Oca2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Oca2
Entrez Gene ID	18431
Full Name	oculocutaneous albinism II
Synonyms	D7H15S12,D7Icr28RN,D7Nic1,p,p
General protein information	Preferred Names oculocutaneous albinism II Names P protein Oca2 melanocyte-specific transporter protein pink-eyed dilution protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7 B5\|7 33.44 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_021879.2	NP_068679.1	P protein
XM_006540699.1	XP_006540762.1	P protein isoform X1
XM_006540700.1	XP_006540763.1	P protein isoform X2
NM_021879.3	NP_068679.1	P protein

Pathways from BioSystems

Homologies

	LOC712220	XP_002804735.1
Pan troglodytes (chimpanzee)	OCA2	XP_001162129.1
Mus musculus (house mouse)	Oca2	NP_068679.1
Bos taurus (cattle)	LOC524289	XP_002685246.1
Xenopus tropicalis (tropical clawed frog)	oca2	XP_002937026.2
Danio rerio (zebrafish)	oca2	XP_695807.5
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009283	XP_320079.4
Homo sapiens (human)	OCA2	NP_000266.2
Canis lupus familiaris (dog)	LOC488683	XP_545800.3
Rattus norvegicus (Norway rat)	LOC100365773	NP_001258422.1
Gallus gallus (chicken)	OCA2	XP_425579.4

Gene Ontology
Bibliography

Related articles in PubMed

Beyond Epilepsy and Autism: Disruption of GABRB3 Causes Ocular Hypopigmentation.
Delahanty RJ, Zhang Y, Bichell TJ, Shen W, Verdier K, Macdonald RL, Xu L, Boyd K, Williams J, Kang JQ
Cell reports17(12)3115-3124(2016 12)

The transcription factor TBX2 regulates melanogenesis in melanocytes by repressing Oca2.
Chen Y, Pan L, Su Z, Wang J, Li H, Ma X, Liu Y, Lu F, Qu J, Hou L
Molecular and cellular biochemistry415(1-2)103-9(2016 Apr)

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.
Fairfield H, Srivastava A, Ananda G, Liu R, Kircher M, Lakshminarayana A, Harris BS, Karst SY, Dionne LA, Kane CC, Curtain M, Berry ML, Ward-Bailey PF, Greenstein I, Byers C, Czechanski A, Sharp J, Palmer K, Gudis P, Martin W, Tadenev A, Bogdanik L, Pratt CH, Chang B, Schroeder DG, Cox GA, Cliften P, Milbrandt J, Murray S, Burgess R, Bergstrom DE, Donahue LR, Hamamy H, Masri A, Santoni FA, Makrythanasis P, Antonarakis SE, Shendure J, Reinholdt LG
Genome research25(7)948-57(2015 Jul)

Development of a novel pink-eyed dilution mouse model showing progressive darkening of the eyes and coat hair with aging.
Ishikawa A, Sugiyama M, Hondo E, Kinoshita K, Yamagishi Y
Experimental animals64(2)207-20(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that impairment in GABRB3 downregulates OCA2 and indirectly causes ocular hypopigmentation and visual defects in Angelman syndrome (AS) and Prader-Willi syndrome
Title: Beyond Epilepsy and Autism: Disruption of GABRB3 Causes Ocular Hypopigmentation.

Standard chromatin immunoprecipitation and reporter assays suggest that TBX2 represses Oca2 at least in part directly. Hence, the results suggest that TBX2 may act as a nexus linking cell proliferation and melanogenesis
Title: The transcription factor TBX2 regulates melanogenesis in melanocytes by repressing Oca2.

the inhibition of P-protein can significantly change the melanosomal morphology, types and their respective numbers, and provided a novel strategy for the control of melanin synthesis.
Title: Unrevealing the role of P-protein on melanosome biology and structure, using siRNA-mediated down regulation of OCA2.

Nonsense nucleotide substitution in the oculocutaneous albinism II gene underlies the original pink-eyed dilution allele (Oca2(p)) in mice.
Title: A nonsense nucleotide substitution in the oculocutaneous albinism II gene underlies the original pink-eyed dilution allele (Oca2(p)) in mice.

High-resolution array-CGH in patients with oculocutaneous albinism identifies new deletions of the TYR, OCA2, and SLC45A2 genes and a complex rearrangement of the OCA2 gene.
Title: High-resolution array-CGH in patients with oculocutaneous albinism identifies new deletions of the TYR, OCA2, and SLC45A2 genes and a complex rearrangement of the OCA2 gene.

The following Oca2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Oca2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu12534	NM_021879.3 Latest version!	Mus musculus oculocutaneous albinism II (Oca2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu12534	XM_006540699.1 Latest version!	Mus musculus oculocutaneous albinism II (Oca2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu38723	XM_006540700.1 Latest version!	Mus musculus oculocutaneous albinism II (Oca2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OMu12534	NM_021879.2	Mus musculus oculocutaneous albinism II (Oca2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Oca2 ( NM_021879.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_068679.1 Mus musculus oculocutaneous albinism II (Oca2), mRNA.

Price & Availability↑

CloneID	OMu12534
Clone ID Related Accession (Same CDS sequence)	NM_021879.2 , XM_006540699.1 , NM_021879.3
Accession Version	NM_021879.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2502bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-29
Organism	Mus musculus(house mouse)
Product	P protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC102150.10, AC121900.2, AC102220.8 and AC102299.11. On Nov 17, 2006 this sequence version replaced NM_021879.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC119220.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849379 [ECO:0000348] ##Evidence-Data-END##

