Rangap1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rangap1
Entrez Gene ID	19387
Full Name	RAN GTPase activating protein 1
Synonyms	C79654,Fug1,mKIAA1835
General protein information	Preferred Names RAN GTPase activating protein 1 Names ran GTPase-activating protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15 E1\|15 38.21 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_011245524.2	XP_011243826.1	ran GTPase-activating protein 1 isoform X2
NM_001358622.1	NP_001345551.1	ran GTPase-activating protein 1 isoform 2
XM_030248429.1	XP_030104289.1	ran GTPase-activating protein 1 isoform X2
XM_006520646.3	XP_006520709.1	ran GTPase-activating protein 1 isoform X1
NM_001146174.1	NP_001139646.1	ran GTPase-activating protein 1 isoform 1
NM_011241.4	NP_035371.4	ran GTPase-activating protein 1 isoform 1
XM_011245524.3	XP_011243826.1	ran GTPase-activating protein 1 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	RANGAP1	NP_001103559.1
Rattus norvegicus (Norway rat)	Rangap1	NP_001231784.1
Danio rerio (zebrafish)	rangap1a	NP_001070084.1
Danio rerio (zebrafish)	rangap1b	NP_998154.1
Kluyveromyces lactis	KLLA0F25036g	XP_456196.1
Xenopus tropicalis (tropical clawed frog)	rangap1	NP_001116940.1
Homo sapiens (human)	RANGAP1	NP_002874.1
	RANGAP1	XP_002798410.1
Gallus gallus (chicken)	RANGAP1	NP_001006237.1
Magnaporthe oryzae (rice blast fungus)	MGG_01248	XP_003714155.1
Pan troglodytes (chimpanzee)	RANGAP1	XP_003953944.1
Saccharomyces cerevisiae (baker's yeast)	RNA1	NP_013962.1
Eremothecium gossypii	AGOS_AFR525C	NP_986072.1
Neurospora crassa	NCU03207	XP_965307.1
Canis lupus familiaris (dog)	RANGAP1	XP_005625889.1
Mus musculus (house mouse)	Rangap1	NP_035371.4
Schizosaccharomyces pombe (fission yeast)	rna1	NP_594833.1

Gene Ontology
Bibliography

Related articles in PubMed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.
Fujiwara K, Hasegawa K, Oka M, Yoneda Y, Yoshikawa K
Genes to cells : devoted to molecular & cellular mechanisms21(11)1176-1194(2016 Nov)

MYCBP2 Is a Guanosine Exchange Factor for Ran Protein and Determines Its Localization in Neurons of Dorsal Root Ganglia.
D?rr A, Pierre S, Zhang DD, Henke M, Holland S, Scholich K
The Journal of biological chemistry290(42)25620-35(2015 Oct)

The Immune Adaptor SLP-76 Binds to SUMO-RANGAP1 at Nuclear Pore Complex Filaments to Regulate Nuclear Import of Transcription Factors in T Cells.
Liu H, Schneider H, Recino A, Richardson C, Goldberg MW, Rudd CE
Molecular cell59(5)840-9(2015 Sep)

Disruption of SUMO-specific protease 2 induces mitochondria mediated neurodegeneration.
Fu J, Yu HM, Chiu SY, Mirando AJ, Maruyama EO, Cheng JG, Hsu W
PLoS genetics10(10)e1004579(2014 Oct)

Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction.
Kim EY, Chen L, Ma Y, Yu W, Chang J, Moskowitz IP, Wang J
Journal of molecular and cellular cardiology52(3)638-49(2012 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

data suggest that remodeling of the RanGAP-mediated nuclear transport system plays a key role in cell cycle exit for terminal differentiation of cortical neurons
Title: Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

nuclear localization of Ran was strongly increased in MYCBP2-deficient DRGs
Title: MYCBP2 Is a Guanosine Exchange Factor for Ran Protein and Determines Its Localization in Neurons of Dorsal Root Ganglia.

immune cell adaptor SLP-76 binds directly to SUMO-RanGAP1 of cytoplasmic fibrils of the nuclear pore complex, and this interaction is needed for optimal NFATc1 and NF-kappaB p65 nuclear entry in T cells
Title: The Immune Adaptor SLP-76 Binds to SUMO-RANGAP1 at Nuclear Pore Complex Filaments to Regulate Nuclear Import of Transcription Factors in T Cells.

Protection from isopeptidase-mediated deconjugation regulates paralog-selective sumoylation of RanGAP1.
Title: Protection from isopeptidase-mediated deconjugation regulates paralog-selective sumoylation of RanGAP1.

These data suggest a dual function of the Nup358-RanGAP1 complex as a coordinator of importin beta recycling and reformation of novel import complexes.
Title: The Nup358-RanGAP complex is required for efficient importin alpha/beta-dependent nuclear import.

The following Rangap1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rangap1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu07249	NM_011241.4 Latest version!	Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$349.30 $499.00
OMu07249	NM_001146174.1 Latest version!	Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$349.30 $499.00
OMu68587	XM_011245524.3 Latest version!	Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu86670	XM_030248429.1 Latest version!	Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu51085	NM_001358622.1 Latest version!	Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OMu51085	XM_006520646.3 Latest version!	Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OMu68587	XM_011245524.2	Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rangap1 ( NM_001146174.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001139646.1 Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant 2, mRNA.

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CloneID	OMu07249
Clone ID Related Accession (Same CDS sequence)	NM_001146174.1 , NM_011241.4
Accession Version	NM_001146174.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1770bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	ran GTPase-activating protein 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY287991.1, AK159525.1 and BY438103.1. Transcript Variant: This variant (2) differs in the 5' UTR and has multiple coding region differences, compared to variant 3. These differences cause translation initiation at a downstream AUG and result in an isoform (1) with a shorter N-terminus, compared to isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC066213.1, AK042930.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTCTG AAGACATTGC CAAACTGGCA GAGACCCTGG CTAAAACTCA GGTAGCCGGA 
GGGCAGCTGA GTTTTAAGGG CAAGGGTCTC AAACTAAATA CTGCAGAAGA TGCTAAAGAT 
GTGATTAAGG AGATTGAAGA GTTTGACGGC CTCGAAGCTC TACGATTGGA GGGCAACACG 
GTGGGCGTGG AAGCGGCCAG AGTCATCGCC AAGGCCTTAG AGAAGAAGTC TGAGCTGAAG 
CGATGCCACT GGAGTGACAT GTTCACAGGA AGGCTTCGGT CTGAGATCCC ACCAGCTCTG 
ATCTCACTAG GGGAGGGACT CATCACTGCA GGAGCACAGC TGGTGGAACT GGACCTCAGT 
GACAACGCAT TTGGACCCGA TGGAGTGCGA GGCTTCGAGG CCCTCCTCAA GAGCCCAGCC 
TGCTTCACCC TACAGGAACT CAAGCTTAAC AACTGTGGCA TGGGCATCGG GGGTGGCAAG 
ATTCTGGCAG CAGCTCTGAC TGAGTGTCAC CGCAAGTCCA GTGCCCAAGG CAAGCCCCTG 
GCCCTGAAGG TGTTTGTGGC TGGCAGAAAT CGCCTGGAGA ATGACGGAGC CACTGCACTG 
GCAGAAGCTT TTGGGATCAT CGGGACTCTG GAAGAGGTGC ATATGCCACA GAACGGAATT 
AACCATCCTG GTGTCACAGC CCTGGCCCAG GCCTTTGCCA TCAACCCCCT GTTGCGAGTC 
ATCAACCTAA ATGACAACAC CTTCACTGAG AAGGGTGGGG TGGCCATGGC TGAGACTCTG 
AAGACTCTGC GACAAGTGGA AGTGATCAAT TTTGGAGACT GCCTGGTGCG CTCTAAGGGT 
GCCGTTGCCA TCGCAGATGC TGTCCGTGGT GGCCTGCCCA AGCTAAAGGA GCTGAATCTG 
TCGTTCTGCG AAATCAAGAG AGATGCTGCC CTGGTTGTTG CTGAGGCTGT GGCCGACAAG 
GCTGAGCTGG AGAAGCTGGA CCTCAATGGC AATGCCCTCG GAGAAGAGGG CTGTGAGCAG 
CTTCAGGAGG TGATGGACAG CTTCAATATG GCCAAGGTGC TGGCATCCCT CAGTGATGAT 
GAGGGAGAGG ATGAAGATGA GGAGGAAGAA GGAGAAGAGG ATGATGAGGA GGAGGAAGAT 
GAAGAGGATG AGGAAGATGA TGATGAGGAG GAGGAGGAGC AGGAGGAAGA GGAAGAGCCT 
CCGCAGAGAG GGTCAGGGGA GGAGCCGGCT ACACCCTCGA GGAAGATCCT GGACCCTAAC 
AGTGGGGAGC CAGCTCCCGT GCTGTCCTCC CCGACTCCCA CAGACCTCTC CACCTTCCTG 
TCATTCCCCT CCCCAGAGAA GCTGCTGCGT CTGGGTCCCA AGGTCTCGGT GCTGATAGTC 
CAGCAGACTG ATACCTCCGA CCCAGAGAAG GTTGTTTCAG CCTTCCTGAA GGTGGCATCT 
GTGTTCAGGG ATGACGCCTC AGTAAAGACC GCAGTGCTGG ATGCCATCGA TGCCCTCATG 
AAGAAGGCCT TCAGCTGCTC CTCTTTCAAT TCCAACACCT TCCTTACCAG GCTGCTCATC 
CACATGGGTC TGCTCAAGAG TGAAGACAAG ATCAAGGCCA TACCCAGCCT GCATGGCCCC 
CTGATGGTGT TGAACCACGT GGTGAGGCAG GACTATTTCC CCAAGGCCCT TGCACCCCTG 
CTCTTGGCAT TTGTGACAAA GCCCAATGGC GCGCTGGAAA CCTGCTCCTT TGCCCGCCAC 
AATCTGCTGC AGACGCTATA CAACATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139646.1
CDS	244..2013
Translation	MASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSELKRCHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFGIIGTLEEVHMPQNGINHPGVTALAQAFAINPLLRVINLNDNTFTEKGGVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVMDSFNMAKVLASLSDDEGEDEDEEEEGEEDDEEEEDEEDEEDDDEEEEEQEEEEEPPQRGSGEEPATPSRKILDPNSGEPAPVLSSPTPTDLSTFLSFPSPEKLLRLGPKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDDASVKTAVLDAIDALMKKAFSCSSFNSNTFLTRLLIHMGLLKSEDKIKAIPSLHGPLMVLNHVVRQDYFPKALAPLLLAFVTKPNGALETCSFARHNLLQTLYNI

