Fxyd5 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fxyd5
Entrez Gene ID	18301
Full Name	FXYD domain-containing ion transport regulator 5
Synonyms	EF-8,Oit2,RIC
General protein information	Preferred Names FXYD domain-containing ion transport regulator 5 Names FXYD domain-containing ion transport regulator 5 dysadherin ion channel homolog RIC oncoprotein induced transcript 2 oncoprotein-induced protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 B1
Summary	This gene encodes a precursor protein that is member of the FXYD family of transmembrane glycoproteins. Like most members of the FXYD family, the encoded protein is a subunit of the sodium-potassium adenosine triphosphatase pump. FXYD family members have tissue-specific expression and differentially regulate the activity of this pump. The protein encoded by this gene also plays a role in cell adhesion and motility. The orthologous human protein inhibits epithelial cadherin, a calcium-dependent adhesion protein and is associated with cancer (promotes metastasis). Alternative splicing of this mouse gene results in multiple transcript variants. [provided by RefSeq, Dec 2013].

mRNA and Protein(s)

mRNA	Protein	Name
NM_008761.4	NP_032787.1	FXYD domain-containing ion transport regulator 5 isoform a precursor
NM_001111073.2	NP_001104543.1	FXYD domain-containing ion transport regulator 5 isoform a precursor
NM_001287217.1	NP_001274146.1	FXYD domain-containing ion transport regulator 5 isoform b precursor
NM_001287213.1	NP_001274142.1	FXYD domain-containing ion transport regulator 5 isoform a precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	FXYD5	NP_001178992.1
Pan troglodytes (chimpanzee)	FXYD5	XP_001158330.1
Canis lupus familiaris (dog)	FXYD5	XP_005616778.1
Mus musculus (house mouse)	Fxyd5	NP_001274146.1
	LOC718467	XP_001111193.1
Homo sapiens (human)	FXYD5	NP_001158077.1
Canis lupus familiaris (dog)	LOC102156583	XP_005642142.1
Rattus norvegicus (Norway rat)	Fxyd5	NP_068709.2

Gene Ontology
Bibliography

Related articles in PubMed

FXYD5 (dysadherin) may mediate metastatic progression through regulation of the ?-Na
Lubarski-Gotliv I, Dey K, Kuznetsov Y, Kalchenco V, Asher C, Garty H
American journal of physiology. Cell physiology313(1)C108-C117(2017 Jul)

FXYD5 Protein Has a Pro-inflammatory Role in Epithelial Cells.
Lubarski-Gotliv I, Asher C, Dada LA, Garty H
The Journal of biological chemistry291(21)11072-82(2016 May)

Modulation of cell polarization by the Na+-K+-ATPase-associated protein FXYD5 (dysadherin).
Lubarski I, Asher C, Garty H
American journal of physiology. Cell physiology306(11)C1080-8(2014 Jun)

FXYD5 (dysadherin) regulates the paracellular permeability in cultured kidney collecting duct cells.
Lubarski I, Asher C, Garty H
American journal of physiology. Renal physiology301(6)F1270-80(2011 Dec)

Dysadherin can enhance tumorigenesis by conferring properties of stem-like cells to hepatocellular carcinoma cells.
Park JR, Kim RJ, Lee YK, Kim SR, Roh KJ, Oh SH, Kong G, Kang KS, Nam JS
Journal of hepatology54(1)122-31(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

FXYD5 mediates metastatic progression through regulation of the beta Na(+)-K(+)-ATPase subunit in the 4T1 mouse breast cancer model.
Title: FXYD5 (dysadherin) may mediate metastatic progression through regulation of the ?-Na

transfection of M1 epithelial cell line with FXYD5 largely increases lipopolysaccharide (LPS) stimulated CCL2 mRNA and secretion of the translated protein
Title: FXYD5 Protein Has a Pro-inflammatory Role in Epithelial Cells.

FXYD5 affects cell polarization through its interaction with Na(+)-K(+)-ATPase.
Title: Modulation of cell polarization by the Na+-K+-ATPase-associated protein FXYD5 (dysadherin).

Expressing FXYD5 in mouse kidney collecting duct cell line M1 led to a large decrease in amiloride-insensitive transepithelial electrical resistance as well as increased permeability to 4-kDa dextran.
Title: FXYD5 (dysadherin) regulates the paracellular permeability in cultured kidney collecting duct cells.

