Padi2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Padi2
Entrez Gene ID	18600
Full Name	peptidyl arginine deiminase, type II
Synonyms	Pdi,Pdi2,mKIAA0994
General protein information	Preferred Names peptidyl arginine deiminase, type II Names protein-arginine deiminase type-2 PAD type II peptidyl arginine deiminase, type II; PAD type II peptidylarginine deiminase II protein-arginine deiminase type II
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4 D3\|4 73.01 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008812.2	NP_032838.2	protein-arginine deiminase type-2
XM_006538632.4	XP_006538695.1	protein-arginine deiminase type-2 isoform X1
XM_006538632.3	XP_006538695.1	protein-arginine deiminase type-2 isoform X1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	padi2	NP_956406.1
Xenopus tropicalis (tropical clawed frog)	padi2	NP_001096490.1
Homo sapiens (human)	PADI2	NP_031391.2
Canis lupus familiaris (dog)	PADI2	XP_544539.2
Mus musculus (house mouse)	Padi2	NP_032838.2
Pan troglodytes (chimpanzee)	PADI2	XP_513113.3
	PADI2	XP_001099772.2
Gallus gallus (chicken)	PADI2	XP_425730.3
Rattus norvegicus (Norway rat)	Padi2	NP_058922.1

Gene Ontology
Bibliography

Related articles in PubMed

Peptidylarginine deiminase 2 is required for tumor necrosis factor alpha-induced citrullination and arthritis, but not neutrophil extracellular trap formation.
Bawadekar M, Shim D, Johnson CJ, Warner TF, Rebernick R, Damgaard D, Nielsen CH, Pruijn GJM, Nett JE, Shelef MA
Journal of autoimmunity8039-47(2017 Jun)

Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice.
Khajavi M, Zhou Y, Birsner AE, Bazinet L, Rosa Di Sant A, Schiffer AJ, Rogers MS, Krishnaji ST, Hu B, Nguyen V, Zon L, D'Amato RJ
PLoS genetics13(6)e1006848(2017 Jun)

Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development.
Zhang X, Liu X, Zhang M, Li T, Muth A, Thompson PR, Coonrod SA, Zhang X
Scientific reports638727(2016 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Taken together, our study is the first to indicate the potential role of Padi2 as an angiogenesis-regulating gene. The characterization of Padi2 and other genes in associated pathways may provide new understanding of angiogenesis regulation and novel targets for diagnosis and treatment of a wide variety of angiogenesis-dependent diseases.
Title: Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice.

GPx7 is an unusual CysGPx catalyzing the peroxidatic cycle by a one Cys mechanism in which GSH and PDI are alternative substrates.
Title: Protein disulfide isomerase and glutathione are alternative substrates in the one Cys catalytic cycle of glutathione peroxidase 7.

peptidyl-arginine deiminases inhibiion reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis.
Title: Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis.

Results suggest that PADI2 may function as an important new biomarker for HER2/ERBB2+ tumors and that Cl-amidine represents a new candidate for breast cancer therapy.
Title: Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

Activation of the P2X7 purinergic receptor (P2X7) by the inflammatory danger signal ATP induces PAD2 activity and robust protein citrullination in mast cells.
Title: ATP induces protein arginine deiminase 2-dependent citrullination in mast cells through the P2X7 purinergic receptor.

The following Padi2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Padi2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu21436	NM_008812.2 Latest version!	Mus musculus peptidyl arginine deiminase, type II (Padi2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu34045	XM_006538632.4 Latest version!	Mus musculus peptidyl arginine deiminase, type II (Padi2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OMu34045	XM_006538632.3	Mus musculus peptidyl arginine deiminase, type II (Padi2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Padi2 ( NM_008812.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032838.2 Mus musculus peptidyl arginine deiminase, type II (Padi2), mRNA.

