Marco cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Marco
Entrez Gene ID	17167
Full Name	macrophage receptor with collagenous structure
Synonyms	AI323439,Ly112,Scara2
General protein information	Preferred Names macrophage receptor with collagenous structure Names macrophage receptor MARCO
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 E2.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_010766.3	NP_034896.1	macrophage receptor MARCO
NM_010766.2	NP_034896.1	macrophage receptor MARCO

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MARCO	XP_515756.1
Canis lupus familiaris (dog)	MARCO	XP_005631974.1
Rattus norvegicus (Norway rat)	Marco	NP_001102481.1
Gallus gallus (chicken)	MARCO	NP_990067.1
Danio rerio (zebrafish)	LOC571584	XP_005169179.1
Xenopus tropicalis (tropical clawed frog)	LOC100492872	XP_002944607.1
	MARCO	XP_001083118.1
Homo sapiens (human)	MARCO	NP_006761.1
Mus musculus (house mouse)	Marco	NP_034896.1

Gene Ontology
Bibliography

Related articles in PubMed

Key Role of the Scavenger Receptor MARCO in Mediating Adenovirus Infection and Subsequent Innate Responses of Macrophages.
Maler MD, Nielsen PJ, Stichling N, Cohen I, Ruzsics Z, Wood C, Engelhard P, Suomalainen M, Gyory I, Huber M, M?ller-Quernheim J, Schamel WWA, Gordon S, Jakob T, Martin SF, Jahnen-Dechent W, Greber UF, Freudenberg MA, Fejer G
mBio8(4)(2017 Aug)

Immunomodulators targeting MARCO expression improve resistance to postinfluenza bacterial pneumonia.
Wu M, Gibbons JG, DeLoid GM, Bedugnis AS, Thimmulappa RK, Biswal S, Kobzik L
American journal of physiology. Lung cellular and molecular physiology313(1)L138-L153(2017 Jul)

MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1.
Shichita T, Ito M, Morita R, Komai K, Noguchi Y, Ooboshi H, Koshida R, Takahashi S, Kodama T, Yoshimura A
Nature medicine23(6)723-732(2017 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Increasing MARCO expression by targeting Nrf2 signaling or the Akt-TFEB-MARCO pathway are promising strategies to improve bacterial clearance and survival in postinfluenza bacterial pneumonia.
Title: Immunomodulators targeting MARCO expression improve resistance to postinfluenza bacterial pneumonia.

Common damage-associated molecular patterns (DAMPs) were internalized through the class A scavenger receptors MSR1 and MARCO in vitro. In ischemic murine brain, DAMP internalization was largely mediated by MSR1. Combined deficiency for Msr1 and Marco in infiltrating myeloid cells caused impaired clearance of DAMPs, more severe inflammation, and exacerbated neuronal injury in a murine model of ischemic stroke.
Title: MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1.

free actin likely contributes to impaired host defense by blocking scavenger receptor binding of bacteria.
Title: Free actin impairs macrophage bacterial defenses via scavenger receptor MARCO interaction with reversal by plasma gelsolin.

this study shows that Marco functions as co-receptor along with TLRs for HMGB1 in M1-type inflammatory macrophages
Title: Role of scavenger receptors as damage-associated molecular pattern receptors in Toll-like receptor activation.

MARCO Is Processed by either Macropinocytosis or Endocytosis-Autophagy Pathway
Title: Macrophage Receptor with Collagenous Structure (MARCO) Is Processed by either Macropinocytosis or Endocytosis-Autophagy Pathway.

The following Marco gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Marco cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu06829	NM_010766.3 Latest version!	Mus musculus macrophage receptor with collagenous structure (Marco), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$300.30 $429.00
View Old Accession Versions >>
OMu06829	NM_010766.2	Mus musculus macrophage receptor with collagenous structure (Marco), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$300.30 $429.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Marco ( NM_010766.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034896.1 Mus musculus macrophage receptor with collagenous structure (Marco), mRNA.

