Ptpn13 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ptpn13
Entrez Gene ID	19249
Full Name	protein tyrosine phosphatase, non-receptor type 13
Synonyms	AI324989,PTP-BL,PTPL1,Ptpri,RIP
General protein information	Preferred Names protein tyrosine phosphatase, non-receptor type 13 Names tyrosine-protein phosphatase non-receptor type 13 PTP36 protein tyrosine phosphatase DPZPTP protein tyrosine phosphatase PTP-BL protein-tyrosine phosphatase RIP tyrosine phosphatase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5 E5\|5 50.43 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_011204.2	NP_035334.2	tyrosine-protein phosphatase non-receptor type 13

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Ptpn13	NP_001094259.1
Xenopus tropicalis (tropical clawed frog)	ptpn13	XP_002936504.2
Danio rerio (zebrafish)	ptpn13	NP_001083012.2
Pan troglodytes (chimpanzee)	PTPN13	XP_003950411.1
	PTPN13	XP_002808460.1
Mus musculus (house mouse)	Ptpn13	NP_035334.2
Gallus gallus (chicken)	PTPN13	XP_003641237.2
Homo sapiens (human)	PTPN13	NP_542416.1
Canis lupus familiaris (dog)	PTPN13	XP_005639208.1
Bos taurus (cattle)	PTPN13	NP_777015.2

Gene Ontology
Bibliography

Related articles in PubMed

Sporadic Hirschsprung Disease: Mutational Spectrum and Novel Candidate Genes Revealed by Next-generation Sequencing.
Zhang Z, Li Q, Diao M, Liu N, Cheng W, Xiao P, Zou J, Su L, Yu K, Wu J, Li L, Jiang Q
Scientific reports7(1)14796(2017 Nov)

The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation.
Wang Y, Hall RA, Lee M, Kamgar-Parsi A, Bi X, Baudry M
Scientific reports7(1)11771(2017 Sep)

The role of Fas-associated phosphatase 1 in leukemia stem cell persistence during tyrosine kinase inhibitor treatment of chronic myeloid leukemia.
Huang W, Luan CH, Hjort EE, Bei L, Mishra R, Sakamoto KM, Platanias LC, Eklund EA
Leukemia30(7)1502-9(2016 Jul)

Genes Frequently Coexpressed with Hoxc8 Provide Insight into the Discovery of Target Genes.
Kalyani R, Lee JY, Min H, Yoon H, Kim MH
Molecules and cells39(5)395-402(2016 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

contributions of Fap1 to tyrosine kinase inhibitors (TKI)resistance, CML blast crisis, and relapse after TKI discontinuation
Title: The role of Fas-associated phosphatase 1 in leukemia stem cell persistence during tyrosine kinase inhibitor treatment of chronic myeloid leukemia.

The data show that the levels of PTPN13 and beta-catenin must be strictly regulated by extracellular signaling to regulate hematopoietic stem cells attachment to the bone marrow niche and the balance between proliferation and quiescence.
Title: PTPN13 and ?-Catenin Regulate the Quiescence of Hematopoietic Stem Cells and Their Interaction with the Bone Marrow Niche.

The study presents a detailed kinetics analysis of the interaction between PTP-BL PDZ2 domain and a peptide mimicking the PDZ binding motif of APC.
Title: The mechanism of binding of the second PDZ domain from the Protein Tyrosine Phosphatase-BL to the Adenomatous Polyposis Coli tumor suppressor.

SDCCAG3 forms a complex with PTPN13. Interaction of SDCCAG3 with PTPN13 is mediated via the FERM domain of PTPN13 and via the N-terminus of SDCCAG3.
Title: The serologically defined colon cancer antigen-3 interacts with the protein tyrosine phosphatase PTPN13 and is involved in the regulation of cytokinesis.

Since PTPL1 catalytic activity is important for cell transformation, VCP regulation by PTPL1 might be important for tumorigenesis.
Title: Valosin containing protein (VCP/p97) is a novel substrate for the protein tyrosine phosphatase PTPL1.

The following Ptpn13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ptpn13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu20907	NM_011204.2 Latest version!	Mus musculus protein tyrosine phosphatase, non-receptor type 13 (Ptpn13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	30	$1301.30 $1859.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ptpn13 ( NM_011204.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035334.2 Mus musculus protein tyrosine phosphatase, non-receptor type 13 (Ptpn13), mRNA.

Price & Availability↑

CloneID	OMu20907
Clone ID Related Accession (Same CDS sequence)	NM_011204.2
Accession Version	NM_011204.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 7356bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	tyrosine-protein phosphatase non-receptor type 13
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK014577.1, AK080313.1, Z32740.1, CK391553.1, CX202144.1, AK161200.1, AK164471.1 and CF553324.1. On Mar 31, 2007 this sequence version replaced NM_011204.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D83966.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849384 [ECO:0000348] ##Evidence-Data-END##

