Dusp8 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dusp8
Entrez Gene ID	18218
Full Name	dual specificity phosphatase 8
Synonyms	5530400B01Rik,AI593498,Nttp1
General protein information	Preferred Names dual specificity phosphatase 8 Names dual specificity protein phosphatase 8 neuronal tyrosine threonine phosphatase 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7 F5\|7 87.59 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_011241989.3	XP_011240291.1	dual specificity protein phosphatase 8 isoform X1
XM_006508509.3	XP_006508572.1	dual specificity protein phosphatase 8 isoform X1
XM_006508509.4	XP_006508572.1	dual specificity protein phosphatase 8 isoform X1
NM_008748.3	NP_032774.1	dual specificity protein phosphatase 8
XM_011241989.2	XP_011240291.1	dual specificity protein phosphatase 8 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	DUSP8	NP_004411.2
Pan troglodytes (chimpanzee)	LOC746336	XP_001153496.2
Canis lupus familiaris (dog)	DUSP8	XP_854279.2
	LOC720960	XP_001116942.2
Rattus norvegicus (Norway rat)	Dusp8	NP_001101980.1
Gallus gallus (chicken)	DUSP8	XP_001232893.1
Mus musculus (house mouse)	Dusp8	NP_032774.1
Danio rerio (zebrafish)	dusp8a	NP_957174.1

Gene Ontology
Bibliography

Related articles in PubMed

DUSP8 Regulates Cardiac Ventricular Remodeling by Altering ERK1/2 Signaling.
Liu R, van Berlo JH, York AJ, Vagnozzi RJ, Maillet M, Molkentin JD
Circulation research119(2)249-60(2016 Jul)

Loss of ATF2 function leads to cranial motoneuron degeneration during embryonic mouse development.
Ackermann J, Ashton G, Lyons S, James D, Hornung JP, Jones N, Breitwieser W
PloS one6(4)e19090(2011 Apr)

Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells.
Breitwieser W, Lyons S, Flenniken AM, Ashton G, Bruder G, Willington M, Lacaud G, Kouskoff V, Jones N
Genes & development21(16)2069-82(2007 Aug)

A growing family of dual specificity phosphatases with low molecular masses.
Aoki N, Aoyama K, Nagata M, Matsuda T
Journal of biochemistry130(1)133-40(2001 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

DUSP8 controls stress-induced ERK1/2 signaling in cardiac myocytes.
Title: DUSP8 Regulates Cardiac Ventricular Remodeling by Altering ERK1/2 Signaling.

The following Dusp8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dusp8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu02697	XM_006508509.4 Latest version!	Mus musculus dual specificity phosphatase 8 (Dusp8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu02697	XM_011241989.3 Latest version!	Mus musculus dual specificity phosphatase 8 (Dusp8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu02697	NM_008748.3 Latest version!	Mus musculus dual specificity phosphatase 8 (Dusp8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OMu02697	XM_006508509.3	Mus musculus dual specificity phosphatase 8 (Dusp8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OMu02697	XM_011241989.2	Mus musculus dual specificity phosphatase 8 (Dusp8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dusp8 ( XM_011241989.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011240291.1 Mus musculus dual specificity phosphatase 8 (Dusp8), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu02697
Clone ID Related Accession (Same CDS sequence)	XM_011241989.3 , XM_006508509.3 , XM_006508509.4 , NM_008748.3 , XM_011241989.2
Accession Version	XM_011241989.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1992bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	dual specificity protein phosphatase 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011241989.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGGG ATCGGCTCCC GAGGAAGGTG ATGGACGCAA AGAAACTGGC CAGCCTGCTG 
CGTGGCGGGC CTGGGGGACC CTTGGTCATC GACAGCCGGT CCTTCGTGGA GTATAACAGC 
TGCCACGTGC TGAGCTCTGT GAATATCTGC TGTTCAAAGC TGGTGAAGCG GCGCCTTCAG 
CAGGGAAAAG TGACAATTGC TGAGCTTATC CAGCCTGCTA CACGGAGCCA GGTGGATGCC 
ACAGAACCAC AGGATGTAGT GGTGTATGAC CAGAGCACAC GAGATGCCAG CGTGCTGGCA 
GCAGACAGCT TCCTGTCCAT CCTGCTCAGC AAGCTGGACG GCTGCTTCGA CAGTGTGGCC 
ATCCTCACAG GAGGCTTCGC CACCTTCTCC TCCTGCTTCC CTGGCCTCTG TGAGGGCAAG 
CCTGCCACTC TACCGTCCAT GAGCCTCTCT CAGCCCTGCC TGCCTGTGCC CAGTGTTGGC 
CTGACCCGAA TCCTGCCTCA CCTCTACCTG GGCTCTCAGA AAGATGTCTT GAACAAGGAT 
CTGATGACCC AAAACGGAAT AAGCTATGTC CTCAATGCCA GCAACTCCTG CCCTAAACCG 
GACTTCATCT GTGAGAGCCG TTTCATGCGT ATCCCCATCA ATGACAACTA CTGTGAAAAG 
CTGCTGCCCT GGCTGGACAA GTCCATCGAG TTTATTGATA AAGCCAAGCT GTCCAGCTGC 
CAAGTCATTG TTCACTGTCT GGCTGGCATC TCTCGCTCTG CCACCATTGC CATCGCGTAC 
ATCATGAAAA CCATGGGCAT GTCTTCTGAC GACGCATACA GGTTTGTGAA GGATCGGCGC 
CCCTCCATCT CGCCCAACTT CAACTTCCTG GGCCAGTTGC TGGAGTATGA GAGGAGTCTG 
AAGCTGCTGG CTGCCCTGCA GACTGATGGA CCTCACTTGG GGACCCCTGA GCCCCTCATG 
GGCCCGGCAG CAGGCATCCC ACTGCCCCGG CTGCCACCAT CTACCTCAGA GAGCGCTGCC 
ACTGGGAGCG AGGCAGCCAC CGCAGCCAGG GAGGGCAGCC CAAGTGCTGG AGGGGATGCT 
CCGATCCCCA GCACAGCTCC AGCCACCAGC GCGCTGCAGC AGGGCCTGCG TGGCCTGCAC 
CTCTCCTCTG ACCGCCTCCA GGACACCAAC CGCCTCAAGC GTTCCTTTTC CCTGGACATC 
AAGTCGGCCT ATGCACCCAG CAGGAGGCCC GACTTTCCCG GCCCACCCGA CCCCGGTGAA 
GCCCCGAAGC TCTGCAAGCT GGACAGCCCG TCTGGGGGCA CACTGGGCCT GCCCTCGCCC 
AGCCCAGACA GCCCGGACTC CGTTCCAGAG TGCCGCCCAC GACCCCGCCG GCGACGCCCC 
CCGGCTAGTT CGCCTGCCCG CTCCCCCGCG CATGGTCTGG GCCTGAACTT TGGAGACACG 
GCCCGGCAGA CTCCACGGCA CGGCCTCTCG GCCCTGTCGG CGCCCGGGCT GCCTGGCCCT 
GGCCAGCCGG CTGGCCCCGG GGGCTGGGTG CCGCCACTGG ACTCCCCAGG CACACCGTCG 
CCCGACGGCC CCTGGTGCTT CAGCCCCGAG GGCGCGCAGG GTCCAGGCGC TGTGTTCTCC 
GCCTTTGGCC GGGTAAGTGC AGGCGCACCT GGACCCGGTA ACAGCAGCAG CAGCGGTGGT 
GGTGGTGGTG GTGGTGGCGG CGGCGGCGGC GGCGGCGGCG GCGGCGGCAG CAGCAGCAGC 
AACAGCAGCA GCAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGTAG TAGTAGTAGT 
GACCTGCGGA GGCGGGATGT GCGGACCGGC TGGCCCGAGG AGCCTGCTGC AGATGCACAG 
TTCAAGAGGC GCAGCTGCCA GATGGAGTTC GAAGAGGGCA TGGTGGAGGG GCGGGCACGT 
GGCGAGGAGC TGGCAGCCCT GGGCAAGCAA ACCAGCTTCT CTGGCAGCGT GGAGGTCATC 
GAAGTATCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011240291.1
CDS	223..2214
Translation	MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSCHVLSSVNICCSKLVKRRLQQGKVTIAELIQPATRSQVDATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCEGKPATLPSMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRIPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAALQTDGPHLGTPEPLMGPAAGIPLPRLPPSTSESAATGSEAATAAREGSPSAGGDAPIPSTAPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDFPGPPDPGEAPKLCKLDSPSGGTLGLPSPSPDSPDSVPECRPRPRRRRPPASSPARSPAHGLGLNFGDTARQTPRHGLSALSAPGLPGPGQPAGPGGWVPPLDSPGTPSPDGPWCFSPEGAQGPGAVFSAFGRVSAGAPGPGNSSSSGGGGGGGGGGGGGGGGGGSSSSNSSSSSSSSSSSSSSSSSSSDLRRRDVRTGWPEEPAADAQFKRRSCQMEFEEGMVEGRARGEELAALGKQTSFSGSVEVIEVS

