Scn7a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Scn7a
Entrez Gene ID	20272
Full Name	sodium channel, voltage-gated, type VII, alpha
Synonyms	1110034K09Rik,AI642000,NaG,Nav2,Nav2.3,Nax,Scn6a
General protein information	Preferred Names sodium channel, voltage-gated, type VII, alpha Names sodium channel protein type 7 subunit alpha sodium channel, voltage-gated, type VI, alpha polypeptide
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 C1.3\|2 39.21 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_009135.2	NP_033161.2	sodium channel protein type 7 subunit alpha

Pathways from BioSystems

Homologies

Homo sapiens (human)	SCN7A	NP_002967.2
Pan troglodytes (chimpanzee)	SCN7A	XP_515875.4
Canis lupus familiaris (dog)	SCN7A	XP_545504.3
Bos taurus (cattle)	SCN7A	XP_002685417.2
Mus musculus (house mouse)	Scn7a	NP_033161.2
	SCN7A	XP_002808047.1
Rattus norvegicus (Norway rat)	Scn7a	NP_113874.1

Gene Ontology
Bibliography

Related articles in PubMed

Distinct neural mechanisms for the control of thirst and salt appetite in the subfornical organ.
Matsuda T, Hiyama TY, Niimura F, Matsusaka T, Fukamizu A, Kobayashi K, Kobayashi K, Noda M
Nature neuroscience20(2)230-241(2017 Feb)

Nax signaling evoked by an increase in [Na+] in CSF induces water intake via EET-mediated TRPV4 activation.
Sakuta H, Nishihara E, Hiyama TY, Lin CH, Noda M
American journal of physiology. Regulatory, integrative and comparative physiology311(2)R299-306(2016 Aug)

HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3.
Dilg D, Saleh RN, Phelps SE, Rose Y, Dupays L, Murphy C, Mohun T, Anderson RH, Scambler PJ, Chapgier AL
PloS one11(8)e0161096(2016)

The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling.
Budry L, Balsalobre A, Gauthier Y, Khetchoumian K, L'honor? A, Vallette S, Brue T, Figarella-Branger D, Meij B, Drouin J
Genes & development26(20)2299-310(2012 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that the Na(+) signal generated in Nax-positive glial cells leads to the activation of TRPV4-positive neurons in sCVOs to stimulate water intake by using EETs as gliotransmitters.
Title: Nax signaling evoked by an increase in [Na+] in CSF induces water intake via EET-mediated TRPV4 activation.

SAP97 promotes the stability of Nax channels at the plasma membrane.
Title: SAP97 promotes the stability of Nax channels at the plasma membrane.

identified the promoter and transcription start sites of Na(x) sodium channel in dorsal root ganglia neurons; findings provide the basis with which to understand tissue-specific regulation of Nax sodium channel gene (Scn7a) expression
Title: Identification and functional characterization of the promoter of the mouse sodium-activated sodium channel Na(x) gene (Scn7a).

results suggest that glial cells bearing the Na(x) channel are the first to sense a physiological increase in the level of sodium in the body fluid.
Title: Sodium-level-sensitive sodium channel Na(x) is expressed in glial laminate processes in the sensory circumventricular organs.

Results show that the subfornical organ is the center of the control of salt-intake behavior in the brain, where the Na-level-sensitive Na(x) channel is involved in sensing the physiological increase in the Na level of body fluids.
Title: The subfornical organ is the primary locus of sodium-level sensing by Na(x) sodium channels for the control of salt-intake behavior.

The following Scn7a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Scn7a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu03582	NM_009135.2 Latest version!	Mus musculus sodium channel, voltage-gated, type VII, alpha (Scn7a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Scn7a ( NM_009135.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033161.2 Mus musculus sodium channel, voltage-gated, type VII, alpha (Scn7a), mRNA.

