Pcsk1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pcsk1
Entrez Gene ID	18548
Full Name	proprotein convertase subtilisin/kexin type 1
Synonyms	Nec-1,Nec1,PC1,PC3,Phpp-1,SPC3
General protein information	Preferred Names proprotein convertase subtilisin/kexin type 1 Names neuroendocrine convertase 1 NEC 1 furin homolog prohormone convertase 1 prohormone convertase 1/3 propeptide-processing protease proprotein convertase 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13 C1\|13 40.63 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_013628.2	NP_038656.1	neuroendocrine convertase 1 precursor
XM_006517153.3	XP_006517216.1	neuroendocrine convertase 1 isoform X1
XM_006517153.2	XP_006517216.1	neuroendocrine convertase 1 isoform X1
XM_006517155.3	XP_006517218.1	neuroendocrine convertase 1 isoform X1
XM_006517155.2	XP_006517218.1	neuroendocrine convertase 1 isoform X1
XM_006517154.3	XP_006517217.1	neuroendocrine convertase 1 isoform X1
NM_013628.3	NP_038656.1	neuroendocrine convertase 1 precursor

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	pcsk1	XP_004910515.1
Homo sapiens (human)	PCSK1	NP_000430.3
Danio rerio (zebrafish)	pcsk1	NP_001131134.1
Bos taurus (cattle)	PCSK1	NP_776837.1
Gallus gallus (chicken)	PCSK1	XP_003643108.1
Caenorhabditis elegans (roundworm)	bli-4	NP_001021543.1
Canis lupus familiaris (dog)	PCSK1	XP_848637.1
Pan troglodytes (chimpanzee)	PCSK1	XP_001134900.1
	PCSK1	XP_002804496.1
Mus musculus (house mouse)	Pcsk1	NP_038656.1

Gene Ontology
Bibliography

Related articles in PubMed

Targeted high-resolution quadrupole-Orbitrap mass spectrometry analyses reveal a significant reduction of tachykinin and opioid neuropeptides level in PC1 and PC2 mutant mouse spinal cords.
Saidi M, Beaudry F
Neuropeptides6537-44(2017 Oct)

Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets.
Sinagoga KL, Stone WJ, Schiesser JV, Schweitzer JI, Sampson L, Zheng Y, Wells JM
Development (Cambridge, England)144(13)2402-2414(2017 07)

Pancreatic ? Cell-Derived Glucagon-Related Peptides Are Required for ? Cell Adaptation and Glucose Homeostasis.
Traub S, Meier DT, Schulze F, Dror E, Nordmann TM, Goetz N, Koch N, Dalmas E, Stawiski M, Makshana V, Thorel F, Herrera PL, B?ni-Schnetzler M, Donath MY
Cell reports18(13)3192-3203(2017 Mar)

Proprotein convertase 1 mediated proneuropeptide proteolytic processing in ischemic neuron injury.
Tang SS, Liang ZY, Guo LR, Zhang JH, Zhou D
Bratislavske lekarske listy118(10)609-612(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These pathways are consistent with previously reported behavioral and biochemical phenotypes that typify mice lacking ENT1. Moreover, we validated decreased expression of the SNARE complex protein VAMP1 (synaptobrevin-1) in the dHip as well as decreased expression of pro-dynorphin (PDYN), neuroendocrine convertase (PCSK1), and Leu-Enkephalin (dynorphin-A) in the nucleus accumbens
Title: Label-Free Neuroproteomics of the Hippocampal-Accumbal Circuit Reveals Deficits in Neurotransmitter and Neuropeptide Signaling in Mice Lacking Ethanol-Sensitive Adenosine Transporter.

findings suggest that the major neuroendocrine features of Prader-Willi syndrome are due to PC1 deficiency
Title: Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome.

investigation of the pathogenesis of obesity in the PC1/3-N222D mouse model and whether this molecular mechanism also applies to common and rare human PCSK1 mutations
Title: Endoplasmic reticulum-associated degradation of the mouse PC1/3-N222D hypomorph and human PCSK1 mutations contributes to obesity.

macrophages from PC1/3 KO mice and rat PC1/3-KD NR8383 macrophages secreted more pro-inflammatory cytokines such as TNF-alpha, IL6, IL1alpha and CXCL2.
Title: The proprotein convertase PC1/3 regulates TLR9 trafficking and the associated signaling pathways.

PC1 and PC2 are involved in the C-terminal processing of protachykinin peptides and suggest a major role in the maturation of the protachykinin-1 protein
Title: Tachykinins Processing is Significantly Impaired in PC1 and PC2 Mutant Mouse Spinal Cord S9 Fractions.

The following Pcsk1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pcsk1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu22796	NM_013628.3 Latest version!	Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu22796	XM_006517154.3 Latest version!	Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu22796	XM_006517155.3 Latest version!	Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu22796	XM_006517153.3 Latest version!	Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OMu22796	XM_006517153.2	Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu22796	XM_006517155.2	Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu22796	NM_013628.2	Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pcsk1 ( NM_013628.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038656.1 Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), mRNA.

Price & Availability↑

CloneID	OMu22796
Clone ID Related Accession (Same CDS sequence)	NM_013628.2 , XM_006517153.3 , XM_006517153.2 , XM_006517155.3 , XM_006517155.2 , XM_006517154.3 , NM_013628.3
Accession Version	NM_013628.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2262bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-27
Organism	Mus musculus(house mouse)
Product	neuroendocrine convertase 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC158543.2. On Nov 17, 2006 this sequence version replaced NM_013628.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660811.186983.1, BC108982.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN01164131 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCAAA GAGGTTGGAC TCTGCAGTGT ACTGCTTTCG CCTTCTTTTG CGTTTGGTGT 
GCACTAAACA GTGTAAAAGC AAAGAGGCAG TTTGTTAATG AATGGGCGGC GGAGATCCCC 
GGAGGGCAAG AAGCTGCCTC TGCCATCGCC GAAGAACTGG GGTATGACCT TTTGGGTCAG 
ATTGGATCAC TTGAAAATCA CTATTTATTC AAACACAAAA GCCATCCTCG GAGGTCCCGA 
AGAAGCGCTC TTCATATCAC TAAGAGGTTA TCTGATGATG ATCGTGTGAC GTGGGCTGAA 
CAACAGTATG AAAAAGAGAG AAGTAAACGT TCAGTTCAAA AAGACTCAGC ATTGGATCTC 
TTCAATGATC CAATGTGGAA TCAGCAGTGG TACTTGCAAG ATACCAGAAT GACTGCAGCT 
CTGCCCAAGC TGGACCTTCA TGTAATACCT GTTTGGGAAA AGGGTATTAC TGGCAAAGGA 
GTTGTTATTA CTGTACTGGA TGATGGCTTG GAGTGGAATC ACACAGACAT TTATGCCAAT 
TATGATCCAG AGGCTAGCTA TGATTTTAAC GATAATGATC ATGATCCATT TCCCCGATAT 
GATCTCACAA ATGAAAACAA ACATGGAACA AGATGTGCAG GTGAAATTGC CATGCAAGCA 
AATAATCACA AGTGTGGGGT TGGAGTTGCA TATAATTCCA AAGTTGGAGG CATAAGAATG 
CTGGATGGCA TTGTAACTGA TGCCATTGAG GCTAGTTCAA TTGGATTCAA CCCTGGCCAT 
GTGGATATTT ACAGTGCAAG CTGGGGCCCT AATGATGATG GAAAAACTGT GGAGGGGCCT 
GGCAGACTAG CCCAGAAGGC ATTTGAATAT GGTGTCAAAC AGGGGAGACA AGGGAAAGGC 
TCCATCTTTG TCTGGGCTTC AGGGAATGGG GGTCGTCAGG GAGATAACTG TGACTGTGAT 
GGCTACACAG ACAGCATTTA CACCATCTCT ATCAGCAGTG CCTCCCAGCA AGGCCTGTCA 
CCTTGGTATG CAGAGAAGTG TTCTTCCACA TTGGCTACCT CCTACAGCAG TGGTGATTAC 
ACAGACCAGC GAATAACAAG CGCTGACCTG CACAATGACT GCACAGAGAC CCACACAGGC 
ACCTCGGCTT CAGCACCCCT GGCTGCTGGT ATCTTTGCTC TGGCCTTGGA GGCAAACCCA 
AATCTTACCT GGAGAGATAT GCAGCATCTG GTTGTCTGGA CCTCTGAGTA CGACCCATTG 
GCCAGTAACC CAGGTTGGAA AAAGAATGGG GCAGGCTTGA TGGTGAACAG CCGATTTGGA 
TTTGGCTTGC TAAATGCCAA AGCTCTGGTG GATTTGGCTG ATCCTAGGAC CTGGAGAAAT 
GTGCCTGAGA AGAAAGAATG TGTTGTAAAA GACAATAACT TTGAGCCTAG AGCCCTGAAA 
GCTAATGGAG AAGTAATTGT TGAAATCCCA ACAAGAGCTT GTGAAGGACA AGAAAATGCT 
ATCAAGTCTC TGGAACATGT GCAATTTGAA GCAACAATTG AATATTCTCG TAGAGGAGAC 
CTTCATGTCA CACTCACTTC TGCTGTTGGA ACCAGCACTG TACTGTTGGC TGAAAGGGAA 
AGAGATACAT CCCCCAATGG CTTTAAGAAT TGGGACTTCA TGTCTGTTCA TACATGGGGA 
GAGAATCCTG TAGGCACCTG GACATTGAAA ATTACAGACA TGTCTGGAAG AATGCAAAAT 
GAAGGAAGGA TTGTGAACTG GAAGTTGATT TTGCATGGGA CATCTTCTCA ACCAGAGCAC 
ATGAAGCAGC CTCGTGTGTA CACATCCTAC AATACAGTCC AGAATGACAG GAGAGGAGTG 
GAAAAGATGG TGAATGTTGT GGAGAAGCGG CCCACACAAA AGAGCCTGAA TGGCAATCTC 
CTGGTACCCA AAAACTCCAG CAGCAGCAAT GTGGAGGGTA GAAGGGATGA GCAGGTACAA 
GGAACTCCTT CAAAGGCCAT GCTGCGACTC CTACAAAGTG CTTTTAGCAA GAATGCACTT 
TCAAAACAAT CACCAAAGAA GTCTCCAAGT GCAAAGCTCA GCATCCCTTA TGAAAGTTTC 
TATGAAGCCT TGGAAAAGCT CAACAAGCCC TCCAAGCTTG AAGGCTCTGA AGACAGTCTG 
TACAGTGACT ATGTTGATGT ATTCTATAAC ACAAAACCTT ATAAGCATAG AGATGACAGG 
CTGCTGCAAG CTCTCATGGA CATCCTAAAT GAGGAGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038656.1
CDS	76..2337
Translation	MEQRGWTLQCTAFAFFCVWCALNSVKAKRQFVNEWAAEIPGGQEAASAIAEELGYDLLGQIGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFEPRALKANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDMSGRMQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRGVEKMVNVVEKRPTQKSLNGNLLVPKNSSSSNVEGRRDEQVQGTPSKAMLRLLQSAFSKNALSKQSPKKSPSAKLSIPYESFYEALEKLNKPSKLEGSEDSLYSDYVDVFYNTKPYKHRDDRLLQALMDILNEEN

