Cfp cDNA ORF clone, Mus musculus(house mouse)

Properdin deficiency protects from 5-fluorouracil-induced small intestinal mucositis in a complement activation-independent, interleukin-10-dependent mechanism.
Jain U, Midgen CA, Woodruff TM, Schwaeble WJ, Stover CM, Stadnyk AW
Clinical and experimental immunology188(1)36-44(2017 Apr)

The Complement Regulatory Protein CD46 Deficient Mouse Spontaneously Develops Dry-Type Age-Related Macular Degeneration-Like Phenotype.
Lyzogubov VV, Bora PS, Wu X, Horn LE, de Roque R, Rudolf XV, Atkinson JP, Bora NS
The American journal of pathology186(8)2088-2104(2016 Aug)

Properdin deficiency protects from 5-fluorouracil-induced small intestinal mucositis in a complement activation-independent, interleukin-10-dependent mechanism
Title: Properdin deficiency protects from 5-fluorouracil-induced small intestinal mucositis in a complement activation-independent, interleukin-10-dependent mechanism.

We induced anti-myeloperoxidase vasculitis in mice and showed that neither MASP-2- nor properdin-deficient mice were protected, suggesting that alternative pathway activation does not require properdin or the lectin pathway.
Title: Experimentally-induced anti-myeloperoxidase vasculitis does not require properdin, MASP-2 or bone marrow-derived C5.

The results show that Properdin plays a key role in allergen-induced airway inflammation and represents a potential therapeutic target for human asthma.
Title: Properdin Contributes to Allergic Airway Inflammation through Local C3a Generation.

Authors conclude that properdin controls the strength of immune responses by affecting humoral as well as cellular phenotypes during acute bacterial infection and ensuing inflammation.
Title: Septicaemia models using Streptococcus pneumoniae and Listeria monocytogenes: understanding the role of complement properdin.

deficiency of properdin in mice with factor H mutation exacerbates C3 glomerulonephritis
Title: Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.