Ptpro cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ptpro
Entrez Gene ID	19277
Full Name	protein tyrosine phosphatase, receptor type, O
Synonyms	D28,GLEPP1,PTPBK,PTPROt,PTPU2,PTPoc,PTPphi,Ptpn15,R-PTP-O
General protein information	Preferred Names protein tyrosine phosphatase, receptor type, O Names receptor-type tyrosine-protein phosphatase O PTPase U2 glomerular epithelial protein 1 protein tyrosine phosphatase U2 protein tyrosine phosphatase, non-receptor type 15 receptor protein tyrosine phosphatase RO
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 G1

mRNA and Protein(s)

mRNA	Protein	Name
XM_030255238.1	XP_030111098.1	receptor-type tyrosine-protein phosphatase O isoform X1
NM_001164402.1	NP_001157874.1	receptor-type tyrosine-protein phosphatase O isoform 3
NM_001164403.1	NP_001157875.1	receptor-type tyrosine-protein phosphatase O isoform 4
NM_011216.3	NP_035346.3	receptor-type tyrosine-protein phosphatase O isoform 1 precursor
NM_001164401.1	NP_001157873.1	receptor-type tyrosine-protein phosphatase O isoform 2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	PTPRO	NP_109592.1
Bos taurus (cattle)	PTPRO	XP_002687817.3
Rattus norvegicus (Norway rat)	Ptpro	NP_059032.1
Pan troglodytes (chimpanzee)	PTPRO	XP_003313570.2
Mus musculus (house mouse)	Ptpro	NP_035346.3
Danio rerio (zebrafish)	ptpro	NP_001077283.1
Canis lupus familiaris (dog)	PTPRO	XP_543791.3
Gallus gallus (chicken)	PTPRO	NP_989453.1

Gene Ontology
Bibliography

Related articles in PubMed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstr?m E, Pachnis V, Marklund U
Gastroenterology(2017 Oct)

Identification of Protein Tyrosine Phosphatase Receptor Type O (PTPRO) as a Synaptic Adhesion Molecule that Promotes Synapse Formation.
Jiang W, Wei M, Liu M, Pan Y, Cao D, Yang X, Zhang C
The Journal of neuroscience : the official journal of the Society for Neuroscience37(41)9828-9843(2017 Oct)

The PTPROt tyrosine phosphatase functions as an obligate haploinsufficient tumor suppressor in vivo in B-cell chronic lymphocytic leukemia.
Wakim J, Arman E, Becker-Herman S, Kramer MP, Bakos E, Shachar I, Elson A
Oncogene36(26)3686-3694(2017 Jun)

PTPRO Promotes Oxidized Low-Density Lipoprotein Induced Oxidative Stress and Cell Apoptosis through Toll-Like Receptor 4/Nuclear Factor ?B Pathway.
Liang C, Wang X, Hu J, Lian X, Zhu T, Zhang H, Gu N, Li J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology42(2)495-505(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Using loss-of-function and gain-of-function approaches, we show that PTPRO promotes the formation of excitatory synapses
Title: Identification of Protein Tyrosine Phosphatase Receptor Type O (PTPRO) as a Synaptic Adhesion Molecule that Promotes Synapse Formation.

PTPROt thus functions as an obligate haploinsufficient TS in CLL, where its expression levels determine its role as a promoter or inhibitor of the tumorigenic process in mice. Partial loss of PTPROt generates the strongest disease phenotype, suggesting that its intermediate expression levels in CLL are selected for.
Title: The PTPROt tyrosine phosphatase functions as an obligate haploinsufficient tumor suppressor in vivo in B-cell chronic lymphocytic leukemia.

TLR4 and NF-kappaB/p65 phosphorylation was significantly enhanced in PTPRO over-expressing cells, while significantly down-regulated in PTPRO knockout cells. PTPRO plays ital roles in atherosclerosis (AS) via promoting ox-LDL induced oxidative stress and cell apoptosis through TLR4/NF-kappaB pathway.
Title: PTPRO Promotes Oxidized Low-Density Lipoprotein Induced Oxidative Stress and Cell Apoptosis through Toll-Like Receptor 4/Nuclear Factor ?B Pathway.

PTPRO truncated serves as an important tumor suppressor in hepatocellular carcinoma microenvironment.
Title: PTPROt maintains T cell immunity in the microenvironment of hepatocellular carcinoma.

PTPRO plays an important role in FH by interacting with TLR4.
Title: Aggravated Liver Injury but Attenuated Inflammation in PTPRO-Deficient Mice Following LPS/D-GaIN Induced Fulminant Hepatitis.

The following Ptpro gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ptpro cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu09784	NM_001164402.1 Latest version!	Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$440.30 $629.00
OMu09786	NM_001164403.1 Latest version!	Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu89155	XM_030255238.1 Latest version!	Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OMu07707	NM_011216.3 Latest version!	Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00
OMu09782	NM_001164401.1 Latest version!	Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ptpro ( NM_001164402.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001157874.1 Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu09784
Clone ID Related Accession (Same CDS sequence)	NM_001164402.1
Accession Version	NM_001164402.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1218bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Mus musculus(house mouse)
Product	receptor-type tyrosine-protein phosphatase O isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC163627.4, AC093120.4 and AW490226.1. Transcript Variant: This variant (3) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences causes translation initiation at a downstream AUG, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U37465.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTTACAG AGGTGAACCC TAACGTGGTG GTGATCTCGG TGCTGGCCAT CCTCAGCACA 
CTTTTAATTG GACTGCTCTT AGTGACCCTT GTCATTCTCC GAAAGAAGCA CCTGCAGATG 
GCTAGGGAAT GTGGAGCTGG CACGTTTGTT AACTTTGCAT CCTTAGAAAG GGAAGGGAAA 
CTCCCCTACA GTTGGCGTAG GAGTGTGTTT GCTCTCTTAA CCCTGCTGCC TTCATGTCTT 
TGGACTGACT ATCTTTTGGC ATTTTATATT AACCCTTGGA GTAAAAATGG CTTAAAGAAG 
AGGAAACTAA CAAACCCCGT TCAGCTGGAT GACTTCGATT CTTACATCAA GGATATGGCC 
AAGGACTCGG ACTATAAATT CTCTCTTCAG TTTGAGGAGT TGAAGTTGAT TGGACTGGAT 
ATTCCGCACT TTGCTGCAGA TCTACCGCTG AACCGATGTA AAAACCGCTA CACAAACATC 
CTGCCGTATG ACTTTAGCCG GGTGAGGCTA GTCTCCATGA ACGAAGAGGA AGGAGCAGAC 
TACATTAATG CCAACTATAT TCCTGGATAC AACTCACCCC AGGAGTACAT TGCCACCCAG 
GGTCCCCTGC CAGAAACCAG AAATGACTTC TGGAAGATGG TCCTACAACA GAAGTCCCAC 
ATCATCGTCA TGCTCACTCA ATGCAATGAG AAAAGGAGGG TAAAATGTGA CCACTACTGG 
CCATTCACAG AAGAACCCAT TGCTTATGGG GACATCACCG TGGAGATGGT CTCTGAGGAA 
GAGGAGGAGG ACTGGGCCAG TAGACACTTC CGGATCAACT ATGCGGACGA AGCGCAGGAC 
GTGATGCATT TTAACTACAC AGCCTGGCCC GATCACGGCG TGCCTCCAGC AAACGCCGCC 
GAGAGCATCC TGCAGTTTGT GTTCACAGTG CGACAGCAAG CCGCCAAGAG CAAAGGGCCC 
ATGATCATCC ACTGCAGTGC GGGTGTGGGA CGGACAGGAA CCTTCATTGC CCTGGACAGG 
CTCCTGCAAC ACATTCGAGA TCATGAATTT GTGGACATCT TAGGGCTGGT ATCAGAGATG 
CGCTCATACC GAATGTCAAT GGTACAGACA GAGGAGCAGT ACATTTTTAT CCATCAGTGT 
GTGCAGCTGA TGTGGCTGAG GAAGAAGCAA CAGTTCTGCA TCAGCGACGT CATCTACGAG 
AACGTCAGCA AATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001157874.1
CDS	397..1614
Translation	MVTEVNPNVVVISVLAILSTLLIGLLLVTLVILRKKHLQMARECGAGTFVNFASLEREGKLPYSWRRSVFALLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSHIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMVSEEEEEDWASRHFRINYADEAQDVMHFNYTAWPDHGVPPANAAESILQFVFTVRQQAAKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLRKKQQFCISDVIYENVSKS

Target ORF information:

RefSeq Version	NM_001164402.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001164402.1

ORF Insert Sequence:

ATGGTTACAG AGGTGAACCC TAACGTGGTG GTGATCTCGG TGCTGGCCAT CCTCAGCACA 
CTTTTAATTG GACTGCTCTT AGTGACCCTT GTCATTCTCC GAAAGAAGCA CCTGCAGATG 
GCTAGGGAAT GTGGAGCTGG CACGTTTGTT AACTTTGCAT CCTTAGAAAG GGAAGGGAAA 
CTCCCCTACA GTTGGCGTAG GAGTGTGTTT GCTCTCTTAA CCCTGCTGCC TTCATGTCTT 
TGGACTGACT ATCTTTTGGC ATTTTATATT AACCCTTGGA GTAAAAATGG CTTAAAGAAG 
AGGAAACTAA CAAACCCCGT TCAGCTGGAT GACTTCGATT CTTACATCAA GGATATGGCC 
AAGGACTCGG ACTATAAATT CTCTCTTCAG TTTGAGGAGT TGAAGTTGAT TGGACTGGAT 
ATTCCGCACT TTGCTGCAGA TCTACCGCTG AACCGATGTA AAAACCGCTA CACAAACATC 
CTGCCGTATG ACTTTAGCCG GGTGAGGCTA GTCTCCATGA ACGAAGAGGA AGGAGCAGAC 
TACATTAATG CCAACTATAT TCCTGGATAC AACTCACCCC AGGAGTACAT TGCCACCCAG 
GGTCCCCTGC CAGAAACCAG AAATGACTTC TGGAAGATGG TCCTACAACA GAAGTCCCAC 
ATCATCGTCA TGCTCACTCA ATGCAATGAG AAAAGGAGGG TAAAATGTGA CCACTACTGG 
CCATTCACAG AAGAACCCAT TGCTTATGGG GACATCACCG TGGAGATGGT CTCTGAGGAA 
GAGGAGGAGG ACTGGGCCAG TAGACACTTC CGGATCAACT ATGCGGACGA AGCGCAGGAC 
GTGATGCATT TTAACTACAC AGCCTGGCCC GATCACGGCG TGCCTCCAGC AAACGCCGCC 
GAGAGCATCC TGCAGTTTGT GTTCACAGTG CGACAGCAAG CCGCCAAGAG CAAAGGGCCC 
ATGATCATCC ACTGCAGTGC GGGTGTGGGA CGGACAGGAA CCTTCATTGC CCTGGACAGG 
CTCCTGCAAC ACATTCGAGA TCATGAATTT GTGGACATCT TAGGGCTGGT ATCAGAGATG 
CGCTCATACC GAATGTCAAT GGTACAGACA GAGGAGCAGT ACATTTTTAT CCATCAGTGT 
GTGCAGCTGA TGTGGCTGAG GAAGAAGCAA CAGTTCTGCA TCAGCGACGT CATCTACGAG 
AACGTCAGCA AATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ptpro ( NM_001164403.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001157875.1 Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu09786
Clone ID Related Accession (Same CDS sequence)	NM_001164403.1
Accession Version	NM_001164403.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	receptor-type tyrosine-protein phosphatase O isoform 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC163627.4, AC093120.4 and AW490226.1. Transcript Variant: This variant (4) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences causes translation initiation at a downstream AUG, compared to variant 1. The encoded isoform (4) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U37466.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTTACAG AGGTGAACCC TAACGTGGTG GTGATCTCGG TGCTGGCCAT CCTCAGCACA 
CTTTTAATTG GACTGCTCTT AGTGACCCTT GTCATTCTCC GAAAGAAGCA CCTGCAGATG 
GCTAGGGAAT GTGGAGCTGG CACGTTTGTT AACTTTGCAT CCTTAGAAAG GGAAGGGAAA 
CTCCCCTACA GTTGGAGTAA AAATGGCTTA AAGAAGAGGA AACTAACAAA CCCCGTTCAG 
CTGGATGACT TCGATTCTTA CATCAAGGAT ATGGCCAAGG ACTCGGACTA TAAATTCTCT 
CTTCAGTTTG AGGAGTTGAA GTTGATTGGA CTGGATATTC CGCACTTTGC TGCAGATCTA 
CCGCTGAACC GATGTAAAAA CCGCTACACA AACATCCTGC CGTATGACTT TAGCCGGGTG 
AGGCTAGTCT CCATGAACGA AGAGGAAGGA GCAGACTACA TTAATGCCAA CTATATTCCT 
GGATACAACT CACCCCAGGA GTACATTGCC ACCCAGGGTC CCCTGCCAGA AACCAGAAAT 
GACTTCTGGA AGATGGTCCT ACAACAGAAG TCCCACATCA TCGTCATGCT CACTCAATGC 
AATGAGAAAA GGAGGGTAAA ATGTGACCAC TACTGGCCAT TCACAGAAGA ACCCATTGCT 
TATGGGGACA TCACCGTGGA GATGGTCTCT GAGGAAGAGG AGGAGGACTG GGCCAGTAGA 
CACTTCCGGA TCAACTATGC GGACGAAGCG CAGGACGTGA TGCATTTTAA CTACACAGCC 
TGGCCCGATC ACGGCGTGCC TCCAGCAAAC GCCGCCGAGA GCATCCTGCA GTTTGTGTTC 
ACAGTGCGAC AGCAAGCCGC CAAGAGCAAA GGGCCCATGA TCATCCACTG CAGTGCGGGT 
GTGGGACGGA CAGGAACCTT CATTGCCCTG GACAGGCTCC TGCAACACAT TCGAGATCAT 
GAATTTGTGG ACATCTTAGG GCTGGTATCA GAGATGCGCT CATACCGAAT GTCAATGGTA 
CAGACAGAGG AGCAGTACAT TTTTATCCAT CAGTGTGTGC AGCTGATGTG GCTGAGGAAG 
AAGCAACAGT TCTGCATCAG CGACGTCATC TACGAGAACG TCAGCAAATC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001157875.1
CDS	397..1530
Translation	MVTEVNPNVVVISVLAILSTLLIGLLLVTLVILRKKHLQMARECGAGTFVNFASLEREGKLPYSWSKNGLKKRKLTNPVQLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSHIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMVSEEEEEDWASRHFRINYADEAQDVMHFNYTAWPDHGVPPANAAESILQFVFTVRQQAAKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLRKKQQFCISDVIYENVSKS

Target ORF information:

RefSeq Version	NM_001164403.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001164403.1

ORF Insert Sequence:

ATGGTTACAG AGGTGAACCC TAACGTGGTG GTGATCTCGG TGCTGGCCAT CCTCAGCACA 
CTTTTAATTG GACTGCTCTT AGTGACCCTT GTCATTCTCC GAAAGAAGCA CCTGCAGATG 
GCTAGGGAAT GTGGAGCTGG CACGTTTGTT AACTTTGCAT CCTTAGAAAG GGAAGGGAAA 
CTCCCCTACA GTTGGAGTAA AAATGGCTTA AAGAAGAGGA AACTAACAAA CCCCGTTCAG 
CTGGATGACT TCGATTCTTA CATCAAGGAT ATGGCCAAGG ACTCGGACTA TAAATTCTCT 
CTTCAGTTTG AGGAGTTGAA GTTGATTGGA CTGGATATTC CGCACTTTGC TGCAGATCTA 
CCGCTGAACC GATGTAAAAA CCGCTACACA AACATCCTGC CGTATGACTT TAGCCGGGTG 
AGGCTAGTCT CCATGAACGA AGAGGAAGGA GCAGACTACA TTAATGCCAA CTATATTCCT 
GGATACAACT CACCCCAGGA GTACATTGCC ACCCAGGGTC CCCTGCCAGA AACCAGAAAT 
GACTTCTGGA AGATGGTCCT ACAACAGAAG TCCCACATCA TCGTCATGCT CACTCAATGC 
AATGAGAAAA GGAGGGTAAA ATGTGACCAC TACTGGCCAT TCACAGAAGA ACCCATTGCT 
TATGGGGACA TCACCGTGGA GATGGTCTCT GAGGAAGAGG AGGAGGACTG GGCCAGTAGA 
CACTTCCGGA TCAACTATGC GGACGAAGCG CAGGACGTGA TGCATTTTAA CTACACAGCC 
TGGCCCGATC ACGGCGTGCC TCCAGCAAAC GCCGCCGAGA GCATCCTGCA GTTTGTGTTC 
ACAGTGCGAC AGCAAGCCGC CAAGAGCAAA GGGCCCATGA TCATCCACTG CAGTGCGGGT 
GTGGGACGGA CAGGAACCTT CATTGCCCTG GACAGGCTCC TGCAACACAT TCGAGATCAT 
GAATTTGTGG ACATCTTAGG GCTGGTATCA GAGATGCGCT CATACCGAAT GTCAATGGTA 
CAGACAGAGG AGCAGTACAT TTTTATCCAT CAGTGTGTGC AGCTGATGTG GCTGAGGAAG 
AAGCAACAGT TCTGCATCAG CGACGTCATC TACGAGAACG TCAGCAAATC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ptpro ( XM_030255238.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030111098.1 Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu89155
Clone ID Related Accession (Same CDS sequence)	XM_030255238.1
Accession Version	XM_030255238.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3186bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	receptor-type tyrosine-protein phosphatase O isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTACA AAGATTTCTT TAAGGGGAAA ACGGTGTTTA ATCACTGGCT ACCAGGACTA 
TGTTACAGTA ACATCACTTT CCAGCTGGTA TCGGAGGCAA CTTTTAATAA AAGTACCCTT 
GTGGAGTACA GTGGTGTGAG CCATGAACCC AAACAGCACA GAACAGCACC ATATCCACCT 
CGAAACATCT CTGTTCGCTT TGTCAACTTG AACAAGAACA ACTGGGAGGA GCCGAGCGGG 
AGCTTCCCCG AGGACTCGTT CATCAAACCA CCGCAAGATT CAATAGGAAG AGACAGACGC 
TTCCATTTCC CCGAAGAAAC TCCGGAGACT CCCCCCAGCA ATGTGTCCTC CGGTTCTCCC 
CCCAGCAATG TGTCCTCCGC TTGGCCTGAC CCGAATAGCA CAGACTATGA AAGCACATCA 
CAGCCCTTCT GGTGGGACAG TGCATCCGCG GCCCCTGAAA ACGAGGAGGA CTTTGTCAGT 
GCGCTGCCAG CAGACTATGA CACTGAGACC ACACTCGATA GGACAGAGAA GCCCACAGCC 
GACCCTTTCT CTGCCTTCCC TGTGCAGATG ACTCTGAGCT GGTTACCACC CAAACCGCCC 
ACAGCCTTTG ATGGCTTCAA TATCCTCATA GAGAGGGAAG AGAACTTTAC TGACTATTTG 
ACAGTGGATG AAGAAGCCCA TGAATTCGTT GCAGAACTGA AGGAGCCTGG GAAATACAAA 
CTCTCAGTGA CAACCTTTAG CTCCTCGGGG GCCTGTGAGA CTCGGAAAAG CCAGTCAGCA 
AAATCGCTCA GCTTCTACAT CAGCCCCACA GGCGAGTGGA TTGAAGAACT GACCGAGAAA 
CCTCAGCATG TGAGTGTCCA CGTCTTAAGC TCAACCACCG CCTTGATGTC GTGGACATCT 
TCTCAGGAGA ACTACAACAG CACCATTGTG TCTGTGGTGT CCTTGACCTG CCAGAAACAG 
AAGGAGAGCC AGCGGCTGGA GAAGCAGTAT TGTACCCAGG TGAACTCAAG CAAACCTGTA 
ATTGAGAACC TGGTTCCTGG TGCCCAGTAC CAGGTTGTGA TGTACTTAAG AAAAGGCCCT 
TTGATTGGGC CACCTTCCGA TCCTGTGACA TTTGCGATTG TTCCCACTGG GATCAAAGAT 
TTAATGCTCT ACCCCTTGGG TCCCACTGCT GTCGTGCTGA GCTGGACCCG ACCTATCCTG 
GGAGTCTTCA GAAAATACGT GGTTGAAATG TTCTACTTCA ACCCCACCAC CATGACCTCA 
GAGTGGACGA CCTACTATGA GATAGCAGCC ACAGTTTCCT TAACGGCATC CGTGAGAATA 
GCAAGCCTAT TGCCAGCGTG GTACTACAAC TTCCGCGTAA CCATGGTGAC ATGGGGAGAT 
CCAGAGCTGA GCTGTTGTGA CAGTTCCACC ATCAGCTTCA TAACAGCCCC CGTTGCTCCA 
GAAATCACGT CTGTGGAGTA CTTCAACAGC CTGCTGTACA TCAGTTGGAC CTATGGGGAT 
GCCACCACTG ACCTGTCCCA CTCTAGAATG CTGCACTGGA TGGTCGTTGC AGAAGGGAGG 
AAGAAAATTA AAAAGAGTGT GACACGCAAT GTCATGACGG CCATCCTTAG CCTGCCTCCA 
GGAGATATCT ACAATCTGTC TGTCACGGCC TGCACTGAGA GAGGGAGCAA CACCTCCTTG 
CCCCGCCTTG TCAAGCTCGA ACCAGCCCCT CCGAAGTCAC TCTTCGCAGT GAACAAAACA 
CAGACGTCAG TGACCCTGCT GTGGGTTGAG GAGGGTGTTG CTGATTTCTT TGAAGTCTTC 
TGTCAGCAGC TCGGCTCTGG CCACAATGGC AAACTCCAGG AGCCAGTAGC TGTGTCGTCC 
CACGTGGTGA CCATCTCCAG CCTCCTCCCA GCCACTGCCT ACAACTGCAG TGTCACCAGC 
TTCAGCCACG ACACTCCCAG TGTCCCTACA TTCATAGCTG TCTCCACAAT GGTTACAGAG 
GTGAACCCTA ACGTGGTGGT GATCTCGGTG CTGGCCATCC TCAGCACACT TTTAATTGGA 
CTGCTCTTAG TGACCCTTGT CATTCTCCGA AAGAAGCACC TGCAGATGGC TAGGGAATGT 
GGAGCTGGCA CGTTTGTTAA CTTTGCATCC TTAGAAAGGG AAGGGAAACT CCCCTACAGT 
TGGCGTAGGA GTGTGTTTGC TCTCTTAACC CTGCTGCCTT CATGTCTTTG GACTGACTAT 
CTTTTGGCAT TTTATATTAA CCCTTGGAGT AAAAATGGCT TAAAGAAGAG GAAACTAACA 
AACCCCGTTC AGCTGGATGA CTTCGATTCT TACATCAAGG ATATGGCCAA GGACTCGGAC 
TATAAATTCT CTCTTCAGTT TGAGGAGTTG AAGTTGATTG GACTGGATAT TCCGCACTTT 
GCTGCAGATC TACCGCTGAA CCGATGTAAA AACCGCTACA CAAACATCCT GCCGTATGAC 
TTTAGCCGGG TGAGGCTAGT CTCCATGAAC GAAGAGGAAG GAGCAGACTA CATTAATGCC 
AACTATATTC CTGGATACAA CTCACCCCAG GAGTACATTG CCACCCAGGG TCCCCTGCCA 
GAAACCAGAA ATGACTTCTG GAAGATGGTC CTACAACAGA AGTCCCACAT CATCGTCATG 
CTCACTCAAT GCAATGAGAA AAGGAGGGTA AAATGTGACC ACTACTGGCC ATTCACAGAA 
GAACCCATTG CTTATGGGGA CATCACCGTG GAGATGGTCT CTGAGGAAGA GGAGGAGGAC 
TGGGCCAGTA GACACTTCCG GATCAACTAT GCGGACGAAG CGCAGGACGT GATGCATTTT 
AACTACACAG CCTGGCCCGA TCACGGCGTG CCTCCAGCAA ACGCCGCCGA GAGCATCCTG 
CAGTTTGTGT TCACAGTGCG ACAGCAAGCC GCCAAGAGCA AAGGGCCCAT GATCATCCAC 
TGCAGTGCGG GTGTGGGACG GACAGGAACC TTCATTGCCC TGGACAGGCT CCTGCAACAC 
ATTCGAGATC ATGAATTTGT GGACATCTTA GGGCTGGTAT CAGAGATGCG CTCATACCGA 
ATGTCAATGG TACAGACAGA GGAGCAGTAC ATTTTTATCC ATCAGTGTGT GCAGCTGATG 
TGGCTGAGGA AGAAGCAACA GTTCTGCATC AGCGACGTCA TCTACGAGAA CGTCAGCAAA 
TCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030111098.1
CDS	672..3857
Translation	MLYKDFFKGKTVFNHWLPGLCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRFVNLNKNNWEEPSGSFPEDSFIKPPQDSIGRDRRFHFPEETPETPPSNVSSGSPPSNVSSAWPDPNSTDYESTSQPFWWDSASAAPENEEDFVSALPADYDTETTLDRTEKPTADPFSAFPVQMTLSWLPPKPPTAFDGFNILIEREENFTDYLTVDEEAHEFVAELKEPGKYKLSVTTFSSSGACETRKSQSAKSLSFYISPTGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPILGVFRKYVVEMFYFNPTTMTSEWTTYYEIAATVSLTASVRIASLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDATTDLSHSRMLHWMVVAEGRKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSLPRLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQLGSGHNGKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHDTPSVPTFIAVSTMVTEVNPNVVVISVLAILSTLLIGLLLVTLVILRKKHLQMARECGAGTFVNFASLEREGKLPYSWRRSVFALLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSHIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMVSEEEEEDWASRHFRINYADEAQDVMHFNYTAWPDHGVPPANAAESILQFVFTVRQQAAKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLRKKQQFCISDVIYENVSKS

Target ORF information:

RefSeq Version	XM_030255238.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030255238.1

ORF Insert Sequence:

ATGCTGTACA AAGATTTCTT TAAGGGGAAA ACGGTGTTTA ATCACTGGCT ACCAGGACTA 
TGTTACAGTA ACATCACTTT CCAGCTGGTA TCGGAGGCAA CTTTTAATAA AAGTACCCTT 
GTGGAGTACA GTGGTGTGAG CCATGAACCC AAACAGCACA GAACAGCACC ATATCCACCT 
CGAAACATCT CTGTTCGCTT TGTCAACTTG AACAAGAACA ACTGGGAGGA GCCGAGCGGG 
AGCTTCCCCG AGGACTCGTT CATCAAACCA CCGCAAGATT CAATAGGAAG AGACAGACGC 
TTCCATTTCC CCGAAGAAAC TCCGGAGACT CCCCCCAGCA ATGTGTCCTC CGGTTCTCCC 
CCCAGCAATG TGTCCTCCGC TTGGCCTGAC CCGAATAGCA CAGACTATGA AAGCACATCA 
CAGCCCTTCT GGTGGGACAG TGCATCCGCG GCCCCTGAAA ACGAGGAGGA CTTTGTCAGT 
GCGCTGCCAG CAGACTATGA CACTGAGACC ACACTCGATA GGACAGAGAA GCCCACAGCC 
GACCCTTTCT CTGCCTTCCC TGTGCAGATG ACTCTGAGCT GGTTACCACC CAAACCGCCC 
ACAGCCTTTG ATGGCTTCAA TATCCTCATA GAGAGGGAAG AGAACTTTAC TGACTATTTG 
ACAGTGGATG AAGAAGCCCA TGAATTCGTT GCAGAACTGA AGGAGCCTGG GAAATACAAA 
CTCTCAGTGA CAACCTTTAG CTCCTCGGGG GCCTGTGAGA CTCGGAAAAG CCAGTCAGCA 
AAATCGCTCA GCTTCTACAT CAGCCCCACA GGCGAGTGGA TTGAAGAACT GACCGAGAAA 
CCTCAGCATG TGAGTGTCCA CGTCTTAAGC TCAACCACCG CCTTGATGTC GTGGACATCT 
TCTCAGGAGA ACTACAACAG CACCATTGTG TCTGTGGTGT CCTTGACCTG CCAGAAACAG 
AAGGAGAGCC AGCGGCTGGA GAAGCAGTAT TGTACCCAGG TGAACTCAAG CAAACCTGTA 
ATTGAGAACC TGGTTCCTGG TGCCCAGTAC CAGGTTGTGA TGTACTTAAG AAAAGGCCCT 
TTGATTGGGC CACCTTCCGA TCCTGTGACA TTTGCGATTG TTCCCACTGG GATCAAAGAT 
TTAATGCTCT ACCCCTTGGG TCCCACTGCT GTCGTGCTGA GCTGGACCCG ACCTATCCTG 
GGAGTCTTCA GAAAATACGT GGTTGAAATG TTCTACTTCA ACCCCACCAC CATGACCTCA 
GAGTGGACGA CCTACTATGA GATAGCAGCC ACAGTTTCCT TAACGGCATC CGTGAGAATA 
GCAAGCCTAT TGCCAGCGTG GTACTACAAC TTCCGCGTAA CCATGGTGAC ATGGGGAGAT 
CCAGAGCTGA GCTGTTGTGA CAGTTCCACC ATCAGCTTCA TAACAGCCCC CGTTGCTCCA 
GAAATCACGT CTGTGGAGTA CTTCAACAGC CTGCTGTACA TCAGTTGGAC CTATGGGGAT 
GCCACCACTG ACCTGTCCCA CTCTAGAATG CTGCACTGGA TGGTCGTTGC AGAAGGGAGG 
AAGAAAATTA AAAAGAGTGT GACACGCAAT GTCATGACGG CCATCCTTAG CCTGCCTCCA 
GGAGATATCT ACAATCTGTC TGTCACGGCC TGCACTGAGA GAGGGAGCAA CACCTCCTTG 
CCCCGCCTTG TCAAGCTCGA ACCAGCCCCT CCGAAGTCAC TCTTCGCAGT GAACAAAACA 
CAGACGTCAG TGACCCTGCT GTGGGTTGAG GAGGGTGTTG CTGATTTCTT TGAAGTCTTC 
TGTCAGCAGC TCGGCTCTGG CCACAATGGC AAACTCCAGG AGCCAGTAGC TGTGTCGTCC 
CACGTGGTGA CCATCTCCAG CCTCCTCCCA GCCACTGCCT ACAACTGCAG TGTCACCAGC 
TTCAGCCACG ACACTCCCAG TGTCCCTACA TTCATAGCTG TCTCCACAAT GGTTACAGAG 
GTGAACCCTA ACGTGGTGGT GATCTCGGTG CTGGCCATCC TCAGCACACT TTTAATTGGA 
CTGCTCTTAG TGACCCTTGT CATTCTCCGA AAGAAGCACC TGCAGATGGC TAGGGAATGT 
GGAGCTGGCA CGTTTGTTAA CTTTGCATCC TTAGAAAGGG AAGGGAAACT CCCCTACAGT 
TGGCGTAGGA GTGTGTTTGC TCTCTTAACC CTGCTGCCTT CATGTCTTTG GACTGACTAT 
CTTTTGGCAT TTTATATTAA CCCTTGGAGT AAAAATGGCT TAAAGAAGAG GAAACTAACA 
AACCCCGTTC AGCTGGATGA CTTCGATTCT TACATCAAGG ATATGGCCAA GGACTCGGAC 
TATAAATTCT CTCTTCAGTT TGAGGAGTTG AAGTTGATTG GACTGGATAT TCCGCACTTT 
GCTGCAGATC TACCGCTGAA CCGATGTAAA AACCGCTACA CAAACATCCT GCCGTATGAC 
TTTAGCCGGG TGAGGCTAGT CTCCATGAAC GAAGAGGAAG GAGCAGACTA CATTAATGCC 
AACTATATTC CTGGATACAA CTCACCCCAG GAGTACATTG CCACCCAGGG TCCCCTGCCA 
GAAACCAGAA ATGACTTCTG GAAGATGGTC CTACAACAGA AGTCCCACAT CATCGTCATG 
CTCACTCAAT GCAATGAGAA AAGGAGGGTA AAATGTGACC ACTACTGGCC ATTCACAGAA 
GAACCCATTG CTTATGGGGA CATCACCGTG GAGATGGTCT CTGAGGAAGA GGAGGAGGAC 
TGGGCCAGTA GACACTTCCG GATCAACTAT GCGGACGAAG CGCAGGACGT GATGCATTTT 
AACTACACAG CCTGGCCCGA TCACGGCGTG CCTCCAGCAA ACGCCGCCGA GAGCATCCTG 
CAGTTTGTGT TCACAGTGCG ACAGCAAGCC GCCAAGAGCA AAGGGCCCAT GATCATCCAC 
TGCAGTGCGG GTGTGGGACG GACAGGAACC TTCATTGCCC TGGACAGGCT CCTGCAACAC 
ATTCGAGATC ATGAATTTGT GGACATCTTA GGGCTGGTAT CAGAGATGCG CTCATACCGA 
ATGTCAATGG TACAGACAGA GGAGCAGTAC ATTTTTATCC ATCAGTGTGT GCAGCTGATG 
TGGCTGAGGA AGAAGCAACA GTTCTGCATC AGCGACGTCA TCTACGAGAA CGTCAGCAAA 
TCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ptpro ( NM_011216.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035346.3 Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu07707
Clone ID Related Accession (Same CDS sequence)	NM_011216.3
Accession Version	NM_011216.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3681bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	receptor-type tyrosine-protein phosphatase O isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB523320.1, BC052743.1, AC163627.4, AC093120.4 and AW490226.1. On Sep 2, 2009 this sequence version replaced NM_011216.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660813.255740.1, BC052743.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849385, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCACC TGCCTAGGGG AACGCTCGGG GGCCGCCGCC TGCTACCTCT GCTCGGGCTC 
TTTGTGCTGC TCAAGATTGT TACGACGTTC CACGTGGCTG TGCAAGATGA CAACAATATC 
GTTGTGTCTT TAGAAGCTTC TGATATAGTC AGCCCAGCAT CTGTGTATGT TGTGAGGGTA 
GCTGGCGAAT CAAAAAACTA TTTCTTCGAA TTTGAGGAAT TTAACAGCAC ATTGCCTCCT 
CCTGTGGTCT TTAAGGCCAC ATATCACGGT CTTTATTACA TAATCACTCT GGTGGTAGTC 
AACGGGAATG TGGTCACCAA ACCATCCAGA TCAATCACCG TGTTGACAAA ACCCTTGCCT 
GTAACCAGTG TGTCTATCTA TGACTATAAA CCTTCTCCTG AGACAGGAGT CCTGTTTGAA 