Target ORF information:

RefSeq Version	NM_013628.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013628.2

ORF Insert Sequence:

ATGGAGCAAA GAGGTTGGAC TCTGCAGTGT ACTGCTTTCG CCTTCTTTTG CGTTTGGTGT 
GCACTAAACA GTGTAAAAGC AAAGAGGCAG TTTGTTAATG AATGGGCGGC GGAGATCCCC 
GGAGGGCAAG AAGCTGCCTC TGCCATCGCC GAAGAACTGG GGTATGACCT TTTGGGTCAG 
ATTGGATCAC TTGAAAATCA CTATTTATTC AAACACAAAA GCCATCCTCG GAGGTCCCGA 
AGAAGCGCTC TTCATATCAC TAAGAGGTTA TCTGATGATG ATCGTGTGAC GTGGGCTGAA 
CAACAGTATG AAAAAGAGAG AAGTAAACGT TCAGTTCAAA AAGACTCAGC ATTGGATCTC 
TTCAATGATC CAATGTGGAA TCAGCAGTGG TACTTGCAAG ATACCAGAAT GACTGCAGCT 
CTGCCCAAGC TGGACCTTCA TGTAATACCT GTTTGGGAAA AGGGTATTAC TGGCAAAGGA 
GTTGTTATTA CTGTACTGGA TGATGGCTTG GAGTGGAATC ACACAGACAT TTATGCCAAT 
TATGATCCAG AGGCTAGCTA TGATTTTAAC GATAATGATC ATGATCCATT TCCCCGATAT 
GATCTCACAA ATGAAAACAA ACATGGAACA AGATGTGCAG GTGAAATTGC CATGCAAGCA 
AATAATCACA AGTGTGGGGT TGGAGTTGCA TATAATTCCA AAGTTGGAGG CATAAGAATG 
CTGGATGGCA TTGTAACTGA TGCCATTGAG GCTAGTTCAA TTGGATTCAA CCCTGGCCAT 
GTGGATATTT ACAGTGCAAG CTGGGGCCCT AATGATGATG GAAAAACTGT GGAGGGGCCT 
GGCAGACTAG CCCAGAAGGC ATTTGAATAT GGTGTCAAAC AGGGGAGACA AGGGAAAGGC 
TCCATCTTTG TCTGGGCTTC AGGGAATGGG GGTCGTCAGG GAGATAACTG TGACTGTGAT 
GGCTACACAG ACAGCATTTA CACCATCTCT ATCAGCAGTG CCTCCCAGCA AGGCCTGTCA 
CCTTGGTATG CAGAGAAGTG TTCTTCCACA TTGGCTACCT CCTACAGCAG TGGTGATTAC 
ACAGACCAGC GAATAACAAG CGCTGACCTG CACAATGACT GCACAGAGAC CCACACAGGC 
ACCTCGGCTT CAGCACCCCT GGCTGCTGGT ATCTTTGCTC TGGCCTTGGA GGCAAACCCA 
AATCTTACCT GGAGAGATAT GCAGCATCTG GTTGTCTGGA CCTCTGAGTA CGACCCATTG 
GCCAGTAACC CAGGTTGGAA AAAGAATGGG GCAGGCTTGA TGGTGAACAG CCGATTTGGA 
TTTGGCTTGC TAAATGCCAA AGCTCTGGTG GATTTGGCTG ATCCTAGGAC CTGGAGAAAT 
GTGCCTGAGA AGAAAGAATG TGTTGTAAAA GACAATAACT TTGAGCCTAG AGCCCTGAAA 
GCTAATGGAG AAGTAATTGT TGAAATCCCA ACAAGAGCTT GTGAAGGACA AGAAAATGCT 
ATCAAGTCTC TGGAACATGT GCAATTTGAA GCAACAATTG AATATTCTCG TAGAGGAGAC 
CTTCATGTCA CACTCACTTC TGCTGTTGGA ACCAGCACTG TACTGTTGGC TGAAAGGGAA 
AGAGATACAT CCCCCAATGG CTTTAAGAAT TGGGACTTCA TGTCTGTTCA TACATGGGGA 
GAGAATCCTG TAGGCACCTG GACATTGAAA ATTACAGACA TGTCTGGAAG AATGCAAAAT 
GAAGGAAGGA TTGTGAACTG GAAGTTGATT TTGCATGGGA CATCTTCTCA ACCAGAGCAC 
ATGAAGCAGC CTCGTGTGTA CACATCCTAC AATACAGTCC AGAATGACAG GAGAGGAGTG 
GAAAAGATGG TGAATGTTGT GGAGAAGCGG CCCACACAAA AGAGCCTGAA TGGCAATCTC 
CTGGTACCCA AAAACTCCAG CAGCAGCAAT GTGGAGGGTA GAAGGGATGA GCAGGTACAA 
GGAACTCCTT CAAAGGCCAT GCTGCGACTC CTACAAAGTG CTTTTAGCAA GAATGCACTT 
TCAAAACAAT CACCAAAGAA GTCTCCAAGT GCAAAGCTCA GCATCCCTTA TGAAAGTTTC 
TATGAAGCCT TGGAAAAGCT CAACAAGCCC TCCAAGCTTG AAGGCTCTGA AGACAGTCTG 
TACAGTGACT ATGTTGATGT ATTCTATAAC ACAAAACCTT ATAAGCATAG AGATGACAGG 
CTGCTGCAAG CTCTCATGGA CATCCTAAAT GAGGAGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pcsk1 ( NM_013628.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038656.1 Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), mRNA.

Price & Availability↑

CloneID	OMu22796
Clone ID Related Accession (Same CDS sequence)	NM_013628.2 , XM_006517153.3 , XM_006517153.2 , XM_006517155.3 , XM_006517155.2 , XM_006517154.3 , NM_013628.3
Accession Version	NM_013628.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2262bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-15
Organism	Mus musculus(house mouse)
Product	neuroendocrine convertase 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC158543.2. On Apr 13, 2018 this sequence version replaced NM_013628.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660811.186983.1, SRR1660811.63427.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAAA GAGGTTGGAC TCTGCAGTGT ACTGCTTTCG CCTTCTTTTG CGTTTGGTGT 
GCACTAAACA GTGTAAAAGC AAAGAGGCAG TTTGTTAATG AATGGGCGGC GGAGATCCCC 
GGAGGGCAAG AAGCTGCCTC TGCCATCGCC GAAGAACTGG GGTATGACCT TTTGGGTCAG 
ATTGGATCAC TTGAAAATCA CTATTTATTC AAACACAAAA GCCATCCTCG GAGGTCCCGA 
AGAAGCGCTC TTCATATCAC TAAGAGGTTA TCTGATGATG ATCGTGTGAC GTGGGCTGAA 
CAACAGTATG AAAAAGAGAG AAGTAAACGT TCAGTTCAAA AAGACTCAGC ATTGGATCTC 
TTCAATGATC CAATGTGGAA TCAGCAGTGG TACTTGCAAG ATACCAGAAT GACTGCAGCT 
CTGCCCAAGC TGGACCTTCA TGTAATACCT GTTTGGGAAA AGGGTATTAC TGGCAAAGGA 
GTTGTTATTA CTGTACTGGA TGATGGCTTG GAGTGGAATC ACACAGACAT TTATGCCAAT 
TATGATCCAG AGGCTAGCTA TGATTTTAAC GATAATGATC ATGATCCATT TCCCCGATAT 
GATCTCACAA ATGAAAACAA ACATGGAACA AGATGTGCAG GTGAAATTGC CATGCAAGCA 
AATAATCACA AGTGTGGGGT TGGAGTTGCA TATAATTCCA AAGTTGGAGG CATAAGAATG 
CTGGATGGCA TTGTAACTGA TGCCATTGAG GCTAGTTCAA TTGGATTCAA CCCTGGCCAT 
GTGGATATTT ACAGTGCAAG CTGGGGCCCT AATGATGATG GAAAAACTGT GGAGGGGCCT 
GGCAGACTAG CCCAGAAGGC ATTTGAATAT GGTGTCAAAC AGGGGAGACA AGGGAAAGGC 
TCCATCTTTG TCTGGGCTTC AGGGAATGGG GGTCGTCAGG GAGATAACTG TGACTGTGAT 
GGCTACACAG ACAGCATTTA CACCATCTCT ATCAGCAGTG CCTCCCAGCA AGGCCTGTCA 
CCTTGGTATG CAGAGAAGTG TTCTTCCACA TTGGCTACCT CCTACAGCAG TGGTGATTAC 
ACAGACCAGC GAATAACAAG CGCTGACCTG CACAATGACT GCACAGAGAC CCACACAGGC 
ACCTCGGCTT CAGCACCCCT GGCTGCTGGT ATCTTTGCTC TGGCCTTGGA GGCAAACCCA 
AATCTTACCT GGAGAGATAT GCAGCATCTG GTTGTCTGGA CCTCTGAGTA CGACCCATTG 
GCCAGTAACC CAGGTTGGAA AAAGAATGGG GCAGGCTTGA TGGTGAACAG CCGATTTGGA 
TTTGGCTTGC TAAATGCCAA AGCTCTGGTG GATTTGGCTG ATCCTAGGAC CTGGAGAAAT 
GTGCCTGAGA AGAAAGAATG TGTTGTAAAA GACAATAACT TTGAGCCTAG AGCCCTGAAA 
GCTAATGGAG AAGTAATTGT TGAAATCCCA ACAAGAGCTT GTGAAGGACA AGAAAATGCT 
ATCAAGTCTC TGGAACATGT GCAATTTGAA GCAACAATTG AATATTCTCG TAGAGGAGAC 
CTTCATGTCA CACTCACTTC TGCTGTTGGA ACCAGCACTG TACTGTTGGC TGAAAGGGAA 
AGAGATACAT CCCCCAATGG CTTTAAGAAT TGGGACTTCA TGTCTGTTCA TACATGGGGA 
GAGAATCCTG TAGGCACCTG GACATTGAAA ATTACAGACA TGTCTGGAAG AATGCAAAAT 
GAAGGAAGGA TTGTGAACTG GAAGTTGATT TTGCATGGGA CATCTTCTCA ACCAGAGCAC 
ATGAAGCAGC CTCGTGTGTA CACATCCTAC AATACAGTCC AGAATGACAG GAGAGGAGTG 
GAAAAGATGG TGAATGTTGT GGAGAAGCGG CCCACACAAA AGAGCCTGAA TGGCAATCTC 
CTGGTACCCA AAAACTCCAG CAGCAGCAAT GTGGAGGGTA GAAGGGATGA GCAGGTACAA 
GGAACTCCTT CAAAGGCCAT GCTGCGACTC CTACAAAGTG CTTTTAGCAA GAATGCACTT 
TCAAAACAAT CACCAAAGAA GTCTCCAAGT GCAAAGCTCA GCATCCCTTA TGAAAGTTTC 
TATGAAGCCT TGGAAAAGCT CAACAAGCCC TCCAAGCTTG AAGGCTCTGA AGACAGTCTG 
TACAGTGACT ATGTTGATGT ATTCTATAAC ACAAAACCTT ATAAGCATAG AGATGACAGG 
CTGCTGCAAG CTCTCATGGA CATCCTAAAT GAGGAGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038656.1
CDS	206..2467
Translation	MEQRGWTLQCTAFAFFCVWCALNSVKAKRQFVNEWAAEIPGGQEAASAIAEELGYDLLGQIGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFEPRALKANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDMSGRMQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRGVEKMVNVVEKRPTQKSLNGNLLVPKNSSSSNVEGRRDEQVQGTPSKAMLRLLQSAFSKNALSKQSPKKSPSAKLSIPYESFYEALEKLNKPSKLEGSEDSLYSDYVDVFYNTKPYKHRDDRLLQALMDILNEEN

