Clec11a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Clec11a
Entrez Gene ID	20256
Full Name	C-type lectin domain family 11, member a
Synonyms	AW457320,Clecsf3,Scgf
General protein information	Preferred Names C-type lectin domain family 11, member a Names C-type lectin domain family 11 member A lymphocyte secreted C-type lectin osteolectin stem cell growth factor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 B3

mRNA and Protein(s)

mRNA	Protein	Name
NM_009131.3	NP_033157.1	C-type lectin domain family 11 member A precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CLEC11A	XP_001173878.1
	CLEC11A	XP_001116136.1
Canis lupus familiaris (dog)	CLEC11A	XP_854623.2
Homo sapiens (human)	CLEC11A	NP_002966.1
Bos taurus (cattle)	CLEC11A	NP_001091523.1
Mus musculus (house mouse)	Clec11a	NP_033157.1
Rattus norvegicus (Norway rat)	Clec11a	NP_001012477.1

Gene Ontology
Bibliography

Related articles in PubMed

Clec11a/osteolectin is an osteogenic growth factor that promotes the maintenance of the adult skeleton.
Yue R, Shen B, Morrison SJ
eLife5(2016 12)

Developmental gene expression profiling of mammalian, fetal orofacial tissue.
Mukhopadhyay P, Greene RM, Zacharias W, Weinrich MC, Singh S, Young WW Jr, Pisano MM
Birth defects research. Part A, Clinical and molecular teratology70(12)912-26(2004 Dec)

Genomic analysis of mouse retinal development.
Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL
PLoS biology2(9)E247(2004 Sep)

Stem cell factor-induced leukotriene B4 production cooperates with eotaxin to mediate the recruitment of eosinophils during allergic pleurisy in mice.
Klein A, Talvani A, Silva PM, Martins MA, Wells TN, Proudfoot A, Luckacs NW, Teixeira MM
Journal of immunology (Baltimore, Md. : 1950)167(1)524-31(2001 Jul)

Stem cell growth factor: in situ hybridization analysis on the gene expression, molecular characterization and in vitro proliferative activity of a recombinant preparation on primitive hematopoietic progenitor cells.
Hiraoka A, Yano Ki K, Kagami N, Takeshige K, Mio H, Anazawa H, Sugimoto S
The hematology journal : the official journal of the European Haematology Association2(5)307-15(2001)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This protein mediates eosinophil recruitment in a mouse model of allergic pleurisy via production of the chemoattractant lipid leukotriene B4.
Title: Stem cell factor-induced leukotriene B4 production cooperates with eotaxin to mediate the recruitment of eosinophils during allergic pleurisy in mice.

In situ hybridization of whole mouse fetuses and their tibias demonstrated expression of SCGF mRNA around skeletal tissues, particularly in bone marrow cells, proliferating chondrocytes, the perichondrium and periosteum.
Title: Stem cell growth factor: in situ hybridization analysis on the gene expression, molecular characterization and in vitro proliferative activity of a recombinant preparation on primitive hematopoietic progenitor cells.

The following Clec11a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Clec11a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu03572	NM_009131.3 Latest version!	Mus musculus C-type lectin domain family 11, member a (Clec11a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Clec11a ( NM_009131.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033157.1 Mus musculus C-type lectin domain family 11, member a (Clec11a), mRNA.

Price & Availability↑

CloneID	OMu03572
Clone ID Related Accession (Same CDS sequence)	NM_009131.3
Accession Version	NM_009131.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	C-type lectin domain family 11 member A precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY137682.1, BY115987.1, BB850120.1, BE860221.1, AC152939.2, AK042963.1 and CD741904.1. On Jul 10, 2009 this sequence version replaced NM_009131.2. ##Evidence-Data-START## Transcript exon combination :: BC002001.1, AB009245.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN01164137 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGGCAG CCTGGCTCTT GGGGGCCCTA GTGGTCCCTC AGCTTTTGAG TTTTGGTCAT 
GGAGCCCGAG GTCCTGGGAG GGAGTGGGAG GGAGGCTGGG GAGGTGCCCT GGAGGAGGAG 
AGAGAGCGGG AGTCACAGAT GTTGAAGAAT CTCCAGGAGG CCCTAGGGCT GCCCACTGGG 
GTGGGAAATG AGGATAATCT TGCTGAAAAC CCTGAAGACA AAGAGGTCTG GGAGACCACA 
GAGACTCAAG GGGAAGAAGA GGAAGAGGAA ATCACCACAG CACCTTCTTC TAGTCCCAAC 
CCTTTCCCCA GCCCTTCTCC CACACCAGAG GACACTGTCA CTTACATCTT GGGCCGCTTG 
GCCAGCCTCG ATGCAGGCCT ACACCAATTG CACGTCCGTC TGCACGTTTT GGACACCCGT 
GTGGTTGAGC TGACCCAGGG GCTGCGGCAG CTGCGGGATG CTGCGAGTGA CACCCGCGAC 
TCAGTGCAAG CCCTGAAGGA GGTCCAGGAC CGTGCTGAGC AGGAGCACGG CCGCTTGGAG 
GGCTGCCTGA AGGGCCTGCG CCTTGGCCAC AAGTGCTTCC TGCTCTCGCG AGACTTCGAG 
ACCCAGGCGG CGGCGCAGGC GCGGTGCAAG GCGCGAGGTG GGAGCTTAGC ACAGCCTGCG 
GACCGCCAGC AAATGGATGC GCTAAGCCGG TACTTACGCG CCGCTCTCGC CCCCTACAAC 
TGGCCGGTGT GGCTGGGAGT GCACGATCGG CGCTCCGAGG GGCTCTACCT TTTCGAGAAC 
GGCCAGCGCG TGTCTTTCTT CGCCTGGCAC CGCGCATTCA GCCTGGAGTC CGGCGCCCAG 
CCTAGTGCGG CAACACATCC ACTCAGCCCG GATCAGCCCA ATGGCGGCGT CCTGGAGAAC 
TGCGTGGCCC AGGCCTCAGA CGACGGTTCT TGGTGGGACC ATGACTGTGA GCGGCGCCTC 
TACTTCGTCT GCGAGTTCCC CTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033157.1
CDS	195..1181
Translation	MQAAWLLGALVVPQLLSFGHGARGPGREWEGGWGGALEEERERESQMLKNLQEALGLPTGVGNEDNLAENPEDKEVWETTETQGEEEEEEITTAPSSSPNPFPSPSPTPEDTVTYILGRLASLDAGLHQLHVRLHVLDTRVVELTQGLRQLRDAASDTRDSVQALKEVQDRAEQEHGRLEGCLKGLRLGHKCFLLSRDFETQAAAQARCKARGGSLAQPADRQQMDALSRYLRAALAPYNWPVWLGVHDRRSEGLYLFENGQRVSFFAWHRAFSLESGAQPSAATHPLSPDQPNGGVLENCVAQASDDGSWWDHDCERRLYFVCEFPF