Price & Availability↑

CloneID	OMu06829
Clone ID Related Accession (Same CDS sequence)	NM_010766.3 , NM_010766.2
Accession Version	NM_010766.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1557bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Mus musculus(house mouse)
Product	macrophage receptor MARCO
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC132338.1 and AA185896.1. On Feb 14, 2018 this sequence version replaced NM_010766.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC137939.1, AK169230.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAAGTA AAGAACTCCT CAAAGAGGAA GACTTCTTGG GCAGCACAGA AGACAGAGCC 
GATTTTGACC AAGCTATGTT CCCTGTGATG GAGACCTTCG AAATCAATGA TCCAGTGCCC 
AAGAAGAGAA ATGGGGGGAC CTTCTGCATG GCAGTCATGG CCATCCACCT GATCCTGCTC 
ACGGCAGGTA CTGCACTGCT GCTGATTCAA GTTCTCAATC TGCAGGAGCA GCTCCAGATG 
CTAGAGATGT GCTGTGGCAA TGGATCACTA GCTATCGAGG ACAAGCCCTT CTTCTCGCTG 
CAGTGGGCAC CCAAAACACA CCTGGTACCT AGAGCACAGG GGCTGCAAGC CTTGCAGGCC 
CAGCTCAGCT GGGTCCATAC CAGCCAGGAG CAACTCCGTC AGCAGTTCAA CAACCTCACT 
CAAAATCCAG AGTTGTTCCA GATTAAAGGT GAACGAGGCT CTCCAGGTCC AAAAGGGGCC 
CCGGGTGCTC CTGGAATCCC CGGGCTGCCT GGGCCAGCTG CTGAGAAGGG AGAAAAGGGG 
GCTGCAGGTC GTGATGGAAC CCCAGGTGTC CAAGGACCCC AGGGCCCACC AGGCAGCAAG 
GGAGAGGCAG GCCTCCAGGG ACTTACGGGT GCACCAGGGA AGCAAGGAGC AACTGGTGCT 
CCAGGACCTC GAGGAGAGAA GGGCAGCAAA GGTGACATAG GTCTCACTGG CCCCAAGGGG 
GAACATGGCA CCAAGGGAGA CAAAGGGGAC CTAGGCCTTC CAGGAAACAA AGGGGACATG 
GGCATGAAGG GAGACACGGG GCCCATGGGG TCCCCTGGAG CTCAGGGAGG TAAAGGTGAT 
GCTGGAAAAC CAGGCCTACC AGGTTTGGCT GGATCTCCAG GAGTCAAAGG TGACCAAGGA 
AAACCTGGAG TGCAGGGTGT TCCAGGCCCT CAAGGTGCAC CAGGACTTTC AGGTGCCAAG 
GGTGAGCCAG GACGCACTGG TCTTCCTGGG CCAGCAGGAC CCCCGGGAAT TGCTGGGAAT 
CCAGGGATTG CAGGTGTGAA AGGAAGCAAG GGTGACACAG GAATTCAAGG ACAGAAAGGC 
ACAAAAGGAG AATCAGGAGT CCCAGGTCTT GTAGGCAGAA AGGGAGACAC TGGAAGCCCT 
GGGCTGGCAG GTCCCAAAGG AGAACCTGGA CGAGTCGGTC AGAAGGGAGA CCCGGGGATG 
AAAGGGTCTT CTGGCCAGCA AGGACAAAAG GGAGAAAAGG GTCAAAAAGG CGAATCTTTC 
CAACGCGTCC GGATCATGGG TGGCACCAAC AGAGGCCGAG CTGAAGTTTA CTATAACAAT 
GAGTGGGGGA CAATTTGTGA TGATGATTGG GATAATAATG ATGCGACTGT CTTCTGTCGC 
ATGCTCGGTT ACTCCAGAGG GAGAGCACTT AGCAGCTATG GAGGTGGCTC TGGGAACATC 
TGGCTGGACA ATGTGAATTG TCGGGGCACA GAGAACAGTT TGTGGGACTG CAGTAAGAAC 
TCCTGGGGCA ATCACAATTG CGTACATAAT GAAGATGCGG GTGTGGAATG CTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034896.1
CDS	248..1804
Translation	MGSKELLKEEDFLGSTEDRADFDQAMFPVMETFEINDPVPKKRNGGTFCMAVMAIHLILLTAGTALLLIQVLNLQEQLQMLEMCCGNGSLAIEDKPFFSLQWAPKTHLVPRAQGLQALQAQLSWVHTSQEQLRQQFNNLTQNPELFQIKGERGSPGPKGAPGAPGIPGLPGPAAEKGEKGAAGRDGTPGVQGPQGPPGSKGEAGLQGLTGAPGKQGATGAPGPRGEKGSKGDIGLTGPKGEHGTKGDKGDLGLPGNKGDMGMKGDTGPMGSPGAQGGKGDAGKPGLPGLAGSPGVKGDQGKPGVQGVPGPQGAPGLSGAKGEPGRTGLPGPAGPPGIAGNPGIAGVKGSKGDTGIQGQKGTKGESGVPGLVGRKGDTGSPGLAGPKGEPGRVGQKGDPGMKGSSGQQGQKGEKGQKGESFQRVRIMGGTNRGRAEVYYNNEWGTICDDDWDNNDATVFCRMLGYSRGRALSSYGGGSGNIWLDNVNCRGTENSLWDCSKNSWGNHNCVHNEDAGVECS