Target ORF information:

RefSeq Version	NM_001146174.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001146174.1

ORF Insert Sequence:

ATGGCCTCTG AAGACATTGC CAAACTGGCA GAGACCCTGG CTAAAACTCA GGTAGCCGGA 
GGGCAGCTGA GTTTTAAGGG CAAGGGTCTC AAACTAAATA CTGCAGAAGA TGCTAAAGAT 
GTGATTAAGG AGATTGAAGA GTTTGACGGC CTCGAAGCTC TACGATTGGA GGGCAACACG 
GTGGGCGTGG AAGCGGCCAG AGTCATCGCC AAGGCCTTAG AGAAGAAGTC TGAGCTGAAG 
CGATGCCACT GGAGTGACAT GTTCACAGGA AGGCTTCGGT CTGAGATCCC ACCAGCTCTG 
ATCTCACTAG GGGAGGGACT CATCACTGCA GGAGCACAGC TGGTGGAACT GGACCTCAGT 
GACAACGCAT TTGGACCCGA TGGAGTGCGA GGCTTCGAGG CCCTCCTCAA GAGCCCAGCC 
TGCTTCACCC TACAGGAACT CAAGCTTAAC AACTGTGGCA TGGGCATCGG GGGTGGCAAG 
ATTCTGGCAG CAGCTCTGAC TGAGTGTCAC CGCAAGTCCA GTGCCCAAGG CAAGCCCCTG 
GCCCTGAAGG TGTTTGTGGC TGGCAGAAAT CGCCTGGAGA ATGACGGAGC CACTGCACTG 
GCAGAAGCTT TTGGGATCAT CGGGACTCTG GAAGAGGTGC ATATGCCACA GAACGGAATT 
AACCATCCTG GTGTCACAGC CCTGGCCCAG GCCTTTGCCA TCAACCCCCT GTTGCGAGTC 
ATCAACCTAA ATGACAACAC CTTCACTGAG AAGGGTGGGG TGGCCATGGC TGAGACTCTG 
AAGACTCTGC GACAAGTGGA AGTGATCAAT TTTGGAGACT GCCTGGTGCG CTCTAAGGGT 
GCCGTTGCCA TCGCAGATGC TGTCCGTGGT GGCCTGCCCA AGCTAAAGGA GCTGAATCTG 
TCGTTCTGCG AAATCAAGAG AGATGCTGCC CTGGTTGTTG CTGAGGCTGT GGCCGACAAG 
GCTGAGCTGG AGAAGCTGGA CCTCAATGGC AATGCCCTCG GAGAAGAGGG CTGTGAGCAG 
CTTCAGGAGG TGATGGACAG CTTCAATATG GCCAAGGTGC TGGCATCCCT CAGTGATGAT 
GAGGGAGAGG ATGAAGATGA GGAGGAAGAA GGAGAAGAGG ATGATGAGGA GGAGGAAGAT 
GAAGAGGATG AGGAAGATGA TGATGAGGAG GAGGAGGAGC AGGAGGAAGA GGAAGAGCCT 
CCGCAGAGAG GGTCAGGGGA GGAGCCGGCT ACACCCTCGA GGAAGATCCT GGACCCTAAC 
AGTGGGGAGC CAGCTCCCGT GCTGTCCTCC CCGACTCCCA CAGACCTCTC CACCTTCCTG 
TCATTCCCCT CCCCAGAGAA GCTGCTGCGT CTGGGTCCCA AGGTCTCGGT GCTGATAGTC 
CAGCAGACTG ATACCTCCGA CCCAGAGAAG GTTGTTTCAG CCTTCCTGAA GGTGGCATCT 
GTGTTCAGGG ATGACGCCTC AGTAAAGACC GCAGTGCTGG ATGCCATCGA TGCCCTCATG 
AAGAAGGCCT TCAGCTGCTC CTCTTTCAAT TCCAACACCT TCCTTACCAG GCTGCTCATC 
CACATGGGTC TGCTCAAGAG TGAAGACAAG ATCAAGGCCA TACCCAGCCT GCATGGCCCC 
CTGATGGTGT TGAACCACGT GGTGAGGCAG GACTATTTCC CCAAGGCCCT TGCACCCCTG 
CTCTTGGCAT TTGTGACAAA GCCCAATGGC GCGCTGGAAA CCTGCTCCTT TGCCCGCCAC 
AATCTGCTGC AGACGCTATA CAACATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rangap1 ( NM_011241.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035371.4 Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu07249
Clone ID Related Accession (Same CDS sequence)	NM_001146174.1 , NM_011241.4
Accession Version	NM_011241.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1770bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	ran GTPase-activating protein 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY287991.1, AK146670.1, AK159525.1 and BY438103.1. On Apr 1, 2009 this sequence version replaced NM_011241.3. Transcript Variant: This variant (1) differs in the 5' UTR and has multiple coding region differences, compared to variant 3. These differences cause translation initiation at a downstream AUG and result in an isoform (1) with a shorter N-terminus, compared to isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK146670.1, SRR1660817.230327.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164138 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTCTG AAGACATTGC CAAACTGGCA GAGACCCTGG CTAAAACTCA GGTAGCCGGA 
GGGCAGCTGA GTTTTAAGGG CAAGGGTCTC AAACTAAATA CTGCAGAAGA TGCTAAAGAT 
GTGATTAAGG AGATTGAAGA GTTTGACGGC CTCGAAGCTC TACGATTGGA GGGCAACACG 
GTGGGCGTGG AAGCGGCCAG AGTCATCGCC AAGGCCTTAG AGAAGAAGTC TGAGCTGAAG 
CGATGCCACT GGAGTGACAT GTTCACAGGA AGGCTTCGGT CTGAGATCCC ACCAGCTCTG 
ATCTCACTAG GGGAGGGACT CATCACTGCA GGAGCACAGC TGGTGGAACT GGACCTCAGT 
GACAACGCAT TTGGACCCGA TGGAGTGCGA GGCTTCGAGG CCCTCCTCAA GAGCCCAGCC 
TGCTTCACCC TACAGGAACT CAAGCTTAAC AACTGTGGCA TGGGCATCGG GGGTGGCAAG 
ATTCTGGCAG CAGCTCTGAC TGAGTGTCAC CGCAAGTCCA GTGCCCAAGG CAAGCCCCTG 
GCCCTGAAGG TGTTTGTGGC TGGCAGAAAT CGCCTGGAGA ATGACGGAGC CACTGCACTG 
GCAGAAGCTT TTGGGATCAT CGGGACTCTG GAAGAGGTGC ATATGCCACA GAACGGAATT 
AACCATCCTG GTGTCACAGC CCTGGCCCAG GCCTTTGCCA TCAACCCCCT GTTGCGAGTC 
ATCAACCTAA ATGACAACAC CTTCACTGAG AAGGGTGGGG TGGCCATGGC TGAGACTCTG 
AAGACTCTGC GACAAGTGGA AGTGATCAAT TTTGGAGACT GCCTGGTGCG CTCTAAGGGT 
GCCGTTGCCA TCGCAGATGC TGTCCGTGGT GGCCTGCCCA AGCTAAAGGA GCTGAATCTG 
TCGTTCTGCG AAATCAAGAG AGATGCTGCC CTGGTTGTTG CTGAGGCTGT GGCCGACAAG 
GCTGAGCTGG AGAAGCTGGA CCTCAATGGC AATGCCCTCG GAGAAGAGGG CTGTGAGCAG 
CTTCAGGAGG TGATGGACAG CTTCAATATG GCCAAGGTGC TGGCATCCCT CAGTGATGAT 
GAGGGAGAGG ATGAAGATGA GGAGGAAGAA GGAGAAGAGG ATGATGAGGA GGAGGAAGAT 
GAAGAGGATG AGGAAGATGA TGATGAGGAG GAGGAGGAGC AGGAGGAAGA GGAAGAGCCT 
CCGCAGAGAG GGTCAGGGGA GGAGCCGGCT ACACCCTCGA GGAAGATCCT GGACCCTAAC 
AGTGGGGAGC CAGCTCCCGT GCTGTCCTCC CCGACTCCCA CAGACCTCTC CACCTTCCTG 
TCATTCCCCT CCCCAGAGAA GCTGCTGCGT CTGGGTCCCA AGGTCTCGGT GCTGATAGTC 
CAGCAGACTG ATACCTCCGA CCCAGAGAAG GTTGTTTCAG CCTTCCTGAA GGTGGCATCT 
GTGTTCAGGG ATGACGCCTC AGTAAAGACC GCAGTGCTGG ATGCCATCGA TGCCCTCATG 
AAGAAGGCCT TCAGCTGCTC CTCTTTCAAT TCCAACACCT TCCTTACCAG GCTGCTCATC 
CACATGGGTC TGCTCAAGAG TGAAGACAAG ATCAAGGCCA TACCCAGCCT GCATGGCCCC 
CTGATGGTGT TGAACCACGT GGTGAGGCAG GACTATTTCC CCAAGGCCCT TGCACCCCTG 
CTCTTGGCAT TTGTGACAAA GCCCAATGGC GCGCTGGAAA CCTGCTCCTT TGCCCGCCAC 
AATCTGCTGC AGACGCTATA CAACATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035371.4
CDS	292..2061
Translation	MASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSELKRCHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFGIIGTLEEVHMPQNGINHPGVTALAQAFAINPLLRVINLNDNTFTEKGGVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVMDSFNMAKVLASLSDDEGEDEDEEEEGEEDDEEEEDEEDEEDDDEEEEEQEEEEEPPQRGSGEEPATPSRKILDPNSGEPAPVLSSPTPTDLSTFLSFPSPEKLLRLGPKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDDASVKTAVLDAIDALMKKAFSCSSFNSNTFLTRLLIHMGLLKSEDKIKAIPSLHGPLMVLNHVVRQDYFPKALAPLLLAFVTKPNGALETCSFARHNLLQTLYNI