Target ORF information:

RefSeq Version	XM_011241989.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual specificity phosphatase 8 (Dusp8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011241989.3

ORF Insert Sequence:

ATGGCTGGGG ATCGGCTCCC GAGGAAGGTG ATGGACGCAA AGAAACTGGC CAGCCTGCTG 
CGTGGCGGGC CTGGGGGACC CTTGGTCATC GACAGCCGGT CCTTCGTGGA GTATAACAGC 
TGCCACGTGC TGAGCTCTGT GAATATCTGC TGTTCAAAGC TGGTGAAGCG GCGCCTTCAG 
CAGGGAAAAG TGACAATTGC TGAGCTTATC CAGCCTGCTA CACGGAGCCA GGTGGATGCC 
ACAGAACCAC AGGATGTAGT GGTGTATGAC CAGAGCACAC GAGATGCCAG CGTGCTGGCA 
GCAGACAGCT TCCTGTCCAT CCTGCTCAGC AAGCTGGACG GCTGCTTCGA CAGTGTGGCC 
ATCCTCACAG GAGGCTTCGC CACCTTCTCC TCCTGCTTCC CTGGCCTCTG TGAGGGCAAG 
CCTGCCACTC TACCGTCCAT GAGCCTCTCT CAGCCCTGCC TGCCTGTGCC CAGTGTTGGC 
CTGACCCGAA TCCTGCCTCA CCTCTACCTG GGCTCTCAGA AAGATGTCTT GAACAAGGAT 
CTGATGACCC AAAACGGAAT AAGCTATGTC CTCAATGCCA GCAACTCCTG CCCTAAACCG 
GACTTCATCT GTGAGAGCCG TTTCATGCGT ATCCCCATCA ATGACAACTA CTGTGAAAAG 
CTGCTGCCCT GGCTGGACAA GTCCATCGAG TTTATTGATA AAGCCAAGCT GTCCAGCTGC 
CAAGTCATTG TTCACTGTCT GGCTGGCATC TCTCGCTCTG CCACCATTGC CATCGCGTAC 
ATCATGAAAA CCATGGGCAT GTCTTCTGAC GACGCATACA GGTTTGTGAA GGATCGGCGC 
CCCTCCATCT CGCCCAACTT CAACTTCCTG GGCCAGTTGC TGGAGTATGA GAGGAGTCTG 
AAGCTGCTGG CTGCCCTGCA GACTGATGGA CCTCACTTGG GGACCCCTGA GCCCCTCATG 
GGCCCGGCAG CAGGCATCCC ACTGCCCCGG CTGCCACCAT CTACCTCAGA GAGCGCTGCC 
ACTGGGAGCG AGGCAGCCAC CGCAGCCAGG GAGGGCAGCC CAAGTGCTGG AGGGGATGCT 
CCGATCCCCA GCACAGCTCC AGCCACCAGC GCGCTGCAGC AGGGCCTGCG TGGCCTGCAC 
CTCTCCTCTG ACCGCCTCCA GGACACCAAC CGCCTCAAGC GTTCCTTTTC CCTGGACATC 
AAGTCGGCCT ATGCACCCAG CAGGAGGCCC GACTTTCCCG GCCCACCCGA CCCCGGTGAA 
GCCCCGAAGC TCTGCAAGCT GGACAGCCCG TCTGGGGGCA CACTGGGCCT GCCCTCGCCC 
AGCCCAGACA GCCCGGACTC CGTTCCAGAG TGCCGCCCAC GACCCCGCCG GCGACGCCCC 
CCGGCTAGTT CGCCTGCCCG CTCCCCCGCG CATGGTCTGG GCCTGAACTT TGGAGACACG 
GCCCGGCAGA CTCCACGGCA CGGCCTCTCG GCCCTGTCGG CGCCCGGGCT GCCTGGCCCT 
GGCCAGCCGG CTGGCCCCGG GGGCTGGGTG CCGCCACTGG ACTCCCCAGG CACACCGTCG 
CCCGACGGCC CCTGGTGCTT CAGCCCCGAG GGCGCGCAGG GTCCAGGCGC TGTGTTCTCC 
GCCTTTGGCC GGGTAAGTGC AGGCGCACCT GGACCCGGTA ACAGCAGCAG CAGCGGTGGT 
GGTGGTGGTG GTGGTGGCGG CGGCGGCGGC GGCGGCGGCG GCGGCGGCAG CAGCAGCAGC 
AACAGCAGCA GCAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGTAG TAGTAGTAGT 
GACCTGCGGA GGCGGGATGT GCGGACCGGC TGGCCCGAGG AGCCTGCTGC AGATGCACAG 
TTCAAGAGGC GCAGCTGCCA GATGGAGTTC GAAGAGGGCA TGGTGGAGGG GCGGGCACGT 
GGCGAGGAGC TGGCAGCCCT GGGCAAGCAA ACCAGCTTCT CTGGCAGCGT GGAGGTCATC 
GAAGTATCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dusp8 ( XM_006508509.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006508572.1 Mus musculus dual specificity phosphatase 8 (Dusp8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu02697
Clone ID Related Accession (Same CDS sequence)	XM_011241989.3 , XM_006508509.3 , XM_006508509.4 , NM_008748.3 , XM_011241989.2
Accession Version	XM_006508509.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1992bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	dual specificity protein phosphatase 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006508509.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGGG ATCGGCTCCC GAGGAAGGTG ATGGACGCAA AGAAACTGGC CAGCCTGCTG 
CGTGGCGGGC CTGGGGGACC CTTGGTCATC GACAGCCGGT CCTTCGTGGA GTATAACAGC 
TGCCACGTGC TGAGCTCTGT GAATATCTGC TGTTCAAAGC TGGTGAAGCG GCGCCTTCAG 
CAGGGAAAAG TGACAATTGC TGAGCTTATC CAGCCTGCTA CACGGAGCCA GGTGGATGCC 
ACAGAACCAC AGGATGTAGT GGTGTATGAC CAGAGCACAC GAGATGCCAG CGTGCTGGCA 
GCAGACAGCT TCCTGTCCAT CCTGCTCAGC AAGCTGGACG GCTGCTTCGA CAGTGTGGCC 
ATCCTCACAG GAGGCTTCGC CACCTTCTCC TCCTGCTTCC CTGGCCTCTG TGAGGGCAAG 
CCTGCCACTC TACCGTCCAT GAGCCTCTCT CAGCCCTGCC TGCCTGTGCC CAGTGTTGGC 
CTGACCCGAA TCCTGCCTCA CCTCTACCTG GGCTCTCAGA AAGATGTCTT GAACAAGGAT 
CTGATGACCC AAAACGGAAT AAGCTATGTC CTCAATGCCA GCAACTCCTG CCCTAAACCG 
GACTTCATCT GTGAGAGCCG TTTCATGCGT ATCCCCATCA ATGACAACTA CTGTGAAAAG 
CTGCTGCCCT GGCTGGACAA GTCCATCGAG TTTATTGATA AAGCCAAGCT GTCCAGCTGC 
CAAGTCATTG TTCACTGTCT GGCTGGCATC TCTCGCTCTG CCACCATTGC CATCGCGTAC 
ATCATGAAAA CCATGGGCAT GTCTTCTGAC GACGCATACA GGTTTGTGAA GGATCGGCGC 
CCCTCCATCT CGCCCAACTT CAACTTCCTG GGCCAGTTGC TGGAGTATGA GAGGAGTCTG 
AAGCTGCTGG CTGCCCTGCA GACTGATGGA CCTCACTTGG GGACCCCTGA GCCCCTCATG 
GGCCCGGCAG CAGGCATCCC ACTGCCCCGG CTGCCACCAT CTACCTCAGA GAGCGCTGCC 
ACTGGGAGCG AGGCAGCCAC CGCAGCCAGG GAGGGCAGCC CAAGTGCTGG AGGGGATGCT 
CCGATCCCCA GCACAGCTCC AGCCACCAGC GCGCTGCAGC AGGGCCTGCG TGGCCTGCAC 
CTCTCCTCTG ACCGCCTCCA GGACACCAAC CGCCTCAAGC GTTCCTTTTC CCTGGACATC 
AAGTCGGCCT ATGCACCCAG CAGGAGGCCC GACTTTCCCG GCCCACCCGA CCCCGGTGAA 
GCCCCGAAGC TCTGCAAGCT GGACAGCCCG TCTGGGGGCA CACTGGGCCT GCCCTCGCCC 
AGCCCAGACA GCCCGGACTC CGTTCCAGAG TGCCGCCCAC GACCCCGCCG GCGACGCCCC 
CCGGCTAGTT CGCCTGCCCG CTCCCCCGCG CATGGTCTGG GCCTGAACTT TGGAGACACG 
GCCCGGCAGA CTCCACGGCA CGGCCTCTCG GCCCTGTCGG CGCCCGGGCT GCCTGGCCCT 
GGCCAGCCGG CTGGCCCCGG GGGCTGGGTG CCGCCACTGG ACTCCCCAGG CACACCGTCG 
CCCGACGGCC CCTGGTGCTT CAGCCCCGAG GGCGCGCAGG GTCCAGGCGC TGTGTTCTCC 
GCCTTTGGCC GGGTAAGTGC AGGCGCACCT GGACCCGGTA ACAGCAGCAG CAGCGGTGGT 
GGTGGTGGTG GTGGTGGCGG CGGCGGCGGC GGCGGCGGCG GCGGCGGCAG CAGCAGCAGC 
AACAGCAGCA GCAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGTAG TAGTAGTAGT 
GACCTGCGGA GGCGGGATGT GCGGACCGGC TGGCCCGAGG AGCCTGCTGC AGATGCACAG 
TTCAAGAGGC GCAGCTGCCA GATGGAGTTC GAAGAGGGCA TGGTGGAGGG GCGGGCACGT 
GGCGAGGAGC TGGCAGCCCT GGGCAAGCAA ACCAGCTTCT CTGGCAGCGT GGAGGTCATC 
GAAGTATCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006508572.1
CDS	843..2834
Translation	MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSCHVLSSVNICCSKLVKRRLQQGKVTIAELIQPATRSQVDATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCEGKPATLPSMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRIPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAALQTDGPHLGTPEPLMGPAAGIPLPRLPPSTSESAATGSEAATAAREGSPSAGGDAPIPSTAPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDFPGPPDPGEAPKLCKLDSPSGGTLGLPSPSPDSPDSVPECRPRPRRRRPPASSPARSPAHGLGLNFGDTARQTPRHGLSALSAPGLPGPGQPAGPGGWVPPLDSPGTPSPDGPWCFSPEGAQGPGAVFSAFGRVSAGAPGPGNSSSSGGGGGGGGGGGGGGGGGGSSSSNSSSSSSSSSSSSSSSSSSSDLRRRDVRTGWPEEPAADAQFKRRSCQMEFEEGMVEGRARGEELAALGKQTSFSGSVEVIEVS