ATGCGCCTAG AGAACAAAGA CATCAGGCTG GCCTCAGCCG TGCTGGAAGT AGAGCTACAC 
CAGACATCTG CTTTGTCGGT CCCAACTTGC CCAGACCCAG GACGGCTGCT GACCGTCAAA 
CCTGCTACCA GTAACTACAA GCTGGGCCAG GCAGACCCCT GCATCCCATA TGCTGGCGAG 
GCTGCTGGGA AGAGCGTCTG TGTTCCTGAA CATACAGAGT TTGGCTCATT CCTCGTGAAG 
GGGAGCTCCA GCTTAAAAGA CCTTTCTTTT AAGGAAGACA CTCCTCTGCT CTGGAATTCA 
TCCCAAAAGA AAAGGTCACA GCTCATGCCT GTTCATCACC CAGAATTCAT AGCTACTGAA 
GGTTCCTGGG AAAATGGCCT TACTGCCTGG GAGCAAAAAT GCATGCTGGG TAAAGAGGTT 
GCTGATTTGT CTGCATTGGC CTCCTCAGAG AAACGGGATC TTGCAGGCAG TGTCCATCTT 
AGAGCCCAGG TCTCCAAGCT TGGGTGCTGT GTGCGGTGGA TAAAGATCAC AGGCTTGTTT 
GTTTTCGTGG TGCTCTGCTC TATTTTATTC AGCCTGTATC CGGACCAAGG AAAGTTCTGG 
CAGCTGTTGG CTGTGTCACC GCTGGAAAAC TACTCTGTGA ACCTCAGTGG TCACGCGGAC 
TCCATGATAC TTCAGCTGGA CCTGGCAGGG GCCTTAATGG CTGGAGGACC AAGTGGTTCC 
GGGAAAGAAG AACATGTCGT GGTGGTGGTG ACCCAGACAG ACGCAGCGGG CAACAGACGG 
CGGCGACCAC AGCAGCTCAC CTACAATTGG ACTGTCCTTT TAAATCCAAG AAGTGAGCAC 
GTGGTGGTGA GCAGAACCTT TGAGATAGTG AGCAGGGAGG CTGTTTCCAT CAGCATCCAG 
GCCTCTCTCC AACAGACTCG CCTCGTTCCT CTTTTGCTGG CCCATCAGTT CCTTGGGGCA 
AGCGTTGAAG CACAAGTGGC CAGTGCGGTG GCAATCCTTG CAGGGGTTTA TACTCTGATC 
ATATTTGAGA TTGTTCACAG AACCCTGGCA GCCATGTTGG GAGCACTTGC AGCACTAGCA 
GCCTTGGCTG TGGTTGGAGA TAGACCCAGC CTGACCCACG TGGTGGAGTG GATTGATTTC 
GAGACTCTGG CCCTGCTGTT TGGCATGATG ATCTTAGTAG CCGTATTTTC AGAAACAGGA 
TTTTTTGATT ACTGTGCTGT AAAGGCATAT CAACTTTCTC GAGGAAGAGT GTGGGCCATG 
ATCTTCATGC TTTGTCTCAT GGCTGCCATC CTTTCTGCCT TCTTAGACAA TGTCACTACG 
ATGCTCCTTT TTACCCCTGT CACCATAAGG TTATGTGAAG TGCTCAATCT TGATCCGAGA 
CAAGTCCTCA TTGCAGAAGT GATCTTCACA AACATTGGAG GAGCTGCCAC TGCTATTGGG 
GACCCACCAA ATGTTATCAT TGTTTCCAAT CAGGAGTTGA GAAAAATGGG CCTGGACTTC 
GCTGGTTTCA CAGCACACAT GTTCCTGGGA ATTTGCCTTG TTCTCCTGGT CTCCTTTCCC 
CTCCTCAGAC TTCTGTACTG GAACAAAAAG CTTTATAACA AGGAGCCTAG TGAGATCGTC 
GAACTGAAGC ATGAGATTCA TGTCTGGCGT TTGACTGCCC AGCGCATCAG TCCAGCCAGC 
CGTGAGGAGA CAGCTGTGCG TGGCTTGCTG CTGGAGAAAG TGCTTGCCCT GGAGCATCTG 
CTGGCTCAAA GGTTGCACAC TTTCCACAGG CAAATTTCAC AGGAAGACAA AAATTGGGAG 
ACCAATATTC AAGAGCTACA AAGAAAGCAC AGGATTTCAG ACAGGAGTCT GCTTGTCAAG 
TGCCTGACGG TGCTGGGATT TGTCATCTCC ATGTTCTTTC TCAACTCCTT TGTCCCTGGC 
ATTCATCTTG ATCTTGGATG GATTGCTATT CTGGGTGCCA TCTGGTTGCT AATTTTAGCT 
GATATTCATG ACTTTGAGAT CATTCTACAC AGAGTAGAGT GGGCGACTCT TCTCTTCTTT 
GCAGCACTCT TTGTGCTGAT GGAGGCATTG ACACATCTTC ACTTAGTAGA GTATGTTGGA 
GAACAGACTG CCCTACTAAT AAAGATGGTT CCAGAAGATC AGCGCTTTGC AGCTGCCATT 
GTCCTGATAG TGTGGGTCTC AGCCTTGGCA TCATCCTTGA TTGACAACAT CCCATTTACT 
GCTACGATGA TTCCTGTACT CCTGAACCTG AGCCAAGACC CTGAAATTAG TTTGCCTGCA 
CTGCCTCTCA TGTATGCCCT GGCCCTCGGT GCCTGCCTGG GAGGTAATGG GACACTTATC 
GGAGCATCCA CAAATGTTGT TTGTGCAGGA ATCGCAGAGA AGCATGGGTA TGGATTCTCT 
TTCATGGAAT TTTTCAGGTT GGGCTTCCCT GTGATGCTCA TGTCCTGCAC CATTGGGATG 
TGCTATCTCC TGATTGCTCA CATTGTGGTG GGATGGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068679.1
CDS	131..2632
Translation	MRLENKDIRLASAVLEVELHQTSALSVPTCPDPGRLLTVKPATSNYKLGQADPCIPYAGEAAGKSVCVPEHTEFGSFLVKGSSSLKDLSFKEDTPLLWNSSQKKRSQLMPVHHPEFIATEGSWENGLTAWEQKCMLGKEVADLSALASSEKRDLAGSVHLRAQVSKLGCCVRWIKITGLFVFVVLCSILFSLYPDQGKFWQLLAVSPLENYSVNLSGHADSMILQLDLAGALMAGGPSGSGKEEHVVVVVTQTDAAGNRRRRPQQLTYNWTVLLNPRSEHVVVSRTFEIVSREAVSISIQASLQQTRLVPLLLAHQFLGASVEAQVASAVAILAGVYTLIIFEIVHRTLAAMLGALAALAALAVVGDRPSLTHVVEWIDFETLALLFGMMILVAVFSETGFFDYCAVKAYQLSRGRVWAMIFMLCLMAAILSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQELRKMGLDFAGFTAHMFLGICLVLLVSFPLLRLLYWNKKLYNKEPSEIVELKHEIHVWRLTAQRISPASREETAVRGLLLEKVLALEHLLAQRLHTFHRQISQEDKNWETNIQELQRKHRISDRSLLVKCLTVLGFVISMFFLNSFVPGIHLDLGWIAILGAIWLLILADIHDFEIILHRVEWATLLFFAALFVLMEALTHLHLVEYVGEQTALLIKMVPEDQRFAAAIVLIVWVSALASSLIDNIPFTATMIPVLLNLSQDPEISLPALPLMYALALGACLGGNGTLIGASTNVVCAGIAEKHGYGFSFMEFFRLGFPVMLMSCTIGMCYLLIAHIVVGWN

Target ORF information:

RefSeq Version	NM_021879.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus oculocutaneous albinism II (Oca2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021879.2

ORF Insert Sequence:

ATGCGCCTAG AGAACAAAGA CATCAGGCTG GCCTCAGCCG TGCTGGAAGT AGAGCTACAC 
CAGACATCTG CTTTGTCGGT CCCAACTTGC CCAGACCCAG GACGGCTGCT GACCGTCAAA 
CCTGCTACCA GTAACTACAA GCTGGGCCAG GCAGACCCCT GCATCCCATA TGCTGGCGAG 
GCTGCTGGGA AGAGCGTCTG TGTTCCTGAA CATACAGAGT TTGGCTCATT CCTCGTGAAG 
GGGAGCTCCA GCTTAAAAGA CCTTTCTTTT AAGGAAGACA CTCCTCTGCT CTGGAATTCA 
TCCCAAAAGA AAAGGTCACA GCTCATGCCT GTTCATCACC CAGAATTCAT AGCTACTGAA 
GGTTCCTGGG AAAATGGCCT TACTGCCTGG GAGCAAAAAT GCATGCTGGG TAAAGAGGTT 
GCTGATTTGT CTGCATTGGC CTCCTCAGAG AAACGGGATC TTGCAGGCAG TGTCCATCTT 
AGAGCCCAGG TCTCCAAGCT TGGGTGCTGT GTGCGGTGGA TAAAGATCAC AGGCTTGTTT 
GTTTTCGTGG TGCTCTGCTC TATTTTATTC AGCCTGTATC CGGACCAAGG AAAGTTCTGG 
CAGCTGTTGG CTGTGTCACC GCTGGAAAAC TACTCTGTGA ACCTCAGTGG TCACGCGGAC 
TCCATGATAC TTCAGCTGGA CCTGGCAGGG GCCTTAATGG CTGGAGGACC AAGTGGTTCC 
GGGAAAGAAG AACATGTCGT GGTGGTGGTG ACCCAGACAG ACGCAGCGGG CAACAGACGG 
CGGCGACCAC AGCAGCTCAC CTACAATTGG ACTGTCCTTT TAAATCCAAG AAGTGAGCAC 
GTGGTGGTGA GCAGAACCTT TGAGATAGTG AGCAGGGAGG CTGTTTCCAT CAGCATCCAG 
GCCTCTCTCC AACAGACTCG CCTCGTTCCT CTTTTGCTGG CCCATCAGTT CCTTGGGGCA 
AGCGTTGAAG CACAAGTGGC CAGTGCGGTG GCAATCCTTG CAGGGGTTTA TACTCTGATC 
ATATTTGAGA TTGTTCACAG AACCCTGGCA GCCATGTTGG GAGCACTTGC AGCACTAGCA 
GCCTTGGCTG TGGTTGGAGA TAGACCCAGC CTGACCCACG TGGTGGAGTG GATTGATTTC 
GAGACTCTGG CCCTGCTGTT TGGCATGATG ATCTTAGTAG CCGTATTTTC AGAAACAGGA 
TTTTTTGATT ACTGTGCTGT AAAGGCATAT CAACTTTCTC GAGGAAGAGT GTGGGCCATG 
ATCTTCATGC TTTGTCTCAT GGCTGCCATC CTTTCTGCCT TCTTAGACAA TGTCACTACG 
ATGCTCCTTT TTACCCCTGT CACCATAAGG TTATGTGAAG TGCTCAATCT TGATCCGAGA 
CAAGTCCTCA TTGCAGAAGT GATCTTCACA AACATTGGAG GAGCTGCCAC TGCTATTGGG 
GACCCACCAA ATGTTATCAT TGTTTCCAAT CAGGAGTTGA GAAAAATGGG CCTGGACTTC 
GCTGGTTTCA CAGCACACAT GTTCCTGGGA ATTTGCCTTG TTCTCCTGGT CTCCTTTCCC 
CTCCTCAGAC TTCTGTACTG GAACAAAAAG CTTTATAACA AGGAGCCTAG TGAGATCGTC 
GAACTGAAGC ATGAGATTCA TGTCTGGCGT TTGACTGCCC AGCGCATCAG TCCAGCCAGC 
CGTGAGGAGA CAGCTGTGCG TGGCTTGCTG CTGGAGAAAG TGCTTGCCCT GGAGCATCTG 
CTGGCTCAAA GGTTGCACAC TTTCCACAGG CAAATTTCAC AGGAAGACAA AAATTGGGAG 
ACCAATATTC AAGAGCTACA AAGAAAGCAC AGGATTTCAG ACAGGAGTCT GCTTGTCAAG 
TGCCTGACGG TGCTGGGATT TGTCATCTCC ATGTTCTTTC TCAACTCCTT TGTCCCTGGC 
ATTCATCTTG ATCTTGGATG GATTGCTATT CTGGGTGCCA TCTGGTTGCT AATTTTAGCT 
GATATTCATG ACTTTGAGAT CATTCTACAC AGAGTAGAGT GGGCGACTCT TCTCTTCTTT 
GCAGCACTCT TTGTGCTGAT GGAGGCATTG ACACATCTTC ACTTAGTAGA GTATGTTGGA 
GAACAGACTG CCCTACTAAT AAAGATGGTT CCAGAAGATC AGCGCTTTGC AGCTGCCATT 
GTCCTGATAG TGTGGGTCTC AGCCTTGGCA TCATCCTTGA TTGACAACAT CCCATTTACT 
GCTACGATGA TTCCTGTACT CCTGAACCTG AGCCAAGACC CTGAAATTAG TTTGCCTGCA 
CTGCCTCTCA TGTATGCCCT GGCCCTCGGT GCCTGCCTGG GAGGTAATGG GACACTTATC 
GGAGCATCCA CAAATGTTGT TTGTGCAGGA ATCGCAGAGA AGCATGGGTA TGGATTCTCT 
TTCATGGAAT TTTTCAGGTT GGGCTTCCCT GTGATGCTCA TGTCCTGCAC CATTGGGATG 
TGCTATCTCC TGATTGCTCA CATTGTGGTG GGATGGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Oca2 ( NM_021879.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_068679.1 Mus musculus oculocutaneous albinism II (Oca2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu12534
Clone ID Related Accession (Same CDS sequence)	NM_021879.2 , XM_006540699.1 , NM_021879.3
Accession Version	NM_021879.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2502bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Mus musculus(house mouse)
Product	P protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC102150.10, AC121900.2, AC102220.8 and AC102299.11. On Jun 3, 2018 this sequence version replaced NM_021879.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC119220.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849379 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGCCTAG AGAACAAAGA CATCAGGCTG GCCTCAGCCG TGCTGGAAGT AGAGCTACAC 