Target ORF information:

RefSeq Version	NM_011241.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011241.4

ORF Insert Sequence:

ATGGCCTCTG AAGACATTGC CAAACTGGCA GAGACCCTGG CTAAAACTCA GGTAGCCGGA 
GGGCAGCTGA GTTTTAAGGG CAAGGGTCTC AAACTAAATA CTGCAGAAGA TGCTAAAGAT 
GTGATTAAGG AGATTGAAGA GTTTGACGGC CTCGAAGCTC TACGATTGGA GGGCAACACG 
GTGGGCGTGG AAGCGGCCAG AGTCATCGCC AAGGCCTTAG AGAAGAAGTC TGAGCTGAAG 
CGATGCCACT GGAGTGACAT GTTCACAGGA AGGCTTCGGT CTGAGATCCC ACCAGCTCTG 
ATCTCACTAG GGGAGGGACT CATCACTGCA GGAGCACAGC TGGTGGAACT GGACCTCAGT 
GACAACGCAT TTGGACCCGA TGGAGTGCGA GGCTTCGAGG CCCTCCTCAA GAGCCCAGCC 
TGCTTCACCC TACAGGAACT CAAGCTTAAC AACTGTGGCA TGGGCATCGG GGGTGGCAAG 
ATTCTGGCAG CAGCTCTGAC TGAGTGTCAC CGCAAGTCCA GTGCCCAAGG CAAGCCCCTG 
GCCCTGAAGG TGTTTGTGGC TGGCAGAAAT CGCCTGGAGA ATGACGGAGC CACTGCACTG 
GCAGAAGCTT TTGGGATCAT CGGGACTCTG GAAGAGGTGC ATATGCCACA GAACGGAATT 
AACCATCCTG GTGTCACAGC CCTGGCCCAG GCCTTTGCCA TCAACCCCCT GTTGCGAGTC 
ATCAACCTAA ATGACAACAC CTTCACTGAG AAGGGTGGGG TGGCCATGGC TGAGACTCTG 
AAGACTCTGC GACAAGTGGA AGTGATCAAT TTTGGAGACT GCCTGGTGCG CTCTAAGGGT 
GCCGTTGCCA TCGCAGATGC TGTCCGTGGT GGCCTGCCCA AGCTAAAGGA GCTGAATCTG 
TCGTTCTGCG AAATCAAGAG AGATGCTGCC CTGGTTGTTG CTGAGGCTGT GGCCGACAAG 
GCTGAGCTGG AGAAGCTGGA CCTCAATGGC AATGCCCTCG GAGAAGAGGG CTGTGAGCAG 
CTTCAGGAGG TGATGGACAG CTTCAATATG GCCAAGGTGC TGGCATCCCT CAGTGATGAT 
GAGGGAGAGG ATGAAGATGA GGAGGAAGAA GGAGAAGAGG ATGATGAGGA GGAGGAAGAT 
GAAGAGGATG AGGAAGATGA TGATGAGGAG GAGGAGGAGC AGGAGGAAGA GGAAGAGCCT 
CCGCAGAGAG GGTCAGGGGA GGAGCCGGCT ACACCCTCGA GGAAGATCCT GGACCCTAAC 
AGTGGGGAGC CAGCTCCCGT GCTGTCCTCC CCGACTCCCA CAGACCTCTC CACCTTCCTG 
TCATTCCCCT CCCCAGAGAA GCTGCTGCGT CTGGGTCCCA AGGTCTCGGT GCTGATAGTC 
CAGCAGACTG ATACCTCCGA CCCAGAGAAG GTTGTTTCAG CCTTCCTGAA GGTGGCATCT 
GTGTTCAGGG ATGACGCCTC AGTAAAGACC GCAGTGCTGG ATGCCATCGA TGCCCTCATG 
AAGAAGGCCT TCAGCTGCTC CTCTTTCAAT TCCAACACCT TCCTTACCAG GCTGCTCATC 
CACATGGGTC TGCTCAAGAG TGAAGACAAG ATCAAGGCCA TACCCAGCCT GCATGGCCCC 
CTGATGGTGT TGAACCACGT GGTGAGGCAG GACTATTTCC CCAAGGCCCT TGCACCCCTG 
CTCTTGGCAT TTGTGACAAA GCCCAATGGC GCGCTGGAAA CCTGCTCCTT TGCCCGCCAC 
AATCTGCTGC AGACGCTATA CAACATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rangap1 ( XM_011245524.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011243826.1 Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu68587
Clone ID Related Accession (Same CDS sequence)	XM_011245524.2 , XM_011245524.3
Accession Version	XM_011245524.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1755bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ran GTPase-activating protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011245524.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAGTG GGGTGTTCCT TGGGATGGAT GACCTGGATC CCATAGCCAT CTGTAGCCTG 
TTTGAGGAGT GGGACCCTCA GACAGAGCGC TGCCAAGATG ATCCGCCAGT TTACAGACCT 
GCAGGGGAGC CCGCCACTGC AGCCATGGCC TCTGAAGACA TTGCCAAACT GGCAGAGACC 
CTGGCTAAAA CTCAGGTAGC CGGAGGGCAG CTGAGTTTTA AGGGCAAGGG TCTCAAACTA 
AATACTGCAG AAGATGCTAA AGATGTGATT AAGGAGATTG AAGAGTTTGA CGGCCTCGAA 
GCTCTACGAT TGGAGGGCAA CACGGTGGGC GTGGAAGCGG CCAGAGTCAT CGCCAAGGCC 
TTAGAGAAGA AGTCTGAGCT GAAGCGATGC CACTGGAGTG ACATGTTCAC AGGAAGGCTT 
CGGTCTGAGA TCCCACCAGC TCTGATCTCA CTAGGGGAGG GACTCATCAC TGCAGGAGCA 
CAGCTGGTGG AACTGGACCT CAGTGACAAC GCATTTGGAC CCGATGGAGT GCGAGGCTTC 
GAGGCCCTCC TCAAGAGCCC AGCCTGCTTC ACCCTACAGG AACTCAAGCT TAACAACTGT 
GGCATGGGCA TCGGGGGTGG CAAGATTCTG GCAGCAGCTC TGACTGAGTG TCACCGCAAG 
TCCAGTGCCC AAGGCAAGCC CCTGGCCCTG AAGGTGTTTG TGGCTGGCAG AAATCGCCTG 
GAGAATGACG GAGCCACTGC ACTGGCAGAA GCTTTTGGGA CTCTGAAGAC TCTGCGACAA 
GTGGAAGTGA TCAATTTTGG AGACTGCCTG GTGCGCTCTA AGGGTGCCGT TGCCATCGCA 
GATGCTGTCC GTGGTGGCCT GCCCAAGCTA AAGGAGCTGA ATCTGTCGTT CTGCGAAATC 
AAGAGAGATG CTGCCCTGGT TGTTGCTGAG GCTGTGGCCG ACAAGGCTGA GCTGGAGAAG 
CTGGACCTCA ATGGCAATGC CCTCGGAGAA GAGGGCTGTG AGCAGCTTCA GGAGGTGATG 
GACAGCTTCA ATATGGCCAA GGTGCTGGCA TCCCTCAGTG ATGATGAGGG AGAGGATGAA 
GATGAGGAGG AAGAAGGAGA AGAGGATGAT GAGGAGGAGG AAGATGAAGA GGATGAGGAA 
GATGATGATG AGGAGGAGGA GGAGCAGGAG GAAGAGGAAG AGCCTCCGCA GAGAGGGTCA 
GGGGAGGAGC CGGCTACACC CTCGAGGAAG ATCCTGGACC CTAACAGTGG GGAGCCAGCT 
CCCGTGCTGT CCTCCCCGAC TCCCACAGAC CTCTCCACCT TCCTGTCATT CCCCTCCCCA 
GAGAAGCTGC TGCGTCTGGG TCCCAAGGTC TCGGTGCTGA TAGTCCAGCA GACTGATACC 
TCCGACCCAG AGAAGGTTGT TTCAGCCTTC CTGAAGGTGG CATCTGTGTT CAGGGATGAC 
GCCTCAGTAA AGACCGCAGT GCTGGATGCC ATCGATGCCC TCATGAAGAA GGCCTTCAGC 
TGCTCCTCTT TCAATTCCAA CACCTTCCTT ACCAGGCTGC TCATCCACAT GGGTCTGCTC 
AAGAGTGAAG ACAAGATCAA GGCCATACCC AGCCTGCATG GCCCCCTGAT GGTGTTGAAC 
CACGTGGTGA GGCAGGACTA TTTCCCCAAG GCCCTTGCAC CCCTGCTCTT GGCATTTGTG 
ACAAAGCCCA ATGGCGCGCT GGAAACCTGC TCCTTTGCCC GCCACAATCT GCTGCAGACG 
CTATACAACA TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011243826.1
CDS	101..1855
Translation	MGSGVFLGMDDLDPIAICSLFEEWDPQTERCQDDPPVYRPAGEPATAAMASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSELKRCHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFGTLKTLRQVEVINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVMDSFNMAKVLASLSDDEGEDEDEEEEGEEDDEEEEDEEDEEDDDEEEEEQEEEEEPPQRGSGEEPATPSRKILDPNSGEPAPVLSSPTPTDLSTFLSFPSPEKLLRLGPKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDDASVKTAVLDAIDALMKKAFSCSSFNSNTFLTRLLIHMGLLKSEDKIKAIPSLHGPLMVLNHVVRQDYFPKALAPLLLAFVTKPNGALETCSFARHNLLQTLYNI