Price & Availability↑

CloneID	OMu21436
Clone ID Related Accession (Same CDS sequence)	NM_008812.2
Accession Version	NM_008812.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2022bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-07
Organism	Mus musculus(house mouse)
Product	protein-arginine deiminase type-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB850871.1, AK148156.1, AK158382.1, AK168685.1 and AL645625.15. On Apr 2, 2008 this sequence version replaced NM_008812.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D16580.1, AK154814.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCAGCCGC CTATACGGGA AAATATGCTG CGGGAACGGA CCGTGCGGCT GCAGTATGGG 
AGCCGCGTGG AGGCGGTGTA CGTGCTGGGC ACGCAGCTCT GGACCGATGT CTACAGTGCA 
GCACCTGCTG GGGCCAAAAC CTTCAGCCTG AAGCACTCGG AAGGTGTGAA GGTGGAGGTC 
GTACGTGATG GAGAGGCAGA GGAGGTGGTC ACCAACGGCA AGCAGCGCTG GGCCCTGTCA 
CCCAGCAGCA CACTGCGGCT CAGCATGGCC CAGGCCAGCA CAGAGGCCAG CAGCGACAAG 
GTCACTGTCA ACTACTATGA AGAGGAGGGC AGCGCCCCCA TTGACCAGGC TGGGCTCTTC 
CTCACGGCCA TTGAGATCTC GCTGGATGTG GACGCAGATC GGGATGGAGA GGTGGAGAAG 
AACAATCCTA AGAAGGCATC CTGGACCTGG GGTCCTGAGG GCCAAGGGGC TATCCTGCTG 
GTGAATTGTG ACCGAGACAC ACCCTGGTTG CCCAAGGAGG ACTGTAGTGA CGAAAAGGTC 
TACAGCAAGC AAGACCTCCA GGACATGTCT CAGATGATCC TGCGCACCAA AGGCCCTGAC 
CGCCTGCCCG CCGGGTATGA AATAGTCCTC TACATCTCCA TGTCAGACTC GGACAAAGTG 
GGCGTCTTCT ACGTGGAGAA CCCGTTCTTT GGCCAGCGCT ATATCCACAT CCTGGGCCGG 
CAGAAGCTCT ACCACGTGGT CAAGTACACC GGCGGTTCTG CGGAGTTGCT GTTCTTTGTG 
GAAGGCCTCT GTTTCCCCGA CGAGAGTTTC TCAGGCCTGG TTTCTATCCA CGTCAGTCTG 
CTGGAGTATA TGGCCGAGGG CATCCCGTTG ACCCCCATCT TCACAGACAC TGTGATGTTC 
CGGATTGCAC CCTGGATTAT GACCCCCAAC ATCTTGCCTC CTGTGTCAGT GTTCGTGTGC 
TGCATGAAGG ATAATTACCT GTTCCTGAAA GAGGTGAAGA ACTTGGTGGA GAAAACCAAC 
TGCGAACTGA AAGTTTGTTT CCAGTACATG AACCGCGGTG ACCGCTGGAT CCAGGATGAA 
ATCGAGTTTG GCTACATTGA GGCACCCCAC AAAGGCTTCC CAGTAGTGCT GGACTCCCCT 
CGAGATGGAA ACCTGAAGGA CTTCCCCATT AAGCAACTCC TGGGCCCAGA TTTCGGCTAT 
GTGACCCGGG AGCCCCTCTT TGAGACTGTC ACCAGCCTCG ACTCCTTCGG GAATCTGGAG 
GTCAGTCCCC CAGTGACCGT GAATGGCAAG GAGTACCCGC TTGGCCGGAT CCTCATCGGA 
AGCAGTTTCC CCCTGTCTGG AGGCAGGAGG ATGACCAAGG TGGTACGCGA CTTCCTGCAG 
GCCCAGCAGG TGCAGGCGCC CGTGGAACTC TACTCCGACT GGCTGACTGT AGGCCACGTC 
GATGAGTTTA TGACTTTCAT CCCCATCCCA GGCAAAAAGG AATTTCGGCT GCTCATGGCC 
AGCACCTCCG CCTGCTACCA GCTCTTCCGA GAAAAGCAGA AGGCAGGCCA CGGGGAGGCC 
GTTATGTTCA AGGGCCTGGG AGGCATGAGC AGCAAGCGCA TCACCATCAA CAAGATCCTG 
TCCAATGAGA GCCTCACGCA GGAGAACCAG TACTTCCAGC GCTGTCTGGA CTGGAACCGC 
GACATCCTTA AGAGGGAGCT AGCGCTGACT GAGAAGGACA TTATTGACCT GCCCGCGCTC 
TTCAAGATGG ATGAAAATCA CCAGGCCAGG GCTTTCTTCC CTAACATGGT GAACATGATC 
GTGCTAGACA AGGACCTGGG CATCCCCAAG CCTTTCGGGC CCCAGGTGGA GGAGGAGTGC 
TGCCTGGAGA CGCACGTTCG AGGCCTGCTG GAGCCCCTGG GCCTCGCCTG CACGTTCATC 
GATGACATCT CCGCCTACCA CAAGTTCCTG GGAGAGGTTC ACTGTGGCAC CAATGTCCGC 
AGGAAGCCGT TCACCTTCAA GTGGTGGCAC ATGGTGCCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032838.2
CDS	75..2096
Translation	MQPPIRENMLRERTVRLQYGSRVEAVYVLGTQLWTDVYSAAPAGAKTFSLKHSEGVKVEVVRDGEAEEVVTNGKQRWALSPSSTLRLSMAQASTEASSDKVTVNYYEEEGSAPIDQAGLFLTAIEISLDVDADRDGEVEKNNPKKASWTWGPEGQGAILLVNCDRDTPWLPKEDCSDEKVYSKQDLQDMSQMILRTKGPDRLPAGYEIVLYISMSDSDKVGVFYVENPFFGQRYIHILGRQKLYHVVKYTGGSAELLFFVEGLCFPDESFSGLVSIHVSLLEYMAEGIPLTPIFTDTVMFRIAPWIMTPNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYMNRGDRWIQDEIEFGYIEAPHKGFPVVLDSPRDGNLKDFPIKQLLGPDFGYVTREPLFETVTSLDSFGNLEVSPPVTVNGKEYPLGRILIGSSFPLSGGRRMTKVVRDFLQAQQVQAPVELYSDWLTVGHVDEFMTFIPIPGKKEFRLLMASTSACYQLFREKQKAGHGEAVMFKGLGGMSSKRITINKILSNESLTQENQYFQRCLDWNRDILKRELALTEKDIIDLPALFKMDENHQARAFFPNMVNMIVLDKDLGIPKPFGPQVEEECCLETHVRGLLEPLGLACTFIDDISAYHKFLGEVHCGTNVRRKPFTFKWWHMVP

