Rbl2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rbl2
Entrez Gene ID	19651
Full Name	RB transcriptional corepressor like 2
Synonyms	PRB2,RBR-2,Rb2,p130
General protein information	Preferred Names RB transcriptional corepressor like 2 Names retinoblastoma-like protein 2 130 kDa retinoblastoma-associated protein retinoblastoma-like 2 retinoblastoma-related protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8 C4\|8 44.25 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001282001.1	NP_001268930.1	retinoblastoma-like protein 2 isoform 3
NM_001282000.1	NP_001268929.1	retinoblastoma-like protein 2 isoform 2
NM_011250.4	NP_035380.3	retinoblastoma-like protein 2 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	RBL2	XP_523371.2
Canis lupus familiaris (dog)	RBL2	XP_535303.2
Danio rerio (zebrafish)	rbl2	XP_002667000.3
	RBL2	XP_002802522.1
Drosophila melanogaster (fruit fly)	Rbf	NP_525036.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006477	XP_316517.4
Bos taurus (cattle)	RBL2	NP_001091542.1
Rattus norvegicus (Norway rat)	Rbl2	NP_112356.1
Homo sapiens (human)	RBL2	NP_005602.3
Mus musculus (house mouse)	Rbl2	NP_035380.3
Xenopus tropicalis (tropical clawed frog)	rbl2	XP_002937369.2

Gene Ontology
Bibliography

Related articles in PubMed

The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner.
Hwang SH, White KA, Somatilaka BN, Shelton JM, Richardson JA, Mukhopadhyay S
Development (Cambridge, England)145(1)(2018 Jan)

Dnmt1-dependent Chk1 pathway suppression is protective against neuron division.
Oshikawa M, Okada K, Tabata H, Nagata KI, Ajioka I
Development (Cambridge, England)144(18)3303-3314(2017 09)

Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression.
Kim E, Cheng Y, Bolton-Gillespie E, Cai X, Ma C, Tarangelo A, Le L, Jambhekar M, Raman P, Hayer KE, Wertheim G, Speck NA, Tong W, Viatour P
The Journal of experimental medicine214(7)1901-1912(2017 Jul)

CHK1 Inhibition in Small-Cell Lung Cancer Produces Single-Agent Activity in Biomarker-Defined Disease Subsets and Combination Activity with Cisplatin or Olaparib.
Sen T, Tong P, Stewart CA, Cristea S, Valliani A, Shames DS, Redwood AB, Fan YH, Li L, Glisson BS, Minna JD, Sage J, Gibbons DL, Piwnica-Worms H, Heymach JV, Wang J, Byers LA
Cancer research77(14)3870-3884(2017 Jul)

Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer.
Lim JS, Ibaseta A, Fischer MM, Cancilla B, O'Young G, Cristea S, Luca VC, Yang D, Jahchan NS, Hamard C, Antoine M, Wislez M, Kong C, Cain J, Liu YW, Kapoun AM, Garcia KC, Hoey T, Murriel CL, Sage J
Nature545(7654)360-364(2017 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Findings indicate that inactivation of the Rb family proteins (Rb, p107, and p130) in hematopoietic stem cells (HSCs) progressively impairs their homeostasis, which is rescued upon repression of suppressor of cytokine signaling 3 protein (Socs3) expression in triple knockout (TKO) HSCs.
Title: Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression.

Loss of Rb 130 gene is associated with retinoblastoma.
Title: Genomic landscape of retinoblastoma in Rb

Deletion of Rb or p130 leads to impaired repression of Sox2, a defect amplified by inactivation of p53. Identify binding of pRb and p130 to an enhancer with crucial regulatory activity on Sox2 expression.
Title: Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins.

In skeletal dysplasias cell cycle progression is compromised in the G1 phase due to reduced phosphorylation of the pocket protein p130 leading to inhibition of transcription factors of the E2F family.
Title: Altered signaling in the G1 phase deregulates chondrocyte growth in a mouse model with proteoglycan undersulfation.

Following stress exposure, E2F4-p130 complexes are lost rapidly along with the presence of E2F4 at E2F-containing B-Myb promoter sites.
Title: Regulation of ischemic neuronal death by E2F4-p130 protein complexes.