Target ORF information:

RefSeq Version	XM_011245524.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011245524.3

ORF Insert Sequence:

ATGGGCAGTG GGGTGTTCCT TGGGATGGAT GACCTGGATC CCATAGCCAT CTGTAGCCTG 
TTTGAGGAGT GGGACCCTCA GACAGAGCGC TGCCAAGATG ATCCGCCAGT TTACAGACCT 
GCAGGGGAGC CCGCCACTGC AGCCATGGCC TCTGAAGACA TTGCCAAACT GGCAGAGACC 
CTGGCTAAAA CTCAGGTAGC CGGAGGGCAG CTGAGTTTTA AGGGCAAGGG TCTCAAACTA 
AATACTGCAG AAGATGCTAA AGATGTGATT AAGGAGATTG AAGAGTTTGA CGGCCTCGAA 
GCTCTACGAT TGGAGGGCAA CACGGTGGGC GTGGAAGCGG CCAGAGTCAT CGCCAAGGCC 
TTAGAGAAGA AGTCTGAGCT GAAGCGATGC CACTGGAGTG ACATGTTCAC AGGAAGGCTT 
CGGTCTGAGA TCCCACCAGC TCTGATCTCA CTAGGGGAGG GACTCATCAC TGCAGGAGCA 
CAGCTGGTGG AACTGGACCT CAGTGACAAC GCATTTGGAC CCGATGGAGT GCGAGGCTTC 
GAGGCCCTCC TCAAGAGCCC AGCCTGCTTC ACCCTACAGG AACTCAAGCT TAACAACTGT 
GGCATGGGCA TCGGGGGTGG CAAGATTCTG GCAGCAGCTC TGACTGAGTG TCACCGCAAG 
TCCAGTGCCC AAGGCAAGCC CCTGGCCCTG AAGGTGTTTG TGGCTGGCAG AAATCGCCTG 
GAGAATGACG GAGCCACTGC ACTGGCAGAA GCTTTTGGGA CTCTGAAGAC TCTGCGACAA 
GTGGAAGTGA TCAATTTTGG AGACTGCCTG GTGCGCTCTA AGGGTGCCGT TGCCATCGCA 
GATGCTGTCC GTGGTGGCCT GCCCAAGCTA AAGGAGCTGA ATCTGTCGTT CTGCGAAATC 
AAGAGAGATG CTGCCCTGGT TGTTGCTGAG GCTGTGGCCG ACAAGGCTGA GCTGGAGAAG 
CTGGACCTCA ATGGCAATGC CCTCGGAGAA GAGGGCTGTG AGCAGCTTCA GGAGGTGATG 
GACAGCTTCA ATATGGCCAA GGTGCTGGCA TCCCTCAGTG ATGATGAGGG AGAGGATGAA 
GATGAGGAGG AAGAAGGAGA AGAGGATGAT GAGGAGGAGG AAGATGAAGA GGATGAGGAA 
GATGATGATG AGGAGGAGGA GGAGCAGGAG GAAGAGGAAG AGCCTCCGCA GAGAGGGTCA 
GGGGAGGAGC CGGCTACACC CTCGAGGAAG ATCCTGGACC CTAACAGTGG GGAGCCAGCT 
CCCGTGCTGT CCTCCCCGAC TCCCACAGAC CTCTCCACCT TCCTGTCATT CCCCTCCCCA 
GAGAAGCTGC TGCGTCTGGG TCCCAAGGTC TCGGTGCTGA TAGTCCAGCA GACTGATACC 
TCCGACCCAG AGAAGGTTGT TTCAGCCTTC CTGAAGGTGG CATCTGTGTT CAGGGATGAC 
GCCTCAGTAA AGACCGCAGT GCTGGATGCC ATCGATGCCC TCATGAAGAA GGCCTTCAGC 
TGCTCCTCTT TCAATTCCAA CACCTTCCTT ACCAGGCTGC TCATCCACAT GGGTCTGCTC 
AAGAGTGAAG ACAAGATCAA GGCCATACCC AGCCTGCATG GCCCCCTGAT GGTGTTGAAC 
CACGTGGTGA GGCAGGACTA TTTCCCCAAG GCCCTTGCAC CCCTGCTCTT GGCATTTGTG 
ACAAAGCCCA ATGGCGCGCT GGAAACCTGC TCCTTTGCCC GCCACAATCT GCTGCAGACG 
CTATACAACA TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rangap1 ( XM_030248429.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030104289.1 Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant X2, mRNA.

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CloneID	OMu86670
Clone ID Related Accession (Same CDS sequence)	XM_030248429.1
Accession Version	XM_030248429.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1611bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ran GTPase-activating protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTCTG AAGACATTGC CAAACTGGCA GAGACCCTGG CTAAAACTCA GGTAGCCGGA 
GGGCAGCTGA GTTTTAAGGG CAAGGGTCTC AAACTAAATA CTGCAGAAGA TGCTAAAGAT 
GTGATTAAGG AGATTGAAGA GTTTGACGGC CTCGAAGCTC TACGATTGGA GGGCAACACG 
GTGGGCGTGG AAGCGGCCAG AGTCATCGCC AAGGCCTTAG AGAAGAAGTC TGAGCTGAAG 
CGATGCCACT GGAGTGACAT GTTCACAGGA AGGCTTCGGT CTGAGATCCC ACCAGCTCTG 
ATCTCACTAG GGGAGGGACT CATCACTGCA GGAGCACAGC TGGTGGAACT GGACCTCAGT 
GACAACGCAT TTGGACCCGA TGGAGTGCGA GGCTTCGAGG CCCTCCTCAA GAGCCCAGCC 
TGCTTCACCC TACAGGAACT CAAGCTTAAC AACTGTGGCA TGGGCATCGG GGGTGGCAAG 
ATTCTGGCAG CAGCTCTGAC TGAGTGTCAC CGCAAGTCCA GTGCCCAAGG CAAGCCCCTG 
GCCCTGAAGG TGTTTGTGGC TGGCAGAAAT CGCCTGGAGA ATGACGGAGC CACTGCACTG 
GCAGAAGCTT TTGGGACTCT GAAGACTCTG CGACAAGTGG AAGTGATCAA TTTTGGAGAC 
TGCCTGGTGC GCTCTAAGGG TGCCGTTGCC ATCGCAGATG CTGTCCGTGG TGGCCTGCCC 
AAGCTAAAGG AGCTGAATCT GTCGTTCTGC GAAATCAAGA GAGATGCTGC CCTGGTTGTT 
GCTGAGGCTG TGGCCGACAA GGCTGAGCTG GAGAAGCTGG ACCTCAATGG CAATGCCCTC 
GGAGAAGAGG GCTGTGAGCA GCTTCAGGAG GTGATGGACA GCTTCAATAT GGCCAAGGTG 
CTGGCATCCC TCAGTGATGA TGAGGGAGAG GATGAAGATG AGGAGGAAGA AGGAGAAGAG 
GATGATGAGG AGGAGGAAGA TGAAGAGGAT GAGGAAGATG ATGATGAGGA GGAGGAGGAG 
CAGGAGGAAG AGGAAGAGCC TCCGCAGAGA GGGTCAGGGG AGGAGCCGGC TACACCCTCG 
AGGAAGATCC TGGACCCTAA CAGTGGGGAG CCAGCTCCCG TGCTGTCCTC CCCGACTCCC 
ACAGACCTCT CCACCTTCCT GTCATTCCCC TCCCCAGAGA AGCTGCTGCG TCTGGGTCCC 
AAGGTCTCGG TGCTGATAGT CCAGCAGACT GATACCTCCG ACCCAGAGAA GGTTGTTTCA 
GCCTTCCTGA AGGTGGCATC TGTGTTCAGG GATGACGCCT CAGTAAAGAC CGCAGTGCTG 
GATGCCATCG ATGCCCTCAT GAAGAAGGCC TTCAGCTGCT CCTCTTTCAA TTCCAACACC 
TTCCTTACCA GGCTGCTCAT CCACATGGGT CTGCTCAAGA GTGAAGACAA GATCAAGGCC 
ATACCCAGCC TGCATGGCCC CCTGATGGTG TTGAACCACG TGGTGAGGCA GGACTATTTC 
CCCAAGGCCC TTGCACCCCT GCTCTTGGCA TTTGTGACAA AGCCCAATGG CGCGCTGGAA 
ACCTGCTCCT TTGCCCGCCA CAATCTGCTG CAGACGCTAT ACAACATCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030104289.1
CDS	1123..2733
Translation	MASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSELKRCHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFGTLKTLRQVEVINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVMDSFNMAKVLASLSDDEGEDEDEEEEGEEDDEEEEDEEDEEDDDEEEEEQEEEEEPPQRGSGEEPATPSRKILDPNSGEPAPVLSSPTPTDLSTFLSFPSPEKLLRLGPKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDDASVKTAVLDAIDALMKKAFSCSSFNSNTFLTRLLIHMGLLKSEDKIKAIPSLHGPLMVLNHVVRQDYFPKALAPLLLAFVTKPNGALETCSFARHNLLQTLYNI

