Pax4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pax4
Entrez Gene ID	18506
Full Name	paired box 4
Synonyms	Pax-4
General protein information	Preferred Names paired box 4 Names paired box protein Pax-4 paired box gene 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6 A3.3\|6 11.99 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001159925.1	NP_001153397.1	paired box protein Pax-4 isoform 2
XM_017321450.1	XP_017176939.1	paired box protein Pax-4 isoform X1
NM_001159926.1	NP_001153398.1	paired box protein Pax-4 isoform 3
NM_011038.2	NP_035168.1	paired box protein Pax-4 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PAX4	XP_001151306.1
Bos taurus (cattle)	PAX4	XP_003586045.2
Homo sapiens (human)	PAX4	NP_006184.2
Rattus norvegicus (Norway rat)	Pax4	NP_113987.1
Xenopus tropicalis (tropical clawed frog)	LOC101733204	XP_004913250.1
	PAX4	XP_001090108.2
Canis lupus familiaris (dog)	PAX4	XP_539387.4
Mus musculus (house mouse)	Pax4	NP_035168.1

Gene Ontology
Bibliography

Related articles in PubMed

Ectopic expression of
Druelle N, Vieira A, Shabro A, Courtney M, Mondin M, Rekima S, Napolitano T, Silvano S, Navarro-Sanz S, Hadzic B, Avolio F, Rassoulzadegan M, Schmid HA, Mansouri A, Collombat P
The Journal of cell biology216(12)4299-4311(2017 Dec)

Myofibril breakdown during atrophy is a delayed response requiring the transcription factor PAX4 and desmin depolymerization.
Volodin A, Kosti I, Goldberg AL, Cohen S
Proceedings of the National Academy of Sciences of the United States of America114(8)E1375-E1384(2017 Feb)

The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal ?-cell maturation.
Yang YP, Magnuson MA, Stein R, Wright CV
Development (Cambridge, England)144(2)248-257(2017 01)

Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development.
Churchill AJ, Guti?rrez GD, Singer RA, Lorberbaum DS, Fischer KA, Sussel L
eLife6(2017 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Ectopic expression of Pax4 in pancreatic delta cells results in beta-like cell neogenesis.
Title: Ectopic expression of

The coordinated regulation of distinct cellular pathways particularly related to ER homeostasis by PAX4 not achieved by the mutant variant PAX4R129W alleviates beta cell degeneration and protects against diabetes mellitus.
Title: PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus.

This work establishes the existence of a bona fide PAX4-enriched cell subpopulation nested within pancreatic islets that can expand in periods of increased functional demands, and exhibit improved viability in response to pathophysiological situations.
Title: PAX4 Defines an Expandable ?-Cell Subpopulation in the Adult Pancreatic Islet.

Pax4 expression is not sufficient to transduce pancreatic alpha cells into beta cells. Overexpression of Pax4 in alpha cells may not increase functional beta cell number in diabetic patients
Title: Pax4 Expression does not Transduce Pancreatic Alpha Cells to Beta Cells.

Adult glucagon producing cells can be converted into beta-like cells upon Pax4 misexpression.
Title: Adult duct-lining cells can reprogram into ?-like cells able to counter repeated cycles of toxin-induced diabetes.

