gRNAs
The following Mcm3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mcm3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu15727 | |
| Clone ID Related Accession (Same CDS sequence) | NM_008563.3 , NM_008563.2 | |
| Accession Version | NM_008563.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2439bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-30 | |
| Organism | Mus musculus(house mouse) | |
| Product | DNA replication licensing factor MCM3 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC156980.9 and AC159614.7. On Feb 14, 2018 this sequence version replaced NM_008563.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK145563.1, AK133850.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164140 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGCGGGCA CAGTAGTGCT GGATGATGTG GAGCTGCGGG AAGCGCAGAG AGACTACTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_032589.1 |
| CDS | 105..2543 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_008563.3 |
1 | ATGGCGGGCA CAGTAGTGCT GGATGATGTG GAGCTGCGGG AAGCGCAGAG AGACTACTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu15727 | |
| Clone ID Related Accession (Same CDS sequence) | NM_008563.3 , NM_008563.2 | |
| Accession Version | NM_008563.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2439bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-12-27 | |
| Organism | Mus musculus(house mouse) | |
| Product | DNA replication licensing factor MCM3 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC156980.9 and AC159614.7. On Nov 17, 2006 this sequence version replaced NM_008563.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC031700.1, AK133850.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164140 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCGGGCA CAGTAGTGCT GGATGATGTG GAGCTGCGGG AAGCGCAGAG AGACTACTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_032589.1 |
| CDS | 6..2444 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_008563.2 |
1 | ATGGCGGGCA CAGTAGTGCT GGATGATGTG GAGCTGCGGG AAGCGCAGAG AGACTACTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu85049 | |
| Clone ID Related Accession (Same CDS sequence) | XM_030251926.1 | |
| Accession Version | XM_030251926.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2301bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | DNA replication licensing factor MCM3 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTGGAGCT GCGGGAAGCG CAGAGAGACT ACTTGGACTT CCTGGATGAC GAGCCTCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_030107786.1 |
| CDS | 1..2301 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_030251926.1 |
1 | ATGTGGAGCT GCGGGAAGCG CAGAGAGACT ACTTGGACTT CCTGGATGAC GAGCCTCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The pathological consequences of impaired genome integrity in humans; disorders of the DNA replication machinery. |
Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality. |