Target ORF information:

RefSeq Version	NM_013628.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013628.3

ORF Insert Sequence:

ATGGAGCAAA GAGGTTGGAC TCTGCAGTGT ACTGCTTTCG CCTTCTTTTG CGTTTGGTGT 
GCACTAAACA GTGTAAAAGC AAAGAGGCAG TTTGTTAATG AATGGGCGGC GGAGATCCCC 
GGAGGGCAAG AAGCTGCCTC TGCCATCGCC GAAGAACTGG GGTATGACCT TTTGGGTCAG 
ATTGGATCAC TTGAAAATCA CTATTTATTC AAACACAAAA GCCATCCTCG GAGGTCCCGA 
AGAAGCGCTC TTCATATCAC TAAGAGGTTA TCTGATGATG ATCGTGTGAC GTGGGCTGAA 
CAACAGTATG AAAAAGAGAG AAGTAAACGT TCAGTTCAAA AAGACTCAGC ATTGGATCTC 
TTCAATGATC CAATGTGGAA TCAGCAGTGG TACTTGCAAG ATACCAGAAT GACTGCAGCT 
CTGCCCAAGC TGGACCTTCA TGTAATACCT GTTTGGGAAA AGGGTATTAC TGGCAAAGGA 
GTTGTTATTA CTGTACTGGA TGATGGCTTG GAGTGGAATC ACACAGACAT TTATGCCAAT 
TATGATCCAG AGGCTAGCTA TGATTTTAAC GATAATGATC ATGATCCATT TCCCCGATAT 
GATCTCACAA ATGAAAACAA ACATGGAACA AGATGTGCAG GTGAAATTGC CATGCAAGCA 
AATAATCACA AGTGTGGGGT TGGAGTTGCA TATAATTCCA AAGTTGGAGG CATAAGAATG 
CTGGATGGCA TTGTAACTGA TGCCATTGAG GCTAGTTCAA TTGGATTCAA CCCTGGCCAT 
GTGGATATTT ACAGTGCAAG CTGGGGCCCT AATGATGATG GAAAAACTGT GGAGGGGCCT 
GGCAGACTAG CCCAGAAGGC ATTTGAATAT GGTGTCAAAC AGGGGAGACA AGGGAAAGGC 
TCCATCTTTG TCTGGGCTTC AGGGAATGGG GGTCGTCAGG GAGATAACTG TGACTGTGAT 
GGCTACACAG ACAGCATTTA CACCATCTCT ATCAGCAGTG CCTCCCAGCA AGGCCTGTCA 
CCTTGGTATG CAGAGAAGTG TTCTTCCACA TTGGCTACCT CCTACAGCAG TGGTGATTAC 
ACAGACCAGC GAATAACAAG CGCTGACCTG CACAATGACT GCACAGAGAC CCACACAGGC 
ACCTCGGCTT CAGCACCCCT GGCTGCTGGT ATCTTTGCTC TGGCCTTGGA GGCAAACCCA 
AATCTTACCT GGAGAGATAT GCAGCATCTG GTTGTCTGGA CCTCTGAGTA CGACCCATTG 
GCCAGTAACC CAGGTTGGAA AAAGAATGGG GCAGGCTTGA TGGTGAACAG CCGATTTGGA 
TTTGGCTTGC TAAATGCCAA AGCTCTGGTG GATTTGGCTG ATCCTAGGAC CTGGAGAAAT 
GTGCCTGAGA AGAAAGAATG TGTTGTAAAA GACAATAACT TTGAGCCTAG AGCCCTGAAA 
GCTAATGGAG AAGTAATTGT TGAAATCCCA ACAAGAGCTT GTGAAGGACA AGAAAATGCT 
ATCAAGTCTC TGGAACATGT GCAATTTGAA GCAACAATTG AATATTCTCG TAGAGGAGAC 
CTTCATGTCA CACTCACTTC TGCTGTTGGA ACCAGCACTG TACTGTTGGC TGAAAGGGAA 
AGAGATACAT CCCCCAATGG CTTTAAGAAT TGGGACTTCA TGTCTGTTCA TACATGGGGA 
GAGAATCCTG TAGGCACCTG GACATTGAAA ATTACAGACA TGTCTGGAAG AATGCAAAAT 
GAAGGAAGGA TTGTGAACTG GAAGTTGATT TTGCATGGGA CATCTTCTCA ACCAGAGCAC 
ATGAAGCAGC CTCGTGTGTA CACATCCTAC AATACAGTCC AGAATGACAG GAGAGGAGTG 
GAAAAGATGG TGAATGTTGT GGAGAAGCGG CCCACACAAA AGAGCCTGAA TGGCAATCTC 
CTGGTACCCA AAAACTCCAG CAGCAGCAAT GTGGAGGGTA GAAGGGATGA GCAGGTACAA 
GGAACTCCTT CAAAGGCCAT GCTGCGACTC CTACAAAGTG CTTTTAGCAA GAATGCACTT 
TCAAAACAAT CACCAAAGAA GTCTCCAAGT GCAAAGCTCA GCATCCCTTA TGAAAGTTTC 
TATGAAGCCT TGGAAAAGCT CAACAAGCCC TCCAAGCTTG AAGGCTCTGA AGACAGTCTG 
TACAGTGACT ATGTTGATGT ATTCTATAAC ACAAAACCTT ATAAGCATAG AGATGACAGG 
CTGCTGCAAG CTCTCATGGA CATCCTAAAT GAGGAGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pcsk1 ( XM_006517153.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517216.1 Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X1, mRNA.

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CloneID	OMu22796
Clone ID Related Accession (Same CDS sequence)	NM_013628.2 , XM_006517153.3 , XM_006517153.2 , XM_006517155.3 , XM_006517155.2 , XM_006517154.3 , NM_013628.3
Accession Version	XM_006517153.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2262bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	neuroendocrine convertase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006517153.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCAAA GAGGTTGGAC TCTGCAGTGT ACTGCTTTCG CCTTCTTTTG CGTTTGGTGT 
GCACTAAACA GTGTAAAAGC AAAGAGGCAG TTTGTTAATG AATGGGCGGC GGAGATCCCC 
GGAGGGCAAG AAGCTGCCTC TGCCATCGCC GAAGAACTGG GGTATGACCT TTTGGGTCAG 
ATTGGATCAC TTGAAAATCA CTATTTATTC AAACACAAAA GCCATCCTCG GAGGTCCCGA 
AGAAGCGCTC TTCATATCAC TAAGAGGTTA TCTGATGATG ATCGTGTGAC GTGGGCTGAA 
CAACAGTATG AAAAAGAGAG AAGTAAACGT TCAGTTCAAA AAGACTCAGC ATTGGATCTC 
TTCAATGATC CAATGTGGAA TCAGCAGTGG TACTTGCAAG ATACCAGAAT GACTGCAGCT 
CTGCCCAAGC TGGACCTTCA TGTAATACCT GTTTGGGAAA AGGGTATTAC TGGCAAAGGA 
GTTGTTATTA CTGTACTGGA TGATGGCTTG GAGTGGAATC ACACAGACAT TTATGCCAAT 
TATGATCCAG AGGCTAGCTA TGATTTTAAC GATAATGATC ATGATCCATT TCCCCGATAT 
GATCTCACAA ATGAAAACAA ACATGGAACA AGATGTGCAG GTGAAATTGC CATGCAAGCA 
AATAATCACA AGTGTGGGGT TGGAGTTGCA TATAATTCCA AAGTTGGAGG CATAAGAATG 
CTGGATGGCA TTGTAACTGA TGCCATTGAG GCTAGTTCAA TTGGATTCAA CCCTGGCCAT 
GTGGATATTT ACAGTGCAAG CTGGGGCCCT AATGATGATG GAAAAACTGT GGAGGGGCCT 
GGCAGACTAG CCCAGAAGGC ATTTGAATAT GGTGTCAAAC AGGGGAGACA AGGGAAAGGC 
TCCATCTTTG TCTGGGCTTC AGGGAATGGG GGTCGTCAGG GAGATAACTG TGACTGTGAT 
GGCTACACAG ACAGCATTTA CACCATCTCT ATCAGCAGTG CCTCCCAGCA AGGCCTGTCA 
CCTTGGTATG CAGAGAAGTG TTCTTCCACA TTGGCTACCT CCTACAGCAG TGGTGATTAC 
ACAGACCAGC GAATAACAAG CGCTGACCTG CACAATGACT GCACAGAGAC CCACACAGGC 
ACCTCGGCTT CAGCACCCCT GGCTGCTGGT ATCTTTGCTC TGGCCTTGGA GGCAAACCCA 
AATCTTACCT GGAGAGATAT GCAGCATCTG GTTGTCTGGA CCTCTGAGTA CGACCCATTG 
GCCAGTAACC CAGGTTGGAA AAAGAATGGG GCAGGCTTGA TGGTGAACAG CCGATTTGGA 
TTTGGCTTGC TAAATGCCAA AGCTCTGGTG GATTTGGCTG ATCCTAGGAC CTGGAGAAAT 
GTGCCTGAGA AGAAAGAATG TGTTGTAAAA GACAATAACT TTGAGCCTAG AGCCCTGAAA 
GCTAATGGAG AAGTAATTGT TGAAATCCCA ACAAGAGCTT GTGAAGGACA AGAAAATGCT 
ATCAAGTCTC TGGAACATGT GCAATTTGAA GCAACAATTG AATATTCTCG TAGAGGAGAC 
CTTCATGTCA CACTCACTTC TGCTGTTGGA ACCAGCACTG TACTGTTGGC TGAAAGGGAA 
AGAGATACAT CCCCCAATGG CTTTAAGAAT TGGGACTTCA TGTCTGTTCA TACATGGGGA 
GAGAATCCTG TAGGCACCTG GACATTGAAA ATTACAGACA TGTCTGGAAG AATGCAAAAT 
GAAGGAAGGA TTGTGAACTG GAAGTTGATT TTGCATGGGA CATCTTCTCA ACCAGAGCAC 
ATGAAGCAGC CTCGTGTGTA CACATCCTAC AATACAGTCC AGAATGACAG GAGAGGAGTG 
GAAAAGATGG TGAATGTTGT GGAGAAGCGG CCCACACAAA AGAGCCTGAA TGGCAATCTC 
CTGGTACCCA AAAACTCCAG CAGCAGCAAT GTGGAGGGTA GAAGGGATGA GCAGGTACAA 
GGAACTCCTT CAAAGGCCAT GCTGCGACTC CTACAAAGTG CTTTTAGCAA GAATGCACTT 
TCAAAACAAT CACCAAAGAA GTCTCCAAGT GCAAAGCTCA GCATCCCTTA TGAAAGTTTC 
TATGAAGCCT TGGAAAAGCT CAACAAGCCC TCCAAGCTTG AAGGCTCTGA AGACAGTCTG 
TACAGTGACT ATGTTGATGT ATTCTATAAC ACAAAACCTT ATAAGCATAG AGATGACAGG 
CTGCTGCAAG CTCTCATGGA CATCCTAAAT GAGGAGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517216.1
CDS	191..2452
Translation	MEQRGWTLQCTAFAFFCVWCALNSVKAKRQFVNEWAAEIPGGQEAASAIAEELGYDLLGQIGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFEPRALKANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDMSGRMQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRGVEKMVNVVEKRPTQKSLNGNLLVPKNSSSSNVEGRRDEQVQGTPSKAMLRLLQSAFSKNALSKQSPKKSPSAKLSIPYESFYEALEKLNKPSKLEGSEDSLYSDYVDVFYNTKPYKHRDDRLLQALMDILNEEN