The following Rbl2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rbl2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu19867	NM_001282001.1 Latest version!	Mus musculus RB transcriptional corepressor like 2 (Rbl2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OMu23171	NM_011250.4 Latest version!	Mus musculus RB transcriptional corepressor like 2 (Rbl2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OMu23256	NM_001282000.1 Latest version!	Mus musculus RB transcriptional corepressor like 2 (Rbl2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rbl2 ( NM_001282001.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001268930.1 Mus musculus RB transcriptional corepressor like 2 (Rbl2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu19867
Clone ID Related Accession (Same CDS sequence)	NM_001282001.1
Accession Version	NM_001282001.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3378bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-20
Organism	Mus musculus(house mouse)
Product	retinoblastoma-like protein 2 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY270001.1, AK160027.1, CF736271.1 and AI323872.1. Transcript Variant: This variant (3) uses an alternate in-frame splice site in the central coding region, compared to variant 1. The encoded isoform (3) is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U36799.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164133 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCTG GAGGCAACCA GTCGCCACCG CCTCCTCCAG CTGCTGCAGC CAGCTCGGAG 
GAAGAGGAGG AGGATGGCGA CGCCGCGGAT CGCGCGCAGC CCGCGGGGTC CCCGAGCCAT 
CAGATCCAGC AGCGGTTCGA GGAGCTGTGC AGCCGCCTCA ACATGGACGA GGCGGCGCGC 
GCCGAGGCCT GGAGCAGCTA CCGCAGCATG AGCGAGAGCT ACACGCTGGA GGGAAATGAC 
CTTCATTGGT TAGCATGTGC CTTATATGTG GCTTGCAGAA AATCTGTTCC AACTGTGAGC 
AAAGGGACCG CTGAAGGAAA CTATGTATCT TTAACCAGAA TCCTTCGCTG TTCGGAGCAG 
AGCCTAATTG AATTTTTTAA CAAGATGAAG AAGTGGGAAG ACATGGCAAA TCTGCCCCCA 
CATTTCCGAG AACGTACTGA AAGATTAGAA AGAAACTTCA CTGTTTCTGC TGTGATTTTT 
AAGAAATATG AACCCATTTT TCAAGACATT TTTAAATATC CCCAAGAAGA ACAGCCTCGC 
CAGCAAAGAG GAAGAAAACA GAGGCGACAG CCCTGTACCA CATCAGAAAT TTTCCATTTT 
TGCTGGGTGC TTTTTATATA TGCGAAAGGG AACTTCCCCA TGATTAGCGA TGATCTGGTC 
AATTCCTACC ATCTTCTGCT GTGCGCATTA GATTTAGTCT ATGGAAATGC CCTTCAGTGT 
TCTAACCGTA AAGAACTTGT GAACCCTAAT TTTAAAGGCC TGTCCGAGGA CTGTCACCCC 
AAGGACTCTA AAGCGTCCTC CGACCCGCCG TGTGTCATTG AGAAGCTGTG CTCCTTACAC 
GACGGTCTAG TGTTGGAGGC CAAGGGGATA AAGGAACACT TCTGGAAACC CTATATTAGG 
AAACTGTTTG AGAAAAAGCT TCTCAAGGGG AAGGAAGAAA ATCTTACTGG CTTCCTGGAG 
CCCGGAAACT TTGGAGAGAG TTTTAAGGCC GTTAATAAGG CATATGAAGA ATACGTGTTA 
GCCGCTGGGA ATCTGGATGA GCGCGTATTC CTTGGTGAGG ATGCTGAGGA GGAAGTTGGG 
ACTCTGTCTC GGTGTCTAAG TGCTGCCTCA GGTACAGAGA GTGCTGAACG GACGCAGATG 
AGAGACATCT TGCAGCAGCA TCTTGACAAG TCTAAAGCAC TTAGAGTCTG CACACCACTG 
ACTGGCGTGA GGTATGTTCA GGAGAACAGC CCGTGTGTGA CTCCCGTCTC CACAGCTGCA 
CACAGCCTGA GCCGTCTTCA CACCATGCTG TCCGGCCTCA GGAATGCACC CAGTGAGAAG 
CTGGAGCGGA TACTCAGGTC ATGTTCCCGA GATCCAACTC AGGCTATCGC TGACAGATTG 
AAAGAAATGT ACGAAATATA TTCTCAGCAT TTCCAGCCAG ATGAGAATTT TAGTAATTGT 
GCTAAAGAAA TGCTCTACTA TAAAGTATTA GAGTCTGTTA TTGAGCAAGA ACAAAAAAGA 
TTGGGAGACA TGGATTTATC TGGTGTTCTG GAGCATGACG CATTCCACAG GTCACTCTTG 
GCCTGCTGCC TTGAGGTGGT CGCTTTTTCC CATAAGCCTC CTGGGAATTT TCCATTTATT 
GCTGAAATAT TTGATGTACC ACATTATCAT TTTTATAAGG TAATTGAAGT ATTTATTAGA 