ATCCATTATC CGGAAAAATA CAATGTGTTC AGCAGAGTGA ACATCAGCTA CTGGGAAGGG 
AGGGACTTCA GGACGATGCT GTACAAAGAT TTCTTTAAGG GGAAAACGGT GTTTAATCAC 
TGGCTACCAG GACTATGTTA CAGTAACATC ACTTTCCAGC TGGTATCGGA GGCAACTTTT 
AATAAAAGTA CCCTTGTGGA GTACAGTGGT GTGAGCCATG AACCCAAACA GCACAGAACA 
GCACCATATC CACCTCGAAA CATCTCTGTT CGCTTTGTCA ACTTGAACAA GAACAACTGG 
GAGGAGCCGA GCGGGAGCTT CCCCGAGGAC TCGTTCATCA AACCACCGCA AGATTCAATA 
GGAAGAGACA GACGCTTCCA TTTCCCCGAA GAAACTCCGG AGACTCCCCC CAGCAATGTG 
TCCTCCGGTT CTCCCCCCAG CAATGTGTCC TCCGCTTGGC CTGACCCGAA TAGCACAGAC 
TATGAAAGCA CATCACAGCC CTTCTGGTGG GACAGTGCAT CCGCGGCCCC TGAAAACGAG 
GAGGACTTTG TCAGTGCGCT GCCAGCAGAC TATGACACTG AGACCACACT CGATAGGACA 
GAGAAGCCCA CAGCCGACCC TTTCTCTGCC TTCCCTGTGC AGATGACTCT GAGCTGGTTA 
CCACCCAAAC CGCCCACAGC CTTTGATGGC TTCAATATCC TCATAGAGAG GGAAGAGAAC 
TTTACTGACT ATTTGACAGT GGATGAAGAA GCCCATGAAT TCGTTGCAGA ACTGAAGGAG 
CCTGGGAAAT ACAAACTCTC AGTGACAACC TTTAGCTCCT CGGGGGCCTG TGAGACTCGG 
AAAAGCCAGT CAGCAAAATC GCTCAGCTTC TACATCAGCC CCACAGGCGA GTGGATTGAA 
GAACTGACCG AGAAACCTCA GCATGTGAGT GTCCACGTCT TAAGCTCAAC CACCGCCTTG 
ATGTCGTGGA CATCTTCTCA GGAGAACTAC AACAGCACCA TTGTGTCTGT GGTGTCCTTG 
ACCTGCCAGA AACAGAAGGA GAGCCAGCGG CTGGAGAAGC AGTATTGTAC CCAGGTGAAC 
TCAAGCAAAC CTGTAATTGA GAACCTGGTT CCTGGTGCCC AGTACCAGGT TGTGATGTAC 
TTAAGAAAAG GCCCTTTGAT TGGGCCACCT TCCGATCCTG TGACATTTGC GATTGTTCCC 
ACTGGGATCA AAGATTTAAT GCTCTACCCC TTGGGTCCCA CTGCTGTCGT GCTGAGCTGG 
ACCCGACCTA TCCTGGGAGT CTTCAGAAAA TACGTGGTTG AAATGTTCTA CTTCAACCCC 
ACCACCATGA CCTCAGAGTG GACGACCTAC TATGAGATAG CAGCCACAGT TTCCTTAACG 
GCATCCGTGA GAATAGCAAG CCTATTGCCA GCGTGGTACT ACAACTTCCG CGTAACCATG 
GTGACATGGG GAGATCCAGA GCTGAGCTGT TGTGACAGTT CCACCATCAG CTTCATAACA 
GCCCCCGTTG CTCCAGAAAT CACGTCTGTG GAGTACTTCA ACAGCCTGCT GTACATCAGT 
TGGACCTATG GGGATGCCAC CACTGACCTG TCCCACTCTA GAATGCTGCA CTGGATGGTC 
GTTGCAGAAG GGAGGAAGAA AATTAAAAAG AGTGTGACAC GCAATGTCAT GACGGCCATC 
CTTAGCCTGC CTCCAGGAGA TATCTACAAT CTGTCTGTCA CGGCCTGCAC TGAGAGAGGG 
AGCAACACCT CCTTGCCCCG CCTTGTCAAG CTCGAACCAG CCCCTCCGAA GTCACTCTTC 
GCAGTGAACA AAACACAGAC GTCAGTGACC CTGCTGTGGG TTGAGGAGGG TGTTGCTGAT 
TTCTTTGAAG TCTTCTGTCA GCAGCTCGGC TCTGGCCACA ATGGCAAACT CCAGGAGCCA 
GTAGCTGTGT CGTCCCACGT GGTGACCATC TCCAGCCTCC TCCCAGCCAC TGCCTACAAC 
TGCAGTGTCA CCAGCTTCAG CCACGACACT CCCAGTGTCC CTACATTCAT AGCTGTCTCC 
ACAATGGTTA CAGAGGTGAA CCCTAACGTG GTGGTGATCT CGGTGCTGGC CATCCTCAGC 
ACACTTTTAA TTGGACTGCT CTTAGTGACC CTTGTCATTC TCCGAAAGAA GCACCTGCAG 
ATGGCTAGGG AATGTGGAGC TGGCACGTTT GTTAACTTTG CATCCTTAGA AAGGGAAGGG 
AAACTCCCCT ACAGTTGGCG TAGGAGTGTG TTTGCTCTCT TAACCCTGCT GCCTTCATGT 
CTTTGGACTG ACTATCTTTT GGCATTTTAT ATTAACCCTT GGAGTAAAAA TGGCTTAAAG 
AAGAGGAAAC TAACAAACCC CGTTCAGCTG GATGACTTCG ATTCTTACAT CAAGGATATG 
GCCAAGGACT CGGACTATAA ATTCTCTCTT CAGTTTGAGG AGTTGAAGTT GATTGGACTG 
GATATTCCGC ACTTTGCTGC AGATCTACCG CTGAACCGAT GTAAAAACCG CTACACAAAC 
ATCCTGCCGT ATGACTTTAG CCGGGTGAGG CTAGTCTCCA TGAACGAAGA GGAAGGAGCA 
GACTACATTA ATGCCAACTA TATTCCTGGA TACAACTCAC CCCAGGAGTA CATTGCCACC 
CAGGGTCCCC TGCCAGAAAC CAGAAATGAC TTCTGGAAGA TGGTCCTACA ACAGAAGTCC 
CACATCATCG TCATGCTCAC TCAATGCAAT GAGAAAAGGA GGGTAAAATG TGACCACTAC 
TGGCCATTCA CAGAAGAACC CATTGCTTAT GGGGACATCA CCGTGGAGAT GGTCTCTGAG 
GAAGAGGAGG AGGACTGGGC CAGTAGACAC TTCCGGATCA ACTATGCGGA CGAAGCGCAG 
GACGTGATGC ATTTTAACTA CACAGCCTGG CCCGATCACG GCGTGCCTCC AGCAAACGCC 
GCCGAGAGCA TCCTGCAGTT TGTGTTCACA GTGCGACAGC AAGCCGCCAA GAGCAAAGGG 
CCCATGATCA TCCACTGCAG TGCGGGTGTG GGACGGACAG GAACCTTCAT TGCCCTGGAC 
AGGCTCCTGC AACACATTCG AGATCATGAA TTTGTGGACA TCTTAGGGCT GGTATCAGAG 
ATGCGCTCAT ACCGAATGTC AATGGTACAG ACAGAGGAGC AGTACATTTT TATCCATCAG 
TGTGTGCAGC TGATGTGGCT GAGGAAGAAG CAACAGTTCT GCATCAGCGA CGTCATCTAC 
GAGAACGTCA GCAAATCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035346.3
CDS	388..4068
Translation	MGHLPRGTLGGRRLLPLLGLFVLLKIVTTFHVAVQDDNNIVVSLEASDIVSPASVYVVRVAGESKNYFFEFEEFNSTLPPPVVFKATYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLPVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFNHWLPGLCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRFVNLNKNNWEEPSGSFPEDSFIKPPQDSIGRDRRFHFPEETPETPPSNVSSGSPPSNVSSAWPDPNSTDYESTSQPFWWDSASAAPENEEDFVSALPADYDTETTLDRTEKPTADPFSAFPVQMTLSWLPPKPPTAFDGFNILIEREENFTDYLTVDEEAHEFVAELKEPGKYKLSVTTFSSSGACETRKSQSAKSLSFYISPTGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPILGVFRKYVVEMFYFNPTTMTSEWTTYYEIAATVSLTASVRIASLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDATTDLSHSRMLHWMVVAEGRKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSLPRLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQLGSGHNGKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHDTPSVPTFIAVSTMVTEVNPNVVVISVLAILSTLLIGLLLVTLVILRKKHLQMARECGAGTFVNFASLEREGKLPYSWRRSVFALLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSHIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMVSEEEEEDWASRHFRINYADEAQDVMHFNYTAWPDHGVPPANAAESILQFVFTVRQQAAKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLRKKQQFCISDVIYENVSKS

Target ORF information:

RefSeq Version	NM_011216.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011216.3

ORF Insert Sequence:

ATGGGGCACC TGCCTAGGGG AACGCTCGGG GGCCGCCGCC TGCTACCTCT GCTCGGGCTC 
TTTGTGCTGC TCAAGATTGT TACGACGTTC CACGTGGCTG TGCAAGATGA CAACAATATC 
GTTGTGTCTT TAGAAGCTTC TGATATAGTC AGCCCAGCAT CTGTGTATGT TGTGAGGGTA 
GCTGGCGAAT CAAAAAACTA TTTCTTCGAA TTTGAGGAAT TTAACAGCAC ATTGCCTCCT 
CCTGTGGTCT TTAAGGCCAC ATATCACGGT CTTTATTACA TAATCACTCT GGTGGTAGTC 
AACGGGAATG TGGTCACCAA ACCATCCAGA TCAATCACCG TGTTGACAAA ACCCTTGCCT 
GTAACCAGTG TGTCTATCTA TGACTATAAA CCTTCTCCTG AGACAGGAGT CCTGTTTGAA 
ATCCATTATC CGGAAAAATA CAATGTGTTC AGCAGAGTGA ACATCAGCTA CTGGGAAGGG 
AGGGACTTCA GGACGATGCT GTACAAAGAT TTCTTTAAGG GGAAAACGGT GTTTAATCAC 
TGGCTACCAG GACTATGTTA CAGTAACATC ACTTTCCAGC TGGTATCGGA GGCAACTTTT 
AATAAAAGTA CCCTTGTGGA GTACAGTGGT GTGAGCCATG AACCCAAACA GCACAGAACA 
GCACCATATC CACCTCGAAA CATCTCTGTT CGCTTTGTCA ACTTGAACAA GAACAACTGG 
GAGGAGCCGA GCGGGAGCTT CCCCGAGGAC TCGTTCATCA AACCACCGCA AGATTCAATA 
GGAAGAGACA GACGCTTCCA TTTCCCCGAA GAAACTCCGG AGACTCCCCC CAGCAATGTG 
TCCTCCGGTT CTCCCCCCAG CAATGTGTCC TCCGCTTGGC CTGACCCGAA TAGCACAGAC 
TATGAAAGCA CATCACAGCC CTTCTGGTGG GACAGTGCAT CCGCGGCCCC TGAAAACGAG 
GAGGACTTTG TCAGTGCGCT GCCAGCAGAC TATGACACTG AGACCACACT CGATAGGACA 
GAGAAGCCCA CAGCCGACCC TTTCTCTGCC TTCCCTGTGC AGATGACTCT GAGCTGGTTA 
CCACCCAAAC CGCCCACAGC CTTTGATGGC TTCAATATCC TCATAGAGAG GGAAGAGAAC 
TTTACTGACT ATTTGACAGT GGATGAAGAA GCCCATGAAT TCGTTGCAGA ACTGAAGGAG 
CCTGGGAAAT ACAAACTCTC AGTGACAACC TTTAGCTCCT CGGGGGCCTG TGAGACTCGG 
AAAAGCCAGT CAGCAAAATC GCTCAGCTTC TACATCAGCC CCACAGGCGA GTGGATTGAA 
GAACTGACCG AGAAACCTCA GCATGTGAGT GTCCACGTCT TAAGCTCAAC CACCGCCTTG 
ATGTCGTGGA CATCTTCTCA GGAGAACTAC AACAGCACCA TTGTGTCTGT GGTGTCCTTG 
ACCTGCCAGA AACAGAAGGA GAGCCAGCGG CTGGAGAAGC AGTATTGTAC CCAGGTGAAC 
TCAAGCAAAC CTGTAATTGA GAACCTGGTT CCTGGTGCCC AGTACCAGGT TGTGATGTAC 
TTAAGAAAAG GCCCTTTGAT TGGGCCACCT TCCGATCCTG TGACATTTGC GATTGTTCCC 
ACTGGGATCA AAGATTTAAT GCTCTACCCC TTGGGTCCCA CTGCTGTCGT GCTGAGCTGG 
ACCCGACCTA TCCTGGGAGT CTTCAGAAAA TACGTGGTTG AAATGTTCTA CTTCAACCCC 
ACCACCATGA CCTCAGAGTG GACGACCTAC TATGAGATAG CAGCCACAGT TTCCTTAACG 
GCATCCGTGA GAATAGCAAG CCTATTGCCA GCGTGGTACT ACAACTTCCG CGTAACCATG 
GTGACATGGG GAGATCCAGA GCTGAGCTGT TGTGACAGTT CCACCATCAG CTTCATAACA 
GCCCCCGTTG CTCCAGAAAT CACGTCTGTG GAGTACTTCA ACAGCCTGCT GTACATCAGT 
TGGACCTATG GGGATGCCAC CACTGACCTG TCCCACTCTA GAATGCTGCA CTGGATGGTC 
GTTGCAGAAG GGAGGAAGAA AATTAAAAAG AGTGTGACAC GCAATGTCAT GACGGCCATC 
CTTAGCCTGC CTCCAGGAGA TATCTACAAT CTGTCTGTCA CGGCCTGCAC TGAGAGAGGG 
AGCAACACCT CCTTGCCCCG CCTTGTCAAG CTCGAACCAG CCCCTCCGAA GTCACTCTTC 
GCAGTGAACA AAACACAGAC GTCAGTGACC CTGCTGTGGG TTGAGGAGGG TGTTGCTGAT 
TTCTTTGAAG TCTTCTGTCA GCAGCTCGGC TCTGGCCACA ATGGCAAACT CCAGGAGCCA 
GTAGCTGTGT CGTCCCACGT GGTGACCATC TCCAGCCTCC TCCCAGCCAC TGCCTACAAC 
TGCAGTGTCA CCAGCTTCAG CCACGACACT CCCAGTGTCC CTACATTCAT AGCTGTCTCC 
ACAATGGTTA CAGAGGTGAA CCCTAACGTG GTGGTGATCT CGGTGCTGGC CATCCTCAGC 
ACACTTTTAA TTGGACTGCT CTTAGTGACC CTTGTCATTC TCCGAAAGAA GCACCTGCAG 
ATGGCTAGGG AATGTGGAGC TGGCACGTTT GTTAACTTTG CATCCTTAGA AAGGGAAGGG 
AAACTCCCCT ACAGTTGGCG TAGGAGTGTG TTTGCTCTCT TAACCCTGCT GCCTTCATGT 
CTTTGGACTG ACTATCTTTT GGCATTTTAT ATTAACCCTT GGAGTAAAAA TGGCTTAAAG 
AAGAGGAAAC TAACAAACCC CGTTCAGCTG GATGACTTCG ATTCTTACAT CAAGGATATG 
GCCAAGGACT CGGACTATAA ATTCTCTCTT CAGTTTGAGG AGTTGAAGTT GATTGGACTG 
GATATTCCGC ACTTTGCTGC AGATCTACCG CTGAACCGAT GTAAAAACCG CTACACAAAC 
ATCCTGCCGT ATGACTTTAG CCGGGTGAGG CTAGTCTCCA TGAACGAAGA GGAAGGAGCA 
GACTACATTA ATGCCAACTA TATTCCTGGA TACAACTCAC CCCAGGAGTA CATTGCCACC 
CAGGGTCCCC TGCCAGAAAC CAGAAATGAC TTCTGGAAGA TGGTCCTACA ACAGAAGTCC 
CACATCATCG TCATGCTCAC TCAATGCAAT GAGAAAAGGA GGGTAAAATG TGACCACTAC 
TGGCCATTCA CAGAAGAACC CATTGCTTAT GGGGACATCA CCGTGGAGAT GGTCTCTGAG 
GAAGAGGAGG AGGACTGGGC CAGTAGACAC TTCCGGATCA ACTATGCGGA CGAAGCGCAG 
GACGTGATGC ATTTTAACTA CACAGCCTGG CCCGATCACG GCGTGCCTCC AGCAAACGCC 
GCCGAGAGCA TCCTGCAGTT TGTGTTCACA GTGCGACAGC AAGCCGCCAA GAGCAAAGGG 
CCCATGATCA TCCACTGCAG TGCGGGTGTG GGACGGACAG GAACCTTCAT TGCCCTGGAC 
AGGCTCCTGC AACACATTCG AGATCATGAA TTTGTGGACA TCTTAGGGCT GGTATCAGAG 
ATGCGCTCAT ACCGAATGTC AATGGTACAG ACAGAGGAGC AGTACATTTT TATCCATCAG 
TGTGTGCAGC TGATGTGGCT GAGGAAGAAG CAACAGTTCT GCATCAGCGA CGTCATCTAC 
GAGAACGTCA GCAAATCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ptpro ( NM_001164401.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001157873.1 Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu09782
Clone ID Related Accession (Same CDS sequence)	NM_001164401.1
Accession Version	NM_001164401.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	receptor-type tyrosine-protein phosphatase O isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC144767.4, AC163627.4, AC093120.4 and AW490226.1. Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF135166.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849385, SAMN01164131 [ECO:0000348] ##Evidence-Data-END##