Target ORF information:

RefSeq Version	XM_006517153.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517153.2

ORF Insert Sequence:

ATGGAGCAAA GAGGTTGGAC TCTGCAGTGT ACTGCTTTCG CCTTCTTTTG CGTTTGGTGT 
GCACTAAACA GTGTAAAAGC AAAGAGGCAG TTTGTTAATG AATGGGCGGC GGAGATCCCC 
GGAGGGCAAG AAGCTGCCTC TGCCATCGCC GAAGAACTGG GGTATGACCT TTTGGGTCAG 
ATTGGATCAC TTGAAAATCA CTATTTATTC AAACACAAAA GCCATCCTCG GAGGTCCCGA 
AGAAGCGCTC TTCATATCAC TAAGAGGTTA TCTGATGATG ATCGTGTGAC GTGGGCTGAA 
CAACAGTATG AAAAAGAGAG AAGTAAACGT TCAGTTCAAA AAGACTCAGC ATTGGATCTC 
TTCAATGATC CAATGTGGAA TCAGCAGTGG TACTTGCAAG ATACCAGAAT GACTGCAGCT 
CTGCCCAAGC TGGACCTTCA TGTAATACCT GTTTGGGAAA AGGGTATTAC TGGCAAAGGA 
GTTGTTATTA CTGTACTGGA TGATGGCTTG GAGTGGAATC ACACAGACAT TTATGCCAAT 
TATGATCCAG AGGCTAGCTA TGATTTTAAC GATAATGATC ATGATCCATT TCCCCGATAT 
GATCTCACAA ATGAAAACAA ACATGGAACA AGATGTGCAG GTGAAATTGC CATGCAAGCA 
AATAATCACA AGTGTGGGGT TGGAGTTGCA TATAATTCCA AAGTTGGAGG CATAAGAATG 
CTGGATGGCA TTGTAACTGA TGCCATTGAG GCTAGTTCAA TTGGATTCAA CCCTGGCCAT 
GTGGATATTT ACAGTGCAAG CTGGGGCCCT AATGATGATG GAAAAACTGT GGAGGGGCCT 
GGCAGACTAG CCCAGAAGGC ATTTGAATAT GGTGTCAAAC AGGGGAGACA AGGGAAAGGC 
TCCATCTTTG TCTGGGCTTC AGGGAATGGG GGTCGTCAGG GAGATAACTG TGACTGTGAT 
GGCTACACAG ACAGCATTTA CACCATCTCT ATCAGCAGTG CCTCCCAGCA AGGCCTGTCA 
CCTTGGTATG CAGAGAAGTG TTCTTCCACA TTGGCTACCT CCTACAGCAG TGGTGATTAC 
ACAGACCAGC GAATAACAAG CGCTGACCTG CACAATGACT GCACAGAGAC CCACACAGGC 
ACCTCGGCTT CAGCACCCCT GGCTGCTGGT ATCTTTGCTC TGGCCTTGGA GGCAAACCCA 
AATCTTACCT GGAGAGATAT GCAGCATCTG GTTGTCTGGA CCTCTGAGTA CGACCCATTG 
GCCAGTAACC CAGGTTGGAA AAAGAATGGG GCAGGCTTGA TGGTGAACAG CCGATTTGGA 
TTTGGCTTGC TAAATGCCAA AGCTCTGGTG GATTTGGCTG ATCCTAGGAC CTGGAGAAAT 
GTGCCTGAGA AGAAAGAATG TGTTGTAAAA GACAATAACT TTGAGCCTAG AGCCCTGAAA 
GCTAATGGAG AAGTAATTGT TGAAATCCCA ACAAGAGCTT GTGAAGGACA AGAAAATGCT 
ATCAAGTCTC TGGAACATGT GCAATTTGAA GCAACAATTG AATATTCTCG TAGAGGAGAC 
CTTCATGTCA CACTCACTTC TGCTGTTGGA ACCAGCACTG TACTGTTGGC TGAAAGGGAA 
AGAGATACAT CCCCCAATGG CTTTAAGAAT TGGGACTTCA TGTCTGTTCA TACATGGGGA 
GAGAATCCTG TAGGCACCTG GACATTGAAA ATTACAGACA TGTCTGGAAG AATGCAAAAT 
GAAGGAAGGA TTGTGAACTG GAAGTTGATT TTGCATGGGA CATCTTCTCA ACCAGAGCAC 
ATGAAGCAGC CTCGTGTGTA CACATCCTAC AATACAGTCC AGAATGACAG GAGAGGAGTG 
GAAAAGATGG TGAATGTTGT GGAGAAGCGG CCCACACAAA AGAGCCTGAA TGGCAATCTC 
CTGGTACCCA AAAACTCCAG CAGCAGCAAT GTGGAGGGTA GAAGGGATGA GCAGGTACAA 
GGAACTCCTT CAAAGGCCAT GCTGCGACTC CTACAAAGTG CTTTTAGCAA GAATGCACTT 
TCAAAACAAT CACCAAAGAA GTCTCCAAGT GCAAAGCTCA GCATCCCTTA TGAAAGTTTC 
TATGAAGCCT TGGAAAAGCT CAACAAGCCC TCCAAGCTTG AAGGCTCTGA AGACAGTCTG 
TACAGTGACT ATGTTGATGT ATTCTATAAC ACAAAACCTT ATAAGCATAG AGATGACAGG 
CTGCTGCAAG CTCTCATGGA CATCCTAAAT GAGGAGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pcsk1 ( XM_006517155.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517218.1 Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu22796
Clone ID Related Accession (Same CDS sequence)	NM_013628.2 , XM_006517153.3 , XM_006517153.2 , XM_006517155.3 , XM_006517155.2 , XM_006517154.3 , NM_013628.3
Accession Version	XM_006517155.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2262bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	neuroendocrine convertase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006517155.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCAAA GAGGTTGGAC TCTGCAGTGT ACTGCTTTCG CCTTCTTTTG CGTTTGGTGT 
GCACTAAACA GTGTAAAAGC AAAGAGGCAG TTTGTTAATG AATGGGCGGC GGAGATCCCC 
GGAGGGCAAG AAGCTGCCTC TGCCATCGCC GAAGAACTGG GGTATGACCT TTTGGGTCAG 
ATTGGATCAC TTGAAAATCA CTATTTATTC AAACACAAAA GCCATCCTCG GAGGTCCCGA 
AGAAGCGCTC TTCATATCAC TAAGAGGTTA TCTGATGATG ATCGTGTGAC GTGGGCTGAA 
CAACAGTATG AAAAAGAGAG AAGTAAACGT TCAGTTCAAA AAGACTCAGC ATTGGATCTC 
TTCAATGATC CAATGTGGAA TCAGCAGTGG TACTTGCAAG ATACCAGAAT GACTGCAGCT 
CTGCCCAAGC TGGACCTTCA TGTAATACCT GTTTGGGAAA AGGGTATTAC TGGCAAAGGA 
GTTGTTATTA CTGTACTGGA TGATGGCTTG GAGTGGAATC ACACAGACAT TTATGCCAAT 
TATGATCCAG AGGCTAGCTA TGATTTTAAC GATAATGATC ATGATCCATT TCCCCGATAT 
GATCTCACAA ATGAAAACAA ACATGGAACA AGATGTGCAG GTGAAATTGC CATGCAAGCA 
AATAATCACA AGTGTGGGGT TGGAGTTGCA TATAATTCCA AAGTTGGAGG CATAAGAATG 
CTGGATGGCA TTGTAACTGA TGCCATTGAG GCTAGTTCAA TTGGATTCAA CCCTGGCCAT 
GTGGATATTT ACAGTGCAAG CTGGGGCCCT AATGATGATG GAAAAACTGT GGAGGGGCCT 
GGCAGACTAG CCCAGAAGGC ATTTGAATAT GGTGTCAAAC AGGGGAGACA AGGGAAAGGC 
TCCATCTTTG TCTGGGCTTC AGGGAATGGG GGTCGTCAGG GAGATAACTG TGACTGTGAT 
GGCTACACAG ACAGCATTTA CACCATCTCT ATCAGCAGTG CCTCCCAGCA AGGCCTGTCA 
CCTTGGTATG CAGAGAAGTG TTCTTCCACA TTGGCTACCT CCTACAGCAG TGGTGATTAC 
ACAGACCAGC GAATAACAAG CGCTGACCTG CACAATGACT GCACAGAGAC CCACACAGGC 
ACCTCGGCTT CAGCACCCCT GGCTGCTGGT ATCTTTGCTC TGGCCTTGGA GGCAAACCCA 
AATCTTACCT GGAGAGATAT GCAGCATCTG GTTGTCTGGA CCTCTGAGTA CGACCCATTG 
GCCAGTAACC CAGGTTGGAA AAAGAATGGG GCAGGCTTGA TGGTGAACAG CCGATTTGGA 
TTTGGCTTGC TAAATGCCAA AGCTCTGGTG GATTTGGCTG ATCCTAGGAC CTGGAGAAAT 
GTGCCTGAGA AGAAAGAATG TGTTGTAAAA GACAATAACT TTGAGCCTAG AGCCCTGAAA 
GCTAATGGAG AAGTAATTGT TGAAATCCCA ACAAGAGCTT GTGAAGGACA AGAAAATGCT 
ATCAAGTCTC TGGAACATGT GCAATTTGAA GCAACAATTG AATATTCTCG TAGAGGAGAC 
CTTCATGTCA CACTCACTTC TGCTGTTGGA ACCAGCACTG TACTGTTGGC TGAAAGGGAA 
AGAGATACAT CCCCCAATGG CTTTAAGAAT TGGGACTTCA TGTCTGTTCA TACATGGGGA 
GAGAATCCTG TAGGCACCTG GACATTGAAA ATTACAGACA TGTCTGGAAG AATGCAAAAT 
GAAGGAAGGA TTGTGAACTG GAAGTTGATT TTGCATGGGA CATCTTCTCA ACCAGAGCAC 
ATGAAGCAGC CTCGTGTGTA CACATCCTAC AATACAGTCC AGAATGACAG GAGAGGAGTG 
GAAAAGATGG TGAATGTTGT GGAGAAGCGG CCCACACAAA AGAGCCTGAA TGGCAATCTC 
CTGGTACCCA AAAACTCCAG CAGCAGCAAT GTGGAGGGTA GAAGGGATGA GCAGGTACAA 
GGAACTCCTT CAAAGGCCAT GCTGCGACTC CTACAAAGTG CTTTTAGCAA GAATGCACTT 
TCAAAACAAT CACCAAAGAA GTCTCCAAGT GCAAAGCTCA GCATCCCTTA TGAAAGTTTC 
TATGAAGCCT TGGAAAAGCT CAACAAGCCC TCCAAGCTTG AAGGCTCTGA AGACAGTCTG 
TACAGTGACT ATGTTGATGT ATTCTATAAC ACAAAACCTT ATAAGCATAG AGATGACAGG 
CTGCTGCAAG CTCTCATGGA CATCCTAAAT GAGGAGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517218.1
CDS	150..2411
Translation	MEQRGWTLQCTAFAFFCVWCALNSVKAKRQFVNEWAAEIPGGQEAASAIAEELGYDLLGQIGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFEPRALKANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDMSGRMQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRGVEKMVNVVEKRPTQKSLNGNLLVPKNSSSSNVEGRRDEQVQGTPSKAMLRLLQSAFSKNALSKQSPKKSPSAKLSIPYESFYEALEKLNKPSKLEGSEDSLYSDYVDVFYNTKPYKHRDDRLLQALMDILNEEN

