Slc26a6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc26a6
Entrez Gene ID	171429
Full Name	solute carrier family 26, member 6
Synonyms	B930010B04Rik,CFEX,Pat-1,Pat1
General protein information	Preferred Names solute carrier family 26, member 6 Names solute carrier family 26 member 6 anion exchange transporter chloride-formate exchanger pendrin-L1 pendrin-like protein 1 putative anion transporter-1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 F2

mRNA and Protein(s)

mRNA	Protein	Name
NM_134420.4	NP_599252.2	solute carrier family 26 member 6

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLC26A6	XP_003309836.1
Danio rerio (zebrafish)	slc26a6l	NP_001107889.1
Danio rerio (zebrafish)	si:ch211-117c9.2	XP_685992.2
Canis lupus familiaris (dog)	SLC26A6	XP_005632639.1
Bos taurus (cattle)	SLC26A6	NP_001070320.1
Arabidopsis thaliana (thale cress)	SULTR4;1	NP_196859.1
Xenopus tropicalis (tropical clawed frog)	slc26a6	NP_001072916.2
Homo sapiens (human)	SLC26A6	NP_599025.2
Mus musculus (house mouse)	Slc26a6	NP_599252.2
Gallus gallus (chicken)	SLC26A6	NP_001239183.1
Danio rerio (zebrafish)	slc26a6	XP_001344243.4
Oryza sativa (rice)	Os09g0240500	NP_001062644.1
Rattus norvegicus (Norway rat)	Slc26a6	NP_001137289.1
Arabidopsis thaliana (thale cress)	SULTR4;2	NP_187858.1

Gene Ontology
Bibliography

Related articles in PubMed

Action Potential Shortening and Impairment of Cardiac Function by Ablation of
Sirish P, Ledford HA, Timofeyev V, Thai PN, Ren L, Kim HJ, Park S, Lee JH, Dai G, Moshref M, Sihn CR, Chen WC, Timofeyeva MV, Jian Z, Shimkunas R, Izu LT, Chiamvimonvat N, Chen-Izu Y, Yamoah EN, Zhang XD
Circulation. Arrhythmia and electrophysiology10(10)(2017 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Slc26a6 is a unique cardiac electrogenic Cl(-)/HCO3(-) transporter in ventricular myocytes, which has roles in regulating pHi, excitability, and contractility.
Title: Action Potential Shortening and Impairment of Cardiac Function by Ablation of

This study showed that transepithelial sulfate fluxes across the mouse distal ileum demonstrating that DRA (and to a lesser extent, PAT1) secretes sulfate with significant implications for intestinal sulfate absorption and overall homeostasis.
Title: Loss of the anion exchanger DRA (Slc26a3), or PAT1 (Slc26a6), alters sulfate transport by the distal ileum and overall sulfate homeostasis.

Enzymatic deglycosylation of SLC26A6 expressed on the plasma membrane of intact cells strongly reduced oxalate transport activity.
Title: N-glycosylation critically regulates function of oxalate transporter SLC26A6.

expressed in ameloblasts but not alone critical for formation of dental enamel
Title: Slc26a3/Dra and Slc26a6 in Murine Ameloblasts.

Slc26a1, Slc26a6 and Slc26a7 are novel participants in the extracellular transport of bicarbonate during enamel maturation.
Title: SLC26A Gene Family Participate in pH Regulation during Enamel Maturation.

The following Slc26a6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc26a6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu22405	NM_134420.4 Latest version!	Mus musculus solute carrier family 26, member 6 (Slc26a6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$433.30 $619.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc26a6 ( NM_134420.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_599252.2 Mus musculus solute carrier family 26, member 6 (Slc26a6), mRNA.