Target ORF information:

RefSeq Version	XM_030248429.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030248429.1

ORF Insert Sequence:

ATGGCCTCTG AAGACATTGC CAAACTGGCA GAGACCCTGG CTAAAACTCA GGTAGCCGGA 
GGGCAGCTGA GTTTTAAGGG CAAGGGTCTC AAACTAAATA CTGCAGAAGA TGCTAAAGAT 
GTGATTAAGG AGATTGAAGA GTTTGACGGC CTCGAAGCTC TACGATTGGA GGGCAACACG 
GTGGGCGTGG AAGCGGCCAG AGTCATCGCC AAGGCCTTAG AGAAGAAGTC TGAGCTGAAG 
CGATGCCACT GGAGTGACAT GTTCACAGGA AGGCTTCGGT CTGAGATCCC ACCAGCTCTG 
ATCTCACTAG GGGAGGGACT CATCACTGCA GGAGCACAGC TGGTGGAACT GGACCTCAGT 
GACAACGCAT TTGGACCCGA TGGAGTGCGA GGCTTCGAGG CCCTCCTCAA GAGCCCAGCC 
TGCTTCACCC TACAGGAACT CAAGCTTAAC AACTGTGGCA TGGGCATCGG GGGTGGCAAG 
ATTCTGGCAG CAGCTCTGAC TGAGTGTCAC CGCAAGTCCA GTGCCCAAGG CAAGCCCCTG 
GCCCTGAAGG TGTTTGTGGC TGGCAGAAAT CGCCTGGAGA ATGACGGAGC CACTGCACTG 
GCAGAAGCTT TTGGGACTCT GAAGACTCTG CGACAAGTGG AAGTGATCAA TTTTGGAGAC 
TGCCTGGTGC GCTCTAAGGG TGCCGTTGCC ATCGCAGATG CTGTCCGTGG TGGCCTGCCC 
AAGCTAAAGG AGCTGAATCT GTCGTTCTGC GAAATCAAGA GAGATGCTGC CCTGGTTGTT 
GCTGAGGCTG TGGCCGACAA GGCTGAGCTG GAGAAGCTGG ACCTCAATGG CAATGCCCTC 
GGAGAAGAGG GCTGTGAGCA GCTTCAGGAG GTGATGGACA GCTTCAATAT GGCCAAGGTG 
CTGGCATCCC TCAGTGATGA TGAGGGAGAG GATGAAGATG AGGAGGAAGA AGGAGAAGAG 
GATGATGAGG AGGAGGAAGA TGAAGAGGAT GAGGAAGATG ATGATGAGGA GGAGGAGGAG 
CAGGAGGAAG AGGAAGAGCC TCCGCAGAGA GGGTCAGGGG AGGAGCCGGC TACACCCTCG 
AGGAAGATCC TGGACCCTAA CAGTGGGGAG CCAGCTCCCG TGCTGTCCTC CCCGACTCCC 
ACAGACCTCT CCACCTTCCT GTCATTCCCC TCCCCAGAGA AGCTGCTGCG TCTGGGTCCC 
AAGGTCTCGG TGCTGATAGT CCAGCAGACT GATACCTCCG ACCCAGAGAA GGTTGTTTCA 
GCCTTCCTGA AGGTGGCATC TGTGTTCAGG GATGACGCCT CAGTAAAGAC CGCAGTGCTG 
GATGCCATCG ATGCCCTCAT GAAGAAGGCC TTCAGCTGCT CCTCTTTCAA TTCCAACACC 
TTCCTTACCA GGCTGCTCAT CCACATGGGT CTGCTCAAGA GTGAAGACAA GATCAAGGCC 
ATACCCAGCC TGCATGGCCC CCTGATGGTG TTGAACCACG TGGTGAGGCA GGACTATTTC 
CCCAAGGCCC TTGCACCCCT GCTCTTGGCA TTTGTGACAA AGCCCAATGG CGCGCTGGAA 
ACCTGCTCCT TTGCCCGCCA CAATCTGCTG CAGACGCTAT ACAACATCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rangap1 ( NM_001358622.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001345551.1 Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant 3, mRNA.

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CloneID	OMu51085
Clone ID Related Accession (Same CDS sequence)	NM_001358622.1 , XM_006520646.3
Accession Version	NM_001358622.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1914bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	ran GTPase-activating protein 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC158970.3 and AC102262.10. On Dec 6, 2017 this sequence version replaced XM_006520646.3. Transcript Variant: This variant (3) encodes the longer isoform (2). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC071200.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGGCAGTG GGGTGTTCCT TGGGATGGAT GACCTGGATC CCATAGCCAT CTGTAGCCTG 
TTTGAGGAGT GGGACCCTCA GACAGAGCGC TGCCAAGATG ATCCGCCAGT TTACAGACCT 
GCAGGGGAGC CCGCCACTGC AGCCATGGCC TCTGAAGACA TTGCCAAACT GGCAGAGACC 
CTGGCTAAAA CTCAGGTAGC CGGAGGGCAG CTGAGTTTTA AGGGCAAGGG TCTCAAACTA 
AATACTGCAG AAGATGCTAA AGATGTGATT AAGGAGATTG AAGAGTTTGA CGGCCTCGAA 
GCTCTACGAT TGGAGGGCAA CACGGTGGGC GTGGAAGCGG CCAGAGTCAT CGCCAAGGCC 
TTAGAGAAGA AGTCTGAGCT GAAGCGATGC CACTGGAGTG ACATGTTCAC AGGAAGGCTT 
CGGTCTGAGA TCCCACCAGC TCTGATCTCA CTAGGGGAGG GACTCATCAC TGCAGGAGCA 
CAGCTGGTGG AACTGGACCT CAGTGACAAC GCATTTGGAC CCGATGGAGT GCGAGGCTTC 
GAGGCCCTCC TCAAGAGCCC AGCCTGCTTC ACCCTACAGG AACTCAAGCT TAACAACTGT 
GGCATGGGCA TCGGGGGTGG CAAGATTCTG GCAGCAGCTC TGACTGAGTG TCACCGCAAG 
TCCAGTGCCC AAGGCAAGCC CCTGGCCCTG AAGGTGTTTG TGGCTGGCAG AAATCGCCTG 
GAGAATGACG GAGCCACTGC ACTGGCAGAA GCTTTTGGGA TCATCGGGAC TCTGGAAGAG 
GTGCATATGC CACAGAACGG AATTAACCAT CCTGGTGTCA CAGCCCTGGC CCAGGCCTTT 
GCCATCAACC CCCTGTTGCG AGTCATCAAC CTAAATGACA ACACCTTCAC TGAGAAGGGT 
GGGGTGGCCA TGGCTGAGAC TCTGAAGACT CTGCGACAAG TGGAAGTGAT CAATTTTGGA 
GACTGCCTGG TGCGCTCTAA GGGTGCCGTT GCCATCGCAG ATGCTGTCCG TGGTGGCCTG 
CCCAAGCTAA AGGAGCTGAA TCTGTCGTTC TGCGAAATCA AGAGAGATGC TGCCCTGGTT 
GTTGCTGAGG CTGTGGCCGA CAAGGCTGAG CTGGAGAAGC TGGACCTCAA TGGCAATGCC 
CTCGGAGAAG AGGGCTGTGA GCAGCTTCAG GAGGTGATGG ACAGCTTCAA TATGGCCAAG 
GTGCTGGCAT CCCTCAGTGA TGATGAGGGA GAGGATGAAG ATGAGGAGGA AGAAGGAGAA 
GAGGATGATG AGGAGGAGGA AGATGAAGAG GATGAGGAAG ATGATGATGA GGAGGAGGAG 
GAGCAGGAGG AAGAGGAAGA GCCTCCGCAG AGAGGGTCAG GGGAGGAGCC GGCTACACCC 
TCGAGGAAGA TCCTGGACCC TAACAGTGGG GAGCCAGCTC CCGTGCTGTC CTCCCCGACT 
CCCACAGACC TCTCCACCTT CCTGTCATTC CCCTCCCCAG AGAAGCTGCT GCGTCTGGGT 
CCCAAGGTCT CGGTGCTGAT AGTCCAGCAG ACTGATACCT CCGACCCAGA GAAGGTTGTT 
TCAGCCTTCC TGAAGGTGGC ATCTGTGTTC AGGGATGACG CCTCAGTAAA GACCGCAGTG 
CTGGATGCCA TCGATGCCCT CATGAAGAAG GCCTTCAGCT GCTCCTCTTT CAATTCCAAC 
ACCTTCCTTA CCAGGCTGCT CATCCACATG GGTCTGCTCA AGAGTGAAGA CAAGATCAAG 
GCCATACCCA GCCTGCATGG CCCCCTGATG GTGTTGAACC ACGTGGTGAG GCAGGACTAT 
TTCCCCAAGG CCCTTGCACC CCTGCTCTTG GCATTTGTGA CAAAGCCCAA TGGCGCGCTG 
GAAACCTGCT CCTTTGCCCG CCACAATCTG CTGCAGACGC TATACAACAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001345551.1
CDS	309..2222
Translation	MGSGVFLGMDDLDPIAICSLFEEWDPQTERCQDDPPVYRPAGEPATAAMASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSELKRCHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFGIIGTLEEVHMPQNGINHPGVTALAQAFAINPLLRVINLNDNTFTEKGGVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVMDSFNMAKVLASLSDDEGEDEDEEEEGEEDDEEEEDEEDEEDDDEEEEEQEEEEEPPQRGSGEEPATPSRKILDPNSGEPAPVLSSPTPTDLSTFLSFPSPEKLLRLGPKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDDASVKTAVLDAIDALMKKAFSCSSFNSNTFLTRLLIHMGLLKSEDKIKAIPSLHGPLMVLNHVVRQDYFPKALAPLLLAFVTKPNGALETCSFARHNLLQTLYNI