Target ORF information:

RefSeq Version	XM_006508509.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual specificity phosphatase 8 (Dusp8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006508509.4

ORF Insert Sequence:

ATGGCTGGGG ATCGGCTCCC GAGGAAGGTG ATGGACGCAA AGAAACTGGC CAGCCTGCTG 
CGTGGCGGGC CTGGGGGACC CTTGGTCATC GACAGCCGGT CCTTCGTGGA GTATAACAGC 
TGCCACGTGC TGAGCTCTGT GAATATCTGC TGTTCAAAGC TGGTGAAGCG GCGCCTTCAG 
CAGGGAAAAG TGACAATTGC TGAGCTTATC CAGCCTGCTA CACGGAGCCA GGTGGATGCC 
ACAGAACCAC AGGATGTAGT GGTGTATGAC CAGAGCACAC GAGATGCCAG CGTGCTGGCA 
GCAGACAGCT TCCTGTCCAT CCTGCTCAGC AAGCTGGACG GCTGCTTCGA CAGTGTGGCC 
ATCCTCACAG GAGGCTTCGC CACCTTCTCC TCCTGCTTCC CTGGCCTCTG TGAGGGCAAG 
CCTGCCACTC TACCGTCCAT GAGCCTCTCT CAGCCCTGCC TGCCTGTGCC CAGTGTTGGC 
CTGACCCGAA TCCTGCCTCA CCTCTACCTG GGCTCTCAGA AAGATGTCTT GAACAAGGAT 
CTGATGACCC AAAACGGAAT AAGCTATGTC CTCAATGCCA GCAACTCCTG CCCTAAACCG 
GACTTCATCT GTGAGAGCCG TTTCATGCGT ATCCCCATCA ATGACAACTA CTGTGAAAAG 
CTGCTGCCCT GGCTGGACAA GTCCATCGAG TTTATTGATA AAGCCAAGCT GTCCAGCTGC 
CAAGTCATTG TTCACTGTCT GGCTGGCATC TCTCGCTCTG CCACCATTGC CATCGCGTAC 
ATCATGAAAA CCATGGGCAT GTCTTCTGAC GACGCATACA GGTTTGTGAA GGATCGGCGC 
CCCTCCATCT CGCCCAACTT CAACTTCCTG GGCCAGTTGC TGGAGTATGA GAGGAGTCTG 
AAGCTGCTGG CTGCCCTGCA GACTGATGGA CCTCACTTGG GGACCCCTGA GCCCCTCATG 
GGCCCGGCAG CAGGCATCCC ACTGCCCCGG CTGCCACCAT CTACCTCAGA GAGCGCTGCC 
ACTGGGAGCG AGGCAGCCAC CGCAGCCAGG GAGGGCAGCC CAAGTGCTGG AGGGGATGCT 
CCGATCCCCA GCACAGCTCC AGCCACCAGC GCGCTGCAGC AGGGCCTGCG TGGCCTGCAC 
CTCTCCTCTG ACCGCCTCCA GGACACCAAC CGCCTCAAGC GTTCCTTTTC CCTGGACATC 
AAGTCGGCCT ATGCACCCAG CAGGAGGCCC GACTTTCCCG GCCCACCCGA CCCCGGTGAA 
GCCCCGAAGC TCTGCAAGCT GGACAGCCCG TCTGGGGGCA CACTGGGCCT GCCCTCGCCC 
AGCCCAGACA GCCCGGACTC CGTTCCAGAG TGCCGCCCAC GACCCCGCCG GCGACGCCCC 
CCGGCTAGTT CGCCTGCCCG CTCCCCCGCG CATGGTCTGG GCCTGAACTT TGGAGACACG 
GCCCGGCAGA CTCCACGGCA CGGCCTCTCG GCCCTGTCGG CGCCCGGGCT GCCTGGCCCT 
GGCCAGCCGG CTGGCCCCGG GGGCTGGGTG CCGCCACTGG ACTCCCCAGG CACACCGTCG 
CCCGACGGCC CCTGGTGCTT CAGCCCCGAG GGCGCGCAGG GTCCAGGCGC TGTGTTCTCC 
GCCTTTGGCC GGGTAAGTGC AGGCGCACCT GGACCCGGTA ACAGCAGCAG CAGCGGTGGT 
GGTGGTGGTG GTGGTGGCGG CGGCGGCGGC GGCGGCGGCG GCGGCGGCAG CAGCAGCAGC 
AACAGCAGCA GCAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGTAG TAGTAGTAGT 
GACCTGCGGA GGCGGGATGT GCGGACCGGC TGGCCCGAGG AGCCTGCTGC AGATGCACAG 
TTCAAGAGGC GCAGCTGCCA GATGGAGTTC GAAGAGGGCA TGGTGGAGGG GCGGGCACGT 
GGCGAGGAGC TGGCAGCCCT GGGCAAGCAA ACCAGCTTCT CTGGCAGCGT GGAGGTCATC 
GAAGTATCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dusp8 ( NM_008748.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032774.1 Mus musculus dual specificity phosphatase 8 (Dusp8), mRNA.

Price & Availability↑

CloneID	OMu02697
Clone ID Related Accession (Same CDS sequence)	XM_011241989.3 , XM_006508509.3 , XM_006508509.4 , NM_008748.3 , XM_011241989.2
Accession Version	NM_008748.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1992bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	dual specificity protein phosphatase 8