Target ORF information:

RefSeq Version	XM_006517155.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517155.2

ORF Insert Sequence:

ATGGAGCAAA GAGGTTGGAC TCTGCAGTGT ACTGCTTTCG CCTTCTTTTG CGTTTGGTGT 
GCACTAAACA GTGTAAAAGC AAAGAGGCAG TTTGTTAATG AATGGGCGGC GGAGATCCCC 
GGAGGGCAAG AAGCTGCCTC TGCCATCGCC GAAGAACTGG GGTATGACCT TTTGGGTCAG 
ATTGGATCAC TTGAAAATCA CTATTTATTC AAACACAAAA GCCATCCTCG GAGGTCCCGA 
AGAAGCGCTC TTCATATCAC TAAGAGGTTA TCTGATGATG ATCGTGTGAC GTGGGCTGAA 
CAACAGTATG AAAAAGAGAG AAGTAAACGT TCAGTTCAAA AAGACTCAGC ATTGGATCTC 
TTCAATGATC CAATGTGGAA TCAGCAGTGG TACTTGCAAG ATACCAGAAT GACTGCAGCT 
CTGCCCAAGC TGGACCTTCA TGTAATACCT GTTTGGGAAA AGGGTATTAC TGGCAAAGGA 
GTTGTTATTA CTGTACTGGA TGATGGCTTG GAGTGGAATC ACACAGACAT TTATGCCAAT 
TATGATCCAG AGGCTAGCTA TGATTTTAAC GATAATGATC ATGATCCATT TCCCCGATAT 
GATCTCACAA ATGAAAACAA ACATGGAACA AGATGTGCAG GTGAAATTGC CATGCAAGCA 
AATAATCACA AGTGTGGGGT TGGAGTTGCA TATAATTCCA AAGTTGGAGG CATAAGAATG 
CTGGATGGCA TTGTAACTGA TGCCATTGAG GCTAGTTCAA TTGGATTCAA CCCTGGCCAT 
GTGGATATTT ACAGTGCAAG CTGGGGCCCT AATGATGATG GAAAAACTGT GGAGGGGCCT 
GGCAGACTAG CCCAGAAGGC ATTTGAATAT GGTGTCAAAC AGGGGAGACA AGGGAAAGGC 
TCCATCTTTG TCTGGGCTTC AGGGAATGGG GGTCGTCAGG GAGATAACTG TGACTGTGAT 
GGCTACACAG ACAGCATTTA CACCATCTCT ATCAGCAGTG CCTCCCAGCA AGGCCTGTCA 
CCTTGGTATG CAGAGAAGTG TTCTTCCACA TTGGCTACCT CCTACAGCAG TGGTGATTAC 
ACAGACCAGC GAATAACAAG CGCTGACCTG CACAATGACT GCACAGAGAC CCACACAGGC 
ACCTCGGCTT CAGCACCCCT GGCTGCTGGT ATCTTTGCTC TGGCCTTGGA GGCAAACCCA 
AATCTTACCT GGAGAGATAT GCAGCATCTG GTTGTCTGGA CCTCTGAGTA CGACCCATTG 
GCCAGTAACC CAGGTTGGAA AAAGAATGGG GCAGGCTTGA TGGTGAACAG CCGATTTGGA 
TTTGGCTTGC TAAATGCCAA AGCTCTGGTG GATTTGGCTG ATCCTAGGAC CTGGAGAAAT 
GTGCCTGAGA AGAAAGAATG TGTTGTAAAA GACAATAACT TTGAGCCTAG AGCCCTGAAA 
GCTAATGGAG AAGTAATTGT TGAAATCCCA ACAAGAGCTT GTGAAGGACA AGAAAATGCT 
ATCAAGTCTC TGGAACATGT GCAATTTGAA GCAACAATTG AATATTCTCG TAGAGGAGAC 
CTTCATGTCA CACTCACTTC TGCTGTTGGA ACCAGCACTG TACTGTTGGC TGAAAGGGAA 
AGAGATACAT CCCCCAATGG CTTTAAGAAT TGGGACTTCA TGTCTGTTCA TACATGGGGA 
GAGAATCCTG TAGGCACCTG GACATTGAAA ATTACAGACA TGTCTGGAAG AATGCAAAAT 
GAAGGAAGGA TTGTGAACTG GAAGTTGATT TTGCATGGGA CATCTTCTCA ACCAGAGCAC 
ATGAAGCAGC CTCGTGTGTA CACATCCTAC AATACAGTCC AGAATGACAG GAGAGGAGTG 
GAAAAGATGG TGAATGTTGT GGAGAAGCGG CCCACACAAA AGAGCCTGAA TGGCAATCTC 
CTGGTACCCA AAAACTCCAG CAGCAGCAAT GTGGAGGGTA GAAGGGATGA GCAGGTACAA 
GGAACTCCTT CAAAGGCCAT GCTGCGACTC CTACAAAGTG CTTTTAGCAA GAATGCACTT 
TCAAAACAAT CACCAAAGAA GTCTCCAAGT GCAAAGCTCA GCATCCCTTA TGAAAGTTTC 
TATGAAGCCT TGGAAAAGCT CAACAAGCCC TCCAAGCTTG AAGGCTCTGA AGACAGTCTG 
TACAGTGACT ATGTTGATGT ATTCTATAAC ACAAAACCTT ATAAGCATAG AGATGACAGG 
CTGCTGCAAG CTCTCATGGA CATCCTAAAT GAGGAGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pcsk1 ( XM_006517154.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517217.1 Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X2, mRNA.

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CloneID	OMu22796
Clone ID Related Accession (Same CDS sequence)	NM_013628.2 , XM_006517153.3 , XM_006517153.2 , XM_006517155.3 , XM_006517155.2 , XM_006517154.3 , NM_013628.3
Accession Version	XM_006517154.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2262bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	neuroendocrine convertase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006517154.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCAAA GAGGTTGGAC TCTGCAGTGT ACTGCTTTCG CCTTCTTTTG CGTTTGGTGT 
GCACTAAACA GTGTAAAAGC AAAGAGGCAG TTTGTTAATG AATGGGCGGC GGAGATCCCC 
GGAGGGCAAG AAGCTGCCTC TGCCATCGCC GAAGAACTGG GGTATGACCT TTTGGGTCAG 
ATTGGATCAC TTGAAAATCA CTATTTATTC AAACACAAAA GCCATCCTCG GAGGTCCCGA 
AGAAGCGCTC TTCATATCAC TAAGAGGTTA TCTGATGATG ATCGTGTGAC GTGGGCTGAA 
CAACAGTATG AAAAAGAGAG AAGTAAACGT TCAGTTCAAA AAGACTCAGC ATTGGATCTC 
TTCAATGATC CAATGTGGAA TCAGCAGTGG TACTTGCAAG ATACCAGAAT GACTGCAGCT 
CTGCCCAAGC TGGACCTTCA TGTAATACCT GTTTGGGAAA AGGGTATTAC TGGCAAAGGA 
GTTGTTATTA CTGTACTGGA TGATGGCTTG GAGTGGAATC ACACAGACAT TTATGCCAAT 
TATGATCCAG AGGCTAGCTA TGATTTTAAC GATAATGATC ATGATCCATT TCCCCGATAT 
GATCTCACAA ATGAAAACAA ACATGGAACA AGATGTGCAG GTGAAATTGC CATGCAAGCA 
AATAATCACA AGTGTGGGGT TGGAGTTGCA TATAATTCCA AAGTTGGAGG CATAAGAATG 
CTGGATGGCA TTGTAACTGA TGCCATTGAG GCTAGTTCAA TTGGATTCAA CCCTGGCCAT 
GTGGATATTT ACAGTGCAAG CTGGGGCCCT AATGATGATG GAAAAACTGT GGAGGGGCCT 
GGCAGACTAG CCCAGAAGGC ATTTGAATAT GGTGTCAAAC AGGGGAGACA AGGGAAAGGC 
TCCATCTTTG TCTGGGCTTC AGGGAATGGG GGTCGTCAGG GAGATAACTG TGACTGTGAT 
GGCTACACAG ACAGCATTTA CACCATCTCT ATCAGCAGTG CCTCCCAGCA AGGCCTGTCA 
CCTTGGTATG CAGAGAAGTG TTCTTCCACA TTGGCTACCT CCTACAGCAG TGGTGATTAC 
ACAGACCAGC GAATAACAAG CGCTGACCTG CACAATGACT GCACAGAGAC CCACACAGGC 
ACCTCGGCTT CAGCACCCCT GGCTGCTGGT ATCTTTGCTC TGGCCTTGGA GGCAAACCCA 
AATCTTACCT GGAGAGATAT GCAGCATCTG GTTGTCTGGA CCTCTGAGTA CGACCCATTG 
GCCAGTAACC CAGGTTGGAA AAAGAATGGG GCAGGCTTGA TGGTGAACAG CCGATTTGGA 
TTTGGCTTGC TAAATGCCAA AGCTCTGGTG GATTTGGCTG ATCCTAGGAC CTGGAGAAAT 
GTGCCTGAGA AGAAAGAATG TGTTGTAAAA GACAATAACT TTGAGCCTAG AGCCCTGAAA 
GCTAATGGAG AAGTAATTGT TGAAATCCCA ACAAGAGCTT GTGAAGGACA AGAAAATGCT 
ATCAAGTCTC TGGAACATGT GCAATTTGAA GCAACAATTG AATATTCTCG TAGAGGAGAC 
CTTCATGTCA CACTCACTTC TGCTGTTGGA ACCAGCACTG TACTGTTGGC TGAAAGGGAA 
AGAGATACAT CCCCCAATGG CTTTAAGAAT TGGGACTTCA TGTCTGTTCA TACATGGGGA 
GAGAATCCTG TAGGCACCTG GACATTGAAA ATTACAGACA TGTCTGGAAG AATGCAAAAT 
GAAGGAAGGA TTGTGAACTG GAAGTTGATT TTGCATGGGA CATCTTCTCA ACCAGAGCAC 
ATGAAGCAGC CTCGTGTGTA CACATCCTAC AATACAGTCC AGAATGACAG GAGAGGAGTG 
GAAAAGATGG TGAATGTTGT GGAGAAGCGG CCCACACAAA AGAGCCTGAA TGGCAATCTC 
CTGGTACCCA AAAACTCCAG CAGCAGCAAT GTGGAGGGTA GAAGGGATGA GCAGGTACAA 
GGAACTCCTT CAAAGGCCAT GCTGCGACTC CTACAAAGTG CTTTTAGCAA GAATGCACTT 
TCAAAACAAT CACCAAAGAA GTCTCCAAGT GCAAAGCTCA GCATCCCTTA TGAAAGTTTC 
TATGAAGCCT TGGAAAAGCT CAACAAGCCC TCCAAGCTTG AAGGCTCTGA AGACAGTCTG 
TACAGTGACT ATGTTGATGT ATTCTATAAC ACAAAACCTT ATAAGCATAG AGATGACAGG 
CTGCTGCAAG CTCTCATGGA CATCCTAAAT GAGGAGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517217.1
CDS	120..2381
Translation	MEQRGWTLQCTAFAFFCVWCALNSVKAKRQFVNEWAAEIPGGQEAASAIAEELGYDLLGQIGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFEPRALKANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDMSGRMQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRGVEKMVNVVEKRPTQKSLNGNLLVPKNSSSSNVEGRRDEQVQGTPSKAMLRLLQSAFSKNALSKQSPKKSPSAKLSIPYESFYEALEKLNKPSKLEGSEDSLYSDYVDVFYNTKPYKHRDDRLLQALMDILNEEN

