Mbd2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mbd2
Entrez Gene ID	17191
Full Name	methyl-CpG binding domain protein 2
Synonyms	MBD2a
General protein information	Preferred Names methyl-CpG binding domain protein 2 Names methyl-CpG-binding domain protein 2 methyl-CpG-binding protein MBD2 testis-specific methyl-CpG binding protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18 E2\|18 44.54 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001311071.1	NP_001298000.1	methyl-CpG-binding domain protein 2 isoform 2
NM_010773.2	NP_034903.2	methyl-CpG-binding domain protein 2 isoform 1
XM_006525711.3	XP_006525774.1	methyl-CpG-binding domain protein 2 isoform X2
XM_006525710.3	XP_006525773.1	methyl-CpG-binding domain protein 2 isoform X1
XM_006525711.4	XP_006525774.1	methyl-CpG-binding domain protein 2 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MBD2	XP_512139.4
Danio rerio (zebrafish)	mbd2	NP_997933.1
Homo sapiens (human)	MBD2	NP_003918.1
Bos taurus (cattle)	MBD2	XP_002697814.1
Rattus norvegicus (Norway rat)	Mbd2	NP_001108497.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003982	XP_003436675.1
	MBD2	XP_001082249.1
Mus musculus (house mouse)	Mbd2	NP_034903.2
Gallus gallus (chicken)	MBD2	NP_001012403.1
Canis lupus familiaris (dog)	MBD2	XP_005615735.1
Drosophila melanogaster (fruit fly)	MBD-like	NP_731370.1

Gene Ontology
Bibliography

Related articles in PubMed

MBD2 ablation impairs lymphopoiesis and impedes progression and maintenance of T-ALL.
Zhou M, Zhou K, Cheng L, Chen X, Wang J, Wang XM, Zhang Y, Yu Q, Zhang S, Wang D, Huang L, Huang M, Ma D, Cheng T, Wang CY, Yuan W, Zhou J
Cancer research(2018 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MBD2 has a critical role in 'rewriting' the cancer methylome at specific regulatory regions.
Title: Methyl-CpG-binding protein MBD2 plays a key role in maintenance and spread of DNA methylation at CpG islands and shores in cancer.

Loss of Mbd2 resulted in impaired implementation of above DNA methylation changes associated with altered energy homeostasis, which then protected mice from HFD-induced obesity and insulin resistance.
Title: Loss of Mbd2 Protects Mice Against High-Fat Diet-Induced Obesity and Insulin Resistance by Regulating the Homeostasis of Energy Storage and Expenditure.

It has been shown that chromatin localization of Mbd2 and Mbd3 is highly overlapping, and both proteins are interdependent for chromatin association.
Title: DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells.

Mbd2 has a key role regulating expression of a range of genes that are associated with optimal dendritic cell activation and function.
Title: A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells.

MBD2 targets short interspersed nuclear elements, but does not exclude RNA Polymerase III.
Title: SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation.