Target ORF information:

RefSeq Version	NM_010766.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus macrophage receptor with collagenous structure (Marco), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010766.3

ORF Insert Sequence:

ATGGGAAGTA AAGAACTCCT CAAAGAGGAA GACTTCTTGG GCAGCACAGA AGACAGAGCC 
GATTTTGACC AAGCTATGTT CCCTGTGATG GAGACCTTCG AAATCAATGA TCCAGTGCCC 
AAGAAGAGAA ATGGGGGGAC CTTCTGCATG GCAGTCATGG CCATCCACCT GATCCTGCTC 
ACGGCAGGTA CTGCACTGCT GCTGATTCAA GTTCTCAATC TGCAGGAGCA GCTCCAGATG 
CTAGAGATGT GCTGTGGCAA TGGATCACTA GCTATCGAGG ACAAGCCCTT CTTCTCGCTG 
CAGTGGGCAC CCAAAACACA CCTGGTACCT AGAGCACAGG GGCTGCAAGC CTTGCAGGCC 
CAGCTCAGCT GGGTCCATAC CAGCCAGGAG CAACTCCGTC AGCAGTTCAA CAACCTCACT 
CAAAATCCAG AGTTGTTCCA GATTAAAGGT GAACGAGGCT CTCCAGGTCC AAAAGGGGCC 
CCGGGTGCTC CTGGAATCCC CGGGCTGCCT GGGCCAGCTG CTGAGAAGGG AGAAAAGGGG 
GCTGCAGGTC GTGATGGAAC CCCAGGTGTC CAAGGACCCC AGGGCCCACC AGGCAGCAAG 
GGAGAGGCAG GCCTCCAGGG ACTTACGGGT GCACCAGGGA AGCAAGGAGC AACTGGTGCT 
CCAGGACCTC GAGGAGAGAA GGGCAGCAAA GGTGACATAG GTCTCACTGG CCCCAAGGGG 
GAACATGGCA CCAAGGGAGA CAAAGGGGAC CTAGGCCTTC CAGGAAACAA AGGGGACATG 
GGCATGAAGG GAGACACGGG GCCCATGGGG TCCCCTGGAG CTCAGGGAGG TAAAGGTGAT 
GCTGGAAAAC CAGGCCTACC AGGTTTGGCT GGATCTCCAG GAGTCAAAGG TGACCAAGGA 
AAACCTGGAG TGCAGGGTGT TCCAGGCCCT CAAGGTGCAC CAGGACTTTC AGGTGCCAAG 
GGTGAGCCAG GACGCACTGG TCTTCCTGGG CCAGCAGGAC CCCCGGGAAT TGCTGGGAAT 
CCAGGGATTG CAGGTGTGAA AGGAAGCAAG GGTGACACAG GAATTCAAGG ACAGAAAGGC 
ACAAAAGGAG AATCAGGAGT CCCAGGTCTT GTAGGCAGAA AGGGAGACAC TGGAAGCCCT 
GGGCTGGCAG GTCCCAAAGG AGAACCTGGA CGAGTCGGTC AGAAGGGAGA CCCGGGGATG 
AAAGGGTCTT CTGGCCAGCA AGGACAAAAG GGAGAAAAGG GTCAAAAAGG CGAATCTTTC 
CAACGCGTCC GGATCATGGG TGGCACCAAC AGAGGCCGAG CTGAAGTTTA CTATAACAAT 
GAGTGGGGGA CAATTTGTGA TGATGATTGG GATAATAATG ATGCGACTGT CTTCTGTCGC 
ATGCTCGGTT ACTCCAGAGG GAGAGCACTT AGCAGCTATG GAGGTGGCTC TGGGAACATC 
TGGCTGGACA ATGTGAATTG TCGGGGCACA GAGAACAGTT TGTGGGACTG CAGTAAGAAC 
TCCTGGGGCA ATCACAATTG CGTACATAAT GAAGATGCGG GTGTGGAATG CTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Marco ( NM_010766.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034896.1 Mus musculus macrophage receptor with collagenous structure (Marco), mRNA.

