Mdm4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mdm4
Entrez Gene ID	17248
Full Name	transformed mouse 3T3 cell double minute 4
Synonyms	4933417N07Rik,AA414968,AL023055,AU018793,AU021806,C85810,Mdmx
General protein information	Preferred Names transformed mouse 3T3 cell double minute 4 Names protein Mdm4 double minute 4 protein mdm2-like p53-binding protein p53-binding protein Mdm4 protein Mdmx
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 E4\|1 57.75 cM
Summary	This gene encodes a protein that has been shown to negatively regulate the activity of the tumor suppressor protein p53. Homozygous knockout mice exhibit embryonic lethality as a result of p53-dependent apoptosis and cell cycle arrest. Amplification of this gene or overexpression of the encoded protein has been linked to a range of human cancers. A pseudogene has been identified on the X chromosome. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001302803.1	NP_001289732.1	protein Mdm4 isoform 2
XM_006529233.2	XP_006529296.1	protein Mdm4 isoform X1
NM_001302802.1	NP_001289731.1	protein Mdm4 isoform 1
NM_008575.4	NP_032601.2	protein Mdm4 isoform 2
NM_001302804.1	NP_001289733.1	protein Mdm4 isoform 3
NM_001302801.1	NP_001289730.1	protein Mdm4 isoform 1
XM_006529233.3	XP_006529296.1	protein Mdm4 isoform X1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	MDM4	XP_004934981.1
Xenopus tropicalis (tropical clawed frog)	mdm4	NP_001135717.1
Rattus norvegicus (Norway rat)	Mdm4	NP_001012026.1
Canis lupus familiaris (dog)	MDM4	XP_005640824.1
Bos taurus (cattle)	MDM4	NP_001039634.1
Mus musculus (house mouse)	Mdm4	NP_032601.2
Danio rerio (zebrafish)	mdm4	NP_997897.1
Pan troglodytes (chimpanzee)	MDM4	XP_003949728.1
	MDM4	XP_001097488.2
Homo sapiens (human)	MDM4	NP_002384.2

Gene Ontology
Bibliography

Related articles in PubMed

Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery.
Bezzi M, Teo SX, Muller J, Mok WC, Sahu SK, Vardy LA, Bonday ZQ, Guccione E
Genes & development27(17)1903-16(2013 Sep)

MDM2, MDMX and p53 in oncogenesis and cancer therapy.
Wade M, Li YC, Wahl GM
Nature reviews. Cancer13(2)83-96(2013 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings suggest that Mdm2 splice isoforms may play critical roles in the regulatory loop of p53/Mdm2-Mdm4 via a RING domain-mediated biochemical mechanism.
Title: Mdm2 Splice isoforms regulate the p53/Mdm2/Mdm4 regulatory circuit via RING domain-mediated ubiquitination of p53 and Mdm4.

both MDM2 and MDMX deletion-caused pancreatic defects are completely rescued by loss of p53, verifying the crucial role of the MDM2 and/or MDMX in regulating p53 in a spatio-temporal manner during the development, functional maintenance, and related disease progress of endocrine pancreas.
Title: Monitoring p53 by MDM2 and MDMX is required for endocrine pancreas development and function in a spatio-temporal manner.

The p53-null mice with the highest level of Mdm4 tended to have multiple tumours. Mdm4 transgenic mice in various genetic backgrounds shows synergy in tumour development in vivo. Mdm4 may thus serve as a therapeutic target in cancers.
Title: The p53 inhibitor Mdm4 cooperates with multiple genetic lesions in tumourigenesis.

we failed to detect any increase in p53 level in mutant oocytes, nor any other apoptotic marker, introgression of this targeted invalidation in p53-/- mice restored the fertility of females. This study is the first to show that Mdm2, but not Mdm4, has a critical role in oocyte survival and would be involved in premature ovarian insufficiency phenotype.
Title: Loss of oocytes due to conditional ablation of Murine double minute 2 (Mdm2) gene is p53-dependent and results in female sterility.

Data show that the Mdm4-p73 axis cannot override the dominant role of p53 in development and tumorigenesis and that Mdm4 and p73 interaction during development and tumorigenesis suggests new insight into the role of p53 family members.
Title: p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis.

The following Mdm4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mdm4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu22251	NM_008575.4 Latest version!	Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu22251	NM_001302803.1 Latest version!	Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu27986	NM_001302801.1 Latest version!	Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu27986	NM_001302802.1 Latest version!	Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu68193	NM_001302804.1 Latest version!	Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu27986	XM_006529233.3 Latest version!	Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OMu27986	XM_006529233.2	Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mdm4 ( NM_001302803.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001289732.1 Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu22251
Clone ID Related Accession (Same CDS sequence)	NM_001302803.1 , NM_008575.4
Accession Version	NM_001302803.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	protein Mdm4 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CJ101093.1, AK017719.1, AK083349.1, AK043359.1, AK046448.1 and BC058680.1. Transcript Variant: This variant (4) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The resulting isoform (2) is shorter compared to isoform 1. Both variants 3 and 4 encode the same isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164141 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACATCAC ATTCCACCTC GGCCCAGTGT TCAGCATCTG ACAGTGCTTG CAGAATTTCT 
TCGGAACAAA TTAGTCAGGT GCGGCCAAAA CTGCAGCTTT TGAAGATTTT GCATGCAGCA 
GGTGCGCAGG GGGAAGTATT CACCATGAAA GAGGTAATGC ACTATCTAGG CCAGTATATA 
ATGGTGAAGC AGCTCTATGA TCAACAGGAG CAACATATGG TATACTGTGG TGGAGATCTT 
TTGGGAGATC TACTTGGATG TCAGAGCTTT TCTGTGAAAG ATCCAAGCCC TCTCTATGAC 
ATGCTAAGAA AGAATCTTGT TACATCAGCT TCTATTAACA CAGATGCTGC TCAGACTCTC 
GCTCTCGCAC AGGATCACAC TATGGATTTT CCAAGTCAAG ACCGACTGAA GCACGGTGCA 
ACAGAATACT CCAATCCCAG AAAAAGAACT GAAGAAGAGG ATACTCACAC ACTGCCTACC 
TCACGACATA AATGCAGAGA CTCCAGAGCA GATGAAGACT TGATAGAACA TTTATCTCAA 
GATGAGACAT CTAGGCTTGA CCTTGATTTT GAGGAGTGGG ACGTTGCTGG CCTGCCTTGG 
TGGTTTCTAG GGAATTTGAG AAACAACTGT ATTCCTAAAA GTAATGGCTC AACTGATTTA 
CAGACAAATC AGGATATAGG TACTGCCATT GTTTCAGACA CTACGGATGA TTTGTGGTTT 
TTAAATGAGA CCGTGTCAGA GCAATTAGGT GTTGGAATAA AAGTTGAAGC TGCTAATTCT 
GAGCAAACAA GTGAAGTAGG GAAAACAAGT AACAAGAAGA CGGTGGAGGT GGGAAAGGAT 
GATGATCTTG AGGACTCCAG GTCCTTGAGC GATGATACTG ACGTGGAACT TACCTCTGAG 
GATGAGTGGC AGTGTACGGA ATGCAAGAAG TTTAATTCTC CAAGCAAGAG GTACTGTTTT 
CGTTGCTGGG CCTTGAGAAA GGATTGGTAT TCGGATTGTT CTAAATTAAC TCATTCCCTA 
TCTACATCTA ATATTACTGC CATACCTGAA AAGAAGGACA ATGAAGGAAT TGATGTTCCC 
GATTGTAGGA GAACCATTTC AGCTCCTGTT GTTAGGCCTA AAGATGGATA TTTAAAGGAG 
GAAAAGCCCA GGTTTGACCC TTGCAACTCA GTGGGATTTT TGGATTTGGC TCATAGTTCT 
GAAAGCCAGG AGATCATCTC AAGCGCGAGA GAACAAACAG ATATTTTTTC TGAGCAGAAA 
GCTGAAACAG AAAGTATGGA AGATTTCCAG AATGTCTTGA AGCCGTGTAG CTTATGTGAA 
AAAAGGCCTC GGGATGGGAA CATTATTCAT GGGAAGACGA GCCATCTGAC GACATGTTTC 
CACTGTGCCA GGAGACTGAA GAAGTCTGGG GCTTCGTGTC CTGCTTGTAA GAAAGAGATT 
CAGTTGGTTA TTAAAGTTTT TATAGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289732.1
CDS	200..1669
Translation	MTSHSTSAQCSASDSACRISSEQISQVRPKLQLLKILHAAGAQGEVFTMKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGDLLGCQSFSVKDPSPLYDMLRKNLVTSASINTDAAQTLALAQDHTMDFPSQDRLKHGATEYSNPRKRTEEEDTHTLPTSRHKCRDSRADEDLIEHLSQDETSRLDLDFEEWDVAGLPWWFLGNLRNNCIPKSNGSTDLQTNQDIGTAIVSDTTDDLWFLNETVSEQLGVGIKVEAANSEQTSEVGKTSNKKTVEVGKDDDLEDSRSLSDDTDVELTSEDEWQCTECKKFNSPSKRYCFRCWALRKDWYSDCSKLTHSLSTSNITAIPEKKDNEGIDVPDCRRTISAPVVRPKDGYLKEEKPRFDPCNSVGFLDLAHSSESQEIISSAREQTDIFSEQKAETESMEDFQNVLKPCSLCEKRPRDGNIIHGKTSHLTTCFHCARRLKKSGASCPACKKEIQLVIKVFIA