Target ORF information:

RefSeq Version	NM_008812.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus peptidyl arginine deiminase, type II (Padi2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008812.2

ORF Insert Sequence:

ATGCAGCCGC CTATACGGGA AAATATGCTG CGGGAACGGA CCGTGCGGCT GCAGTATGGG 
AGCCGCGTGG AGGCGGTGTA CGTGCTGGGC ACGCAGCTCT GGACCGATGT CTACAGTGCA 
GCACCTGCTG GGGCCAAAAC CTTCAGCCTG AAGCACTCGG AAGGTGTGAA GGTGGAGGTC 
GTACGTGATG GAGAGGCAGA GGAGGTGGTC ACCAACGGCA AGCAGCGCTG GGCCCTGTCA 
CCCAGCAGCA CACTGCGGCT CAGCATGGCC CAGGCCAGCA CAGAGGCCAG CAGCGACAAG 
GTCACTGTCA ACTACTATGA AGAGGAGGGC AGCGCCCCCA TTGACCAGGC TGGGCTCTTC 
CTCACGGCCA TTGAGATCTC GCTGGATGTG GACGCAGATC GGGATGGAGA GGTGGAGAAG 
AACAATCCTA AGAAGGCATC CTGGACCTGG GGTCCTGAGG GCCAAGGGGC TATCCTGCTG 
GTGAATTGTG ACCGAGACAC ACCCTGGTTG CCCAAGGAGG ACTGTAGTGA CGAAAAGGTC 
TACAGCAAGC AAGACCTCCA GGACATGTCT CAGATGATCC TGCGCACCAA AGGCCCTGAC 
CGCCTGCCCG CCGGGTATGA AATAGTCCTC TACATCTCCA TGTCAGACTC GGACAAAGTG 
GGCGTCTTCT ACGTGGAGAA CCCGTTCTTT GGCCAGCGCT ATATCCACAT CCTGGGCCGG 
CAGAAGCTCT ACCACGTGGT CAAGTACACC GGCGGTTCTG CGGAGTTGCT GTTCTTTGTG 
GAAGGCCTCT GTTTCCCCGA CGAGAGTTTC TCAGGCCTGG TTTCTATCCA CGTCAGTCTG 
CTGGAGTATA TGGCCGAGGG CATCCCGTTG ACCCCCATCT TCACAGACAC TGTGATGTTC 
CGGATTGCAC CCTGGATTAT GACCCCCAAC ATCTTGCCTC CTGTGTCAGT GTTCGTGTGC 
TGCATGAAGG ATAATTACCT GTTCCTGAAA GAGGTGAAGA ACTTGGTGGA GAAAACCAAC 
TGCGAACTGA AAGTTTGTTT CCAGTACATG AACCGCGGTG ACCGCTGGAT CCAGGATGAA 
ATCGAGTTTG GCTACATTGA GGCACCCCAC AAAGGCTTCC CAGTAGTGCT GGACTCCCCT 
CGAGATGGAA ACCTGAAGGA CTTCCCCATT AAGCAACTCC TGGGCCCAGA TTTCGGCTAT 
GTGACCCGGG AGCCCCTCTT TGAGACTGTC ACCAGCCTCG ACTCCTTCGG GAATCTGGAG 
GTCAGTCCCC CAGTGACCGT GAATGGCAAG GAGTACCCGC TTGGCCGGAT CCTCATCGGA 
AGCAGTTTCC CCCTGTCTGG AGGCAGGAGG ATGACCAAGG TGGTACGCGA CTTCCTGCAG 
GCCCAGCAGG TGCAGGCGCC CGTGGAACTC TACTCCGACT GGCTGACTGT AGGCCACGTC 
GATGAGTTTA TGACTTTCAT CCCCATCCCA GGCAAAAAGG AATTTCGGCT GCTCATGGCC 
AGCACCTCCG CCTGCTACCA GCTCTTCCGA GAAAAGCAGA AGGCAGGCCA CGGGGAGGCC 
GTTATGTTCA AGGGCCTGGG AGGCATGAGC AGCAAGCGCA TCACCATCAA CAAGATCCTG 
TCCAATGAGA GCCTCACGCA GGAGAACCAG TACTTCCAGC GCTGTCTGGA CTGGAACCGC 
GACATCCTTA AGAGGGAGCT AGCGCTGACT GAGAAGGACA TTATTGACCT GCCCGCGCTC 
TTCAAGATGG ATGAAAATCA CCAGGCCAGG GCTTTCTTCC CTAACATGGT GAACATGATC 
GTGCTAGACA AGGACCTGGG CATCCCCAAG CCTTTCGGGC CCCAGGTGGA GGAGGAGTGC 
TGCCTGGAGA CGCACGTTCG AGGCCTGCTG GAGCCCCTGG GCCTCGCCTG CACGTTCATC 
GATGACATCT CCGCCTACCA CAAGTTCCTG GGAGAGGTTC ACTGTGGCAC CAATGTCCGC 
AGGAAGCCGT TCACCTTCAA GTGGTGGCAC ATGGTGCCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Padi2 ( XM_006538632.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006538695.1 Mus musculus peptidyl arginine deiminase, type II (Padi2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu34045
Clone ID Related Accession (Same CDS sequence)	XM_006538632.4 , XM_006538632.3
Accession Version	XM_006538632.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2088bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	protein-arginine deiminase type-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006538632.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCCGC CTATACGGGA AAATATGCTG CGGGAACGGA CCGTGCGGCT GCAGTATGGG 
