID	OMu13226
Clone ID Related Accession (Same CDS sequence)	NM_016687.3
Accession Version	NM_016687.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1056bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Mus musculus(house mouse)
Product	secreted frizzled-related sequence protein 4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK080766.1 and BC034853.1. On Jul 10, 2009 this sequence version replaced NM_016687.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC034853.1, AF117709.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCCGCT CCATCCTGGT GGCGTTATGC CTGTGGCTGC GCCTGGCGCT GGGAGTTCGC 
GGAGCGCCCT GCGAAGCTGT GCGCATCCCC ATGTGCAGGC ACATGCCCTG GAACATCACC 
CGGATGCCCA ACCACCTGCA CCACAGCACT CAGGAGAACG CCATCCTGGC CATCGAACAG 
TATGAAGAGC TAGTGGACGT GAACTGCAGC TCTGTGCTGC GCTTCTTCCT TTGTGCCATG 
TACGCACCCA TCTGTACCCT GGAGTTCCTG CACGATCCCA TCAAGCCCTG CAAGTCTGTG 
TGCCAGCGCG CACGTGACGA CTGCGAGCCC CTCATGAAGA TGTATAACCA CAGCTGGCCA 
GAGAGCCTGG CCTGCGATGA GCTGCCGGTC TATGACCGTG GAGTTTGTAT CTCTCCAGAG 
GCAATAGTCA CTGACCTTCC AGAAGATGTG AAGTGGATAG ACATCACACC AGATATGATG 
GTGCAAGAAA GGTCCTTTGA TGCTGACTGT AAACGTCTGA GCCCTGATCG GTGCAAGTGC 
AAAAAGGTGA AGCCGACCCT GGCAACATAC CTGAGCAAAA ACTACAGCTA TGTTATTCAT 
GCCAAAATAA AAGCCGTCCA GAGGAGTGGT TGCAATGAGG TCACAACTGT GGTAGATGTA 
AAAGAGATCT TCAAGTCTTT GTCACCTATC CCTCGAACAC AAGTCCCTCT CATCACCAAT 
TCCTCCTGCC AGTGTCCACA TATCCTGCCC CATCAAGATG TCCTAATCAT GTGTTATGAG 
TGGCGTTCAA GGATGATGCT TCTTGAAAAT TGCTTAGTTG AAAAGTGGAG AGATCAACTC 
AGTAGAAGGT CCATACAGTG GGAAGAGAGG CTTCAGGAAC AGCAGAGAAC AATTCAGGAC 
AAGAAGCAGA TAGCCAGCCG CACCAGTCGC ACCAGTCGCA GTAACCCCCC AAAGTCAAAG 
GGAAGGCCAC CTGCTCCCAA ACCTGCCAGT CCTAAGAAGA ACATCAAAGC TAGAAGTGCC 
CCCAAAAAGT CAAACCTGAA GAAAAGCGCA AGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057896.1
CDS	259..1314
Translation	MLRSILVALCLWLRLALGVRGAPCEAVRIPMCRHMPWNITRMPNHLHHSTQENAILAIEQYEELVDVNCSSVLRFFLCAMYAPICTLEFLHDPIKPCKSVCQRARDDCEPLMKMYNHSWPESLACDELPVYDRGVCISPEAIVTDLPEDVKWIDITPDMMVQERSFDADCKRLSPDRCKCKKVKPTLATYLSKNYSYVIHAKIKAVQRSGCNEVTTVVDVKEIFKSLSPIPRTQVPLITNSSCQCPHILPHQDVLIMCYEWRSRMMLLENCLVEKWRDQLSRRSIQWEERLQEQQRTIQDKKQIASRTSRTSRSNPPKSKGRPPAPKPASPKKNIKARSAPKKSNLKKSAS

Target ORF information:

RefSeq Version	NM_016687.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus secreted frizzled-related protein 4 (Sfrp4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016687.3

ORF Insert Sequence:

ATGCTCCGCT CCATCCTGGT GGCGTTATGC CTGTGGCTGC GCCTGGCGCT GGGAGTTCGC 
GGAGCGCCCT GCGAAGCTGT GCGCATCCCC ATGTGCAGGC ACATGCCCTG GAACATCACC 
CGGATGCCCA ACCACCTGCA CCACAGCACT CAGGAGAACG CCATCCTGGC CATCGAACAG 
TATGAAGAGC TAGTGGACGT GAACTGCAGC TCTGTGCTGC GCTTCTTCCT TTGTGCCATG 
TACGCACCCA TCTGTACCCT GGAGTTCCTG CACGATCCCA TCAAGCCCTG CAAGTCTGTG 
TGCCAGCGCG CACGTGACGA CTGCGAGCCC CTCATGAAGA TGTATAACCA CAGCTGGCCA 
GAGAGCCTGG CCTGCGATGA GCTGCCGGTC TATGACCGTG GAGTTTGTAT CTCTCCAGAG 
GCAATAGTCA CTGACCTTCC AGAAGATGTG AAGTGGATAG ACATCACACC AGATATGATG 
GTGCAAGAAA GGTCCTTTGA TGCTGACTGT AAACGTCTGA GCCCTGATCG GTGCAAGTGC 
AAAAAGGTGA AGCCGACCCT GGCAACATAC CTGAGCAAAA ACTACAGCTA TGTTATTCAT 
GCCAAAATAA AAGCCGTCCA GAGGAGTGGT TGCAATGAGG TCACAACTGT GGTAGATGTA 
AAAGAGATCT TCAAGTCTTT GTCACCTATC CCTCGAACAC AAGTCCCTCT CATCACCAAT 
TCCTCCTGCC AGTGTCCACA TATCCTGCCC CATCAAGATG TCCTAATCAT GTGTTATGAG 
TGGCGTTCAA GGATGATGCT TCTTGAAAAT TGCTTAGTTG AAAAGTGGAG AGATCAACTC 
AGTAGAAGGT CCATACAGTG GGAAGAGAGG CTTCAGGAAC AGCAGAGAAC AATTCAGGAC 
AAGAAGCAGA TAGCCAGCCG CACCAGTCGC ACCAGTCGCA GTAACCCCCC AAAGTCAAAG 
GGAAGGCCAC CTGCTCCCAA ACCTGCCAGT CCTAAGAAGA ACATCAAAGC TAGAAGTGCC 
CCCAAAAAGT CAAACCTGAA GAAAAGCGCA AGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cerebrovascular defects in Foxc1 mutants correlate with aberrant WNT and VEGF-A pathways downstream of retinoic acid from the meninges.
Developmental biology420(1)148-165(2016 Dec)
Mishra S,Choe Y,Pleasure SJ,Siegenthaler JA

Genetic and physical delineation of the region overlapping the progressive motor neuropathy (pmn) locus on mouse chromosome 13.
Genomics75(1-3)9-16(2001 Jul)
Martin N,Jaubert J,Glaser P,Szatanik M,Gu?net JL

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Sfrp4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報