Target ORF information:

RefSeq Version	NM_001302803.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302803.1

ORF Insert Sequence:

ATGACATCAC ATTCCACCTC GGCCCAGTGT TCAGCATCTG ACAGTGCTTG CAGAATTTCT 
TCGGAACAAA TTAGTCAGGT GCGGCCAAAA CTGCAGCTTT TGAAGATTTT GCATGCAGCA 
GGTGCGCAGG GGGAAGTATT CACCATGAAA GAGGTAATGC ACTATCTAGG CCAGTATATA 
ATGGTGAAGC AGCTCTATGA TCAACAGGAG CAACATATGG TATACTGTGG TGGAGATCTT 
TTGGGAGATC TACTTGGATG TCAGAGCTTT TCTGTGAAAG ATCCAAGCCC TCTCTATGAC 
ATGCTAAGAA AGAATCTTGT TACATCAGCT TCTATTAACA CAGATGCTGC TCAGACTCTC 
GCTCTCGCAC AGGATCACAC TATGGATTTT CCAAGTCAAG ACCGACTGAA GCACGGTGCA 
ACAGAATACT CCAATCCCAG AAAAAGAACT GAAGAAGAGG ATACTCACAC ACTGCCTACC 
TCACGACATA AATGCAGAGA CTCCAGAGCA GATGAAGACT TGATAGAACA TTTATCTCAA 
GATGAGACAT CTAGGCTTGA CCTTGATTTT GAGGAGTGGG ACGTTGCTGG CCTGCCTTGG 
TGGTTTCTAG GGAATTTGAG AAACAACTGT ATTCCTAAAA GTAATGGCTC AACTGATTTA 
CAGACAAATC AGGATATAGG TACTGCCATT GTTTCAGACA CTACGGATGA TTTGTGGTTT 
TTAAATGAGA CCGTGTCAGA GCAATTAGGT GTTGGAATAA AAGTTGAAGC TGCTAATTCT 
GAGCAAACAA GTGAAGTAGG GAAAACAAGT AACAAGAAGA CGGTGGAGGT GGGAAAGGAT 
GATGATCTTG AGGACTCCAG GTCCTTGAGC GATGATACTG ACGTGGAACT TACCTCTGAG 
GATGAGTGGC AGTGTACGGA ATGCAAGAAG TTTAATTCTC CAAGCAAGAG GTACTGTTTT 
CGTTGCTGGG CCTTGAGAAA GGATTGGTAT TCGGATTGTT CTAAATTAAC TCATTCCCTA 
TCTACATCTA ATATTACTGC CATACCTGAA AAGAAGGACA ATGAAGGAAT TGATGTTCCC 
GATTGTAGGA GAACCATTTC AGCTCCTGTT GTTAGGCCTA AAGATGGATA TTTAAAGGAG 
GAAAAGCCCA GGTTTGACCC TTGCAACTCA GTGGGATTTT TGGATTTGGC TCATAGTTCT 
GAAAGCCAGG AGATCATCTC AAGCGCGAGA GAACAAACAG ATATTTTTTC TGAGCAGAAA 
GCTGAAACAG AAAGTATGGA AGATTTCCAG AATGTCTTGA AGCCGTGTAG CTTATGTGAA 
AAAAGGCCTC GGGATGGGAA CATTATTCAT GGGAAGACGA GCCATCTGAC GACATGTTTC 
CACTGTGCCA GGAGACTGAA GAAGTCTGGG GCTTCGTGTC CTGCTTGTAA GAAAGAGATT 
CAGTTGGTTA TTAAAGTTTT TATAGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mdm4 ( NM_008575.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032601.2 Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu22251
Clone ID Related Accession (Same CDS sequence)	NM_001302803.1 , NM_008575.4
Accession Version	NM_008575.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	protein Mdm4 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CJ101093.1, AK083349.1, AK043359.1, AK046448.1 and BC058680.1. On Nov 18, 2014 this sequence version replaced NM_008575.3. Transcript Variant: This variant (3) contains an alternate exon in the 5' UTR and uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The resulting isoform (2) is shorter compared to isoform 1. Both variants 3 and 4 encode the same isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164141, SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACATCAC ATTCCACCTC GGCCCAGTGT TCAGCATCTG ACAGTGCTTG CAGAATTTCT 
TCGGAACAAA TTAGTCAGGT GCGGCCAAAA CTGCAGCTTT TGAAGATTTT GCATGCAGCA 
GGTGCGCAGG GGGAAGTATT CACCATGAAA GAGGTAATGC ACTATCTAGG CCAGTATATA 
ATGGTGAAGC AGCTCTATGA TCAACAGGAG CAACATATGG TATACTGTGG TGGAGATCTT 
TTGGGAGATC TACTTGGATG TCAGAGCTTT TCTGTGAAAG ATCCAAGCCC TCTCTATGAC 
ATGCTAAGAA AGAATCTTGT TACATCAGCT TCTATTAACA CAGATGCTGC TCAGACTCTC 
GCTCTCGCAC AGGATCACAC TATGGATTTT CCAAGTCAAG ACCGACTGAA GCACGGTGCA 
ACAGAATACT CCAATCCCAG AAAAAGAACT GAAGAAGAGG ATACTCACAC ACTGCCTACC 
TCACGACATA AATGCAGAGA CTCCAGAGCA GATGAAGACT TGATAGAACA TTTATCTCAA 
GATGAGACAT CTAGGCTTGA CCTTGATTTT GAGGAGTGGG ACGTTGCTGG CCTGCCTTGG 
TGGTTTCTAG GGAATTTGAG AAACAACTGT ATTCCTAAAA GTAATGGCTC AACTGATTTA 
CAGACAAATC AGGATATAGG TACTGCCATT GTTTCAGACA CTACGGATGA TTTGTGGTTT 
TTAAATGAGA CCGTGTCAGA GCAATTAGGT GTTGGAATAA AAGTTGAAGC TGCTAATTCT 
GAGCAAACAA GTGAAGTAGG GAAAACAAGT AACAAGAAGA CGGTGGAGGT GGGAAAGGAT 
GATGATCTTG AGGACTCCAG GTCCTTGAGC GATGATACTG ACGTGGAACT TACCTCTGAG 
GATGAGTGGC AGTGTACGGA ATGCAAGAAG TTTAATTCTC CAAGCAAGAG GTACTGTTTT 
CGTTGCTGGG CCTTGAGAAA GGATTGGTAT TCGGATTGTT CTAAATTAAC TCATTCCCTA 
TCTACATCTA ATATTACTGC CATACCTGAA AAGAAGGACA ATGAAGGAAT TGATGTTCCC 
GATTGTAGGA GAACCATTTC AGCTCCTGTT GTTAGGCCTA AAGATGGATA TTTAAAGGAG 
GAAAAGCCCA GGTTTGACCC TTGCAACTCA GTGGGATTTT TGGATTTGGC TCATAGTTCT 
GAAAGCCAGG AGATCATCTC AAGCGCGAGA GAACAAACAG ATATTTTTTC TGAGCAGAAA 
GCTGAAACAG AAAGTATGGA AGATTTCCAG AATGTCTTGA AGCCGTGTAG CTTATGTGAA 
AAAAGGCCTC GGGATGGGAA CATTATTCAT GGGAAGACGA GCCATCTGAC GACATGTTTC 
CACTGTGCCA GGAGACTGAA GAAGTCTGGG GCTTCGTGTC CTGCTTGTAA GAAAGAGATT 
CAGTTGGTTA TTAAAGTTTT TATAGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032601.2
CDS	278..1747
Translation	MTSHSTSAQCSASDSACRISSEQISQVRPKLQLLKILHAAGAQGEVFTMKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGDLLGCQSFSVKDPSPLYDMLRKNLVTSASINTDAAQTLALAQDHTMDFPSQDRLKHGATEYSNPRKRTEEEDTHTLPTSRHKCRDSRADEDLIEHLSQDETSRLDLDFEEWDVAGLPWWFLGNLRNNCIPKSNGSTDLQTNQDIGTAIVSDTTDDLWFLNETVSEQLGVGIKVEAANSEQTSEVGKTSNKKTVEVGKDDDLEDSRSLSDDTDVELTSEDEWQCTECKKFNSPSKRYCFRCWALRKDWYSDCSKLTHSLSTSNITAIPEKKDNEGIDVPDCRRTISAPVVRPKDGYLKEEKPRFDPCNSVGFLDLAHSSESQEIISSAREQTDIFSEQKAETESMEDFQNVLKPCSLCEKRPRDGNIIHGKTSHLTTCFHCARRLKKSGASCPACKKEIQLVIKVFIA