ATGGGGCACC TGCCTAGGGG AACGCTCGGG GGCCGCCGCC TGCTACCTCT GCTCGGGCTC 
TTTGTGCTGC TCAAGATTGT TACGACGTTC CACGTGGCTG TGCAAGATGA CAACAATATC 
GTTGTGTCTT TAGAAGCTTC TGATATAGTC AGCCCAGCAT CTGTGTATGT TGTGAGGGTA 
GCTGGCGAAT CAAAAAACTA TTTCTTCGAA TTTGAGGAAT TTAACAGCAC ATTGCCTCCT 
CCTGTGGTCT TTAAGGCCAC ATATCACGGT CTTTATTACA TAATCACTCT GGTGGTAGTC 
AACGGGAATG TGGTCACCAA ACCATCCAGA TCAATCACCG TGTTGACAAA ACCCTTGCCT 
GTAACCAGTG TGTCTATCTA TGACTATAAA CCTTCTCCTG AGACAGGAGT CCTGTTTGAA 
ATCCATTATC CGGAAAAATA CAATGTGTTC AGCAGAGTGA ACATCAGCTA CTGGGAAGGG 
AGGGACTTCA GGACGATGCT GTACAAAGAT TTCTTTAAGG GGAAAACGGT GTTTAATCAC 
TGGCTACCAG GACTATGTTA CAGTAACATC ACTTTCCAGC TGGTATCGGA GGCAACTTTT 
AATAAAAGTA CCCTTGTGGA GTACAGTGGT GTGAGCCATG AACCCAAACA GCACAGAACA 
GCACCATATC CACCTCGAAA CATCTCTGTT CGCTTTGTCA ACTTGAACAA GAACAACTGG 
GAGGAGCCGA GCGGGAGCTT CCCCGAGGAC TCGTTCATCA AACCACCGCA AGATTCAATA 
GGAAGAGACA GACGCTTCCA TTTCCCCGAA GAAACTCCGG AGACTCCCCC CAGCAATGTG 
TCCTCCGGTT CTCCCCCCAG CAATGTGTCC TCCGCTTGGC CTGACCCGAA TAGCACAGAC 
TATGAAAGCA CATCACAGCC CTTCTGGTGG GACAGTGCAT CCGCGGCCCC TGAAAACGAG 
GAGGACTTTG TCAGTGCGCT GCCAGCAGAC TATGACACTG AGACCACACT CGATAGGACA 
GAGAAGCCCA CAGCCGACCC TTTCTCTGCC TTCCCTGTGC AGATGACTCT GAGCTGGTTA 
CCACCCAAAC CGCCCACAGC CTTTGATGGC TTCAATATCC TCATAGAGAG GGAAGAGAAC 
TTTACTGACT ATTTGACAGT GGATGAAGAA GCCCATGAAT TCGTTGCAGA ACTGAAGGAG 
CCTGGGAAAT ACAAACTCTC AGTGACAACC TTTAGCTCCT CGGGGGCCTG TGAGACTCGG 
AAAAGCCAGT CAGCAAAATC GCTCAGCTTC TACATCAGCC CCACAGGCGA GTGGATTGAA 
GAACTGACCG AGAAACCTCA GCATGTGAGT GTCCACGTCT TAAGCTCAAC CACCGCCTTG 
ATGTCGTGGA CATCTTCTCA GGAGAACTAC AACAGCACCA TTGTGTCTGT GGTGTCCTTG 
ACCTGCCAGA AACAGAAGGA GAGCCAGCGG CTGGAGAAGC AGTATTGTAC CCAGGTGAAC 
TCAAGCAAAC CTGTAATTGA GAACCTGGTT CCTGGTGCCC AGTACCAGGT TGTGATGTAC 
TTAAGAAAAG GCCCTTTGAT TGGGCCACCT TCCGATCCTG TGACATTTGC GATTGTTCCC 
ACTGGGATCA AAGATTTAAT GCTCTACCCC TTGGGTCCCA CTGCTGTCGT GCTGAGCTGG 
ACCCGACCTA TCCTGGGAGT CTTCAGAAAA TACGTGGTTG AAATGTTCTA CTTCAACCCC 
ACCACCATGA CCTCAGAGTG GACGACCTAC TATGAGATAG CAGCCACAGT TTCCTTAACG 
GCATCCGTGA GAATAGCAAG CCTATTGCCA GCGTGGTACT ACAACTTCCG CGTAACCATG 
GTGACATGGG GAGATCCAGA GCTGAGCTGT TGTGACAGTT CCACCATCAG CTTCATAACA 
GCCCCCGTTG CTCCAGAAAT CACGTCTGTG GAGTACTTCA ACAGCCTGCT GTACATCAGT 
TGGACCTATG GGGATGCCAC CACTGACCTG TCCCACTCTA GAATGCTGCA CTGGATGGTC 
GTTGCAGAAG GGAGGAAGAA AATTAAAAAG AGTGTGACAC GCAATGTCAT GACGGCCATC 
CTTAGCCTGC CTCCAGGAGA TATCTACAAT CTGTCTGTCA CGGCCTGCAC TGAGAGAGGG 
AGCAACACCT CCTTGCCCCG CCTTGTCAAG CTCGAACCAG CCCCTCCGAA GTCACTCTTC 
GCAGTGAACA AAACACAGAC GTCAGTGACC CTGCTGTGGG TTGAGGAGGG TGTTGCTGAT 
TTCTTTGAAG TCTTCTGTCA GCAGCTCGGC TCTGGCCACA ATGGCAAACT CCAGGAGCCA 
GTAGCTGTGT CGTCCCACGT GGTGACCATC TCCAGCCTCC TCCCAGCCAC TGCCTACAAC 
TGCAGTGTCA CCAGCTTCAG CCACGACACT CCCAGTGTCC CTACATTCAT AGCTGTCTCC 
ACAATGGTTA CAGAGGTGAA CCCTAACGTG GTGGTGATCT CGGTGCTGGC CATCCTCAGC 
ACACTTTTAA TTGGACTGCT CTTAGTGACC CTTGTCATTC TCCGAAAGAA GCACCTGCAG 
ATGGCTAGGG AATGTGGAGC TGGCACGTTT GTTAACTTTG CATCCTTAGA AAGGGAAGGG 
AAACTCCCCT ACAGTTGGAG TAAAAATGGC TTAAAGAAGA GGAAACTAAC AAACCCCGTT 
CAGCTGGATG ACTTCGATTC TTACATCAAG GATATGGCCA AGGACTCGGA CTATAAATTC 
TCTCTTCAGT TTGAGGAGTT GAAGTTGATT GGACTGGATA TTCCGCACTT TGCTGCAGAT 
CTACCGCTGA ACCGATGTAA AAACCGCTAC ACAAACATCC TGCCGTATGA CTTTAGCCGG 
GTGAGGCTAG TCTCCATGAA CGAAGAGGAA GGAGCAGACT ACATTAATGC CAACTATATT 
CCTGGATACA ACTCACCCCA GGAGTACATT GCCACCCAGG GTCCCCTGCC AGAAACCAGA 
AATGACTTCT GGAAGATGGT CCTACAACAG AAGTCCCACA TCATCGTCAT GCTCACTCAA 
TGCAATGAGA AAAGGAGGGT AAAATGTGAC CACTACTGGC CATTCACAGA AGAACCCATT 
GCTTATGGGG ACATCACCGT GGAGATGGTC TCTGAGGAAG AGGAGGAGGA CTGGGCCAGT 
AGACACTTCC GGATCAACTA TGCGGACGAA GCGCAGGACG TGATGCATTT TAACTACACA 
GCCTGGCCCG ATCACGGCGT GCCTCCAGCA AACGCCGCCG AGAGCATCCT GCAGTTTGTG 
TTCACAGTGC GACAGCAAGC CGCCAAGAGC AAAGGGCCCA TGATCATCCA CTGCAGTGCG 
GGTGTGGGAC GGACAGGAAC CTTCATTGCC CTGGACAGGC TCCTGCAACA CATTCGAGAT 
CATGAATTTG TGGACATCTT AGGGCTGGTA TCAGAGATGC GCTCATACCG AATGTCAATG 
GTACAGACAG AGGAGCAGTA CATTTTTATC CATCAGTGTG TGCAGCTGAT GTGGCTGAGG 
AAGAAGCAAC AGTTCTGCAT CAGCGACGTC ATCTACGAGA ACGTCAGCAA ATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001157873.1
CDS	388..3984
Translation	MGHLPRGTLGGRRLLPLLGLFVLLKIVTTFHVAVQDDNNIVVSLEASDIVSPASVYVVRVAGESKNYFFEFEEFNSTLPPPVVFKATYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLPVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFNHWLPGLCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRFVNLNKNNWEEPSGSFPEDSFIKPPQDSIGRDRRFHFPEETPETPPSNVSSGSPPSNVSSAWPDPNSTDYESTSQPFWWDSASAAPENEEDFVSALPADYDTETTLDRTEKPTADPFSAFPVQMTLSWLPPKPPTAFDGFNILIEREENFTDYLTVDEEAHEFVAELKEPGKYKLSVTTFSSSGACETRKSQSAKSLSFYISPTGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPILGVFRKYVVEMFYFNPTTMTSEWTTYYEIAATVSLTASVRIASLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDATTDLSHSRMLHWMVVAEGRKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSLPRLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQLGSGHNGKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHDTPSVPTFIAVSTMVTEVNPNVVVISVLAILSTLLIGLLLVTLVILRKKHLQMARECGAGTFVNFASLEREGKLPYSWSKNGLKKRKLTNPVQLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSHIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMVSEEEEEDWASRHFRINYADEAQDVMHFNYTAWPDHGVPPANAAESILQFVFTVRQQAAKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLRKKQQFCISDVIYENVSKS

Target ORF information:

RefSeq Version	NM_001164401.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein tyrosine phosphatase, receptor type, O (Ptpro), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001164401.1

ORF Insert Sequence:

ATGGGGCACC TGCCTAGGGG AACGCTCGGG GGCCGCCGCC TGCTACCTCT GCTCGGGCTC 
TTTGTGCTGC TCAAGATTGT TACGACGTTC CACGTGGCTG TGCAAGATGA CAACAATATC 
GTTGTGTCTT TAGAAGCTTC TGATATAGTC AGCCCAGCAT CTGTGTATGT TGTGAGGGTA 
GCTGGCGAAT CAAAAAACTA TTTCTTCGAA TTTGAGGAAT TTAACAGCAC ATTGCCTCCT 
CCTGTGGTCT TTAAGGCCAC ATATCACGGT CTTTATTACA TAATCACTCT GGTGGTAGTC 
AACGGGAATG TGGTCACCAA ACCATCCAGA TCAATCACCG TGTTGACAAA ACCCTTGCCT 
GTAACCAGTG TGTCTATCTA TGACTATAAA CCTTCTCCTG AGACAGGAGT CCTGTTTGAA 
ATCCATTATC CGGAAAAATA CAATGTGTTC AGCAGAGTGA ACATCAGCTA CTGGGAAGGG 
AGGGACTTCA GGACGATGCT GTACAAAGAT TTCTTTAAGG GGAAAACGGT GTTTAATCAC 
TGGCTACCAG GACTATGTTA CAGTAACATC ACTTTCCAGC TGGTATCGGA GGCAACTTTT 
AATAAAAGTA CCCTTGTGGA GTACAGTGGT GTGAGCCATG AACCCAAACA GCACAGAACA 
GCACCATATC CACCTCGAAA CATCTCTGTT CGCTTTGTCA ACTTGAACAA GAACAACTGG 
GAGGAGCCGA GCGGGAGCTT CCCCGAGGAC TCGTTCATCA AACCACCGCA AGATTCAATA 
GGAAGAGACA GACGCTTCCA TTTCCCCGAA GAAACTCCGG AGACTCCCCC CAGCAATGTG 
TCCTCCGGTT CTCCCCCCAG CAATGTGTCC TCCGCTTGGC CTGACCCGAA TAGCACAGAC 
TATGAAAGCA CATCACAGCC CTTCTGGTGG GACAGTGCAT CCGCGGCCCC TGAAAACGAG 
GAGGACTTTG TCAGTGCGCT GCCAGCAGAC TATGACACTG AGACCACACT CGATAGGACA 
GAGAAGCCCA CAGCCGACCC TTTCTCTGCC TTCCCTGTGC AGATGACTCT GAGCTGGTTA 
CCACCCAAAC CGCCCACAGC CTTTGATGGC TTCAATATCC TCATAGAGAG GGAAGAGAAC 
TTTACTGACT ATTTGACAGT GGATGAAGAA GCCCATGAAT TCGTTGCAGA ACTGAAGGAG 
CCTGGGAAAT ACAAACTCTC AGTGACAACC TTTAGCTCCT CGGGGGCCTG TGAGACTCGG 
AAAAGCCAGT CAGCAAAATC GCTCAGCTTC TACATCAGCC CCACAGGCGA GTGGATTGAA 
GAACTGACCG AGAAACCTCA GCATGTGAGT GTCCACGTCT TAAGCTCAAC CACCGCCTTG 
ATGTCGTGGA CATCTTCTCA GGAGAACTAC AACAGCACCA TTGTGTCTGT GGTGTCCTTG 
ACCTGCCAGA AACAGAAGGA GAGCCAGCGG CTGGAGAAGC AGTATTGTAC CCAGGTGAAC 
TCAAGCAAAC CTGTAATTGA GAACCTGGTT CCTGGTGCCC AGTACCAGGT TGTGATGTAC 
TTAAGAAAAG GCCCTTTGAT TGGGCCACCT TCCGATCCTG TGACATTTGC GATTGTTCCC 
ACTGGGATCA AAGATTTAAT GCTCTACCCC TTGGGTCCCA CTGCTGTCGT GCTGAGCTGG 
ACCCGACCTA TCCTGGGAGT CTTCAGAAAA TACGTGGTTG AAATGTTCTA CTTCAACCCC 
ACCACCATGA CCTCAGAGTG GACGACCTAC TATGAGATAG CAGCCACAGT TTCCTTAACG 
GCATCCGTGA GAATAGCAAG CCTATTGCCA GCGTGGTACT ACAACTTCCG CGTAACCATG 
GTGACATGGG GAGATCCAGA GCTGAGCTGT TGTGACAGTT CCACCATCAG CTTCATAACA 
GCCCCCGTTG CTCCAGAAAT CACGTCTGTG GAGTACTTCA ACAGCCTGCT GTACATCAGT 
TGGACCTATG GGGATGCCAC CACTGACCTG TCCCACTCTA GAATGCTGCA CTGGATGGTC 
GTTGCAGAAG GGAGGAAGAA AATTAAAAAG AGTGTGACAC GCAATGTCAT GACGGCCATC 
CTTAGCCTGC CTCCAGGAGA TATCTACAAT CTGTCTGTCA CGGCCTGCAC TGAGAGAGGG 
AGCAACACCT CCTTGCCCCG CCTTGTCAAG CTCGAACCAG CCCCTCCGAA GTCACTCTTC 
GCAGTGAACA AAACACAGAC GTCAGTGACC CTGCTGTGGG TTGAGGAGGG TGTTGCTGAT 
TTCTTTGAAG TCTTCTGTCA GCAGCTCGGC TCTGGCCACA ATGGCAAACT CCAGGAGCCA 
GTAGCTGTGT CGTCCCACGT GGTGACCATC TCCAGCCTCC TCCCAGCCAC TGCCTACAAC 
TGCAGTGTCA CCAGCTTCAG CCACGACACT CCCAGTGTCC CTACATTCAT AGCTGTCTCC 
ACAATGGTTA CAGAGGTGAA CCCTAACGTG GTGGTGATCT CGGTGCTGGC CATCCTCAGC 
ACACTTTTAA TTGGACTGCT CTTAGTGACC CTTGTCATTC TCCGAAAGAA GCACCTGCAG 
ATGGCTAGGG AATGTGGAGC TGGCACGTTT GTTAACTTTG CATCCTTAGA AAGGGAAGGG 
AAACTCCCCT ACAGTTGGAG TAAAAATGGC TTAAAGAAGA GGAAACTAAC AAACCCCGTT 
CAGCTGGATG ACTTCGATTC TTACATCAAG GATATGGCCA AGGACTCGGA CTATAAATTC 
TCTCTTCAGT TTGAGGAGTT GAAGTTGATT GGACTGGATA TTCCGCACTT TGCTGCAGAT 
CTACCGCTGA ACCGATGTAA AAACCGCTAC ACAAACATCC TGCCGTATGA CTTTAGCCGG 
GTGAGGCTAG TCTCCATGAA CGAAGAGGAA GGAGCAGACT ACATTAATGC CAACTATATT 
CCTGGATACA ACTCACCCCA GGAGTACATT GCCACCCAGG GTCCCCTGCC AGAAACCAGA 
AATGACTTCT GGAAGATGGT CCTACAACAG AAGTCCCACA TCATCGTCAT GCTCACTCAA 
TGCAATGAGA AAAGGAGGGT AAAATGTGAC CACTACTGGC CATTCACAGA AGAACCCATT 
GCTTATGGGG ACATCACCGT GGAGATGGTC TCTGAGGAAG AGGAGGAGGA CTGGGCCAGT 
AGACACTTCC GGATCAACTA TGCGGACGAA GCGCAGGACG TGATGCATTT TAACTACACA 
GCCTGGCCCG ATCACGGCGT GCCTCCAGCA AACGCCGCCG AGAGCATCCT GCAGTTTGTG 
TTCACAGTGC GACAGCAAGC CGCCAAGAGC AAAGGGCCCA TGATCATCCA CTGCAGTGCG 
GGTGTGGGAC GGACAGGAAC CTTCATTGCC CTGGACAGGC TCCTGCAACA CATTCGAGAT 
CATGAATTTG TGGACATCTT AGGGCTGGTA TCAGAGATGC GCTCATACCG AATGTCAATG 
GTACAGACAG AGGAGCAGTA CATTTTTATC CATCAGTGTG TGCAGCTGAT GTGGCTGAGG 
AAGAAGCAAC AGTTCTGCAT CAGCGACGTC ATCTACGAGA ACGTCAGCAA ATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Gastroenterology(2017 Oct)
Memic F,Knoflach V,Morarach K,Sadler R,Laranjeira C,Hjerling-Leffler J,Sundstr?m E,Pachnis V,Marklund U

Identification of Protein Tyrosine Phosphatase Receptor Type O (PTPRO) as a Synaptic Adhesion Molecule that Promotes Synapse Formation.
The Journal of neuroscience : the official journal of the Society for Neuroscience37(41)9828-9843(2017 Oct)
Jiang W,Wei M,Liu M,Pan Y,Cao D,Yang X,Zhang C

The PTPROt tyrosine phosphatase functions as an obligate haploinsufficient tumor suppressor in vivo in B-cell chronic lymphocytic leukemia.
Oncogene36(26)3686-3694(2017 Jun)
Wakim J,Arman E,Becker-Herman S,Kramer MP,Bakos E,Shachar I,Elson A

PTPRO Promotes Oxidized Low-Density Lipoprotein Induced Oxidative Stress and Cell Apoptosis through Toll-Like Receptor 4/Nuclear Factor ?B Pathway.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology42(2)495-505(2017)
Liang C,Wang X,Hu J,Lian X,Zhu T,Zhang H,Gu N,Li J

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Ptpro cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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