AGCCGCGTGG AGGCGGTGTA CGTGCTGGGC ACGCAGCTCT GGACCGATGT CTACAGTGCA 
GCACCTGCTG GGGCCAAAAC CTTCAGCCTG AAGCACTCGG AAGGTGTGAA GGTGGAGGTC 
GTACGTGATG GAGAGGCAGA GGAGGTGGTC ACCAACGGCA AGCAGCGCTG GGCCCTGTCA 
CCCAGCAGCA CACTGCGGCT CAGCATGGCC CAGGCCAGCA CAGAGGCCAG CAGCGACAAG 
GTCACTGTCA ACTACTATGA AGAGGAGGGC AGCGCCCCCA TTGACCAGGC TGGGCTCTTC 
CTCACGGCCA TTGAGATCTC GCTGGATGTG GACGCAGATC GGGATGGAGA GGTGGAGAAG 
AACAATCCTA AGAAGGCATC CTGGACCTGG GGTCCTGAGG GCCAAGGGGC TATCCTGCTG 
GTGAATTGTG ACCGAGACAC ACCCTGGTTG CCCAAGGAGG ACTGTAGTGA CGAAAAGGTC 
TACAGCAAGC AAGACCTCCA GGACATGTCT CAGATGATCC TGCGCACCAA AGGCCCTGAC 
CGCCTGCCCG CCGGGTATGA AATAGTCCTC TACATCTCCA TGTCAGACTC GGACAAAGTG 
GGCGTCTTCT ACGTGGAGAA TTTGCAGGGC GTAAAGAAGC TGCTTCAGGA ACTCTGTAGG 
GCCCTAGTTC CAGGCCTTTG CCAATACCCG TTCTTTGGCC AGCGCTATAT CCACATCCTG 
GGCCGGCAGA AGCTCTACCA CGTGGTCAAG TACACCGGCG GTTCTGCGGA GTTGCTGTTC 
TTTGTGGAAG GCCTCTGTTT CCCCGACGAG AGTTTCTCAG GCCTGGTTTC TATCCACGTC 
AGTCTGCTGG AGTATATGGC CGAGGGCATC CCGTTGACCC CCATCTTCAC AGACACTGTG 
ATGTTCCGGA TTGCACCCTG GATTATGACC CCCAACATCT TGCCTCCTGT GTCAGTGTTC 
GTGTGCTGCA TGAAGGATAA TTACCTGTTC CTGAAAGAGG TGAAGAACTT GGTGGAGAAA 
ACCAACTGCG AACTGAAAGT TTGTTTCCAG TACATGAACC GCGGTGACCG CTGGATCCAG 
GATGAAATCG AGTTTGGCTA CATTGAGGCA CCCCACAAAG GCTTCCCAGT AGTGCTGGAC 
TCCCCTCGAG ATGGAAACCT GAAGGACTTC CCCATTAAGC AACTCCTGGG CCCAGATTTC 
GGCTATGTGA CCCGGGAGCC CCTCTTTGAG ACTGTCACCA GCCTCGACTC CTTCGGGAAT 
CTGGAGGTCA GTCCCCCAGT GACCGTGAAT GGCAAGGAGT ACCCGCTTGG CCGGATCCTC 
ATCGGAAGCA GTTTCCCCCT GTCTGGAGGC AGGAGGATGA CCAAGGTGGT ACGCGACTTC 
CTGCAGGCCC AGCAGGTGCA GGCGCCCGTG GAACTCTACT CCGACTGGCT GACTGTAGGC 
CACGTCGATG AGTTTATGAC TTTCATCCCC ATCCCAGGCA AAAAGGAATT TCGGCTGCTC 
ATGGCCAGCA CCTCCGCCTG CTACCAGCTC TTCCGAGAAA AGCAGAAGGC AGGCCACGGG 
GAGGCCGTTA TGTTCAAGGG CCTGGGAGGC ATGAGCAGCA AGCGCATCAC CATCAACAAG 
ATCCTGTCCA ATGAGAGCCT CACGCAGGAG AACCAGTACT TCCAGCGCTG TCTGGACTGG 
AACCGCGACA TCCTTAAGAG GGAGCTAGCG CTGACTGAGA AGGACATTAT TGACCTGCCC 
GCGCTCTTCA AGATGGATGA AAATCACCAG GCCAGGGCTT TCTTCCCTAA CATGGTGAAC 
ATGATCGTGC TAGACAAGGA CCTGGGCATC CCCAAGCCTT TCGGGCCCCA GGTGGAGGAG 
GAGTGCTGCC TGGAGACGCA CGTTCGAGGC CTGCTGGAGC CCCTGGGCCT CGCCTGCACG 
TTCATCGATG ACATCTCCGC CTACCACAAG TTCCTGGGAG AGGTTCACTG TGGCACCAAT 
GTCCGCAGGA AGCCGTTCAC CTTCAAGTGG TGGCACATGG TGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006538695.1
CDS	98..2185
Translation	MQPPIRENMLRERTVRLQYGSRVEAVYVLGTQLWTDVYSAAPAGAKTFSLKHSEGVKVEVVRDGEAEEVVTNGKQRWALSPSSTLRLSMAQASTEASSDKVTVNYYEEEGSAPIDQAGLFLTAIEISLDVDADRDGEVEKNNPKKASWTWGPEGQGAILLVNCDRDTPWLPKEDCSDEKVYSKQDLQDMSQMILRTKGPDRLPAGYEIVLYISMSDSDKVGVFYVENLQGVKKLLQELCRALVPGLCQYPFFGQRYIHILGRQKLYHVVKYTGGSAELLFFVEGLCFPDESFSGLVSIHVSLLEYMAEGIPLTPIFTDTVMFRIAPWIMTPNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYMNRGDRWIQDEIEFGYIEAPHKGFPVVLDSPRDGNLKDFPIKQLLGPDFGYVTREPLFETVTSLDSFGNLEVSPPVTVNGKEYPLGRILIGSSFPLSGGRRMTKVVRDFLQAQQVQAPVELYSDWLTVGHVDEFMTFIPIPGKKEFRLLMASTSACYQLFREKQKAGHGEAVMFKGLGGMSSKRITINKILSNESLTQENQYFQRCLDWNRDILKRELALTEKDIIDLPALFKMDENHQARAFFPNMVNMIVLDKDLGIPKPFGPQVEEECCLETHVRGLLEPLGLACTFIDDISAYHKFLGEVHCGTNVRRKPFTFKWWHMVP