Target ORF information:

RefSeq Version	NM_008575.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008575.4

ORF Insert Sequence:

ATGACATCAC ATTCCACCTC GGCCCAGTGT TCAGCATCTG ACAGTGCTTG CAGAATTTCT 
TCGGAACAAA TTAGTCAGGT GCGGCCAAAA CTGCAGCTTT TGAAGATTTT GCATGCAGCA 
GGTGCGCAGG GGGAAGTATT CACCATGAAA GAGGTAATGC ACTATCTAGG CCAGTATATA 
ATGGTGAAGC AGCTCTATGA TCAACAGGAG CAACATATGG TATACTGTGG TGGAGATCTT 
TTGGGAGATC TACTTGGATG TCAGAGCTTT TCTGTGAAAG ATCCAAGCCC TCTCTATGAC 
ATGCTAAGAA AGAATCTTGT TACATCAGCT TCTATTAACA CAGATGCTGC TCAGACTCTC 
GCTCTCGCAC AGGATCACAC TATGGATTTT CCAAGTCAAG ACCGACTGAA GCACGGTGCA 
ACAGAATACT CCAATCCCAG AAAAAGAACT GAAGAAGAGG ATACTCACAC ACTGCCTACC 
TCACGACATA AATGCAGAGA CTCCAGAGCA GATGAAGACT TGATAGAACA TTTATCTCAA 
GATGAGACAT CTAGGCTTGA CCTTGATTTT GAGGAGTGGG ACGTTGCTGG CCTGCCTTGG 
TGGTTTCTAG GGAATTTGAG AAACAACTGT ATTCCTAAAA GTAATGGCTC AACTGATTTA 
CAGACAAATC AGGATATAGG TACTGCCATT GTTTCAGACA CTACGGATGA TTTGTGGTTT 
TTAAATGAGA CCGTGTCAGA GCAATTAGGT GTTGGAATAA AAGTTGAAGC TGCTAATTCT 
GAGCAAACAA GTGAAGTAGG GAAAACAAGT AACAAGAAGA CGGTGGAGGT GGGAAAGGAT 
GATGATCTTG AGGACTCCAG GTCCTTGAGC GATGATACTG ACGTGGAACT TACCTCTGAG 
GATGAGTGGC AGTGTACGGA ATGCAAGAAG TTTAATTCTC CAAGCAAGAG GTACTGTTTT 
CGTTGCTGGG CCTTGAGAAA GGATTGGTAT TCGGATTGTT CTAAATTAAC TCATTCCCTA 
TCTACATCTA ATATTACTGC CATACCTGAA AAGAAGGACA ATGAAGGAAT TGATGTTCCC 
GATTGTAGGA GAACCATTTC AGCTCCTGTT GTTAGGCCTA AAGATGGATA TTTAAAGGAG 
GAAAAGCCCA GGTTTGACCC TTGCAACTCA GTGGGATTTT TGGATTTGGC TCATAGTTCT 
GAAAGCCAGG AGATCATCTC AAGCGCGAGA GAACAAACAG ATATTTTTTC TGAGCAGAAA 
GCTGAAACAG AAAGTATGGA AGATTTCCAG AATGTCTTGA AGCCGTGTAG CTTATGTGAA 
AAAAGGCCTC GGGATGGGAA CATTATTCAT GGGAAGACGA GCCATCTGAC GACATGTTTC 
CACTGTGCCA GGAGACTGAA GAAGTCTGGG GCTTCGTGTC CTGCTTGTAA GAAAGAGATT 
CAGTTGGTTA TTAAAGTTTT TATAGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mdm4 ( NM_001302802.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001289731.1 Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu27986
Clone ID Related Accession (Same CDS sequence)	XM_006529233.2 , NM_001302802.1 , NM_001302801.1 , XM_006529233.3
Accession Version	NM_001302802.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	protein Mdm4 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC137948.12, AK139529.1, AK083349.1, AK043359.1, AK046448.1 and BC058680.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACATCAC ATTCCACCTC GGCCCAGTGT TCAGCATCTG ACAGTGCTTG CAGAATTTCT 
TCGGAACAAA TTAGTCAGCA GGTGCGGCCA AAACTGCAGC TTTTGAAGAT TTTGCATGCA 
GCAGGTGCGC AGGGGGAAGT ATTCACCATG AAAGAGGTAA TGCACTATCT AGGCCAGTAT 
ATAATGGTGA AGCAGCTCTA TGATCAACAG GAGCAACATA TGGTATACTG TGGTGGAGAT 
CTTTTGGGAG ATCTACTTGG ATGTCAGAGC TTTTCTGTGA AAGATCCAAG CCCTCTCTAT 
GACATGCTAA GAAAGAATCT TGTTACATCA GCTTCTATTA ACACAGATGC TGCTCAGACT 
CTCGCTCTCG CACAGGATCA CACTATGGAT TTTCCAAGTC AAGACCGACT GAAGCACGGT 
GCAACAGAAT ACTCCAATCC CAGAAAAAGA ACTGAAGAAG AGGATACTCA CACACTGCCT 
ACCTCACGAC ATAAATGCAG AGACTCCAGA GCAGATGAAG ACTTGATAGA ACATTTATCT 
CAAGATGAGA CATCTAGGCT TGACCTTGAT TTTGAGGAGT GGGACGTTGC TGGCCTGCCT 
TGGTGGTTTC TAGGGAATTT GAGAAACAAC TGTATTCCTA AAAGTAATGG CTCAACTGAT 
TTACAGACAA ATCAGGATAT AGGTACTGCC ATTGTTTCAG ACACTACGGA TGATTTGTGG 
TTTTTAAATG AGACCGTGTC AGAGCAATTA GGTGTTGGAA TAAAAGTTGA AGCTGCTAAT 
TCTGAGCAAA CAAGTGAAGT AGGGAAAACA AGTAACAAGA AGACGGTGGA GGTGGGAAAG 
GATGATGATC TTGAGGACTC CAGGTCCTTG AGCGATGATA CTGACGTGGA ACTTACCTCT 
GAGGATGAGT GGCAGTGTAC GGAATGCAAG AAGTTTAATT CTCCAAGCAA GAGGTACTGT 
TTTCGTTGCT GGGCCTTGAG AAAGGATTGG TATTCGGATT GTTCTAAATT AACTCATTCC 
CTATCTACAT CTAATATTAC TGCCATACCT GAAAAGAAGG ACAATGAAGG AATTGATGTT 
CCCGATTGTA GGAGAACCAT TTCAGCTCCT GTTGTTAGGC CTAAAGATGG ATATTTAAAG 
GAGGAAAAGC CCAGGTTTGA CCCTTGCAAC TCAGTGGGAT TTTTGGATTT GGCTCATAGT 
TCTGAAAGCC AGGAGATCAT CTCAAGCGCG AGAGAACAAA CAGATATTTT TTCTGAGCAG 
AAAGCTGAAA CAGAAAGTAT GGAAGATTTC CAGAATGTCT TGAAGCCGTG TAGCTTATGT 
GAAAAAAGGC CTCGGGATGG GAACATTATT CATGGGAAGA CGAGCCATCT GACGACATGT 
TTCCACTGTG CCAGGAGACT GAAGAAGTCT GGGGCTTCGT GTCCTGCTTG TAAGAAAGAG 
ATTCAGTTGG TTATTAAAGT TTTTATAGCA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289731.1
CDS	84..1556
Translation	MTSHSTSAQCSASDSACRISSEQISQQVRPKLQLLKILHAAGAQGEVFTMKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGDLLGCQSFSVKDPSPLYDMLRKNLVTSASINTDAAQTLALAQDHTMDFPSQDRLKHGATEYSNPRKRTEEEDTHTLPTSRHKCRDSRADEDLIEHLSQDETSRLDLDFEEWDVAGLPWWFLGNLRNNCIPKSNGSTDLQTNQDIGTAIVSDTTDDLWFLNETVSEQLGVGIKVEAANSEQTSEVGKTSNKKTVEVGKDDDLEDSRSLSDDTDVELTSEDEWQCTECKKFNSPSKRYCFRCWALRKDWYSDCSKLTHSLSTSNITAIPEKKDNEGIDVPDCRRTISAPVVRPKDGYLKEEKPRFDPCNSVGFLDLAHSSESQEIISSAREQTDIFSEQKAETESMEDFQNVLKPCSLCEKRPRDGNIIHGKTSHLTTCFHCARRLKKSGASCPACKKEIQLVIKVFIA