Price & Availability↑

CloneID	OMu03582
Clone ID Related Accession (Same CDS sequence)	NM_009135.2
Accession Version	NM_009135.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5046bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-24
Organism	Mus musculus(house mouse)
Product	sodium channel protein type 7 subunit alpha
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL928720.6 and AL928623.5. On Sep 7, 2007 this sequence version replaced NM_009135.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L36179.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGTTGACTT CCCCAGAGCC GAAGGGCCTT GTCCCATTTA CAACAGAGTC ACTTGAACTT 
ATAGAAAATC ACATTGCTAA AAAATGCAAT GAAGACCCCG AAGAAGAAGA AGGTTTAAAA 
CCAAGTCGTA ATCTAGAAGC TGGCAAAAGA CTTCCAATTC CCTATGGAAC CCTCCCTCGA 
GGAACCGTGT CAGAGCCCTT GGAAGATGTG GATCCATACT ACTATGTTAA GAGAAATACT 
TTCATGGTCT TAAACAGAAG CAGAGTCATC TTCAGGTTCA ATGCGGTTTC CATCTTCTGC 
ACATTGTCTC CTCTAAACTC CCTCAGAAGA GCAGCTATCA AGGCTTTGGT GCATCCCCTT 
TTTCGCCTGC TGATTTTAAT CAGCGTTCTC ACTGACAGCA TACTTATGTG CATGAGTAAT 
CTACCAGAAT GGATATTGGC AATAGAGAAT ACTTTGCTTG GGATTTACGC ATTTGAAATA 
CTTGTAAAAG TCATTGCAAG AGGTATCTGG GCAGGTTCAT TTTCCTTCCT TGGGGATCTT 
TGGAACTGGC TTGATTTCAG TGTAACTTTG TTCGAGCTAA TCACAAGGTT TTCACCTCTA 
AGCTCCTTTT TAATGCTTAA AACTATCAGA ACTTTCCGAA TTTTGAAGAT TATCCCTTTG 
AACCACGGCC TGCAGTCTAT TGTGATGACA CTGGCCCAGT GTTTGAAGAA ACTATTTGGT 
GCCATTGCCC TAGCTCTGTT TTTTCTGGCT GTGTTTTCAC TACTTGGAAT GGGCCTCTTC 
ATGGGCAACC TGAAGCACAA ATGTCTGCGG TGGCCAGAAG AAAATGAAAA TGAAACGCTG 
CACAACAGAA CTGGAAGCCT TAACTATAGT CCAGAAAGAA TAAACTTCTA CTACATGGAA 
GGAGCGAAAT ATGCTCTCCT TTGCGGCAAC AGGACAGATG CTGGCCAGTG TCCGGAAGGT 
TATGTGTGTG TAAAAGAAGG CACAAATCCT GACAATGGCT TCACAAGTTT TGACAACTTT 
GGCTGGTCCC TTCTTGCTAT GTTTCGATTG ATGACACAGG ATTACCCTGA ATTACTTTAT 
CACCAGATCC TTTATGCTTC AGGAAAGGTC TACATGATAT TTTTTGTTAT GATCAGTTTC 
TGGTTTGCCT TCTATTTGAC AAGTTTGTTC TTGGGCATAC TCACTATGAC CTATGAAAAG 
GAAAAGCAGA GAGCCTGTGA GGAATCTGGA GGCCTTGATC CCAAATGTCA ACAGACAGTG 
