Ninj1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ninj1
Entrez Gene ID	18081
Full Name	ninjurin 1
Synonyms	AU024536
General protein information	Preferred Names ninjurin 1 Names ninjurin-1 nerve injury-induced protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 A5

mRNA and Protein(s)

mRNA	Protein	Name
NM_013610.2	NP_038638.1	ninjurin-1
NM_013610.3	NP_038638.1	ninjurin-1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	NINJ1	XP_853215.2
Danio rerio (zebrafish)	LOC100150223	XP_001919024.1
Xenopus tropicalis (tropical clawed frog)	ninj1	NP_001008021.2
	NINJ1	XP_001108521.2
Bos taurus (cattle)	NINJ1	NP_001033171.1
Homo sapiens (human)	NINJ1	NP_004139.2
Gallus gallus (chicken)	NINJ1	NP_001264806.1
Pan troglodytes (chimpanzee)	NINJ1	XP_003312226.1
Mus musculus (house mouse)	Ninj1	NP_038638.1
Rattus norvegicus (Norway rat)	Ninj1	NP_036999.1

Gene Ontology
Bibliography

Related articles in PubMed

Ninjurin 1 has two opposing functions in tumorigenesis in a p53-dependent manner.
Yang HJ, Zhang J, Yan W, Cho SJ, Lucchesi C, Chen M, Huang EC, Scoumanne A, Zhang W, Chen X
Proceedings of the National Academy of Sciences of the United States of America114(43)11500-11505(2017 Oct)

Ninjurin1 Assembles Into a Homomeric Protein Complex Maintained by N-linked Glycosylation.
Bae SJ, Shin MW, Kim RH, Shin D, Son T, Wee HJ, Kim KW
Journal of cellular biochemistry118(8)2219-2230(2017 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that Ninj1 assembles into a homomeric protein complex and that N-glycosylation is a prerequisite for Ninj1 homomer assembly.
Title: Ninjurin1 Assembles Into a Homomeric Protein Complex Maintained by N-linked Glycosylation.

Ninjurin1 is a key regulator molecule for macrophage migration and Tumor-associated macrophages (TAM) mediated tumorigenesis in vivo.
Title: Ninjurin1 inhibits colitis-mediated colon cancer development and growth by suppression of macrophage infiltration through repression of FAK signaling.

Ninj1 modulates TLR4 signaling, which itself plays a major role in systemic inflammatory response syndrome and sepsis.
Title: Contribution of Ninjurin1 to Toll-like receptor 4 signaling and systemic inflammation.

Ninj1 negatively regulates the formation of neovessels, that is, the EC-tube, by reducing the trophic effects of capillary pericytes.
Title: Ninjurin1 is a novel factor to regulate angiogenesis through the function of pericytes.

Inhibition of Ninjurin 1 restores erectile function through dual angiogenic and neurotrophic effects in the diabetic mouse.
Title: Inhibition of Ninjurin 1 restores erectile function through dual angiogenic and neurotrophic effects in the diabetic mouse.

The following Ninj1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ninj1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu17723	NM_013610.3 Latest version!	Mus musculus ninjurin 1 (Ninj1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
View Old Accession Versions >>
OMu17723	NM_013610.2	Mus musculus ninjurin 1 (Ninj1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ninj1 ( NM_013610.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038638.1 Mus musculus ninjurin 1 (Ninj1), mRNA.

Price & Availability↑

CloneID	OMu17723
Clone ID Related Accession (Same CDS sequence)	NM_013610.2 , NM_013610.3
Accession Version	NM_013610.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-28
Organism	Mus musculus(house mouse)
Product	ninjurin-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC140284.3. On Nov 17, 2006 this sequence version replaced NM_013610.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U91513.1, AK155741.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGAGTCGG GCACTGAGGA GTATGAGCTC AACGGCGACC TGCGCCCGGG CTCCCCCGGT 
TCCCCCGACG CCTTGCCACC CCGCTGGGGT TTGCGGAACC GGCCCATCAA TGTAAACCAT 
TATGCCAACA AGAAGAGCGC TGCGGAGAGC ATGCTGGACA TCGCGCTGCT CATGGCCAAC 
GCGTCGCAGC TGAAGGCCGT GGTGGAGCAG GGCAATGATT TCGCCTTCTT CGTGCCCCTT 
GTGGTCCTCA TCTCTATCTC CCTCGTGCTG CAGATAGGAG TGGGCGTGCT GCTCATCTTC 
CTGGTCAAGT ATGACCTCAA CAACCCGGCC AAGCACGCCA AGCTGGACTT TCTTAACAAC 
CTGGCCACGG GACTGGTTTT CATCATCGTC GTGGTCAACA TCTTCATTAC GGCCTTCGGG 
GTCCAGAAGC CTGTAATGGA CGTGGCGCCC CGGCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038638.1
CDS	17..475
Translation	MESGTEEYELNGDLRPGSPGSPDALPPRWGLRNRPINVNHYANKKSAAESMLDIALLMANASQLKAVVEQGNDFAFFVPLVVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNNLATGLVFIIVVVNIFITAFGVQKPVMDVAPRQ