FXYD5 is significantly increased in the lungs and nasal epithelium of cystic fibrosis mice as assessed by RT-PCR.
Title: FXYD5 modulates Na+ absorption and is increased in cystic fibrosis airway epithelia.

The following Fxyd5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fxyd5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu02726	NM_001287213.1 Latest version!	Mus musculus FXYD domain-containing ion transport regulator 5 (Fxyd5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu02726	NM_008761.4 Latest version!	Mus musculus FXYD domain-containing ion transport regulator 5 (Fxyd5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu02726	NM_001111073.2 Latest version!	Mus musculus FXYD domain-containing ion transport regulator 5 (Fxyd5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu16846	NM_001287217.1 Latest version!	Mus musculus FXYD domain-containing ion transport regulator 5 (Fxyd5), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fxyd5 ( NM_008761.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032787.1 Mus musculus FXYD domain-containing ion transport regulator 5 (Fxyd5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu02726
Clone ID Related Accession (Same CDS sequence)	NM_008761.4 , NM_001111073.2 , NM_001287213.1
Accession Version	NM_008761.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	FXYD domain-containing ion transport regulator 5 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Kathleen Sweadner. The reference sequence was derived from AI121044.1, AC149055.6, AK003068.1 and BY574553.1. On Dec 10, 2013 this sequence version replaced NM_008761.3. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DT909989.1, CF617162.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCACTGT CCAGTCGCCT GTGTCTCCTC ACTATTGTCG CCCTGATTCT GCCCAGCAGA 
GGGCAGACAC CAAAAAAGCC CACATCCATT TTTACAGCGG ACCAGACTTC TGCGACTACT 
CGTGACAATG TCCCAGATCC AGATCAAACC AGCCCAGGAG TCCAGACCAC CCCTCTCATC 
TGGACCAGAG AAGAAGCCAC AGGAAGCCAG ACAGCAGCCC AAACCGAGAC CCAGCAACTG 
ACAAAAATGG CCACCTCGAA TCCAGTGTCA GATCCAGGGC CACATACAAG CAGCAAGAAA 
GGTACCCCTG CAGTCTCCAG GATCGAGCCT CTCAGCCCAT CCAAAAACTT CATGCCTCCA 
TCCTACATTG AACATCCACT GGATTCGAAT GAGAACAACC CCTTCTACTA CGATGATACT 
ACCCTCCGGA AACGGGGACT GCTGGTGGCT GCGGTGCTGT TCATCACGGG AATTATCATT 
CTCACTAGTG GGAAGTGTAG GCAGTTGTCT CAATTTTGCC TGAATCGCCA CAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032787.1
CDS	243..779
Translation	MSLSSRLCLLTIVALILPSRGQTPKKPTSIFTADQTSATTRDNVPDPDQTSPGVQTTPLIWTREEATGSQTAAQTETQQLTKMATSNPVSDPGPHTSSKKGTPAVSRIEPLSPSKNFMPPSYIEHPLDSNENNPFYYDDTTLRKRGLLVAAVLFITGIIILTSGKCRQLSQFCLNRHR

Target ORF information:

RefSeq Version	NM_008761.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus FXYD domain-containing ion transport regulator 5 (Fxyd5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008761.4

ORF Insert Sequence:

ATGTCACTGT CCAGTCGCCT GTGTCTCCTC ACTATTGTCG CCCTGATTCT GCCCAGCAGA 
GGGCAGACAC CAAAAAAGCC CACATCCATT TTTACAGCGG ACCAGACTTC TGCGACTACT 
CGTGACAATG TCCCAGATCC AGATCAAACC AGCCCAGGAG TCCAGACCAC CCCTCTCATC 
TGGACCAGAG AAGAAGCCAC AGGAAGCCAG ACAGCAGCCC AAACCGAGAC CCAGCAACTG 
ACAAAAATGG CCACCTCGAA TCCAGTGTCA GATCCAGGGC CACATACAAG CAGCAAGAAA 
GGTACCCCTG CAGTCTCCAG GATCGAGCCT CTCAGCCCAT CCAAAAACTT CATGCCTCCA 
TCCTACATTG AACATCCACT GGATTCGAAT GAGAACAACC CCTTCTACTA CGATGATACT 
ACCCTCCGGA AACGGGGACT GCTGGTGGCT GCGGTGCTGT TCATCACGGG AATTATCATT 
CTCACTAGTG GGAAGTGTAG GCAGTTGTCT CAATTTTGCC TGAATCGCCA CAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fxyd5 ( NM_001111073.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001104543.1 Mus musculus FXYD domain-containing ion transport regulator 5 (Fxyd5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu02726
Clone ID Related Accession (Same CDS sequence)	NM_008761.4 , NM_001111073.2 , NM_001287213.1
Accession Version	NM_001111073.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	FXYD domain-containing ion transport regulator 5 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC149055.6, AK155763.1 and BY574553.1. On Dec 10, 2013 this sequence version replaced NM_001111073.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK155763.1, BI649641.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN00849383 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCACTGT CCAGTCGCCT GTGTCTCCTC ACTATTGTCG CCCTGATTCT GCCCAGCAGA 
GGGCAGACAC CAAAAAAGCC CACATCCATT TTTACAGCGG ACCAGACTTC TGCGACTACT 
CGTGACAATG TCCCAGATCC AGATCAAACC AGCCCAGGAG TCCAGACCAC CCCTCTCATC 
TGGACCAGAG AAGAAGCCAC AGGAAGCCAG ACAGCAGCCC AAACCGAGAC CCAGCAACTG 
ACAAAAATGG CCACCTCGAA TCCAGTGTCA GATCCAGGGC CACATACAAG CAGCAAGAAA 
GGTACCCCTG CAGTCTCCAG GATCGAGCCT CTCAGCCCAT CCAAAAACTT CATGCCTCCA 
TCCTACATTG AACATCCACT GGATTCGAAT GAGAACAACC CCTTCTACTA CGATGATACT 
ACCCTCCGGA AACGGGGACT GCTGGTGGCT GCGGTGCTGT TCATCACGGG AATTATCATT 
CTCACTAGTG GGAAGTGTAG GCAGTTGTCT CAATTTTGCC TGAATCGCCA CAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001104543.1
CDS	383..919
Translation	MSLSSRLCLLTIVALILPSRGQTPKKPTSIFTADQTSATTRDNVPDPDQTSPGVQTTPLIWTREEATGSQTAAQTETQQLTKMATSNPVSDPGPHTSSKKGTPAVSRIEPLSPSKNFMPPSYIEHPLDSNENNPFYYDDTTLRKRGLLVAAVLFITGIIILTSGKCRQLSQFCLNRHR

Target ORF information:

RefSeq Version	NM_001111073.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus FXYD domain-containing ion transport regulator 5 (Fxyd5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001111073.2

ORF Insert Sequence:

ATGTCACTGT CCAGTCGCCT GTGTCTCCTC ACTATTGTCG CCCTGATTCT GCCCAGCAGA 
GGGCAGACAC CAAAAAAGCC CACATCCATT TTTACAGCGG ACCAGACTTC TGCGACTACT 
CGTGACAATG TCCCAGATCC AGATCAAACC AGCCCAGGAG TCCAGACCAC CCCTCTCATC 
TGGACCAGAG AAGAAGCCAC AGGAAGCCAG ACAGCAGCCC AAACCGAGAC CCAGCAACTG 
ACAAAAATGG CCACCTCGAA TCCAGTGTCA GATCCAGGGC CACATACAAG CAGCAAGAAA 
GGTACCCCTG CAGTCTCCAG GATCGAGCCT CTCAGCCCAT CCAAAAACTT CATGCCTCCA 
TCCTACATTG AACATCCACT GGATTCGAAT GAGAACAACC CCTTCTACTA CGATGATACT 
ACCCTCCGGA AACGGGGACT GCTGGTGGCT GCGGTGCTGT TCATCACGGG AATTATCATT 
CTCACTAGTG GGAAGTGTAG GCAGTTGTCT CAATTTTGCC TGAATCGCCA CAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fxyd5 ( NM_001287213.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001274142.1 Mus musculus FXYD domain-containing ion transport regulator 5 (Fxyd5), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu02726
Clone ID Related Accession (Same CDS sequence)	NM_008761.4 , NM_001111073.2 , NM_001287213.1
Accession Version	NM_001287213.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	FXYD domain-containing ion transport regulator 5 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC149055.6. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CB597630.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCACTGT CCAGTCGCCT GTGTCTCCTC ACTATTGTCG CCCTGATTCT GCCCAGCAGA 
GGGCAGACAC CAAAAAAGCC CACATCCATT TTTACAGCGG ACCAGACTTC TGCGACTACT 
CGTGACAATG TCCCAGATCC AGATCAAACC AGCCCAGGAG TCCAGACCAC CCCTCTCATC 
TGGACCAGAG AAGAAGCCAC AGGAAGCCAG ACAGCAGCCC AAACCGAGAC CCAGCAACTG 
ACAAAAATGG CCACCTCGAA TCCAGTGTCA GATCCAGGGC CACATACAAG CAGCAAGAAA 
GGTACCCCTG CAGTCTCCAG GATCGAGCCT CTCAGCCCAT CCAAAAACTT CATGCCTCCA 
TCCTACATTG AACATCCACT GGATTCGAAT GAGAACAACC CCTTCTACTA CGATGATACT 
ACCCTCCGGA AACGGGGACT GCTGGTGGCT GCGGTGCTGT TCATCACGGG AATTATCATT 
CTCACTAGTG GGAAGTGTAG GCAGTTGTCT CAATTTTGCC TGAATCGCCA CAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001274142.1
CDS	255..791
Translation	MSLSSRLCLLTIVALILPSRGQTPKKPTSIFTADQTSATTRDNVPDPDQTSPGVQTTPLIWTREEATGSQTAAQTETQQLTKMATSNPVSDPGPHTSSKKGTPAVSRIEPLSPSKNFMPPSYIEHPLDSNENNPFYYDDTTLRKRGLLVAAVLFITGIIILTSGKCRQLSQFCLNRHR

Target ORF information:

RefSeq Version	NM_001287213.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus FXYD domain-containing ion transport regulator 5 (Fxyd5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001287213.1

ORF Insert Sequence:

ATGTCACTGT CCAGTCGCCT GTGTCTCCTC ACTATTGTCG CCCTGATTCT GCCCAGCAGA 
GGGCAGACAC CAAAAAAGCC CACATCCATT TTTACAGCGG ACCAGACTTC TGCGACTACT 
CGTGACAATG TCCCAGATCC AGATCAAACC AGCCCAGGAG TCCAGACCAC CCCTCTCATC 
TGGACCAGAG AAGAAGCCAC AGGAAGCCAG ACAGCAGCCC AAACCGAGAC CCAGCAACTG 
ACAAAAATGG CCACCTCGAA TCCAGTGTCA GATCCAGGGC CACATACAAG CAGCAAGAAA 
GGTACCCCTG CAGTCTCCAG GATCGAGCCT CTCAGCCCAT CCAAAAACTT CATGCCTCCA 
TCCTACATTG AACATCCACT GGATTCGAAT GAGAACAACC CCTTCTACTA CGATGATACT 
ACCCTCCGGA AACGGGGACT GCTGGTGGCT GCGGTGCTGT TCATCACGGG AATTATCATT 
CTCACTAGTG GGAAGTGTAG GCAGTTGTCT CAATTTTGCC TGAATCGCCA CAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fxyd5 ( NM_001287217.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001274146.1 Mus musculus FXYD domain-containing ion transport regulator 5 (Fxyd5), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu16846
Clone ID Related Accession (Same CDS sequence)	NM_001287217.1
Accession Version	NM_001287217.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 540bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Mus musculus(house mouse)
Product	FXYD domain-containing ion transport regulator 5 isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC149055.6. Transcript Variant: This variant (4) differs in the 5' UTR and uses an alternate in-frame splice site in the 5' coding region compared to variant 1. The encoded protein (isoform b) is longer than isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CK792201.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCACTGT CCAGTCGCCT GTGTCTCCTC ACTATTGTCG CCCTGATTCT GCCCAGCAGA 
GGGCAGACAC CAAAAAAGCC CACATCCATT TTTACAGCGG ACCAGACTTC TGCGACTACT 
CGTGACAATG TCCCAGATCC AGATCAAACC AGCCCAGGAG TCCAGACCAC CCCTCTCATC 
TGGACCAGAG AAGCAGAAGC CACAGGAAGC CAGACAGCAG CCCAAACCGA GACCCAGCAA 
CTGACAAAAA TGGCCACCTC GAATCCAGTG TCAGATCCAG GGCCACATAC AAGCAGCAAG 
AAAGGTACCC CTGCAGTCTC CAGGATCGAG CCTCTCAGCC CATCCAAAAA CTTCATGCCT 
CCATCCTACA TTGAACATCC ACTGGATTCG AATGAGAACA ACCCCTTCTA CTACGATGAT 
ACTACCCTCC GGAAACGGGG ACTGCTGGTG GCTGCGGTGC TGTTCATCAC GGGAATTATC 
ATTCTCACTA GTGGGAAGTG TAGGCAGTTG TCTCAATTTT GCCTGAATCG CCACAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001274146.1
CDS	243..782
Translation	MSLSSRLCLLTIVALILPSRGQTPKKPTSIFTADQTSATTRDNVPDPDQTSPGVQTTPLIWTREAEATGSQTAAQTETQQLTKMATSNPVSDPGPHTSSKKGTPAVSRIEPLSPSKNFMPPSYIEHPLDSNENNPFYYDDTTLRKRGLLVAAVLFITGIIILTSGKCRQLSQFCLNRHR