AAAGAACTCG ACGAAGAAAA TGACGCAGCT GAGATGGAAA CTACACAAAT AGAAATGAAG 
AAAAGATCCC CAACTTCTAT AAACACCACA CTGGATATAC TGGAAGACAC TACCCTCGGA 
CACAGAGAAG AACCAGAAAC ATCCAGGAAG AAATGCCCAA TATGTTGGCA TAAGTTTATT 
AAAACCTGCT TCATCTGGAA ATGCTCTCCC TGTTGGGTAA AACTGAACGA GTTTGCTGAT 
AGAGTTATAA CACACCCATT GGCTGATCTT TTTCTTGTCA TCTGCATCGT TTTAAACATA 
TGCTTCCTCG CCCTAGAACA TTTTCCAATG AGCGAGGAGC TCAGGTCTCT CCTTCACGTT 
GGAAATTTGG TTTTTATTGG AATTTACACA ATAGAAATGA TTTTGAAGAT AATCGCTATG 
CATCCATATG GGTATTTTCA AATAAGCTGG AATATTTTTG ACAGTATACT TGTGGTTTTG 
GAGTTAACAG AAATTTTACT AGCAGATGTT GAAGGACTAG CTGTTTTAAT AACAGTCCCA 
TTGATATTTA TAAAACTGGG GAAGTACGGA CCACCATTTA AGAGTTTGAT GCGCATCCTT 
GGTAGCTCAT TGATGGCCCT GAAAGATTTG GTCCTGTTGC TCTGCATATT CGTTTACTTC 
TCTGCTGTGT TCGGCATGAA GCTGTTTGGT CGAAGTTACA AGGATTGTGT CTGCCACATA 
AAGGAAGACT GCCAACCCCA ACGCTGGCAC ATGAGTGACT TCCTTCATGC CTACATGACC 
GTGTTCCGAA TCCTCTGTGG AGAGTGGATA GAGACATTAT GGGAGTGTAT GGAGGTTGCA 
GGCCAGGCCT GGTGTATTCC TTTTTACATG ATGGTCATTT TAATTGGAAA CTTATTGATA 
CTTTACCTCT TTGTGACATT GGTGAGCTCT TTCAGTTACT ATGATGCTAC ATCGGAAGTG 
AACAAAGAAG CCAAAAACCT TCAGCTTGCC ATGGCAAGGA TAAAGTCGGG AATAAACTCC 
ATGCTTCTTA AATTAATGTG CACAGAAAGA AGTGTTCCTA CAGAAGCAAC AGACCAAATA 
TGTGATCCAA GTGTTAAAGA GAATATTTCT GGCCATACTC TTTCTGAACT GAGCAACACC 
CAAACTTTCC TCAGATATAA GGACCAGAGC AGCAGCACTG AGAAAACTCC AGTGACTGAA 
TCTGAGAGTC AATCTCTGAT TGCTAGTCCC AGTGCCTCTG AAACTGTGCC GATTGCTTCA 
GGAGAATCTG ATATAGAAAA TCTGGATAAC AAGGAGACTC GGAGCAAGTC TGGGAATGGA 
GGCAGTAAAG AGAAAATGAA GCAGTCTAGC TCATCTGAGT GCAGCACAGT TGATATCGCT 
ATTTCTGAAG AAGAAGAAAT GGTCTATGAA CATGAAAAGT CAAAGCTTCA TAAAAATGGT 
TATGAACGCA AATCTTCAAC TGGTCAAATC AGTAGAGAAT CTAGGAATGG AAAGATTTGG 
AAAAACATCA GGAAAACTTG CTGCAAGATA GTAGAGAACA GCTGGTTTGA GTGTTTCATT 
GGCCTGGTCA CTCTGCTCTG CACAGGCACT CTGGCTCTTG AAGACATATA TATTGATCAG 
AGAAAAACCA CTAAAATCTT ACTGGAATAT GCGGACATGA TATTTGCATA CATCTTCATT 
CTGGAGATGC TTCTCAAGTG GGTGGCTTAT GGCTTTAAAG CCTTTTTCTC CAACAACTGG 
TACAAACTGG ACTTTATGGT TGTTATCGTG TTTTGTCTTA GCTTAATAGG CAAAACTCGA 