Target ORF information:

RefSeq Version	XM_006538632.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus peptidyl arginine deiminase, type II (Padi2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006538632.3

ORF Insert Sequence:

ATGCAGCCGC CTATACGGGA AAATATGCTG CGGGAACGGA CCGTGCGGCT GCAGTATGGG 
AGCCGCGTGG AGGCGGTGTA CGTGCTGGGC ACGCAGCTCT GGACCGATGT CTACAGTGCA 
GCACCTGCTG GGGCCAAAAC CTTCAGCCTG AAGCACTCGG AAGGTGTGAA GGTGGAGGTC 
GTACGTGATG GAGAGGCAGA GGAGGTGGTC ACCAACGGCA AGCAGCGCTG GGCCCTGTCA 
CCCAGCAGCA CACTGCGGCT CAGCATGGCC CAGGCCAGCA CAGAGGCCAG CAGCGACAAG 
GTCACTGTCA ACTACTATGA AGAGGAGGGC AGCGCCCCCA TTGACCAGGC TGGGCTCTTC 
CTCACGGCCA TTGAGATCTC GCTGGATGTG GACGCAGATC GGGATGGAGA GGTGGAGAAG 
AACAATCCTA AGAAGGCATC CTGGACCTGG GGTCCTGAGG GCCAAGGGGC TATCCTGCTG 
GTGAATTGTG ACCGAGACAC ACCCTGGTTG CCCAAGGAGG ACTGTAGTGA CGAAAAGGTC 
TACAGCAAGC AAGACCTCCA GGACATGTCT CAGATGATCC TGCGCACCAA AGGCCCTGAC 
CGCCTGCCCG CCGGGTATGA AATAGTCCTC TACATCTCCA TGTCAGACTC GGACAAAGTG 
GGCGTCTTCT ACGTGGAGAA TTTGCAGGGC GTAAAGAAGC TGCTTCAGGA ACTCTGTAGG 
GCCCTAGTTC CAGGCCTTTG CCAATACCCG TTCTTTGGCC AGCGCTATAT CCACATCCTG 
GGCCGGCAGA AGCTCTACCA CGTGGTCAAG TACACCGGCG GTTCTGCGGA GTTGCTGTTC 
TTTGTGGAAG GCCTCTGTTT CCCCGACGAG AGTTTCTCAG GCCTGGTTTC TATCCACGTC 
AGTCTGCTGG AGTATATGGC CGAGGGCATC CCGTTGACCC CCATCTTCAC AGACACTGTG 
ATGTTCCGGA TTGCACCCTG GATTATGACC CCCAACATCT TGCCTCCTGT GTCAGTGTTC 
GTGTGCTGCA TGAAGGATAA TTACCTGTTC CTGAAAGAGG TGAAGAACTT GGTGGAGAAA 
ACCAACTGCG AACTGAAAGT TTGTTTCCAG TACATGAACC GCGGTGACCG CTGGATCCAG 
GATGAAATCG AGTTTGGCTA CATTGAGGCA CCCCACAAAG GCTTCCCAGT AGTGCTGGAC 
TCCCCTCGAG ATGGAAACCT GAAGGACTTC CCCATTAAGC AACTCCTGGG CCCAGATTTC 
GGCTATGTGA CCCGGGAGCC CCTCTTTGAG ACTGTCACCA GCCTCGACTC CTTCGGGAAT 
CTGGAGGTCA GTCCCCCAGT GACCGTGAAT GGCAAGGAGT ACCCGCTTGG CCGGATCCTC 
ATCGGAAGCA GTTTCCCCCT GTCTGGAGGC AGGAGGATGA CCAAGGTGGT ACGCGACTTC 
CTGCAGGCCC AGCAGGTGCA GGCGCCCGTG GAACTCTACT CCGACTGGCT GACTGTAGGC 
CACGTCGATG AGTTTATGAC TTTCATCCCC ATCCCAGGCA AAAAGGAATT TCGGCTGCTC 
ATGGCCAGCA CCTCCGCCTG CTACCAGCTC TTCCGAGAAA AGCAGAAGGC AGGCCACGGG 
GAGGCCGTTA TGTTCAAGGG CCTGGGAGGC ATGAGCAGCA AGCGCATCAC CATCAACAAG 