Target ORF information:

RefSeq Version	NM_001302802.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302802.1

ORF Insert Sequence:

ATGACATCAC ATTCCACCTC GGCCCAGTGT TCAGCATCTG ACAGTGCTTG CAGAATTTCT 
TCGGAACAAA TTAGTCAGCA GGTGCGGCCA AAACTGCAGC TTTTGAAGAT TTTGCATGCA 
GCAGGTGCGC AGGGGGAAGT ATTCACCATG AAAGAGGTAA TGCACTATCT AGGCCAGTAT 
ATAATGGTGA AGCAGCTCTA TGATCAACAG GAGCAACATA TGGTATACTG TGGTGGAGAT 
CTTTTGGGAG ATCTACTTGG ATGTCAGAGC TTTTCTGTGA AAGATCCAAG CCCTCTCTAT 
GACATGCTAA GAAAGAATCT TGTTACATCA GCTTCTATTA ACACAGATGC TGCTCAGACT 
CTCGCTCTCG CACAGGATCA CACTATGGAT TTTCCAAGTC AAGACCGACT GAAGCACGGT 
GCAACAGAAT ACTCCAATCC CAGAAAAAGA ACTGAAGAAG AGGATACTCA CACACTGCCT 
ACCTCACGAC ATAAATGCAG AGACTCCAGA GCAGATGAAG ACTTGATAGA ACATTTATCT 
CAAGATGAGA CATCTAGGCT TGACCTTGAT TTTGAGGAGT GGGACGTTGC TGGCCTGCCT 
TGGTGGTTTC TAGGGAATTT GAGAAACAAC TGTATTCCTA AAAGTAATGG CTCAACTGAT 
TTACAGACAA ATCAGGATAT AGGTACTGCC ATTGTTTCAG ACACTACGGA TGATTTGTGG 
TTTTTAAATG AGACCGTGTC AGAGCAATTA GGTGTTGGAA TAAAAGTTGA AGCTGCTAAT 
TCTGAGCAAA CAAGTGAAGT AGGGAAAACA AGTAACAAGA AGACGGTGGA GGTGGGAAAG 
GATGATGATC TTGAGGACTC CAGGTCCTTG AGCGATGATA CTGACGTGGA ACTTACCTCT 
GAGGATGAGT GGCAGTGTAC GGAATGCAAG AAGTTTAATT CTCCAAGCAA GAGGTACTGT 
TTTCGTTGCT GGGCCTTGAG AAAGGATTGG TATTCGGATT GTTCTAAATT AACTCATTCC 
CTATCTACAT CTAATATTAC TGCCATACCT GAAAAGAAGG ACAATGAAGG AATTGATGTT 
CCCGATTGTA GGAGAACCAT TTCAGCTCCT GTTGTTAGGC CTAAAGATGG ATATTTAAAG 
GAGGAAAAGC CCAGGTTTGA CCCTTGCAAC TCAGTGGGAT TTTTGGATTT GGCTCATAGT 
TCTGAAAGCC AGGAGATCAT CTCAAGCGCG AGAGAACAAA CAGATATTTT TTCTGAGCAG 
AAAGCTGAAA CAGAAAGTAT GGAAGATTTC CAGAATGTCT TGAAGCCGTG TAGCTTATGT 
GAAAAAAGGC CTCGGGATGG GAACATTATT CATGGGAAGA CGAGCCATCT GACGACATGT 
TTCCACTGTG CCAGGAGACT GAAGAAGTCT GGGGCTTCGT GTCCTGCTTG TAAGAAAGAG 
ATTCAGTTGG TTATTAAAGT TTTTATAGCA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mdm4 ( NM_001302801.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001289730.1 Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 1, mRNA.