CAGACATCTG CTTTGTCGGT CCCAACTTGC CCAGACCCAG GACGGCTGCT GACCGTCAAA 
CCTGCTACCA GTAACTACAA GCTGGGCCAG GCAGACCCCT GCATCCCATA TGCTGGCGAG 
GCTGCTGGGA AGAGCGTCTG TGTTCCTGAA CATACAGAGT TTGGCTCATT CCTCGTGAAG 
GGGAGCTCCA GCTTAAAAGA CCTTTCTTTT AAGGAAGACA CTCCTCTGCT CTGGAATTCA 
TCCCAAAAGA AAAGGTCACA GCTCATGCCT GTTCATCACC CAGAATTCAT AGCTACTGAA 
GGTTCCTGGG AAAATGGCCT TACTGCCTGG GAGCAAAAAT GCATGCTGGG TAAAGAGGTT 
GCTGATTTGT CTGCATTGGC CTCCTCAGAG AAACGGGATC TTGCAGGCAG TGTCCATCTT 
AGAGCCCAGG TCTCCAAGCT TGGGTGCTGT GTGCGGTGGA TAAAGATCAC AGGCTTGTTT 
GTTTTCGTGG TGCTCTGCTC TATTTTATTC AGCCTGTATC CGGACCAAGG AAAGTTCTGG 
CAGCTGTTGG CTGTGTCACC GCTGGAAAAC TACTCTGTGA ACCTCAGTGG TCACGCGGAC 
TCCATGATAC TTCAGCTGGA CCTGGCAGGG GCCTTAATGG CTGGAGGACC AAGTGGTTCC 
GGGAAAGAAG AACATGTCGT GGTGGTGGTG ACCCAGACAG ACGCAGCGGG CAACAGACGG 
CGGCGACCAC AGCAGCTCAC CTACAATTGG ACTGTCCTTT TAAATCCAAG AAGTGAGCAC 
GTGGTGGTGA GCAGAACCTT TGAGATAGTG AGCAGGGAGG CTGTTTCCAT CAGCATCCAG 
GCCTCTCTCC AACAGACTCG CCTCGTTCCT CTTTTGCTGG CCCATCAGTT CCTTGGGGCA 
AGCGTTGAAG CACAAGTGGC CAGTGCGGTG GCAATCCTTG CAGGGGTTTA TACTCTGATC 
ATATTTGAGA TTGTTCACAG AACCCTGGCA GCCATGTTGG GAGCACTTGC AGCACTAGCA 
GCCTTGGCTG TGGTTGGAGA TAGACCCAGC CTGACCCACG TGGTGGAGTG GATTGATTTC 
GAGACTCTGG CCCTGCTGTT TGGCATGATG ATCTTAGTAG CCGTATTTTC AGAAACAGGA 
TTTTTTGATT ACTGTGCTGT AAAGGCATAT CAACTTTCTC GAGGAAGAGT GTGGGCCATG 
ATCTTCATGC TTTGTCTCAT GGCTGCCATC CTTTCTGCCT TCTTAGACAA TGTCACTACG 
ATGCTCCTTT TTACCCCTGT CACCATAAGG TTATGTGAAG TGCTCAATCT TGATCCGAGA 
CAAGTCCTCA TTGCAGAAGT GATCTTCACA AACATTGGAG GAGCTGCCAC TGCTATTGGG 
GACCCACCAA ATGTTATCAT TGTTTCCAAT CAGGAGTTGA GAAAAATGGG CCTGGACTTC 
GCTGGTTTCA CAGCACACAT GTTCCTGGGA ATTTGCCTTG TTCTCCTGGT CTCCTTTCCC 
CTCCTCAGAC TTCTGTACTG GAACAAAAAG CTTTATAACA AGGAGCCTAG TGAGATCGTC 
GAACTGAAGC ATGAGATTCA TGTCTGGCGT TTGACTGCCC AGCGCATCAG TCCAGCCAGC 
CGTGAGGAGA CAGCTGTGCG TGGCTTGCTG CTGGAGAAAG TGCTTGCCCT GGAGCATCTG 
CTGGCTCAAA GGTTGCACAC TTTCCACAGG CAAATTTCAC AGGAAGACAA AAATTGGGAG 
ACCAATATTC AAGAGCTACA AAGAAAGCAC AGGATTTCAG ACAGGAGTCT GCTTGTCAAG 
TGCCTGACGG TGCTGGGATT TGTCATCTCC ATGTTCTTTC TCAACTCCTT TGTCCCTGGC 
ATTCATCTTG ATCTTGGATG GATTGCTATT CTGGGTGCCA TCTGGTTGCT AATTTTAGCT 
GATATTCATG ACTTTGAGAT CATTCTACAC AGAGTAGAGT GGGCGACTCT TCTCTTCTTT 
GCAGCACTCT TTGTGCTGAT GGAGGCATTG ACACATCTTC ACTTAGTAGA GTATGTTGGA 
GAACAGACTG CCCTACTAAT AAAGATGGTT CCAGAAGATC AGCGCTTTGC AGCTGCCATT 
GTCCTGATAG TGTGGGTCTC AGCCTTGGCA TCATCCTTGA TTGACAACAT CCCATTTACT 
GCTACGATGA TTCCTGTACT CCTGAACCTG AGCCAAGACC CTGAAATTAG TTTGCCTGCA 
CTGCCTCTCA TGTATGCCCT GGCCCTCGGT GCCTGCCTGG GAGGTAATGG GACACTTATC 
GGAGCATCCA CAAATGTTGT TTGTGCAGGA ATCGCAGAGA AGCATGGGTA TGGATTCTCT 
TTCATGGAAT TTTTCAGGTT GGGCTTCCCT GTGATGCTCA TGTCCTGCAC CATTGGGATG 
TGCTATCTCC TGATTGCTCA CATTGTGGTG GGATGGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068679.1
CDS	143..2644
Translation	MRLENKDIRLASAVLEVELHQTSALSVPTCPDPGRLLTVKPATSNYKLGQADPCIPYAGEAAGKSVCVPEHTEFGSFLVKGSSSLKDLSFKEDTPLLWNSSQKKRSQLMPVHHPEFIATEGSWENGLTAWEQKCMLGKEVADLSALASSEKRDLAGSVHLRAQVSKLGCCVRWIKITGLFVFVVLCSILFSLYPDQGKFWQLLAVSPLENYSVNLSGHADSMILQLDLAGALMAGGPSGSGKEEHVVVVVTQTDAAGNRRRRPQQLTYNWTVLLNPRSEHVVVSRTFEIVSREAVSISIQASLQQTRLVPLLLAHQFLGASVEAQVASAVAILAGVYTLIIFEIVHRTLAAMLGALAALAALAVVGDRPSLTHVVEWIDFETLALLFGMMILVAVFSETGFFDYCAVKAYQLSRGRVWAMIFMLCLMAAILSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQELRKMGLDFAGFTAHMFLGICLVLLVSFPLLRLLYWNKKLYNKEPSEIVELKHEIHVWRLTAQRISPASREETAVRGLLLEKVLALEHLLAQRLHTFHRQISQEDKNWETNIQELQRKHRISDRSLLVKCLTVLGFVISMFFLNSFVPGIHLDLGWIAILGAIWLLILADIHDFEIILHRVEWATLLFFAALFVLMEALTHLHLVEYVGEQTALLIKMVPEDQRFAAAIVLIVWVSALASSLIDNIPFTATMIPVLLNLSQDPEISLPALPLMYALALGACLGGNGTLIGASTNVVCAGIAEKHGYGFSFMEFFRLGFPVMLMSCTIGMCYLLIAHIVVGWN