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL603836.13, BC052705.1 and BQ043453.1. On Mar 26, 2011 this sequence version replaced NM_008748.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC052705.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164138 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGGGG ATCGGCTCCC GAGGAAGGTG ATGGACGCAA AGAAACTGGC CAGCCTGCTG 
CGTGGCGGGC CTGGGGGACC CTTGGTCATC GACAGCCGGT CCTTCGTGGA GTATAACAGC 
TGCCACGTGC TGAGCTCTGT GAATATCTGC TGTTCAAAGC TGGTGAAGCG GCGCCTTCAG 
CAGGGAAAAG TGACAATTGC TGAGCTTATC CAGCCTGCTA CACGGAGCCA GGTGGATGCC 
ACAGAACCAC AGGATGTAGT GGTGTATGAC CAGAGCACAC GAGATGCCAG CGTGCTGGCA 
GCAGACAGCT TCCTGTCCAT CCTGCTCAGC AAGCTGGACG GCTGCTTCGA CAGTGTGGCC 
ATCCTCACAG GAGGCTTCGC CACCTTCTCC TCCTGCTTCC CTGGCCTCTG TGAGGGCAAG 
CCTGCCACTC TACCGTCCAT GAGCCTCTCT CAGCCCTGCC TGCCTGTGCC CAGTGTTGGC 
CTGACCCGAA TCCTGCCTCA CCTCTACCTG GGCTCTCAGA AAGATGTCTT GAACAAGGAT 
CTGATGACCC AAAACGGAAT AAGCTATGTC CTCAATGCCA GCAACTCCTG CCCTAAACCG 
GACTTCATCT GTGAGAGCCG TTTCATGCGT ATCCCCATCA ATGACAACTA CTGTGAAAAG 
CTGCTGCCCT GGCTGGACAA GTCCATCGAG TTTATTGATA AAGCCAAGCT GTCCAGCTGC 
CAAGTCATTG TTCACTGTCT GGCTGGCATC TCTCGCTCTG CCACCATTGC CATCGCGTAC 
ATCATGAAAA CCATGGGCAT GTCTTCTGAC GACGCATACA GGTTTGTGAA GGATCGGCGC 
CCCTCCATCT CGCCCAACTT CAACTTCCTG GGCCAGTTGC TGGAGTATGA GAGGAGTCTG 
AAGCTGCTGG CTGCCCTGCA GACTGATGGA CCTCACTTGG GGACCCCTGA GCCCCTCATG 
GGCCCGGCAG CAGGCATCCC ACTGCCCCGG CTGCCACCAT CTACCTCAGA GAGCGCTGCC 
ACTGGGAGCG AGGCAGCCAC CGCAGCCAGG GAGGGCAGCC CAAGTGCTGG AGGGGATGCT 
CCGATCCCCA GCACAGCTCC AGCCACCAGC GCGCTGCAGC AGGGCCTGCG TGGCCTGCAC 
CTCTCCTCTG ACCGCCTCCA GGACACCAAC CGCCTCAAGC GTTCCTTTTC CCTGGACATC 
AAGTCGGCCT ATGCACCCAG CAGGAGGCCC GACTTTCCCG GCCCACCCGA CCCCGGTGAA 
GCCCCGAAGC TCTGCAAGCT GGACAGCCCG TCTGGGGGCA CACTGGGCCT GCCCTCGCCC 
AGCCCAGACA GCCCGGACTC CGTTCCAGAG TGCCGCCCAC GACCCCGCCG GCGACGCCCC 
CCGGCTAGTT CGCCTGCCCG CTCCCCCGCG CATGGTCTGG GCCTGAACTT TGGAGACACG 
GCCCGGCAGA CTCCACGGCA CGGCCTCTCG GCCCTGTCGG CGCCCGGGCT GCCTGGCCCT 
GGCCAGCCGG CTGGCCCCGG GGGCTGGGTG CCGCCACTGG ACTCCCCAGG CACACCGTCG 
CCCGACGGCC CCTGGTGCTT CAGCCCCGAG GGCGCGCAGG GTCCAGGCGC TGTGTTCTCC 
GCCTTTGGCC GGGTAAGTGC AGGCGCACCT GGACCCGGTA ACAGCAGCAG CAGCGGTGGT 
GGTGGTGGTG GTGGTGGCGG CGGCGGCGGC GGCGGCGGCG GCGGCGGCAG CAGCAGCAGC 
AACAGCAGCA GCAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGTAG TAGTAGTAGT 
GACCTGCGGA GGCGGGATGT GCGGACCGGC TGGCCCGAGG AGCCTGCTGC AGATGCACAG 
TTCAAGAGGC GCAGCTGCCA GATGGAGTTC GAAGAGGGCA TGGTGGAGGG GCGGGCACGT 
GGCGAGGAGC TGGCAGCCCT GGGCAAGCAA ACCAGCTTCT CTGGCAGCGT GGAGGTCATC 
GAAGTATCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032774.1
CDS	455..2446
Translation	MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSCHVLSSVNICCSKLVKRRLQQGKVTIAELIQPATRSQVDATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCEGKPATLPSMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRIPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAALQTDGPHLGTPEPLMGPAAGIPLPRLPPSTSESAATGSEAATAAREGSPSAGGDAPIPSTAPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDFPGPPDPGEAPKLCKLDSPSGGTLGLPSPSPDSPDSVPECRPRPRRRRPPASSPARSPAHGLGLNFGDTARQTPRHGLSALSAPGLPGPGQPAGPGGWVPPLDSPGTPSPDGPWCFSPEGAQGPGAVFSAFGRVSAGAPGPGNSSSSGGGGGGGGGGGGGGGGGGSSSSNSSSSSSSSSSSSSSSSSSSDLRRRDVRTGWPEEPAADAQFKRRSCQMEFEEGMVEGRARGEELAALGKQTSFSGSVEVIEVS