The following Mbd2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mbd2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu54428	XM_006525711.4 Latest version!	Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu18158	NM_010773.2 Latest version!	Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OMu68185	NM_001311071.1 Latest version!	Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
OMu54427	XM_006525710.3 Latest version!	Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OMu54428	XM_006525711.3	Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mbd2 ( XM_006525711.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006525774.1 Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu54428
Clone ID Related Accession (Same CDS sequence)	XM_006525711.3 , XM_006525711.4
Accession Version	XM_006525711.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	methyl-CpG-binding domain protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006525711.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGCGCGC ACCCGGGGGG AGGCCGCTGC TGCCCGGAGC AGGAGGAGGG GGAGAGCGCG 
GCGGGCGGCA GCGGCGCTGG CGGCGACTCC GCCATAGAGC AGGGGGGCCA GGGCAGCGCG 
CTCGCTCCGT CCCCGGTGAG CGGCGTGCGC AGGGAAGGCG CTCGGGGCGG CGGCCGTGGC 
CGGGGGCGGT GGAAGCAGGC GGCCCGGGGC GGCGGCGTCT GTGGCCGTGG CCGTGGCCGT 
GGCCGGGGTC GGGGCCGTGG CCGGGGCCGG GGCCGGGGCC GCGGCCGTCC CCAGAGTGGC 
GGCAGCGGCC TTGGCGGCGA CGGCGGCGGC GGCGCGGGCG GCTGCGGCGG CGGCAGCGGT 
GGCGGCGTCG CCCCCCGGCG GGATCCTGTC CCTTTCCCGT CGGGGAGCTC GGGGCCGGGG 
CCCAGGGGAC CCCGGGCCAC GGAGAGCGGG AAGAGGATGG ACTGCCCGGC CCTCCCCCCC 
GGATGGAAGA AGGAGGAAGT GATCCGAAAA TCAGGGCTCA GTGCTGGCAA GAGCGATGTC 
TACTACTTCA GTCCAAGTGG TAAGAAGTTC AGAAGTAAAC CTCAGCTGGC AAGATACCTG 
GGAAATGCTG TTGACCTTAG CAGTTTTGAC TTCAGGACCG GCAAGATGAT GCCTAGTAAA 
TTACAGAAGA ACAAGCAGAG ACTCCGGAAT GACCCCCTCA ATCAGAACAA GCCGCTCTGG 
ACCACTTGCT CGCTCCCTCG CTCGCGCTTC ACCCGCAACA TGGCATGCGC TCTCCGGATC 
TGCTTGCTTC TGTGCTGTCT CCTGTGCTTG GAATGTGCTC CCCCCCACCC TCACCCCCTG 
ACCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006525774.1
CDS	193..1041
Translation	MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAARGGGVCGRGRGRGRGRGRGRGRGRGRGRPQSGGSGLGGDGGGGAGGCGGGSGGGVAPRRDPVPFPSGSSGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNAVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKPLWTTCSLPRSRFTRNMACALRICLLLCCLLCLECAPPHPHPLTW

Target ORF information:

RefSeq Version	XM_006525711.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006525711.4

ORF Insert Sequence:

ATGCGCGCGC ACCCGGGGGG AGGCCGCTGC TGCCCGGAGC AGGAGGAGGG GGAGAGCGCG 
GCGGGCGGCA GCGGCGCTGG CGGCGACTCC GCCATAGAGC AGGGGGGCCA GGGCAGCGCG 
CTCGCTCCGT CCCCGGTGAG CGGCGTGCGC AGGGAAGGCG CTCGGGGCGG CGGCCGTGGC 
CGGGGGCGGT GGAAGCAGGC GGCCCGGGGC GGCGGCGTCT GTGGCCGTGG CCGTGGCCGT 
GGCCGGGGTC GGGGCCGTGG CCGGGGCCGG GGCCGGGGCC GCGGCCGTCC CCAGAGTGGC 
GGCAGCGGCC TTGGCGGCGA CGGCGGCGGC GGCGCGGGCG GCTGCGGCGG CGGCAGCGGT 
GGCGGCGTCG CCCCCCGGCG GGATCCTGTC CCTTTCCCGT CGGGGAGCTC GGGGCCGGGG 
CCCAGGGGAC CCCGGGCCAC GGAGAGCGGG AAGAGGATGG ACTGCCCGGC CCTCCCCCCC 
GGATGGAAGA AGGAGGAAGT GATCCGAAAA TCAGGGCTCA GTGCTGGCAA GAGCGATGTC 
TACTACTTCA GTCCAAGTGG TAAGAAGTTC AGAAGTAAAC CTCAGCTGGC AAGATACCTG 
GGAAATGCTG TTGACCTTAG CAGTTTTGAC TTCAGGACCG GCAAGATGAT GCCTAGTAAA 
TTACAGAAGA ACAAGCAGAG ACTCCGGAAT GACCCCCTCA ATCAGAACAA GCCGCTCTGG 
ACCACTTGCT CGCTCCCTCG CTCGCGCTTC ACCCGCAACA TGGCATGCGC TCTCCGGATC 
TGCTTGCTTC TGTGCTGTCT CCTGTGCTTG GAATGTGCTC CCCCCCACCC TCACCCCCTG 
ACCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mbd2 ( NM_010773.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034903.2 Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu18158
Clone ID Related Accession (Same CDS sequence)	NM_010773.2
Accession Version	NM_010773.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1245bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-26
Organism	Mus musculus(house mouse)
Product	methyl-CpG-binding domain protein 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CX239662.1, AF072243.1, AK147008.1 and BU757659.1. On Dec 30, 2008 this sequence version replaced NM_010773.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC046607.1, AF072243.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGCGCGC ACCCGGGGGG AGGCCGCTGC TGCCCGGAGC AGGAGGAGGG GGAGAGCGCG 
GCGGGCGGCA GCGGCGCTGG CGGCGACTCC GCCATAGAGC AGGGGGGCCA GGGCAGCGCG 
CTCGCTCCGT CCCCGGTGAG CGGCGTGCGC AGGGAAGGCG CTCGGGGCGG CGGCCGTGGC 
CGGGGGCGGT GGAAGCAGGC GGCCCGGGGC GGCGGCGTCT GTGGCCGTGG CCGTGGCCGT 
GGCCGGGGTC GGGGCCGTGG CCGGGGCCGG GGCCGGGGCC GCGGCCGTCC CCAGAGTGGC 
GGCAGCGGCC TTGGCGGCGA CGGCGGCGGC GGCGCGGGCG GCTGCGGCGG CGGCAGCGGT 
GGCGGCGTCG CCCCCCGGCG GGATCCTGTC CCTTTCCCGT CGGGGAGCTC GGGGCCGGGG 
CCCAGGGGAC CCCGGGCCAC GGAGAGCGGG AAGAGGATGG ACTGCCCGGC CCTCCCCCCC 
GGATGGAAGA AGGAGGAAGT GATCCGAAAA TCAGGGCTCA GTGCTGGCAA GAGCGATGTC 
TACTACTTCA GTCCAAGTGG TAAGAAGTTC AGAAGTAAAC CTCAGCTGGC AAGATACCTG 
GGAAATGCTG TTGACCTTAG CAGTTTTGAC TTCAGGACCG GCAAGATGAT GCCTAGTAAA 
TTACAGAAGA ACAAGCAGAG ACTCCGGAAT GACCCCCTCA ATCAGAACAA GGGTAAACCA 
GACCTGAACA CAACATTGCC AATTAGACAA ACTGCATCAA TTTTCAAGCA ACCAGTAACC 
AAATTCACGA ACCACCCGAG CAATAAGGTG AAGTCAGACC CCCAGCGGAT GAATGAACAA 
CCACGTCAGC TTTTCTGGGA GAAGAGGCTA CAAGGACTTA GCGCATCAGA TGTAACAGAA 
CAAATTATAA AAACCATGGA GCTACCTAAA GGTCTTCAAG GAGTCGGTCC AGGTAGCAAT 
GACGAGACCC TTCTGTCTGC TGTGGCCAGT GCTTTACACA CAAGCTCTGC GCCCATCACA 
GGACAAGTCT CTGCTGCCGT GGAAAAGAAC CCTGCTGTTT GGCTTAACAC ATCTCAACCC 
CTCTGCAAAG CTTTCATTGT TACAGATGAA GACATTAGGA AACAGGAAGA GCGAGTCCAA 
CAAGTACGCA AGAAACTGGA GGAGGCACTG ATGGCCGACA TCCTGTCCCG GGCTGCGGAC 
ACGGAGGAAG TAGACATTGA CATGGACAGT GGAGATGAGG CGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034903.2
CDS	126..1370
Translation	MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAARGGGVCGRGRGRGRGRGRGRGRGRGRGRPQSGGSGLGGDGGGGAGGCGGGSGGGVAPRRDPVPFPSGSSGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNAVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKFTNHPSNKVKSDPQRMNEQPRQLFWEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQVSAAVEKNPAVWLNTSQPLCKAFIVTDEDIRKQEERVQQVRKKLEEALMADILSRAADTEEVDIDMDSGDEA

Target ORF information:

RefSeq Version	NM_010773.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010773.2

ORF Insert Sequence:

ATGCGCGCGC ACCCGGGGGG AGGCCGCTGC TGCCCGGAGC AGGAGGAGGG GGAGAGCGCG 
GCGGGCGGCA GCGGCGCTGG CGGCGACTCC GCCATAGAGC AGGGGGGCCA GGGCAGCGCG 
CTCGCTCCGT CCCCGGTGAG CGGCGTGCGC AGGGAAGGCG CTCGGGGCGG CGGCCGTGGC 
CGGGGGCGGT GGAAGCAGGC GGCCCGGGGC GGCGGCGTCT GTGGCCGTGG CCGTGGCCGT 
GGCCGGGGTC GGGGCCGTGG CCGGGGCCGG GGCCGGGGCC GCGGCCGTCC CCAGAGTGGC 
GGCAGCGGCC TTGGCGGCGA CGGCGGCGGC GGCGCGGGCG GCTGCGGCGG CGGCAGCGGT 
GGCGGCGTCG CCCCCCGGCG GGATCCTGTC CCTTTCCCGT CGGGGAGCTC GGGGCCGGGG 
CCCAGGGGAC CCCGGGCCAC GGAGAGCGGG AAGAGGATGG ACTGCCCGGC CCTCCCCCCC 
GGATGGAAGA AGGAGGAAGT GATCCGAAAA TCAGGGCTCA GTGCTGGCAA GAGCGATGTC 
TACTACTTCA GTCCAAGTGG TAAGAAGTTC AGAAGTAAAC CTCAGCTGGC AAGATACCTG 
GGAAATGCTG TTGACCTTAG CAGTTTTGAC TTCAGGACCG GCAAGATGAT GCCTAGTAAA 
TTACAGAAGA ACAAGCAGAG ACTCCGGAAT GACCCCCTCA ATCAGAACAA GGGTAAACCA 
GACCTGAACA CAACATTGCC AATTAGACAA ACTGCATCAA TTTTCAAGCA ACCAGTAACC 
AAATTCACGA ACCACCCGAG CAATAAGGTG AAGTCAGACC CCCAGCGGAT GAATGAACAA 
CCACGTCAGC TTTTCTGGGA GAAGAGGCTA CAAGGACTTA GCGCATCAGA TGTAACAGAA 
CAAATTATAA AAACCATGGA GCTACCTAAA GGTCTTCAAG GAGTCGGTCC AGGTAGCAAT 
GACGAGACCC TTCTGTCTGC TGTGGCCAGT GCTTTACACA CAAGCTCTGC GCCCATCACA 
GGACAAGTCT CTGCTGCCGT GGAAAAGAAC CCTGCTGTTT GGCTTAACAC ATCTCAACCC 
CTCTGCAAAG CTTTCATTGT TACAGATGAA GACATTAGGA AACAGGAAGA GCGAGTCCAA 
CAAGTACGCA AGAAACTGGA GGAGGCACTG ATGGCCGACA TCCTGTCCCG GGCTGCGGAC 
ACGGAGGAAG TAGACATTGA CATGGACAGT GGAGATGAGG CGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mbd2 ( NM_001311071.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001298000.1 Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu68185
Clone ID Related Accession (Same CDS sequence)	NM_001311071.1
Accession Version	NM_001311071.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 750bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-26
Organism	Mus musculus(house mouse)
Product	methyl-CpG-binding domain protein 2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CX239662.1, AF072245.1, AC134831.3 and BE953207.1. On Jul 21, 2015 this sequence version replaced XM_006525712.1. Transcript Variant: This variant (2) lacks part of the 3' coding region and uses an alternate 3'-terminal exon, compared to variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF072245.1, AK082825.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGCGCGC ACCCGGGGGG AGGCCGCTGC TGCCCGGAGC AGGAGGAGGG GGAGAGCGCG 
GCGGGCGGCA GCGGCGCTGG CGGCGACTCC GCCATAGAGC AGGGGGGCCA GGGCAGCGCG 
CTCGCTCCGT CCCCGGTGAG CGGCGTGCGC AGGGAAGGCG CTCGGGGCGG CGGCCGTGGC 
CGGGGGCGGT GGAAGCAGGC GGCCCGGGGC GGCGGCGTCT GTGGCCGTGG CCGTGGCCGT 
GGCCGGGGTC GGGGCCGTGG CCGGGGCCGG GGCCGGGGCC GCGGCCGTCC CCAGAGTGGC 
GGCAGCGGCC TTGGCGGCGA CGGCGGCGGC GGCGCGGGCG GCTGCGGCGG CGGCAGCGGT 
GGCGGCGTCG CCCCCCGGCG GGATCCTGTC CCTTTCCCGT CGGGGAGCTC GGGGCCGGGG 
CCCAGGGGAC CCCGGGCCAC GGAGAGCGGG AAGAGGATGG ACTGCCCGGC CCTCCCCCCC 
GGATGGAAGA AGGAGGAAGT GATCCGAAAA TCAGGGCTCA GTGCTGGCAA GAGCGATGTC 
TACTACTTCA GTCCAAGTGG TAAGAAGTTC AGAAGTAAAC CTCAGCTGGC AAGATACCTG 
GGAAATGCTG TTGACCTTAG CAGTTTTGAC TTCAGGACCG GCAAGATGAT GCCTAGTAAA 
TTACAGAAGA ACAAGCAGAG ACTCCGGAAT GACCCCCTCA ATCAGAACAA GTTCCGGCTC 
ATTAAGAAGC AGACACTAAT TGGTCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001298000.1
CDS	126..875
Translation	MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAARGGGVCGRGRGRGRGRGRGRGRGRGRGRPQSGGSGLGGDGGGGAGGCGGGSGGGVAPRRDPVPFPSGSSGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNAVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKFRLIKKQTLIGL

Target ORF information:

RefSeq Version	NM_001311071.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001311071.1

ORF Insert Sequence:

ATGCGCGCGC ACCCGGGGGG AGGCCGCTGC TGCCCGGAGC AGGAGGAGGG GGAGAGCGCG 
GCGGGCGGCA GCGGCGCTGG CGGCGACTCC GCCATAGAGC AGGGGGGCCA GGGCAGCGCG 
CTCGCTCCGT CCCCGGTGAG CGGCGTGCGC AGGGAAGGCG CTCGGGGCGG CGGCCGTGGC 
CGGGGGCGGT GGAAGCAGGC GGCCCGGGGC GGCGGCGTCT GTGGCCGTGG CCGTGGCCGT 
GGCCGGGGTC GGGGCCGTGG CCGGGGCCGG GGCCGGGGCC GCGGCCGTCC CCAGAGTGGC 
GGCAGCGGCC TTGGCGGCGA CGGCGGCGGC GGCGCGGGCG GCTGCGGCGG CGGCAGCGGT 
GGCGGCGTCG CCCCCCGGCG GGATCCTGTC CCTTTCCCGT CGGGGAGCTC GGGGCCGGGG 
CCCAGGGGAC CCCGGGCCAC GGAGAGCGGG AAGAGGATGG ACTGCCCGGC CCTCCCCCCC 
GGATGGAAGA AGGAGGAAGT GATCCGAAAA TCAGGGCTCA GTGCTGGCAA GAGCGATGTC 
TACTACTTCA GTCCAAGTGG TAAGAAGTTC AGAAGTAAAC CTCAGCTGGC AAGATACCTG 
GGAAATGCTG TTGACCTTAG CAGTTTTGAC TTCAGGACCG GCAAGATGAT GCCTAGTAAA 
TTACAGAAGA ACAAGCAGAG ACTCCGGAAT GACCCCCTCA ATCAGAACAA GTTCCGGCTC 
ATTAAGAAGC AGACACTAAT TGGTCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mbd2 ( XM_006525710.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006525773.1 Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu54427
Clone ID Related Accession (Same CDS sequence)	XM_006525710.3
Accession Version	XM_006525710.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 873bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	methyl-CpG-binding domain protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006525710.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGCGCGC ACCCGGGGGG AGGCCGCTGC TGCCCGGAGC AGGAGGAGGG GGAGAGCGCG 
GCGGGCGGCA GCGGCGCTGG CGGCGACTCC GCCATAGAGC AGGGGGGCCA GGGCAGCGCG 
CTCGCTCCGT CCCCGGTGAG CGGCGTGCGC AGGGAAGGCG CTCGGGGCGG CGGCCGTGGC 
CGGGGGCGGT GGAAGCAGGC GGCCCGGGGC GGCGGCGTCT GTGGCCGTGG CCGTGGCCGT 
GGCCGGGGTC GGGGCCGTGG CCGGGGCCGG GGCCGGGGCC GCGGCCGTCC CCAGAGTGGC 
GGCAGCGGCC TTGGCGGCGA CGGCGGCGGC GGCGCGGGCG GCTGCGGCGG CGGCAGCGGT 
GGCGGCGTCG CCCCCCGGCG GGATCCTGTC CCTTTCCCGT CGGGGAGCTC GGGGCCGGGG 
CCCAGGGGAC CCCGGGCCAC GGAGAGCGGG AAGAGGATGG ACTGCCCGGC CCTCCCCCCC 
GGATGGAAGA AGGAGGAAGT GATCCGAAAA TCAGGGCTCA GTGCTGGCAA GAGCGATGTC 
TACTACTTCA GTCCAAGTGG TAAGAAGTTC AGAAGTAAAC CTCAGCTGGC AAGATACCTG 
GGAAATGCTG TTGACCTTAG CAGTTTTGAC TTCAGGACCG GCAAGATGAT GCCTAGTAAA 
TTACAGAAGA ACAAGCAGAG ACTCCGGAAT GACCCCCTCA ATCAGAACAA GTTTGTGTGC 
ACCTCTCTGC TCCAGCCGCT CTGGACCACT TGCTCGCTCC CTCGCTCGCG CTTCACCCGC 
AACATGGCAT GCGCTCTCCG GATCTGCTTG CTTCTGTGCT GTCTCCTGTG CTTGGAATGT 
GCTCCCCCCC ACCCTCACCC CCTGACCTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006525773.1
CDS	149..1021
Translation	MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAARGGGVCGRGRGRGRGRGRGRGRGRGRGRPQSGGSGLGGDGGGGAGGCGGGSGGGVAPRRDPVPFPSGSSGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNAVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKFVCTSLLQPLWTTCSLPRSRFTRNMACALRICLLLCCLLCLECAPPHPHPLTW