ATCCTGTCCA ATGAGAGCCT CACGCAGGAG AACCAGTACT TCCAGCGCTG TCTGGACTGG 
AACCGCGACA TCCTTAAGAG GGAGCTAGCG CTGACTGAGA AGGACATTAT TGACCTGCCC 
GCGCTCTTCA AGATGGATGA AAATCACCAG GCCAGGGCTT TCTTCCCTAA CATGGTGAAC 
ATGATCGTGC TAGACAAGGA CCTGGGCATC CCCAAGCCTT TCGGGCCCCA GGTGGAGGAG 
GAGTGCTGCC TGGAGACGCA CGTTCGAGGC CTGCTGGAGC CCCTGGGCCT CGCCTGCACG 
TTCATCGATG ACATCTCCGC CTACCACAAG TTCCTGGGAG AGGTTCACTG TGGCACCAAT 
GTCCGCAGGA AGCCGTTCAC CTTCAAGTGG TGGCACATGG TGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Padi2 ( XM_006538632.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006538695.1 Mus musculus peptidyl arginine deiminase, type II (Padi2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu34045
Clone ID Related Accession (Same CDS sequence)	XM_006538632.4 , XM_006538632.3
Accession Version	XM_006538632.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2088bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	protein-arginine deiminase type-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006538632.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCCGC CTATACGGGA AAATATGCTG CGGGAACGGA CCGTGCGGCT GCAGTATGGG 
AGCCGCGTGG AGGCGGTGTA CGTGCTGGGC ACGCAGCTCT GGACCGATGT CTACAGTGCA 
GCACCTGCTG GGGCCAAAAC CTTCAGCCTG AAGCACTCGG AAGGTGTGAA GGTGGAGGTC 
GTACGTGATG GAGAGGCAGA GGAGGTGGTC ACCAACGGCA AGCAGCGCTG GGCCCTGTCA 
CCCAGCAGCA CACTGCGGCT CAGCATGGCC CAGGCCAGCA CAGAGGCCAG CAGCGACAAG 
GTCACTGTCA ACTACTATGA AGAGGAGGGC AGCGCCCCCA TTGACCAGGC TGGGCTCTTC 
CTCACGGCCA TTGAGATCTC GCTGGATGTG GACGCAGATC GGGATGGAGA GGTGGAGAAG 
AACAATCCTA AGAAGGCATC CTGGACCTGG GGTCCTGAGG GCCAAGGGGC TATCCTGCTG 
GTGAATTGTG ACCGAGACAC ACCCTGGTTG CCCAAGGAGG ACTGTAGTGA CGAAAAGGTC 
TACAGCAAGC AAGACCTCCA GGACATGTCT CAGATGATCC TGCGCACCAA AGGCCCTGAC 
CGCCTGCCCG CCGGGTATGA AATAGTCCTC TACATCTCCA TGTCAGACTC GGACAAAGTG 
GGCGTCTTCT ACGTGGAGAA TTTGCAGGGC GTAAAGAAGC TGCTTCAGGA ACTCTGTAGG 
GCCCTAGTTC CAGGCCTTTG CCAATACCCG TTCTTTGGCC AGCGCTATAT CCACATCCTG 
GGCCGGCAGA AGCTCTACCA CGTGGTCAAG TACACCGGCG GTTCTGCGGA GTTGCTGTTC 
TTTGTGGAAG GCCTCTGTTT CCCCGACGAG AGTTTCTCAG GCCTGGTTTC TATCCACGTC 