Price & Availability↑

CloneID	OMu06829
Clone ID Related Accession (Same CDS sequence)	NM_010766.3 , NM_010766.2
Accession Version	NM_010766.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1557bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Mus musculus(house mouse)
Product	macrophage receptor MARCO
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC125340.3. On Nov 17, 2006 this sequence version replaced NM_010766.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U18424.1, BC137939.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135 [ECO:0000348] ##Evidence-Data-END##

ATGGGAAGTA AAGAACTCCT CAAAGAGGAA GACTTCTTGG GCAGCACAGA AGACAGAGCC 
GATTTTGACC AAGCTATGTT CCCTGTGATG GAGACCTTCG AAATCAATGA TCCAGTGCCC 
AAGAAGAGAA ATGGGGGGAC CTTCTGCATG GCAGTCATGG CCATCCACCT GATCCTGCTC 
ACGGCAGGTA CTGCACTGCT GCTGATTCAA GTTCTCAATC TGCAGGAGCA GCTCCAGATG 
CTAGAGATGT GCTGTGGCAA TGGATCACTA GCTATCGAGG ACAAGCCCTT CTTCTCGCTG 
CAGTGGGCAC CCAAAACACA CCTGGTACCT AGAGCACAGG GGCTGCAAGC CTTGCAGGCC 
CAGCTCAGCT GGGTCCATAC CAGCCAGGAG CAACTCCGTC AGCAGTTCAA CAACCTCACT 
CAAAATCCAG AGTTGTTCCA GATTAAAGGT GAACGAGGCT CTCCAGGTCC AAAAGGGGCC 
CCGGGTGCTC CTGGAATCCC CGGGCTGCCT GGGCCAGCTG CTGAGAAGGG AGAAAAGGGG 
GCTGCAGGTC GTGATGGAAC CCCAGGTGTC CAAGGACCCC AGGGCCCACC AGGCAGCAAG 
GGAGAGGCAG GCCTCCAGGG ACTTACGGGT GCACCAGGGA AGCAAGGAGC AACTGGTGCT 
CCAGGACCTC GAGGAGAGAA GGGCAGCAAA GGTGACATAG GTCTCACTGG CCCCAAGGGG 
GAACATGGCA CCAAGGGAGA CAAAGGGGAC CTAGGCCTTC CAGGAAACAA AGGGGACATG 
GGCATGAAGG GAGACACGGG GCCCATGGGG TCCCCTGGAG CTCAGGGAGG TAAAGGTGAT 
GCTGGAAAAC CAGGCCTACC AGGTTTGGCT GGATCTCCAG GAGTCAAAGG TGACCAAGGA 
