Gene Symbol | Ripk2 |
Entrez Gene ID | 192656 |
Full Name | receptor (TNFRSF)-interacting serine-threonine kinase 2 |
Synonyms | 2210420D18Rik,CARD3,CARDIAK,CCK,D4Bwg0615e,RICK,RIP2 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome | |
Summary | This gene encodes a member of the receptor-interacting protein family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain, and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of nuclear factor kappa B and inducer of apoptosis in response to various stimuli. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]. |