ATGCATGTGT CACTGGCAGA AGCCCTGGAG GTTCGGGGTG GACCTCTGCA GGAGGAGGAA 
ATATGGGCTG TATTAAATCA GAGTGCTGAA AGCCTGCAAG AAGTATTTAG AAGAGTGAGC 
ATTGCTGACC CTGCTGCGCT GGGCTTCATC ATCTCTCCAT GGTCGCTGCT GTTGCTGCCA 
TCGGGCAGTG TGTCCTTTAC GGATGAAAAT GTCTCCAATC AGGACCTTAG AGCATTCACC 
GCACCGGAGG TTCTTCAGAG CCATTCTCTG ACTTCTCTCG CAGATGTAGA GAAGATCCAT 
ATTTATTCTC TTGGAATGAC ATTGTATTGG GGGGCTGACC ATGAAGTACC TCAAAGCCAG 
CCCATCAAGC TGGGAGACCA TCTTAATAGC ATCCTGCTGG GCATGTGTGA GGATGTCATC 
TATGCTCGGG TGTCGGTTCG GACCGTCCTG GATGCTTGCA GTGCCCACAT CAGGAACAGC 
AACTGCGCGC CTTCGTTTTC CTATGTGAAA CAGTTGGTAA AGCTGGTTCT GGGCAATATT 
TCTGGGACGG ATCCACTTTC CCGTAGCAGT GAACAAAAAC CTGACCGGAG CCAGGCCATT 
CGAGACCGAC TGAGAGGAAA AGGATTGCCC ACAGGAAGAA GCTCCACTTC AGACGCACTA 
GACACACACG AGGCTCCACT CTCTCAGCAG ACCTTTCTTA ACAAAGGGCT TAGTAAGTCT 
ATGGGATTTC TGTCCATCAG AGACACACGA GATGAGGAAG ACTATCTCAA GGATACTCCA 
TCTGATAATA ATTCCAGGCA TGAAGATTCT GAGACTTTCT CTTCCCCTTA CCAGTTCAAA 
ACTAGTACTC CACAGATGGA TGCACTCTCC AAGAAGAAGA CATGGGCTTC CTCCATGGAC 
TTGCTCTGTG CAGCTAACAG AGACATTTCT GGAGAGACGG GCAGGTACCA ACGCTGTGAC 
CCTGAGACAG TGACAGGACG GACGTCCATC ACTCCTAGAA AAAAAGAAGG AAGGTACTCT 
GATGGAAGCA TTGCCTTGGA TATCTTTGGC CCTCAGAAGG TGGAGCCGGT GATCCACACC 
CGAGAACTGC CGACCTCCAC CGCGGTATCA AGCGCTTTGG ACCGAATTCG AGAGAGACAA 
AAGAAACTTC AGGTTCTGAG AGAAGCCATG AATGTAGAAG AGCCAGTTCG AAGATACAAA 
ACTTACCACA GCGATATCTT TAGTATTTCC AGTGAAAGCC CATCTGTTAT TTCCTCGGAA 
TCAGACTTCA GACAAGTAAG AAAAAGTGAA GCTTCCAAGA GGTTTGAATC CAGCAGTGGT 
CTTCCCGGAG TAGATGAAAC TGGCCAGACA CGACCAAGTA GACAATATGA AACATCCCTC 
GAAGGCAACT TGATCAATCA GGACATAATG CTAAGGCGTC AAGAGGAAGA AATGATGCAG 
CTGCAAGCCA GGATGGCTCT CCGACAGTCG CGGCTCAGCC TGTATCCAGG GGACACCGTC 
AAAGCTTCCA TGCTCGACAT CTCTAGAGAC CCCCTAAGGG AAATGGCCCT GGAGACAGCC 
ATGACCCAGA GGAAGCTCAG GAATTTCTTT GGACCTGAGT TTGTGAAGAT GACGGTTGAG 
CCATTTGTAT CTTTGGATTT GCCACGGTCT ATCCTCTCGC AGACCAAGAA GGGGAAGAGT 
GAGGACCAGC GGCGGAAAGT GAACATAAGG CTCCTGAGCG GGCAGCGGCT GGAGCTCACC 
TGCGACACCA AGACCATCTG CAAGGATGTG TTCGACATGG TGGTGGCGCA CATCGGCTTG 
GTGGAGCACC ATTTGTTTGC TCTCGCCACC CGCAAAGAGA ATGAATATTT CTTTGTTGAT 
CCTGACTTAA AATTAACCAA AGTGGCCCCG GAGGGGTGGA AGGAAGAACC GAAGAGAAAG 
GGCAAGGCCG CCGTTGACTT TACGTTGTTT TTCCGAATTA AATTTTTCAT GGATGATGTT 
AGTCTGATAC AACATGACCT CACGTGCCAT CAGTATTACC TTCAGCTGAG GAAAGACCTT 
CTGGATGAGA GGGTGCACTG TGACGACGAG GCCGCCCTGC TTCTTGCATC CTTGGCTCTC 
CAGGCAGAGT ATGGAGATTA TCAGCCAGAG GTTCATGGCG TGTCCTACTT TCGCCTGGAA 
CATTACCTGC CCGCCAGGGT GATGGAGAAG CTGGACGTGT CCTACATTAA AGAAGAGTTA 
CCCAAACTGC ATAACACCTA TGCAGGCGCT TCCGAGAAGG AGACAGAGCT AGAGTTCTTA 
AAGGTCTGCC AAAGGCTGAC AGAGTATGGA GTTCACTTTC ACCGGGTACA CCCTGAGAAG 
AAGTCACAGA CAGGGATACT GCTGGGGGTC TGTTCCAAAG GTGTGCTGGT CTTTGAGGTT 
CACAATGGAG TCCGTGCCTT GGTCCTTCGC TTCCCGTGGA GGGAAACAAA AAAGATTTCC 