Price & Availability↑

CloneID	OMu22405
Clone ID Related Accession (Same CDS sequence)	NM_134420.4
Accession Version	NM_134420.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2208bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Mus musculus(house mouse)
Product	solute carrier family 26 member 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK163671.1, AK029238.1 and AF248494.1. On Oct 17, 2007 this sequence version replaced NM_134420.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGAGCTGC AGAGGAGAGA CTACCATGTG GAAAGGCCAT TGCTGAACCA GGAGCAGCTA 
GAAGATCTGG GGCATTGGGG CCCAGCGGCG AAGACCCACC AGTGGCGAAC TTGGTTCCGA 
TGCTCCCGTG CTCGGGCCCA TTCTCTTCTG CTCCAGCACG TTCCAGTCCT GGGCTGGTTA 
CCCCGGTATC CTGTGCGTGA ATGGCTCCTG GGTGATCTGT TATCTGGCCT GAGTGTGGCC 
ATCATGCAGC TTCCTCAGGG CTTGGCCTAT GCCCTTCTGG CGGGATTGCC TCCTATGTTT 
GGTCTGTACA GTTCTTTCTA CCCCGTCTTC ATCTACTTCC TGTTTGGTAC CTCCAGACAC 
ATCTCTGTGG GGACCTTTGC TGTAATGTCT GTGATGGTGG GCAGTGTGAC AGAATCTCTG 
ACAGCAGATA AGGCCTTCGT GCAAGGCTTG AATGCCACAG CTGATGATGC ACGCGTGCAG 
GTGGCCTACA CACTCAGCTT CCTGGTCGGC CTCTTCCAGG TGGGGCTGGG CCTGGTACAC 
TTCGGCTTCG TTGTCACCTA CCTGTCAGAG CCTCTGGTCC GCAGCTATAC CACGGCTGCA 
TCTGTGCAAG TCCTCGTCTC TCAGCTCAAG TATGTGTTTG GCATCAAACT CAGCAGTCAC 
TCTGGGCCAC TGTCCGTTAT CTATACAGTG CTGGAGGTCT GTGCCCAGCT CCCTGAGACT 
GTGCCCGGCA CCGTGGTCAC GGCGATTGTG GCAGGAGTGG CCTTGGTACT GGTGAAGCTA 
CTTAATGAGA AGCTGCATCG GCGTCTGCCC CTGCCCATCC CTGGGGAACT ACTCACGCTC 
ATTGGGGCCA CTGGTATTTC CTATGGTGTG AAGCTGAATG ACAGATTCAA GGTCGATGTG 
GTGGGCAACA TCACCACAGG GCTCATACCC CCGGTGGCAC CCAAGACAGA GCTGTTTGCA 
ACGCTTGTGG GAAATGCCTT TGCCATTGCT GTGGTGGGCT TCGCCATTGC CATCTCACTG 
GGGAAGATCT TTGCCCTGAG GCATGGCTAC CGTGTGGACA GTAACCAGGA GCTGGTAGCC 
CTTGGCCTCA GTAACCTCAT TGGAGGCTTC TTCCAGTGCT TCCCCGTGAG CTGCTCCATG 
TCTCGGAGCT TGGTACAGGA GAGCACGGGA GGCAACACAC AGGTTGCTGG AGCTGTATCT 
TCCCTTTTTA TCCTTCTTAT TATCGTCAAA CTTGGGGAAC TCTTCCGAGA CCTGCCCAAG 