GAAGATCTGA ACCCTCTGAC ATCAATAAAG TTCCTTCGAG CACTAAGAGT TCTGTCGCAG 
TTTGAAAGAA TGAAGGTGGT CCTGAGAGCT TTGATAAAAA CAACCTTACC CACTGTGAGC 
GTGTTTCTAG TCTGCCTAAT GATCTGGCTG CTTTTCAGTG TTATTGGAGT GCAGTTATTT 
GCTGGCAAGT TCTATGAATG CATTGACCCA ACAAAGGGAG AAAGATTCCC TGTATTTGAA 
GTTATGAATA AAAGTCAGTG TGAAAAACTG TTATTCAATG AATCAATGCC GTGGGAGAAT 
GCAAAACTGA ACTTTGATAA TGTTGGAAAT GGTTTTCTTT CTTTACTCCA AGTGGCAACA 
TTTAATGGAT GGATCAGTAT TATGAATTCA GCAATTGATT CTGTTGGTGT AAACATGCAG 
CCCAGCTTTG AGTACAACCT CTACATGTAT AGTTACTTTA TCATCTTTGT TATCTTTGGA 
TTATTTCTTC CTCTCTGTAT GCTGATTGGT GTTATTATTC GCAATTTCAA CAAGCAGAAA 
ATTAAGCAGG GAGGATCAAA CATCTTTATA ACAGTAAAAC AGAAAAAACA GTACCGGGCC 
CTGAAGAAGC TCTTGTATGC AGACGTCCAG AAACCAACAC CCCGCCCCAG AAACAAATTC 
CAAGGCTTCC TTTTTGACCT AGTAACACAC CGTGTCTTTA ATGTTATCAT CATACTTCTT 
ATCTGTTTCC AAGCAACAAC CATTATGATA CAAAAGGATG AGCAGAGTCC ACAAATGGAA 
ACTGCCATCT TCTGGATGAA CTCCATTTTT GTCATGCTGT TCACTCTGGA ATGCATACTG 
AAGCTCACTG CCTTCCGTTG CCACTACTTC ACCAGTGCAT GGAATGTTCA TGACTTTATG 
GTGGTCATTT TCTCCATTAC AGGGCTGCTG CTACCCTTGA CAATAGGACA ATACTTTGTG 
CCTCCTTCCC TGGTGCAGCT GATTCTTCTC TCTCGAGTCA TCCACATCCT GCGTCCTGGG 
AAAGGACCGA AGGTGTTCCA TGACCTGATG CTTCCCTTGA TTCTGGCGCT CCCAGCATTG 
CTGAACATTA GTCTTCTCAT CTTCCTGGTC ATGTTCATCT ACGCCATCTT TGGAATGTAC 
AACTTTGCCT ATGTAAAGAA AGAAGCCGGA ATTAATGATG TGTCCAACTT TGAGACCTTT 
GGAAGCAGTA TGCTCTGTCT CTTCCAAGTT ACAACGTTTT CTGGTTGGGA CGGGATGCTG 
GATGCAATTT TCAACAGTCA GTGGTCTGAC TGCGATCCTG ATAAAATTAA TCCAGGGACT 
CAGGTCAAGG GAGATTGTGG GAGCCCTTCT GTTGGGATTT CTTATTTTGT CAGTTACATC 
CTCATATCAT GGTTGATCAT TGTTAACATG TACATTGTGT TGATCATGGA GTTCTTAAGT 
ATTCCTTCTC AGAAAAAAAG CAGGACCTTG AGTGAAGATG ACTTTAGGAG ATTCTTCCGG 
GTGTGGAACA GGTTTGACCC TGATAGGACC CAGTACATAG ACTCTAGCAA GCTTTCTGAT 
TTTGCAGCTG CTCTGGATCC TCCTCTTTTC ATGGCAAAAC CAAACAAGGG CCAGCTTGTG 
GCCATGGATC TCCCCATGGC TGCGGGAGAC AGAATCCACT GCCTCGACAT TTTACTTGCC 
TTTACGAAAA GAGTGATGGG AAAGGATGAG AGGGTGGAGA AAATCCTTTC AGAGATAGAA 
TCCGGGTTCA TGTTAGCGAA CCCTTTCAAA ATCACTTATG AGCCGATTAC AACTACTTTG 