Target ORF information:

RefSeq Version	NM_021879.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus oculocutaneous albinism II (Oca2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021879.3

ORF Insert Sequence:

ATGCGCCTAG AGAACAAAGA CATCAGGCTG GCCTCAGCCG TGCTGGAAGT AGAGCTACAC 
CAGACATCTG CTTTGTCGGT CCCAACTTGC CCAGACCCAG GACGGCTGCT GACCGTCAAA 
CCTGCTACCA GTAACTACAA GCTGGGCCAG GCAGACCCCT GCATCCCATA TGCTGGCGAG 
GCTGCTGGGA AGAGCGTCTG TGTTCCTGAA CATACAGAGT TTGGCTCATT CCTCGTGAAG 
GGGAGCTCCA GCTTAAAAGA CCTTTCTTTT AAGGAAGACA CTCCTCTGCT CTGGAATTCA 
TCCCAAAAGA AAAGGTCACA GCTCATGCCT GTTCATCACC CAGAATTCAT AGCTACTGAA 
GGTTCCTGGG AAAATGGCCT TACTGCCTGG GAGCAAAAAT GCATGCTGGG TAAAGAGGTT 
GCTGATTTGT CTGCATTGGC CTCCTCAGAG AAACGGGATC TTGCAGGCAG TGTCCATCTT 
AGAGCCCAGG TCTCCAAGCT TGGGTGCTGT GTGCGGTGGA TAAAGATCAC AGGCTTGTTT 
GTTTTCGTGG TGCTCTGCTC TATTTTATTC AGCCTGTATC CGGACCAAGG AAAGTTCTGG 
CAGCTGTTGG CTGTGTCACC GCTGGAAAAC TACTCTGTGA ACCTCAGTGG TCACGCGGAC 
TCCATGATAC TTCAGCTGGA CCTGGCAGGG GCCTTAATGG CTGGAGGACC AAGTGGTTCC 
GGGAAAGAAG AACATGTCGT GGTGGTGGTG ACCCAGACAG ACGCAGCGGG CAACAGACGG 
CGGCGACCAC AGCAGCTCAC CTACAATTGG ACTGTCCTTT TAAATCCAAG AAGTGAGCAC 
GTGGTGGTGA GCAGAACCTT TGAGATAGTG AGCAGGGAGG CTGTTTCCAT CAGCATCCAG 
GCCTCTCTCC AACAGACTCG CCTCGTTCCT CTTTTGCTGG CCCATCAGTT CCTTGGGGCA 
AGCGTTGAAG CACAAGTGGC CAGTGCGGTG GCAATCCTTG CAGGGGTTTA TACTCTGATC 
ATATTTGAGA TTGTTCACAG AACCCTGGCA GCCATGTTGG GAGCACTTGC AGCACTAGCA 
GCCTTGGCTG TGGTTGGAGA TAGACCCAGC CTGACCCACG TGGTGGAGTG GATTGATTTC 
GAGACTCTGG CCCTGCTGTT TGGCATGATG ATCTTAGTAG CCGTATTTTC AGAAACAGGA 
TTTTTTGATT ACTGTGCTGT AAAGGCATAT CAACTTTCTC GAGGAAGAGT GTGGGCCATG 
ATCTTCATGC TTTGTCTCAT GGCTGCCATC CTTTCTGCCT TCTTAGACAA TGTCACTACG 
ATGCTCCTTT TTACCCCTGT CACCATAAGG TTATGTGAAG TGCTCAATCT TGATCCGAGA 
CAAGTCCTCA TTGCAGAAGT GATCTTCACA AACATTGGAG GAGCTGCCAC TGCTATTGGG 
GACCCACCAA ATGTTATCAT TGTTTCCAAT CAGGAGTTGA GAAAAATGGG CCTGGACTTC 
GCTGGTTTCA CAGCACACAT GTTCCTGGGA ATTTGCCTTG TTCTCCTGGT CTCCTTTCCC 
CTCCTCAGAC TTCTGTACTG GAACAAAAAG CTTTATAACA AGGAGCCTAG TGAGATCGTC 
GAACTGAAGC ATGAGATTCA TGTCTGGCGT TTGACTGCCC AGCGCATCAG TCCAGCCAGC 
CGTGAGGAGA CAGCTGTGCG TGGCTTGCTG CTGGAGAAAG TGCTTGCCCT GGAGCATCTG 
CTGGCTCAAA GGTTGCACAC TTTCCACAGG CAAATTTCAC AGGAAGACAA AAATTGGGAG 
ACCAATATTC AAGAGCTACA AAGAAAGCAC AGGATTTCAG ACAGGAGTCT GCTTGTCAAG 
TGCCTGACGG TGCTGGGATT TGTCATCTCC ATGTTCTTTC TCAACTCCTT TGTCCCTGGC 
ATTCATCTTG ATCTTGGATG GATTGCTATT CTGGGTGCCA TCTGGTTGCT AATTTTAGCT 
GATATTCATG ACTTTGAGAT CATTCTACAC AGAGTAGAGT GGGCGACTCT TCTCTTCTTT 
GCAGCACTCT TTGTGCTGAT GGAGGCATTG ACACATCTTC ACTTAGTAGA GTATGTTGGA 
GAACAGACTG CCCTACTAAT AAAGATGGTT CCAGAAGATC AGCGCTTTGC AGCTGCCATT 
GTCCTGATAG TGTGGGTCTC AGCCTTGGCA TCATCCTTGA TTGACAACAT CCCATTTACT 
GCTACGATGA TTCCTGTACT CCTGAACCTG AGCCAAGACC CTGAAATTAG TTTGCCTGCA 
CTGCCTCTCA TGTATGCCCT GGCCCTCGGT GCCTGCCTGG GAGGTAATGG GACACTTATC 
GGAGCATCCA CAAATGTTGT TTGTGCAGGA ATCGCAGAGA AGCATGGGTA TGGATTCTCT 
TTCATGGAAT TTTTCAGGTT GGGCTTCCCT GTGATGCTCA TGTCCTGCAC CATTGGGATG 
TGCTATCTCC TGATTGCTCA CATTGTGGTG GGATGGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Oca2 ( XM_006540699.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006540762.1 Mus musculus oculocutaneous albinism II (Oca2), transcript variant X1, mRNA.