AGTCTGCTGG AGTATATGGC CGAGGGCATC CCGTTGACCC CCATCTTCAC AGACACTGTG 
ATGTTCCGGA TTGCACCCTG GATTATGACC CCCAACATCT TGCCTCCTGT GTCAGTGTTC 
GTGTGCTGCA TGAAGGATAA TTACCTGTTC CTGAAAGAGG TGAAGAACTT GGTGGAGAAA 
ACCAACTGCG AACTGAAAGT TTGTTTCCAG TACATGAACC GCGGTGACCG CTGGATCCAG 
GATGAAATCG AGTTTGGCTA CATTGAGGCA CCCCACAAAG GCTTCCCAGT AGTGCTGGAC 
TCCCCTCGAG ATGGAAACCT GAAGGACTTC CCCATTAAGC AACTCCTGGG CCCAGATTTC 
GGCTATGTGA CCCGGGAGCC CCTCTTTGAG ACTGTCACCA GCCTCGACTC CTTCGGGAAT 
CTGGAGGTCA GTCCCCCAGT GACCGTGAAT GGCAAGGAGT ACCCGCTTGG CCGGATCCTC 
ATCGGAAGCA GTTTCCCCCT GTCTGGAGGC AGGAGGATGA CCAAGGTGGT ACGCGACTTC 
CTGCAGGCCC AGCAGGTGCA GGCGCCCGTG GAACTCTACT CCGACTGGCT GACTGTAGGC 
CACGTCGATG AGTTTATGAC TTTCATCCCC ATCCCAGGCA AAAAGGAATT TCGGCTGCTC 
ATGGCCAGCA CCTCCGCCTG CTACCAGCTC TTCCGAGAAA AGCAGAAGGC AGGCCACGGG 
GAGGCCGTTA TGTTCAAGGG CCTGGGAGGC ATGAGCAGCA AGCGCATCAC CATCAACAAG 
ATCCTGTCCA ATGAGAGCCT CACGCAGGAG AACCAGTACT TCCAGCGCTG TCTGGACTGG 
AACCGCGACA TCCTTAAGAG GGAGCTAGCG CTGACTGAGA AGGACATTAT TGACCTGCCC 
GCGCTCTTCA AGATGGATGA AAATCACCAG GCCAGGGCTT TCTTCCCTAA CATGGTGAAC 
ATGATCGTGC TAGACAAGGA CCTGGGCATC CCCAAGCCTT TCGGGCCCCA GGTGGAGGAG 
GAGTGCTGCC TGGAGACGCA CGTTCGAGGC CTGCTGGAGC CCCTGGGCCT CGCCTGCACG 
TTCATCGATG ACATCTCCGC CTACCACAAG TTCCTGGGAG AGGTTCACTG TGGCACCAAT 
GTCCGCAGGA AGCCGTTCAC CTTCAAGTGG TGGCACATGG TGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006538695.1
CDS	99..2186
Translation	MQPPIRENMLRERTVRLQYGSRVEAVYVLGTQLWTDVYSAAPAGAKTFSLKHSEGVKVEVVRDGEAEEVVTNGKQRWALSPSSTLRLSMAQASTEASSDKVTVNYYEEEGSAPIDQAGLFLTAIEISLDVDADRDGEVEKNNPKKASWTWGPEGQGAILLVNCDRDTPWLPKEDCSDEKVYSKQDLQDMSQMILRTKGPDRLPAGYEIVLYISMSDSDKVGVFYVENLQGVKKLLQELCRALVPGLCQYPFFGQRYIHILGRQKLYHVVKYTGGSAELLFFVEGLCFPDESFSGLVSIHVSLLEYMAEGIPLTPIFTDTVMFRIAPWIMTPNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYMNRGDRWIQDEIEFGYIEAPHKGFPVVLDSPRDGNLKDFPIKQLLGPDFGYVTREPLFETVTSLDSFGNLEVSPPVTVNGKEYPLGRILIGSSFPLSGGRRMTKVVRDFLQAQQVQAPVELYSDWLTVGHVDEFMTFIPIPGKKEFRLLMASTSACYQLFREKQKAGHGEAVMFKGLGGMSSKRITINKILSNESLTQENQYFQRCLDWNRDILKRELALTEKDIIDLPALFKMDENHQARAFFPNMVNMIVLDKDLGIPKPFGPQVEEECCLETHVRGLLEPLGLACTFIDDISAYHKFLGEVHCGTNVRRKPFTFKWWHMVP