GCCGTCCTGG CTGCTGTCAT TATTGTGAAC CTAAAGGGCA TGATGAAGCA GTTCTCAGAC 
ATCTGCTCTC TTTGGAAGGC AAACAGAGTG GACCTGCTAA TCTGGCTGGT GACCTTTGTG 
GCCACAATCC TGCTGAACCT GGACATTGGC CTGGCAGTTT CCATAGTCTT CTCCTTGCTG 
CTCGTGGTCG TCCGAATGCA GCTGCCCCAT TACTCCGTCC TGGGGCAGGT GCCAGATACG 
GATATTTATA GAGACGTGGC AGAATACTCT GGGGCCAAGG AGGTCCCGGG TGTGAAAGTC 
TTCCGTTCCT CAGCCACGCT GTACTTCGCC AATGCTGAGC TCTACAGCGA CTCTCTGAAA 
GAGAAGTGCG GTGTAGATGT TGACCGCCTC ATCACCCAGA AGAAGAAACG AATCAAAAAG 
CAGGAGATGA AGTTAAAGCG AATGAAGAAA GCCAAGAAGT CCCAGAAACA GGATGCTTCT 
TCCAAGATCT CCTCAGTTTC CGTCAACGTC AACACCAACT TGGAAGACGT CAAAAGCAAT 
GACGTCGAGG GCTCTGAGGC CAAGGTGCAC CAAGGGGAGG AGCTTCAGGA TGTAGTCTCC 
AGCAATCAAG AAGATGCCAA GGCCCCAACC ATGACCTCAC TGAAGTCCCT GGGCCTGCCT 
CAGCCAGGCT TCCATAGCCT CATCCTGGAC CTGAGCACCC TCTCCTTTGT GGACACTGTG 
TGCATTAAGA GCCTGAAGAA TATTTTCCGT GACTTCCGGG AGATTGAAGT GGAAGTGTAC 
ATCGCAGCCT GTTACAGTCC TGTGGTCGCC CAGCTTGAAG CTGGACACTT CTTTGATGAA 
TCTATCACTA AGCAGCATGT CTTTGCCTCT GTCCATGACG CTGTGACCTT TGCCCTCAGC 
CACCGGAAGT CTGTCCCTAA GAGCCCTGTT TTGGCCACCA AACTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_599252.2
CDS	840..3047
Translation	MELQRRDYHVERPLLNQEQLEDLGHWGPAAKTHQWRTWFRCSRARAHSLLLQHVPVLGWLPRYPVREWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPMFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLTADKAFVQGLNATADDARVQVAYTLSFLVGLFQVGLGLVHFGFVVTYLSEPLVRSYTTAASVQVLVSQLKYVFGIKLSSHSGPLSVIYTVLEVCAQLPETVPGTVVTAIVAGVALVLVKLLNEKLHRRLPLPIPGELLTLIGATGISYGVKLNDRFKVDVVGNITTGLIPPVAPKTELFATLVGNAFAIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGFFQCFPVSCSMSRSLVQESTGGNTQVAGAVSSLFILLIIVKLGELFRDLPKAVLAAVIIVNLKGMMKQFSDICSLWKANRVDLLIWLVTFVATILLNLDIGLAVSIVFSLLLVVVRMQLPHYSVLGQVPDTDIYRDVAEYSGAKEVPGVKVFRSSATLYFANAELYSDSLKEKCGVDVDRLITQKKKRIKKQEMKLKRMKKAKKSQKQDASSKISSVSVNVNTNLEDVKSNDVEGSEAKVHQGEELQDVVSSNQEDAKAPTMTSLKSLGLPQPGFHSLILDLSTLSFVDTVCIKSLKNIFRDFREIEVEVYIAACYSPVVAQLEAGHFFDESITKQHVFASVHDAVTFALSHRKSVPKSPVLATKL