Target ORF information:

RefSeq Version	NM_008748.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual specificity phosphatase 8 (Dusp8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008748.3

ORF Insert Sequence:

ATGGCTGGGG ATCGGCTCCC GAGGAAGGTG ATGGACGCAA AGAAACTGGC CAGCCTGCTG 
CGTGGCGGGC CTGGGGGACC CTTGGTCATC GACAGCCGGT CCTTCGTGGA GTATAACAGC 
TGCCACGTGC TGAGCTCTGT GAATATCTGC TGTTCAAAGC TGGTGAAGCG GCGCCTTCAG 
CAGGGAAAAG TGACAATTGC TGAGCTTATC CAGCCTGCTA CACGGAGCCA GGTGGATGCC 
ACAGAACCAC AGGATGTAGT GGTGTATGAC CAGAGCACAC GAGATGCCAG CGTGCTGGCA 
GCAGACAGCT TCCTGTCCAT CCTGCTCAGC AAGCTGGACG GCTGCTTCGA CAGTGTGGCC 
ATCCTCACAG GAGGCTTCGC CACCTTCTCC TCCTGCTTCC CTGGCCTCTG TGAGGGCAAG 
CCTGCCACTC TACCGTCCAT GAGCCTCTCT CAGCCCTGCC TGCCTGTGCC CAGTGTTGGC 
CTGACCCGAA TCCTGCCTCA CCTCTACCTG GGCTCTCAGA AAGATGTCTT GAACAAGGAT 
CTGATGACCC AAAACGGAAT AAGCTATGTC CTCAATGCCA GCAACTCCTG CCCTAAACCG 
GACTTCATCT GTGAGAGCCG TTTCATGCGT ATCCCCATCA ATGACAACTA CTGTGAAAAG 
CTGCTGCCCT GGCTGGACAA GTCCATCGAG TTTATTGATA AAGCCAAGCT GTCCAGCTGC 
CAAGTCATTG TTCACTGTCT GGCTGGCATC TCTCGCTCTG CCACCATTGC CATCGCGTAC 
ATCATGAAAA CCATGGGCAT GTCTTCTGAC GACGCATACA GGTTTGTGAA GGATCGGCGC 
CCCTCCATCT CGCCCAACTT CAACTTCCTG GGCCAGTTGC TGGAGTATGA GAGGAGTCTG 
AAGCTGCTGG CTGCCCTGCA GACTGATGGA CCTCACTTGG GGACCCCTGA GCCCCTCATG 
GGCCCGGCAG CAGGCATCCC ACTGCCCCGG CTGCCACCAT CTACCTCAGA GAGCGCTGCC 
ACTGGGAGCG AGGCAGCCAC CGCAGCCAGG GAGGGCAGCC CAAGTGCTGG AGGGGATGCT 
CCGATCCCCA GCACAGCTCC AGCCACCAGC GCGCTGCAGC AGGGCCTGCG TGGCCTGCAC 
CTCTCCTCTG ACCGCCTCCA GGACACCAAC CGCCTCAAGC GTTCCTTTTC CCTGGACATC 
AAGTCGGCCT ATGCACCCAG CAGGAGGCCC GACTTTCCCG GCCCACCCGA CCCCGGTGAA 
GCCCCGAAGC TCTGCAAGCT GGACAGCCCG TCTGGGGGCA CACTGGGCCT GCCCTCGCCC 
AGCCCAGACA GCCCGGACTC CGTTCCAGAG TGCCGCCCAC GACCCCGCCG GCGACGCCCC 
CCGGCTAGTT CGCCTGCCCG CTCCCCCGCG CATGGTCTGG GCCTGAACTT TGGAGACACG 
GCCCGGCAGA CTCCACGGCA CGGCCTCTCG GCCCTGTCGG CGCCCGGGCT GCCTGGCCCT 
GGCCAGCCGG CTGGCCCCGG GGGCTGGGTG CCGCCACTGG ACTCCCCAGG CACACCGTCG 
CCCGACGGCC CCTGGTGCTT CAGCCCCGAG GGCGCGCAGG GTCCAGGCGC TGTGTTCTCC 
GCCTTTGGCC GGGTAAGTGC AGGCGCACCT GGACCCGGTA ACAGCAGCAG CAGCGGTGGT 
GGTGGTGGTG GTGGTGGCGG CGGCGGCGGC GGCGGCGGCG GCGGCGGCAG CAGCAGCAGC 
AACAGCAGCA GCAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGTAG TAGTAGTAGT 
GACCTGCGGA GGCGGGATGT GCGGACCGGC TGGCCCGAGG AGCCTGCTGC AGATGCACAG 
TTCAAGAGGC GCAGCTGCCA GATGGAGTTC GAAGAGGGCA TGGTGGAGGG GCGGGCACGT 
GGCGAGGAGC TGGCAGCCCT GGGCAAGCAA ACCAGCTTCT CTGGCAGCGT GGAGGTCATC 
GAAGTATCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dusp8 ( XM_006508509.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006508572.1 Mus musculus dual specificity phosphatase 8 (Dusp8), transcript variant X2, mRNA.