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CloneID	OMu12534
Clone ID Related Accession (Same CDS sequence)	NM_021879.2 , XM_006540699.1 , NM_021879.3
Accession Version	XM_006540699.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2502bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	P protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGCCTAG AGAACAAAGA CATCAGGCTG GCCTCAGCCG TGCTGGAAGT AGAGCTACAC 
CAGACATCTG CTTTGTCGGT CCCAACTTGC CCAGACCCAG GACGGCTGCT GACCGTCAAA 
CCTGCTACCA GTAACTACAA GCTGGGCCAG GCAGACCCCT GCATCCCATA TGCTGGCGAG 
GCTGCTGGGA AGAGCGTCTG TGTTCCTGAA CATACAGAGT TTGGCTCATT CCTCGTGAAG 
GGGAGCTCCA GCTTAAAAGA CCTTTCTTTT AAGGAAGACA CTCCTCTGCT CTGGAATTCA 
TCCCAAAAGA AAAGGTCACA GCTCATGCCT GTTCATCACC CAGAATTCAT AGCTACTGAA 
GGTTCCTGGG AAAATGGCCT TACTGCCTGG GAGCAAAAAT GCATGCTGGG TAAAGAGGTT 
GCTGATTTGT CTGCATTGGC CTCCTCAGAG AAACGGGATC TTGCAGGCAG TGTCCATCTT 
AGAGCCCAGG TCTCCAAGCT TGGGTGCTGT GTGCGGTGGA TAAAGATCAC AGGCTTGTTT 
GTTTTCGTGG TGCTCTGCTC TATTTTATTC AGCCTGTATC CGGACCAAGG AAAGTTCTGG 
CAGCTGTTGG CTGTGTCACC GCTGGAAAAC TACTCTGTGA ACCTCAGTGG TCACGCGGAC 
TCCATGATAC TTCAGCTGGA CCTGGCAGGG GCCTTAATGG CTGGAGGACC AAGTGGTTCC 
GGGAAAGAAG AACATGTCGT GGTGGTGGTG ACCCAGACAG ACGCAGCGGG CAACAGACGG 
CGGCGACCAC AGCAGCTCAC CTACAATTGG ACTGTCCTTT TAAATCCAAG AAGTGAGCAC 
GTGGTGGTGA GCAGAACCTT TGAGATAGTG AGCAGGGAGG CTGTTTCCAT CAGCATCCAG 
GCCTCTCTCC AACAGACTCG CCTCGTTCCT CTTTTGCTGG CCCATCAGTT CCTTGGGGCA 
AGCGTTGAAG CACAAGTGGC CAGTGCGGTG GCAATCCTTG CAGGGGTTTA TACTCTGATC 
ATATTTGAGA TTGTTCACAG AACCCTGGCA GCCATGTTGG GAGCACTTGC AGCACTAGCA 
GCCTTGGCTG TGGTTGGAGA TAGACCCAGC CTGACCCACG TGGTGGAGTG GATTGATTTC 
GAGACTCTGG CCCTGCTGTT TGGCATGATG ATCTTAGTAG CCGTATTTTC AGAAACAGGA 
TTTTTTGATT ACTGTGCTGT AAAGGCATAT CAACTTTCTC GAGGAAGAGT GTGGGCCATG 
ATCTTCATGC TTTGTCTCAT GGCTGCCATC CTTTCTGCCT TCTTAGACAA TGTCACTACG 
ATGCTCCTTT TTACCCCTGT CACCATAAGG TTATGTGAAG TGCTCAATCT TGATCCGAGA 
CAAGTCCTCA TTGCAGAAGT GATCTTCACA AACATTGGAG GAGCTGCCAC TGCTATTGGG 
GACCCACCAA ATGTTATCAT TGTTTCCAAT CAGGAGTTGA GAAAAATGGG CCTGGACTTC 
GCTGGTTTCA CAGCACACAT GTTCCTGGGA ATTTGCCTTG TTCTCCTGGT CTCCTTTCCC 
CTCCTCAGAC TTCTGTACTG GAACAAAAAG CTTTATAACA AGGAGCCTAG TGAGATCGTC 
GAACTGAAGC ATGAGATTCA TGTCTGGCGT TTGACTGCCC AGCGCATCAG TCCAGCCAGC 
CGTGAGGAGA CAGCTGTGCG TGGCTTGCTG CTGGAGAAAG TGCTTGCCCT GGAGCATCTG 
CTGGCTCAAA GGTTGCACAC TTTCCACAGG CAAATTTCAC AGGAAGACAA AAATTGGGAG 
ACCAATATTC AAGAGCTACA AAGAAAGCAC AGGATTTCAG ACAGGAGTCT GCTTGTCAAG 
TGCCTGACGG TGCTGGGATT TGTCATCTCC ATGTTCTTTC TCAACTCCTT TGTCCCTGGC 
ATTCATCTTG ATCTTGGATG GATTGCTATT CTGGGTGCCA TCTGGTTGCT AATTTTAGCT 
GATATTCATG ACTTTGAGAT CATTCTACAC AGAGTAGAGT GGGCGACTCT TCTCTTCTTT 
GCAGCACTCT TTGTGCTGAT GGAGGCATTG ACACATCTTC ACTTAGTAGA GTATGTTGGA 
GAACAGACTG CCCTACTAAT AAAGATGGTT CCAGAAGATC AGCGCTTTGC AGCTGCCATT 
GTCCTGATAG TGTGGGTCTC AGCCTTGGCA TCATCCTTGA TTGACAACAT CCCATTTACT 
GCTACGATGA TTCCTGTACT CCTGAACCTG AGCCAAGACC CTGAAATTAG TTTGCCTGCA 
CTGCCTCTCA TGTATGCCCT GGCCCTCGGT GCCTGCCTGG GAGGTAATGG GACACTTATC 
GGAGCATCCA CAAATGTTGT TTGTGCAGGA ATCGCAGAGA AGCATGGGTA TGGATTCTCT 
TTCATGGAAT TTTTCAGGTT GGGCTTCCCT GTGATGCTCA TGTCCTGCAC CATTGGGATG 
TGCTATCTCC TGATTGCTCA CATTGTGGTG GGATGGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006540762.1
CDS	305..2806
Translation	MRLENKDIRLASAVLEVELHQTSALSVPTCPDPGRLLTVKPATSNYKLGQADPCIPYAGEAAGKSVCVPEHTEFGSFLVKGSSSLKDLSFKEDTPLLWNSSQKKRSQLMPVHHPEFIATEGSWENGLTAWEQKCMLGKEVADLSALASSEKRDLAGSVHLRAQVSKLGCCVRWIKITGLFVFVVLCSILFSLYPDQGKFWQLLAVSPLENYSVNLSGHADSMILQLDLAGALMAGGPSGSGKEEHVVVVVTQTDAAGNRRRRPQQLTYNWTVLLNPRSEHVVVSRTFEIVSREAVSISIQASLQQTRLVPLLLAHQFLGASVEAQVASAVAILAGVYTLIIFEIVHRTLAAMLGALAALAALAVVGDRPSLTHVVEWIDFETLALLFGMMILVAVFSETGFFDYCAVKAYQLSRGRVWAMIFMLCLMAAILSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQELRKMGLDFAGFTAHMFLGICLVLLVSFPLLRLLYWNKKLYNKEPSEIVELKHEIHVWRLTAQRISPASREETAVRGLLLEKVLALEHLLAQRLHTFHRQISQEDKNWETNIQELQRKHRISDRSLLVKCLTVLGFVISMFFLNSFVPGIHLDLGWIAILGAIWLLILADIHDFEIILHRVEWATLLFFAALFVLMEALTHLHLVEYVGEQTALLIKMVPEDQRFAAAIVLIVWVSALASSLIDNIPFTATMIPVLLNLSQDPEISLPALPLMYALALGACLGGNGTLIGASTNVVCAGIAEKHGYGFSFMEFFRLGFPVMLMSCTIGMCYLLIAHIVVGWN