GCAGAAGACG GTCTTTGCAG AGAAGTGGTC AAACACCTCA ATCAGATTGA AGAACAAATT 
TTAGACCATT TGGCATGGAA AACCAAGTCC CCACTGTGGG ACAGAATTAG AGATAATGAA 
AACAGAGTCC CTACTTGTGA AGAGGTCATG CCACCTCAAA ACCTAGAGAG AACAGATGAA 
ATTTACATCG CTGGCTCTCC CTTAACCCCG AGAAGGGTGG GTGAAGTTCG TGCTGATGCT 
GGAGGACTTG GAAGAAGTAT AACGTCTCCA ACCACATTGT ATGACAGGTA CAGCTCCCCA 
ACAGTCAGCA CTACTAGAAG GCGGCTATTC GAGAATGATA GTCCCTCTGA AGGAAGCACA 
TCTGGGCGCA TCCCCCCACA ACCCCTAGTC AACGCTGTCC CCGTGCAGAA TGTACCTGGG 
GAGACTGTTT CTGTCACACC AGTTCCTGGA CAGACCTTGG TCACCATGGC AACAGCCACT 
GTCACGGCCA ACAATGGACA AACAGTGACC ATTCCAGTCC AAGGTATTGC CAACGAAAAT 
GGAGGGATAA CCTTCTTCCC AGTCCAAGTC AACGTTGGGG GCCAGGCCCA GGCTGTCGCT 
GGCTCTATCC AGCCCCTCAG TGCTCAAGCA CTGGCTGGAA GTCTGAGTTC CCAACAGGTG 
ACAGGAACCA CTTTGCAAGT CCCTGGTCCG GTGGCCATTC AACAGATTTC CCCTGGTGGA 
CAACAGCAGA ACCCAGGCCA GCCACTAACC AGCAGCAGTA TCCGGCCGCG GAAGACTAGC 
TCCTTAGCGC TCTTCTTTAG AAAGGTTTAC TACTTAGCCG GTGTCCGCCT TCGAGATCTT 
TGTATAAAAC TAGATATTTC AGATGAACTG AGGAAAAAAA TTTGGACCTG CTTTGAATTC 
TCTATAATCC AGTGCACCGA ACTTATGATG GACAGACATC TGGACCAGCT GTTGATGTGT 
GCCATTTATG TGATGGCAAA GGTCACAAAA GAAGACAGGT CCTTCCAGAA CATCATGCGT 
TGTTACAGAA CTCAGCCACA GGCCCGGAGC CAGGTGTACA GAAGTGTCTT GATAAAAGGG 
AAAAGAAGAA ACTCTGGCAG CAGTGAGAGC AGAAGCCATC AGAATTCTCC AACCGAACTA 
AATACAGACA GAGCCAGTAG AGATTCCAGC CCAGTGATGA GGTCAAACAG CACCCTACCA 
GTTCCACAGC CCAGCAGTGC CCCTCCTACA CCAACTCGAC TCACGGGTGC CAGCAGTGAC 
GTTGAAGAGG AGGAACGAGG AGACCTCATT CAGTTCTACA ACAACATCTA TAGGAAGCAA 
ATCCAAGCGT TTGCCATGAA GTACTCGCAG GCAAACGCGC AGACGGACAC TCCTCCCCTC 
TCTCCCTATC CATTTGTAAG AACAGGCTCC CCTCGCCGAG TACAGTTATC TCAAAGTCAT 
CCTATCTACA TTTCCCCACA TAACAACGAA GCAATGCCTT CTCCTCGAGA GAAGATTTTT 
TACTACTTCA GCAACAGCCC ATCAAAGAGA CTGAGGGAAA TCAACAGTAT GATACGGACA 
GGAGAGACTC CAACTAAAAA GAGAGGGATT CTCTTGGACG ACGGAAGTGA ATCACCTGCA 
AAAAGAATCT GCCCAGAGAA TCACTCTGCT CTGTTACGTC GTCTCCAGGA TGTGGCGAAT 
GACCGAGGTT CACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001268930.1
CDS	120..3497
Translation	MASGGNQSPPPPPAAAASSEEEEEDGDAADRAQPAGSPSHQIQQRFEELCSRLNMDEAARAEAWSSYRSMSESYTLEGNDLHWLACALYVACRKSVPTVSKGTAEGNYVSLTRILRCSEQSLIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQQRGRKQRRQPCTTSEIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCSNRKELVNPNFKGLSEDCHPKDSKASSDPPCVIEKLCSLHDGLVLEAKGIKEHFWKPYIRKLFEKKLLKGKEENLTGFLEPGNFGESFKAVNKAYEEYVLAAGNLDERVFLGEDAEEEVGTLSRCLSAASGTESAERTQMRDILQQHLDKSKALRVCTPLTGVRYVQENSPCVTPVSTAAHSLSRLHTMLSGLRNAPSEKLERILRSCSRDPTQAIADRLKEMYEIYSQHFQPDENFSNCAKEMLYYKVLESVIEQEQKRLGDMDLSGVLEHDAFHRSLLACCLEVVAFSHKPPGNFPFIAEIFDVPHYHFYKVIEVFIRAEDGLCREVVKHLNQIEEQILDHLAWKTKSPLWDRIRDNENRVPTCEEVMPPQNLERTDEIYIAGSPLTPRRVGEVRADAGGLGRSITSPTTLYDRYSSPTVSTTRRRLFENDSPSEGSTSGRIPPQPLVNAVPVQNVPGETVSVTPVPGQTLVTMATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGGQAQAVAGSIQPLSAQALAGSLSSQQVTGTTLQVPGPVAIQQISPGGQQQNPGQPLTSSSIRPRKTSSLALFFRKVYYLAGVRLRDLCIKLDISDELRKKIWTCFEFSIIQCTELMMDRHLDQLLMCAIYVMAKVTKEDRSFQNIMRCYRTQPQARSQVYRSVLIKGKRRNSGSSESRSHQNSPTELNTDRASRDSSPVMRSNSTLPVPQPSSAPPTPTRLTGASSDVEEEERGDLIQFYNNIYRKQIQAFAMKYSQANAQTDTPPLSPYPFVRTGSPRRVQLSQSHPIYISPHNNEAMPSPREKIFYYFSNSPSKRLREINSMIRTGETPTKKRGILLDDGSESPAKRICPENHSALLRRLQDVANDRGSQ

Target ORF information:

RefSeq Version	NM_001282001.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus RB transcriptional corepressor like 2 (Rbl2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282001.1

ORF Insert Sequence:

ATGGCATCTG GAGGCAACCA GTCGCCACCG CCTCCTCCAG CTGCTGCAGC CAGCTCGGAG 
GAAGAGGAGG AGGATGGCGA CGCCGCGGAT CGCGCGCAGC CCGCGGGGTC CCCGAGCCAT 
CAGATCCAGC AGCGGTTCGA GGAGCTGTGC AGCCGCCTCA ACATGGACGA GGCGGCGCGC 
GCCGAGGCCT GGAGCAGCTA CCGCAGCATG AGCGAGAGCT ACACGCTGGA GGGAAATGAC 
CTTCATTGGT TAGCATGTGC CTTATATGTG GCTTGCAGAA AATCTGTTCC AACTGTGAGC 
AAAGGGACCG CTGAAGGAAA CTATGTATCT TTAACCAGAA TCCTTCGCTG TTCGGAGCAG 
AGCCTAATTG AATTTTTTAA CAAGATGAAG AAGTGGGAAG ACATGGCAAA TCTGCCCCCA 
CATTTCCGAG AACGTACTGA AAGATTAGAA AGAAACTTCA CTGTTTCTGC TGTGATTTTT 
AAGAAATATG AACCCATTTT TCAAGACATT TTTAAATATC CCCAAGAAGA ACAGCCTCGC 
CAGCAAAGAG GAAGAAAACA GAGGCGACAG CCCTGTACCA CATCAGAAAT TTTCCATTTT 
TGCTGGGTGC TTTTTATATA TGCGAAAGGG AACTTCCCCA TGATTAGCGA TGATCTGGTC 
AATTCCTACC ATCTTCTGCT GTGCGCATTA GATTTAGTCT ATGGAAATGC CCTTCAGTGT 
TCTAACCGTA AAGAACTTGT GAACCCTAAT TTTAAAGGCC TGTCCGAGGA CTGTCACCCC 
AAGGACTCTA AAGCGTCCTC CGACCCGCCG TGTGTCATTG AGAAGCTGTG CTCCTTACAC 
GACGGTCTAG TGTTGGAGGC CAAGGGGATA AAGGAACACT TCTGGAAACC CTATATTAGG 
AAACTGTTTG AGAAAAAGCT TCTCAAGGGG AAGGAAGAAA ATCTTACTGG CTTCCTGGAG 
CCCGGAAACT TTGGAGAGAG TTTTAAGGCC GTTAATAAGG CATATGAAGA ATACGTGTTA 
GCCGCTGGGA ATCTGGATGA GCGCGTATTC CTTGGTGAGG ATGCTGAGGA GGAAGTTGGG 
ACTCTGTCTC GGTGTCTAAG TGCTGCCTCA GGTACAGAGA GTGCTGAACG GACGCAGATG 
AGAGACATCT TGCAGCAGCA TCTTGACAAG TCTAAAGCAC TTAGAGTCTG CACACCACTG 
ACTGGCGTGA GGTATGTTCA GGAGAACAGC CCGTGTGTGA CTCCCGTCTC CACAGCTGCA 
CACAGCCTGA GCCGTCTTCA CACCATGCTG TCCGGCCTCA GGAATGCACC CAGTGAGAAG 
CTGGAGCGGA TACTCAGGTC ATGTTCCCGA GATCCAACTC AGGCTATCGC TGACAGATTG 
AAAGAAATGT ACGAAATATA TTCTCAGCAT TTCCAGCCAG ATGAGAATTT TAGTAATTGT 
GCTAAAGAAA TGCTCTACTA TAAAGTATTA GAGTCTGTTA TTGAGCAAGA ACAAAAAAGA 
TTGGGAGACA TGGATTTATC TGGTGTTCTG GAGCATGACG CATTCCACAG GTCACTCTTG 
GCCTGCTGCC TTGAGGTGGT CGCTTTTTCC CATAAGCCTC CTGGGAATTT TCCATTTATT 
GCTGAAATAT TTGATGTACC ACATTATCAT TTTTATAAGG TAATTGAAGT ATTTATTAGA 
GCAGAAGACG GTCTTTGCAG AGAAGTGGTC AAACACCTCA ATCAGATTGA AGAACAAATT 
TTAGACCATT TGGCATGGAA AACCAAGTCC CCACTGTGGG ACAGAATTAG AGATAATGAA 
AACAGAGTCC CTACTTGTGA AGAGGTCATG CCACCTCAAA ACCTAGAGAG AACAGATGAA 
ATTTACATCG CTGGCTCTCC CTTAACCCCG AGAAGGGTGG GTGAAGTTCG TGCTGATGCT 
GGAGGACTTG GAAGAAGTAT AACGTCTCCA ACCACATTGT ATGACAGGTA CAGCTCCCCA 
ACAGTCAGCA CTACTAGAAG GCGGCTATTC GAGAATGATA GTCCCTCTGA AGGAAGCACA 
TCTGGGCGCA TCCCCCCACA ACCCCTAGTC AACGCTGTCC CCGTGCAGAA TGTACCTGGG 
GAGACTGTTT CTGTCACACC AGTTCCTGGA CAGACCTTGG TCACCATGGC AACAGCCACT 
GTCACGGCCA ACAATGGACA AACAGTGACC ATTCCAGTCC AAGGTATTGC CAACGAAAAT 
GGAGGGATAA CCTTCTTCCC AGTCCAAGTC AACGTTGGGG GCCAGGCCCA GGCTGTCGCT 
GGCTCTATCC AGCCCCTCAG TGCTCAAGCA CTGGCTGGAA GTCTGAGTTC CCAACAGGTG 
ACAGGAACCA CTTTGCAAGT CCCTGGTCCG GTGGCCATTC AACAGATTTC CCCTGGTGGA 
CAACAGCAGA ACCCAGGCCA GCCACTAACC AGCAGCAGTA TCCGGCCGCG GAAGACTAGC 
TCCTTAGCGC TCTTCTTTAG AAAGGTTTAC TACTTAGCCG GTGTCCGCCT TCGAGATCTT 
TGTATAAAAC TAGATATTTC AGATGAACTG AGGAAAAAAA TTTGGACCTG CTTTGAATTC 
TCTATAATCC AGTGCACCGA ACTTATGATG GACAGACATC TGGACCAGCT GTTGATGTGT 
GCCATTTATG TGATGGCAAA GGTCACAAAA GAAGACAGGT CCTTCCAGAA CATCATGCGT 
TGTTACAGAA CTCAGCCACA GGCCCGGAGC CAGGTGTACA GAAGTGTCTT GATAAAAGGG 
AAAAGAAGAA ACTCTGGCAG CAGTGAGAGC AGAAGCCATC AGAATTCTCC AACCGAACTA 
AATACAGACA GAGCCAGTAG AGATTCCAGC CCAGTGATGA GGTCAAACAG CACCCTACCA 
GTTCCACAGC CCAGCAGTGC CCCTCCTACA CCAACTCGAC TCACGGGTGC CAGCAGTGAC 
GTTGAAGAGG AGGAACGAGG AGACCTCATT CAGTTCTACA ACAACATCTA TAGGAAGCAA 
ATCCAAGCGT TTGCCATGAA GTACTCGCAG GCAAACGCGC AGACGGACAC TCCTCCCCTC 
TCTCCCTATC CATTTGTAAG AACAGGCTCC CCTCGCCGAG TACAGTTATC TCAAAGTCAT 
CCTATCTACA TTTCCCCACA TAACAACGAA GCAATGCCTT CTCCTCGAGA GAAGATTTTT 
TACTACTTCA GCAACAGCCC ATCAAAGAGA CTGAGGGAAA TCAACAGTAT GATACGGACA 
GGAGAGACTC CAACTAAAAA GAGAGGGATT CTCTTGGACG ACGGAAGTGA ATCACCTGCA 
AAAAGAATCT GCCCAGAGAA TCACTCTGCT CTGTTACGTC GTCTCCAGGA TGTGGCGAAT 
GACCGAGGTT CACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rbl2 ( NM_011250.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035380.3 Mus musculus RB transcriptional corepressor like 2 (Rbl2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu23171
Clone ID Related Accession (Same CDS sequence)	NM_011250.4
Accession Version	NM_011250.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3408bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-20
Organism	Mus musculus(house mouse)
Product	retinoblastoma-like protein 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY270001.1, AK160027.1, CF736271.1 and AI323872.1. On Aug 14, 2013 this sequence version replaced NM_011250.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC020528.1, SRR1660813.168476.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCTG GAGGCAACCA GTCGCCACCG CCTCCTCCAG CTGCTGCAGC CAGCTCGGAG 
GAAGAGGAGG AGGATGGCGA CGCCGCGGAT CGCGCGCAGC CCGCGGGGTC CCCGAGCCAT 
CAGATCCAGC AGCGGTTCGA GGAGCTGTGC AGCCGCCTCA ACATGGACGA GGCGGCGCGC 
GCCGAGGCCT GGAGCAGCTA CCGCAGCATG AGCGAGAGCT ACACGCTGGA GGGAAATGAC 
