Ppp2cb cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ppp2cb
Entrez Gene ID	19053
Full Name	protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
Synonyms	AI115466,D8Ertd766e,PP2Ac
General protein information	Preferred Names protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform Names serine/threonine-protein phosphatase 2A catalytic subunit beta isoform PP2A-beta protein phosphatase 2a, catalytic subunit, beta isoform
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8 A3\|8 20.63 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006509033.2	XP_006509096.1	serine/threonine-protein phosphatase 2A catalytic subunit beta isoform isoform X1
NM_017374.3	NP_059070.1	serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
XM_006509033.1	XP_006509096.1	serine/threonine-protein phosphatase 2A catalytic subunit beta isoform isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	PPP2CB	NP_001009552.1
Pan troglodytes (chimpanzee)	PPP2CB	XP_519697.2
	PPP2CB	XP_001084560.1
Danio rerio (zebrafish)	ppp2cb	NP_998458.1
Saccharomyces cerevisiae (baker's yeast)	PPH22	NP_010093.1
Magnaporthe oryzae (rice blast fungus)	MGG_06099	XP_003711965.1
Oryza sativa (rice)	Os10g0410600	NP_001064578.1
Xenopus tropicalis (tropical clawed frog)	ppp2cb	NP_001005443.1
Saccharomyces cerevisiae (baker's yeast)	PPH21	NP_010147.1
Neurospora crassa	NCU06630	XP_961818.2
Canis lupus familiaris (dog)	PPP2CB	XP_539988.1
Mus musculus (house mouse)	Ppp2cb	NP_059070.1
Schizosaccharomyces pombe (fission yeast)	ppa2	NP_595940.1
Gallus gallus (chicken)	PPP2CB	NP_990455.1
Eremothecium gossypii	AGOS_ADR099C	NP_984195.1
Oryza sativa (rice)	Os03g0167700	NP_001049084.1
Bos taurus (cattle)	PPP2CB	NP_001069325.1
Rattus norvegicus (Norway rat)	Ppp2cb	NP_058736.1
Kluyveromyces lactis	KLLA0F05357g	XP_455323.1

Gene Ontology
Bibliography

Related articles in PubMed

PP2A Inactivation Mediated by
Sents W, Meeusen B, Kalev P, Radaelli E, Sagaert X, Miermans E, Haesen D, Lambrecht C, Dewerchin M, Carmeliet P, Westermarck J, Sablina A, Janssens V
Cancer research77(24)6825-6837(2017 Dec)

Do Gametes Woo? Evidence for Their Nonrandom Union at Fertilization.
Nadeau JH
Genetics207(2)369-387(2017 Oct)

Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy.
Zhou T, Li J, Zhao P, Liu H, Jia D, Jia H, He L, Cang Y, Boast S, Chen YH, Thibault H, Scherrer-Crosbie M, Goff SP, Li B
Proceedings of the National Academy of Sciences of the United States of America112(51)15666-71(2015 Dec)

The ? isoform of the catalytic subunit of protein phosphatase 2B restrains platelet function by suppressing outside-in ?II b ?3 integrin signaling.
Khatlani T, Pradhan S, Da Q, Gushiken FC, Bergeron AL, Langlois KW, Molkentin JD, Rumbaut RE, Vijayan KV
Journal of thrombosis and haemostasis : JTH12(12)2089-101(2014 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PP2B-Abeta limits platelet response to vascular injury by suppressing outside-in alphaII b beta3 integrin signaling
Title: The ? isoform of the catalytic subunit of protein phosphatase 2B restrains platelet function by suppressing outside-in ?II b ?3 integrin signaling.

TRPV1 activation in endothelial cells may elicit a Ca(2+) -dependent effect on PP2B-PKC signalling, which leads to dephosphorylation of eNOS
Title: Activation of transient receptor potential vanilloid 1 decreases endothelial nitric oxide synthase phosphorylation at Thr497 by protein phosphatase 2B-dependent dephosphorylation of protein kinase C.

PP2A activation via rapid, non-nuclear ER signaling may be a novel target for therapeutic approaches to inhibit vascular smooth muscle proliferation, which plays a central role in atherosclerosis and restenosis.
Title: Rapid estrogen receptor signaling mediates estrogen-induced inhibition of vascular smooth muscle cell proliferation.

This study provides evidence that CaBP4 is dephosphorylated by PP2A in the retina.
Title: Protein phosphatase 2A dephosphorylates CaBP4 and regulates CaBP4 function.

generated conditional null alleles of Ppp2ca and Ppp2cb by flanking with loxP sites exons 3 to 5 of Ppp2ca and exon 3 of Ppp2cb. Ppp2ca(fl/fl) mice did not display any visible phenotype
Title: Generation of Ppp2Ca and Ppp2Cb conditional null alleles in mouse.