Target ORF information:

RefSeq Version	XM_006517154.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517154.3

ORF Insert Sequence:

ATGGAGCAAA GAGGTTGGAC TCTGCAGTGT ACTGCTTTCG CCTTCTTTTG CGTTTGGTGT 
GCACTAAACA GTGTAAAAGC AAAGAGGCAG TTTGTTAATG AATGGGCGGC GGAGATCCCC 
GGAGGGCAAG AAGCTGCCTC TGCCATCGCC GAAGAACTGG GGTATGACCT TTTGGGTCAG 
ATTGGATCAC TTGAAAATCA CTATTTATTC AAACACAAAA GCCATCCTCG GAGGTCCCGA 
AGAAGCGCTC TTCATATCAC TAAGAGGTTA TCTGATGATG ATCGTGTGAC GTGGGCTGAA 
CAACAGTATG AAAAAGAGAG AAGTAAACGT TCAGTTCAAA AAGACTCAGC ATTGGATCTC 
TTCAATGATC CAATGTGGAA TCAGCAGTGG TACTTGCAAG ATACCAGAAT GACTGCAGCT 
CTGCCCAAGC TGGACCTTCA TGTAATACCT GTTTGGGAAA AGGGTATTAC TGGCAAAGGA 
GTTGTTATTA CTGTACTGGA TGATGGCTTG GAGTGGAATC ACACAGACAT TTATGCCAAT 
TATGATCCAG AGGCTAGCTA TGATTTTAAC GATAATGATC ATGATCCATT TCCCCGATAT 
GATCTCACAA ATGAAAACAA ACATGGAACA AGATGTGCAG GTGAAATTGC CATGCAAGCA 
AATAATCACA AGTGTGGGGT TGGAGTTGCA TATAATTCCA AAGTTGGAGG CATAAGAATG 
CTGGATGGCA TTGTAACTGA TGCCATTGAG GCTAGTTCAA TTGGATTCAA CCCTGGCCAT 
GTGGATATTT ACAGTGCAAG CTGGGGCCCT AATGATGATG GAAAAACTGT GGAGGGGCCT 
GGCAGACTAG CCCAGAAGGC ATTTGAATAT GGTGTCAAAC AGGGGAGACA AGGGAAAGGC 
TCCATCTTTG TCTGGGCTTC AGGGAATGGG GGTCGTCAGG GAGATAACTG TGACTGTGAT 
GGCTACACAG ACAGCATTTA CACCATCTCT ATCAGCAGTG CCTCCCAGCA AGGCCTGTCA 
CCTTGGTATG CAGAGAAGTG TTCTTCCACA TTGGCTACCT CCTACAGCAG TGGTGATTAC 
ACAGACCAGC GAATAACAAG CGCTGACCTG CACAATGACT GCACAGAGAC CCACACAGGC 
ACCTCGGCTT CAGCACCCCT GGCTGCTGGT ATCTTTGCTC TGGCCTTGGA GGCAAACCCA 
AATCTTACCT GGAGAGATAT GCAGCATCTG GTTGTCTGGA CCTCTGAGTA CGACCCATTG 
GCCAGTAACC CAGGTTGGAA AAAGAATGGG GCAGGCTTGA TGGTGAACAG CCGATTTGGA 
TTTGGCTTGC TAAATGCCAA AGCTCTGGTG GATTTGGCTG ATCCTAGGAC CTGGAGAAAT 
GTGCCTGAGA AGAAAGAATG TGTTGTAAAA GACAATAACT TTGAGCCTAG AGCCCTGAAA 
GCTAATGGAG AAGTAATTGT TGAAATCCCA ACAAGAGCTT GTGAAGGACA AGAAAATGCT 
ATCAAGTCTC TGGAACATGT GCAATTTGAA GCAACAATTG AATATTCTCG TAGAGGAGAC 
CTTCATGTCA CACTCACTTC TGCTGTTGGA ACCAGCACTG TACTGTTGGC TGAAAGGGAA 
AGAGATACAT CCCCCAATGG CTTTAAGAAT TGGGACTTCA TGTCTGTTCA TACATGGGGA 
GAGAATCCTG TAGGCACCTG GACATTGAAA ATTACAGACA TGTCTGGAAG AATGCAAAAT 
GAAGGAAGGA TTGTGAACTG GAAGTTGATT TTGCATGGGA CATCTTCTCA ACCAGAGCAC 
ATGAAGCAGC CTCGTGTGTA CACATCCTAC AATACAGTCC AGAATGACAG GAGAGGAGTG 
GAAAAGATGG TGAATGTTGT GGAGAAGCGG CCCACACAAA AGAGCCTGAA TGGCAATCTC 
CTGGTACCCA AAAACTCCAG CAGCAGCAAT GTGGAGGGTA GAAGGGATGA GCAGGTACAA 
GGAACTCCTT CAAAGGCCAT GCTGCGACTC CTACAAAGTG CTTTTAGCAA GAATGCACTT 
TCAAAACAAT CACCAAAGAA GTCTCCAAGT GCAAAGCTCA GCATCCCTTA TGAAAGTTTC 
TATGAAGCCT TGGAAAAGCT CAACAAGCCC TCCAAGCTTG AAGGCTCTGA AGACAGTCTG 
TACAGTGACT ATGTTGATGT ATTCTATAAC ACAAAACCTT ATAAGCATAG AGATGACAGG 
CTGCTGCAAG CTCTCATGGA CATCCTAAAT GAGGAGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pcsk1 ( XM_006517153.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517216.1 Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X1, mRNA.

