Bpifa1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Bpifa1
Entrez Gene ID	18843
Full Name	BPI fold containing family A, member 1
Synonyms	LUNX,NASG,Plunc,SPLUNC1,SPURT
General protein information	Preferred Names BPI fold containing family A, member 1 Names BPI fold-containing family A member 1 palate lung and nasal epithelium clone protein palate, lung, and nasal epithelium associated palate, lung, and nasal epithelium clone palate, lung, and nasal epithelium expressed transcript protein Plunc
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 H1

mRNA and Protein(s)

mRNA	Protein	Name
NM_011126.3	NP_035256.2	BPI fold-containing family A member 1 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Bpifa1	NP_742028.1
Canis lupus familiaris (dog)	BPIFA1	XP_852441.1
Homo sapiens (human)	BPIFA1	NP_001230122.1
Bos taurus (cattle)	BPIFA1	NP_776851.1
Mus musculus (house mouse)	Bpifa1	NP_035256.2
Pan troglodytes (chimpanzee)	BPIFA1	XP_514582.2
	BPIFA1	XP_001104307.2

Gene Ontology
Bibliography

Related articles in PubMed

An innate defense peptide BPIFA1/SPLUNC1 restricts influenza A virus infection.
Akram KM, Moyo NA, Leeming GH, Bingle L, Jasim S, Hussain S, Schorlemmer A, Kipar A, Digard P, Tripp RA, Shohet RV, Bingle CD, Stewart JP
Mucosal immunology11(1)71-81(2018 Jan)

SPLUNC1 knockout enhances LPS-induced lung injury by increasing recruitment of CD11b+Gr-1+ cells to the spleen of mice.
Zhang H, Li X, Liao S, Wang H, Chen P, Zhu G, Luo Y, Li G, Zhou Y
Oncology reports39(1)358-366(2018 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Loss of Splunc1 predisposes mice to the development of otitis media.
Title: Increased susceptibility to otitis media in a Splunc1-deficient mouse model.

SPLUNC1 is present at high concentrations in murine airways under basal conditions, whereas it is suppressed by low-level environmental pathogen-associated molecular patterns and inflammatory signals.
Title: Short palate, lung, and nasal epithelial clone-1 is a tightly regulated airway sensor in innate and adaptive immunity.

SPLUNC1 is a crucial component of mucosal innate immune defense against pulmonary infection.
Title: SPLUNC1/BPIFA1 contributes to pulmonary host defense against Klebsiella pneumoniae respiratory infection.

Knowledge of the complex expression patterns of BPIF proteins in these regions will allow the use of tractable mouse models of disease to dissect their function.
Title: Differential localisation of BPIFA1 (SPLUNC1) and BPIFB1 (LPLUNC1) in the nasal and oral cavities of mice.

SPLUNC1 KO mice demonstrated significantly higher numbers of eosinophils in the lung after OVA challenges than did wild-type mice.
Title: SPLUNC1 deficiency enhances airway eosinophilic inflammation in mice.

The following Bpifa1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bpifa1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu20056	NM_011126.3 Latest version!	Mus musculus BPI fold containing family A, member 1 (Bpifa1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Bpifa1 ( NM_011126.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035256.2 Mus musculus BPI fold containing family A, member 1 (Bpifa1), mRNA.

Price & Availability↑

CloneID	OMu20056
Clone ID Related Accession (Same CDS sequence)	NM_011126.3
Accession Version	NM_011126.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 837bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	BPI fold-containing family A member 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY121014.1 and BC054375.1. On Apr 28, 2009 this sequence version replaced NM_011126.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U69172.1, BC054375.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383, SAMN00849387 [ECO:0000348] ##Evidence-Data-END##