The following Ppp2cb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ppp2cb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu22198	NM_017374.3 Latest version!	Mus musculus protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (Ppp2cb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu40576	XM_006509033.2 Latest version!	Mus musculus protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (Ppp2cb), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu40576	XM_006509033.1	Mus musculus protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (Ppp2cb), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ppp2cb ( NM_017374.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_059070.1 Mus musculus protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (Ppp2cb), mRNA.

Price & Availability↑

CloneID	OMu22198
Clone ID Related Accession (Same CDS sequence)	NM_017374.3
Accession Version	NM_017374.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 930bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CK619614.1, AK090311.1, BE847789.1 and AA220297.1. On Dec 20, 2006 this sequence version replaced NM_017374.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC058582.1, AK090311.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGACGACA AGGCGTTCAC CAAGGAGCTG GACCAGTGGG TGGAGCAGCT GAACGAGTGT 
AAGCAGCTGA ACGAGAACCA AGTGCGGACG CTGTGCGAGA AGGCTAAGGA AATTTTAACG 
AAAGAATCAA ATGTGCAAGA GGTCCGCTGT CCTGTTACCG TCTGTGGAGA TGTGCATGGC 
CAATTCCATG ACCTTATGGA GCTCTTCAGA ATTGGTGGGA AATCACCAGA TACGAACTAC 
CTATTCATGG GGGACTATGT AGACAGAGGG TACTACTCTG TGGAGACTGT GACTCTTCTT 
GTAGCATTAA AGGTGCGCTA TCCAGAGCGC ATCACAATAT TGCGAGGAAA TCACGAAAGC 
CGGCAGATCA CACAAGTGTA TGGCTTTTAT GATGAGTGCC TACGGAAGTA TGGAAATGCC 
AACGTGTGGA AATACTTTAC AGATCTCTTT GATTATCTTC CACTTACAGC TTTAGTAGAT 
GGACAGATAT TCTGCCTCCA CGGTGGCCTG TCTCCATCCA TAGATACACT GGACCACATA 
AGAGCCCTGG ATCGCTTGCA AGAAGTTCCA CATGAGGGCC CAATGTGTGA TCTCTTATGG 
TCAGATCCGG ATGACCGTGG CGGCTGGGGC ATTTCTCCAC GTGGTGCTGG CTACACATTT 
GGACAAGACA TTTCTGAAAC ATTTAACCAT GCCAACGGTC TCACACTGGT GTCTCGTGCT 
CACCAGCTTG TAATGGAAGG ATATAACTGG TGCCATGATC GGAATGTGGT CACCATTTTT 
AGTGCGCCCA ATTACTGCTA CCGTTGTGGG AACCAGGCTG CTATCATGGA ATTAGATGAC 
ACTTTAAAAT ATTCATTTCT TCAGTTTGAC CCAGCACCTC GTCGTGGAGA GCCTCATGTG 
ACCCGGCGCA CCCCAGACTA CTTCCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_059070.1
CDS	297..1226
Translation	MDDKAFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL

Target ORF information:

RefSeq Version	NM_017374.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (Ppp2cb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017374.3

ORF Insert Sequence:

ATGGACGACA AGGCGTTCAC CAAGGAGCTG GACCAGTGGG TGGAGCAGCT GAACGAGTGT 
AAGCAGCTGA ACGAGAACCA AGTGCGGACG CTGTGCGAGA AGGCTAAGGA AATTTTAACG 
AAAGAATCAA ATGTGCAAGA GGTCCGCTGT CCTGTTACCG TCTGTGGAGA TGTGCATGGC 
CAATTCCATG ACCTTATGGA GCTCTTCAGA ATTGGTGGGA AATCACCAGA TACGAACTAC 
CTATTCATGG GGGACTATGT AGACAGAGGG TACTACTCTG TGGAGACTGT GACTCTTCTT 
GTAGCATTAA AGGTGCGCTA TCCAGAGCGC ATCACAATAT TGCGAGGAAA TCACGAAAGC 
CGGCAGATCA CACAAGTGTA TGGCTTTTAT GATGAGTGCC TACGGAAGTA TGGAAATGCC 
AACGTGTGGA AATACTTTAC AGATCTCTTT GATTATCTTC CACTTACAGC TTTAGTAGAT 
GGACAGATAT TCTGCCTCCA CGGTGGCCTG TCTCCATCCA TAGATACACT GGACCACATA 
AGAGCCCTGG ATCGCTTGCA AGAAGTTCCA CATGAGGGCC CAATGTGTGA TCTCTTATGG 
TCAGATCCGG ATGACCGTGG CGGCTGGGGC ATTTCTCCAC GTGGTGCTGG CTACACATTT 
GGACAAGACA TTTCTGAAAC ATTTAACCAT GCCAACGGTC TCACACTGGT GTCTCGTGCT 
CACCAGCTTG TAATGGAAGG ATATAACTGG TGCCATGATC GGAATGTGGT CACCATTTTT 
AGTGCGCCCA ATTACTGCTA CCGTTGTGGG AACCAGGCTG CTATCATGGA ATTAGATGAC 
ACTTTAAAAT ATTCATTTCT TCAGTTTGAC CCAGCACCTC GTCGTGGAGA GCCTCATGTG 
ACCCGGCGCA CCCCAGACTA CTTCCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ppp2cb ( XM_006509033.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006509096.1 Mus musculus protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (Ppp2cb), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu40576
Clone ID Related Accession (Same CDS sequence)	XM_006509033.2 , XM_006509033.1
Accession Version	XM_006509033.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein phosphatase 2A catalytic subunit beta isoform isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTCT TCAGAATTGG TGGGAAATCA CCAGATACGA ACTACCTATT CATGGGGGAC 
TATGTAGACA GAGGGTACTA CTCTGTGGAG ACTGTGACTC TTCTTGTAGC ATTAAAGGTG 
CGCTATCCAG AGCGCATCAC AATATTGCGA GGAAATCACG AAAGCCGGCA GATCACACAA 
GTGTATGGCT TTTATGATGA GTGCCTACGG AAGTATGGAA ATGCCAACGT GTGGAAATAC 
TTTACAGATC TCTTTGATTA TCTTCCACTT ACAGCTTTAG TAGATGGACA GATATTCTGC 
CTCCACGGTG GCCTGTCTCC ATCCATAGAT ACACTGGACC ACATAAGAGC CCTGGATCGC 
TTGCAAGAAG TTCCACATGA GGGCCCAATG TGTGATCTCT TATGGTCAGA TCCGGATGAC 
CGTGGCGGCT GGGGCATTTC TCCACGTGGT GCTGGCTACA CATTTGGACA AGACATTTCT 
GAAACATTTA ACCATGCCAA CGGTCTCACA CTGGTGTCTC GTGCTCACCA GCTTGTAATG 
GAAGGATATA ACTGGTGCCA TGATCGGAAT GTGGTCACCA TTTTTAGTGC GCCCAATTAC 
TGCTACCGTT GTGGGAACCA GGCTGCTATC ATGGAATTAG ATGACACTTT AAAATATTCA 
TTTCTTCAGT TTGACCCAGC ACCTCGTCGT GGAGAGCCTC ATGTGACCCG GCGCACCCCA 
GACTACTTCC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006509096.1
CDS	277..1011
Translation	MELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL

Target ORF information:

RefSeq Version	XM_006509033.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (Ppp2cb), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006509033.1

ORF Insert Sequence:

ATGGAGCTCT TCAGAATTGG TGGGAAATCA CCAGATACGA ACTACCTATT CATGGGGGAC 
TATGTAGACA GAGGGTACTA CTCTGTGGAG ACTGTGACTC TTCTTGTAGC ATTAAAGGTG 
CGCTATCCAG AGCGCATCAC AATATTGCGA GGAAATCACG AAAGCCGGCA GATCACACAA 
GTGTATGGCT TTTATGATGA GTGCCTACGG AAGTATGGAA ATGCCAACGT GTGGAAATAC 
TTTACAGATC TCTTTGATTA TCTTCCACTT ACAGCTTTAG TAGATGGACA GATATTCTGC 
CTCCACGGTG GCCTGTCTCC ATCCATAGAT ACACTGGACC ACATAAGAGC CCTGGATCGC 
TTGCAAGAAG TTCCACATGA GGGCCCAATG TGTGATCTCT TATGGTCAGA TCCGGATGAC 
CGTGGCGGCT GGGGCATTTC TCCACGTGGT GCTGGCTACA CATTTGGACA AGACATTTCT 
GAAACATTTA ACCATGCCAA CGGTCTCACA CTGGTGTCTC GTGCTCACCA GCTTGTAATG 
GAAGGATATA ACTGGTGCCA TGATCGGAAT GTGGTCACCA TTTTTAGTGC GCCCAATTAC 
TGCTACCGTT GTGGGAACCA GGCTGCTATC ATGGAATTAG ATGACACTTT AAAATATTCA 
TTTCTTCAGT TTGACCCAGC ACCTCGTCGT GGAGAGCCTC ATGTGACCCG GCGCACCCCA 
GACTACTTCC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ppp2cb ( XM_006509033.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006509096.1 Mus musculus protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (Ppp2cb), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu40576
Clone ID Related Accession (Same CDS sequence)	XM_006509033.2 , XM_006509033.1
Accession Version	XM_006509033.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein phosphatase 2A catalytic subunit beta isoform isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006509033.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTCT TCAGAATTGG TGGGAAATCA CCAGATACGA ACTACCTATT CATGGGGGAC 
TATGTAGACA GAGGGTACTA CTCTGTGGAG ACTGTGACTC TTCTTGTAGC ATTAAAGGTG 
CGCTATCCAG AGCGCATCAC AATATTGCGA GGAAATCACG AAAGCCGGCA GATCACACAA 
GTGTATGGCT TTTATGATGA GTGCCTACGG AAGTATGGAA ATGCCAACGT GTGGAAATAC 
TTTACAGATC TCTTTGATTA TCTTCCACTT ACAGCTTTAG TAGATGGACA GATATTCTGC 
CTCCACGGTG GCCTGTCTCC ATCCATAGAT ACACTGGACC ACATAAGAGC CCTGGATCGC 
TTGCAAGAAG TTCCACATGA GGGCCCAATG TGTGATCTCT TATGGTCAGA TCCGGATGAC 
CGTGGCGGCT GGGGCATTTC TCCACGTGGT GCTGGCTACA CATTTGGACA AGACATTTCT 
GAAACATTTA ACCATGCCAA CGGTCTCACA CTGGTGTCTC GTGCTCACCA GCTTGTAATG 
GAAGGATATA ACTGGTGCCA TGATCGGAAT GTGGTCACCA TTTTTAGTGC GCCCAATTAC 
TGCTACCGTT GTGGGAACCA GGCTGCTATC ATGGAATTAG ATGACACTTT AAAATATTCA 
TTTCTTCAGT TTGACCCAGC ACCTCGTCGT GGAGAGCCTC ATGTGACCCG GCGCACCCCA 
GACTACTTCC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006509096.1
CDS	302..1036
Translation	MELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL

Target ORF information:

RefSeq Version	XM_006509033.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (Ppp2cb), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006509033.2

ORF Insert Sequence:

ATGGAGCTCT TCAGAATTGG TGGGAAATCA CCAGATACGA ACTACCTATT CATGGGGGAC 
TATGTAGACA GAGGGTACTA CTCTGTGGAG ACTGTGACTC TTCTTGTAGC ATTAAAGGTG 
CGCTATCCAG AGCGCATCAC AATATTGCGA GGAAATCACG AAAGCCGGCA GATCACACAA 
GTGTATGGCT TTTATGATGA GTGCCTACGG AAGTATGGAA ATGCCAACGT GTGGAAATAC 
TTTACAGATC TCTTTGATTA TCTTCCACTT ACAGCTTTAG TAGATGGACA GATATTCTGC 
CTCCACGGTG GCCTGTCTCC ATCCATAGAT ACACTGGACC ACATAAGAGC CCTGGATCGC 
TTGCAAGAAG TTCCACATGA GGGCCCAATG TGTGATCTCT TATGGTCAGA TCCGGATGAC 
CGTGGCGGCT GGGGCATTTC TCCACGTGGT GCTGGCTACA CATTTGGACA AGACATTTCT 
GAAACATTTA ACCATGCCAA CGGTCTCACA CTGGTGTCTC GTGCTCACCA GCTTGTAATG 
GAAGGATATA ACTGGTGCCA TGATCGGAAT GTGGTCACCA TTTTTAGTGC GCCCAATTAC 
TGCTACCGTT GTGGGAACCA GGCTGCTATC ATGGAATTAG ATGACACTTT AAAATATTCA 
TTTCTTCAGT TTGACCCAGC ACCTCGTCGT GGAGAGCCTC ATGTGACCCG GCGCACCCCA 
GACTACTTCC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PP2A Inactivation Mediated by
Cancer research77(24)6825-6837(2017 Dec)
Sents W,Meeusen B,Kalev P,Radaelli E,Sagaert X,Miermans E,Haesen D,Lambrecht C,Dewerchin M,Carmeliet P,Westermarck J,Sablina A,Janssens V

Do Gametes Woo? Evidence for Their Nonrandom Union at Fertilization.
Genetics207(2)369-387(2017 Oct)
Nadeau JH

Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy.
Proceedings of the National Academy of Sciences of the United States of America112(51)15666-71(2015 Dec)
Zhou T,Li J,Zhao P,Liu H,Jia D,Jia H,He L,Cang Y,Boast S,Chen YH,Thibault H,Scherrer-Crosbie M,Goff SP,Li B

The ? isoform of the catalytic subunit of protein phosphatase 2B restrains platelet function by suppressing outside-in ?II b ?3 integrin signaling.
Journal of thrombosis and haemostasis : JTH12(12)2089-101(2014 Dec)
Khatlani T,Pradhan S,Da Q,Gushiken FC,Bergeron AL,Langlois KW,Molkentin JD,Rumbaut RE,Vijayan KV

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Ppp2cb cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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