TTTTCAAAGA AGAAAATCAC ATTACAGAAC ACGTCAGATG GAATCAAGCA TGCGTTCCAG 
ACGGACAGCA GCAAGGCATG CCAGTACCTG CTGCACCTGT GCTCCTCCCA GCACAAGTTC 
CAATTGCAGA TGAGGGCGCG GCAGAGCAAC CAGGATGCCC AAGACATAGA GAGAGCTTCG 
TTTAGGAGCC TGAACCTGCA AGCAGAGTCT GTTAGAGGAT TTAATATGGG CCGCGCAATC 
AGCACGGGCA GTCTGGCCAG CAGCACCATC AACAAACTTG CCGTCCGACC CCTGTCAGTT 
CAAGCTGAGA TTCTGAAGAG GCTGTCCAGC TCAGAGTGGT CGCTTTACCA GCCCCTGCAG 
AACAGTTCAA AAGAGAAGAC TGACAAAGCT TCCTGGGAGG AAAAGCCTAG AGGGATGAGC 
AAATCGTATC ACGATCTCAG TCAGGCCTCT CTCTGTCCTC ACCGGAAACA GGTCATTAAC 
ATGGAGGCCC TCCCACAAGC CTTTGCGGAG CTGGTGGGAA AACCCTTGTA CCCGATGGCA 
AGATCTGACA CAGAGTCACT GGCAGGACTC CCAAAGCTTG ATAATTCAAA GTCTGTTGCC 
AGTTTAAATA GAAGCCCCGA AAGGAGGAAC CATGAATCAG ACTCATCCAC TGAAGACCCT 
GGCCAAGCAT ATGTTGTAGG AATGAGTTTG CCTAGCTCTG GAAAATCTTC ATCCCAAGTC 
CCCTTTAAAG ACAATGATAC ACTGCACAAA AGATGGAGCA TTGTTTCGTC ACCAGAAAGG 
GAGATCACAC TGGTGAACCT GAAGAAAGAT CCAAAACACG GCTTAGGATT TCAAATTATC 
GGTGGGGAAA AAATGGGAAG ACTGGATCTA GGAGTGTTTA TCAGTGCAGT TACCCCTGGA 
GGACCTGCTG ACCTGGATGG ATGCTTAAAG CCTGGAGACC GTTTGATATC TGTGAACAGT 
GTGAGTCTGG AAGGGGTCAG TCACCACGCT GCAGTGGACA TTCTGCAGAA TGCACCTGAA 
GATGTGACAC TTGTCATCTC CCAGCCAAAA GAAAAACCGT CCAAAGTGCC TTCTACTCCT 
GTTCATTTTG CCAATGGGAT GAAAAGCTAC ACAAAGAAAC CGGCATACAT GCAGGACAGT 
GCTATGGACC CATCAGAGGA CCAGCCCTGG CCACGGGGTA CTCTGAGGCA CATCCCAGAG 
AGTCCCTTCG GGCTGTCTGG GGGCCTGCGG GAGGGAAGCC TCAGTTCCCA AGATTCCAGG 
ACTGAAAGTG CCAGCCTATC CCAGAGCCAA GTCAACGGCT TCTTTGCCAG CCACTTAGGC 
GACAGAGGCT GGCAGGAACC ACAGCATAGC AGCCCATCGC CATCTGTGAC AACCAAGGTC 
AACGAGAAGA CCTTCTCCGA CAGTAACCGA AGCAAGGCCA AGCGGCGAGG CATCTCCGAT 
TTGATTGAAC ACCTCGACTG TGCTGATTCC GACAAAGACG ATTCCACTTA CACCAGCAGT 
CAAGACCATC AAACGTCAAA ACAGGAACCT TCCTCCTCAC TGAGTACATC GAACAAAACG 
AGCTTTCCAA CCTCGTCTGC GTCACCTCCT AAGCCCGGAG ACACGTTTGA GGTTGAGCTG 
GCTAAAACTG ATGGCAGCCT GGGGATAAGT GTCACGGGAG GTGTGAATAC CAGCGTCCGA 
CATGGTGGTA TTTATGTGAA AGCCATTATT CCCAAAGGAG CGGCAGAGTC AGATGGCAGA 
ATTCACAAAG GTGATCGTGT GCTGGCTGTT AATGGAGTCA GTCTGGAAGG AGCTACCCAC 
AAGCAAGCTG TGGAAACGTT AAGAAACACA GGGCAGGTGG TCCATCTGTT GTTAGAAAAG 
GGGCAGGTGC CAACATCTAG GGAACGGGAT CCTGCAGGCC CACAGAGCCC CCCTCCAGAC 
CAAGACGCCC AAAGACAAGC CCCGGAAAAG GTGGCGAAGC AAACACCCCA TGTCAAAGAC 
TACAGCTTTG TTACTGAAGA TAATACATTT GAGGTCAAGC TGTTTAAAAA TAGCTCAGGC 
CTTGGATTCA GTTTTTCTCG GGAAGATAAT CTTATACCAG AACAAATAAA TGGCAGCATA 
GTAAGGGTTA AAAAGCTCTT CCCTGGACAG CCGGCAGCAG AAAGTGGGAA AATCGATGTT 
GGAGATGTTA TATTGAAAGT TAACGGAGCC CCCTTGAAGG GACTGTCTCA GCAGGACGTC 
ATCTCTGCTC TCAGGGGAAC AGCTCCAGAA GTGTCCTTGC TTCTCTGCAG ACCGGCACCT 
GGTGTGCTAC CAGAAATCGA TACTACATTT TTGAACCCAC TCTACTCTCC AGCAAACTCA 
TTTCTAAACA GCAGTAAAGA GACTTCGCAG CCATCATCCT CAGTAGAGCA GGGTGCCAGC 