Target ORF information:

RefSeq Version	NM_134420.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 26, member 6 (Slc26a6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134420.4

ORF Insert Sequence:

ATGGAGCTGC AGAGGAGAGA CTACCATGTG GAAAGGCCAT TGCTGAACCA GGAGCAGCTA 
GAAGATCTGG GGCATTGGGG CCCAGCGGCG AAGACCCACC AGTGGCGAAC TTGGTTCCGA 
TGCTCCCGTG CTCGGGCCCA TTCTCTTCTG CTCCAGCACG TTCCAGTCCT GGGCTGGTTA 
CCCCGGTATC CTGTGCGTGA ATGGCTCCTG GGTGATCTGT TATCTGGCCT GAGTGTGGCC 
ATCATGCAGC TTCCTCAGGG CTTGGCCTAT GCCCTTCTGG CGGGATTGCC TCCTATGTTT 
GGTCTGTACA GTTCTTTCTA CCCCGTCTTC ATCTACTTCC TGTTTGGTAC CTCCAGACAC 
ATCTCTGTGG GGACCTTTGC TGTAATGTCT GTGATGGTGG GCAGTGTGAC AGAATCTCTG 
ACAGCAGATA AGGCCTTCGT GCAAGGCTTG AATGCCACAG CTGATGATGC ACGCGTGCAG 
GTGGCCTACA CACTCAGCTT CCTGGTCGGC CTCTTCCAGG TGGGGCTGGG CCTGGTACAC 
TTCGGCTTCG TTGTCACCTA CCTGTCAGAG CCTCTGGTCC GCAGCTATAC CACGGCTGCA 
TCTGTGCAAG TCCTCGTCTC TCAGCTCAAG TATGTGTTTG GCATCAAACT CAGCAGTCAC 
TCTGGGCCAC TGTCCGTTAT CTATACAGTG CTGGAGGTCT GTGCCCAGCT CCCTGAGACT 
GTGCCCGGCA CCGTGGTCAC GGCGATTGTG GCAGGAGTGG CCTTGGTACT GGTGAAGCTA 
CTTAATGAGA AGCTGCATCG GCGTCTGCCC CTGCCCATCC CTGGGGAACT ACTCACGCTC 
ATTGGGGCCA CTGGTATTTC CTATGGTGTG AAGCTGAATG ACAGATTCAA GGTCGATGTG 
GTGGGCAACA TCACCACAGG GCTCATACCC CCGGTGGCAC CCAAGACAGA GCTGTTTGCA 
ACGCTTGTGG GAAATGCCTT TGCCATTGCT GTGGTGGGCT TCGCCATTGC CATCTCACTG 
GGGAAGATCT TTGCCCTGAG GCATGGCTAC CGTGTGGACA GTAACCAGGA GCTGGTAGCC 
CTTGGCCTCA GTAACCTCAT TGGAGGCTTC TTCCAGTGCT TCCCCGTGAG CTGCTCCATG 
TCTCGGAGCT TGGTACAGGA GAGCACGGGA GGCAACACAC AGGTTGCTGG AGCTGTATCT 
TCCCTTTTTA TCCTTCTTAT TATCGTCAAA CTTGGGGAAC TCTTCCGAGA CCTGCCCAAG 
GCCGTCCTGG CTGCTGTCAT TATTGTGAAC CTAAAGGGCA TGATGAAGCA GTTCTCAGAC 
ATCTGCTCTC TTTGGAAGGC AAACAGAGTG GACCTGCTAA TCTGGCTGGT GACCTTTGTG 
GCCACAATCC TGCTGAACCT GGACATTGGC CTGGCAGTTT CCATAGTCTT CTCCTTGCTG 
CTCGTGGTCG TCCGAATGCA GCTGCCCCAT TACTCCGTCC TGGGGCAGGT GCCAGATACG 
GATATTTATA GAGACGTGGC AGAATACTCT GGGGCCAAGG AGGTCCCGGG TGTGAAAGTC 
TTCCGTTCCT CAGCCACGCT GTACTTCGCC AATGCTGAGC TCTACAGCGA CTCTCTGAAA 
GAGAAGTGCG GTGTAGATGT TGACCGCCTC ATCACCCAGA AGAAGAAACG AATCAAAAAG 
CAGGAGATGA AGTTAAAGCG AATGAAGAAA GCCAAGAAGT CCCAGAAACA GGATGCTTCT 
TCCAAGATCT CCTCAGTTTC CGTCAACGTC AACACCAACT TGGAAGACGT CAAAAGCAAT 
GACGTCGAGG GCTCTGAGGC CAAGGTGCAC CAAGGGGAGG AGCTTCAGGA TGTAGTCTCC 
AGCAATCAAG AAGATGCCAA GGCCCCAACC ATGACCTCAC TGAAGTCCCT GGGCCTGCCT 
CAGCCAGGCT TCCATAGCCT CATCCTGGAC CTGAGCACCC TCTCCTTTGT GGACACTGTG 
TGCATTAAGA GCCTGAAGAA TATTTTCCGT GACTTCCGGG AGATTGAAGT GGAAGTGTAC 
ATCGCAGCCT GTTACAGTCC TGTGGTCGCC CAGCTTGAAG CTGGACACTT CTTTGATGAA 
TCTATCACTA AGCAGCATGT CTTTGCCTCT GTCCATGACG CTGTGACCTT TGCCCTCAGC 
CACCGGAAGT CTGTCCCTAA GAGCCCTGTT TTGGCCACCA AACTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Action Potential Shortening and Impairment of Cardiac Function by Ablation of
Circulation. Arrhythmia and electrophysiology10(10)(2017 Oct)
Sirish P,Ledford HA,Timofeyev V,Thai PN,Ren L,Kim HJ,Park S,Lee JH,Dai G,Moshref M,Sihn CR,Chen WC,Timofeyeva MV,Jian Z,Shimkunas R,Izu LT,Chiamvimonvat N,Chen-Izu Y,Yamoah EN,Zhang XD

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Slc26a6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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