gRNAs
The following Ranbp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ranbp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu18826 | |
| Clone ID Related Accession (Same CDS sequence) | NM_011240.3 | |
| Accession Version | NM_011240.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 9162bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-26 | |
| Organism | Mus musculus(house mouse) | |
| Product | E3 SUMO-protein ligase RanBP2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC158593.8. On Jul 25, 2007 this sequence version replaced NM_011240.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849383 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGAGGCGTA GCAAGGCCGA CGTGGAGCGG TACATCGCCT CGGTGCAGGG CTCCGCCCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_035370.2 |
| CDS | 129..9290 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_011240.3 |
1 | ATGAGGCGTA GCAAGGCCGA CGTGGAGCGG TACATCGCCT CGGTGCAGGG CTCCGCCCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes. |
Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes. |
High-throughput discovery of novel developmental phenotypes. |
Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis. |