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CloneID	OMu27986
Clone ID Related Accession (Same CDS sequence)	XM_006529233.2 , NM_001302802.1 , NM_001302801.1 , XM_006529233.3
Accession Version	NM_001302801.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	protein Mdm4 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CJ101093.1, AK017719.1, AK049576.1, AK083349.1, AK043359.1, AK046448.1 and BC058680.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Both variants 1 and 2 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACATCAC ATTCCACCTC GGCCCAGTGT TCAGCATCTG ACAGTGCTTG CAGAATTTCT 
TCGGAACAAA TTAGTCAGCA GGTGCGGCCA AAACTGCAGC TTTTGAAGAT TTTGCATGCA 
GCAGGTGCGC AGGGGGAAGT ATTCACCATG AAAGAGGTAA TGCACTATCT AGGCCAGTAT 
ATAATGGTGA AGCAGCTCTA TGATCAACAG GAGCAACATA TGGTATACTG TGGTGGAGAT 
CTTTTGGGAG ATCTACTTGG ATGTCAGAGC TTTTCTGTGA AAGATCCAAG CCCTCTCTAT 
GACATGCTAA GAAAGAATCT TGTTACATCA GCTTCTATTA ACACAGATGC TGCTCAGACT 
CTCGCTCTCG CACAGGATCA CACTATGGAT TTTCCAAGTC AAGACCGACT GAAGCACGGT 
GCAACAGAAT ACTCCAATCC CAGAAAAAGA ACTGAAGAAG AGGATACTCA CACACTGCCT 
ACCTCACGAC ATAAATGCAG AGACTCCAGA GCAGATGAAG ACTTGATAGA ACATTTATCT 
CAAGATGAGA CATCTAGGCT TGACCTTGAT TTTGAGGAGT GGGACGTTGC TGGCCTGCCT 
TGGTGGTTTC TAGGGAATTT GAGAAACAAC TGTATTCCTA AAAGTAATGG CTCAACTGAT 
TTACAGACAA ATCAGGATAT AGGTACTGCC ATTGTTTCAG ACACTACGGA TGATTTGTGG 
TTTTTAAATG AGACCGTGTC AGAGCAATTA GGTGTTGGAA TAAAAGTTGA AGCTGCTAAT 
TCTGAGCAAA CAAGTGAAGT AGGGAAAACA AGTAACAAGA AGACGGTGGA GGTGGGAAAG 
GATGATGATC TTGAGGACTC CAGGTCCTTG AGCGATGATA CTGACGTGGA ACTTACCTCT 
GAGGATGAGT GGCAGTGTAC GGAATGCAAG AAGTTTAATT CTCCAAGCAA GAGGTACTGT 
TTTCGTTGCT GGGCCTTGAG AAAGGATTGG TATTCGGATT GTTCTAAATT AACTCATTCC 
CTATCTACAT CTAATATTAC TGCCATACCT GAAAAGAAGG ACAATGAAGG AATTGATGTT 
CCCGATTGTA GGAGAACCAT TTCAGCTCCT GTTGTTAGGC CTAAAGATGG ATATTTAAAG 
GAGGAAAAGC CCAGGTTTGA CCCTTGCAAC TCAGTGGGAT TTTTGGATTT GGCTCATAGT 
TCTGAAAGCC AGGAGATCAT CTCAAGCGCG AGAGAACAAA CAGATATTTT TTCTGAGCAG 
AAAGCTGAAA CAGAAAGTAT GGAAGATTTC CAGAATGTCT TGAAGCCGTG TAGCTTATGT 
GAAAAAAGGC CTCGGGATGG GAACATTATT CATGGGAAGA CGAGCCATCT GACGACATGT 
TTCCACTGTG CCAGGAGACT GAAGAAGTCT GGGGCTTCGT GTCCTGCTTG TAAGAAAGAG 
ATTCAGTTGG TTATTAAAGT TTTTATAGCA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289730.1
CDS	200..1672
Translation	MTSHSTSAQCSASDSACRISSEQISQQVRPKLQLLKILHAAGAQGEVFTMKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGDLLGCQSFSVKDPSPLYDMLRKNLVTSASINTDAAQTLALAQDHTMDFPSQDRLKHGATEYSNPRKRTEEEDTHTLPTSRHKCRDSRADEDLIEHLSQDETSRLDLDFEEWDVAGLPWWFLGNLRNNCIPKSNGSTDLQTNQDIGTAIVSDTTDDLWFLNETVSEQLGVGIKVEAANSEQTSEVGKTSNKKTVEVGKDDDLEDSRSLSDDTDVELTSEDEWQCTECKKFNSPSKRYCFRCWALRKDWYSDCSKLTHSLSTSNITAIPEKKDNEGIDVPDCRRTISAPVVRPKDGYLKEEKPRFDPCNSVGFLDLAHSSESQEIISSAREQTDIFSEQKAETESMEDFQNVLKPCSLCEKRPRDGNIIHGKTSHLTTCFHCARRLKKSGASCPACKKEIQLVIKVFIA

Target ORF information:

RefSeq Version	NM_001302801.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302801.1

ORF Insert Sequence:

ATGACATCAC ATTCCACCTC GGCCCAGTGT TCAGCATCTG ACAGTGCTTG CAGAATTTCT 
TCGGAACAAA TTAGTCAGCA GGTGCGGCCA AAACTGCAGC TTTTGAAGAT TTTGCATGCA 
GCAGGTGCGC AGGGGGAAGT ATTCACCATG AAAGAGGTAA TGCACTATCT AGGCCAGTAT 
ATAATGGTGA AGCAGCTCTA TGATCAACAG GAGCAACATA TGGTATACTG TGGTGGAGAT 
CTTTTGGGAG ATCTACTTGG ATGTCAGAGC TTTTCTGTGA AAGATCCAAG CCCTCTCTAT 
GACATGCTAA GAAAGAATCT TGTTACATCA GCTTCTATTA ACACAGATGC TGCTCAGACT 
CTCGCTCTCG CACAGGATCA CACTATGGAT TTTCCAAGTC AAGACCGACT GAAGCACGGT 
GCAACAGAAT ACTCCAATCC CAGAAAAAGA ACTGAAGAAG AGGATACTCA CACACTGCCT 
ACCTCACGAC ATAAATGCAG AGACTCCAGA GCAGATGAAG ACTTGATAGA ACATTTATCT 
CAAGATGAGA CATCTAGGCT TGACCTTGAT TTTGAGGAGT GGGACGTTGC TGGCCTGCCT 
TGGTGGTTTC TAGGGAATTT GAGAAACAAC TGTATTCCTA AAAGTAATGG CTCAACTGAT 
TTACAGACAA ATCAGGATAT AGGTACTGCC ATTGTTTCAG ACACTACGGA TGATTTGTGG 
TTTTTAAATG AGACCGTGTC AGAGCAATTA GGTGTTGGAA TAAAAGTTGA AGCTGCTAAT 
TCTGAGCAAA CAAGTGAAGT AGGGAAAACA AGTAACAAGA AGACGGTGGA GGTGGGAAAG 
GATGATGATC TTGAGGACTC CAGGTCCTTG AGCGATGATA CTGACGTGGA ACTTACCTCT 
GAGGATGAGT GGCAGTGTAC GGAATGCAAG AAGTTTAATT CTCCAAGCAA GAGGTACTGT 
TTTCGTTGCT GGGCCTTGAG AAAGGATTGG TATTCGGATT GTTCTAAATT AACTCATTCC 
CTATCTACAT CTAATATTAC TGCCATACCT GAAAAGAAGG ACAATGAAGG AATTGATGTT 
CCCGATTGTA GGAGAACCAT TTCAGCTCCT GTTGTTAGGC CTAAAGATGG ATATTTAAAG 
GAGGAAAAGC CCAGGTTTGA CCCTTGCAAC TCAGTGGGAT TTTTGGATTT GGCTCATAGT 
TCTGAAAGCC AGGAGATCAT CTCAAGCGCG AGAGAACAAA CAGATATTTT TTCTGAGCAG 
AAAGCTGAAA CAGAAAGTAT GGAAGATTTC CAGAATGTCT TGAAGCCGTG TAGCTTATGT 
GAAAAAAGGC CTCGGGATGG GAACATTATT CATGGGAAGA CGAGCCATCT GACGACATGT 
TTCCACTGTG CCAGGAGACT GAAGAAGTCT GGGGCTTCGT GTCCTGCTTG TAAGAAAGAG 
ATTCAGTTGG TTATTAAAGT TTTTATAGCA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mdm4 ( NM_001302804.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001289733.1 Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 5, mRNA.