CTTCATTGGT TAGCATGTGC CTTATATGTG GCTTGCAGAA AATCTGTTCC AACTGTGAGC 
AAAGGGACCG CTGAAGGAAA CTATGTATCT TTAACCAGAA TCCTTCGCTG TTCGGAGCAG 
AGCCTAATTG AATTTTTTAA CAAGATGAAG AAGTGGGAAG ACATGGCAAA TCTGCCCCCA 
CATTTCCGAG AACGTACTGA AAGATTAGAA AGAAACTTCA CTGTTTCTGC TGTGATTTTT 
AAGAAATATG AACCCATTTT TCAAGACATT TTTAAATATC CCCAAGAAGA ACAGCCTCGC 
CAGCAAAGAG GAAGAAAACA GAGGCGACAG CCCTGTACCA CATCAGAAAT TTTCCATTTT 
TGCTGGGTGC TTTTTATATA TGCGAAAGGG AACTTCCCCA TGATTAGCGA TGATCTGGTC 
AATTCCTACC ATCTTCTGCT GTGCGCATTA GATTTAGTCT ATGGAAATGC CCTTCAGTGT 
TCTAACCGTA AAGAACTTGT GAACCCTAAT TTTAAAGGCC TGTCCGAGGA CTGTCACCCC 
AAGGACTCTA AAGCGTCCTC CGACCCGCCG TGTGTCATTG AGAAGCTGTG CTCCTTACAC 
GACGGTCTAG TGTTGGAGGC CAAGGGGATA AAGGAACACT TCTGGAAACC CTATATTAGG 
AAACTGTTTG AGAAAAAGCT TCTCAAGGGG AAGGAAGAAA ATCTTACTGG CTTCCTGGAG 
CCCGGAAACT TTGGAGAGAG TTTTAAGGCC GTTAATAAGG CATATGAAGA ATACGTGTTA 
GCCGCTGGGA ATCTGGATGA GCGCGTATTC CTTGGTGAGG ATGCTGAGGA GGAAGTTGGG 
ACTCTGTCTC GGTGTCTAAG TGCTGCCTCA GGTACAGAGA GTGCTGAACG GACGCAGATG 
AGAGACATCT TGCAGCAGCA TCTTGACAAG TCTAAAGCAC TTAGAGTCTG CACACCACTG 
ACTGGCGTGA GGTATGTTCA GGAGAACAGC CCGTGTGTGA CTCCCGTCTC CACAGCTGCA 
CACAGCCTGA GCCGTCTTCA CACCATGCTG TCCGGCCTCA GGAATGCACC CAGTGAGAAG 
CTGGAGCGGA TACTCAGGTC ATGTTCCCGA GATCCAACTC AGGCTATCGC TGACAGATTG 
AAAGAAATGT ACGAAATATA TTCTCAGCAT TTCCAGCCAG ATGAGAATTT TAGTAATTGT 
GCTAAAGAAA TTGCCAACAA ACATTTTCGT TTTGCAGAAA TGCTCTACTA TAAAGTATTA 
GAGTCTGTTA TTGAGCAAGA ACAAAAAAGA TTGGGAGACA TGGATTTATC TGGTGTTCTG 
GAGCATGACG CATTCCACAG GTCACTCTTG GCCTGCTGCC TTGAGGTGGT CGCTTTTTCC 
CATAAGCCTC CTGGGAATTT TCCATTTATT GCTGAAATAT TTGATGTACC ACATTATCAT 
TTTTATAAGG TAATTGAAGT ATTTATTAGA GCAGAAGACG GTCTTTGCAG AGAAGTGGTC 
AAACACCTCA ATCAGATTGA AGAACAAATT TTAGACCATT TGGCATGGAA AACCAAGTCC 
CCACTGTGGG ACAGAATTAG AGATAATGAA AACAGAGTCC CTACTTGTGA AGAGGTCATG 
CCACCTCAAA ACCTAGAGAG AACAGATGAA ATTTACATCG CTGGCTCTCC CTTAACCCCG 
AGAAGGGTGG GTGAAGTTCG TGCTGATGCT GGAGGACTTG GAAGAAGTAT AACGTCTCCA 
ACCACATTGT ATGACAGGTA CAGCTCCCCA ACAGTCAGCA CTACTAGAAG GCGGCTATTC 
GAGAATGATA GTCCCTCTGA AGGAAGCACA TCTGGGCGCA TCCCCCCACA ACCCCTAGTC 
AACGCTGTCC CCGTGCAGAA TGTACCTGGG GAGACTGTTT CTGTCACACC AGTTCCTGGA 
CAGACCTTGG TCACCATGGC AACAGCCACT GTCACGGCCA ACAATGGACA AACAGTGACC 
ATTCCAGTCC AAGGTATTGC CAACGAAAAT GGAGGGATAA CCTTCTTCCC AGTCCAAGTC 
AACGTTGGGG GCCAGGCCCA GGCTGTCGCT GGCTCTATCC AGCCCCTCAG TGCTCAAGCA 
CTGGCTGGAA GTCTGAGTTC CCAACAGGTG ACAGGAACCA CTTTGCAAGT CCCTGGTCCG 
GTGGCCATTC AACAGATTTC CCCTGGTGGA CAACAGCAGA ACCCAGGCCA GCCACTAACC 
AGCAGCAGTA TCCGGCCGCG GAAGACTAGC TCCTTAGCGC TCTTCTTTAG AAAGGTTTAC 
TACTTAGCCG GTGTCCGCCT TCGAGATCTT TGTATAAAAC TAGATATTTC AGATGAACTG 
AGGAAAAAAA TTTGGACCTG CTTTGAATTC TCTATAATCC AGTGCACCGA ACTTATGATG 
GACAGACATC TGGACCAGCT GTTGATGTGT GCCATTTATG TGATGGCAAA GGTCACAAAA 
GAAGACAGGT CCTTCCAGAA CATCATGCGT TGTTACAGAA CTCAGCCACA GGCCCGGAGC 
CAGGTGTACA GAAGTGTCTT GATAAAAGGG AAAAGAAGAA ACTCTGGCAG CAGTGAGAGC 
AGAAGCCATC AGAATTCTCC AACCGAACTA AATACAGACA GAGCCAGTAG AGATTCCAGC 
CCAGTGATGA GGTCAAACAG CACCCTACCA GTTCCACAGC CCAGCAGTGC CCCTCCTACA 
CCAACTCGAC TCACGGGTGC CAGCAGTGAC GTTGAAGAGG AGGAACGAGG AGACCTCATT 
CAGTTCTACA ACAACATCTA TAGGAAGCAA ATCCAAGCGT TTGCCATGAA GTACTCGCAG 
GCAAACGCGC AGACGGACAC TCCTCCCCTC TCTCCCTATC CATTTGTAAG AACAGGCTCC 
CCTCGCCGAG TACAGTTATC TCAAAGTCAT CCTATCTACA TTTCCCCACA TAACAACGAA 
GCAATGCCTT CTCCTCGAGA GAAGATTTTT TACTACTTCA GCAACAGCCC ATCAAAGAGA 
CTGAGGGAAA TCAACAGTAT GATACGGACA GGAGAGACTC CAACTAAAAA GAGAGGGATT 
CTCTTGGACG ACGGAAGTGA ATCACCTGCA AAAAGAATCT GCCCAGAGAA TCACTCTGCT 
CTGTTACGTC GTCTCCAGGA TGTGGCGAAT GACCGAGGTT CACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035380.3
CDS	120..3527
Translation	MASGGNQSPPPPPAAAASSEEEEEDGDAADRAQPAGSPSHQIQQRFEELCSRLNMDEAARAEAWSSYRSMSESYTLEGNDLHWLACALYVACRKSVPTVSKGTAEGNYVSLTRILRCSEQSLIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQQRGRKQRRQPCTTSEIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCSNRKELVNPNFKGLSEDCHPKDSKASSDPPCVIEKLCSLHDGLVLEAKGIKEHFWKPYIRKLFEKKLLKGKEENLTGFLEPGNFGESFKAVNKAYEEYVLAAGNLDERVFLGEDAEEEVGTLSRCLSAASGTESAERTQMRDILQQHLDKSKALRVCTPLTGVRYVQENSPCVTPVSTAAHSLSRLHTMLSGLRNAPSEKLERILRSCSRDPTQAIADRLKEMYEIYSQHFQPDENFSNCAKEIANKHFRFAEMLYYKVLESVIEQEQKRLGDMDLSGVLEHDAFHRSLLACCLEVVAFSHKPPGNFPFIAEIFDVPHYHFYKVIEVFIRAEDGLCREVVKHLNQIEEQILDHLAWKTKSPLWDRIRDNENRVPTCEEVMPPQNLERTDEIYIAGSPLTPRRVGEVRADAGGLGRSITSPTTLYDRYSSPTVSTTRRRLFENDSPSEGSTSGRIPPQPLVNAVPVQNVPGETVSVTPVPGQTLVTMATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGGQAQAVAGSIQPLSAQALAGSLSSQQVTGTTLQVPGPVAIQQISPGGQQQNPGQPLTSSSIRPRKTSSLALFFRKVYYLAGVRLRDLCIKLDISDELRKKIWTCFEFSIIQCTELMMDRHLDQLLMCAIYVMAKVTKEDRSFQNIMRCYRTQPQARSQVYRSVLIKGKRRNSGSSESRSHQNSPTELNTDRASRDSSPVMRSNSTLPVPQPSSAPPTPTRLTGASSDVEEEERGDLIQFYNNIYRKQIQAFAMKYSQANAQTDTPPLSPYPFVRTGSPRRVQLSQSHPIYISPHNNEAMPSPREKIFYYFSNSPSKRLREINSMIRTGETPTKKRGILLDDGSESPAKRICPENHSALLRRLQDVANDRGSQ