The following Pax4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pax4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu15357	NM_001159926.1 Latest version!	Mus musculus paired box 4 (Pax4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu15462	NM_001159925.1 Latest version!	Mus musculus paired box 4 (Pax4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu15432	NM_011038.2 Latest version!	Mus musculus paired box 4 (Pax4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu15432	XM_017321450.1 Latest version!	Mus musculus paired box 4 (Pax4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pax4 ( NM_001159926.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001153398.1 Mus musculus paired box 4 (Pax4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu15357
Clone ID Related Accession (Same CDS sequence)	NM_001159926.1
Accession Version	NM_001159926.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	paired box protein Pax-4 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF031150.2, BC145169.1 and AF145233.1. Transcript Variant: This variant (3) uses alternate in-frame splice sites in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC145169.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849377, SAMN00849378 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGCAGG ACGGACTCAG CAGTGTGAAT CAGCTAGGGG GACTCTTTGT GAATGGCCGG 
CCCCTTCCTC TGGACACCAG GCAGCAGATT GTGCAGCTAG CAATAAGAGG GATGCGACCC 
TGTGACATTT CACGGAGCCT TAAGGTATCT AATGGCTGTG TGAGCAAGAT CCTAGGACGC 
TACTACCGCA CAGGTGTCTT GGAACCCAAG TGTATTGGGG GAAGCAAACC ACGTCTGGCC 
ACACCTGCTG TGGTGGCTCG AATTGCCCAG CTAAAGGATG AGTACCCTGC TCTTTTTGCC 
TGGGAGATCC AACACCAGCT TTGCACTGAA GGGCTTTGTA CCCAGGACAA GGCTCCCAGT 
GTGTCCTCTA TCAATCGAGT ACTTCGGGCA CTTCAGGAAG ACCAGAGCTT GCACTGGACT 
CAACTCAGAT CACCAGCTGT GTTGGCTCCA GTTCTTCCCA GTCCCCACAG TAACTGTGGG 
GCTCCCCGAG GTCCCCACCC AGGAACCAGC CACAGGAATC GGACTATCTT CTCCCCGGGA 
CAAGCCGAGG CACTGGAGAA AGAGTTTCAG CGTGGGCAGT ATCCAGATTC AGTGGCCCGT 
GGGAAGCTGG CTGCTGCCAC CTCTCTGCCT GAAGACACGG TGAGGGTTTG GTTTTCTAAC 
AGAAGAGCCA AATGGCGCAG GCAAGAGAAG CTGAAATGGG AAGCACAGCT GCCAGGGATC 
ATCTCTGCAC AGTCCCCCGG CAGTGTACCC TCAGCTGCCT TGCCTGTGCT GGAACCATTG 
AGTCCTTCCT TCTGTCAGCT ATGCTGTGGG ACAGCACCAG GCAGATGTTC CAGTGACACC 
TCATCCCAGG CCTATCTCCA ACCCTACTGG GACTGCCAAT CCCTCCTTCC TGTGGCTTCC 
TCCTCATATG TGGAATTTGC CTGGCCCTGC CTCACCACCC ATCCTGTGCA TCATCTGATT 
GGAGGCCCAG GACAAGTGCC ATCAACCCAT TGCTCAAACT GGCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153398.1
CDS	264..1271
Translation	MQQDGLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEPKCIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQDKAPSVSSINRVLRALQEDQSLHWTQLRSPAVLAPVLPSPHSNCGAPRGPHPGTSHRNRTIFSPGQAEALEKEFQRGQYPDSVARGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWEAQLPGIISAQSPGSVPSAALPVLEPLSPSFCQLCCGTAPGRCSSDTSSQAYLQPYWDCQSLLPVASSSYVEFAWPCLTTHPVHHLIGGPGQVPSTHCSNWP

Target ORF information:

RefSeq Version	NM_001159926.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus paired box 4 (Pax4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159926.1

ORF Insert Sequence:

ATGCAGCAGG ACGGACTCAG CAGTGTGAAT CAGCTAGGGG GACTCTTTGT GAATGGCCGG 
CCCCTTCCTC TGGACACCAG GCAGCAGATT GTGCAGCTAG CAATAAGAGG GATGCGACCC 
TGTGACATTT CACGGAGCCT TAAGGTATCT AATGGCTGTG TGAGCAAGAT CCTAGGACGC 
TACTACCGCA CAGGTGTCTT GGAACCCAAG TGTATTGGGG GAAGCAAACC ACGTCTGGCC 
ACACCTGCTG TGGTGGCTCG AATTGCCCAG CTAAAGGATG AGTACCCTGC TCTTTTTGCC 
TGGGAGATCC AACACCAGCT TTGCACTGAA GGGCTTTGTA CCCAGGACAA GGCTCCCAGT 
GTGTCCTCTA TCAATCGAGT ACTTCGGGCA CTTCAGGAAG ACCAGAGCTT GCACTGGACT 
CAACTCAGAT CACCAGCTGT GTTGGCTCCA GTTCTTCCCA GTCCCCACAG TAACTGTGGG 
GCTCCCCGAG GTCCCCACCC AGGAACCAGC CACAGGAATC GGACTATCTT CTCCCCGGGA 
CAAGCCGAGG CACTGGAGAA AGAGTTTCAG CGTGGGCAGT ATCCAGATTC AGTGGCCCGT 
GGGAAGCTGG CTGCTGCCAC CTCTCTGCCT GAAGACACGG TGAGGGTTTG GTTTTCTAAC 
AGAAGAGCCA AATGGCGCAG GCAAGAGAAG CTGAAATGGG AAGCACAGCT GCCAGGGATC 
ATCTCTGCAC AGTCCCCCGG CAGTGTACCC TCAGCTGCCT TGCCTGTGCT GGAACCATTG 
AGTCCTTCCT TCTGTCAGCT ATGCTGTGGG ACAGCACCAG GCAGATGTTC CAGTGACACC 
TCATCCCAGG CCTATCTCCA ACCCTACTGG GACTGCCAAT CCCTCCTTCC TGTGGCTTCC 
TCCTCATATG TGGAATTTGC CTGGCCCTGC CTCACCACCC ATCCTGTGCA TCATCTGATT 
GGAGGCCCAG GACAAGTGCC ATCAACCCAT TGCTCAAACT GGCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pax4 ( NM_001159925.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001153397.1 Mus musculus paired box 4 (Pax4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu15462
Clone ID Related Accession (Same CDS sequence)	NM_001159925.1
Accession Version	NM_001159925.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1011bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-23
Organism	Mus musculus(house mouse)
Product	paired box protein Pax-4 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF031150.2, BC145168.1 and AF145233.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC145168.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849377, SAMN00849378 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGCAGG ACGGACTCAG CAGTGTGAAT CAGCTAGGGG GACTCTTTGT GAATGGCCGG 
CCCCTTCCTC TGGACACCAG GCAGCAGATT GTGCAGCTAG CAATAAGAGG GATGCGACCC 
TGTGACATTT CACGGAGCCT TAAGGTATCT AATGGCTGTG TGAGCAAGAT CCTAGGACGC 
TACTACCGCA CAGGTGTCTT GGAACCCAAG TGTATTGGGG GAAGCAAACC ACGTCTGGCC 
ACACCTGCTG TGGTGGCTCG AATTGCCCAG CTAAAGGATG AGTACCCTGC TCTTTTTGCC 
TGGGAGATCC AACACCAGCT TTGCACTGAA GGGCTTTGTA CCCAGGACAA GGCTCCCAGT 
GTGTCCTCTA TCAATCGAGT ACTTCGGGCA CTTCAGGAAG ACCAGAGCTT GCACTGGACT 
CAACTCAGAT CACCAGCTGT GTTGGCTCCA GTTCTTCCCA GTCCCCACAG TAACTGTGGG 
GCTCCCCGAG GTCCCCACCC AGGAACCAGC CACAGGAATC GGACTATCTT CTCCCCGGGA 
CAAGCCGAGG CACTGGAGAA AGAGTTTCAG CGTGGGCAGT ATCCAGATTC AGTGGCCCGT 
GGGAAGCTGG CTGCTGCCAC CTCTCTGCCT GAAGACACGG TGAGGGTTTG GTTTTCTAAC 
AGAAGAGCCA AATGGCGCAG GCAAGAGAAG CTGAAATGGG AAGCACAGCT GCCAGGGATC 
ATCTCTGCAC AGCAGTCCCC CGGCAGTGTA CCCTCAGCTG CCTTGCCTGT GCTGGAACCA 
TTGAGTCCTT CCTTCTGTCA GCTATGCTGT GGGACAGCAC CAGGCAGATG TTCCAGTGAC 
ACCTCATCCC AGGCCTATCT CCAACCCTAC TGGGACTGCC AATCCCTCCT TCCTGTGGCT 
TCCTCCTCAT ATGTGGAATT TGCCTGGCCC TGCCTCACCA CCCATCCTGT GCATCATCTG 
ATTGGAGGCC CAGGACAAGT GCCATCAACC CATTGCTCAA ACTGGCCATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153397.1
CDS	264..1274
Translation	MQQDGLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEPKCIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQDKAPSVSSINRVLRALQEDQSLHWTQLRSPAVLAPVLPSPHSNCGAPRGPHPGTSHRNRTIFSPGQAEALEKEFQRGQYPDSVARGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWEAQLPGIISAQQSPGSVPSAALPVLEPLSPSFCQLCCGTAPGRCSSDTSSQAYLQPYWDCQSLLPVASSSYVEFAWPCLTTHPVHHLIGGPGQVPSTHCSNWP