AAACGCAAAC AAGAGGCAGT TTCAGCAACC ATCATCCAGC GTGCATATAA AAGCTACCGC 
TTAAGGCAAA ATGACAAGAA TGTATCAGAT ACTCCTGCTA TAGATGACCG CAGAGATGAT 
CTTACTTCTA AAGGTGCTCA CTCTGGCAAA ATCGAGGAGA AGGCATCTAT TCAGACCCAG 
ATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033161.2
CDS	216..5261
Translation	MLTSPEPKGLVPFTTESLELIENHIAKKCNEDPEEEEGLKPSRNLEAGKRLPIPYGTLPRGTVSEPLEDVDPYYYVKRNTFMVLNRSRVIFRFNAVSIFCTLSPLNSLRRAAIKALVHPLFRLLILISVLTDSILMCMSNLPEWILAIENTLLGIYAFEILVKVIARGIWAGSFSFLGDLWNWLDFSVTLFELITRFSPLSSFLMLKTIRTFRILKIIPLNHGLQSIVMTLAQCLKKLFGAIALALFFLAVFSLLGMGLFMGNLKHKCLRWPEENENETLHNRTGSLNYSPERINFYYMEGAKYALLCGNRTDAGQCPEGYVCVKEGTNPDNGFTSFDNFGWSLLAMFRLMTQDYPELLYHQILYASGKVYMIFFVMISFWFAFYLTSLFLGILTMTYEKEKQRACEESGGLDPKCQQTVKELDEENDAAEMETTQIEMKKRSPTSINTTLDILEDTTLGHREEPETSRKKCPICWHKFIKTCFIWKCSPCWVKLNEFADRVITHPLADLFLVICIVLNICFLALEHFPMSEELRSLLHVGNLVFIGIYTIEMILKIIAMHPYGYFQISWNIFDSILVVLELTEILLADVEGLAVLITVPLIFIKLGKYGPPFKSLMRILGSSLMALKDLVLLLCIFVYFSAVFGMKLFGRSYKDCVCHIKEDCQPQRWHMSDFLHAYMTVFRILCGEWIETLWECMEVAGQAWCIPFYMMVILIGNLLILYLFVTLVSSFSYYDATSEVNKEAKNLQLAMARIKSGINSMLLKLMCTERSVPTEATDQICDPSVKENISGHTLSELSNTQTFLRYKDQSSSTEKTPVTESESQSLIASPSASETVPIASGESDIENLDNKETRSKSGNGGSKEKMKQSSSSECSTVDIAISEEEEMVYEHEKSKLHKNGYERKSSTGQISRESRNGKIWKNIRKTCCKIVENSWFECFIGLVTLLCTGTLALEDIYIDQRKTTKILLEYADMIFAYIFILEMLLKWVAYGFKAFFSNNWYKLDFMVVIVFCLSLIGKTREDLNPLTSIKFLRALRVLSQFERMKVVLRALIKTTLPTVSVFLVCLMIWLLFSVIGVQLFAGKFYECIDPTKGERFPVFEVMNKSQCEKLLFNESMPWENAKLNFDNVGNGFLSLLQVATFNGWISIMNSAIDSVGVNMQPSFEYNLYMYSYFIIFVIFGLFLPLCMLIGVIIRNFNKQKIKQGGSNIFITVKQKKQYRALKKLLYADVQKPTPRPRNKFQGFLFDLVTHRVFNVIIILLICFQATTIMIQKDEQSPQMETAIFWMNSIFVMLFTLECILKLTAFRCHYFTSAWNVHDFMVVIFSITGLLLPLTIGQYFVPPSLVQLILLSRVIHILRPGKGPKVFHDLMLPLILALPALLNISLLIFLVMFIYAIFGMYNFAYVKKEAGINDVSNFETFGSSMLCLFQVTTFSGWDGMLDAIFNSQWSDCDPDKINPGTQVKGDCGSPSVGISYFVSYILISWLIIVNMYIVLIMEFLSIPSQKKSRTLSEDDFRRFFRVWNRFDPDRTQYIDSSKLSDFAAALDPPLFMAKPNKGQLVAMDLPMAAGDRIHCLDILLAFTKRVMGKDERVEKILSEIESGFMLANPFKITYEPITTTLKRKQEAVSATIIQRAYKSYRLRQNDKNVSDTPAIDDRRDDLTSKGAHSGKIEEKASIQTQI