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CloneID	OMu68193
Clone ID Related Accession (Same CDS sequence)	NM_001302804.1
Accession Version	NM_001302804.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	protein Mdm4 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CJ101093.1, AK049576.1, AK083349.1, AK043359.1, AK046448.1 and BC058680.1. Transcript Variant: This variant (5) uses an alternate splice site in an internal exon, compared to variant 1. This variant represents translation initiation at a downstream AUG compared to variant 1; the 5'-most initiation codon, as used in variant 1, is associated with a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning may allow translation initiation at the downstream AUG to encode an isoform (3) that has a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATTTTC CAAGTCAAGA CCGACTGAAG CACGGTGCAA CAGAATACTC CAATCCCAGA 
AAAAGAACTG AAGAAGAGGA TACTCACACA CTGCCTACCT CACGACATAA ATGCAGAGAC 
TCCAGAGCAG ATGAAGACTT GATAGAACAT TTATCTCAAG ATGAGACATC TAGGCTTGAC 
CTTGATTTTG AGGAGTGGGA CGTTGCTGGC CTGCCTTGGT GGTTTCTAGG GAATTTGAGA 
AACAACTGTA TTCCTAAAAG TAATGGCTCA ACTGATTTAC AGACAAATCA GGATATAGGT 
ACTGCCATTG TTTCAGACAC TACGGATGAT TTGTGGTTTT TAAATGAGAC CGTGTCAGAG 
CAATTAGGTG TTGGAATAAA AGTTGAAGCT GCTAATTCTG AGCAAACAAG TGAAGTAGGG 
AAAACAAGTA ACAAGAAGAC GGTGGAGGTG GGAAAGGATG ATGATCTTGA GGACTCCAGG 
TCCTTGAGCG ATGATACTGA CGTGGAACTT ACCTCTGAGG ATGAGTGGCA GTGTACGGAA 
TGCAAGAAGT TTAATTCTCC AAGCAAGAGG TACTGTTTTC GTTGCTGGGC CTTGAGAAAG 
GATTGGTATT CGGATTGTTC TAAATTAACT CATTCCCTAT CTACATCTAA TATTACTGCC 
ATACCTGAAA AGAAGGACAA TGAAGGAATT GATGTTCCCG ATTGTAGGAG AACCATTTCA 
GCTCCTGTTG TTAGGCCTAA AGATGGATAT TTAAAGGAGG AAAAGCCCAG GTTTGACCCT 
TGCAACTCAG TGGGATTTTT GGATTTGGCT CATAGTTCTG AAAGCCAGGA GATCATCTCA 
AGCGCGAGAG AACAAACAGA TATTTTTTCT GAGCAGAAAG CTGAAACAGA AAGTATGGAA 
GATTTCCAGA ATGTCTTGAA GCCGTGTAGC TTATGTGAAA AAAGGCCTCG GGATGGGAAC 
ATTATTCATG GGAAGACGAG CCATCTGACG ACATGTTTCC ACTGTGCCAG GAGACTGAAG 
AAGTCTGGGG CTTCGTGTCC TGCTTGTAAG AAAGAGATTC AGTTGGTTAT TAAAGTTTTT 
ATAGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289733.1
CDS	555..1643
Translation	MDFPSQDRLKHGATEYSNPRKRTEEEDTHTLPTSRHKCRDSRADEDLIEHLSQDETSRLDLDFEEWDVAGLPWWFLGNLRNNCIPKSNGSTDLQTNQDIGTAIVSDTTDDLWFLNETVSEQLGVGIKVEAANSEQTSEVGKTSNKKTVEVGKDDDLEDSRSLSDDTDVELTSEDEWQCTECKKFNSPSKRYCFRCWALRKDWYSDCSKLTHSLSTSNITAIPEKKDNEGIDVPDCRRTISAPVVRPKDGYLKEEKPRFDPCNSVGFLDLAHSSESQEIISSAREQTDIFSEQKAETESMEDFQNVLKPCSLCEKRPRDGNIIHGKTSHLTTCFHCARRLKKSGASCPACKKEIQLVIKVFIA

Target ORF information:

RefSeq Version	NM_001302804.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302804.1

ORF Insert Sequence:

ATGGATTTTC CAAGTCAAGA CCGACTGAAG CACGGTGCAA CAGAATACTC CAATCCCAGA 
AAAAGAACTG AAGAAGAGGA TACTCACACA CTGCCTACCT CACGACATAA ATGCAGAGAC 
TCCAGAGCAG ATGAAGACTT GATAGAACAT TTATCTCAAG ATGAGACATC TAGGCTTGAC 
CTTGATTTTG AGGAGTGGGA CGTTGCTGGC CTGCCTTGGT GGTTTCTAGG GAATTTGAGA 
AACAACTGTA TTCCTAAAAG TAATGGCTCA ACTGATTTAC AGACAAATCA GGATATAGGT 
ACTGCCATTG TTTCAGACAC TACGGATGAT TTGTGGTTTT TAAATGAGAC CGTGTCAGAG 
CAATTAGGTG TTGGAATAAA AGTTGAAGCT GCTAATTCTG AGCAAACAAG TGAAGTAGGG 
AAAACAAGTA ACAAGAAGAC GGTGGAGGTG GGAAAGGATG ATGATCTTGA GGACTCCAGG 
TCCTTGAGCG ATGATACTGA CGTGGAACTT ACCTCTGAGG ATGAGTGGCA GTGTACGGAA 
TGCAAGAAGT TTAATTCTCC AAGCAAGAGG TACTGTTTTC GTTGCTGGGC CTTGAGAAAG 
GATTGGTATT CGGATTGTTC TAAATTAACT CATTCCCTAT CTACATCTAA TATTACTGCC 
ATACCTGAAA AGAAGGACAA TGAAGGAATT GATGTTCCCG ATTGTAGGAG AACCATTTCA 
GCTCCTGTTG TTAGGCCTAA AGATGGATAT TTAAAGGAGG AAAAGCCCAG GTTTGACCCT 
TGCAACTCAG TGGGATTTTT GGATTTGGCT CATAGTTCTG AAAGCCAGGA GATCATCTCA 
AGCGCGAGAG AACAAACAGA TATTTTTTCT GAGCAGAAAG CTGAAACAGA AAGTATGGAA 
GATTTCCAGA ATGTCTTGAA GCCGTGTAGC TTATGTGAAA AAAGGCCTCG GGATGGGAAC 
ATTATTCATG GGAAGACGAG CCATCTGACG ACATGTTTCC ACTGTGCCAG GAGACTGAAG 
AAGTCTGGGG CTTCGTGTCC TGCTTGTAAG AAAGAGATTC AGTTGGTTAT TAAAGTTTTT 
ATAGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mdm4 ( XM_006529233.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529296.1 Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant X1, mRNA.