Target ORF information:

RefSeq Version	NM_001159925.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus paired box 4 (Pax4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159925.1

ORF Insert Sequence:

ATGCAGCAGG ACGGACTCAG CAGTGTGAAT CAGCTAGGGG GACTCTTTGT GAATGGCCGG 
CCCCTTCCTC TGGACACCAG GCAGCAGATT GTGCAGCTAG CAATAAGAGG GATGCGACCC 
TGTGACATTT CACGGAGCCT TAAGGTATCT AATGGCTGTG TGAGCAAGAT CCTAGGACGC 
TACTACCGCA CAGGTGTCTT GGAACCCAAG TGTATTGGGG GAAGCAAACC ACGTCTGGCC 
ACACCTGCTG TGGTGGCTCG AATTGCCCAG CTAAAGGATG AGTACCCTGC TCTTTTTGCC 
TGGGAGATCC AACACCAGCT TTGCACTGAA GGGCTTTGTA CCCAGGACAA GGCTCCCAGT 
GTGTCCTCTA TCAATCGAGT ACTTCGGGCA CTTCAGGAAG ACCAGAGCTT GCACTGGACT 
CAACTCAGAT CACCAGCTGT GTTGGCTCCA GTTCTTCCCA GTCCCCACAG TAACTGTGGG 
GCTCCCCGAG GTCCCCACCC AGGAACCAGC CACAGGAATC GGACTATCTT CTCCCCGGGA 
CAAGCCGAGG CACTGGAGAA AGAGTTTCAG CGTGGGCAGT ATCCAGATTC AGTGGCCCGT 
GGGAAGCTGG CTGCTGCCAC CTCTCTGCCT GAAGACACGG TGAGGGTTTG GTTTTCTAAC 
AGAAGAGCCA AATGGCGCAG GCAAGAGAAG CTGAAATGGG AAGCACAGCT GCCAGGGATC 
ATCTCTGCAC AGCAGTCCCC CGGCAGTGTA CCCTCAGCTG CCTTGCCTGT GCTGGAACCA 
TTGAGTCCTT CCTTCTGTCA GCTATGCTGT GGGACAGCAC CAGGCAGATG TTCCAGTGAC 
ACCTCATCCC AGGCCTATCT CCAACCCTAC TGGGACTGCC AATCCCTCCT TCCTGTGGCT 
TCCTCCTCAT ATGTGGAATT TGCCTGGCCC TGCCTCACCA CCCATCCTGT GCATCATCTG 
ATTGGAGGCC CAGGACAAGT GCCATCAACC CATTGCTCAA ACTGGCCATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pax4 ( NM_011038.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035168.1 Mus musculus paired box 4 (Pax4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu15432
Clone ID Related Accession (Same CDS sequence)	XM_017321450.1 , NM_011038.2