AAACCTGGAG TGCAGGGTGT TCCAGGCCCT CAAGGTGCAC CAGGACTTTC AGGTGCCAAG 
GGTGAGCCAG GACGCACTGG TCTTCCTGGG CCAGCAGGAC CCCCGGGAAT TGCTGGGAAT 
CCAGGGATTG CAGGTGTGAA AGGAAGCAAG GGTGACACAG GAATTCAAGG ACAGAAAGGC 
ACAAAAGGAG AATCAGGAGT CCCAGGTCTT GTAGGCAGAA AGGGAGACAC TGGAAGCCCT 
GGGCTGGCAG GTCCCAAAGG AGAACCTGGA CGAGTCGGTC AGAAGGGAGA CCCGGGGATG 
AAAGGGTCTT CTGGCCAGCA AGGACAAAAG GGAGAAAAGG GTCAAAAAGG CGAATCTTTC 
CAACGCGTCC GGATCATGGG TGGCACCAAC AGAGGCCGAG CTGAAGTTTA CTATAACAAT 
GAGTGGGGGA CAATTTGTGA TGATGATTGG GATAATAATG ATGCGACTGT CTTCTGTCGC 
ATGCTCGGTT ACTCCAGAGG GAGAGCACTT AGCAGCTATG GAGGTGGCTC TGGGAACATC 
TGGCTGGACA ATGTGAATTG TCGGGGCACA GAGAACAGTT TGTGGGACTG CAGTAAGAAC 
TCCTGGGGCA ATCACAATTG CGTACATAAT GAAGATGCGG GTGTGGAATG CTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034896.1
CDS	308..1864
Translation	MGSKELLKEEDFLGSTEDRADFDQAMFPVMETFEINDPVPKKRNGGTFCMAVMAIHLILLTAGTALLLIQVLNLQEQLQMLEMCCGNGSLAIEDKPFFSLQWAPKTHLVPRAQGLQALQAQLSWVHTSQEQLRQQFNNLTQNPELFQIKGERGSPGPKGAPGAPGIPGLPGPAAEKGEKGAAGRDGTPGVQGPQGPPGSKGEAGLQGLTGAPGKQGATGAPGPRGEKGSKGDIGLTGPKGEHGTKGDKGDLGLPGNKGDMGMKGDTGPMGSPGAQGGKGDAGKPGLPGLAGSPGVKGDQGKPGVQGVPGPQGAPGLSGAKGEPGRTGLPGPAGPPGIAGNPGIAGVKGSKGDTGIQGQKGTKGESGVPGLVGRKGDTGSPGLAGPKGEPGRVGQKGDPGMKGSSGQQGQKGEKGQKGESFQRVRIMGGTNRGRAEVYYNNEWGTICDDDWDNNDATVFCRMLGYSRGRALSSYGGGSGNIWLDNVNCRGTENSLWDCSKNSWGNHNCVHNEDAGVECS

Target ORF information:

RefSeq Version	NM_010766.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus macrophage receptor with collagenous structure (Marco), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010766.2

ORF Insert Sequence:

ATGGGAAGTA AAGAACTCCT CAAAGAGGAA GACTTCTTGG GCAGCACAGA AGACAGAGCC 
GATTTTGACC AAGCTATGTT CCCTGTGATG GAGACCTTCG AAATCAATGA TCCAGTGCCC 
AAGAAGAGAA ATGGGGGGAC CTTCTGCATG GCAGTCATGG CCATCCACCT GATCCTGCTC 
ACGGCAGGTA CTGCACTGCT GCTGATTCAA GTTCTCAATC TGCAGGAGCA GCTCCAGATG 
CTAGAGATGT GCTGTGGCAA TGGATCACTA GCTATCGAGG ACAAGCCCTT CTTCTCGCTG 
CAGTGGGCAC CCAAAACACA CCTGGTACCT AGAGCACAGG GGCTGCAAGC CTTGCAGGCC 
CAGCTCAGCT GGGTCCATAC CAGCCAGGAG CAACTCCGTC AGCAGTTCAA CAACCTCACT 
CAAAATCCAG AGTTGTTCCA GATTAAAGGT GAACGAGGCT CTCCAGGTCC AAAAGGGGCC 
CCGGGTGCTC CTGGAATCCC CGGGCTGCCT GGGCCAGCTG CTGAGAAGGG AGAAAAGGGG 
GCTGCAGGTC GTGATGGAAC CCCAGGTGTC CAAGGACCCC AGGGCCCACC AGGCAGCAAG 
GGAGAGGCAG GCCTCCAGGG ACTTACGGGT GCACCAGGGA AGCAAGGAGC AACTGGTGCT 
CCAGGACCTC GAGGAGAGAA GGGCAGCAAA GGTGACATAG GTCTCACTGG CCCCAAGGGG 
GAACATGGCA CCAAGGGAGA CAAAGGGGAC CTAGGCCTTC CAGGAAACAA AGGGGACATG 
GGCATGAAGG GAGACACGGG GCCCATGGGG TCCCCTGGAG CTCAGGGAGG TAAAGGTGAT 
GCTGGAAAAC CAGGCCTACC AGGTTTGGCT GGATCTCCAG GAGTCAAAGG TGACCAAGGA 
AAACCTGGAG TGCAGGGTGT TCCAGGCCCT CAAGGTGCAC CAGGACTTTC AGGTGCCAAG 
GGTGAGCCAG GACGCACTGG TCTTCCTGGG CCAGCAGGAC CCCCGGGAAT TGCTGGGAAT 
CCAGGGATTG CAGGTGTGAA AGGAAGCAAG GGTGACACAG GAATTCAAGG ACAGAAAGGC 
ACAAAAGGAG AATCAGGAGT CCCAGGTCTT GTAGGCAGAA AGGGAGACAC TGGAAGCCCT 
GGGCTGGCAG GTCCCAAAGG AGAACCTGGA CGAGTCGGTC AGAAGGGAGA CCCGGGGATG 
AAAGGGTCTT CTGGCCAGCA AGGACAAAAG GGAGAAAAGG GTCAAAAAGG CGAATCTTTC 
CAACGCGTCC GGATCATGGG TGGCACCAAC AGAGGCCGAG CTGAAGTTTA CTATAACAAT 
GAGTGGGGGA CAATTTGTGA TGATGATTGG GATAATAATG ATGCGACTGT CTTCTGTCGC 
ATGCTCGGTT ACTCCAGAGG GAGAGCACTT AGCAGCTATG GAGGTGGCTC TGGGAACATC 
TGGCTGGACA ATGTGAATTG TCGGGGCACA GAGAACAGTT TGTGGGACTG CAGTAAGAAC 
TCCTGGGGCA ATCACAATTG CGTACATAAT GAAGATGCGG GTGTGGAATG CTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Key Role of the Scavenger Receptor MARCO in Mediating Adenovirus Infection and Subsequent Innate Responses of Macrophages.
mBio8(4)(2017 Aug)
Maler MD,Nielsen PJ,Stichling N,Cohen I,Ruzsics Z,Wood C,Engelhard P,Suomalainen M,Gyory I,Huber M,M?ller-Quernheim J,Schamel WWA,Gordon S,Jakob T,Martin SF,Jahnen-Dechent W,Greber UF,Freudenberg MA,Fejer G

Immunomodulators targeting MARCO expression improve resistance to postinfluenza bacterial pneumonia.
American journal of physiology. Lung cellular and molecular physiology313(1)L138-L153(2017 Jul)
Wu M,Gibbons JG,DeLoid GM,Bedugnis AS,Thimmulappa RK,Biswal S,Kobzik L

MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1.
Nature medicine23(6)723-732(2017 Jun)
Shichita T,Ito M,Morita R,Komai K,Noguchi Y,Ooboshi H,Koshida R,Takahashi S,Kodama T,Yoshimura A

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Marco cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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