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CloneID	OMu02697
Clone ID Related Accession (Same CDS sequence)	XM_011241989.3 , XM_006508509.3 , XM_006508509.4 , NM_008748.3 , XM_011241989.2
Accession Version	XM_006508509.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1992bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	dual specificity protein phosphatase 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006508509.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGGG ATCGGCTCCC GAGGAAGGTG ATGGACGCAA AGAAACTGGC CAGCCTGCTG 
CGTGGCGGGC CTGGGGGACC CTTGGTCATC GACAGCCGGT CCTTCGTGGA GTATAACAGC 
TGCCACGTGC TGAGCTCTGT GAATATCTGC TGTTCAAAGC TGGTGAAGCG GCGCCTTCAG 
CAGGGAAAAG TGACAATTGC TGAGCTTATC CAGCCTGCTA CACGGAGCCA GGTGGATGCC 
ACAGAACCAC AGGATGTAGT GGTGTATGAC CAGAGCACAC GAGATGCCAG CGTGCTGGCA 
GCAGACAGCT TCCTGTCCAT CCTGCTCAGC AAGCTGGACG GCTGCTTCGA CAGTGTGGCC 
ATCCTCACAG GAGGCTTCGC CACCTTCTCC TCCTGCTTCC CTGGCCTCTG TGAGGGCAAG 
CCTGCCACTC TACCGTCCAT GAGCCTCTCT CAGCCCTGCC TGCCTGTGCC CAGTGTTGGC 
CTGACCCGAA TCCTGCCTCA CCTCTACCTG GGCTCTCAGA AAGATGTCTT GAACAAGGAT 
CTGATGACCC AAAACGGAAT AAGCTATGTC CTCAATGCCA GCAACTCCTG CCCTAAACCG 
GACTTCATCT GTGAGAGCCG TTTCATGCGT ATCCCCATCA ATGACAACTA CTGTGAAAAG 
CTGCTGCCCT GGCTGGACAA GTCCATCGAG TTTATTGATA AAGCCAAGCT GTCCAGCTGC 
CAAGTCATTG TTCACTGTCT GGCTGGCATC TCTCGCTCTG CCACCATTGC CATCGCGTAC 
ATCATGAAAA CCATGGGCAT GTCTTCTGAC GACGCATACA GGTTTGTGAA GGATCGGCGC 
CCCTCCATCT CGCCCAACTT CAACTTCCTG GGCCAGTTGC TGGAGTATGA GAGGAGTCTG 
AAGCTGCTGG CTGCCCTGCA GACTGATGGA CCTCACTTGG GGACCCCTGA GCCCCTCATG 
GGCCCGGCAG CAGGCATCCC ACTGCCCCGG CTGCCACCAT CTACCTCAGA GAGCGCTGCC 
ACTGGGAGCG AGGCAGCCAC CGCAGCCAGG GAGGGCAGCC CAAGTGCTGG AGGGGATGCT 
CCGATCCCCA GCACAGCTCC AGCCACCAGC GCGCTGCAGC AGGGCCTGCG TGGCCTGCAC 
CTCTCCTCTG ACCGCCTCCA GGACACCAAC CGCCTCAAGC GTTCCTTTTC CCTGGACATC 
AAGTCGGCCT ATGCACCCAG CAGGAGGCCC GACTTTCCCG GCCCACCCGA CCCCGGTGAA 
GCCCCGAAGC TCTGCAAGCT GGACAGCCCG TCTGGGGGCA CACTGGGCCT GCCCTCGCCC 
AGCCCAGACA GCCCGGACTC CGTTCCAGAG TGCCGCCCAC GACCCCGCCG GCGACGCCCC 
CCGGCTAGTT CGCCTGCCCG CTCCCCCGCG CATGGTCTGG GCCTGAACTT TGGAGACACG 
GCCCGGCAGA CTCCACGGCA CGGCCTCTCG GCCCTGTCGG CGCCCGGGCT GCCTGGCCCT 
GGCCAGCCGG CTGGCCCCGG GGGCTGGGTG CCGCCACTGG ACTCCCCAGG CACACCGTCG 
CCCGACGGCC CCTGGTGCTT CAGCCCCGAG GGCGCGCAGG GTCCAGGCGC TGTGTTCTCC 
GCCTTTGGCC GGGTAAGTGC AGGCGCACCT GGACCCGGTA ACAGCAGCAG CAGCGGTGGT 
GGTGGTGGTG GTGGTGGCGG CGGCGGCGGC GGCGGCGGCG GCGGCGGCAG CAGCAGCAGC 
AACAGCAGCA GCAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGTAG TAGTAGTAGT 
GACCTGCGGA GGCGGGATGT GCGGACCGGC TGGCCCGAGG AGCCTGCTGC AGATGCACAG 
TTCAAGAGGC GCAGCTGCCA GATGGAGTTC GAAGAGGGCA TGGTGGAGGG GCGGGCACGT 
GGCGAGGAGC TGGCAGCCCT GGGCAAGCAA ACCAGCTTCT CTGGCAGCGT GGAGGTCATC 
GAAGTATCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006508572.1
CDS	409..2400
Translation	MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSCHVLSSVNICCSKLVKRRLQQGKVTIAELIQPATRSQVDATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCEGKPATLPSMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRIPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAALQTDGPHLGTPEPLMGPAAGIPLPRLPPSTSESAATGSEAATAAREGSPSAGGDAPIPSTAPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDFPGPPDPGEAPKLCKLDSPSGGTLGLPSPSPDSPDSVPECRPRPRRRRPPASSPARSPAHGLGLNFGDTARQTPRHGLSALSAPGLPGPGQPAGPGGWVPPLDSPGTPSPDGPWCFSPEGAQGPGAVFSAFGRVSAGAPGPGNSSSSGGGGGGGGGGGGGGGGGGSSSSNSSSSSSSSSSSSSSSSSSSDLRRRDVRTGWPEEPAADAQFKRRSCQMEFEEGMVEGRARGEELAALGKQTSFSGSVEVIEVS

Target ORF information:

RefSeq Version	XM_006508509.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual specificity phosphatase 8 (Dusp8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006508509.3

ORF Insert Sequence:

ATGGCTGGGG ATCGGCTCCC GAGGAAGGTG ATGGACGCAA AGAAACTGGC CAGCCTGCTG 
CGTGGCGGGC CTGGGGGACC CTTGGTCATC GACAGCCGGT CCTTCGTGGA GTATAACAGC 
TGCCACGTGC TGAGCTCTGT GAATATCTGC TGTTCAAAGC TGGTGAAGCG GCGCCTTCAG 
CAGGGAAAAG TGACAATTGC TGAGCTTATC CAGCCTGCTA CACGGAGCCA GGTGGATGCC 
ACAGAACCAC AGGATGTAGT GGTGTATGAC CAGAGCACAC GAGATGCCAG CGTGCTGGCA 
GCAGACAGCT TCCTGTCCAT CCTGCTCAGC AAGCTGGACG GCTGCTTCGA CAGTGTGGCC 
ATCCTCACAG GAGGCTTCGC CACCTTCTCC TCCTGCTTCC CTGGCCTCTG TGAGGGCAAG 
CCTGCCACTC TACCGTCCAT GAGCCTCTCT CAGCCCTGCC TGCCTGTGCC CAGTGTTGGC 
CTGACCCGAA TCCTGCCTCA CCTCTACCTG GGCTCTCAGA AAGATGTCTT GAACAAGGAT 
CTGATGACCC AAAACGGAAT AAGCTATGTC CTCAATGCCA GCAACTCCTG CCCTAAACCG 
GACTTCATCT GTGAGAGCCG TTTCATGCGT ATCCCCATCA ATGACAACTA CTGTGAAAAG 
CTGCTGCCCT GGCTGGACAA GTCCATCGAG TTTATTGATA AAGCCAAGCT GTCCAGCTGC 
CAAGTCATTG TTCACTGTCT GGCTGGCATC TCTCGCTCTG CCACCATTGC CATCGCGTAC 
ATCATGAAAA CCATGGGCAT GTCTTCTGAC GACGCATACA GGTTTGTGAA GGATCGGCGC 
CCCTCCATCT CGCCCAACTT CAACTTCCTG GGCCAGTTGC TGGAGTATGA GAGGAGTCTG 
AAGCTGCTGG CTGCCCTGCA GACTGATGGA CCTCACTTGG GGACCCCTGA GCCCCTCATG 
GGCCCGGCAG CAGGCATCCC ACTGCCCCGG CTGCCACCAT CTACCTCAGA GAGCGCTGCC 
ACTGGGAGCG AGGCAGCCAC CGCAGCCAGG GAGGGCAGCC CAAGTGCTGG AGGGGATGCT 
CCGATCCCCA GCACAGCTCC AGCCACCAGC GCGCTGCAGC AGGGCCTGCG TGGCCTGCAC 
CTCTCCTCTG ACCGCCTCCA GGACACCAAC CGCCTCAAGC GTTCCTTTTC CCTGGACATC 
AAGTCGGCCT ATGCACCCAG CAGGAGGCCC GACTTTCCCG GCCCACCCGA CCCCGGTGAA 
GCCCCGAAGC TCTGCAAGCT GGACAGCCCG TCTGGGGGCA CACTGGGCCT GCCCTCGCCC 
AGCCCAGACA GCCCGGACTC CGTTCCAGAG TGCCGCCCAC GACCCCGCCG GCGACGCCCC 
CCGGCTAGTT CGCCTGCCCG CTCCCCCGCG CATGGTCTGG GCCTGAACTT TGGAGACACG 
GCCCGGCAGA CTCCACGGCA CGGCCTCTCG GCCCTGTCGG CGCCCGGGCT GCCTGGCCCT 
GGCCAGCCGG CTGGCCCCGG GGGCTGGGTG CCGCCACTGG ACTCCCCAGG CACACCGTCG 
CCCGACGGCC CCTGGTGCTT CAGCCCCGAG GGCGCGCAGG GTCCAGGCGC TGTGTTCTCC 
GCCTTTGGCC GGGTAAGTGC AGGCGCACCT GGACCCGGTA ACAGCAGCAG CAGCGGTGGT 
GGTGGTGGTG GTGGTGGCGG CGGCGGCGGC GGCGGCGGCG GCGGCGGCAG CAGCAGCAGC 
AACAGCAGCA GCAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGTAG TAGTAGTAGT 
GACCTGCGGA GGCGGGATGT GCGGACCGGC TGGCCCGAGG AGCCTGCTGC AGATGCACAG 
TTCAAGAGGC GCAGCTGCCA GATGGAGTTC GAAGAGGGCA TGGTGGAGGG GCGGGCACGT 
GGCGAGGAGC TGGCAGCCCT GGGCAAGCAA ACCAGCTTCT CTGGCAGCGT GGAGGTCATC 
GAAGTATCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dusp8 ( XM_011241989.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011240291.1 Mus musculus dual specificity phosphatase 8 (Dusp8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu02697
Clone ID Related Accession (Same CDS sequence)	XM_011241989.3 , XM_006508509.3 , XM_006508509.4 , NM_008748.3 , XM_011241989.2
Accession Version	XM_011241989.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1992bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	dual specificity protein phosphatase 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011241989.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGGG ATCGGCTCCC GAGGAAGGTG ATGGACGCAA AGAAACTGGC CAGCCTGCTG 
CGTGGCGGGC CTGGGGGACC CTTGGTCATC GACAGCCGGT CCTTCGTGGA GTATAACAGC 
TGCCACGTGC TGAGCTCTGT GAATATCTGC TGTTCAAAGC TGGTGAAGCG GCGCCTTCAG 
CAGGGAAAAG TGACAATTGC TGAGCTTATC CAGCCTGCTA CACGGAGCCA GGTGGATGCC 
ACAGAACCAC AGGATGTAGT GGTGTATGAC CAGAGCACAC GAGATGCCAG CGTGCTGGCA 
GCAGACAGCT TCCTGTCCAT CCTGCTCAGC AAGCTGGACG GCTGCTTCGA CAGTGTGGCC 
ATCCTCACAG GAGGCTTCGC CACCTTCTCC TCCTGCTTCC CTGGCCTCTG TGAGGGCAAG 
CCTGCCACTC TACCGTCCAT GAGCCTCTCT CAGCCCTGCC TGCCTGTGCC CAGTGTTGGC 
CTGACCCGAA TCCTGCCTCA CCTCTACCTG GGCTCTCAGA AAGATGTCTT GAACAAGGAT 
CTGATGACCC AAAACGGAAT AAGCTATGTC CTCAATGCCA GCAACTCCTG CCCTAAACCG 
GACTTCATCT GTGAGAGCCG TTTCATGCGT ATCCCCATCA ATGACAACTA CTGTGAAAAG 
CTGCTGCCCT GGCTGGACAA GTCCATCGAG TTTATTGATA AAGCCAAGCT GTCCAGCTGC 
CAAGTCATTG TTCACTGTCT GGCTGGCATC TCTCGCTCTG CCACCATTGC CATCGCGTAC 
ATCATGAAAA CCATGGGCAT GTCTTCTGAC GACGCATACA GGTTTGTGAA GGATCGGCGC 
CCCTCCATCT CGCCCAACTT CAACTTCCTG GGCCAGTTGC TGGAGTATGA GAGGAGTCTG 
AAGCTGCTGG CTGCCCTGCA GACTGATGGA CCTCACTTGG GGACCCCTGA GCCCCTCATG 
GGCCCGGCAG CAGGCATCCC ACTGCCCCGG CTGCCACCAT CTACCTCAGA GAGCGCTGCC 
ACTGGGAGCG AGGCAGCCAC CGCAGCCAGG GAGGGCAGCC CAAGTGCTGG AGGGGATGCT 
CCGATCCCCA GCACAGCTCC AGCCACCAGC GCGCTGCAGC AGGGCCTGCG TGGCCTGCAC 
CTCTCCTCTG ACCGCCTCCA GGACACCAAC CGCCTCAAGC GTTCCTTTTC CCTGGACATC 
AAGTCGGCCT ATGCACCCAG CAGGAGGCCC GACTTTCCCG GCCCACCCGA CCCCGGTGAA 
GCCCCGAAGC TCTGCAAGCT GGACAGCCCG TCTGGGGGCA CACTGGGCCT GCCCTCGCCC 
AGCCCAGACA GCCCGGACTC CGTTCCAGAG TGCCGCCCAC GACCCCGCCG GCGACGCCCC 
CCGGCTAGTT CGCCTGCCCG CTCCCCCGCG CATGGTCTGG GCCTGAACTT TGGAGACACG 
GCCCGGCAGA CTCCACGGCA CGGCCTCTCG GCCCTGTCGG CGCCCGGGCT GCCTGGCCCT 
GGCCAGCCGG CTGGCCCCGG GGGCTGGGTG CCGCCACTGG ACTCCCCAGG CACACCGTCG 
CCCGACGGCC CCTGGTGCTT CAGCCCCGAG GGCGCGCAGG GTCCAGGCGC TGTGTTCTCC 
GCCTTTGGCC GGGTAAGTGC AGGCGCACCT GGACCCGGTA ACAGCAGCAG CAGCGGTGGT 
GGTGGTGGTG GTGGTGGCGG CGGCGGCGGC GGCGGCGGCG GCGGCGGCAG CAGCAGCAGC 
AACAGCAGCA GCAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGTAG TAGTAGTAGT 
GACCTGCGGA GGCGGGATGT GCGGACCGGC TGGCCCGAGG AGCCTGCTGC AGATGCACAG 
TTCAAGAGGC GCAGCTGCCA GATGGAGTTC GAAGAGGGCA TGGTGGAGGG GCGGGCACGT 
GGCGAGGAGC TGGCAGCCCT GGGCAAGCAA ACCAGCTTCT CTGGCAGCGT GGAGGTCATC 
GAAGTATCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011240291.1
CDS	174..2165
Translation	MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSCHVLSSVNICCSKLVKRRLQQGKVTIAELIQPATRSQVDATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCEGKPATLPSMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRIPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAALQTDGPHLGTPEPLMGPAAGIPLPRLPPSTSESAATGSEAATAAREGSPSAGGDAPIPSTAPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDFPGPPDPGEAPKLCKLDSPSGGTLGLPSPSPDSPDSVPECRPRPRRRRPPASSPARSPAHGLGLNFGDTARQTPRHGLSALSAPGLPGPGQPAGPGGWVPPLDSPGTPSPDGPWCFSPEGAQGPGAVFSAFGRVSAGAPGPGNSSSSGGGGGGGGGGGGGGGGGGSSSSNSSSSSSSSSSSSSSSSSSSDLRRRDVRTGWPEEPAADAQFKRRSCQMEFEEGMVEGRARGEELAALGKQTSFSGSVEVIEVS