Accession Version	NM_011038.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1050bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	paired box protein Pax-4 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF031150.2 and AF145233.1. On May 7, 2009 this sequence version replaced NM_011038.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF031150.2, AB008912.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGCAGG ACGGACTCAG CAGTGTGAAT CAGCTAGGGG GACTCTTTGT GAATGGCCGG 
CCCCTTCCTC TGGACACCAG GCAGCAGATT GTGCAGCTAG CAATAAGAGG GATGCGACCC 
TGTGACATTT CACGGAGCCT TAAGGTATCT AATGGCTGTG TGAGCAAGAT CCTAGGACGC 
TACTACCGCA CAGGTGTCTT GGAACCCAAG TGTATTGGGG GAAGCAAACC ACGTCTGGCC 
ACACCTGCTG TGGTGGCTCG AATTGCCCAG CTAAAGGATG AGTACCCTGC TCTTTTTGCC 
TGGGAGATCC AACACCAGCT TTGCACTGAA GGGCTTTGTA CCCAGGACAA GGCTCCCAGT 
GTGTCCTCTA TCAATCGAGT ACTTCGGGCA CTTCAGGAAG ACCAGAGCTT GCACTGGACT 
CAACTCAGAT CACCAGCTGT GTTGGCTCCA GTTCTTCCCA GTCCCCACAG TAACTGTGGG 
GCTCCCCGAG GTCCCCACCC AGGAACCAGC CACAGGAATC GGACTATCTT CTCCCCGGGA 
CAAGCCGAGG CACTGGAGAA AGAGTTTCAG CGTGGGCAGT ATCCAGATTC AGTGGCCCGT 
GGGAAGCTGG CTGCTGCCAC CTCTCTGCCT GAAGACACGG TGAGGGTTTG GTTTTCTAAC 
AGAAGAGCCA AATGGCGCAG GCAAGAGAAG CTGAAATGGG AAGCACAGCT GCCAGGTGCT 
TCCCAGGACC TGACAGTACC AAAAAATTCT CCAGGGATCA TCTCTGCACA GCAGTCCCCC 
GGCAGTGTAC CCTCAGCTGC CTTGCCTGTG CTGGAACCAT TGAGTCCTTC CTTCTGTCAG 
CTATGCTGTG GGACAGCACC AGGCAGATGT TCCAGTGACA CCTCATCCCA GGCCTATCTC 
CAACCCTACT GGGACTGCCA ATCCCTCCTT CCTGTGGCTT CCTCCTCATA TGTGGAATTT 
GCCTGGCCCT GCCTCACCAC CCATCCTGTG CATCATCTGA TTGGAGGCCC AGGACAAGTG 
CCATCAACCC ATTGCTCAAA CTGGCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035168.1
CDS	264..1313
Translation	MQQDGLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEPKCIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQDKAPSVSSINRVLRALQEDQSLHWTQLRSPAVLAPVLPSPHSNCGAPRGPHPGTSHRNRTIFSPGQAEALEKEFQRGQYPDSVARGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWEAQLPGASQDLTVPKNSPGIISAQQSPGSVPSAALPVLEPLSPSFCQLCCGTAPGRCSSDTSSQAYLQPYWDCQSLLPVASSSYVEFAWPCLTTHPVHHLIGGPGQVPSTHCSNWP