Target ORF information:

RefSeq Version	XM_006525710.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006525710.3

ORF Insert Sequence:

ATGCGCGCGC ACCCGGGGGG AGGCCGCTGC TGCCCGGAGC AGGAGGAGGG GGAGAGCGCG 
GCGGGCGGCA GCGGCGCTGG CGGCGACTCC GCCATAGAGC AGGGGGGCCA GGGCAGCGCG 
CTCGCTCCGT CCCCGGTGAG CGGCGTGCGC AGGGAAGGCG CTCGGGGCGG CGGCCGTGGC 
CGGGGGCGGT GGAAGCAGGC GGCCCGGGGC GGCGGCGTCT GTGGCCGTGG CCGTGGCCGT 
GGCCGGGGTC GGGGCCGTGG CCGGGGCCGG GGCCGGGGCC GCGGCCGTCC CCAGAGTGGC 
GGCAGCGGCC TTGGCGGCGA CGGCGGCGGC GGCGCGGGCG GCTGCGGCGG CGGCAGCGGT 
GGCGGCGTCG CCCCCCGGCG GGATCCTGTC CCTTTCCCGT CGGGGAGCTC GGGGCCGGGG 
CCCAGGGGAC CCCGGGCCAC GGAGAGCGGG AAGAGGATGG ACTGCCCGGC CCTCCCCCCC 
GGATGGAAGA AGGAGGAAGT GATCCGAAAA TCAGGGCTCA GTGCTGGCAA GAGCGATGTC 
TACTACTTCA GTCCAAGTGG TAAGAAGTTC AGAAGTAAAC CTCAGCTGGC AAGATACCTG 
GGAAATGCTG TTGACCTTAG CAGTTTTGAC TTCAGGACCG GCAAGATGAT GCCTAGTAAA 
TTACAGAAGA ACAAGCAGAG ACTCCGGAAT GACCCCCTCA ATCAGAACAA GTTTGTGTGC 
ACCTCTCTGC TCCAGCCGCT CTGGACCACT TGCTCGCTCC CTCGCTCGCG CTTCACCCGC 
AACATGGCAT GCGCTCTCCG GATCTGCTTG CTTCTGTGCT GTCTCCTGTG CTTGGAATGT 
GCTCCCCCCC ACCCTCACCC CCTGACCTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mbd2 ( XM_006525711.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006525774.1 Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant X3, mRNA.