Target ORF information:

RefSeq Version	NM_001358622.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001358622.1

ORF Insert Sequence:

ATGGGCAGTG GGGTGTTCCT TGGGATGGAT GACCTGGATC CCATAGCCAT CTGTAGCCTG 
TTTGAGGAGT GGGACCCTCA GACAGAGCGC TGCCAAGATG ATCCGCCAGT TTACAGACCT 
GCAGGGGAGC CCGCCACTGC AGCCATGGCC TCTGAAGACA TTGCCAAACT GGCAGAGACC 
CTGGCTAAAA CTCAGGTAGC CGGAGGGCAG CTGAGTTTTA AGGGCAAGGG TCTCAAACTA 
AATACTGCAG AAGATGCTAA AGATGTGATT AAGGAGATTG AAGAGTTTGA CGGCCTCGAA 
GCTCTACGAT TGGAGGGCAA CACGGTGGGC GTGGAAGCGG CCAGAGTCAT CGCCAAGGCC 
TTAGAGAAGA AGTCTGAGCT GAAGCGATGC CACTGGAGTG ACATGTTCAC AGGAAGGCTT 
CGGTCTGAGA TCCCACCAGC TCTGATCTCA CTAGGGGAGG GACTCATCAC TGCAGGAGCA 
CAGCTGGTGG AACTGGACCT CAGTGACAAC GCATTTGGAC CCGATGGAGT GCGAGGCTTC 
GAGGCCCTCC TCAAGAGCCC AGCCTGCTTC ACCCTACAGG AACTCAAGCT TAACAACTGT 
GGCATGGGCA TCGGGGGTGG CAAGATTCTG GCAGCAGCTC TGACTGAGTG TCACCGCAAG 
TCCAGTGCCC AAGGCAAGCC CCTGGCCCTG AAGGTGTTTG TGGCTGGCAG AAATCGCCTG 
GAGAATGACG GAGCCACTGC ACTGGCAGAA GCTTTTGGGA TCATCGGGAC TCTGGAAGAG 
GTGCATATGC CACAGAACGG AATTAACCAT CCTGGTGTCA CAGCCCTGGC CCAGGCCTTT 
GCCATCAACC CCCTGTTGCG AGTCATCAAC CTAAATGACA ACACCTTCAC TGAGAAGGGT 
GGGGTGGCCA TGGCTGAGAC TCTGAAGACT CTGCGACAAG TGGAAGTGAT CAATTTTGGA 
GACTGCCTGG TGCGCTCTAA GGGTGCCGTT GCCATCGCAG ATGCTGTCCG TGGTGGCCTG 
CCCAAGCTAA AGGAGCTGAA TCTGTCGTTC TGCGAAATCA AGAGAGATGC TGCCCTGGTT 
GTTGCTGAGG CTGTGGCCGA CAAGGCTGAG CTGGAGAAGC TGGACCTCAA TGGCAATGCC 
CTCGGAGAAG AGGGCTGTGA GCAGCTTCAG GAGGTGATGG ACAGCTTCAA TATGGCCAAG 
GTGCTGGCAT CCCTCAGTGA TGATGAGGGA GAGGATGAAG ATGAGGAGGA AGAAGGAGAA 
GAGGATGATG AGGAGGAGGA AGATGAAGAG GATGAGGAAG ATGATGATGA GGAGGAGGAG 
GAGCAGGAGG AAGAGGAAGA GCCTCCGCAG AGAGGGTCAG GGGAGGAGCC GGCTACACCC 
TCGAGGAAGA TCCTGGACCC TAACAGTGGG GAGCCAGCTC CCGTGCTGTC CTCCCCGACT 
CCCACAGACC TCTCCACCTT CCTGTCATTC CCCTCCCCAG AGAAGCTGCT GCGTCTGGGT 
CCCAAGGTCT CGGTGCTGAT AGTCCAGCAG ACTGATACCT CCGACCCAGA GAAGGTTGTT 
TCAGCCTTCC TGAAGGTGGC ATCTGTGTTC AGGGATGACG CCTCAGTAAA GACCGCAGTG 
CTGGATGCCA TCGATGCCCT CATGAAGAAG GCCTTCAGCT GCTCCTCTTT CAATTCCAAC 
ACCTTCCTTA CCAGGCTGCT CATCCACATG GGTCTGCTCA AGAGTGAAGA CAAGATCAAG 
GCCATACCCA GCCTGCATGG CCCCCTGATG GTGTTGAACC ACGTGGTGAG GCAGGACTAT 
TTCCCCAAGG CCCTTGCACC CCTGCTCTTG GCATTTGTGA CAAAGCCCAA TGGCGCGCTG 
GAAACCTGCT CCTTTGCCCG CCACAATCTG CTGCAGACGC TATACAACAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rangap1 ( XM_006520646.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520709.1 Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant X1, mRNA.

