Gene Symbol | Mitf |
Entrez Gene ID | 17342 |
Full Name | melanogenesis associated transcription factor |
Synonyms | BCC2,Bhlhe32,Gsfbcc2,Vitiligo,Wh,bw,mi,vit |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome | |
Summary | This transcription factor serves at a critical point between extracellular signaling and downstream targets in cell specification in early eye and neural crest development. Mutant alleles have been identified that generate distinct phenotypes. Some of these alleles are being used to model the human diseases Waardenburg syndrome IIa and Tietz syndrome. [provided by RefSeq, Jul 2008]. |