Target ORF information:

RefSeq Version	NM_009131.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus C-type lectin domain family 11, member a (Clec11a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009131.3

ORF Insert Sequence:

ATGCAGGCAG CCTGGCTCTT GGGGGCCCTA GTGGTCCCTC AGCTTTTGAG TTTTGGTCAT 
GGAGCCCGAG GTCCTGGGAG GGAGTGGGAG GGAGGCTGGG GAGGTGCCCT GGAGGAGGAG 
AGAGAGCGGG AGTCACAGAT GTTGAAGAAT CTCCAGGAGG CCCTAGGGCT GCCCACTGGG 
GTGGGAAATG AGGATAATCT TGCTGAAAAC CCTGAAGACA AAGAGGTCTG GGAGACCACA 
GAGACTCAAG GGGAAGAAGA GGAAGAGGAA ATCACCACAG CACCTTCTTC TAGTCCCAAC 
CCTTTCCCCA GCCCTTCTCC CACACCAGAG GACACTGTCA CTTACATCTT GGGCCGCTTG 
GCCAGCCTCG ATGCAGGCCT ACACCAATTG CACGTCCGTC TGCACGTTTT GGACACCCGT 
GTGGTTGAGC TGACCCAGGG GCTGCGGCAG CTGCGGGATG CTGCGAGTGA CACCCGCGAC 
TCAGTGCAAG CCCTGAAGGA GGTCCAGGAC CGTGCTGAGC AGGAGCACGG CCGCTTGGAG 
GGCTGCCTGA AGGGCCTGCG CCTTGGCCAC AAGTGCTTCC TGCTCTCGCG AGACTTCGAG 
ACCCAGGCGG CGGCGCAGGC GCGGTGCAAG GCGCGAGGTG GGAGCTTAGC ACAGCCTGCG 
GACCGCCAGC AAATGGATGC GCTAAGCCGG TACTTACGCG CCGCTCTCGC CCCCTACAAC 
TGGCCGGTGT GGCTGGGAGT GCACGATCGG CGCTCCGAGG GGCTCTACCT TTTCGAGAAC 
GGCCAGCGCG TGTCTTTCTT CGCCTGGCAC CGCGCATTCA GCCTGGAGTC CGGCGCCCAG 
CCTAGTGCGG CAACACATCC ACTCAGCCCG GATCAGCCCA ATGGCGGCGT CCTGGAGAAC 
TGCGTGGCCC AGGCCTCAGA CGACGGTTCT TGGTGGGACC ATGACTGTGA GCGGCGCCTC 
TACTTCGTCT GCGAGTTCCC CTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Clec11a/osteolectin is an osteogenic growth factor that promotes the maintenance of the adult skeleton.
eLife5(2016 12)
Yue R,Shen B,Morrison SJ

Developmental gene expression profiling of mammalian, fetal orofacial tissue.
Birth defects research. Part A, Clinical and molecular teratology70(12)912-26(2004 Dec)
Mukhopadhyay P,Greene RM,Zacharias W,Weinrich MC,Singh S,Young WW Jr,Pisano MM

Genomic analysis of mouse retinal development.
PLoS biology2(9)E247(2004 Sep)
Blackshaw S,Harpavat S,Trimarchi J,Cai L,Huang H,Kuo WP,Weber G,Lee K,Fraioli RE,Cho SH,Yung R,Asch E,Ohno-Machado L,Wong WH,Cepko CL

Stem cell factor-induced leukotriene B4 production cooperates with eotaxin to mediate the recruitment of eosinophils during allergic pleurisy in mice.
Journal of immunology (Baltimore, Md. : 1950)167(1)524-31(2001 Jul)
Klein A,Talvani A,Silva PM,Martins MA,Wells TN,Proudfoot A,Luckacs NW,Teixeira MM

Stem cell growth factor: in situ hybridization analysis on the gene expression, molecular characterization and in vitro proliferative activity of a recombinant preparation on primitive hematopoietic progenitor cells.
The hematology journal : the official journal of the European Haematology Association2(5)307-15(2001)
Hiraoka A,Yano Ki K,Kagami N,Takeshige K,Mio H,Anazawa H,Sugimoto S

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Clec11a cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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