Target ORF information:

RefSeq Version	NM_011038.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus paired box 4 (Pax4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011038.2

ORF Insert Sequence:

ATGCAGCAGG ACGGACTCAG CAGTGTGAAT CAGCTAGGGG GACTCTTTGT GAATGGCCGG 
CCCCTTCCTC TGGACACCAG GCAGCAGATT GTGCAGCTAG CAATAAGAGG GATGCGACCC 
TGTGACATTT CACGGAGCCT TAAGGTATCT AATGGCTGTG TGAGCAAGAT CCTAGGACGC 
TACTACCGCA CAGGTGTCTT GGAACCCAAG TGTATTGGGG GAAGCAAACC ACGTCTGGCC 
ACACCTGCTG TGGTGGCTCG AATTGCCCAG CTAAAGGATG AGTACCCTGC TCTTTTTGCC 
TGGGAGATCC AACACCAGCT TTGCACTGAA GGGCTTTGTA CCCAGGACAA GGCTCCCAGT 
GTGTCCTCTA TCAATCGAGT ACTTCGGGCA CTTCAGGAAG ACCAGAGCTT GCACTGGACT 
CAACTCAGAT CACCAGCTGT GTTGGCTCCA GTTCTTCCCA GTCCCCACAG TAACTGTGGG 
GCTCCCCGAG GTCCCCACCC AGGAACCAGC CACAGGAATC GGACTATCTT CTCCCCGGGA 
CAAGCCGAGG CACTGGAGAA AGAGTTTCAG CGTGGGCAGT ATCCAGATTC AGTGGCCCGT 
GGGAAGCTGG CTGCTGCCAC CTCTCTGCCT GAAGACACGG TGAGGGTTTG GTTTTCTAAC 
AGAAGAGCCA AATGGCGCAG GCAAGAGAAG CTGAAATGGG AAGCACAGCT GCCAGGTGCT 
TCCCAGGACC TGACAGTACC AAAAAATTCT CCAGGGATCA TCTCTGCACA GCAGTCCCCC 
GGCAGTGTAC CCTCAGCTGC CTTGCCTGTG CTGGAACCAT TGAGTCCTTC CTTCTGTCAG 
CTATGCTGTG GGACAGCACC AGGCAGATGT TCCAGTGACA CCTCATCCCA GGCCTATCTC 
CAACCCTACT GGGACTGCCA ATCCCTCCTT CCTGTGGCTT CCTCCTCATA TGTGGAATTT 
GCCTGGCCCT GCCTCACCAC CCATCCTGTG CATCATCTGA TTGGAGGCCC AGGACAAGTG 
CCATCAACCC ATTGCTCAAA CTGGCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pax4 ( XM_017321450.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017176939.1 Mus musculus paired box 4 (Pax4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu15432
Clone ID Related Accession (Same CDS sequence)	XM_017321450.1 , NM_011038.2
Accession Version	XM_017321450.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1050bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	paired box protein Pax-4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCAGG ACGGACTCAG CAGTGTGAAT CAGCTAGGGG GACTCTTTGT GAATGGCCGG 
CCCCTTCCTC TGGACACCAG GCAGCAGATT GTGCAGCTAG CAATAAGAGG GATGCGACCC 
TGTGACATTT CACGGAGCCT TAAGGTATCT AATGGCTGTG TGAGCAAGAT CCTAGGACGC 
TACTACCGCA CAGGTGTCTT GGAACCCAAG TGTATTGGGG GAAGCAAACC ACGTCTGGCC 
ACACCTGCTG TGGTGGCTCG AATTGCCCAG CTAAAGGATG AGTACCCTGC TCTTTTTGCC 
TGGGAGATCC AACACCAGCT TTGCACTGAA GGGCTTTGTA CCCAGGACAA GGCTCCCAGT 
GTGTCCTCTA TCAATCGAGT ACTTCGGGCA CTTCAGGAAG ACCAGAGCTT GCACTGGACT 
CAACTCAGAT CACCAGCTGT GTTGGCTCCA GTTCTTCCCA GTCCCCACAG TAACTGTGGG 
GCTCCCCGAG GTCCCCACCC AGGAACCAGC CACAGGAATC GGACTATCTT CTCCCCGGGA 
CAAGCCGAGG CACTGGAGAA AGAGTTTCAG CGTGGGCAGT ATCCAGATTC AGTGGCCCGT 
GGGAAGCTGG CTGCTGCCAC CTCTCTGCCT GAAGACACGG TGAGGGTTTG GTTTTCTAAC 
AGAAGAGCCA AATGGCGCAG GCAAGAGAAG CTGAAATGGG AAGCACAGCT GCCAGGTGCT 
TCCCAGGACC TGACAGTACC AAAAAATTCT CCAGGGATCA TCTCTGCACA GCAGTCCCCC 
GGCAGTGTAC CCTCAGCTGC CTTGCCTGTG CTGGAACCAT TGAGTCCTTC CTTCTGTCAG 
CTATGCTGTG GGACAGCACC AGGCAGATGT TCCAGTGACA CCTCATCCCA GGCCTATCTC 
CAACCCTACT GGGACTGCCA ATCCCTCCTT CCTGTGGCTT CCTCCTCATA TGTGGAATTT 
GCCTGGCCCT GCCTCACCAC CCATCCTGTG CATCATCTGA TTGGAGGCCC AGGACAAGTG 
CCATCAACCC ATTGCTCAAA CTGGCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017176939.1
CDS	106..1155
Translation	MQQDGLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEPKCIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQDKAPSVSSINRVLRALQEDQSLHWTQLRSPAVLAPVLPSPHSNCGAPRGPHPGTSHRNRTIFSPGQAEALEKEFQRGQYPDSVARGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWEAQLPGASQDLTVPKNSPGIISAQQSPGSVPSAALPVLEPLSPSFCQLCCGTAPGRCSSDTSSQAYLQPYWDCQSLLPVASSSYVEFAWPCLTTHPVHHLIGGPGQVPSTHCSNWP