Target ORF information:

RefSeq Version	XM_006540699.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus oculocutaneous albinism II (Oca2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006540699.1

ORF Insert Sequence:

ATGCGCCTAG AGAACAAAGA CATCAGGCTG GCCTCAGCCG TGCTGGAAGT AGAGCTACAC 
CAGACATCTG CTTTGTCGGT CCCAACTTGC CCAGACCCAG GACGGCTGCT GACCGTCAAA 
CCTGCTACCA GTAACTACAA GCTGGGCCAG GCAGACCCCT GCATCCCATA TGCTGGCGAG 
GCTGCTGGGA AGAGCGTCTG TGTTCCTGAA CATACAGAGT TTGGCTCATT CCTCGTGAAG 
GGGAGCTCCA GCTTAAAAGA CCTTTCTTTT AAGGAAGACA CTCCTCTGCT CTGGAATTCA 
TCCCAAAAGA AAAGGTCACA GCTCATGCCT GTTCATCACC CAGAATTCAT AGCTACTGAA 
GGTTCCTGGG AAAATGGCCT TACTGCCTGG GAGCAAAAAT GCATGCTGGG TAAAGAGGTT 
GCTGATTTGT CTGCATTGGC CTCCTCAGAG AAACGGGATC TTGCAGGCAG TGTCCATCTT 
AGAGCCCAGG TCTCCAAGCT TGGGTGCTGT GTGCGGTGGA TAAAGATCAC AGGCTTGTTT 
GTTTTCGTGG TGCTCTGCTC TATTTTATTC AGCCTGTATC CGGACCAAGG AAAGTTCTGG 
CAGCTGTTGG CTGTGTCACC GCTGGAAAAC TACTCTGTGA ACCTCAGTGG TCACGCGGAC 
TCCATGATAC TTCAGCTGGA CCTGGCAGGG GCCTTAATGG CTGGAGGACC AAGTGGTTCC 
GGGAAAGAAG AACATGTCGT GGTGGTGGTG ACCCAGACAG ACGCAGCGGG CAACAGACGG 
CGGCGACCAC AGCAGCTCAC CTACAATTGG ACTGTCCTTT TAAATCCAAG AAGTGAGCAC 
GTGGTGGTGA GCAGAACCTT TGAGATAGTG AGCAGGGAGG CTGTTTCCAT CAGCATCCAG 
GCCTCTCTCC AACAGACTCG CCTCGTTCCT CTTTTGCTGG CCCATCAGTT CCTTGGGGCA 
AGCGTTGAAG CACAAGTGGC CAGTGCGGTG GCAATCCTTG CAGGGGTTTA TACTCTGATC 
ATATTTGAGA TTGTTCACAG AACCCTGGCA GCCATGTTGG GAGCACTTGC AGCACTAGCA 
GCCTTGGCTG TGGTTGGAGA TAGACCCAGC CTGACCCACG TGGTGGAGTG GATTGATTTC 
GAGACTCTGG CCCTGCTGTT TGGCATGATG ATCTTAGTAG CCGTATTTTC AGAAACAGGA 
TTTTTTGATT ACTGTGCTGT AAAGGCATAT CAACTTTCTC GAGGAAGAGT GTGGGCCATG 
ATCTTCATGC TTTGTCTCAT GGCTGCCATC CTTTCTGCCT TCTTAGACAA TGTCACTACG 
ATGCTCCTTT TTACCCCTGT CACCATAAGG TTATGTGAAG TGCTCAATCT TGATCCGAGA 
CAAGTCCTCA TTGCAGAAGT GATCTTCACA AACATTGGAG GAGCTGCCAC TGCTATTGGG 
GACCCACCAA ATGTTATCAT TGTTTCCAAT CAGGAGTTGA GAAAAATGGG CCTGGACTTC 
GCTGGTTTCA CAGCACACAT GTTCCTGGGA ATTTGCCTTG TTCTCCTGGT CTCCTTTCCC 
CTCCTCAGAC TTCTGTACTG GAACAAAAAG CTTTATAACA AGGAGCCTAG TGAGATCGTC 
GAACTGAAGC ATGAGATTCA TGTCTGGCGT TTGACTGCCC AGCGCATCAG TCCAGCCAGC 
CGTGAGGAGA CAGCTGTGCG TGGCTTGCTG CTGGAGAAAG TGCTTGCCCT GGAGCATCTG 
CTGGCTCAAA GGTTGCACAC TTTCCACAGG CAAATTTCAC AGGAAGACAA AAATTGGGAG 
ACCAATATTC AAGAGCTACA AAGAAAGCAC AGGATTTCAG ACAGGAGTCT GCTTGTCAAG 
TGCCTGACGG TGCTGGGATT TGTCATCTCC ATGTTCTTTC TCAACTCCTT TGTCCCTGGC 
ATTCATCTTG ATCTTGGATG GATTGCTATT CTGGGTGCCA TCTGGTTGCT AATTTTAGCT 
GATATTCATG ACTTTGAGAT CATTCTACAC AGAGTAGAGT GGGCGACTCT TCTCTTCTTT 
GCAGCACTCT TTGTGCTGAT GGAGGCATTG ACACATCTTC ACTTAGTAGA GTATGTTGGA 
GAACAGACTG CCCTACTAAT AAAGATGGTT CCAGAAGATC AGCGCTTTGC AGCTGCCATT 
GTCCTGATAG TGTGGGTCTC AGCCTTGGCA TCATCCTTGA TTGACAACAT CCCATTTACT 
GCTACGATGA TTCCTGTACT CCTGAACCTG AGCCAAGACC CTGAAATTAG TTTGCCTGCA 
CTGCCTCTCA TGTATGCCCT GGCCCTCGGT GCCTGCCTGG GAGGTAATGG GACACTTATC 
GGAGCATCCA CAAATGTTGT TTGTGCAGGA ATCGCAGAGA AGCATGGGTA TGGATTCTCT 
TTCATGGAAT TTTTCAGGTT GGGCTTCCCT GTGATGCTCA TGTCCTGCAC CATTGGGATG 
TGCTATCTCC TGATTGCTCA CATTGTGGTG GGATGGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Oca2 ( XM_006540700.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006540763.1 Mus musculus oculocutaneous albinism II (Oca2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu38723
Clone ID Related Accession (Same CDS sequence)	XM_006540700.1
Accession Version	XM_006540700.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2472bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	P protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGCCTAG AGAACAAAGA CATCAGGCTG GCCTCAGCCG TGCTGGAAGT AGAGCTACAC 
CAGACATCTG CTTTGTCGGT CCCAACTTGC CCAGACCCAG GACGGCTGCT GACCGTCAAA 
CCTGCTACCA GTAACTACAA GCTGGGCCAG GCAGACCCCT GCATCCCATA TGCTGGCGAG 
GCTGCTGGGA AGAGCGTCTG TGTTCCTGAA CATACAGAGT TTGGCTCATT CCTCGTGAAG 
GGGAGCTCCA GCTTAAAAGA CCTTTCTTTT AAGGAAGACA CTCCTCTGCT CTGGAATTCA 
TCCCAAAAGA AAAGGTCACA GCTCATGCCT GTTCATCACC CAGAATTCAT AGCTACTGAA 
GGTTCCTGGG AAAATGGCCT TACTGCCTGG GAGCAAAAAT GCATGCTGGG TAAAGAGGTT 
GCTGATTTGT CTGCATTGGC CTCCTCAGAG AAACGGGATC TTGCAGGCAG TGTCCATCTT 
AGAGCCCAGG TCTCCAAGCT TGGGTGCTGT GTGCGGTGGA TAAAGATCAC AGGCTTGTTT 
GTTTTCGTGG TGCTCTGCTC TATTTTATTC AGCCTGTATC CGGACCAAGG AAAGTTCTGG 
CAGCTGTTGG CTGTGTCACC GCTGGAAAAC TACTCTGTGA ACCTCAGTGG TCACGCGGAC 
TCCATGATAC TTCAGCTGGA CCTGGCAGGG GCCTTAATGG CTGGAGGACC AAGTGGTTCC 
GGGAAAGAAG AACATGTCGT GGTGGTGGTG ACCCAGACAG ACGCAGCGGG CAACAGACGG 
CGGCGACCAC AGCAGCTCAC CTACAATTGG ACTGTCCTTT TAAATCCAAG AAGTGAGCAC 
GTGGTGGTGA GCAGAACCTT TGAGATAGTG AGCAGGGAGG CTGTTTCCAT CAGCATCCAG 
GCCTCTCTCC AACAGACTCG CCTCGTTCCT CTTTTGCTGG CCCATCAGTT CCTTGGGGCA 
AGCGTTGAAG CACAAGTGGC CAGTGCGGTG GCAATCCTTG CAGGGGTTTA TACTCTGATC 
ATATTTGAGA TTGTTCACAG AACCCTGGCA GCCATGTTGG GAGCACTTGC AGCACTAGCA 
GCCTTGGCTG TGGTTGGAGA TAGACCCAGC CTGACCCACG TGGTGGAGTG GATTGATTTC 
GAGACTCTGG CCCTGCTGTT TGGCATGATG ATCTTAGTAG CCGTATTTTC AGAAACAGGA 
TTTTTTGATT ACTGTGCTGT AAAGGCATAT CAACTTTCTC GAGGAAGAGT GTGGGCCATG 
ATCTTCATGC TTTGTCTCAT GGCTGCCATC CTTTCTGCCT TCTTAGACAA TGTCACTACG 
ATGCTCCTTT TTACCCCTGT CACCATAAGG TTATGTGAAG TGCTCAATCT TGATCCGAGA 
CAAGTCCTCA TTGCAGAAGT GATCTTCACA AACATTGGAG GAGCTGCCAC TGCTATTGGG 
GACCCACCAA ATGTTATCAT TGTTTCCAAT CAGGAGTTGA GAAAAATGGG CCTGGACTTC 
GCTGGTTTCA CAGCACACAT GTTCCTGGGA ATTTGCCTTG TTCTCCTGGT CTCCTTTCCC 
CTCCTCAGAC TTCTGTACTG GAACAAAAAG CTTTATAACA AGGAGCCTAG TGAGATCGTC 
GAACTGAAGC ATGAGATTCA TGTCTGGCGT TTGACTGCCC AGCGCATCAG TCCAGCCAGC 
CGTGAGGAGA CAGCTGTGCG TGGCTTGCTG CTGGAGAAAG TGCTTGCCCT GGAGCATCTG 
CTGGCTCAAA GGTTGCACAC TTTCCACAGG CAAATTTCAC AGGAAGACAA AAATTGGGAG 
ACCAATATTC AAGAGCTACA AAGAAAGCAC AGGATTTCAG ACAGGAGTCT GCTTGTCAAG 
TGCCTGACGG TGCTGGGATT TGTCATCTCC ATGTTCTTTC TCAACTCCTT TGTCCCTGGC 
ATTCATCTTG ATCTTGGATG GATTGCTATT CTGGGTGCCA TCTGGTTGCT AATTTTAGCT 
GATATTCATG ACTTTGAGAT CATTCTACAC AGAGTAGAGT GGGCGACTCT TCTCTTCTTT 
GCAGCACTCT TTGTGCTGAT GGAGGCATTG ACACATCTTC ACTTAGTAGA GTATGTTGGA 
GAACAGACTG CCCTACTAAT AAAGATGGTT CCAGAAGATC AGCGCTTTGC AGCTGCCATT 
GTCCTGATAG TGTGGGTCTC AGCCTTGGCA TCATCCTTGA TTGACAACAT CCCATTTACT 
GCTACGATGA TTCCTGTACT CCTGAACCTG AGCCAAGACC CTGAAATTAG TTTGCCTGCA 
CTGCCTCTCA TGTATGCCCT GGCCCTCGGT GCCTGCCTGG GAGGTAATGG GACACTTATC 
GGAGCATCCA CAAATGTTGT TTGTGCAGGA ATCGCAGAGA AGCATGGGTT GGGCTTCCCT 
GTGATGCTCA TGTCCTGCAC CATTGGGATG TGCTATCTCC TGATTGCTCA CATTGTGGTG 
GGATGGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006540763.1
CDS	309..2780
Translation	MRLENKDIRLASAVLEVELHQTSALSVPTCPDPGRLLTVKPATSNYKLGQADPCIPYAGEAAGKSVCVPEHTEFGSFLVKGSSSLKDLSFKEDTPLLWNSSQKKRSQLMPVHHPEFIATEGSWENGLTAWEQKCMLGKEVADLSALASSEKRDLAGSVHLRAQVSKLGCCVRWIKITGLFVFVVLCSILFSLYPDQGKFWQLLAVSPLENYSVNLSGHADSMILQLDLAGALMAGGPSGSGKEEHVVVVVTQTDAAGNRRRRPQQLTYNWTVLLNPRSEHVVVSRTFEIVSREAVSISIQASLQQTRLVPLLLAHQFLGASVEAQVASAVAILAGVYTLIIFEIVHRTLAAMLGALAALAALAVVGDRPSLTHVVEWIDFETLALLFGMMILVAVFSETGFFDYCAVKAYQLSRGRVWAMIFMLCLMAAILSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQELRKMGLDFAGFTAHMFLGICLVLLVSFPLLRLLYWNKKLYNKEPSEIVELKHEIHVWRLTAQRISPASREETAVRGLLLEKVLALEHLLAQRLHTFHRQISQEDKNWETNIQELQRKHRISDRSLLVKCLTVLGFVISMFFLNSFVPGIHLDLGWIAILGAIWLLILADIHDFEIILHRVEWATLLFFAALFVLMEALTHLHLVEYVGEQTALLIKMVPEDQRFAAAIVLIVWVSALASSLIDNIPFTATMIPVLLNLSQDPEISLPALPLMYALALGACLGGNGTLIGASTNVVCAGIAEKHGLGFPVMLMSCTIGMCYLLIAHIVVGWN