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CloneID	OMu54428
Clone ID Related Accession (Same CDS sequence)	XM_006525711.3 , XM_006525711.4
Accession Version	XM_006525711.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	methyl-CpG-binding domain protein 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006525711.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGCGCGC ACCCGGGGGG AGGCCGCTGC TGCCCGGAGC AGGAGGAGGG GGAGAGCGCG 
GCGGGCGGCA GCGGCGCTGG CGGCGACTCC GCCATAGAGC AGGGGGGCCA GGGCAGCGCG 
CTCGCTCCGT CCCCGGTGAG CGGCGTGCGC AGGGAAGGCG CTCGGGGCGG CGGCCGTGGC 
CGGGGGCGGT GGAAGCAGGC GGCCCGGGGC GGCGGCGTCT GTGGCCGTGG CCGTGGCCGT 
GGCCGGGGTC GGGGCCGTGG CCGGGGCCGG GGCCGGGGCC GCGGCCGTCC CCAGAGTGGC 
GGCAGCGGCC TTGGCGGCGA CGGCGGCGGC GGCGCGGGCG GCTGCGGCGG CGGCAGCGGT 
GGCGGCGTCG CCCCCCGGCG GGATCCTGTC CCTTTCCCGT CGGGGAGCTC GGGGCCGGGG 
CCCAGGGGAC CCCGGGCCAC GGAGAGCGGG AAGAGGATGG ACTGCCCGGC CCTCCCCCCC 
GGATGGAAGA AGGAGGAAGT GATCCGAAAA TCAGGGCTCA GTGCTGGCAA GAGCGATGTC 
TACTACTTCA GTCCAAGTGG TAAGAAGTTC AGAAGTAAAC CTCAGCTGGC AAGATACCTG 
GGAAATGCTG TTGACCTTAG CAGTTTTGAC TTCAGGACCG GCAAGATGAT GCCTAGTAAA 
TTACAGAAGA ACAAGCAGAG ACTCCGGAAT GACCCCCTCA ATCAGAACAA GCCGCTCTGG 
ACCACTTGCT CGCTCCCTCG CTCGCGCTTC ACCCGCAACA TGGCATGCGC TCTCCGGATC 
TGCTTGCTTC TGTGCTGTCT CCTGTGCTTG GAATGTGCTC CCCCCCACCC TCACCCCCTG 
ACCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006525774.1
CDS	149..997
Translation	MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAARGGGVCGRGRGRGRGRGRGRGRGRGRGRPQSGGSGLGGDGGGGAGGCGGGSGGGVAPRRDPVPFPSGSSGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNAVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKPLWTTCSLPRSRFTRNMACALRICLLLCCLLCLECAPPHPHPLTW

Target ORF information:

RefSeq Version	XM_006525711.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus methyl-CpG binding domain protein 2 (Mbd2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006525711.3

ORF Insert Sequence:

ATGCGCGCGC ACCCGGGGGG AGGCCGCTGC TGCCCGGAGC AGGAGGAGGG GGAGAGCGCG 
GCGGGCGGCA GCGGCGCTGG CGGCGACTCC GCCATAGAGC AGGGGGGCCA GGGCAGCGCG 
CTCGCTCCGT CCCCGGTGAG CGGCGTGCGC AGGGAAGGCG CTCGGGGCGG CGGCCGTGGC 
CGGGGGCGGT GGAAGCAGGC GGCCCGGGGC GGCGGCGTCT GTGGCCGTGG CCGTGGCCGT 
GGCCGGGGTC GGGGCCGTGG CCGGGGCCGG GGCCGGGGCC GCGGCCGTCC CCAGAGTGGC 
GGCAGCGGCC TTGGCGGCGA CGGCGGCGGC GGCGCGGGCG GCTGCGGCGG CGGCAGCGGT 
GGCGGCGTCG CCCCCCGGCG GGATCCTGTC CCTTTCCCGT CGGGGAGCTC GGGGCCGGGG 
CCCAGGGGAC CCCGGGCCAC GGAGAGCGGG AAGAGGATGG ACTGCCCGGC CCTCCCCCCC 
GGATGGAAGA AGGAGGAAGT GATCCGAAAA TCAGGGCTCA GTGCTGGCAA GAGCGATGTC 
TACTACTTCA GTCCAAGTGG TAAGAAGTTC AGAAGTAAAC CTCAGCTGGC AAGATACCTG 
GGAAATGCTG TTGACCTTAG CAGTTTTGAC TTCAGGACCG GCAAGATGAT GCCTAGTAAA 
TTACAGAAGA ACAAGCAGAG ACTCCGGAAT GACCCCCTCA ATCAGAACAA GCCGCTCTGG 
ACCACTTGCT CGCTCCCTCG CTCGCGCTTC ACCCGCAACA TGGCATGCGC TCTCCGGATC 
TGCTTGCTTC TGTGCTGTCT CCTGTGCTTG GAATGTGCTC CCCCCCACCC TCACCCCCTG 
ACCTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MBD2 ablation impairs lymphopoiesis and impedes progression and maintenance of T-ALL.
Cancer research(2018 Jan)
Zhou M,Zhou K,Cheng L,Chen X,Wang J,Wang XM,Zhang Y,Yu Q,Zhang S,Wang D,Huang L,Huang M,Ma D,Cheng T,Wang CY,Yuan W,Zhou J

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Mbd2 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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