Target ORF information:

RefSeq Version	NM_013610.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ninjurin 1 (Ninj1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013610.2

ORF Insert Sequence:

ATGGAGTCGG GCACTGAGGA GTATGAGCTC AACGGCGACC TGCGCCCGGG CTCCCCCGGT 
TCCCCCGACG CCTTGCCACC CCGCTGGGGT TTGCGGAACC GGCCCATCAA TGTAAACCAT 
TATGCCAACA AGAAGAGCGC TGCGGAGAGC ATGCTGGACA TCGCGCTGCT CATGGCCAAC 
GCGTCGCAGC TGAAGGCCGT GGTGGAGCAG GGCAATGATT TCGCCTTCTT CGTGCCCCTT 
GTGGTCCTCA TCTCTATCTC CCTCGTGCTG CAGATAGGAG TGGGCGTGCT GCTCATCTTC 
CTGGTCAAGT ATGACCTCAA CAACCCGGCC AAGCACGCCA AGCTGGACTT TCTTAACAAC 
CTGGCCACGG GACTGGTTTT CATCATCGTC GTGGTCAACA TCTTCATTAC GGCCTTCGGG 
GTCCAGAAGC CTGTAATGGA CGTGGCGCCC CGGCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ninj1 ( NM_013610.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038638.1 Mus musculus ninjurin 1 (Ninj1), mRNA.

Price & Availability↑

CloneID	OMu17723
Clone ID Related Accession (Same CDS sequence)	NM_013610.2 , NM_013610.3
Accession Version	NM_013610.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-26
Organism	Mus musculus(house mouse)
Product	ninjurin-1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK159111.1 and BB756836.1. On Feb 5, 2019 this sequence version replaced NM_013610.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3224855.8693.1, U91513.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGAGTCGG GCACTGAGGA GTATGAGCTC AACGGCGACC TGCGCCCGGG CTCCCCCGGT 
TCCCCCGACG CCTTGCCACC CCGCTGGGGT TTGCGGAACC GGCCCATCAA TGTAAACCAT 
TATGCCAACA AGAAGAGCGC TGCGGAGAGC ATGCTGGACA TCGCGCTGCT CATGGCCAAC 
GCGTCGCAGC TGAAGGCCGT GGTGGAGCAG GGCAATGATT TCGCCTTCTT CGTGCCCCTT 
GTGGTCCTCA TCTCTATCTC CCTCGTGCTG CAGATAGGAG TGGGCGTGCT GCTCATCTTC 
CTGGTCAAGT ATGACCTCAA CAACCCGGCC AAGCACGCCA AGCTGGACTT TCTTAACAAC 
CTGGCCACGG GACTGGTTTT CATCATCGTC GTGGTCAACA TCTTCATTAC GGCCTTCGGG 
GTCCAGAAGC CTGTAATGGA CGTGGCGCCC CGGCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038638.1
CDS	35..493
Translation	MESGTEEYELNGDLRPGSPGSPDALPPRWGLRNRPINVNHYANKKSAAESMLDIALLMANASQLKAVVEQGNDFAFFVPLVVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNNLATGLVFIIVVVNIFITAFGVQKPVMDVAPRQ

Target ORF information:

RefSeq Version	NM_013610.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ninjurin 1 (Ninj1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013610.3

ORF Insert Sequence:

ATGGAGTCGG GCACTGAGGA GTATGAGCTC AACGGCGACC TGCGCCCGGG CTCCCCCGGT 
TCCCCCGACG CCTTGCCACC CCGCTGGGGT TTGCGGAACC GGCCCATCAA TGTAAACCAT 
TATGCCAACA AGAAGAGCGC TGCGGAGAGC ATGCTGGACA TCGCGCTGCT CATGGCCAAC 
GCGTCGCAGC TGAAGGCCGT GGTGGAGCAG GGCAATGATT TCGCCTTCTT CGTGCCCCTT 
GTGGTCCTCA TCTCTATCTC CCTCGTGCTG CAGATAGGAG TGGGCGTGCT GCTCATCTTC 
CTGGTCAAGT ATGACCTCAA CAACCCGGCC AAGCACGCCA AGCTGGACTT TCTTAACAAC 
CTGGCCACGG GACTGGTTTT CATCATCGTC GTGGTCAACA TCTTCATTAC GGCCTTCGGG 
GTCCAGAAGC CTGTAATGGA CGTGGCGCCC CGGCAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ninjurin 1 has two opposing functions in tumorigenesis in a p53-dependent manner.
Proceedings of the National Academy of Sciences of the United States of America114(43)11500-11505(2017 Oct)
Yang HJ,Zhang J,Yan W,Cho SJ,Lucchesi C,Chen M,Huang EC,Scoumanne A,Zhang W,Chen X

Ninjurin1 Assembles Into a Homomeric Protein Complex Maintained by N-linked Glycosylation.
Journal of cellular biochemistry118(8)2219-2230(2017 Aug)
Bae SJ,Shin MW,Kim RH,Shin D,Son T,Wee HJ,Kim KW

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Ninj1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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