TCGGACGACA ATGGGGTGTC TGGCAAAACC AAGAACCATT GCAGGGCTCC ATCCAGGAGA 
GAGAGTTACA GCGACCACAG CGAGAGTGGA GAGGATGACT CCGTGAGAGC ACCAGCCAAG 
ATGCCAAATG TGACCCGAGT GGCAGCCTTT CCACACGAAG CACCGAGAAG CCAGGAAGAG 
TCCATATGTG CCATGTTTTA CCTCCCTCGG AAAATACCCG GAAAGCTGGA GTCCGAGAGC 
AGCCATCCTC CTCCACTGGA CGTGAGCCCT GGACAGACGT GCCAGCCCCC GGCAGAGTGT 
GCTCCGTCTG ACGCCACTGG CAAACACTTT ACACATCTTG CCTCTCAGCT GAGCAAAGAG 
GAAAACATAA CAACCTTGAA AAATGACTTG GGAAACCACC TTGAGGATTC TGAGCTGGAA 
GTAGAGCTTC TCATTACCCT GGTTAAATCA GAAAAAGGAA GTCTGGGCTT TACAGTAACC 
AAAGGCAGTC AGAGTATTGG TTGTTATGTC CATGATGTCA TACAGGATCC AGCCAAAGGT 
GACGGAAGGC TAAAGGCTGG AGACCGGCTT ATAAAGGTTA ATGATACAGA CGTTACAAAC 
ATGACCCACA CAGATGCAGT GAATCTGCTG CGAGCCGCAC CCAAAACAGT CAGATTAGTT 
CTTGGGCGGA TTCTGGAGTT ACCCAGGATG CCAGTATTTC CCCATCTGCT GCCCGACATT 
ACAGTCACAT GCCACGGAGA GGAGTTAGGA TTTTCCCTGT CTGGAGGTCA AGGCAGTCCA 
CATGGAGTGG TGTATATTAG TGATATCAAC CCAAGGTCAG CTGCAGCTGT TGACGGTAGT 
CTCCAGCTAT TAGACATCAT CCATTATGTG AACGGAGTCA GCACACAAGG AATGACCTTG 
GAAGATGCAA ACAGGGCATT GGACCTGTCA CTTCCTTCAG TGGTGCTGAA AGTAACAAGA 
GACGGTTGTC CAGTGGTGCC TACAACAAGA GCTGCCATTT CTGCGCCCAG GTTCACCAAA 
GCCAACGGCC TAACCAGCAT GGAGCCTTCT GGACAGCCTG CACTCATGCC CAAGAACTCC 
TTCTCCAAGG TTAACGGGGA AGGAGTACAT GAAGCTGTGT GCCCTGCAGG AGAAGGCTCG 
TCTTCTCAGA TGAAGGAGTC AGCAGGCCTG ACTGAAACCA AAGAATCTAA CTCCCGGGAT 
GATGACATCT ATGATGATCC TCAAGAAGCT GAAGTTATCC AGTCCTTGCT GGATGTTGTG 
GACGAGGAAG CACAGAACCT CTTAAACCAG AGGCATGCCA CCAGAAGAGC CTGTTCTCCA 
GATCCACTGA GGACGAATGG GGAGGCACCA GAAGAAGGAG ATACCGACTA TGATGGGTCT 
CCGCTACCTG AGGACGTCCC TGAGTCAGTG AGCAGCGGAG AAGGAAAAGT AGACCTTGCA 
AGCTTAACTG CAGCATCACA AGAAGAGAAG CCCATCGAAG AGGACGCCAC GCAGGAAAGC 
AGAAACTCGA CAACGGAGAC AACAGACGGT GAAGATTCCA GCAAAGATCC CCCCTTTCTG 
ACGAATGAGG AGCTGGCAGC CCTGCCGGTG GTCAGAGTCC CTCCCTCTGG CAAGTACACG 
GGCACACAGC TGCAGGCCAC CATCCGCACG CTGCAGGGCT TGCTCGACCA AGGGATCCCT 
TCTAAGGAGC TGGAGAACCT TCAAGAATTA AAACCTTTGG ATCAGTGTCT GATTGGACAG 
ACAAAGGAAA ACCGCAGGAA GAACAGATAC AAAAATATCC TTCCCTATGA CACCACAAGA 
GTGCCTCTTG GAGATGAAGG TGGATACATC AATGCCAGTT TCATCAGGAT CCCGGTGGGG 
ACCCAGGAAT TCGTGTACAT TGCCTGCCAG GGGCCGTTGC CCACCACTGT GGGGGATTTT 
TGGCAGATGG TTTGGGAGCA GAACTCCACG GTGATAGCAA TGATGACGCA GGAGGTGGAA 
GGAGAAAAGA TCAAATGCCA GCGGTACTGG CCAAGCATCC TGGGCACAAC CACCATGGCC 
AACGAGAGGC TGCGCCTGGC CCTCCTGAGG ATGCAGCAGC TGAAGGGCTT CATCGTGCGG 
GTGATGGCCC TGGAGGATAT TCAGACAGGG GAGGTGCGAC ATATTTCTCA TCTGAATTTC 
ACTGCCTGGC CAGACCACGA TACACCGTCG CAGCCAGACG ACCTGCTCAC ATTCATCTCC 
TACATGAGAC ACATCCGTAG GTCGGGCCCA GTCATCACAC ACTGCAGCGC TGGCATTGGA 
CGCTCAGGAA CCCTCATTTG CATAGACGTG GTCCTAGGCT TAATCAGCCA GGATCTGGAA 
TTCGACATCT CTGACCTAGT GCGCTGCATG AGGCTTCAGA GGCACGGCAT GGTGCAGACC 
GAGGGTCAGT ATGTCTTCTG CTATCAAGTC ATCCTCTATG TCCTGACTCA TCTTCAGGCT 