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CloneID	OMu51085
Clone ID Related Accession (Same CDS sequence)	NM_001358622.1 , XM_006520646.3
Accession Version	XM_006520646.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1914bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	ran GTPase-activating protein 1 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006520646.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAGTG GGGTGTTCCT TGGGATGGAT GACCTGGATC CCATAGCCAT CTGTAGCCTG 
TTTGAGGAGT GGGACCCTCA GACAGAGCGC TGCCAAGATG ATCCGCCAGT TTACAGACCT 
GCAGGGGAGC CCGCCACTGC AGCCATGGCC TCTGAAGACA TTGCCAAACT GGCAGAGACC 
CTGGCTAAAA CTCAGGTAGC CGGAGGGCAG CTGAGTTTTA AGGGCAAGGG TCTCAAACTA 
AATACTGCAG AAGATGCTAA AGATGTGATT AAGGAGATTG AAGAGTTTGA CGGCCTCGAA 
GCTCTACGAT TGGAGGGCAA CACGGTGGGC GTGGAAGCGG CCAGAGTCAT CGCCAAGGCC 
TTAGAGAAGA AGTCTGAGCT GAAGCGATGC CACTGGAGTG ACATGTTCAC AGGAAGGCTT 
CGGTCTGAGA TCCCACCAGC TCTGATCTCA CTAGGGGAGG GACTCATCAC TGCAGGAGCA 
CAGCTGGTGG AACTGGACCT CAGTGACAAC GCATTTGGAC CCGATGGAGT GCGAGGCTTC 
GAGGCCCTCC TCAAGAGCCC AGCCTGCTTC ACCCTACAGG AACTCAAGCT TAACAACTGT 
GGCATGGGCA TCGGGGGTGG CAAGATTCTG GCAGCAGCTC TGACTGAGTG TCACCGCAAG 
TCCAGTGCCC AAGGCAAGCC CCTGGCCCTG AAGGTGTTTG TGGCTGGCAG AAATCGCCTG 
GAGAATGACG GAGCCACTGC ACTGGCAGAA GCTTTTGGGA TCATCGGGAC TCTGGAAGAG 
GTGCATATGC CACAGAACGG AATTAACCAT CCTGGTGTCA CAGCCCTGGC CCAGGCCTTT 
GCCATCAACC CCCTGTTGCG AGTCATCAAC CTAAATGACA ACACCTTCAC TGAGAAGGGT 
GGGGTGGCCA TGGCTGAGAC TCTGAAGACT CTGCGACAAG TGGAAGTGAT CAATTTTGGA 
GACTGCCTGG TGCGCTCTAA GGGTGCCGTT GCCATCGCAG ATGCTGTCCG TGGTGGCCTG 
CCCAAGCTAA AGGAGCTGAA TCTGTCGTTC TGCGAAATCA AGAGAGATGC TGCCCTGGTT 
GTTGCTGAGG CTGTGGCCGA CAAGGCTGAG CTGGAGAAGC TGGACCTCAA TGGCAATGCC 
CTCGGAGAAG AGGGCTGTGA GCAGCTTCAG GAGGTGATGG ACAGCTTCAA TATGGCCAAG 
GTGCTGGCAT CCCTCAGTGA TGATGAGGGA GAGGATGAAG ATGAGGAGGA AGAAGGAGAA 
GAGGATGATG AGGAGGAGGA AGATGAAGAG GATGAGGAAG ATGATGATGA GGAGGAGGAG 
GAGCAGGAGG AAGAGGAAGA GCCTCCGCAG AGAGGGTCAG GGGAGGAGCC GGCTACACCC 
TCGAGGAAGA TCCTGGACCC TAACAGTGGG GAGCCAGCTC CCGTGCTGTC CTCCCCGACT 
CCCACAGACC TCTCCACCTT CCTGTCATTC CCCTCCCCAG AGAAGCTGCT GCGTCTGGGT 
CCCAAGGTCT CGGTGCTGAT AGTCCAGCAG ACTGATACCT CCGACCCAGA GAAGGTTGTT 
TCAGCCTTCC TGAAGGTGGC ATCTGTGTTC AGGGATGACG CCTCAGTAAA GACCGCAGTG 
CTGGATGCCA TCGATGCCCT CATGAAGAAG GCCTTCAGCT GCTCCTCTTT CAATTCCAAC 
ACCTTCCTTA CCAGGCTGCT CATCCACATG GGTCTGCTCA AGAGTGAAGA CAAGATCAAG 
GCCATACCCA GCCTGCATGG CCCCCTGATG GTGTTGAACC ACGTGGTGAG GCAGGACTAT 
TTCCCCAAGG CCCTTGCACC CCTGCTCTTG GCATTTGTGA CAAAGCCCAA TGGCGCGCTG 
GAAACCTGCT CCTTTGCCCG CCACAATCTG CTGCAGACGC TATACAACAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520709.1
CDS	100..2013
Translation	MGSGVFLGMDDLDPIAICSLFEEWDPQTERCQDDPPVYRPAGEPATAAMASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSELKRCHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFGIIGTLEEVHMPQNGINHPGVTALAQAFAINPLLRVINLNDNTFTEKGGVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVMDSFNMAKVLASLSDDEGEDEDEEEEGEEDDEEEEDEEDEEDDDEEEEEQEEEEEPPQRGSGEEPATPSRKILDPNSGEPAPVLSSPTPTDLSTFLSFPSPEKLLRLGPKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDDASVKTAVLDAIDALMKKAFSCSSFNSNTFLTRLLIHMGLLKSEDKIKAIPSLHGPLMVLNHVVRQDYFPKALAPLLLAFVTKPNGALETCSFARHNLLQTLYNI

Target ORF information:

RefSeq Version	XM_006520646.3
Organism	Mus musculus(House mouse)
Definition	Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520646.3

ORF Insert Sequence:

ATGGGCAGTG GGGTGTTCCT TGGGATGGAT GACCTGGATC CCATAGCCAT CTGTAGCCTG 
TTTGAGGAGT GGGACCCTCA GACAGAGCGC TGCCAAGATG ATCCGCCAGT TTACAGACCT 
GCAGGGGAGC CCGCCACTGC AGCCATGGCC TCTGAAGACA TTGCCAAACT GGCAGAGACC 
CTGGCTAAAA CTCAGGTAGC CGGAGGGCAG CTGAGTTTTA AGGGCAAGGG TCTCAAACTA 
AATACTGCAG AAGATGCTAA AGATGTGATT AAGGAGATTG AAGAGTTTGA CGGCCTCGAA 
GCTCTACGAT TGGAGGGCAA CACGGTGGGC GTGGAAGCGG CCAGAGTCAT CGCCAAGGCC 
TTAGAGAAGA AGTCTGAGCT GAAGCGATGC CACTGGAGTG ACATGTTCAC AGGAAGGCTT 
CGGTCTGAGA TCCCACCAGC TCTGATCTCA CTAGGGGAGG GACTCATCAC TGCAGGAGCA 
CAGCTGGTGG AACTGGACCT CAGTGACAAC GCATTTGGAC CCGATGGAGT GCGAGGCTTC 
GAGGCCCTCC TCAAGAGCCC AGCCTGCTTC ACCCTACAGG AACTCAAGCT TAACAACTGT 
GGCATGGGCA TCGGGGGTGG CAAGATTCTG GCAGCAGCTC TGACTGAGTG TCACCGCAAG 
TCCAGTGCCC AAGGCAAGCC CCTGGCCCTG AAGGTGTTTG TGGCTGGCAG AAATCGCCTG 
GAGAATGACG GAGCCACTGC ACTGGCAGAA GCTTTTGGGA TCATCGGGAC TCTGGAAGAG 
GTGCATATGC CACAGAACGG AATTAACCAT CCTGGTGTCA CAGCCCTGGC CCAGGCCTTT 
GCCATCAACC CCCTGTTGCG AGTCATCAAC CTAAATGACA ACACCTTCAC TGAGAAGGGT 
GGGGTGGCCA TGGCTGAGAC TCTGAAGACT CTGCGACAAG TGGAAGTGAT CAATTTTGGA 
GACTGCCTGG TGCGCTCTAA GGGTGCCGTT GCCATCGCAG ATGCTGTCCG TGGTGGCCTG 
CCCAAGCTAA AGGAGCTGAA TCTGTCGTTC TGCGAAATCA AGAGAGATGC TGCCCTGGTT 
GTTGCTGAGG CTGTGGCCGA CAAGGCTGAG CTGGAGAAGC TGGACCTCAA TGGCAATGCC 
CTCGGAGAAG AGGGCTGTGA GCAGCTTCAG GAGGTGATGG ACAGCTTCAA TATGGCCAAG 
GTGCTGGCAT CCCTCAGTGA TGATGAGGGA GAGGATGAAG ATGAGGAGGA AGAAGGAGAA 
GAGGATGATG AGGAGGAGGA AGATGAAGAG GATGAGGAAG ATGATGATGA GGAGGAGGAG 
GAGCAGGAGG AAGAGGAAGA GCCTCCGCAG AGAGGGTCAG GGGAGGAGCC GGCTACACCC 
TCGAGGAAGA TCCTGGACCC TAACAGTGGG GAGCCAGCTC CCGTGCTGTC CTCCCCGACT 
CCCACAGACC TCTCCACCTT CCTGTCATTC CCCTCCCCAG AGAAGCTGCT GCGTCTGGGT 
CCCAAGGTCT CGGTGCTGAT AGTCCAGCAG ACTGATACCT CCGACCCAGA GAAGGTTGTT 
TCAGCCTTCC TGAAGGTGGC ATCTGTGTTC AGGGATGACG CCTCAGTAAA GACCGCAGTG 
CTGGATGCCA TCGATGCCCT CATGAAGAAG GCCTTCAGCT GCTCCTCTTT CAATTCCAAC 
ACCTTCCTTA CCAGGCTGCT CATCCACATG GGTCTGCTCA AGAGTGAAGA CAAGATCAAG 
GCCATACCCA GCCTGCATGG CCCCCTGATG GTGTTGAACC ACGTGGTGAG GCAGGACTAT 
TTCCCCAAGG CCCTTGCACC CCTGCTCTTG GCATTTGTGA CAAAGCCCAA TGGCGCGCTG 
GAAACCTGCT CCTTTGCCCG CCACAATCTG CTGCAGACGC TATACAACAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rangap1 ( XM_011245524.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011243826.1 Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant X2, mRNA.