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CloneID	OMu27986
Clone ID Related Accession (Same CDS sequence)	XM_006529233.2 , NM_001302802.1 , NM_001302801.1 , XM_006529233.3
Accession Version	XM_006529233.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	protein Mdm4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006529233.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACATCAC ATTCCACCTC GGCCCAGTGT TCAGCATCTG ACAGTGCTTG CAGAATTTCT 
TCGGAACAAA TTAGTCAGCA GGTGCGGCCA AAACTGCAGC TTTTGAAGAT TTTGCATGCA 
GCAGGTGCGC AGGGGGAAGT ATTCACCATG AAAGAGGTAA TGCACTATCT AGGCCAGTAT 
ATAATGGTGA AGCAGCTCTA TGATCAACAG GAGCAACATA TGGTATACTG TGGTGGAGAT 
CTTTTGGGAG ATCTACTTGG ATGTCAGAGC TTTTCTGTGA AAGATCCAAG CCCTCTCTAT 
GACATGCTAA GAAAGAATCT TGTTACATCA GCTTCTATTA ACACAGATGC TGCTCAGACT 
CTCGCTCTCG CACAGGATCA CACTATGGAT TTTCCAAGTC AAGACCGACT GAAGCACGGT 
GCAACAGAAT ACTCCAATCC CAGAAAAAGA ACTGAAGAAG AGGATACTCA CACACTGCCT 
ACCTCACGAC ATAAATGCAG AGACTCCAGA GCAGATGAAG ACTTGATAGA ACATTTATCT 
CAAGATGAGA CATCTAGGCT TGACCTTGAT TTTGAGGAGT GGGACGTTGC TGGCCTGCCT 
TGGTGGTTTC TAGGGAATTT GAGAAACAAC TGTATTCCTA AAAGTAATGG CTCAACTGAT 
TTACAGACAA ATCAGGATAT AGGTACTGCC ATTGTTTCAG ACACTACGGA TGATTTGTGG 
TTTTTAAATG AGACCGTGTC AGAGCAATTA GGTGTTGGAA TAAAAGTTGA AGCTGCTAAT 
TCTGAGCAAA CAAGTGAAGT AGGGAAAACA AGTAACAAGA AGACGGTGGA GGTGGGAAAG 
GATGATGATC TTGAGGACTC CAGGTCCTTG AGCGATGATA CTGACGTGGA ACTTACCTCT 
GAGGATGAGT GGCAGTGTAC GGAATGCAAG AAGTTTAATT CTCCAAGCAA GAGGTACTGT 
TTTCGTTGCT GGGCCTTGAG AAAGGATTGG TATTCGGATT GTTCTAAATT AACTCATTCC 
CTATCTACAT CTAATATTAC TGCCATACCT GAAAAGAAGG ACAATGAAGG AATTGATGTT 
CCCGATTGTA GGAGAACCAT TTCAGCTCCT GTTGTTAGGC CTAAAGATGG ATATTTAAAG 
GAGGAAAAGC CCAGGTTTGA CCCTTGCAAC TCAGTGGGAT TTTTGGATTT GGCTCATAGT 
TCTGAAAGCC AGGAGATCAT CTCAAGCGCG AGAGAACAAA CAGATATTTT TTCTGAGCAG 
AAAGCTGAAA CAGAAAGTAT GGAAGATTTC CAGAATGTCT TGAAGCCGTG TAGCTTATGT 
GAAAAAAGGC CTCGGGATGG GAACATTATT CATGGGAAGA CGAGCCATCT GACGACATGT 
TTCCACTGTG CCAGGAGACT GAAGAAGTCT GGGGCTTCGT GTCCTGCTTG TAAGAAAGAG 
ATTCAGTTGG TTATTAAAGT TTTTATAGCA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529296.1
CDS	256..1728
Translation	MTSHSTSAQCSASDSACRISSEQISQQVRPKLQLLKILHAAGAQGEVFTMKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGDLLGCQSFSVKDPSPLYDMLRKNLVTSASINTDAAQTLALAQDHTMDFPSQDRLKHGATEYSNPRKRTEEEDTHTLPTSRHKCRDSRADEDLIEHLSQDETSRLDLDFEEWDVAGLPWWFLGNLRNNCIPKSNGSTDLQTNQDIGTAIVSDTTDDLWFLNETVSEQLGVGIKVEAANSEQTSEVGKTSNKKTVEVGKDDDLEDSRSLSDDTDVELTSEDEWQCTECKKFNSPSKRYCFRCWALRKDWYSDCSKLTHSLSTSNITAIPEKKDNEGIDVPDCRRTISAPVVRPKDGYLKEEKPRFDPCNSVGFLDLAHSSESQEIISSAREQTDIFSEQKAETESMEDFQNVLKPCSLCEKRPRDGNIIHGKTSHLTTCFHCARRLKKSGASCPACKKEIQLVIKVFIA

Target ORF information:

RefSeq Version	XM_006529233.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529233.2

ORF Insert Sequence:

ATGACATCAC ATTCCACCTC GGCCCAGTGT TCAGCATCTG ACAGTGCTTG CAGAATTTCT 
TCGGAACAAA TTAGTCAGCA GGTGCGGCCA AAACTGCAGC TTTTGAAGAT TTTGCATGCA 
GCAGGTGCGC AGGGGGAAGT ATTCACCATG AAAGAGGTAA TGCACTATCT AGGCCAGTAT 
ATAATGGTGA AGCAGCTCTA TGATCAACAG GAGCAACATA TGGTATACTG TGGTGGAGAT 
CTTTTGGGAG ATCTACTTGG ATGTCAGAGC TTTTCTGTGA AAGATCCAAG CCCTCTCTAT 
GACATGCTAA GAAAGAATCT TGTTACATCA GCTTCTATTA ACACAGATGC TGCTCAGACT 
CTCGCTCTCG CACAGGATCA CACTATGGAT TTTCCAAGTC AAGACCGACT GAAGCACGGT 
GCAACAGAAT ACTCCAATCC CAGAAAAAGA ACTGAAGAAG AGGATACTCA CACACTGCCT 
ACCTCACGAC ATAAATGCAG AGACTCCAGA GCAGATGAAG ACTTGATAGA ACATTTATCT 
CAAGATGAGA CATCTAGGCT TGACCTTGAT TTTGAGGAGT GGGACGTTGC TGGCCTGCCT 
TGGTGGTTTC TAGGGAATTT GAGAAACAAC TGTATTCCTA AAAGTAATGG CTCAACTGAT 
TTACAGACAA ATCAGGATAT AGGTACTGCC ATTGTTTCAG ACACTACGGA TGATTTGTGG 
TTTTTAAATG AGACCGTGTC AGAGCAATTA GGTGTTGGAA TAAAAGTTGA AGCTGCTAAT 
TCTGAGCAAA CAAGTGAAGT AGGGAAAACA AGTAACAAGA AGACGGTGGA GGTGGGAAAG 
GATGATGATC TTGAGGACTC CAGGTCCTTG AGCGATGATA CTGACGTGGA ACTTACCTCT 
GAGGATGAGT GGCAGTGTAC GGAATGCAAG AAGTTTAATT CTCCAAGCAA GAGGTACTGT 
TTTCGTTGCT GGGCCTTGAG AAAGGATTGG TATTCGGATT GTTCTAAATT AACTCATTCC 
CTATCTACAT CTAATATTAC TGCCATACCT GAAAAGAAGG ACAATGAAGG AATTGATGTT 
CCCGATTGTA GGAGAACCAT TTCAGCTCCT GTTGTTAGGC CTAAAGATGG ATATTTAAAG 
GAGGAAAAGC CCAGGTTTGA CCCTTGCAAC TCAGTGGGAT TTTTGGATTT GGCTCATAGT 
TCTGAAAGCC AGGAGATCAT CTCAAGCGCG AGAGAACAAA CAGATATTTT TTCTGAGCAG 
AAAGCTGAAA CAGAAAGTAT GGAAGATTTC CAGAATGTCT TGAAGCCGTG TAGCTTATGT 
GAAAAAAGGC CTCGGGATGG GAACATTATT CATGGGAAGA CGAGCCATCT GACGACATGT 
TTCCACTGTG CCAGGAGACT GAAGAAGTCT GGGGCTTCGT GTCCTGCTTG TAAGAAAGAG 
ATTCAGTTGG TTATTAAAGT TTTTATAGCA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mdm4 ( XM_006529233.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529296.1 Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant X1, mRNA.