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CloneID	OMu22796
Clone ID Related Accession (Same CDS sequence)	NM_013628.2 , XM_006517153.3 , XM_006517153.2 , XM_006517155.3 , XM_006517155.2 , XM_006517154.3 , NM_013628.3
Accession Version	XM_006517153.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2262bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	neuroendocrine convertase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006517153.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCAAA GAGGTTGGAC TCTGCAGTGT ACTGCTTTCG CCTTCTTTTG CGTTTGGTGT 
GCACTAAACA GTGTAAAAGC AAAGAGGCAG TTTGTTAATG AATGGGCGGC GGAGATCCCC 
GGAGGGCAAG AAGCTGCCTC TGCCATCGCC GAAGAACTGG GGTATGACCT TTTGGGTCAG 
ATTGGATCAC TTGAAAATCA CTATTTATTC AAACACAAAA GCCATCCTCG GAGGTCCCGA 
AGAAGCGCTC TTCATATCAC TAAGAGGTTA TCTGATGATG ATCGTGTGAC GTGGGCTGAA 
CAACAGTATG AAAAAGAGAG AAGTAAACGT TCAGTTCAAA AAGACTCAGC ATTGGATCTC 
TTCAATGATC CAATGTGGAA TCAGCAGTGG TACTTGCAAG ATACCAGAAT GACTGCAGCT 
CTGCCCAAGC TGGACCTTCA TGTAATACCT GTTTGGGAAA AGGGTATTAC TGGCAAAGGA 
GTTGTTATTA CTGTACTGGA TGATGGCTTG GAGTGGAATC ACACAGACAT TTATGCCAAT 
TATGATCCAG AGGCTAGCTA TGATTTTAAC GATAATGATC ATGATCCATT TCCCCGATAT 
GATCTCACAA ATGAAAACAA ACATGGAACA AGATGTGCAG GTGAAATTGC CATGCAAGCA 
AATAATCACA AGTGTGGGGT TGGAGTTGCA TATAATTCCA AAGTTGGAGG CATAAGAATG 
CTGGATGGCA TTGTAACTGA TGCCATTGAG GCTAGTTCAA TTGGATTCAA CCCTGGCCAT 
GTGGATATTT ACAGTGCAAG CTGGGGCCCT AATGATGATG GAAAAACTGT GGAGGGGCCT 
GGCAGACTAG CCCAGAAGGC ATTTGAATAT GGTGTCAAAC AGGGGAGACA AGGGAAAGGC 
TCCATCTTTG TCTGGGCTTC AGGGAATGGG GGTCGTCAGG GAGATAACTG TGACTGTGAT 
GGCTACACAG ACAGCATTTA CACCATCTCT ATCAGCAGTG CCTCCCAGCA AGGCCTGTCA 
CCTTGGTATG CAGAGAAGTG TTCTTCCACA TTGGCTACCT CCTACAGCAG TGGTGATTAC 
ACAGACCAGC GAATAACAAG CGCTGACCTG CACAATGACT GCACAGAGAC CCACACAGGC 
ACCTCGGCTT CAGCACCCCT GGCTGCTGGT ATCTTTGCTC TGGCCTTGGA GGCAAACCCA 
AATCTTACCT GGAGAGATAT GCAGCATCTG GTTGTCTGGA CCTCTGAGTA CGACCCATTG 
GCCAGTAACC CAGGTTGGAA AAAGAATGGG GCAGGCTTGA TGGTGAACAG CCGATTTGGA 
TTTGGCTTGC TAAATGCCAA AGCTCTGGTG GATTTGGCTG ATCCTAGGAC CTGGAGAAAT 
GTGCCTGAGA AGAAAGAATG TGTTGTAAAA GACAATAACT TTGAGCCTAG AGCCCTGAAA 
GCTAATGGAG AAGTAATTGT TGAAATCCCA ACAAGAGCTT GTGAAGGACA AGAAAATGCT 
ATCAAGTCTC TGGAACATGT GCAATTTGAA GCAACAATTG AATATTCTCG TAGAGGAGAC 
CTTCATGTCA CACTCACTTC TGCTGTTGGA ACCAGCACTG TACTGTTGGC TGAAAGGGAA 
AGAGATACAT CCCCCAATGG CTTTAAGAAT TGGGACTTCA TGTCTGTTCA TACATGGGGA 
GAGAATCCTG TAGGCACCTG GACATTGAAA ATTACAGACA TGTCTGGAAG AATGCAAAAT 
GAAGGAAGGA TTGTGAACTG GAAGTTGATT TTGCATGGGA CATCTTCTCA ACCAGAGCAC 
ATGAAGCAGC CTCGTGTGTA CACATCCTAC AATACAGTCC AGAATGACAG GAGAGGAGTG 
GAAAAGATGG TGAATGTTGT GGAGAAGCGG CCCACACAAA AGAGCCTGAA TGGCAATCTC 
CTGGTACCCA AAAACTCCAG CAGCAGCAAT GTGGAGGGTA GAAGGGATGA GCAGGTACAA 
GGAACTCCTT CAAAGGCCAT GCTGCGACTC CTACAAAGTG CTTTTAGCAA GAATGCACTT 
TCAAAACAAT CACCAAAGAA GTCTCCAAGT GCAAAGCTCA GCATCCCTTA TGAAAGTTTC 
TATGAAGCCT TGGAAAAGCT CAACAAGCCC TCCAAGCTTG AAGGCTCTGA AGACAGTCTG 
TACAGTGACT ATGTTGATGT ATTCTATAAC ACAAAACCTT ATAAGCATAG AGATGACAGG 
CTGCTGCAAG CTCTCATGGA CATCCTAAAT GAGGAGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517216.1
CDS	189..2450
Translation	MEQRGWTLQCTAFAFFCVWCALNSVKAKRQFVNEWAAEIPGGQEAASAIAEELGYDLLGQIGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFEPRALKANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDMSGRMQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRGVEKMVNVVEKRPTQKSLNGNLLVPKNSSSSNVEGRRDEQVQGTPSKAMLRLLQSAFSKNALSKQSPKKSPSAKLSIPYESFYEALEKLNKPSKLEGSEDSLYSDYVDVFYNTKPYKHRDDRLLQALMDILNEEN

Target ORF information:

RefSeq Version	XM_006517153.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517153.3

ORF Insert Sequence:

ATGGAGCAAA GAGGTTGGAC TCTGCAGTGT ACTGCTTTCG CCTTCTTTTG CGTTTGGTGT 
GCACTAAACA GTGTAAAAGC AAAGAGGCAG TTTGTTAATG AATGGGCGGC GGAGATCCCC 
GGAGGGCAAG AAGCTGCCTC TGCCATCGCC GAAGAACTGG GGTATGACCT TTTGGGTCAG 
ATTGGATCAC TTGAAAATCA CTATTTATTC AAACACAAAA GCCATCCTCG GAGGTCCCGA 
AGAAGCGCTC TTCATATCAC TAAGAGGTTA TCTGATGATG ATCGTGTGAC GTGGGCTGAA 
CAACAGTATG AAAAAGAGAG AAGTAAACGT TCAGTTCAAA AAGACTCAGC ATTGGATCTC 
TTCAATGATC CAATGTGGAA TCAGCAGTGG TACTTGCAAG ATACCAGAAT GACTGCAGCT 
CTGCCCAAGC TGGACCTTCA TGTAATACCT GTTTGGGAAA AGGGTATTAC TGGCAAAGGA 
GTTGTTATTA CTGTACTGGA TGATGGCTTG GAGTGGAATC ACACAGACAT TTATGCCAAT 
TATGATCCAG AGGCTAGCTA TGATTTTAAC GATAATGATC ATGATCCATT TCCCCGATAT 
GATCTCACAA ATGAAAACAA ACATGGAACA AGATGTGCAG GTGAAATTGC CATGCAAGCA 
AATAATCACA AGTGTGGGGT TGGAGTTGCA TATAATTCCA AAGTTGGAGG CATAAGAATG 
CTGGATGGCA TTGTAACTGA TGCCATTGAG GCTAGTTCAA TTGGATTCAA CCCTGGCCAT 
GTGGATATTT ACAGTGCAAG CTGGGGCCCT AATGATGATG GAAAAACTGT GGAGGGGCCT 
GGCAGACTAG CCCAGAAGGC ATTTGAATAT GGTGTCAAAC AGGGGAGACA AGGGAAAGGC 
TCCATCTTTG TCTGGGCTTC AGGGAATGGG GGTCGTCAGG GAGATAACTG TGACTGTGAT 
GGCTACACAG ACAGCATTTA CACCATCTCT ATCAGCAGTG CCTCCCAGCA AGGCCTGTCA 
CCTTGGTATG CAGAGAAGTG TTCTTCCACA TTGGCTACCT CCTACAGCAG TGGTGATTAC 
ACAGACCAGC GAATAACAAG CGCTGACCTG CACAATGACT GCACAGAGAC CCACACAGGC 
ACCTCGGCTT CAGCACCCCT GGCTGCTGGT ATCTTTGCTC TGGCCTTGGA GGCAAACCCA 
AATCTTACCT GGAGAGATAT GCAGCATCTG GTTGTCTGGA CCTCTGAGTA CGACCCATTG 
GCCAGTAACC CAGGTTGGAA AAAGAATGGG GCAGGCTTGA TGGTGAACAG CCGATTTGGA 
TTTGGCTTGC TAAATGCCAA AGCTCTGGTG GATTTGGCTG ATCCTAGGAC CTGGAGAAAT 
GTGCCTGAGA AGAAAGAATG TGTTGTAAAA GACAATAACT TTGAGCCTAG AGCCCTGAAA 
GCTAATGGAG AAGTAATTGT TGAAATCCCA ACAAGAGCTT GTGAAGGACA AGAAAATGCT 
ATCAAGTCTC TGGAACATGT GCAATTTGAA GCAACAATTG AATATTCTCG TAGAGGAGAC 
CTTCATGTCA CACTCACTTC TGCTGTTGGA ACCAGCACTG TACTGTTGGC TGAAAGGGAA 
AGAGATACAT CCCCCAATGG CTTTAAGAAT TGGGACTTCA TGTCTGTTCA TACATGGGGA 
GAGAATCCTG TAGGCACCTG GACATTGAAA ATTACAGACA TGTCTGGAAG AATGCAAAAT 
GAAGGAAGGA TTGTGAACTG GAAGTTGATT TTGCATGGGA CATCTTCTCA ACCAGAGCAC 
ATGAAGCAGC CTCGTGTGTA CACATCCTAC AATACAGTCC AGAATGACAG GAGAGGAGTG 
GAAAAGATGG TGAATGTTGT GGAGAAGCGG CCCACACAAA AGAGCCTGAA TGGCAATCTC 
CTGGTACCCA AAAACTCCAG CAGCAGCAAT GTGGAGGGTA GAAGGGATGA GCAGGTACAA 
GGAACTCCTT CAAAGGCCAT GCTGCGACTC CTACAAAGTG CTTTTAGCAA GAATGCACTT 
TCAAAACAAT CACCAAAGAA GTCTCCAAGT GCAAAGCTCA GCATCCCTTA TGAAAGTTTC 
TATGAAGCCT TGGAAAAGCT CAACAAGCCC TCCAAGCTTG AAGGCTCTGA AGACAGTCTG 
TACAGTGACT ATGTTGATGT ATTCTATAAC ACAAAACCTT ATAAGCATAG AGATGACAGG 
CTGCTGCAAG CTCTCATGGA CATCCTAAAT GAGGAGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pcsk1 ( XM_006517155.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517218.1 Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu22796
Clone ID Related Accession (Same CDS sequence)	NM_013628.2 , XM_006517153.3 , XM_006517153.2 , XM_006517155.3 , XM_006517155.2 , XM_006517154.3 , NM_013628.3
Accession Version	XM_006517155.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2262bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	neuroendocrine convertase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006517155.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCAAA GAGGTTGGAC TCTGCAGTGT ACTGCTTTCG CCTTCTTTTG CGTTTGGTGT 
GCACTAAACA GTGTAAAAGC AAAGAGGCAG TTTGTTAATG AATGGGCGGC GGAGATCCCC 
GGAGGGCAAG AAGCTGCCTC TGCCATCGCC GAAGAACTGG GGTATGACCT TTTGGGTCAG 
ATTGGATCAC TTGAAAATCA CTATTTATTC AAACACAAAA GCCATCCTCG GAGGTCCCGA 
AGAAGCGCTC TTCATATCAC TAAGAGGTTA TCTGATGATG ATCGTGTGAC GTGGGCTGAA 
CAACAGTATG AAAAAGAGAG AAGTAAACGT TCAGTTCAAA AAGACTCAGC ATTGGATCTC 
TTCAATGATC CAATGTGGAA TCAGCAGTGG TACTTGCAAG ATACCAGAAT GACTGCAGCT 
CTGCCCAAGC TGGACCTTCA TGTAATACCT GTTTGGGAAA AGGGTATTAC TGGCAAAGGA 
GTTGTTATTA CTGTACTGGA TGATGGCTTG GAGTGGAATC ACACAGACAT TTATGCCAAT 
TATGATCCAG AGGCTAGCTA TGATTTTAAC GATAATGATC ATGATCCATT TCCCCGATAT 
GATCTCACAA ATGAAAACAA ACATGGAACA AGATGTGCAG GTGAAATTGC CATGCAAGCA 
AATAATCACA AGTGTGGGGT TGGAGTTGCA TATAATTCCA AAGTTGGAGG CATAAGAATG 
CTGGATGGCA TTGTAACTGA TGCCATTGAG GCTAGTTCAA TTGGATTCAA CCCTGGCCAT 
GTGGATATTT ACAGTGCAAG CTGGGGCCCT AATGATGATG GAAAAACTGT GGAGGGGCCT 
GGCAGACTAG CCCAGAAGGC ATTTGAATAT GGTGTCAAAC AGGGGAGACA AGGGAAAGGC 
TCCATCTTTG TCTGGGCTTC AGGGAATGGG GGTCGTCAGG GAGATAACTG TGACTGTGAT 
GGCTACACAG ACAGCATTTA CACCATCTCT ATCAGCAGTG CCTCCCAGCA AGGCCTGTCA 
CCTTGGTATG CAGAGAAGTG TTCTTCCACA TTGGCTACCT CCTACAGCAG TGGTGATTAC 
ACAGACCAGC GAATAACAAG CGCTGACCTG CACAATGACT GCACAGAGAC CCACACAGGC 
ACCTCGGCTT CAGCACCCCT GGCTGCTGGT ATCTTTGCTC TGGCCTTGGA GGCAAACCCA 
AATCTTACCT GGAGAGATAT GCAGCATCTG GTTGTCTGGA CCTCTGAGTA CGACCCATTG 
GCCAGTAACC CAGGTTGGAA AAAGAATGGG GCAGGCTTGA TGGTGAACAG CCGATTTGGA 
TTTGGCTTGC TAAATGCCAA AGCTCTGGTG GATTTGGCTG ATCCTAGGAC CTGGAGAAAT 
GTGCCTGAGA AGAAAGAATG TGTTGTAAAA GACAATAACT TTGAGCCTAG AGCCCTGAAA 
GCTAATGGAG AAGTAATTGT TGAAATCCCA ACAAGAGCTT GTGAAGGACA AGAAAATGCT 
ATCAAGTCTC TGGAACATGT GCAATTTGAA GCAACAATTG AATATTCTCG TAGAGGAGAC 
CTTCATGTCA CACTCACTTC TGCTGTTGGA ACCAGCACTG TACTGTTGGC TGAAAGGGAA 
AGAGATACAT CCCCCAATGG CTTTAAGAAT TGGGACTTCA TGTCTGTTCA TACATGGGGA 
GAGAATCCTG TAGGCACCTG GACATTGAAA ATTACAGACA TGTCTGGAAG AATGCAAAAT 
GAAGGAAGGA TTGTGAACTG GAAGTTGATT TTGCATGGGA CATCTTCTCA ACCAGAGCAC 
ATGAAGCAGC CTCGTGTGTA CACATCCTAC AATACAGTCC AGAATGACAG GAGAGGAGTG 
GAAAAGATGG TGAATGTTGT GGAGAAGCGG CCCACACAAA AGAGCCTGAA TGGCAATCTC 
CTGGTACCCA AAAACTCCAG CAGCAGCAAT GTGGAGGGTA GAAGGGATGA GCAGGTACAA 
GGAACTCCTT CAAAGGCCAT GCTGCGACTC CTACAAAGTG CTTTTAGCAA GAATGCACTT 
TCAAAACAAT CACCAAAGAA GTCTCCAAGT GCAAAGCTCA GCATCCCTTA TGAAAGTTTC 
TATGAAGCCT TGGAAAAGCT CAACAAGCCC TCCAAGCTTG AAGGCTCTGA AGACAGTCTG 
TACAGTGACT ATGTTGATGT ATTCTATAAC ACAAAACCTT ATAAGCATAG AGATGACAGG 
CTGCTGCAAG CTCTCATGGA CATCCTAAAT GAGGAGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517218.1
CDS	148..2409
Translation	MEQRGWTLQCTAFAFFCVWCALNSVKAKRQFVNEWAAEIPGGQEAASAIAEELGYDLLGQIGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFEPRALKANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDMSGRMQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRGVEKMVNVVEKRPTQKSLNGNLLVPKNSSSSNVEGRRDEQVQGTPSKAMLRLLQSAFSKNALSKQSPKKSPSAKLSIPYESFYEALEKLNKPSKLEGSEDSLYSDYVDVFYNTKPYKHRDDRLLQALMDILNEEN