Target ORF information:

RefSeq Version	NM_009135.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus sodium channel, voltage-gated, type VII, alpha (Scn7a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009135.2

ORF Insert Sequence:

ATGTTGACTT CCCCAGAGCC GAAGGGCCTT GTCCCATTTA CAACAGAGTC ACTTGAACTT 
ATAGAAAATC ACATTGCTAA AAAATGCAAT GAAGACCCCG AAGAAGAAGA AGGTTTAAAA 
CCAAGTCGTA ATCTAGAAGC TGGCAAAAGA CTTCCAATTC CCTATGGAAC CCTCCCTCGA 
GGAACCGTGT CAGAGCCCTT GGAAGATGTG GATCCATACT ACTATGTTAA GAGAAATACT 
TTCATGGTCT TAAACAGAAG CAGAGTCATC TTCAGGTTCA ATGCGGTTTC CATCTTCTGC 
ACATTGTCTC CTCTAAACTC CCTCAGAAGA GCAGCTATCA AGGCTTTGGT GCATCCCCTT 
TTTCGCCTGC TGATTTTAAT CAGCGTTCTC ACTGACAGCA TACTTATGTG CATGAGTAAT 
CTACCAGAAT GGATATTGGC AATAGAGAAT ACTTTGCTTG GGATTTACGC ATTTGAAATA 
CTTGTAAAAG TCATTGCAAG AGGTATCTGG GCAGGTTCAT TTTCCTTCCT TGGGGATCTT 
TGGAACTGGC TTGATTTCAG TGTAACTTTG TTCGAGCTAA TCACAAGGTT TTCACCTCTA 
AGCTCCTTTT TAATGCTTAA AACTATCAGA ACTTTCCGAA TTTTGAAGAT TATCCCTTTG 
AACCACGGCC TGCAGTCTAT TGTGATGACA CTGGCCCAGT GTTTGAAGAA ACTATTTGGT 
GCCATTGCCC TAGCTCTGTT TTTTCTGGCT GTGTTTTCAC TACTTGGAAT GGGCCTCTTC 
ATGGGCAACC TGAAGCACAA ATGTCTGCGG TGGCCAGAAG AAAATGAAAA TGAAACGCTG 
CACAACAGAA CTGGAAGCCT TAACTATAGT CCAGAAAGAA TAAACTTCTA CTACATGGAA 
GGAGCGAAAT ATGCTCTCCT TTGCGGCAAC AGGACAGATG CTGGCCAGTG TCCGGAAGGT 
TATGTGTGTG TAAAAGAAGG CACAAATCCT GACAATGGCT TCACAAGTTT TGACAACTTT 
GGCTGGTCCC TTCTTGCTAT GTTTCGATTG ATGACACAGG ATTACCCTGA ATTACTTTAT 
CACCAGATCC TTTATGCTTC AGGAAAGGTC TACATGATAT TTTTTGTTAT GATCAGTTTC 
TGGTTTGCCT TCTATTTGAC AAGTTTGTTC TTGGGCATAC TCACTATGAC CTATGAAAAG 
GAAAAGCAGA GAGCCTGTGA GGAATCTGGA GGCCTTGATC CCAAATGTCA ACAGACAGTG 
AAAGAACTCG ACGAAGAAAA TGACGCAGCT GAGATGGAAA CTACACAAAT AGAAATGAAG 
AAAAGATCCC CAACTTCTAT AAACACCACA CTGGATATAC TGGAAGACAC TACCCTCGGA 
CACAGAGAAG AACCAGAAAC ATCCAGGAAG AAATGCCCAA TATGTTGGCA TAAGTTTATT 
AAAACCTGCT TCATCTGGAA ATGCTCTCCC TGTTGGGTAA AACTGAACGA GTTTGCTGAT 
AGAGTTATAA CACACCCATT GGCTGATCTT TTTCTTGTCA TCTGCATCGT TTTAAACATA 
TGCTTCCTCG CCCTAGAACA TTTTCCAATG AGCGAGGAGC TCAGGTCTCT CCTTCACGTT 
GGAAATTTGG TTTTTATTGG AATTTACACA ATAGAAATGA TTTTGAAGAT AATCGCTATG 
CATCCATATG GGTATTTTCA AATAAGCTGG AATATTTTTG ACAGTATACT TGTGGTTTTG 
GAGTTAACAG AAATTTTACT AGCAGATGTT GAAGGACTAG CTGTTTTAAT AACAGTCCCA 
TTGATATTTA TAAAACTGGG GAAGTACGGA CCACCATTTA AGAGTTTGAT GCGCATCCTT 