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CloneID	OMu68587
Clone ID Related Accession (Same CDS sequence)	XM_011245524.2 , XM_011245524.3
Accession Version	XM_011245524.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1755bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	ran GTPase-activating protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011245524.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAGTG GGGTGTTCCT TGGGATGGAT GACCTGGATC CCATAGCCAT CTGTAGCCTG 
TTTGAGGAGT GGGACCCTCA GACAGAGCGC TGCCAAGATG ATCCGCCAGT TTACAGACCT 
GCAGGGGAGC CCGCCACTGC AGCCATGGCC TCTGAAGACA TTGCCAAACT GGCAGAGACC 
CTGGCTAAAA CTCAGGTAGC CGGAGGGCAG CTGAGTTTTA AGGGCAAGGG TCTCAAACTA 
AATACTGCAG AAGATGCTAA AGATGTGATT AAGGAGATTG AAGAGTTTGA CGGCCTCGAA 
GCTCTACGAT TGGAGGGCAA CACGGTGGGC GTGGAAGCGG CCAGAGTCAT CGCCAAGGCC 
TTAGAGAAGA AGTCTGAGCT GAAGCGATGC CACTGGAGTG ACATGTTCAC AGGAAGGCTT 
CGGTCTGAGA TCCCACCAGC TCTGATCTCA CTAGGGGAGG GACTCATCAC TGCAGGAGCA 
CAGCTGGTGG AACTGGACCT CAGTGACAAC GCATTTGGAC CCGATGGAGT GCGAGGCTTC 
GAGGCCCTCC TCAAGAGCCC AGCCTGCTTC ACCCTACAGG AACTCAAGCT TAACAACTGT 
GGCATGGGCA TCGGGGGTGG CAAGATTCTG GCAGCAGCTC TGACTGAGTG TCACCGCAAG 
TCCAGTGCCC AAGGCAAGCC CCTGGCCCTG AAGGTGTTTG TGGCTGGCAG AAATCGCCTG 
GAGAATGACG GAGCCACTGC ACTGGCAGAA GCTTTTGGGA CTCTGAAGAC TCTGCGACAA 
GTGGAAGTGA TCAATTTTGG AGACTGCCTG GTGCGCTCTA AGGGTGCCGT TGCCATCGCA 
GATGCTGTCC GTGGTGGCCT GCCCAAGCTA AAGGAGCTGA ATCTGTCGTT CTGCGAAATC 
AAGAGAGATG CTGCCCTGGT TGTTGCTGAG GCTGTGGCCG ACAAGGCTGA GCTGGAGAAG 
CTGGACCTCA ATGGCAATGC CCTCGGAGAA GAGGGCTGTG AGCAGCTTCA GGAGGTGATG 
GACAGCTTCA ATATGGCCAA GGTGCTGGCA TCCCTCAGTG ATGATGAGGG AGAGGATGAA 
GATGAGGAGG AAGAAGGAGA AGAGGATGAT GAGGAGGAGG AAGATGAAGA GGATGAGGAA 
GATGATGATG AGGAGGAGGA GGAGCAGGAG GAAGAGGAAG AGCCTCCGCA GAGAGGGTCA 
GGGGAGGAGC CGGCTACACC CTCGAGGAAG ATCCTGGACC CTAACAGTGG GGAGCCAGCT 
CCCGTGCTGT CCTCCCCGAC TCCCACAGAC CTCTCCACCT TCCTGTCATT CCCCTCCCCA 
GAGAAGCTGC TGCGTCTGGG TCCCAAGGTC TCGGTGCTGA TAGTCCAGCA GACTGATACC 
TCCGACCCAG AGAAGGTTGT TTCAGCCTTC CTGAAGGTGG CATCTGTGTT CAGGGATGAC 
GCCTCAGTAA AGACCGCAGT GCTGGATGCC ATCGATGCCC TCATGAAGAA GGCCTTCAGC 
TGCTCCTCTT TCAATTCCAA CACCTTCCTT ACCAGGCTGC TCATCCACAT GGGTCTGCTC 
AAGAGTGAAG ACAAGATCAA GGCCATACCC AGCCTGCATG GCCCCCTGAT GGTGTTGAAC 
CACGTGGTGA GGCAGGACTA TTTCCCCAAG GCCCTTGCAC CCCTGCTCTT GGCATTTGTG 
ACAAAGCCCA ATGGCGCGCT GGAAACCTGC TCCTTTGCCC GCCACAATCT GCTGCAGACG 
CTATACAACA TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011243826.1
CDS	100..1854
Translation	MGSGVFLGMDDLDPIAICSLFEEWDPQTERCQDDPPVYRPAGEPATAAMASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSELKRCHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFGTLKTLRQVEVINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVMDSFNMAKVLASLSDDEGEDEDEEEEGEEDDEEEEDEEDEEDDDEEEEEQEEEEEPPQRGSGEEPATPSRKILDPNSGEPAPVLSSPTPTDLSTFLSFPSPEKLLRLGPKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDDASVKTAVLDAIDALMKKAFSCSSFNSNTFLTRLLIHMGLLKSEDKIKAIPSLHGPLMVLNHVVRQDYFPKALAPLLLAFVTKPNGALETCSFARHNLLQTLYNI

Target ORF information:

RefSeq Version	XM_011245524.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus RAN GTPase activating protein 1 (Rangap1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011245524.2

ORF Insert Sequence:

ATGGGCAGTG GGGTGTTCCT TGGGATGGAT GACCTGGATC CCATAGCCAT CTGTAGCCTG 
TTTGAGGAGT GGGACCCTCA GACAGAGCGC TGCCAAGATG ATCCGCCAGT TTACAGACCT 
GCAGGGGAGC CCGCCACTGC AGCCATGGCC TCTGAAGACA TTGCCAAACT GGCAGAGACC 
CTGGCTAAAA CTCAGGTAGC CGGAGGGCAG CTGAGTTTTA AGGGCAAGGG TCTCAAACTA 
AATACTGCAG AAGATGCTAA AGATGTGATT AAGGAGATTG AAGAGTTTGA CGGCCTCGAA 
GCTCTACGAT TGGAGGGCAA CACGGTGGGC GTGGAAGCGG CCAGAGTCAT CGCCAAGGCC 
TTAGAGAAGA AGTCTGAGCT GAAGCGATGC CACTGGAGTG ACATGTTCAC AGGAAGGCTT 
CGGTCTGAGA TCCCACCAGC TCTGATCTCA CTAGGGGAGG GACTCATCAC TGCAGGAGCA 
CAGCTGGTGG AACTGGACCT CAGTGACAAC GCATTTGGAC CCGATGGAGT GCGAGGCTTC 
GAGGCCCTCC TCAAGAGCCC AGCCTGCTTC ACCCTACAGG AACTCAAGCT TAACAACTGT 
GGCATGGGCA TCGGGGGTGG CAAGATTCTG GCAGCAGCTC TGACTGAGTG TCACCGCAAG 
TCCAGTGCCC AAGGCAAGCC CCTGGCCCTG AAGGTGTTTG TGGCTGGCAG AAATCGCCTG 
GAGAATGACG GAGCCACTGC ACTGGCAGAA GCTTTTGGGA CTCTGAAGAC TCTGCGACAA 
GTGGAAGTGA TCAATTTTGG AGACTGCCTG GTGCGCTCTA AGGGTGCCGT TGCCATCGCA 
GATGCTGTCC GTGGTGGCCT GCCCAAGCTA AAGGAGCTGA ATCTGTCGTT CTGCGAAATC 
AAGAGAGATG CTGCCCTGGT TGTTGCTGAG GCTGTGGCCG ACAAGGCTGA GCTGGAGAAG 
CTGGACCTCA ATGGCAATGC CCTCGGAGAA GAGGGCTGTG AGCAGCTTCA GGAGGTGATG 
GACAGCTTCA ATATGGCCAA GGTGCTGGCA TCCCTCAGTG ATGATGAGGG AGAGGATGAA 
GATGAGGAGG AAGAAGGAGA AGAGGATGAT GAGGAGGAGG AAGATGAAGA GGATGAGGAA 
GATGATGATG AGGAGGAGGA GGAGCAGGAG GAAGAGGAAG AGCCTCCGCA GAGAGGGTCA 
GGGGAGGAGC CGGCTACACC CTCGAGGAAG ATCCTGGACC CTAACAGTGG GGAGCCAGCT 
CCCGTGCTGT CCTCCCCGAC TCCCACAGAC CTCTCCACCT TCCTGTCATT CCCCTCCCCA 
GAGAAGCTGC TGCGTCTGGG TCCCAAGGTC TCGGTGCTGA TAGTCCAGCA GACTGATACC 
TCCGACCCAG AGAAGGTTGT TTCAGCCTTC CTGAAGGTGG CATCTGTGTT CAGGGATGAC 
GCCTCAGTAA AGACCGCAGT GCTGGATGCC ATCGATGCCC TCATGAAGAA GGCCTTCAGC 
TGCTCCTCTT TCAATTCCAA CACCTTCCTT ACCAGGCTGC TCATCCACAT GGGTCTGCTC 
AAGAGTGAAG ACAAGATCAA GGCCATACCC AGCCTGCATG GCCCCCTGAT GGTGTTGAAC 
CACGTGGTGA GGCAGGACTA TTTCCCCAAG GCCCTTGCAC CCCTGCTCTT GGCATTTGTG 
ACAAAGCCCA ATGGCGCGCT GGAAACCTGC TCCTTTGCCC GCCACAATCT GCTGCAGACG 
CTATACAACA TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.
Genes to cells : devoted to molecular & cellular mechanisms21(11)1176-1194(2016 Nov)
Fujiwara K,Hasegawa K,Oka M,Yoneda Y,Yoshikawa K

MYCBP2 Is a Guanosine Exchange Factor for Ran Protein and Determines Its Localization in Neurons of Dorsal Root Ganglia.
The Journal of biological chemistry290(42)25620-35(2015 Oct)
D?rr A,Pierre S,Zhang DD,Henke M,Holland S,Scholich K

The Immune Adaptor SLP-76 Binds to SUMO-RANGAP1 at Nuclear Pore Complex Filaments to Regulate Nuclear Import of Transcription Factors in T Cells.
Molecular cell59(5)840-9(2015 Sep)
Liu H,Schneider H,Recino A,Richardson C,Goldberg MW,Rudd CE

Disruption of SUMO-specific protease 2 induces mitochondria mediated neurodegeneration.
PLoS genetics10(10)e1004579(2014 Oct)
Fu J,Yu HM,Chiu SY,Mirando AJ,Maruyama EO,Cheng JG,Hsu W

Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction.
Journal of molecular and cellular cardiology52(3)638-49(2012 Mar)
Kim EY,Chen L,Ma Y,Yu W,Chang J,Moskowitz IP,Wang J

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Rangap1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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