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CloneID	OMu27986
Clone ID Related Accession (Same CDS sequence)	XM_006529233.2 , NM_001302802.1 , NM_001302801.1 , XM_006529233.3
Accession Version	XM_006529233.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	protein Mdm4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006529233.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACATCAC ATTCCACCTC GGCCCAGTGT TCAGCATCTG ACAGTGCTTG CAGAATTTCT 
TCGGAACAAA TTAGTCAGCA GGTGCGGCCA AAACTGCAGC TTTTGAAGAT TTTGCATGCA 
GCAGGTGCGC AGGGGGAAGT ATTCACCATG AAAGAGGTAA TGCACTATCT AGGCCAGTAT 
ATAATGGTGA AGCAGCTCTA TGATCAACAG GAGCAACATA TGGTATACTG TGGTGGAGAT 
CTTTTGGGAG ATCTACTTGG ATGTCAGAGC TTTTCTGTGA AAGATCCAAG CCCTCTCTAT 
GACATGCTAA GAAAGAATCT TGTTACATCA GCTTCTATTA ACACAGATGC TGCTCAGACT 
CTCGCTCTCG CACAGGATCA CACTATGGAT TTTCCAAGTC AAGACCGACT GAAGCACGGT 
GCAACAGAAT ACTCCAATCC CAGAAAAAGA ACTGAAGAAG AGGATACTCA CACACTGCCT 
ACCTCACGAC ATAAATGCAG AGACTCCAGA GCAGATGAAG ACTTGATAGA ACATTTATCT 
CAAGATGAGA CATCTAGGCT TGACCTTGAT TTTGAGGAGT GGGACGTTGC TGGCCTGCCT 
TGGTGGTTTC TAGGGAATTT GAGAAACAAC TGTATTCCTA AAAGTAATGG CTCAACTGAT 
TTACAGACAA ATCAGGATAT AGGTACTGCC ATTGTTTCAG ACACTACGGA TGATTTGTGG 
TTTTTAAATG AGACCGTGTC AGAGCAATTA GGTGTTGGAA TAAAAGTTGA AGCTGCTAAT 
TCTGAGCAAA CAAGTGAAGT AGGGAAAACA AGTAACAAGA AGACGGTGGA GGTGGGAAAG 
GATGATGATC TTGAGGACTC CAGGTCCTTG AGCGATGATA CTGACGTGGA ACTTACCTCT 
GAGGATGAGT GGCAGTGTAC GGAATGCAAG AAGTTTAATT CTCCAAGCAA GAGGTACTGT 
TTTCGTTGCT GGGCCTTGAG AAAGGATTGG TATTCGGATT GTTCTAAATT AACTCATTCC 
CTATCTACAT CTAATATTAC TGCCATACCT GAAAAGAAGG ACAATGAAGG AATTGATGTT 
CCCGATTGTA GGAGAACCAT TTCAGCTCCT GTTGTTAGGC CTAAAGATGG ATATTTAAAG 
GAGGAAAAGC CCAGGTTTGA CCCTTGCAAC TCAGTGGGAT TTTTGGATTT GGCTCATAGT 
TCTGAAAGCC AGGAGATCAT CTCAAGCGCG AGAGAACAAA CAGATATTTT TTCTGAGCAG 
AAAGCTGAAA CAGAAAGTAT GGAAGATTTC CAGAATGTCT TGAAGCCGTG TAGCTTATGT 
GAAAAAAGGC CTCGGGATGG GAACATTATT CATGGGAAGA CGAGCCATCT GACGACATGT 
TTCCACTGTG CCAGGAGACT GAAGAAGTCT GGGGCTTCGT GTCCTGCTTG TAAGAAAGAG 
ATTCAGTTGG TTATTAAAGT TTTTATAGCA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529296.1
CDS	251..1723
Translation	MTSHSTSAQCSASDSACRISSEQISQQVRPKLQLLKILHAAGAQGEVFTMKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGDLLGCQSFSVKDPSPLYDMLRKNLVTSASINTDAAQTLALAQDHTMDFPSQDRLKHGATEYSNPRKRTEEEDTHTLPTSRHKCRDSRADEDLIEHLSQDETSRLDLDFEEWDVAGLPWWFLGNLRNNCIPKSNGSTDLQTNQDIGTAIVSDTTDDLWFLNETVSEQLGVGIKVEAANSEQTSEVGKTSNKKTVEVGKDDDLEDSRSLSDDTDVELTSEDEWQCTECKKFNSPSKRYCFRCWALRKDWYSDCSKLTHSLSTSNITAIPEKKDNEGIDVPDCRRTISAPVVRPKDGYLKEEKPRFDPCNSVGFLDLAHSSESQEIISSAREQTDIFSEQKAETESMEDFQNVLKPCSLCEKRPRDGNIIHGKTSHLTTCFHCARRLKKSGASCPACKKEIQLVIKVFIA

Target ORF information:

RefSeq Version	XM_006529233.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus transformed mouse 3T3 cell double minute 4 (Mdm4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529233.3

ORF Insert Sequence:

ATGACATCAC ATTCCACCTC GGCCCAGTGT TCAGCATCTG ACAGTGCTTG CAGAATTTCT 
TCGGAACAAA TTAGTCAGCA GGTGCGGCCA AAACTGCAGC TTTTGAAGAT TTTGCATGCA 
GCAGGTGCGC AGGGGGAAGT ATTCACCATG AAAGAGGTAA TGCACTATCT AGGCCAGTAT 
ATAATGGTGA AGCAGCTCTA TGATCAACAG GAGCAACATA TGGTATACTG TGGTGGAGAT 
CTTTTGGGAG ATCTACTTGG ATGTCAGAGC TTTTCTGTGA AAGATCCAAG CCCTCTCTAT 
GACATGCTAA GAAAGAATCT TGTTACATCA GCTTCTATTA ACACAGATGC TGCTCAGACT 
CTCGCTCTCG CACAGGATCA CACTATGGAT TTTCCAAGTC AAGACCGACT GAAGCACGGT 
GCAACAGAAT ACTCCAATCC CAGAAAAAGA ACTGAAGAAG AGGATACTCA CACACTGCCT 
ACCTCACGAC ATAAATGCAG AGACTCCAGA GCAGATGAAG ACTTGATAGA ACATTTATCT 
CAAGATGAGA CATCTAGGCT TGACCTTGAT TTTGAGGAGT GGGACGTTGC TGGCCTGCCT 
TGGTGGTTTC TAGGGAATTT GAGAAACAAC TGTATTCCTA AAAGTAATGG CTCAACTGAT 
TTACAGACAA ATCAGGATAT AGGTACTGCC ATTGTTTCAG ACACTACGGA TGATTTGTGG 
TTTTTAAATG AGACCGTGTC AGAGCAATTA GGTGTTGGAA TAAAAGTTGA AGCTGCTAAT 
TCTGAGCAAA CAAGTGAAGT AGGGAAAACA AGTAACAAGA AGACGGTGGA GGTGGGAAAG 
GATGATGATC TTGAGGACTC CAGGTCCTTG AGCGATGATA CTGACGTGGA ACTTACCTCT 
GAGGATGAGT GGCAGTGTAC GGAATGCAAG AAGTTTAATT CTCCAAGCAA GAGGTACTGT 
TTTCGTTGCT GGGCCTTGAG AAAGGATTGG TATTCGGATT GTTCTAAATT AACTCATTCC 
CTATCTACAT CTAATATTAC TGCCATACCT GAAAAGAAGG ACAATGAAGG AATTGATGTT 
CCCGATTGTA GGAGAACCAT TTCAGCTCCT GTTGTTAGGC CTAAAGATGG ATATTTAAAG 
GAGGAAAAGC CCAGGTTTGA CCCTTGCAAC TCAGTGGGAT TTTTGGATTT GGCTCATAGT 
TCTGAAAGCC AGGAGATCAT CTCAAGCGCG AGAGAACAAA CAGATATTTT TTCTGAGCAG 
AAAGCTGAAA CAGAAAGTAT GGAAGATTTC CAGAATGTCT TGAAGCCGTG TAGCTTATGT 
GAAAAAAGGC CTCGGGATGG GAACATTATT CATGGGAAGA CGAGCCATCT GACGACATGT 
TTCCACTGTG CCAGGAGACT GAAGAAGTCT GGGGCTTCGT GTCCTGCTTG TAAGAAAGAG 
ATTCAGTTGG TTATTAAAGT TTTTATAGCA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery.
Genes & development27(17)1903-16(2013 Sep)
Bezzi M,Teo SX,Muller J,Mok WC,Sahu SK,Vardy LA,Bonday ZQ,Guccione E

MDM2, MDMX and p53 in oncogenesis and cancer therapy.
Nature reviews. Cancer13(2)83-96(2013 Feb)
Wade M,Li YC,Wahl GM

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Mdm4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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