ATGTTTCTAG TTGGGAGCCT CGTTGTCCTC TGTGGGCTGC TGGCCCACAG CACAGCACAG 
CTGGCAGGCT TGCCATTGCC CCTGGGCCAG GGTCCACCCT TGCCACTGAA CCAGGGCCCA 
CCGTTGCCAC TGAACCAGGG CCAGCTGTTG CCCCTGGCTC AGGGTCTGCC TTTGGCTGTA 
AGCCCAGCAC TGCCTTCAAA TCCCACAGAT CTTCTTGCTG GAAAATTCAC AGATGCTCTC 
AGCGGTGGCC TGCTGTCTGG GGGGCTGCTG GGCATTTTGG AAAATATTCC ACTCCTGGAT 
GTTATAAAGT CTGGAGGAGG CAATTCTAAT GGCCTTGTTG GGGGCCTGCT GGGAAAACTG 
ACGTCATCAG TTCCTCTCCT GAACAACATC CTCGACATAA AAATCACTGA TCCGCAGCTG 
CTAGAACTTG GTCTTGTGCA GAGTCCTGAT GGCCATCGTC TCTATGTCAC CATCCCTCTG 
GGCTTGACAC TCAACGTAAA TATGCCCGTA GTTGGAAGTC TTTTGCAATT GGCTGTGAAG 
CTGAACATTA CTGCAGAAGT CTTAGCCGTG AAAGACAATC AGGGGAGGAT TCATCTGGTT 
CTTGGTGACT GCACCCACTC CCCTGGCAGC CTGAAAATCA GCTTGCTCAA TGGAGTCACT 
CCTGTTCAAA GCTTTTTAGA CAACCTCACA GGGATATTGA CTAAAGTCCT TCCTGAGCTG 
ATCCAGGGCA AGGTATGTCC TCTGGTCAAT GGGATTCTCA GCGGTTTGGA TGTCACCCTG 
GTGCACAACA TTGCTGAATT ACTGATCCAT GGACTACAGT TTGTCATCAA AGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035256.2
CDS	60..896
Translation	MFLVGSLVVLCGLLAHSTAQLAGLPLPLGQGPPLPLNQGPPLPLNQGQLLPLAQGLPLAVSPALPSNPTDLLAGKFTDALSGGLLSGGLLGILENIPLLDVIKSGGGNSNGLVGGLLGKLTSSVPLLNNILDIKITDPQLLELGLVQSPDGHRLYVTIPLGLTLNVNMPVVGSLLQLAVKLNITAEVLAVKDNQGRIHLVLGDCTHSPGSLKISLLNGVTPVQSFLDNLTGILTKVLPELIQGKVCPLVNGILSGLDVTLVHNIAELLIHGLQFVIKV

Target ORF information:

RefSeq Version	NM_011126.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus BPI fold containing family A, member 1 (Bpifa1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011126.3

ORF Insert Sequence:

ATGTTTCTAG TTGGGAGCCT CGTTGTCCTC TGTGGGCTGC TGGCCCACAG CACAGCACAG 
CTGGCAGGCT TGCCATTGCC CCTGGGCCAG GGTCCACCCT TGCCACTGAA CCAGGGCCCA 
CCGTTGCCAC TGAACCAGGG CCAGCTGTTG CCCCTGGCTC AGGGTCTGCC TTTGGCTGTA 
AGCCCAGCAC TGCCTTCAAA TCCCACAGAT CTTCTTGCTG GAAAATTCAC AGATGCTCTC 
AGCGGTGGCC TGCTGTCTGG GGGGCTGCTG GGCATTTTGG AAAATATTCC ACTCCTGGAT 
GTTATAAAGT CTGGAGGAGG CAATTCTAAT GGCCTTGTTG GGGGCCTGCT GGGAAAACTG 
ACGTCATCAG TTCCTCTCCT GAACAACATC CTCGACATAA AAATCACTGA TCCGCAGCTG 
CTAGAACTTG GTCTTGTGCA GAGTCCTGAT GGCCATCGTC TCTATGTCAC CATCCCTCTG 
GGCTTGACAC TCAACGTAAA TATGCCCGTA GTTGGAAGTC TTTTGCAATT GGCTGTGAAG 
CTGAACATTA CTGCAGAAGT CTTAGCCGTG AAAGACAATC AGGGGAGGAT TCATCTGGTT 
CTTGGTGACT GCACCCACTC CCCTGGCAGC CTGAAAATCA GCTTGCTCAA TGGAGTCACT 
CCTGTTCAAA GCTTTTTAGA CAACCTCACA GGGATATTGA CTAAAGTCCT TCCTGAGCTG 
ATCCAGGGCA AGGTATGTCC TCTGGTCAAT GGGATTCTCA GCGGTTTGGA TGTCACCCTG 
GTGCACAACA TTGCTGAATT ACTGATCCAT GGACTACAGT TTGTCATCAA AGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

An innate defense peptide BPIFA1/SPLUNC1 restricts influenza A virus infection.
Mucosal immunology11(1)71-81(2018 Jan)
Akram KM,Moyo NA,Leeming GH,Bingle L,Jasim S,Hussain S,Schorlemmer A,Kipar A,Digard P,Tripp RA,Shohet RV,Bingle CD,Stewart JP

SPLUNC1 knockout enhances LPS-induced lung injury by increasing recruitment of CD11b+Gr-1+ cells to the spleen of mice.
Oncology reports39(1)358-366(2018 Jan)
Zhang H,Li X,Liao S,Wang H,Chen P,Zhu G,Luo Y,Li G,Zhou Y

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Bpifa1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報