GAAGAGCAGA AGGCACAGCC AGGGCTCCCA CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035334.2
CDS	351..7706
Translation	MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQEVFRRVSIADPAALGFIISPWSLLLLPSGSVSFTDENVSNQDLRAFTAPEVLQSHSLTSLADVEKIHIYSLGMTLYWGADHEVPQSQPIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKQLVKLVLGNISGTDPLSRSSEQKPDRSQAIRDRLRGKGLPTGRSSTSDALDTHEAPLSQQTFLNKGLSKSMGFLSIRDTRDEEDYLKDTPSDNNSRHEDSETFSSPYQFKTSTPQMDALSKKKTWASSMDLLCAANRDISGETGRYQRCDPETVTGRTSITPRKKEGRYSDGSIALDIFGPQKVEPVIHTRELPTSTAVSSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHSDIFSISSESPSVISSESDFRQVRKSEASKRFESSSGLPGVDETGQTRPSRQYETSLEGNLINQDIMLRRQEEEMMQLQARMALRQSRLSLYPGDTVKASMLDISRDPLREMALETAMTQRKLRNFFGPEFVKMTVEPFVSLDLPRSILSQTKKGKSEDQRRKVNIRLLSGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALATRKENEYFFVDPDLKLTKVAPEGWKEEPKRKGKAAVDFTLFFRIKFFMDDVSLIQHDLTCHQYYLQLRKDLLDERVHCDDEAALLLASLALQAEYGDYQPEVHGVSYFRLEHYLPARVMEKLDVSYIKEELPKLHNTYAGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRALVLRFPWRETKKISFSKKKITLQNTSDGIKHAFQTDSSKACQYLLHLCSSQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTGSLASSTINKLAVRPLSVQAEILKRLSSSEWSLYQPLQNSSKEKTDKASWEEKPRGMSKSYHDLSQASLCPHRKQVINMEALPQAFAELVGKPLYPMARSDTESLAGLPKLDNSKSVASLNRSPERRNHESDSSTEDPGQAYVVGMSLPSSGKSSSQVPFKDNDTLHKRWSIVSSPEREITLVNLKKDPKHGLGFQIIGGEKMGRLDLGVFISAVTPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAVDILQNAPEDVTLVISQPKEKPSKVPSTPVHFANGMKSYTKKPAYMQDSAMDPSEDQPWPRGTLRHIPESPFGLSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLGDRGWQEPQHSSPSPSVTTKVNEKTFSDSNRSKAKRRGISDLIEHLDCADSDKDDSTYTSSQDHQTSKQEPSSSLSTSNKTSFPTSSASPPKPGDTFEVELAKTDGSLGISVTGGVNTSVRHGGIYVKAIIPKGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQVPTSRERDPAGPQSPPPDQDAQRQAPEKVAKQTPHVKDYSFVTEDNTFEVKLFKNSSGLGFSFSREDNLIPEQINGSIVRVKKLFPGQPAAESGKIDVGDVILKVNGAPLKGLSQQDVISALRGTAPEVSLLLCRPAPGVLPEIDTTFLNPLYSPANSFLNSSKETSQPSSSVEQGASSDDNGVSGKTKNHCRAPSRRESYSDHSESGEDDSVRAPAKMPNVTRVAAFPHEAPRSQEESICAMFYLPRKIPGKLESESSHPPPLDVSPGQTCQPPAECAPSDATGKHFTHLASQLSKEENITTLKNDLGNHLEDSELEVELLITLVKSEKGSLGFTVTKGSQSIGCYVHDVIQDPAKGDGRLKAGDRLIKVNDTDVTNMTHTDAVNLLRAAPKTVRLVLGRILELPRMPVFPHLLPDITVTCHGEELGFSLSGGQGSPHGVVYISDINPRSAAAVDGSLQLLDIIHYVNGVSTQGMTLEDANRALDLSLPSVVLKVTRDGCPVVPTTRAAISAPRFTKANGLTSMEPSGQPALMPKNSFSKVNGEGVHEAVCPAGEGSSSQMKESAGLTETKESNSRDDDIYDDPQEAEVIQSLLDVVDEEAQNLLNQRHATRRACSPDPLRTNGEAPEEGDTDYDGSPLPEDVPESVSSGEGKVDLASLTAASQEEKPIEEDATQESRNSTTETTDGEDSSKDPPFLTNEELAALPVVRVPPSGKYTGTQLQATIRTLQGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDTTRVPLGDEGGYINASFIRIPVGTQEFVYIACQGPLPTTVGDFWQMVWEQNSTVIAMMTQEVEGEKIKCQRYWPSILGTTTMANERLRLALLRMQQLKGFIVRVMALEDIQTGEVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIRRSGPVITHCSAGIGRSGTLICIDVVLGLISQDLEFDISDLVRCMRLQRHGMVQTEGQYVFCYQVILYVLTHLQAEEQKAQPGLPQ