Target ORF information:

RefSeq Version	XM_017321450.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus paired box 4 (Pax4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017321450.1

ORF Insert Sequence:

ATGCAGCAGG ACGGACTCAG CAGTGTGAAT CAGCTAGGGG GACTCTTTGT GAATGGCCGG 
CCCCTTCCTC TGGACACCAG GCAGCAGATT GTGCAGCTAG CAATAAGAGG GATGCGACCC 
TGTGACATTT CACGGAGCCT TAAGGTATCT AATGGCTGTG TGAGCAAGAT CCTAGGACGC 
TACTACCGCA CAGGTGTCTT GGAACCCAAG TGTATTGGGG GAAGCAAACC ACGTCTGGCC 
ACACCTGCTG TGGTGGCTCG AATTGCCCAG CTAAAGGATG AGTACCCTGC TCTTTTTGCC 
TGGGAGATCC AACACCAGCT TTGCACTGAA GGGCTTTGTA CCCAGGACAA GGCTCCCAGT 
GTGTCCTCTA TCAATCGAGT ACTTCGGGCA CTTCAGGAAG ACCAGAGCTT GCACTGGACT 
CAACTCAGAT CACCAGCTGT GTTGGCTCCA GTTCTTCCCA GTCCCCACAG TAACTGTGGG 
GCTCCCCGAG GTCCCCACCC AGGAACCAGC CACAGGAATC GGACTATCTT CTCCCCGGGA 
CAAGCCGAGG CACTGGAGAA AGAGTTTCAG CGTGGGCAGT ATCCAGATTC AGTGGCCCGT 
GGGAAGCTGG CTGCTGCCAC CTCTCTGCCT GAAGACACGG TGAGGGTTTG GTTTTCTAAC 
AGAAGAGCCA AATGGCGCAG GCAAGAGAAG CTGAAATGGG AAGCACAGCT GCCAGGTGCT 
TCCCAGGACC TGACAGTACC AAAAAATTCT CCAGGGATCA TCTCTGCACA GCAGTCCCCC 
GGCAGTGTAC CCTCAGCTGC CTTGCCTGTG CTGGAACCAT TGAGTCCTTC CTTCTGTCAG 
CTATGCTGTG GGACAGCACC AGGCAGATGT TCCAGTGACA CCTCATCCCA GGCCTATCTC 
CAACCCTACT GGGACTGCCA ATCCCTCCTT CCTGTGGCTT CCTCCTCATA TGTGGAATTT 
GCCTGGCCCT GCCTCACCAC CCATCCTGTG CATCATCTGA TTGGAGGCCC AGGACAAGTG 
CCATCAACCC ATTGCTCAAA CTGGCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ectopic expression of
The Journal of cell biology216(12)4299-4311(2017 Dec)
Druelle N,Vieira A,Shabro A,Courtney M,Mondin M,Rekima S,Napolitano T,Silvano S,Navarro-Sanz S,Hadzic B,Avolio F,Rassoulzadegan M,Schmid HA,Mansouri A,Collombat P

Myofibril breakdown during atrophy is a delayed response requiring the transcription factor PAX4 and desmin depolymerization.
Proceedings of the National Academy of Sciences of the United States of America114(8)E1375-E1384(2017 Feb)
Volodin A,Kosti I,Goldberg AL,Cohen S

The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal ?-cell maturation.
Development (Cambridge, England)144(2)248-257(2017 01)
Yang YP,Magnuson MA,Stein R,Wright CV

Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development.
eLife6(2017 Jan)
Churchill AJ,Guti?rrez GD,Singer RA,Lorberbaum DS,Fischer KA,Sussel L

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Pax4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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