Target ORF information:

RefSeq Version	XM_006517155.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus proprotein convertase subtilisin/kexin type 1 (Pcsk1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517155.3

ORF Insert Sequence:

ATGGAGCAAA GAGGTTGGAC TCTGCAGTGT ACTGCTTTCG CCTTCTTTTG CGTTTGGTGT 
GCACTAAACA GTGTAAAAGC AAAGAGGCAG TTTGTTAATG AATGGGCGGC GGAGATCCCC 
GGAGGGCAAG AAGCTGCCTC TGCCATCGCC GAAGAACTGG GGTATGACCT TTTGGGTCAG 
ATTGGATCAC TTGAAAATCA CTATTTATTC AAACACAAAA GCCATCCTCG GAGGTCCCGA 
AGAAGCGCTC TTCATATCAC TAAGAGGTTA TCTGATGATG ATCGTGTGAC GTGGGCTGAA 
CAACAGTATG AAAAAGAGAG AAGTAAACGT TCAGTTCAAA AAGACTCAGC ATTGGATCTC 
TTCAATGATC CAATGTGGAA TCAGCAGTGG TACTTGCAAG ATACCAGAAT GACTGCAGCT 
CTGCCCAAGC TGGACCTTCA TGTAATACCT GTTTGGGAAA AGGGTATTAC TGGCAAAGGA 
GTTGTTATTA CTGTACTGGA TGATGGCTTG GAGTGGAATC ACACAGACAT TTATGCCAAT 
TATGATCCAG AGGCTAGCTA TGATTTTAAC GATAATGATC ATGATCCATT TCCCCGATAT 
GATCTCACAA ATGAAAACAA ACATGGAACA AGATGTGCAG GTGAAATTGC CATGCAAGCA 
AATAATCACA AGTGTGGGGT TGGAGTTGCA TATAATTCCA AAGTTGGAGG CATAAGAATG 
CTGGATGGCA TTGTAACTGA TGCCATTGAG GCTAGTTCAA TTGGATTCAA CCCTGGCCAT 
GTGGATATTT ACAGTGCAAG CTGGGGCCCT AATGATGATG GAAAAACTGT GGAGGGGCCT 
GGCAGACTAG CCCAGAAGGC ATTTGAATAT GGTGTCAAAC AGGGGAGACA AGGGAAAGGC 
TCCATCTTTG TCTGGGCTTC AGGGAATGGG GGTCGTCAGG GAGATAACTG TGACTGTGAT 
GGCTACACAG ACAGCATTTA CACCATCTCT ATCAGCAGTG CCTCCCAGCA AGGCCTGTCA 
CCTTGGTATG CAGAGAAGTG TTCTTCCACA TTGGCTACCT CCTACAGCAG TGGTGATTAC 
ACAGACCAGC GAATAACAAG CGCTGACCTG CACAATGACT GCACAGAGAC CCACACAGGC 
ACCTCGGCTT CAGCACCCCT GGCTGCTGGT ATCTTTGCTC TGGCCTTGGA GGCAAACCCA 
AATCTTACCT GGAGAGATAT GCAGCATCTG GTTGTCTGGA CCTCTGAGTA CGACCCATTG 
GCCAGTAACC CAGGTTGGAA AAAGAATGGG GCAGGCTTGA TGGTGAACAG CCGATTTGGA 
TTTGGCTTGC TAAATGCCAA AGCTCTGGTG GATTTGGCTG ATCCTAGGAC CTGGAGAAAT 
GTGCCTGAGA AGAAAGAATG TGTTGTAAAA GACAATAACT TTGAGCCTAG AGCCCTGAAA 
GCTAATGGAG AAGTAATTGT TGAAATCCCA ACAAGAGCTT GTGAAGGACA AGAAAATGCT 
ATCAAGTCTC TGGAACATGT GCAATTTGAA GCAACAATTG AATATTCTCG TAGAGGAGAC 
CTTCATGTCA CACTCACTTC TGCTGTTGGA ACCAGCACTG TACTGTTGGC TGAAAGGGAA 
AGAGATACAT CCCCCAATGG CTTTAAGAAT TGGGACTTCA TGTCTGTTCA TACATGGGGA 
GAGAATCCTG TAGGCACCTG GACATTGAAA ATTACAGACA TGTCTGGAAG AATGCAAAAT 
GAAGGAAGGA TTGTGAACTG GAAGTTGATT TTGCATGGGA CATCTTCTCA ACCAGAGCAC 
ATGAAGCAGC CTCGTGTGTA CACATCCTAC AATACAGTCC AGAATGACAG GAGAGGAGTG 
GAAAAGATGG TGAATGTTGT GGAGAAGCGG CCCACACAAA AGAGCCTGAA TGGCAATCTC 
CTGGTACCCA AAAACTCCAG CAGCAGCAAT GTGGAGGGTA GAAGGGATGA GCAGGTACAA 
GGAACTCCTT CAAAGGCCAT GCTGCGACTC CTACAAAGTG CTTTTAGCAA GAATGCACTT 
TCAAAACAAT CACCAAAGAA GTCTCCAAGT GCAAAGCTCA GCATCCCTTA TGAAAGTTTC 
TATGAAGCCT TGGAAAAGCT CAACAAGCCC TCCAAGCTTG AAGGCTCTGA AGACAGTCTG 
TACAGTGACT ATGTTGATGT ATTCTATAAC ACAAAACCTT ATAAGCATAG AGATGACAGG 
CTGCTGCAAG CTCTCATGGA CATCCTAAAT GAGGAGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Targeted high-resolution quadrupole-Orbitrap mass spectrometry analyses reveal a significant reduction of tachykinin and opioid neuropeptides level in PC1 and PC2 mutant mouse spinal cords.
Neuropeptides6537-44(2017 Oct)
Saidi M,Beaudry F

Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets.
Development (Cambridge, England)144(13)2402-2414(2017 07)
Sinagoga KL,Stone WJ,Schiesser JV,Schweitzer JI,Sampson L,Zheng Y,Wells JM

Pancreatic ? Cell-Derived Glucagon-Related Peptides Are Required for ? Cell Adaptation and Glucose Homeostasis.
Cell reports18(13)3192-3203(2017 Mar)
Traub S,Meier DT,Schulze F,Dror E,Nordmann TM,Goetz N,Koch N,Dalmas E,Stawiski M,Makshana V,Thorel F,Herrera PL,B?ni-Schnetzler M,Donath MY

Proprotein convertase 1 mediated proneuropeptide proteolytic processing in ischemic neuron injury.
Bratislavske lekarske listy118(10)609-612(2017)
Tang SS,Liang ZY,Guo LR,Zhang JH,Zhou D

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Pcsk1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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