Target ORF information:

RefSeq Version	NM_011204.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein tyrosine phosphatase, non-receptor type 13 (Ptpn13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011204.2

ORF Insert Sequence:

ATGCATGTGT CACTGGCAGA AGCCCTGGAG GTTCGGGGTG GACCTCTGCA GGAGGAGGAA 
ATATGGGCTG TATTAAATCA GAGTGCTGAA AGCCTGCAAG AAGTATTTAG AAGAGTGAGC 
ATTGCTGACC CTGCTGCGCT GGGCTTCATC ATCTCTCCAT GGTCGCTGCT GTTGCTGCCA 
TCGGGCAGTG TGTCCTTTAC GGATGAAAAT GTCTCCAATC AGGACCTTAG AGCATTCACC 
GCACCGGAGG TTCTTCAGAG CCATTCTCTG ACTTCTCTCG CAGATGTAGA GAAGATCCAT 
ATTTATTCTC TTGGAATGAC ATTGTATTGG GGGGCTGACC ATGAAGTACC TCAAAGCCAG 
CCCATCAAGC TGGGAGACCA TCTTAATAGC ATCCTGCTGG GCATGTGTGA GGATGTCATC 
TATGCTCGGG TGTCGGTTCG GACCGTCCTG GATGCTTGCA GTGCCCACAT CAGGAACAGC 
AACTGCGCGC CTTCGTTTTC CTATGTGAAA CAGTTGGTAA AGCTGGTTCT GGGCAATATT 
TCTGGGACGG ATCCACTTTC CCGTAGCAGT GAACAAAAAC CTGACCGGAG CCAGGCCATT 
CGAGACCGAC TGAGAGGAAA AGGATTGCCC ACAGGAAGAA GCTCCACTTC AGACGCACTA 
GACACACACG AGGCTCCACT CTCTCAGCAG ACCTTTCTTA ACAAAGGGCT TAGTAAGTCT 
ATGGGATTTC TGTCCATCAG AGACACACGA GATGAGGAAG ACTATCTCAA GGATACTCCA 
TCTGATAATA ATTCCAGGCA TGAAGATTCT GAGACTTTCT CTTCCCCTTA CCAGTTCAAA 
ACTAGTACTC CACAGATGGA TGCACTCTCC AAGAAGAAGA CATGGGCTTC CTCCATGGAC 
TTGCTCTGTG CAGCTAACAG AGACATTTCT GGAGAGACGG GCAGGTACCA ACGCTGTGAC 
CCTGAGACAG TGACAGGACG GACGTCCATC ACTCCTAGAA AAAAAGAAGG AAGGTACTCT 
GATGGAAGCA TTGCCTTGGA TATCTTTGGC CCTCAGAAGG TGGAGCCGGT GATCCACACC 
CGAGAACTGC CGACCTCCAC CGCGGTATCA AGCGCTTTGG ACCGAATTCG AGAGAGACAA 
AAGAAACTTC AGGTTCTGAG AGAAGCCATG AATGTAGAAG AGCCAGTTCG AAGATACAAA 
ACTTACCACA GCGATATCTT TAGTATTTCC AGTGAAAGCC CATCTGTTAT TTCCTCGGAA 
TCAGACTTCA GACAAGTAAG AAAAAGTGAA GCTTCCAAGA GGTTTGAATC CAGCAGTGGT 
CTTCCCGGAG TAGATGAAAC TGGCCAGACA CGACCAAGTA GACAATATGA AACATCCCTC 
GAAGGCAACT TGATCAATCA GGACATAATG CTAAGGCGTC AAGAGGAAGA AATGATGCAG 
CTGCAAGCCA GGATGGCTCT CCGACAGTCG CGGCTCAGCC TGTATCCAGG GGACACCGTC 
AAAGCTTCCA TGCTCGACAT CTCTAGAGAC CCCCTAAGGG AAATGGCCCT GGAGACAGCC 
ATGACCCAGA GGAAGCTCAG GAATTTCTTT GGACCTGAGT TTGTGAAGAT GACGGTTGAG 
CCATTTGTAT CTTTGGATTT GCCACGGTCT ATCCTCTCGC AGACCAAGAA GGGGAAGAGT 
GAGGACCAGC GGCGGAAAGT GAACATAAGG CTCCTGAGCG GGCAGCGGCT GGAGCTCACC 
TGCGACACCA AGACCATCTG CAAGGATGTG TTCGACATGG TGGTGGCGCA CATCGGCTTG 
GTGGAGCACC ATTTGTTTGC TCTCGCCACC CGCAAAGAGA ATGAATATTT CTTTGTTGAT 
CCTGACTTAA AATTAACCAA AGTGGCCCCG GAGGGGTGGA AGGAAGAACC GAAGAGAAAG 
GGCAAGGCCG CCGTTGACTT TACGTTGTTT TTCCGAATTA AATTTTTCAT GGATGATGTT 
AGTCTGATAC AACATGACCT CACGTGCCAT CAGTATTACC TTCAGCTGAG GAAAGACCTT 
CTGGATGAGA GGGTGCACTG TGACGACGAG GCCGCCCTGC TTCTTGCATC CTTGGCTCTC 
CAGGCAGAGT ATGGAGATTA TCAGCCAGAG GTTCATGGCG TGTCCTACTT TCGCCTGGAA 
CATTACCTGC CCGCCAGGGT GATGGAGAAG CTGGACGTGT CCTACATTAA AGAAGAGTTA 
CCCAAACTGC ATAACACCTA TGCAGGCGCT TCCGAGAAGG AGACAGAGCT AGAGTTCTTA 
AAGGTCTGCC AAAGGCTGAC AGAGTATGGA GTTCACTTTC ACCGGGTACA CCCTGAGAAG 
AAGTCACAGA CAGGGATACT GCTGGGGGTC TGTTCCAAAG GTGTGCTGGT CTTTGAGGTT 
CACAATGGAG TCCGTGCCTT GGTCCTTCGC TTCCCGTGGA GGGAAACAAA AAAGATTTCC 
TTTTCAAAGA AGAAAATCAC ATTACAGAAC ACGTCAGATG GAATCAAGCA TGCGTTCCAG 
ACGGACAGCA GCAAGGCATG CCAGTACCTG CTGCACCTGT GCTCCTCCCA GCACAAGTTC 
CAATTGCAGA TGAGGGCGCG GCAGAGCAAC CAGGATGCCC AAGACATAGA GAGAGCTTCG 