Target ORF information:

RefSeq Version	NM_011250.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus RB transcriptional corepressor like 2 (Rbl2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011250.4

ORF Insert Sequence:

ATGGCATCTG GAGGCAACCA GTCGCCACCG CCTCCTCCAG CTGCTGCAGC CAGCTCGGAG 
GAAGAGGAGG AGGATGGCGA CGCCGCGGAT CGCGCGCAGC CCGCGGGGTC CCCGAGCCAT 
CAGATCCAGC AGCGGTTCGA GGAGCTGTGC AGCCGCCTCA ACATGGACGA GGCGGCGCGC 
GCCGAGGCCT GGAGCAGCTA CCGCAGCATG AGCGAGAGCT ACACGCTGGA GGGAAATGAC 
CTTCATTGGT TAGCATGTGC CTTATATGTG GCTTGCAGAA AATCTGTTCC AACTGTGAGC 
AAAGGGACCG CTGAAGGAAA CTATGTATCT TTAACCAGAA TCCTTCGCTG TTCGGAGCAG 
AGCCTAATTG AATTTTTTAA CAAGATGAAG AAGTGGGAAG ACATGGCAAA TCTGCCCCCA 
CATTTCCGAG AACGTACTGA AAGATTAGAA AGAAACTTCA CTGTTTCTGC TGTGATTTTT 
AAGAAATATG AACCCATTTT TCAAGACATT TTTAAATATC CCCAAGAAGA ACAGCCTCGC 
CAGCAAAGAG GAAGAAAACA GAGGCGACAG CCCTGTACCA CATCAGAAAT TTTCCATTTT 
TGCTGGGTGC TTTTTATATA TGCGAAAGGG AACTTCCCCA TGATTAGCGA TGATCTGGTC 
AATTCCTACC ATCTTCTGCT GTGCGCATTA GATTTAGTCT ATGGAAATGC CCTTCAGTGT 
TCTAACCGTA AAGAACTTGT GAACCCTAAT TTTAAAGGCC TGTCCGAGGA CTGTCACCCC 
AAGGACTCTA AAGCGTCCTC CGACCCGCCG TGTGTCATTG AGAAGCTGTG CTCCTTACAC 
GACGGTCTAG TGTTGGAGGC CAAGGGGATA AAGGAACACT TCTGGAAACC CTATATTAGG 
AAACTGTTTG AGAAAAAGCT TCTCAAGGGG AAGGAAGAAA ATCTTACTGG CTTCCTGGAG 
CCCGGAAACT TTGGAGAGAG TTTTAAGGCC GTTAATAAGG CATATGAAGA ATACGTGTTA 
GCCGCTGGGA ATCTGGATGA GCGCGTATTC CTTGGTGAGG ATGCTGAGGA GGAAGTTGGG 
ACTCTGTCTC GGTGTCTAAG TGCTGCCTCA GGTACAGAGA GTGCTGAACG GACGCAGATG 
AGAGACATCT TGCAGCAGCA TCTTGACAAG TCTAAAGCAC TTAGAGTCTG CACACCACTG 
ACTGGCGTGA GGTATGTTCA GGAGAACAGC CCGTGTGTGA CTCCCGTCTC CACAGCTGCA 
CACAGCCTGA GCCGTCTTCA CACCATGCTG TCCGGCCTCA GGAATGCACC CAGTGAGAAG 
CTGGAGCGGA TACTCAGGTC ATGTTCCCGA GATCCAACTC AGGCTATCGC TGACAGATTG 
AAAGAAATGT ACGAAATATA TTCTCAGCAT TTCCAGCCAG ATGAGAATTT TAGTAATTGT 
GCTAAAGAAA TTGCCAACAA ACATTTTCGT TTTGCAGAAA TGCTCTACTA TAAAGTATTA 
GAGTCTGTTA TTGAGCAAGA ACAAAAAAGA TTGGGAGACA TGGATTTATC TGGTGTTCTG 
GAGCATGACG CATTCCACAG GTCACTCTTG GCCTGCTGCC TTGAGGTGGT CGCTTTTTCC 
CATAAGCCTC CTGGGAATTT TCCATTTATT GCTGAAATAT TTGATGTACC ACATTATCAT 
TTTTATAAGG TAATTGAAGT ATTTATTAGA GCAGAAGACG GTCTTTGCAG AGAAGTGGTC 
AAACACCTCA ATCAGATTGA AGAACAAATT TTAGACCATT TGGCATGGAA AACCAAGTCC 
CCACTGTGGG ACAGAATTAG AGATAATGAA AACAGAGTCC CTACTTGTGA AGAGGTCATG 
CCACCTCAAA ACCTAGAGAG AACAGATGAA ATTTACATCG CTGGCTCTCC CTTAACCCCG 
AGAAGGGTGG GTGAAGTTCG TGCTGATGCT GGAGGACTTG GAAGAAGTAT AACGTCTCCA 
ACCACATTGT ATGACAGGTA CAGCTCCCCA ACAGTCAGCA CTACTAGAAG GCGGCTATTC 
GAGAATGATA GTCCCTCTGA AGGAAGCACA TCTGGGCGCA TCCCCCCACA ACCCCTAGTC 
AACGCTGTCC CCGTGCAGAA TGTACCTGGG GAGACTGTTT CTGTCACACC AGTTCCTGGA 
CAGACCTTGG TCACCATGGC AACAGCCACT GTCACGGCCA ACAATGGACA AACAGTGACC 
ATTCCAGTCC AAGGTATTGC CAACGAAAAT GGAGGGATAA CCTTCTTCCC AGTCCAAGTC 
AACGTTGGGG GCCAGGCCCA GGCTGTCGCT GGCTCTATCC AGCCCCTCAG TGCTCAAGCA 
CTGGCTGGAA GTCTGAGTTC CCAACAGGTG ACAGGAACCA CTTTGCAAGT CCCTGGTCCG 
GTGGCCATTC AACAGATTTC CCCTGGTGGA CAACAGCAGA ACCCAGGCCA GCCACTAACC 
AGCAGCAGTA TCCGGCCGCG GAAGACTAGC TCCTTAGCGC TCTTCTTTAG AAAGGTTTAC 
TACTTAGCCG GTGTCCGCCT TCGAGATCTT TGTATAAAAC TAGATATTTC AGATGAACTG 
AGGAAAAAAA TTTGGACCTG CTTTGAATTC TCTATAATCC AGTGCACCGA ACTTATGATG 
GACAGACATC TGGACCAGCT GTTGATGTGT GCCATTTATG TGATGGCAAA GGTCACAAAA 
GAAGACAGGT CCTTCCAGAA CATCATGCGT TGTTACAGAA CTCAGCCACA GGCCCGGAGC 
CAGGTGTACA GAAGTGTCTT GATAAAAGGG AAAAGAAGAA ACTCTGGCAG CAGTGAGAGC 
AGAAGCCATC AGAATTCTCC AACCGAACTA AATACAGACA GAGCCAGTAG AGATTCCAGC 
CCAGTGATGA GGTCAAACAG CACCCTACCA GTTCCACAGC CCAGCAGTGC CCCTCCTACA 
CCAACTCGAC TCACGGGTGC CAGCAGTGAC GTTGAAGAGG AGGAACGAGG AGACCTCATT 
CAGTTCTACA ACAACATCTA TAGGAAGCAA ATCCAAGCGT TTGCCATGAA GTACTCGCAG 
GCAAACGCGC AGACGGACAC TCCTCCCCTC TCTCCCTATC CATTTGTAAG AACAGGCTCC 
CCTCGCCGAG TACAGTTATC TCAAAGTCAT CCTATCTACA TTTCCCCACA TAACAACGAA 
GCAATGCCTT CTCCTCGAGA GAAGATTTTT TACTACTTCA GCAACAGCCC ATCAAAGAGA 
CTGAGGGAAA TCAACAGTAT GATACGGACA GGAGAGACTC CAACTAAAAA GAGAGGGATT 
CTCTTGGACG ACGGAAGTGA ATCACCTGCA AAAAGAATCT GCCCAGAGAA TCACTCTGCT 
CTGTTACGTC GTCTCCAGGA TGTGGCGAAT GACCGAGGTT CACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rbl2 ( NM_001282000.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001268929.1 Mus musculus RB transcriptional corepressor like 2 (Rbl2), transcript variant 2, mRNA.