Target ORF information:

RefSeq Version	NM_001287217.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus FXYD domain-containing ion transport regulator 5 (Fxyd5), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001287217.1

ORF Insert Sequence:

ATGTCACTGT CCAGTCGCCT GTGTCTCCTC ACTATTGTCG CCCTGATTCT GCCCAGCAGA 
GGGCAGACAC CAAAAAAGCC CACATCCATT TTTACAGCGG ACCAGACTTC TGCGACTACT 
CGTGACAATG TCCCAGATCC AGATCAAACC AGCCCAGGAG TCCAGACCAC CCCTCTCATC 
TGGACCAGAG AAGCAGAAGC CACAGGAAGC CAGACAGCAG CCCAAACCGA GACCCAGCAA 
CTGACAAAAA TGGCCACCTC GAATCCAGTG TCAGATCCAG GGCCACATAC AAGCAGCAAG 
AAAGGTACCC CTGCAGTCTC CAGGATCGAG CCTCTCAGCC CATCCAAAAA CTTCATGCCT 
CCATCCTACA TTGAACATCC ACTGGATTCG AATGAGAACA ACCCCTTCTA CTACGATGAT 
ACTACCCTCC GGAAACGGGG ACTGCTGGTG GCTGCGGTGC TGTTCATCAC GGGAATTATC 
ATTCTCACTA GTGGGAAGTG TAGGCAGTTG TCTCAATTTT GCCTGAATCG CCACAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

FXYD5 (dysadherin) may mediate metastatic progression through regulation of the ?-Na
American journal of physiology. Cell physiology313(1)C108-C117(2017 Jul)
Lubarski-Gotliv I,Dey K,Kuznetsov Y,Kalchenco V,Asher C,Garty H

FXYD5 Protein Has a Pro-inflammatory Role in Epithelial Cells.
The Journal of biological chemistry291(21)11072-82(2016 May)
Lubarski-Gotliv I,Asher C,Dada LA,Garty H

Modulation of cell polarization by the Na+-K+-ATPase-associated protein FXYD5 (dysadherin).
American journal of physiology. Cell physiology306(11)C1080-8(2014 Jun)
Lubarski I,Asher C,Garty H

FXYD5 (dysadherin) regulates the paracellular permeability in cultured kidney collecting duct cells.
American journal of physiology. Renal physiology301(6)F1270-80(2011 Dec)
Lubarski I,Asher C,Garty H

Dysadherin can enhance tumorigenesis by conferring properties of stem-like cells to hepatocellular carcinoma cells.
Journal of hepatology54(1)122-31(2011 Jan)
Park JR,Kim RJ,Lee YK,Kim SR,Roh KJ,Oh SH,Kong G,Kang KS,Nam JS

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Fxyd5 cDNA ORF clone, Mus musculus(house mouse)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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