TTTAGGAGCC TGAACCTGCA AGCAGAGTCT GTTAGAGGAT TTAATATGGG CCGCGCAATC 
AGCACGGGCA GTCTGGCCAG CAGCACCATC AACAAACTTG CCGTCCGACC CCTGTCAGTT 
CAAGCTGAGA TTCTGAAGAG GCTGTCCAGC TCAGAGTGGT CGCTTTACCA GCCCCTGCAG 
AACAGTTCAA AAGAGAAGAC TGACAAAGCT TCCTGGGAGG AAAAGCCTAG AGGGATGAGC 
AAATCGTATC ACGATCTCAG TCAGGCCTCT CTCTGTCCTC ACCGGAAACA GGTCATTAAC 
ATGGAGGCCC TCCCACAAGC CTTTGCGGAG CTGGTGGGAA AACCCTTGTA CCCGATGGCA 
AGATCTGACA CAGAGTCACT GGCAGGACTC CCAAAGCTTG ATAATTCAAA GTCTGTTGCC 
AGTTTAAATA GAAGCCCCGA AAGGAGGAAC CATGAATCAG ACTCATCCAC TGAAGACCCT 
GGCCAAGCAT ATGTTGTAGG AATGAGTTTG CCTAGCTCTG GAAAATCTTC ATCCCAAGTC 
CCCTTTAAAG ACAATGATAC ACTGCACAAA AGATGGAGCA TTGTTTCGTC ACCAGAAAGG 
GAGATCACAC TGGTGAACCT GAAGAAAGAT CCAAAACACG GCTTAGGATT TCAAATTATC 
GGTGGGGAAA AAATGGGAAG ACTGGATCTA GGAGTGTTTA TCAGTGCAGT TACCCCTGGA 
GGACCTGCTG ACCTGGATGG ATGCTTAAAG CCTGGAGACC GTTTGATATC TGTGAACAGT 
GTGAGTCTGG AAGGGGTCAG TCACCACGCT GCAGTGGACA TTCTGCAGAA TGCACCTGAA 
GATGTGACAC TTGTCATCTC CCAGCCAAAA GAAAAACCGT CCAAAGTGCC TTCTACTCCT 
GTTCATTTTG CCAATGGGAT GAAAAGCTAC ACAAAGAAAC CGGCATACAT GCAGGACAGT 
GCTATGGACC CATCAGAGGA CCAGCCCTGG CCACGGGGTA CTCTGAGGCA CATCCCAGAG 
AGTCCCTTCG GGCTGTCTGG GGGCCTGCGG GAGGGAAGCC TCAGTTCCCA AGATTCCAGG 
ACTGAAAGTG CCAGCCTATC CCAGAGCCAA GTCAACGGCT TCTTTGCCAG CCACTTAGGC 
GACAGAGGCT GGCAGGAACC ACAGCATAGC AGCCCATCGC CATCTGTGAC AACCAAGGTC 
AACGAGAAGA CCTTCTCCGA CAGTAACCGA AGCAAGGCCA AGCGGCGAGG CATCTCCGAT 
TTGATTGAAC ACCTCGACTG TGCTGATTCC GACAAAGACG ATTCCACTTA CACCAGCAGT 
CAAGACCATC AAACGTCAAA ACAGGAACCT TCCTCCTCAC TGAGTACATC GAACAAAACG 
AGCTTTCCAA CCTCGTCTGC GTCACCTCCT AAGCCCGGAG ACACGTTTGA GGTTGAGCTG 
GCTAAAACTG ATGGCAGCCT GGGGATAAGT GTCACGGGAG GTGTGAATAC CAGCGTCCGA 
CATGGTGGTA TTTATGTGAA AGCCATTATT CCCAAAGGAG CGGCAGAGTC AGATGGCAGA 
ATTCACAAAG GTGATCGTGT GCTGGCTGTT AATGGAGTCA GTCTGGAAGG AGCTACCCAC 
AAGCAAGCTG TGGAAACGTT AAGAAACACA GGGCAGGTGG TCCATCTGTT GTTAGAAAAG 
GGGCAGGTGC CAACATCTAG GGAACGGGAT CCTGCAGGCC CACAGAGCCC CCCTCCAGAC 
CAAGACGCCC AAAGACAAGC CCCGGAAAAG GTGGCGAAGC AAACACCCCA TGTCAAAGAC 
TACAGCTTTG TTACTGAAGA TAATACATTT GAGGTCAAGC TGTTTAAAAA TAGCTCAGGC 
CTTGGATTCA GTTTTTCTCG GGAAGATAAT CTTATACCAG AACAAATAAA TGGCAGCATA 
GTAAGGGTTA AAAAGCTCTT CCCTGGACAG CCGGCAGCAG AAAGTGGGAA AATCGATGTT 
GGAGATGTTA TATTGAAAGT TAACGGAGCC CCCTTGAAGG GACTGTCTCA GCAGGACGTC 
ATCTCTGCTC TCAGGGGAAC AGCTCCAGAA GTGTCCTTGC TTCTCTGCAG ACCGGCACCT 
GGTGTGCTAC CAGAAATCGA TACTACATTT TTGAACCCAC TCTACTCTCC AGCAAACTCA 
TTTCTAAACA GCAGTAAAGA GACTTCGCAG CCATCATCCT CAGTAGAGCA GGGTGCCAGC 
TCGGACGACA ATGGGGTGTC TGGCAAAACC AAGAACCATT GCAGGGCTCC ATCCAGGAGA 
GAGAGTTACA GCGACCACAG CGAGAGTGGA GAGGATGACT CCGTGAGAGC ACCAGCCAAG 
ATGCCAAATG TGACCCGAGT GGCAGCCTTT CCACACGAAG CACCGAGAAG CCAGGAAGAG 
TCCATATGTG CCATGTTTTA CCTCCCTCGG AAAATACCCG GAAAGCTGGA GTCCGAGAGC 
AGCCATCCTC CTCCACTGGA CGTGAGCCCT GGACAGACGT GCCAGCCCCC GGCAGAGTGT 
GCTCCGTCTG ACGCCACTGG CAAACACTTT ACACATCTTG CCTCTCAGCT GAGCAAAGAG 
GAAAACATAA CAACCTTGAA AAATGACTTG GGAAACCACC TTGAGGATTC TGAGCTGGAA 
GTAGAGCTTC TCATTACCCT GGTTAAATCA GAAAAAGGAA GTCTGGGCTT TACAGTAACC 
AAAGGCAGTC AGAGTATTGG TTGTTATGTC CATGATGTCA TACAGGATCC AGCCAAAGGT 
GACGGAAGGC TAAAGGCTGG AGACCGGCTT ATAAAGGTTA ATGATACAGA CGTTACAAAC 