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CloneID	OMu23256
Clone ID Related Accession (Same CDS sequence)	NM_001282000.1
Accession Version	NM_001282000.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3279bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-20
Organism	Mus musculus(house mouse)
Product	retinoblastoma-like protein 2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY270001.1, AK160027.1, CF736271.1 and AI323872.1. Transcript Variant: This variant (2) lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U47333.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383, SAMN01164138 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCTG GAGGCAACCA GTCGCCACCG CCTCCTCCAG CTGCTGCAGC CAGCTCGGAG 
GAAGAGGAGG AGGATGGCGA CGCCGCGGAT CGCGCGCAGC CCGCGGGGTC CCCGAGCCAT 
CAGATCCAGC AGCGGTTCGA GGAGCTGTGC AGCCGCCTCA ACATGGACGA GGCGGCGCGC 
GCCGAGGCCT GGAGCAGCTA CCGCAGCATG AGCGAGAGCT ACACGCTGGA GGGAAATGAC 
CTTCATTGGT TAGCATGTGC CTTATATGTG GCTTGCAGAA AATCTGTTCC AACTGTGAGC 
AAAGGGACCG CTGAAGGAAA CTATGTATCT TTAACCAGAA TCCTTCGCTG TTCGGAGCAG 
AGCCTAATTG AATTTTTTAA CAAGATGAAG AAGTGGGAAG ACATGGCAAA TCTGCCCCCA 
CATTTCCGAG AACGTACTGA AAGATTAGAA AGAAACTTCA CTGTTTCTGC TGTGATTTTT 
AAGAAATATG AACCCATTTT TCAAGACATT TTTAAATATC CCCAAGAAGA ACAGCCTCGC 
CAGCAAAGAG GAAGAAAACA GAGGCGACAG CCCTGTACCA CATCAGAAAT TTTCCATTTT 
TGCTGGGTGC TTTTTATATA TGCGAAAGGC CTGTCCGAGG ACTGTCACCC CAAGGACTCT 
AAAGCGTCCT CCGACCCGCC GTGTGTCATT GAGAAGCTGT GCTCCTTACA CGACGGTCTA 
GTGTTGGAGG CCAAGGGGAT AAAGGAACAC TTCTGGAAAC CCTATATTAG GAAACTGTTT 
GAGAAAAAGC TTCTCAAGGG GAAGGAAGAA AATCTTACTG GCTTCCTGGA GCCCGGAAAC 
TTTGGAGAGA GTTTTAAGGC CGTTAATAAG GCATATGAAG AATACGTGTT AGCCGCTGGG 
AATCTGGATG AGCGCGTATT CCTTGGTGAG GATGCTGAGG AGGAAGTTGG GACTCTGTCT 
CGGTGTCTAA GTGCTGCCTC AGGTACAGAG AGTGCTGAAC GGACGCAGAT GAGAGACATC 
TTGCAGCAGC ATCTTGACAA GTCTAAAGCA CTTAGAGTCT GCACACCACT GACTGGCGTG 
AGGTATGTTC AGGAGAACAG CCCGTGTGTG ACTCCCGTCT CCACAGCTGC ACACAGCCTG 
AGCCGTCTTC ACACCATGCT GTCCGGCCTC AGGAATGCAC CCAGTGAGAA GCTGGAGCGG 
ATACTCAGGT CATGTTCCCG AGATCCAACT CAGGCTATCG CTGACAGATT GAAAGAAATG 
TACGAAATAT ATTCTCAGCA TTTCCAGCCA GATGAGAATT TTAGTAATTG TGCTAAAGAA 
ATTGCCAACA AACATTTTCG TTTTGCAGAA ATGCTCTACT ATAAAGTATT AGAGTCTGTT 
ATTGAGCAAG AACAAAAAAG ATTGGGAGAC ATGGATTTAT CTGGTGTTCT GGAGCATGAC 
GCATTCCACA GGTCACTCTT GGCCTGCTGC CTTGAGGTGG TCGCTTTTTC CCATAAGCCT 
CCTGGGAATT TTCCATTTAT TGCTGAAATA TTTGATGTAC CACATTATCA TTTTTATAAG 
GTAATTGAAG TATTTATTAG AGCAGAAGAC GGTCTTTGCA GAGAAGTGGT CAAACACCTC 
AATCAGATTG AAGAACAAAT TTTAGACCAT TTGGCATGGA AAACCAAGTC CCCACTGTGG 
GACAGAATTA GAGATAATGA AAACAGAGTC CCTACTTGTG AAGAGGTCAT GCCACCTCAA 
AACCTAGAGA GAACAGATGA AATTTACATC GCTGGCTCTC CCTTAACCCC GAGAAGGGTG 
GGTGAAGTTC GTGCTGATGC TGGAGGACTT GGAAGAAGTA TAACGTCTCC AACCACATTG 
TATGACAGGT ACAGCTCCCC AACAGTCAGC ACTACTAGAA GGCGGCTATT CGAGAATGAT 
AGTCCCTCTG AAGGAAGCAC ATCTGGGCGC ATCCCCCCAC AACCCCTAGT CAACGCTGTC 
CCCGTGCAGA ATGTACCTGG GGAGACTGTT TCTGTCACAC CAGTTCCTGG ACAGACCTTG 
GTCACCATGG CAACAGCCAC TGTCACGGCC AACAATGGAC AAACAGTGAC CATTCCAGTC 
CAAGGTATTG CCAACGAAAA TGGAGGGATA ACCTTCTTCC CAGTCCAAGT CAACGTTGGG 
GGCCAGGCCC AGGCTGTCGC TGGCTCTATC CAGCCCCTCA GTGCTCAAGC ACTGGCTGGA 
AGTCTGAGTT CCCAACAGGT GACAGGAACC ACTTTGCAAG TCCCTGGTCC GGTGGCCATT 
CAACAGATTT CCCCTGGTGG ACAACAGCAG AACCCAGGCC AGCCACTAAC CAGCAGCAGT 
ATCCGGCCGC GGAAGACTAG CTCCTTAGCG CTCTTCTTTA GAAAGGTTTA CTACTTAGCC 
GGTGTCCGCC TTCGAGATCT TTGTATAAAA CTAGATATTT CAGATGAACT GAGGAAAAAA 
ATTTGGACCT GCTTTGAATT CTCTATAATC CAGTGCACCG AACTTATGAT GGACAGACAT 
CTGGACCAGC TGTTGATGTG TGCCATTTAT GTGATGGCAA AGGTCACAAA AGAAGACAGG 
TCCTTCCAGA ACATCATGCG TTGTTACAGA ACTCAGCCAC AGGCCCGGAG CCAGGTGTAC 
AGAAGTGTCT TGATAAAAGG GAAAAGAAGA AACTCTGGCA GCAGTGAGAG CAGAAGCCAT 
CAGAATTCTC CAACCGAACT AAATACAGAC AGAGCCAGTA GAGATTCCAG CCCAGTGATG 
AGGTCAAACA GCACCCTACC AGTTCCACAG CCCAGCAGTG CCCCTCCTAC ACCAACTCGA 
CTCACGGGTG CCAGCAGTGA CGTTGAAGAG GAGGAACGAG GAGACCTCAT TCAGTTCTAC 
AACAACATCT ATAGGAAGCA AATCCAAGCG TTTGCCATGA AGTACTCGCA GGCAAACGCG 
CAGACGGACA CTCCTCCCCT CTCTCCCTAT CCATTTGTAA GAACAGGCTC CCCTCGCCGA 
GTACAGTTAT CTCAAAGTCA TCCTATCTAC ATTTCCCCAC ATAACAACGA AGCAATGCCT 
TCTCCTCGAG AGAAGATTTT TTACTACTTC AGCAACAGCC CATCAAAGAG ACTGAGGGAA 
ATCAACAGTA TGATACGGAC AGGAGAGACT CCAACTAAAA AGAGAGGGAT TCTCTTGGAC 
GACGGAAGTG AATCACCTGC AAAAAGAATC TGCCCAGAGA ATCACTCTGC TCTGTTACGT 
CGTCTCCAGG ATGTGGCGAA TGACCGAGGT TCACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001268929.1
CDS	120..3398
Translation	MASGGNQSPPPPPAAAASSEEEEEDGDAADRAQPAGSPSHQIQQRFEELCSRLNMDEAARAEAWSSYRSMSESYTLEGNDLHWLACALYVACRKSVPTVSKGTAEGNYVSLTRILRCSEQSLIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQQRGRKQRRQPCTTSEIFHFCWVLFIYAKGLSEDCHPKDSKASSDPPCVIEKLCSLHDGLVLEAKGIKEHFWKPYIRKLFEKKLLKGKEENLTGFLEPGNFGESFKAVNKAYEEYVLAAGNLDERVFLGEDAEEEVGTLSRCLSAASGTESAERTQMRDILQQHLDKSKALRVCTPLTGVRYVQENSPCVTPVSTAAHSLSRLHTMLSGLRNAPSEKLERILRSCSRDPTQAIADRLKEMYEIYSQHFQPDENFSNCAKEIANKHFRFAEMLYYKVLESVIEQEQKRLGDMDLSGVLEHDAFHRSLLACCLEVVAFSHKPPGNFPFIAEIFDVPHYHFYKVIEVFIRAEDGLCREVVKHLNQIEEQILDHLAWKTKSPLWDRIRDNENRVPTCEEVMPPQNLERTDEIYIAGSPLTPRRVGEVRADAGGLGRSITSPTTLYDRYSSPTVSTTRRRLFENDSPSEGSTSGRIPPQPLVNAVPVQNVPGETVSVTPVPGQTLVTMATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGGQAQAVAGSIQPLSAQALAGSLSSQQVTGTTLQVPGPVAIQQISPGGQQQNPGQPLTSSSIRPRKTSSLALFFRKVYYLAGVRLRDLCIKLDISDELRKKIWTCFEFSIIQCTELMMDRHLDQLLMCAIYVMAKVTKEDRSFQNIMRCYRTQPQARSQVYRSVLIKGKRRNSGSSESRSHQNSPTELNTDRASRDSSPVMRSNSTLPVPQPSSAPPTPTRLTGASSDVEEEERGDLIQFYNNIYRKQIQAFAMKYSQANAQTDTPPLSPYPFVRTGSPRRVQLSQSHPIYISPHNNEAMPSPREKIFYYFSNSPSKRLREINSMIRTGETPTKKRGILLDDGSESPAKRICPENHSALLRRLQDVANDRGSQ