Target ORF information:

RefSeq Version	XM_011241989.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual specificity phosphatase 8 (Dusp8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011241989.2

ORF Insert Sequence:

ATGGCTGGGG ATCGGCTCCC GAGGAAGGTG ATGGACGCAA AGAAACTGGC CAGCCTGCTG 
CGTGGCGGGC CTGGGGGACC CTTGGTCATC GACAGCCGGT CCTTCGTGGA GTATAACAGC 
TGCCACGTGC TGAGCTCTGT GAATATCTGC TGTTCAAAGC TGGTGAAGCG GCGCCTTCAG 
CAGGGAAAAG TGACAATTGC TGAGCTTATC CAGCCTGCTA CACGGAGCCA GGTGGATGCC 
ACAGAACCAC AGGATGTAGT GGTGTATGAC CAGAGCACAC GAGATGCCAG CGTGCTGGCA 
GCAGACAGCT TCCTGTCCAT CCTGCTCAGC AAGCTGGACG GCTGCTTCGA CAGTGTGGCC 
ATCCTCACAG GAGGCTTCGC CACCTTCTCC TCCTGCTTCC CTGGCCTCTG TGAGGGCAAG 
CCTGCCACTC TACCGTCCAT GAGCCTCTCT CAGCCCTGCC TGCCTGTGCC CAGTGTTGGC 
CTGACCCGAA TCCTGCCTCA CCTCTACCTG GGCTCTCAGA AAGATGTCTT GAACAAGGAT 
CTGATGACCC AAAACGGAAT AAGCTATGTC CTCAATGCCA GCAACTCCTG CCCTAAACCG 
GACTTCATCT GTGAGAGCCG TTTCATGCGT ATCCCCATCA ATGACAACTA CTGTGAAAAG 
CTGCTGCCCT GGCTGGACAA GTCCATCGAG TTTATTGATA AAGCCAAGCT GTCCAGCTGC 
CAAGTCATTG TTCACTGTCT GGCTGGCATC TCTCGCTCTG CCACCATTGC CATCGCGTAC 
ATCATGAAAA CCATGGGCAT GTCTTCTGAC GACGCATACA GGTTTGTGAA GGATCGGCGC 
CCCTCCATCT CGCCCAACTT CAACTTCCTG GGCCAGTTGC TGGAGTATGA GAGGAGTCTG 
AAGCTGCTGG CTGCCCTGCA GACTGATGGA CCTCACTTGG GGACCCCTGA GCCCCTCATG 
GGCCCGGCAG CAGGCATCCC ACTGCCCCGG CTGCCACCAT CTACCTCAGA GAGCGCTGCC 
ACTGGGAGCG AGGCAGCCAC CGCAGCCAGG GAGGGCAGCC CAAGTGCTGG AGGGGATGCT 
CCGATCCCCA GCACAGCTCC AGCCACCAGC GCGCTGCAGC AGGGCCTGCG TGGCCTGCAC 
CTCTCCTCTG ACCGCCTCCA GGACACCAAC CGCCTCAAGC GTTCCTTTTC CCTGGACATC 
AAGTCGGCCT ATGCACCCAG CAGGAGGCCC GACTTTCCCG GCCCACCCGA CCCCGGTGAA 
GCCCCGAAGC TCTGCAAGCT GGACAGCCCG TCTGGGGGCA CACTGGGCCT GCCCTCGCCC 
AGCCCAGACA GCCCGGACTC CGTTCCAGAG TGCCGCCCAC GACCCCGCCG GCGACGCCCC 
CCGGCTAGTT CGCCTGCCCG CTCCCCCGCG CATGGTCTGG GCCTGAACTT TGGAGACACG 
GCCCGGCAGA CTCCACGGCA CGGCCTCTCG GCCCTGTCGG CGCCCGGGCT GCCTGGCCCT 
GGCCAGCCGG CTGGCCCCGG GGGCTGGGTG CCGCCACTGG ACTCCCCAGG CACACCGTCG 
CCCGACGGCC CCTGGTGCTT CAGCCCCGAG GGCGCGCAGG GTCCAGGCGC TGTGTTCTCC 
GCCTTTGGCC GGGTAAGTGC AGGCGCACCT GGACCCGGTA ACAGCAGCAG CAGCGGTGGT 
GGTGGTGGTG GTGGTGGCGG CGGCGGCGGC GGCGGCGGCG GCGGCGGCAG CAGCAGCAGC 
AACAGCAGCA GCAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGTAG TAGTAGTAGT 
GACCTGCGGA GGCGGGATGT GCGGACCGGC TGGCCCGAGG AGCCTGCTGC AGATGCACAG 
TTCAAGAGGC GCAGCTGCCA GATGGAGTTC GAAGAGGGCA TGGTGGAGGG GCGGGCACGT 
GGCGAGGAGC TGGCAGCCCT GGGCAAGCAA ACCAGCTTCT CTGGCAGCGT GGAGGTCATC 
GAAGTATCGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

DUSP8 Regulates Cardiac Ventricular Remodeling by Altering ERK1/2 Signaling.
Circulation research119(2)249-60(2016 Jul)
Liu R,van Berlo JH,York AJ,Vagnozzi RJ,Maillet M,Molkentin JD

Loss of ATF2 function leads to cranial motoneuron degeneration during embryonic mouse development.
PloS one6(4)e19090(2011 Apr)
Ackermann J,Ashton G,Lyons S,James D,Hornung JP,Jones N,Breitwieser W

Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells.
Genes & development21(16)2069-82(2007 Aug)
Breitwieser W,Lyons S,Flenniken AM,Ashton G,Bruder G,Willington M,Lacaud G,Kouskoff V,Jones N

A growing family of dual specificity phosphatases with low molecular masses.
Journal of biochemistry130(1)133-40(2001 Jul)
Aoki N,Aoyama K,Nagata M,Matsuda T

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Dusp8 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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