GGTAGCTCAT TGATGGCCCT GAAAGATTTG GTCCTGTTGC TCTGCATATT CGTTTACTTC 
TCTGCTGTGT TCGGCATGAA GCTGTTTGGT CGAAGTTACA AGGATTGTGT CTGCCACATA 
AAGGAAGACT GCCAACCCCA ACGCTGGCAC ATGAGTGACT TCCTTCATGC CTACATGACC 
GTGTTCCGAA TCCTCTGTGG AGAGTGGATA GAGACATTAT GGGAGTGTAT GGAGGTTGCA 
GGCCAGGCCT GGTGTATTCC TTTTTACATG ATGGTCATTT TAATTGGAAA CTTATTGATA 
CTTTACCTCT TTGTGACATT GGTGAGCTCT TTCAGTTACT ATGATGCTAC ATCGGAAGTG 
AACAAAGAAG CCAAAAACCT TCAGCTTGCC ATGGCAAGGA TAAAGTCGGG AATAAACTCC 
ATGCTTCTTA AATTAATGTG CACAGAAAGA AGTGTTCCTA CAGAAGCAAC AGACCAAATA 
TGTGATCCAA GTGTTAAAGA GAATATTTCT GGCCATACTC TTTCTGAACT GAGCAACACC 
CAAACTTTCC TCAGATATAA GGACCAGAGC AGCAGCACTG AGAAAACTCC AGTGACTGAA 
TCTGAGAGTC AATCTCTGAT TGCTAGTCCC AGTGCCTCTG AAACTGTGCC GATTGCTTCA 
GGAGAATCTG ATATAGAAAA TCTGGATAAC AAGGAGACTC GGAGCAAGTC TGGGAATGGA 
GGCAGTAAAG AGAAAATGAA GCAGTCTAGC TCATCTGAGT GCAGCACAGT TGATATCGCT 
ATTTCTGAAG AAGAAGAAAT GGTCTATGAA CATGAAAAGT CAAAGCTTCA TAAAAATGGT 
TATGAACGCA AATCTTCAAC TGGTCAAATC AGTAGAGAAT CTAGGAATGG AAAGATTTGG 
AAAAACATCA GGAAAACTTG CTGCAAGATA GTAGAGAACA GCTGGTTTGA GTGTTTCATT 
GGCCTGGTCA CTCTGCTCTG CACAGGCACT CTGGCTCTTG AAGACATATA TATTGATCAG 
AGAAAAACCA CTAAAATCTT ACTGGAATAT GCGGACATGA TATTTGCATA CATCTTCATT 
CTGGAGATGC TTCTCAAGTG GGTGGCTTAT GGCTTTAAAG CCTTTTTCTC CAACAACTGG 
TACAAACTGG ACTTTATGGT TGTTATCGTG TTTTGTCTTA GCTTAATAGG CAAAACTCGA 
GAAGATCTGA ACCCTCTGAC ATCAATAAAG TTCCTTCGAG CACTAAGAGT TCTGTCGCAG 
TTTGAAAGAA TGAAGGTGGT CCTGAGAGCT TTGATAAAAA CAACCTTACC CACTGTGAGC 
GTGTTTCTAG TCTGCCTAAT GATCTGGCTG CTTTTCAGTG TTATTGGAGT GCAGTTATTT 
GCTGGCAAGT TCTATGAATG CATTGACCCA ACAAAGGGAG AAAGATTCCC TGTATTTGAA 
GTTATGAATA AAAGTCAGTG TGAAAAACTG TTATTCAATG AATCAATGCC GTGGGAGAAT 
GCAAAACTGA ACTTTGATAA TGTTGGAAAT GGTTTTCTTT CTTTACTCCA AGTGGCAACA 
TTTAATGGAT GGATCAGTAT TATGAATTCA GCAATTGATT CTGTTGGTGT AAACATGCAG 
CCCAGCTTTG AGTACAACCT CTACATGTAT AGTTACTTTA TCATCTTTGT TATCTTTGGA 
TTATTTCTTC CTCTCTGTAT GCTGATTGGT GTTATTATTC GCAATTTCAA CAAGCAGAAA 
ATTAAGCAGG GAGGATCAAA CATCTTTATA ACAGTAAAAC AGAAAAAACA GTACCGGGCC 
CTGAAGAAGC TCTTGTATGC AGACGTCCAG AAACCAACAC CCCGCCCCAG AAACAAATTC 
CAAGGCTTCC TTTTTGACCT AGTAACACAC CGTGTCTTTA ATGTTATCAT CATACTTCTT 
ATCTGTTTCC AAGCAACAAC CATTATGATA CAAAAGGATG AGCAGAGTCC ACAAATGGAA 
ACTGCCATCT TCTGGATGAA CTCCATTTTT GTCATGCTGT TCACTCTGGA ATGCATACTG 
AAGCTCACTG CCTTCCGTTG CCACTACTTC ACCAGTGCAT GGAATGTTCA TGACTTTATG 