Target ORF information:

RefSeq Version	XM_006538632.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus peptidyl arginine deiminase, type II (Padi2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006538632.4

ORF Insert Sequence:

ATGCAGCCGC CTATACGGGA AAATATGCTG CGGGAACGGA CCGTGCGGCT GCAGTATGGG 
AGCCGCGTGG AGGCGGTGTA CGTGCTGGGC ACGCAGCTCT GGACCGATGT CTACAGTGCA 
GCACCTGCTG GGGCCAAAAC CTTCAGCCTG AAGCACTCGG AAGGTGTGAA GGTGGAGGTC 
GTACGTGATG GAGAGGCAGA GGAGGTGGTC ACCAACGGCA AGCAGCGCTG GGCCCTGTCA 
CCCAGCAGCA CACTGCGGCT CAGCATGGCC CAGGCCAGCA CAGAGGCCAG CAGCGACAAG 
GTCACTGTCA ACTACTATGA AGAGGAGGGC AGCGCCCCCA TTGACCAGGC TGGGCTCTTC 
CTCACGGCCA TTGAGATCTC GCTGGATGTG GACGCAGATC GGGATGGAGA GGTGGAGAAG 
AACAATCCTA AGAAGGCATC CTGGACCTGG GGTCCTGAGG GCCAAGGGGC TATCCTGCTG 
GTGAATTGTG ACCGAGACAC ACCCTGGTTG CCCAAGGAGG ACTGTAGTGA CGAAAAGGTC 
TACAGCAAGC AAGACCTCCA GGACATGTCT CAGATGATCC TGCGCACCAA AGGCCCTGAC 
CGCCTGCCCG CCGGGTATGA AATAGTCCTC TACATCTCCA TGTCAGACTC GGACAAAGTG 
GGCGTCTTCT ACGTGGAGAA TTTGCAGGGC GTAAAGAAGC TGCTTCAGGA ACTCTGTAGG 
GCCCTAGTTC CAGGCCTTTG CCAATACCCG TTCTTTGGCC AGCGCTATAT CCACATCCTG 
GGCCGGCAGA AGCTCTACCA CGTGGTCAAG TACACCGGCG GTTCTGCGGA GTTGCTGTTC 
TTTGTGGAAG GCCTCTGTTT CCCCGACGAG AGTTTCTCAG GCCTGGTTTC TATCCACGTC 
AGTCTGCTGG AGTATATGGC CGAGGGCATC CCGTTGACCC CCATCTTCAC AGACACTGTG 
ATGTTCCGGA TTGCACCCTG GATTATGACC CCCAACATCT TGCCTCCTGT GTCAGTGTTC 
GTGTGCTGCA TGAAGGATAA TTACCTGTTC CTGAAAGAGG TGAAGAACTT GGTGGAGAAA 
ACCAACTGCG AACTGAAAGT TTGTTTCCAG TACATGAACC GCGGTGACCG CTGGATCCAG 
GATGAAATCG AGTTTGGCTA CATTGAGGCA CCCCACAAAG GCTTCCCAGT AGTGCTGGAC 
TCCCCTCGAG ATGGAAACCT GAAGGACTTC CCCATTAAGC AACTCCTGGG CCCAGATTTC 
GGCTATGTGA CCCGGGAGCC CCTCTTTGAG ACTGTCACCA GCCTCGACTC CTTCGGGAAT 
CTGGAGGTCA GTCCCCCAGT GACCGTGAAT GGCAAGGAGT ACCCGCTTGG CCGGATCCTC 
ATCGGAAGCA GTTTCCCCCT GTCTGGAGGC AGGAGGATGA CCAAGGTGGT ACGCGACTTC 
CTGCAGGCCC AGCAGGTGCA GGCGCCCGTG GAACTCTACT CCGACTGGCT GACTGTAGGC 
CACGTCGATG AGTTTATGAC TTTCATCCCC ATCCCAGGCA AAAAGGAATT TCGGCTGCTC 
ATGGCCAGCA CCTCCGCCTG CTACCAGCTC TTCCGAGAAA AGCAGAAGGC AGGCCACGGG 
GAGGCCGTTA TGTTCAAGGG CCTGGGAGGC ATGAGCAGCA AGCGCATCAC CATCAACAAG 
ATCCTGTCCA ATGAGAGCCT CACGCAGGAG AACCAGTACT TCCAGCGCTG TCTGGACTGG 
AACCGCGACA TCCTTAAGAG GGAGCTAGCG CTGACTGAGA AGGACATTAT TGACCTGCCC 
GCGCTCTTCA AGATGGATGA AAATCACCAG GCCAGGGCTT TCTTCCCTAA CATGGTGAAC 
ATGATCGTGC TAGACAAGGA CCTGGGCATC CCCAAGCCTT TCGGGCCCCA GGTGGAGGAG 
GAGTGCTGCC TGGAGACGCA CGTTCGAGGC CTGCTGGAGC CCCTGGGCCT CGCCTGCACG 
TTCATCGATG ACATCTCCGC CTACCACAAG TTCCTGGGAG AGGTTCACTG TGGCACCAAT 
GTCCGCAGGA AGCCGTTCAC CTTCAAGTGG TGGCACATGG TGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Peptidylarginine deiminase 2 is required for tumor necrosis factor alpha-induced citrullination and arthritis, but not neutrophil extracellular trap formation.
Journal of autoimmunity8039-47(2017 Jun)
Bawadekar M,Shim D,Johnson CJ,Warner TF,Rebernick R,Damgaard D,Nielsen CH,Pruijn GJM,Nett JE,Shelef MA

Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice.
PLoS genetics13(6)e1006848(2017 Jun)
Khajavi M,Zhou Y,Birsner AE,Bazinet L,Rosa Di Sant A,Schiffer AJ,Rogers MS,Krishnaji ST,Hu B,Nguyen V,Zon L,D'Amato RJ

Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development.
Scientific reports638727(2016 Dec)
Zhang X,Liu X,Zhang M,Li T,Muth A,Thompson PR,Coonrod SA,Zhang X

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Padi2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報