Target ORF information:

RefSeq Version	XM_006540700.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus oculocutaneous albinism II (Oca2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006540700.1

ORF Insert Sequence:

ATGCGCCTAG AGAACAAAGA CATCAGGCTG GCCTCAGCCG TGCTGGAAGT AGAGCTACAC 
CAGACATCTG CTTTGTCGGT CCCAACTTGC CCAGACCCAG GACGGCTGCT GACCGTCAAA 
CCTGCTACCA GTAACTACAA GCTGGGCCAG GCAGACCCCT GCATCCCATA TGCTGGCGAG 
GCTGCTGGGA AGAGCGTCTG TGTTCCTGAA CATACAGAGT TTGGCTCATT CCTCGTGAAG 
GGGAGCTCCA GCTTAAAAGA CCTTTCTTTT AAGGAAGACA CTCCTCTGCT CTGGAATTCA 
TCCCAAAAGA AAAGGTCACA GCTCATGCCT GTTCATCACC CAGAATTCAT AGCTACTGAA 
GGTTCCTGGG AAAATGGCCT TACTGCCTGG GAGCAAAAAT GCATGCTGGG TAAAGAGGTT 
GCTGATTTGT CTGCATTGGC CTCCTCAGAG AAACGGGATC TTGCAGGCAG TGTCCATCTT 
AGAGCCCAGG TCTCCAAGCT TGGGTGCTGT GTGCGGTGGA TAAAGATCAC AGGCTTGTTT 
GTTTTCGTGG TGCTCTGCTC TATTTTATTC AGCCTGTATC CGGACCAAGG AAAGTTCTGG 
CAGCTGTTGG CTGTGTCACC GCTGGAAAAC TACTCTGTGA ACCTCAGTGG TCACGCGGAC 
TCCATGATAC TTCAGCTGGA CCTGGCAGGG GCCTTAATGG CTGGAGGACC AAGTGGTTCC 
GGGAAAGAAG AACATGTCGT GGTGGTGGTG ACCCAGACAG ACGCAGCGGG CAACAGACGG 
CGGCGACCAC AGCAGCTCAC CTACAATTGG ACTGTCCTTT TAAATCCAAG AAGTGAGCAC 
GTGGTGGTGA GCAGAACCTT TGAGATAGTG AGCAGGGAGG CTGTTTCCAT CAGCATCCAG 
GCCTCTCTCC AACAGACTCG CCTCGTTCCT CTTTTGCTGG CCCATCAGTT CCTTGGGGCA 
AGCGTTGAAG CACAAGTGGC CAGTGCGGTG GCAATCCTTG CAGGGGTTTA TACTCTGATC 
ATATTTGAGA TTGTTCACAG AACCCTGGCA GCCATGTTGG GAGCACTTGC AGCACTAGCA 
GCCTTGGCTG TGGTTGGAGA TAGACCCAGC CTGACCCACG TGGTGGAGTG GATTGATTTC 
GAGACTCTGG CCCTGCTGTT TGGCATGATG ATCTTAGTAG CCGTATTTTC AGAAACAGGA 
TTTTTTGATT ACTGTGCTGT AAAGGCATAT CAACTTTCTC GAGGAAGAGT GTGGGCCATG 
ATCTTCATGC TTTGTCTCAT GGCTGCCATC CTTTCTGCCT TCTTAGACAA TGTCACTACG 
ATGCTCCTTT TTACCCCTGT CACCATAAGG TTATGTGAAG TGCTCAATCT TGATCCGAGA 
CAAGTCCTCA TTGCAGAAGT GATCTTCACA AACATTGGAG GAGCTGCCAC TGCTATTGGG 
GACCCACCAA ATGTTATCAT TGTTTCCAAT CAGGAGTTGA GAAAAATGGG CCTGGACTTC 
GCTGGTTTCA CAGCACACAT GTTCCTGGGA ATTTGCCTTG TTCTCCTGGT CTCCTTTCCC 
CTCCTCAGAC TTCTGTACTG GAACAAAAAG CTTTATAACA AGGAGCCTAG TGAGATCGTC 
GAACTGAAGC ATGAGATTCA TGTCTGGCGT TTGACTGCCC AGCGCATCAG TCCAGCCAGC 
CGTGAGGAGA CAGCTGTGCG TGGCTTGCTG CTGGAGAAAG TGCTTGCCCT GGAGCATCTG 
CTGGCTCAAA GGTTGCACAC TTTCCACAGG CAAATTTCAC AGGAAGACAA AAATTGGGAG 
ACCAATATTC AAGAGCTACA AAGAAAGCAC AGGATTTCAG ACAGGAGTCT GCTTGTCAAG 
TGCCTGACGG TGCTGGGATT TGTCATCTCC ATGTTCTTTC TCAACTCCTT TGTCCCTGGC 
ATTCATCTTG ATCTTGGATG GATTGCTATT CTGGGTGCCA TCTGGTTGCT AATTTTAGCT 
GATATTCATG ACTTTGAGAT CATTCTACAC AGAGTAGAGT GGGCGACTCT TCTCTTCTTT 
GCAGCACTCT TTGTGCTGAT GGAGGCATTG ACACATCTTC ACTTAGTAGA GTATGTTGGA 
GAACAGACTG CCCTACTAAT AAAGATGGTT CCAGAAGATC AGCGCTTTGC AGCTGCCATT 
GTCCTGATAG TGTGGGTCTC AGCCTTGGCA TCATCCTTGA TTGACAACAT CCCATTTACT 
GCTACGATGA TTCCTGTACT CCTGAACCTG AGCCAAGACC CTGAAATTAG TTTGCCTGCA 
CTGCCTCTCA TGTATGCCCT GGCCCTCGGT GCCTGCCTGG GAGGTAATGG GACACTTATC 
GGAGCATCCA CAAATGTTGT TTGTGCAGGA ATCGCAGAGA AGCATGGGTT GGGCTTCCCT 
GTGATGCTCA TGTCCTGCAC CATTGGGATG TGCTATCTCC TGATTGCTCA CATTGTGGTG 
GGATGGAATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Beyond Epilepsy and Autism: Disruption of GABRB3 Causes Ocular Hypopigmentation.
Cell reports17(12)3115-3124(2016 12)
Delahanty RJ,Zhang Y,Bichell TJ,Shen W,Verdier K,Macdonald RL,Xu L,Boyd K,Williams J,Kang JQ

The transcription factor TBX2 regulates melanogenesis in melanocytes by repressing Oca2.
Molecular and cellular biochemistry415(1-2)103-9(2016 Apr)
Chen Y,Pan L,Su Z,Wang J,Li H,Ma X,Liu Y,Lu F,Qu J,Hou L

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.
Genome research25(7)948-57(2015 Jul)
Fairfield H,Srivastava A,Ananda G,Liu R,Kircher M,Lakshminarayana A,Harris BS,Karst SY,Dionne LA,Kane CC,Curtain M,Berry ML,Ward-Bailey PF,Greenstein I,Byers C,Czechanski A,Sharp J,Palmer K,Gudis P,Martin W,Tadenev A,Bogdanik L,Pratt CH,Chang B,Schroeder DG,Cox GA,Cliften P,Milbrandt J,Murray S,Burgess R,Bergstrom DE,Donahue LR,Hamamy H,Masri A,Santoni FA,Makrythanasis P,Antonarakis SE,Shendure J,Reinholdt LG

Development of a novel pink-eyed dilution mouse model showing progressive darkening of the eyes and coat hair with aging.
Experimental animals64(2)207-20(2015)
Ishikawa A,Sugiyama M,Hondo E,Kinoshita K,Yamagishi Y

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Oca2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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