GTGGTCATTT TCTCCATTAC AGGGCTGCTG CTACCCTTGA CAATAGGACA ATACTTTGTG 
CCTCCTTCCC TGGTGCAGCT GATTCTTCTC TCTCGAGTCA TCCACATCCT GCGTCCTGGG 
AAAGGACCGA AGGTGTTCCA TGACCTGATG CTTCCCTTGA TTCTGGCGCT CCCAGCATTG 
CTGAACATTA GTCTTCTCAT CTTCCTGGTC ATGTTCATCT ACGCCATCTT TGGAATGTAC 
AACTTTGCCT ATGTAAAGAA AGAAGCCGGA ATTAATGATG TGTCCAACTT TGAGACCTTT 
GGAAGCAGTA TGCTCTGTCT CTTCCAAGTT ACAACGTTTT CTGGTTGGGA CGGGATGCTG 
GATGCAATTT TCAACAGTCA GTGGTCTGAC TGCGATCCTG ATAAAATTAA TCCAGGGACT 
CAGGTCAAGG GAGATTGTGG GAGCCCTTCT GTTGGGATTT CTTATTTTGT CAGTTACATC 
CTCATATCAT GGTTGATCAT TGTTAACATG TACATTGTGT TGATCATGGA GTTCTTAAGT 
ATTCCTTCTC AGAAAAAAAG CAGGACCTTG AGTGAAGATG ACTTTAGGAG ATTCTTCCGG 
GTGTGGAACA GGTTTGACCC TGATAGGACC CAGTACATAG ACTCTAGCAA GCTTTCTGAT 
TTTGCAGCTG CTCTGGATCC TCCTCTTTTC ATGGCAAAAC CAAACAAGGG CCAGCTTGTG 
GCCATGGATC TCCCCATGGC TGCGGGAGAC AGAATCCACT GCCTCGACAT TTTACTTGCC 
TTTACGAAAA GAGTGATGGG AAAGGATGAG AGGGTGGAGA AAATCCTTTC AGAGATAGAA 
TCCGGGTTCA TGTTAGCGAA CCCTTTCAAA ATCACTTATG AGCCGATTAC AACTACTTTG 
AAACGCAAAC AAGAGGCAGT TTCAGCAACC ATCATCCAGC GTGCATATAA AAGCTACCGC 
TTAAGGCAAA ATGACAAGAA TGTATCAGAT ACTCCTGCTA TAGATGACCG CAGAGATGAT 
CTTACTTCTA AAGGTGCTCA CTCTGGCAAA ATCGAGGAGA AGGCATCTAT TCAGACCCAG 
ATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Distinct neural mechanisms for the control of thirst and salt appetite in the subfornical organ.
Nature neuroscience20(2)230-241(2017 Feb)
Matsuda T,Hiyama TY,Niimura F,Matsusaka T,Fukamizu A,Kobayashi K,Kobayashi K,Noda M

Nax signaling evoked by an increase in [Na+] in CSF induces water intake via EET-mediated TRPV4 activation.
American journal of physiology. Regulatory, integrative and comparative physiology311(2)R299-306(2016 Aug)
Sakuta H,Nishihara E,Hiyama TY,Lin CH,Noda M

HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3.
PloS one11(8)e0161096(2016)
Dilg D,Saleh RN,Phelps SE,Rose Y,Dupays L,Murphy C,Mohun T,Anderson RH,Scambler PJ,Chapgier AL

The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling.
Genes & development26(20)2299-310(2012 Oct)
Budry L,Balsalobre A,Gauthier Y,Khetchoumian K,L'honor? A,Vallette S,Brue T,Figarella-Branger D,Meij B,Drouin J

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Scn7a cDNA ORF clone, Mus musculus(house mouse)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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