ATGACCCACA CAGATGCAGT GAATCTGCTG CGAGCCGCAC CCAAAACAGT CAGATTAGTT 
CTTGGGCGGA TTCTGGAGTT ACCCAGGATG CCAGTATTTC CCCATCTGCT GCCCGACATT 
ACAGTCACAT GCCACGGAGA GGAGTTAGGA TTTTCCCTGT CTGGAGGTCA AGGCAGTCCA 
CATGGAGTGG TGTATATTAG TGATATCAAC CCAAGGTCAG CTGCAGCTGT TGACGGTAGT 
CTCCAGCTAT TAGACATCAT CCATTATGTG AACGGAGTCA GCACACAAGG AATGACCTTG 
GAAGATGCAA ACAGGGCATT GGACCTGTCA CTTCCTTCAG TGGTGCTGAA AGTAACAAGA 
GACGGTTGTC CAGTGGTGCC TACAACAAGA GCTGCCATTT CTGCGCCCAG GTTCACCAAA 
GCCAACGGCC TAACCAGCAT GGAGCCTTCT GGACAGCCTG CACTCATGCC CAAGAACTCC 
TTCTCCAAGG TTAACGGGGA AGGAGTACAT GAAGCTGTGT GCCCTGCAGG AGAAGGCTCG 
TCTTCTCAGA TGAAGGAGTC AGCAGGCCTG ACTGAAACCA AAGAATCTAA CTCCCGGGAT 
GATGACATCT ATGATGATCC TCAAGAAGCT GAAGTTATCC AGTCCTTGCT GGATGTTGTG 
GACGAGGAAG CACAGAACCT CTTAAACCAG AGGCATGCCA CCAGAAGAGC CTGTTCTCCA 
GATCCACTGA GGACGAATGG GGAGGCACCA GAAGAAGGAG ATACCGACTA TGATGGGTCT 
CCGCTACCTG AGGACGTCCC TGAGTCAGTG AGCAGCGGAG AAGGAAAAGT AGACCTTGCA 
AGCTTAACTG CAGCATCACA AGAAGAGAAG CCCATCGAAG AGGACGCCAC GCAGGAAAGC 
AGAAACTCGA CAACGGAGAC AACAGACGGT GAAGATTCCA GCAAAGATCC CCCCTTTCTG 
ACGAATGAGG AGCTGGCAGC CCTGCCGGTG GTCAGAGTCC CTCCCTCTGG CAAGTACACG 
GGCACACAGC TGCAGGCCAC CATCCGCACG CTGCAGGGCT TGCTCGACCA AGGGATCCCT 
TCTAAGGAGC TGGAGAACCT TCAAGAATTA AAACCTTTGG ATCAGTGTCT GATTGGACAG 
ACAAAGGAAA ACCGCAGGAA GAACAGATAC AAAAATATCC TTCCCTATGA CACCACAAGA 
GTGCCTCTTG GAGATGAAGG TGGATACATC AATGCCAGTT TCATCAGGAT CCCGGTGGGG 
ACCCAGGAAT TCGTGTACAT TGCCTGCCAG GGGCCGTTGC CCACCACTGT GGGGGATTTT 
TGGCAGATGG TTTGGGAGCA GAACTCCACG GTGATAGCAA TGATGACGCA GGAGGTGGAA 
GGAGAAAAGA TCAAATGCCA GCGGTACTGG CCAAGCATCC TGGGCACAAC CACCATGGCC 
AACGAGAGGC TGCGCCTGGC CCTCCTGAGG ATGCAGCAGC TGAAGGGCTT CATCGTGCGG 
GTGATGGCCC TGGAGGATAT TCAGACAGGG GAGGTGCGAC ATATTTCTCA TCTGAATTTC 
ACTGCCTGGC CAGACCACGA TACACCGTCG CAGCCAGACG ACCTGCTCAC ATTCATCTCC 
TACATGAGAC ACATCCGTAG GTCGGGCCCA GTCATCACAC ACTGCAGCGC TGGCATTGGA 
CGCTCAGGAA CCCTCATTTG CATAGACGTG GTCCTAGGCT TAATCAGCCA GGATCTGGAA 
TTCGACATCT CTGACCTAGT GCGCTGCATG AGGCTTCAGA GGCACGGCAT GGTGCAGACC 
GAGGGTCAGT ATGTCTTCTG CTATCAAGTC ATCCTCTATG TCCTGACTCA TCTTCAGGCT 
GAAGAGCAGA AGGCACAGCC AGGGCTCCCA CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Sporadic Hirschsprung Disease: Mutational Spectrum and Novel Candidate Genes Revealed by Next-generation Sequencing.
Scientific reports7(1)14796(2017 Nov)
Zhang Z,Li Q,Diao M,Liu N,Cheng W,Xiao P,Zou J,Su L,Yu K,Wu J,Li L,Jiang Q

The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation.
Scientific reports7(1)11771(2017 Sep)
Wang Y,Hall RA,Lee M,Kamgar-Parsi A,Bi X,Baudry M

The role of Fas-associated phosphatase 1 in leukemia stem cell persistence during tyrosine kinase inhibitor treatment of chronic myeloid leukemia.
Leukemia30(7)1502-9(2016 Jul)
Huang W,Luan CH,Hjort EE,Bei L,Mishra R,Sakamoto KM,Platanias LC,Eklund EA

Genes Frequently Coexpressed with Hoxc8 Provide Insight into the Discovery of Target Genes.
Molecules and cells39(5)395-402(2016 May)
Kalyani R,Lee JY,Min H,Yoon H,Kim MH

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Ptpn13 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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