Target ORF information:

RefSeq Version	NM_001282000.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus RB transcriptional corepressor like 2 (Rbl2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282000.1

ORF Insert Sequence:

ATGGCATCTG GAGGCAACCA GTCGCCACCG CCTCCTCCAG CTGCTGCAGC CAGCTCGGAG 
GAAGAGGAGG AGGATGGCGA CGCCGCGGAT CGCGCGCAGC CCGCGGGGTC CCCGAGCCAT 
CAGATCCAGC AGCGGTTCGA GGAGCTGTGC AGCCGCCTCA ACATGGACGA GGCGGCGCGC 
GCCGAGGCCT GGAGCAGCTA CCGCAGCATG AGCGAGAGCT ACACGCTGGA GGGAAATGAC 
CTTCATTGGT TAGCATGTGC CTTATATGTG GCTTGCAGAA AATCTGTTCC AACTGTGAGC 
AAAGGGACCG CTGAAGGAAA CTATGTATCT TTAACCAGAA TCCTTCGCTG TTCGGAGCAG 
AGCCTAATTG AATTTTTTAA CAAGATGAAG AAGTGGGAAG ACATGGCAAA TCTGCCCCCA 
CATTTCCGAG AACGTACTGA AAGATTAGAA AGAAACTTCA CTGTTTCTGC TGTGATTTTT 
AAGAAATATG AACCCATTTT TCAAGACATT TTTAAATATC CCCAAGAAGA ACAGCCTCGC 
CAGCAAAGAG GAAGAAAACA GAGGCGACAG CCCTGTACCA CATCAGAAAT TTTCCATTTT 
TGCTGGGTGC TTTTTATATA TGCGAAAGGC CTGTCCGAGG ACTGTCACCC CAAGGACTCT 
AAAGCGTCCT CCGACCCGCC GTGTGTCATT GAGAAGCTGT GCTCCTTACA CGACGGTCTA 
GTGTTGGAGG CCAAGGGGAT AAAGGAACAC TTCTGGAAAC CCTATATTAG GAAACTGTTT 
GAGAAAAAGC TTCTCAAGGG GAAGGAAGAA AATCTTACTG GCTTCCTGGA GCCCGGAAAC 
TTTGGAGAGA GTTTTAAGGC CGTTAATAAG GCATATGAAG AATACGTGTT AGCCGCTGGG 
AATCTGGATG AGCGCGTATT CCTTGGTGAG GATGCTGAGG AGGAAGTTGG GACTCTGTCT 
CGGTGTCTAA GTGCTGCCTC AGGTACAGAG AGTGCTGAAC GGACGCAGAT GAGAGACATC 
TTGCAGCAGC ATCTTGACAA GTCTAAAGCA CTTAGAGTCT GCACACCACT GACTGGCGTG 
AGGTATGTTC AGGAGAACAG CCCGTGTGTG ACTCCCGTCT CCACAGCTGC ACACAGCCTG 
AGCCGTCTTC ACACCATGCT GTCCGGCCTC AGGAATGCAC CCAGTGAGAA GCTGGAGCGG 
ATACTCAGGT CATGTTCCCG AGATCCAACT CAGGCTATCG CTGACAGATT GAAAGAAATG 
TACGAAATAT ATTCTCAGCA TTTCCAGCCA GATGAGAATT TTAGTAATTG TGCTAAAGAA 
ATTGCCAACA AACATTTTCG TTTTGCAGAA ATGCTCTACT ATAAAGTATT AGAGTCTGTT 
ATTGAGCAAG AACAAAAAAG ATTGGGAGAC ATGGATTTAT CTGGTGTTCT GGAGCATGAC 
GCATTCCACA GGTCACTCTT GGCCTGCTGC CTTGAGGTGG TCGCTTTTTC CCATAAGCCT 
CCTGGGAATT TTCCATTTAT TGCTGAAATA TTTGATGTAC CACATTATCA TTTTTATAAG 
GTAATTGAAG TATTTATTAG AGCAGAAGAC GGTCTTTGCA GAGAAGTGGT CAAACACCTC 
AATCAGATTG AAGAACAAAT TTTAGACCAT TTGGCATGGA AAACCAAGTC CCCACTGTGG 
GACAGAATTA GAGATAATGA AAACAGAGTC CCTACTTGTG AAGAGGTCAT GCCACCTCAA 
AACCTAGAGA GAACAGATGA AATTTACATC GCTGGCTCTC CCTTAACCCC GAGAAGGGTG 
GGTGAAGTTC GTGCTGATGC TGGAGGACTT GGAAGAAGTA TAACGTCTCC AACCACATTG 
TATGACAGGT ACAGCTCCCC AACAGTCAGC ACTACTAGAA GGCGGCTATT CGAGAATGAT 
AGTCCCTCTG AAGGAAGCAC ATCTGGGCGC ATCCCCCCAC AACCCCTAGT CAACGCTGTC 
CCCGTGCAGA ATGTACCTGG GGAGACTGTT TCTGTCACAC CAGTTCCTGG ACAGACCTTG 
GTCACCATGG CAACAGCCAC TGTCACGGCC AACAATGGAC AAACAGTGAC CATTCCAGTC 
CAAGGTATTG CCAACGAAAA TGGAGGGATA ACCTTCTTCC CAGTCCAAGT CAACGTTGGG 
GGCCAGGCCC AGGCTGTCGC TGGCTCTATC CAGCCCCTCA GTGCTCAAGC ACTGGCTGGA 
AGTCTGAGTT CCCAACAGGT GACAGGAACC ACTTTGCAAG TCCCTGGTCC GGTGGCCATT 
CAACAGATTT CCCCTGGTGG ACAACAGCAG AACCCAGGCC AGCCACTAAC CAGCAGCAGT 
ATCCGGCCGC GGAAGACTAG CTCCTTAGCG CTCTTCTTTA GAAAGGTTTA CTACTTAGCC 
GGTGTCCGCC TTCGAGATCT TTGTATAAAA CTAGATATTT CAGATGAACT GAGGAAAAAA 
ATTTGGACCT GCTTTGAATT CTCTATAATC CAGTGCACCG AACTTATGAT GGACAGACAT 
CTGGACCAGC TGTTGATGTG TGCCATTTAT GTGATGGCAA AGGTCACAAA AGAAGACAGG 
TCCTTCCAGA ACATCATGCG TTGTTACAGA ACTCAGCCAC AGGCCCGGAG CCAGGTGTAC 
AGAAGTGTCT TGATAAAAGG GAAAAGAAGA AACTCTGGCA GCAGTGAGAG CAGAAGCCAT 
CAGAATTCTC CAACCGAACT AAATACAGAC AGAGCCAGTA GAGATTCCAG CCCAGTGATG 
AGGTCAAACA GCACCCTACC AGTTCCACAG CCCAGCAGTG CCCCTCCTAC ACCAACTCGA 
CTCACGGGTG CCAGCAGTGA CGTTGAAGAG GAGGAACGAG GAGACCTCAT TCAGTTCTAC 
AACAACATCT ATAGGAAGCA AATCCAAGCG TTTGCCATGA AGTACTCGCA GGCAAACGCG 
CAGACGGACA CTCCTCCCCT CTCTCCCTAT CCATTTGTAA GAACAGGCTC CCCTCGCCGA 
GTACAGTTAT CTCAAAGTCA TCCTATCTAC ATTTCCCCAC ATAACAACGA AGCAATGCCT 
TCTCCTCGAG AGAAGATTTT TTACTACTTC AGCAACAGCC CATCAAAGAG ACTGAGGGAA 
ATCAACAGTA TGATACGGAC AGGAGAGACT CCAACTAAAA AGAGAGGGAT TCTCTTGGAC 
GACGGAAGTG AATCACCTGC AAAAAGAATC TGCCCAGAGA ATCACTCTGC TCTGTTACGT 
CGTCTCCAGG ATGTGGCGAA TGACCGAGGT TCACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner.
Development (Cambridge, England)145(1)(2018 Jan)
Hwang SH,White KA,Somatilaka BN,Shelton JM,Richardson JA,Mukhopadhyay S

Dnmt1-dependent Chk1 pathway suppression is protective against neuron division.
Development (Cambridge, England)144(18)3303-3314(2017 09)
Oshikawa M,Okada K,Tabata H,Nagata KI,Ajioka I

Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression.
The Journal of experimental medicine214(7)1901-1912(2017 Jul)
Kim E,Cheng Y,Bolton-Gillespie E,Cai X,Ma C,Tarangelo A,Le L,Jambhekar M,Raman P,Hayer KE,Wertheim G,Speck NA,Tong W,Viatour P

CHK1 Inhibition in Small-Cell Lung Cancer Produces Single-Agent Activity in Biomarker-Defined Disease Subsets and Combination Activity with Cisplatin or Olaparib.
Cancer research77(14)3870-3884(2017 Jul)
Sen T,Tong P,Stewart CA,Cristea S,Valliani A,Shames DS,Redwood AB,Fan YH,Li L,Glisson BS,Minna JD,Sage J,Gibbons DL,Piwnica-Worms H,Heymach JV,Wang J,Byers LA

Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer.
Nature545(7654)360-364(2017 05)
Lim JS,Ibaseta A,Fischer MM,Cancilla B,O'Young G,Cristea S,Luca VC,Yang D,Jahchan NS,Hamard C,Antoine M,Wislez M,Kong C,Cain J,Liu YW,Kapoun AM,Garcia KC,Hoey T,Murriel CL,Sage J

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Rbl2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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