Gene Symbol | Ptgs1 |
Entrez Gene ID | 19224 |
Full Name | prostaglandin-endoperoxide synthase 1 |
Synonyms | COX1,Cox-1,Cox-3,PGHS-1,PHS 1,Pghs1 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome | |
Summary | This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. [provided by RefSeq, Jan 2014]. |